PVLA Company Profile and Key Details

Short-term trend indicators are mixed aligned (SMA20 67.29%, SMA50 58.7%, SMA200 135.85%). The stock’s 14-day RSI is 82.33 (overbought), while the ATR of 9.89 points to higher daily volatility. The stock remains currently trading near 52-week highs, trading 14.71% below its high and over 713.94% above its low. Average 10-day trading volume of 286.26 thousand shares is in line with the 3-month average of 317.57 thousand, indicating normal recent market interest.

Palvella Therapeutics, Inc. last paid a dividend of 0 per share, Dividend and splits history remains an important factor for investors monitoring long-term returns. A discounted cash flow model estimates fair value at around $37.56. This means the shares are trading above this model’s fair value.

Palvella Therapeutics, Inc. has 11.06 million shares outstanding. The public float is 6.38 million shares, elevated short interest at 7.73% of float. This equals 701.67 thousand shares. The short ratio is 4.28 days. Institutional investors hold 71.24% of the float. Insiders own 22.86%. JENKINS GEORGE M holds 187.17 thousand shares, HERON ELAINE J has 47.81 thousand shares and Goin Kathleen has 0.00 shares. Over the past six months, insider transactions show net selling. They sold 12.13 thousand shares across 4 transactions.

Palvella Therapeutics, Inc. (NASDAQ:PVLA) closed at $114.23 USD, losing -$6.57 (-5.44%) from the previous close of $120.80. The stock is currently mid-range between its 52-week high and low $18.23 and $151.18. With a market capitalization of about $1.35 billion, Palvella Therapeutics, Inc. is classified as a small-cap and shows lower-than-market volatility (beta ~-0.29). Key stats such as the average daily volume over the past year has been around 319.83 thousand shares, volume is running light vs its 52-week average. Headquartered in Wayne, PA, Palvella Therapeutics, Inc. operates in the Healthcare sector and the Biotechnology industry. Led by CEO Wesley H. Kaupinen, the company employs approximately 14 people and listed since January 02, 2015. Palvella Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing and commercializing novel therapies to treat patients serious and rare genetic skin diseases.

Palvella Therapeutics, Inc. trades at a P/E ratio of -38.02, slightly below the S&P 500 average, with a price-to-sales ratio of 0.0 and a price-to-book ratio of 32.38 reflecting a rich premium to book value. The P/FCF stands at -52.61, also below market averages. Compared to sector medians, Palvella Therapeutics, Inc. P/S is trading at a discount to the sector, and the P/B is far higher than peers, underscoring the brand and earnings power premium investors assign to the stock.

Palvella Therapeutics, Inc. generated EPS of $nan over the past year. Five-year average earnings growth is 29.42%. Wall Street analysts project EPS growth of 13.97% annually over the next five years. Analyst sentiment is bullish. Analyst rating data shows there are 7 Strong Buy ratings, 35 Buy ratings, 0 Hold ratings, 0 Sell rating and 0 Strong Sell ratings. Price targets range from $255.00 to $38.00. The high target offers 123.23% upside. The low target suggests -66.73% downside. The mean target is $135.57. This offers 18.68% upside. Palvella Therapeutics, Inc. earnings surprise history is a mixed track record. The quarter that ended November 11, 2025, missed forecasts by 21.18%. The prior quarter beat by 10.26%. Over the last six quarters, Apple has recorded several small beats. These include 15.0% in August 14, 2024.

Palvella Therapeutics, Inc. (NASDAQ:PVLA) shares are flat -6.36% year-to-date currently trading near 52-week highs band. Short-term momentum has been positive over the last quarter, despite recent volatility. Valuation shows Palvella Therapeutics, Inc. trading at a premium to the broader market with a P/E of -38.02. Analyst sentiment is bullish, with the majority of ratings in Buy territory and a mean price target of $120.36, suggesting 5.37% upside. Our AI forecast model points to short-term strength (26.68% over two weeks), a medium-term rise (32.94% over three months), and a longer-term gain (84.51% over one year), with expected trading ranges indicating moderate volatility.

Our AI price prediction model suggests that Palvella Therapeutics, Inc. stock has strong potential for upside but may face short-term weakness followed by gains in the medium and long term. 2-Week Outlook: Projected increase of 26.68%, with price expected at $144.71 by March 31, 2026, within a range of $126.57 to $162.54 3-Month Outlook: Projected rise of 32.94%, reaching $151.86 by June 15, 2026, with a range of $150.60 to $153.13. 1-Year Outlook: Projected gain of 84.51%, with price at $210.77 by March 17, 2027, within a range of $206.46 to $215.49.