How many institutions own PVLA stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own PVLA shares is 96, representing 54.96% of the company's common stock.

Who are the major shareholders selling Palvella Therapeutics, Inc. stock?

RHUMBLINE ADVISERS, in the last quarter, reduced its stake in PVLA by -12.51% restricting it's holding to 8.64 thousand shares of worth nearly $903.92M. MARINER, LLC also lessened -43.95% of the PVLA shares from its portfolio, reducing its holding to 11.62 thousand shares of worth $1.22M. GOLDMAN SACHS GROUP INC also shunned PVLA shares holding by -58.19% last quarter which brought its holding to 98.94 thousand shares worth $10.36M.

Investors who are buying PVLA stock?

As per its latest 13F filing, LEGAL & GENERAL GROUP PLC increased its stake in PVLA by 674.7% in the last quarter. The institutional holder raised its holding to 5.85 thousand shares having worth more than $612.22K. SIGMA PLANNING CORP also added 100% more shares of PVLA to its portfolio, raising its holding to 6.5 thousand shares of worth $680.36K. DEUTSCHE BANK AG\ also increased its PVLA shares holding by 8.7% which brought its holding to 6.59 thousand shares worth $690.19K.

PVLA's major insiders: who are they?

The insider with the most stakes in PVLA is JENKINS GEORGE M , director at the company. Additionally, PVLA stock is highly held by director HERON ELAINE J and Chief Operating Officer Goin Kathleen among others.

Did an insider recently sell PVLA stock?

Company executives, directors, and other insiders own 22.86% percent of Palvella Therapeutics, Inc.'s stock. Within the last six months, there have been 4 transaction(s) in which PVLA insiders have sold stock, totaling 12.13K shares. Insiders that have sold shares include GOIN KATHLEEN.

Which insider recently purchased PVLA stock?

There have been 2 transaction(s) during the past 6-months in which Palvella Therapeutics, Inc. insiders have bought stock, totalling 6400 shares

How much of PVLA does insiders own?

Around 234.98K Palvella Therapeutics, Inc. shares are held by insiders, which represents about 22.86% of PVLA stock.

Who is the insider with the largest stake?

PVLA director, JENKINS GEORGE M holds the largest portfolio of the company's shares. PVLA shares owned by JENKINS total nearly 187.17 thousand.

Which institution holds the most shares in PVLA?

LEGAL & GENERAL GROUP PLC is the largest institutional owner in PVLA which holds 5.85 thousand shares worth $612.22K or 0.05% of the total PVLA shares outstanding followed by SIGMA PLANNING CORP with ownership of 6.5 thousand shares representing 0.06% of the PVLA ownership. DEUTSCHE BANK AG\ is the third largest stakeholder with 6.59 thousand shares or 0.06% of the ownership worth more than $690.19K.

Is Palvella Therapeutics, Inc. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the PVLA is concerned, it is a stock which is optionable.

Is there a short position on PVLA's shares?

Number of PVLA shares short is 701.67K. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding PVLA shares are there?

As of today, 11.06M shares of PVLA are outstanding.

Is there many float in PVLA stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, PVLA has 6.38M shares in float.

PVLA short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for PVLA is 4.28.

Palvella Therapeutics (PVLA) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares6.35

Short Percent Of Float7.73

Shares Outstanding11.06M

Shares Float6.38M

Shares Short701.67K

Short Ratio4.28

7.73%

Short % of Float

6.35%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

22.86% Percentage of Shares held by All Insiders

54.96% Percentage of Shares held by All Institutions

71.24% Percentage of Float held by Institutions

Number of Institutions Holding Shares

Institutional Ownership

About 54.96% of PVLA shares are held by financial institutions. LEGAL & GENERAL GROUP PLC is the top corporate investor, holding 5.85K shares valued at $612.22K. A 0.05% stake in Palvella Therapeutics, Inc. is owned by the company. SIGMA PLANNING CORP owns 6.5K shares valued at $680.36K, which translates its holding of 0.06% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Dec 31, 2025	LEGAL & GENERAL GROUP PLC	0.05%	5.85K	612.22K	5.09K	+674.70%
Dec 31, 2025	SIGMA PLANNING CORP	0.06%	6.5K	680.36K	6.5K	+100.00%
Dec 31, 2025	DEUTSCHE BANK AG\	0.06%	6.59K	690.19K	528	+8.70%
Dec 31, 2025	FEDERATED HERMES, INC.	3.33%	368.04K	38.52M	28.99K	+8.55%
Dec 31, 2025	FMR LLC	2.09%	231.76K	24.26M	121.31K	+109.84%
Dec 31, 2025	INVESCO LTD.	0.49%	54.27K	5.68M	5.66K	+11.65%
Dec 31, 2025	VANGUARD GROUP INC	5.07%	560.62K	58.68M	65.96K	+13.33%
Dec 31, 2025	RHUMBLINE ADVISERS	0.08%	8.64K	903.92M	-1.24K	-12.51%
Dec 31, 2025	MARSHALL WACE, LLP	0.09%	9.48K	992.69K	9.48K	+100.00%
Dec 31, 2025	ALPS ADVISORS INC	0.09%	9.72K	1.02M	4.23K	+77.11%
Dec 31, 2025	WELLS FARGO & COMPANY/MN	0.1%	10.93K	1.14M	3.58K	+48.76%
Dec 31, 2025	LEGATO CAPITAL MANAGEMENT LLC	0.1%	11.39K	1.19M	11.39K	+100.00%
Dec 31, 2025	MARINER, LLC	0.11%	11.62K	1.22M	-9.11K	-43.95%
Dec 31, 2025	SEI INVESTMENTS CO	0.11%	11.72K	1.23M	11.72K	+100.00%
Dec 31, 2025	VERITION FUND MANAGEMENT LLC	0.11%	11.93K	1.25M	11.93K	+100.00%
Dec 31, 2025	TUDOR INVESTMENT CORP ET AL	0.11%	12.5K	1.31M	12.5K	+100.00%
Dec 31, 2025	SWISS NATIONAL BANK	0.13%	14.2K	1.49M	14.2K	+100.00%
Dec 31, 2025	BANK OF NEW YORK MELLON CORP	0.15%	16.26K	1.7M	79	+0.49%
Dec 31, 2025	GOLDMAN SACHS GROUP INC	0.89%	98.94K	10.36M	-137.7K	-58.19%
Dec 31, 2025	FIRST LIGHT ASSET MANAGEMENT, LLC	6.41%	709.14K	74.23M	167.6K	+30.95%
Dec 31, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.16%	17.32K	1.81M	14.52K	+518.39%
Dec 31, 2025	AVIDITY PARTNERS MANAGEMENT LP	0.17%	19.3K	2.02M	19.3K	+100.00%
Dec 31, 2025	NUVEEN, LLC	0.18%	19.58K	2.05M	6.87K	+54.08%
Dec 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.2%	21.63K	2.26M	620	+2.95%
Dec 31, 2025	RAYMOND JAMES FINANCIAL INC	0.2%	22.26K	2.33M	-1.57K	-6.60%
Dec 31, 2025	JANE STREET GROUP, LLC	0.22%	24K	2.51M	24K	+100.00%
Dec 31, 2025	BARCLAYS PLC	0.23%	25.14K	2.63M	15.36K	+157.12%
Dec 31, 2025	ROYCE & ASSOCIATES LP	0.27%	30.01K	3.14M	-19.5K	-39.38%
Dec 31, 2025	BANK OF AMERICA CORP /DE/	0.27%	30.27K	3.17M	25.58K	+545.60%
Dec 31, 2025	UBS GROUP AG	0.33%	36.51K	3.82M	16.07K	+78.60%
Dec 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.35%	38.2K	4M	22.5K	+143.31%
Dec 31, 2025	BIOIMPACT CAPITAL LLC	1.86%	205.75K	21.54M	138.32K	+205.16%
Dec 31, 2025	ARTISAN PARTNERS LIMITED PARTNERSHIP	1.91%	211.55K	22.14M	211.55K	+100.00%
Dec 31, 2025	FRED ALGER MANAGEMENT, LLC	1.36%	150.03K	15.7M	-36.73K	-19.67%
Dec 31, 2025	BALYASNY ASSET MANAGEMENT L.P.	0.98%	108.88K	11.4M	-57.66K	-34.62%
Dec 31, 2025	CAPTION MANAGEMENT, LLC	0.86%	95.3K	9.98M	95.3K	+100.00%
Dec 31, 2025	CLIO ASSET MANAGEMENT LLC	0.83%	91.64K	9.59M	1	0.00%
Dec 31, 2025	SIREN, L.L.C.	0.68%	75K	7.85M	75K	+100.00%
Dec 31, 2025	CLEARBRIDGE INVESTMENTS, LLC	0.55%	60.63K	6.35M	60.63K	+100.00%
Dec 31, 2025	ARTIA GLOBAL PARTNERS LP	0.54%	59.2K	6.2M	59.2K	+100.00%
Dec 31, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	6.53%	722.4K	75.61M	0	0
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.62%	178.99K	18.74M	10.88K	+6.47%
Dec 31, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.7%	77.3K	8.09M	-240.01K	-75.64%
Dec 31, 2025	AWM INVESTMENT COMPANY, INC.	0.63%	69.42K	7.27M	0	0
Dec 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.2%	22.4K	2.34M	-1.3K	-5.48%
Dec 31, 2025	NORTHERN TRUST CORP	0.49%	54.49K	5.7M	487	+0.90%
Dec 31, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.43%	47.68K	4.99M	47.68K	+100.00%
Dec 31, 2025	NEUBERGER BERMAN GROUP LLC	0.41%	44.9K	4.7M	44.9K	+100.00%
Dec 31, 2025	BLUE OWL CAPITAL HOLDINGS LP	0.36%	40.26K	4.21M	-55K	-57.74%
Dec 31, 2025	MORGAN STANLEY	1.99%	220.66K	23.1M	82.16K	+59.32%
Dec 31, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.14%	15.73K	1.65M	15.73K	+100.00%
Dec 31, 2025	VICTORY CAPITAL MANAGEMENT INC	0.13%	14.12K	1.48M	14.12K	+100.00%
Dec 31, 2025	BROWN ADVISORY INC	0.06%	6.38K	667.69K	0	0
Dec 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0.2%	22.53K	2.36M	-67.17K	-74.88%
Dec 31, 2025	SUPERSTRING CAPITAL MANAGEMENT LP	0.23%	25.47K	2.67M	25.47K	+100.00%
Dec 31, 2025	LISANTI CAPITAL GROWTH, LLC	0.37%	41.47K	4.34M	41.47K	+100.00%
Dec 31, 2025	BLACKROCK, INC.	5.05%	559.07K	58.52M	71.45K	+14.65%
Dec 31, 2025	STATE STREET CORP	3.8%	420.46K	44.01M	283.21K	+206.35%
Dec 31, 2025	SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC	3.52%	389.42K	40.76M	354.53K	+1,015.98%
Dec 31, 2025	JENNISON ASSOCIATES LLC	3.5%	387.48K	40.56M	280.57K	+262.44%
Dec 31, 2025	WOODLINE PARTNERS LP	2.72%	300.54K	31.46M	-45.21K	-13.08%
Dec 31, 2025	ALLIANCEBERNSTEIN L.P.	2.43%	269.03K	28.16M	269.03K	+100.00%
Dec 31, 2025	PERCEPTIVE ADVISORS LLC	2.41%	266.29K	27.87M	-128.81K	-32.60%
Dec 31, 2025	ASPIRIANT, LLC	0.05%	5.85K	612.53K	0	0
Dec 31, 2025	PROFUND ADVISORS LLC	0.05%	5.81K	608.45K	5.81K	+100.00%
Dec 31, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.04%	4.26K	445.89K	0	0
Dec 31, 2025	LETKO, BROSSEAU & ASSOCIATES INC	0.03%	3.5K	366.35K	-1.7K	-32.69%
Dec 31, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.03%	3.47K	363.1K	-659	-15.96%
Dec 31, 2025	BVF INC/IL	7.94%	879.01K	92.01M	-282.24K	-24.30%
Dec 31, 2025	SUVRETTA CAPITAL MANAGEMENT, LLC	8.07%	892.4K	93.41M	70K	+8.51%
Dec 31, 2025	SIG BROKERAGE, LP	0.2%	22.5K	2.36M	22.5K	+100.00%
Dec 31, 2025	EVENTIDE ASSET MANAGEMENT, LLC	0.92%	101.75K	10.65M	101.75K	+100.00%
Dec 31, 2025	SAMSARA BIOCAPITAL, LLC	0.95%	104.82K	10.97M	-104.82K	-50.00%
Dec 31, 2025	BAADER BANK AKTIENGESELLSCHAFT	0.03%	3.13K	326.48K	3.13K	+100.00%
Dec 31, 2025	LPL FINANCIAL LLC	0.03%	3.45K	360.9K	3.45K	+100.00%
Dec 31, 2025	FRANKLIN RESOURCES INC	0.04%	4.65K	486.72K	0	0
Dec 31, 2025	JPMORGAN CHASE & CO	0.05%	5.01K	523.98K	668	+15.40%
Dec 31, 2025		0.75%	82.69K	8.65B	82.69K	+100.00%
Sep 30, 2025	AMALGAMATED BANK	0%	234	15K	0	0
Sep 30, 2025	CHUNG WU INVESTMENT GROUP, LLC	0%	200	12.54K	200	+100.00%
Sep 30, 2025	PRIVATE TRUST CO NA	0%	51	3.2K	51	+100.00%
Sep 30, 2025	GROUP ONE TRADING, L.P.	0%	132	8.28M	0	0
Sep 30, 2025	STERLING CAPITAL MANAGEMENT LLC	0%	47	2.95K	20	+74.07%
Sep 30, 2025	STEWARD PARTNERS INVESTMENT ADVISORY, LLC	0%	20	1.25K	20	+100.00%
Sep 30, 2025	GAMMA INVESTING LLC	0%	17	1.07K	17	+100.00%
Sep 30, 2025	CWM, LLC	0%	17	1K	17	+100.00%
Sep 30, 2025	PNC FINANCIAL SERVICES GROUP, INC.	0%	10	627	10	+100.00%
Sep 30, 2025	J. GOLDMAN & CO LP	0.37%	40.69K	2.55M	-15.6K	-27.71%
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.15%	16.19K	1.01M	2.52K	+18.47%
Sep 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.14%	15.7K	984.23K	5.8K	+58.59%
Sep 30, 2025	NUVEEN, LLC	0.11%	12.71K	796.48K	3.8K	+42.67%
Sep 30, 2025	DELTEC ASSET MANAGEMENT LLC	0.11%	12.5K	783.63K	0	0
Sep 30, 2025	CATALIO CAPITAL MANAGEMENT, LP	0.11%	12.01K	752.91K	12.01K	+100.00%
Sep 30, 2025	EVERSEPT PARTNERS, LP	0.1%	11.34K	711.09K	11.34K	+100.00%
Sep 30, 2025	JANE STREET GROUP, LLC	0.09%	10.02K	627.97K	10.02K	+100.00%
Sep 30, 2025	VANGUARD GROUP INC	4.48%	494.66K	31.01M	330.85K	+201.97%
Sep 30, 2025	BLACKROCK, INC.	4.41%	487.62K	30.57M	42.56K	+9.56%
Sep 30, 2025	WOODLINE PARTNERS LP	3.13%	345.75K	21.68M	-99.87K	-22.41%
Sep 30, 2025	FEDERATED HERMES, INC.	3.07%	339.05K	21.25M	339.05K	+100.00%
Sep 30, 2025	NANTAHALA CAPITAL MANAGEMENT, LLC	2.26%	250.06K	15.68M	0	0
Sep 30, 2025	FRED ALGER MANAGEMENT, LLC	1.69%	186.75K	11.71M	173.21K	+1,279.05%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.52%	168.11K	10.54M	-5.88K	-3.38%
Sep 30, 2025	BALYASNY ASSET MANAGEMENT L.P.	1.51%	166.54K	10.44M	166.54K	+100.00%
Sep 30, 2025	FMR LLC	1%	110.45K	6.92M	110.34K	+108,180.39%
Sep 30, 2025	JENNISON ASSOCIATES LLC	0.97%	106.91K	6.7M	106.91K	+100.00%
Sep 30, 2025	AWM INVESTMENT COMPANY, INC.	0.63%	69.42K	4.35M	0	0
Sep 30, 2025	BIOIMPACT CAPITAL LLC	0.61%	67.42K	4.23M	67.42K	+100.00%
Sep 30, 2025	IKARIAN CAPITAL, LLC	0.59%	64.75K	4.06M	64.75K	+100.00%
Sep 30, 2025	NORTHERN TRUST CORP	0.49%	54K	3.39M	-500	-0.92%
Sep 30, 2025	ABRDN PLC	0.46%	51.24K	3.21M	51.24K	+100.00%
Sep 30, 2025	ROYCE & ASSOCIATES LP	0.45%	49.51K	3.1M	-25.01K	-33.56%
Sep 30, 2025	INVESCO LTD.	0.44%	48.61K	3.05M	48.61K	+100.00%
Sep 30, 2025	MILLENNIUM MANAGEMENT LLC	0.24%	26.87K	1.68M	-288.12K	-91.47%
Sep 30, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.23%	25.53K	1.6M	25.53K	+100.00%
Sep 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.21%	23.7K	1.49M	23.7K	+100.00%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.19%	21.01K	1.32M	0	0
Sep 30, 2025	MARINER, LLC	0.19%	20.72K	1.3M	20.72K	+100.00%
Sep 30, 2025	UBS GROUP AG	0.18%	20.44K	1.28M	-22.71K	-52.63%
Sep 30, 2025	CRESSET ASSET MANAGEMENT, LLC	0.16%	17.42K	1.09M	-3.49K	-16.68%
Sep 30, 2025	APIS CAPITAL ADVISORS, LLC	0.09%	10K	626.9K	10K	+100.00%
Sep 30, 2025	RHUMBLINE ADVISERS	0.09%	9.87K	618.8K	-85	-0.85%
Sep 30, 2025	FIRST LIGHT ASSET MANAGEMENT, LLC	4.9%	541.54K	33.95M	541.54K	+100.00%
Sep 30, 2025	BARCLAYS PLC	0.09%	9.78K	612.86K	-2.4K	-19.73%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0.07%	7.35K	460.52K	3.68K	+100.44%
Sep 30, 2025	BROWN ADVISORY INC	0.06%	6.38K	399.9K	6.38K	+100.00%
Sep 30, 2025	RAYMOND JAMES FINANCIAL INC	0.22%	23.84K	1.49M	23.83K	+476,660.00%
Sep 30, 2025	SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC	0.32%	34.9K	2.19M	34.9K	+100.00%
Sep 30, 2025	SECTORAL ASSET MANAGEMENT INC	0.44%	49.12K	3.08M	-46.5K	-48.63%
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.81%	89.7K	5.62M	22.84K	+34.16%
Sep 30, 2025	CLIO ASSET MANAGEMENT LLC	0.83%	91.64K	5.74M	133	+0.15%
Sep 30, 2025	BLUE OWL CAPITAL HOLDINGS LP	0.86%	95.26K	5.97M	-30K	-23.95%
Sep 30, 2025	STATE STREET CORP	1.24%	137.25K	8.6M	55.24K	+67.36%
Sep 30, 2025	MORGAN STANLEY	1.25%	138.51K	8.68M	2.75K	+2.03%
Sep 30, 2025	SAMSARA BIOCAPITAL, LLC	1.9%	209.63K	13.14M	-130.11K	-38.30%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	2.14%	236.63K	14.83M	151.3K	+177.31%
Sep 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	2.87%	317.31K	19.89M	317.31K	+100.00%
Sep 30, 2025	BVF INC/IL	10.51%	1.16M	72.8M	464.69K	+66.71%
Sep 30, 2025	SUVRETTA CAPITAL MANAGEMENT, LLC	7.44%	822.4K	51.56M	107.94K	+15.11%
Sep 30, 2025	PERCEPTIVE ADVISORS LLC	3.57%	395.09K	24.77M	395.09K	+100.00%
Sep 30, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	6.54%	722.4K	45.29M	0	0
Sep 30, 2025	DEUTSCHE BANK AG\	0.05%	6.07K	380.28K	0	0
Sep 30, 2025	ASPIRIANT, LLC	0.05%	5.85K	366.86K	5.85K	+100.00%
Sep 30, 2025	ALPS ADVISORS INC	0.05%	5.49K	343.92K	5.49K	+100.00%
Sep 30, 2025	LETKO, BROSSEAU & ASSOCIATES INC	0.05%	5.2K	325.99K	5.2K	+100.00%
Sep 30, 2025	FRANKLIN RESOURCES INC	0.04%	4.65K	291.51K	4.65K	+100.00%
Sep 30, 2025	JPMORGAN CHASE & CO	0.04%	4.34K	271.95K	1.09K	+33.68%
Sep 30, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.04%	4.26K	267.06K	0	0
Sep 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.04%	4.13K	258.78K	4.13K	+100.00%
Sep 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.03%	2.8K	175.53K	-2.1K	-42.86%
Sep 30, 2025	QUEST PARTNERS LLC	0.02%	2.62K	164.06K	2.62K	+100.00%
Sep 30, 2025	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0.02%	1.97K	123.75K	335	+20.44%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.01%	1.4K	88.02K	-3.23K	-69.68%
Sep 30, 2025	SPIRE WEALTH MANAGEMENT	0.01%	1.02K	63.69K	-1.5K	-59.62%
Sep 30, 2025	LEGAL & GENERAL GROUP PLC	0.01%	755	47.33K	0	0
Sep 30, 2025	AMERITAS INVESTMENT PARTNERS, INC.	0.01%	700	43.88K	0	0
Sep 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0.01%	568	35.61K	568	+100.00%
Sep 30, 2025	ARCHER INVESTMENT CORP	0%	449	28.15K	449	+100.00%
Sep 30, 2025	US BANCORP \DE\	0%	316	19.81K	316	+100.00%
Sep 30, 2025	CITIGROUP INC	0%	276	17.3K	-2.15K	-88.62%
Jun 30, 2025	NUVEEN, LLC	0.08%	8.91K	200.72K	8.91K	+100.00%
Jun 30, 2025	STRID GROUP, LLC	0.16%	18.17K	409.46K	-11.05K	-37.83%
Jun 30, 2025	XTX TOPCO LTD	0.16%	17.7K	398.98K	17.7K	+100.00%
Jun 30, 2025	BLACKROCK, INC.	4.03%	445.05K	10.03M	334.29K	+301.82%
Jun 30, 2025	SAMSARA BIOCAPITAL, LLC	3.07%	339.74K	7.66M	-339.74K	-50.00%
Jun 30, 2025	ADAMS STREET PARTNERS LLC	2.71%	298.99K	6.74M	-110.68K	-27.02%
Jun 30, 2025	NANTAHALA CAPITAL MANAGEMENT, LLC	2.26%	250.06K	5.64M	0	0
Jun 30, 2025	SECTORAL ASSET MANAGEMENT INC	0.87%	95.62K	2.16M	95.62K	+100.00%
Jun 30, 2025	CLIO ASSET MANAGEMENT LLC	0.83%	91.51K	2.06M	91.51K	+100.00%
Jun 30, 2025	STATE STREET CORP	0.74%	82.01K	1.85M	69.95K	+579.91%
Jun 30, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	6.54%	722.4K	16.28M	32.39K	+4.69%
Jun 30, 2025	SUVRETTA CAPITAL MANAGEMENT, LLC	6.46%	714.46K	16.1M	0	0
Jun 30, 2025	BVF INC/IL	6.3%	696.56K	15.7M	0	0
Jun 30, 2025	WOODLINE PARTNERS LP	4.03%	445.62K	10.04M	251.45K	+129.50%
Jun 30, 2025	MORGAN STANLEY	1.23%	135.75K	3.06B	125.85K	+1,270.28%
Jun 30, 2025	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0%	428	9.65M	428	+100.00%
Jun 30, 2025	FMR LLC	0%	102	2.3M	102	+100.00%
Jun 30, 2025	VERMILLION & WHITE WEALTH MANAGEMENT GROUP, LLC	0%	88	1.98K	88	+100.00%
Jun 30, 2025	ROYAL BANK OF CANADA	0%	37	1K	37	+100.00%
Jun 30, 2025	STERLING CAPITAL MANAGEMENT LLC	0%	27	609	27	+100.00%
Jun 30, 2025	TRUVESTMENTS CAPITAL LLC	0%	14	316	0	0
Jun 30, 2025	RAYMOND JAMES FINANCIAL INC	0%	5	113	5	+100.00%
Jun 30, 2025	ALLWORTH FINANCIAL LP	0%	5	113	0	0
Jun 30, 2025	JONES FINANCIAL COMPANIES LLLP	0%	3	66	0	0
Jun 30, 2025	BALYASNY ASSET MANAGEMENT L.P.	0%	0	-	-8.18K	-100.00%
Jun 30, 2025	OPALEYE MANAGEMENT INC.	0%	0	-	-172.36K	-100.00%
Jun 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.6%	66.86K	1.51M	51.6K	+338.18%
Jun 30, 2025	NORTHERN TRUST CORP	0.49%	54.5K	1.23M	37.87K	+227.64%
Jun 30, 2025	TORONTO DOMINION BANK	0.16%	17.5K	394.45K	-1.37K	-7.27%
Jun 30, 2025	BANK OF NEW YORK MELLON CORP	0.12%	13.66K	307.94K	13.66K	+100.00%
Jun 30, 2025	FRED ALGER MANAGEMENT, LLC	0.12%	13.54K	305.24K	13.54K	+100.00%
Jun 30, 2025	DELTEC ASSET MANAGEMENT LLC	0.11%	12.5K	281.75K	0	0
Jun 30, 2025	BARCLAYS PLC	0.11%	12.18K	274K	12.12K	+19,231.75%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0.04%	4.17K	94.08K	-3.44K	-45.14%
Jun 30, 2025	MIRAE ASSET GLOBAL ETFS HOLDINGS LTD.	0.03%	3.75K	84.53K	3.75K	+100.00%
Jun 30, 2025	LEGAL & GENERAL GROUP PLC	0.01%	755	17.02K	755	+100.00%
Jun 30, 2025	AMERITAS INVESTMENT PARTNERS, INC.	0.01%	700	15.78K	700	+100.00%
Jun 30, 2025	WELLS FARGO & COMPANY/MN	0.03%	3.67K	82.61K	3.62K	+7,230.00%
Jun 30, 2025	BLUE OWL CAPITAL HOLDINGS LP	1.13%	125.26K	2.82M	-15K	-10.69%
Jun 30, 2025	ROYCE & ASSOCIATES LP	0.67%	74.52K	1.68M	3K	+4.20%
Jun 30, 2025	AWM INVESTMENT COMPANY, INC.	0.63%	69.42K	1.56M	0	0
Jun 30, 2025	J. GOLDMAN & CO LP	0.51%	56.29K	1.27M	56.29K	+100.00%
Jun 30, 2025	MARSHALL WACE, LLP	0.44%	49.08K	1.11M	18.73K	+61.73%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.09%	9.9K	223.15K	9.9K	+100.00%
Jun 30, 2025	RHUMBLINE ADVISERS	0.09%	9.96K	224.4K	9.96K	+100.00%
Jun 30, 2025		0.01%	1.64K	36.94K	1.64K	+100.00%
Jun 30, 2025	DEUTSCHE BANK AG\	0.05%	6.07K	136.73K	6.07K	+100.00%
Jun 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.04%	4.9K	110.45K	4.9K	+100.00%
Jun 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.04%	4.63K	104.36K	4.63K	+100.00%
Jun 30, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.04%	4.26K	96.02K	4.26K	+100.00%
Jun 30, 2025	JPMORGAN CHASE & CO	0.03%	3.25K	73.14K	3.24K	+108,066.67%
Jun 30, 2025	SPIRE WEALTH MANAGEMENT	0.02%	2.52K	56.71K	0	0
Jun 30, 2025	UBS OCONNOR LLC	0.4%	43.99K	991.63K	-4.67K	-9.60%
Jun 30, 2025	DAFNA CAPITAL MANAGEMENT LLC	0.39%	43.35K	977.06K	0	0
Jun 30, 2025	UBS GROUP AG	0.39%	43.15K	972.58K	33.1K	+329.17%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.19%	21.01K	473.63K	21.01K	+100.00%
Jun 30, 2025	CRESSET ASSET MANAGEMENT, LLC	0.19%	20.91K	471.33K	0	0
Jun 30, 2025	CITIGROUP INC	0.02%	2.43K	54.68K	180	+8.01%
Jun 30, 2025	MILLENNIUM MANAGEMENT LLC	2.85%	314.99K	7.1M	45.15K	+16.73%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.57%	173.99K	3.92M	79.79K	+84.70%
Jun 30, 2025	VANGUARD GROUP INC	1.48%	163.81K	3.69M	25.38K	+18.33%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.77%	85.33K	1.92B	66.28K	+347.85%
Jun 30, 2025	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0.01%	1.64K	36.94K	1.64K	+100.00%
Mar 31, 2025	OPALEYE MANAGEMENT INC.	1.56%	172.36K	4.82M	172.36K	+100.00%
Mar 31, 2025	TRUVESTMENTS CAPITAL LLC	0%	14	392	0	0
Mar 31, 2025	BARCLAYS PLC	0%	63	1K	0	0
Mar 31, 2025	GROUP ONE TRADING, L.P.	0%	312	8.73K	0	0
Mar 31, 2025	WOODLINE PARTNERS LP	1.76%	194.17K	5.43M	194.17K	+100.00%
Mar 31, 2025	NANTAHALA CAPITAL MANAGEMENT, LLC	2.27%	250.06K	7M	0	0
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	2.45%	269.84K	7.55M	269.84K	+100.00%
Mar 31, 2025	ADAMS STREET PARTNERS LLC	3.72%	409.67K	11.47M	0	0
Mar 31, 2025	CITIGROUP INC	0.02%	2.25K	62.87K	1.14K	+102.71%
Mar 31, 2025	MARSHALL WACE, LLP	0.28%	30.35K	849.36K	30.35K	+100.00%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.86%	94.2K	2.64M	79.93K	+560.12%
Mar 31, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0%	0	-	-175	-100.00%
Mar 31, 2025	JPMORGAN CHASE & CO	0%	3	84	-23	-88.46%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0.07%	7.61K	212.98K	7.6K	+63,308.33%
Mar 31, 2025	MORGAN STANLEY	0.09%	9.91K	277.3K	9.82K	+10,786.81%
Mar 31, 2025	UBS GROUP AG	0.09%	10.05K	281.41K	9.85K	+4,877.23%
Mar 31, 2025	TORONTO DOMINION BANK	0.17%	18.87K	528.23K	5.66K	+42.85%
Mar 31, 2025	DAFNA CAPITAL MANAGEMENT LLC	0.39%	43.35K	1.21M	-28.1K	-39.33%
Mar 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	1.04%	114.39K	3.2M	114.39K	+100.00%
Mar 31, 2025	VANGUARD GROUP INC	1.26%	138.43K	3.87M	127.09K	+1,120.53%
Mar 31, 2025	BLUE OWL CAPITAL HOLDINGS LP	1.27%	140.26K	3.93M	-109.8K	-43.91%
Mar 31, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	6.26%	690.01K	19.31M	36.12K	+5.52%
Mar 31, 2025	BVF INC/IL	6.32%	696.56K	19.5M	0	0
Mar 31, 2025	SPIRE WEALTH MANAGEMENT	0.02%	2.52K	70.42K	2.52K	+100.00%
Mar 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0.14%	15.26K	427.07K	-6.11K	-28.60%
Mar 31, 2025	NORTHERN TRUST CORP	0.15%	16.64K	465.61K	16.64K	+100.00%
Mar 31, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	0%	0	-	-144.64K	-100.00%
Mar 31, 2025	JONES FINANCIAL COMPANIES LLLP	0%	3	84	0	0
Mar 31, 2025	STATE STREET CORP	0.11%	12.06K	337.62K	12.06K	+100.00%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.17%	19.05K	533.29K	19.05K	+100.00%
Mar 31, 2025	CRESSET ASSET MANAGEMENT, LLC	0.19%	20.91K	585.3K	0	0
Mar 31, 2025	STRID GROUP, LLC	0.27%	29.22K	817.84K	29.22K	+100.00%
Mar 31, 2025	US BANCORP \DE\	0%	0	-	-138	-100.00%
Mar 31, 2025	ADVISOR GROUP HOLDINGS, INC.	0%	0	-	-7	-100.00%
Mar 31, 2025	CITADEL ADVISORS LLC	0%	0	-	-10.41K	-100.00%
Mar 31, 2025	ACADIAN ASSET MANAGEMENT LLC	0%	0	-	-1.55K	-100.00%
Mar 31, 2025	DELTEC ASSET MANAGEMENT LLC	0.11%	12.5K	349.88K	0	0
Mar 31, 2025	UBS OCONNOR LLC	0.44%	48.66K	1.36M	48.66K	+100.00%
Mar 31, 2025	AWM INVESTMENT COMPANY, INC.	0.63%	69.42K	1.94M	69.42K	+100.00%
Mar 31, 2025	ROYCE & ASSOCIATES LP	0.65%	71.51K	2M	71.51K	+100.00%
Mar 31, 2025	SAMSARA BIOCAPITAL, LLC	6.17%	679.49K	19.02M	0	0
Mar 31, 2025	SUVRETTA CAPITAL MANAGEMENT, LLC	6.49%	714.46K	20M	0	0
Mar 31, 2025	BML CAPITAL MANAGEMENT, LLC	0%	0	-	-42.13K	-100.00%
Mar 31, 2025	WELLS FARGO & COMPANY/MN	0%	50	1.4K	0	0
Mar 31, 2025	BALYASNY ASSET MANAGEMENT L.P.	0.07%	8.18K	228.85K	8.18K	+100.00%
Mar 31, 2025	BLACKROCK, INC.	1.01%	110.76K	3.1M	97.82K	+756.07%
Mar 31, 2025	ALLWORTH FINANCIAL LP	0%	5	128	0	0

Insiders

Among the PVLA insiders holding of 22.86% of the stake in company, JENKINS GEORGE M, director, holds the largest shares of 187.17K. HERON ELAINE J, director, is the second largest PVLA insider with ownership of 47.81K shares. GOIN KATHLEEN, Chief Operating Officer, stands third with possession of 0 shares of that stake.

Insiders	Designation	Shares Held
JENKINS GEORGE M	director	187.17K
HERON ELAINE J	director	47.81K
GOIN KATHLEEN	Chief Operating Officer	0

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Feb 27, 2026	JENKINS GEORGE M	PURCHASE	125.00	4K	500K	187.17K
Feb 27, 2026	HERON ELAINE J	PURCHASE	125.00	2.4K	300K	47.81K
Feb 18, 2026	GOIN KATHLEEN	SALE	79.97	1.28K	102.04K	0
Jan 21, 2026	GOIN KATHLEEN	SALE	97.94	3.75K	367.18K	0
Dec 17, 2025	GOIN KATHLEEN	SALE	96.47	4.3K	415.02K	0
Nov 19, 2025	GOIN KATHLEEN	SALE	86.51	2.8K	242.39K	0
Apr 09, 2025	JENKINS GEORGE M	PURCHASE	20.27	2.49K	50.47K	13.52K
Dec 18, 2024	JENKINS GEORGE M	PURCHASE	12.93	4K	51.72K	180.67K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE6.4K2

SALES12.13K4

NET SHARES-5.73K2

SHARES HELD234.98K6

% NET SHARES-102.44%-66.67%

Frequently Asked Questions