GPCR Company Profile and Key Details

Q: Who are the executives of GPCR?

Dr. Raymond C. Stevens Ph.D.Chief Executive Officer & DirectorDr. Mark A. Bach M.D., Ph.D.Chief Medical OfficerMs. Lani IbarraSenior Vice President of Clinical Devel. OperationsDr. Fang Zhang Ph.D.Executive Vice President & Head of BiologyDr. Yingli Ma Ph.D.Chief Technology OfficerDr. Xichen Lin Ph.D.Chief Scientific OfficerMr. Tony PengSenior Vice President of LegalMs. Melita Sun JungChief Bus. OfficerMr. Jun S. YoonCo- Founder, Chief Financial Officer & Sec.Dr. Hui Lei Ph.D.Senior Vice President of Chemistry

NASDAQ : GPCR

Structure Therapeutics

$49.09

-1.43-2.83%

At Close 4:00 PM

59.54

BESG ScoreESG Rating

Profile Key Stats Analyst Ratings Ownership Ratios Financials Dividend & splits Sentiment Forecast

Price Chart

Stock Price Today

Structure Therapeutics Inc. (GPCR) stock declined over -2.83%, trading at $49.09 on NASDAQ, down from the previous close of $50.52. The stock opened at $50.61, fluctuating between $49.02 and $50.96 in the recent session.

Stock Snapshot

50.52

Prev. Close

2.83B

Market Cap

49.02

Day Low

-31.27

P/E Ratio

-1.57

EPS (TTM)

-1.76

Cash Flow per Share

50.61

Open

57.57M

Number of Shares

50.955

Day High

95.06%

Free Float in %

9.76

Book Value

592.48K

Volume

Relevant Articles

SEC Fillings

Current Report (8-k)

Filing Date	Accepted Date

Annual Report (10-k)

Filing Date	Accepted Date

Stock Price History Chart

Date	Open	High	Low	Close	Volume
Aug 21, 2026	50.70	51.11	49.01	49.09	592.48K
Aug 20, 2026	54.15	54.60	50.33	50.52	1.08M
Aug 19, 2026	54.30	55.35	52.40	54.13	710.04K
Aug 18, 2026	53.70	55.60	52.58	53.53	599.65K
Aug 17, 2026	54.00	54.66	53.00	53.76	305.13K
Aug 14, 2026	54.61	54.99	52.81	54.51	555.82K
Aug 13, 2026	53.91	55.00	52.57	54.70	441.92K
Aug 12, 2026	52.55	53.92	51.00	53.91	1.51M
Aug 11, 2026	53.70	53.70	51.88	52.13	471.75K
Aug 10, 2026	53.19	53.87	51.87	53.81	358.49K
Aug 07, 2026	53.80	54.80	50.83	53.14	329.35K
Aug 06, 2026	50.02	52.78	50.02	52.62	334.5K
Aug 05, 2026	49.98	51.67	49.85	50.53	529.62K
Aug 04, 2026	49.40	50.51	48.30	49.64	867.71K
Aug 03, 2026	48.04	48.71	46.58	48.36	302.76K
Jul 31, 2026	49.50	49.50	46.81	48.04	407.57K
Jul 30, 2026	47.29	49.62	46.40	49.47	379.44K
Jul 29, 2026	47.10	48.69	47.00	47.35	470.33K
Jul 28, 2026	48.41	48.41	46.79	47.89	507.56K
Jul 27, 2026	49.35	51.30	48.69	48.69	464.29K

Contact Details

South San Francisco, CA 94080

United States

https://structuretx.com 628 229 9277

About Company

Structure Therapeutics Inc., an international biopharmaceutical company currently in its clinical development phase, is committed to creating and providing groundbreaking oral therapies for various chronic diseases that lack adequate treatment options. The company's primary investigational drug, GSBR-1290, is an orally administered, biased small molecule agonist designed to target the glucagon-like-peptide-1 receptor (GLP-1R). This G-protein-coupled receptor (GPCR) is a recognized and validated therapeutic target for managing both type-2 diabetes mellitus and obesity. Furthermore, Structure Therapeutics is developing other oral small molecule treatments that act on different GPCRs, addressing pulmonary and cardiovascular conditions. For example, ANPA-0073 is a biased agonist aimed at the apelin receptor, a GPCR linked to diseases like idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension. Another compound in their pipeline is LTSE-2578, an oral small molecule that acts as a lysophosphatidic acid 1 receptor antagonist, also being explored for the treatment of IPF. Established in 2016, the company was formerly known as ShouTi Inc. and is headquartered in South San Francisco, California.

Stock Peers

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7.79+1.44%

Vertex Pharmaceuticals Incorporated$548.05 MDGL

-2.35-0.45%

Madrigal Pharmaceuticals, Inc.$516.74 UTHR

-7.88-1.51%

United Therapeutics Corporation$513.12 PRAX

11.36+3.12%

Praxis Precision Medicines, Inc.$375.94 ONC

5.31+1.44%

BeOne Medicines AG$374.47 KRYS

9.56+2.84%

Krystal Biotech, Inc.$346.58 KRTX

0.09+0.03%

Karuna Therapeutics, Inc.$329.83 LGND

-1.1-0.38%

Ligand Pharmaceuticals Incorporated$286.29

Company Overview

Structure Therapeutics Inc. (NASDAQ:GPCR) closed at $49.09 USD, losing -$1.43 (-2.83%) from the previous close of $50.52. The stock is currently mid-range between its 52-week high and low $18.26 and $94.90. With a market capitalization of about $2.83 billion, Structure Therapeutics Inc. is classified as a mid-cap and shows lower-than-market volatility (beta ~-1.51). Key stats such as the average daily volume over the past year has been around 714.99 thousand shares, in line with its 52-week average. Headquartered in South San Francisco, CA, Structure Therapeutics Inc. operates in the Healthcare sector and the Biotechnology industry. Led by CEO Raymond C. Stevens, the company employs approximately 233 people and listed since February 03, 2023. Structure Therapeutics Inc., an international biopharmaceutical company currently in its clinical development phase, is committed to creating and providing groundbreaking oral therapies for various chronic diseases that lack adequate treatment options.

Technical Performance

GPCR has shown sold momentum, gaining 31.23% over the past week and 232.43% over the past quarter, though year-to-date performance is up 30.87%. Short-term trend indicators are bearishly aligned (SMA20 -13.39%, SMA50 -13.04%, SMA200 70.71%). The stock’s 14-day RSI is 35.57 (weak momentum), while the ATR of 4.14 points to higher daily volatility. The stock remains hovering near 52-week lows, trading -31.77% below its high and over 389.79% above its low. Average 10-day trading volume of 696.12 thousand shares is in line with the 3-month average of 689.08 thousand, indicating normal recent market interest.

Valuation Metrics

Structure Therapeutics Inc. trades at a P/E ratio of -16.46, slightly below the S&P 500 average, with a price-to-sales ratio of 0.0 and a price-to-book ratio of 2.68 suggesting the stock is closer to book value. The P/FCF stands at -12.79, also below market averages.

Dividend & Fair Value

Structure Therapeutics Inc. last paid a dividend of 0 per share, Dividend and splits history remains an important factor for investors monitoring long-term returns. A discounted cash flow model estimates fair value at around $13.40. This means the shares are trading above this model’s fair value.

Earnings & Analyst Outlook

Structure Therapeutics Inc. generated EPS of -$3.65 over the past year. Five-year average earnings growth is -51.75%. The latest quarter delivered EPS of -$0.49. The next quarter is forecast at -$0.37. Next year's EPS is expected at -$14.74. Analyst sentiment is bullish. Analyst rating data shows there are 4 Strong Buy ratings, 10 Buy ratings, 0 Hold ratings, 0 Sell rating and 0 Strong Sell ratings. Price targets range from $140.00 to $70.00. The high target offers 185.19% upside. The low target suggests 42.6% downside. The mean target is $107.07. This offers 118.11% upside. Structure Therapeutics Inc. earnings surprise history is a consistent trend of beating forecasts. The quarter that ended August 06, 2026, missed forecasts by 25.64%. The prior quarter beat by -10.26%. Over the last six quarters, Apple has recorded several small beats. These include 12.5% in May 08, 2025.

Shareholding & Insider Activity

Structure Therapeutics Inc. has 71.07 million shares outstanding. The public float is 54.91 million shares, elevated short interest at 11.97% of float. This equals 6.21 million shares. The short ratio is 7.32 days. Institutional investors hold 98.73% of the float. Insiders own 2.66%. Farid Ramy holds 275.00 thousand shares, FMR LLC has 1.37 thousand shares and Stevens Raymond C has 0.00 shares. Over the past six months, insider transactions show net selling. They sold 13.45 thousand shares across 6 transactions.

Financial & Profitability Overview

Over the trailing twelve months, Structure Therapeutics has not generated any revenue. Returns are negative, with ROA at -18.58% and ROE at -19.77%.
On valuation metrics, Structure Therapeutics trades at a P/E of -16.46, P/S of 0.00 and P/B of 2.68. The current ratio is 20.75 and quick ratio is 20.75. Operationally, the company’s inventory turnover is 0.00 and cash conversion cycle is -3333.94 days , indicating it collects cash faster than it pays suppliers. Debt-to-equity is 0.00, supported by a cash flow-to-debt ratio of -35.36.

Quarterly Financial Highlights

For the quarter ended Dec 31, 2023, Structure Therapeutics posted revenue of $0.00, down slightly from $0.00 in the prior quarter. Gross profit was - $949.17K (margin 0.00%). Operating income was - $102.69M (margin 0.0%). Net income was- $89.54M (EPS - $2.44).
The company ended the quarter with $467.32M in cash and short-term investments, a total debt of $5.45M, and net debt of - $124.34M. Total assets were $482.02M, with equity of $452.97M. Financials further reflected weakness, with operating cash flow of - $79.42M, free cash flow of - $81.58M, and capital expenditures of - $2.17M.

Price Forecast & Outlook

Our AI price prediction model suggests that Structure Therapeutics Inc. stock has strong potential for upside but may face short-term weakness followed by gains in the medium and long term. 2-Week Outlook: Projected increase of 14.38%, with price expected at $56.15 by September 03, 2026, within a range of $53.84 to $58.31 3-Month Outlook: Projected fall of -76.02%, reaching $11.77 by November 18, 2026, with a range of $9.34 to $13.12. 1-Year Outlook: Projected gain of 14.3%, with price at $56.11 by August 20, 2027, within a range of $49.24 to $61.09.

Key Takeaways

Structure Therapeutics Inc. (NASDAQ:GPCR) shares are up 30.87% year-to-date currently trading near 52-week highs band. Short-term momentum has been positive over the last quarter, despite recent volatility. Valuation shows Structure Therapeutics Inc. trading at a premium to the broader market with a P/E of -16.46. Analyst sentiment is bullish, with the majority of ratings in Buy territory and a mean price target of $86.29, suggesting 75.78% upside. Our AI forecast model points to short-term strength (14.38% over two weeks), a medium-term fall (-76.02% over three months), and a longer-term gain (14.3% over one year), with expected trading ranges indicating moderate volatility.

Frequently Asked Questions

What is the current Structure Therapeutics Inc. (GPCR) stock price?

Structure Therapeutics Inc. (NASDAQ: GPCR) stock price is $49.09 in the last trading session. During the trading session, GPCR stock reached the peak price of $50.96 while $49.02 was the lowest point it dropped to. The percentage change in GPCR stock occurred in the recent session was -2.83% while the dollar amount for the price change in GPCR stock was - $1.43.

GPCR's industry and sector of operation?

The NASDAQ listed GPCR is part of Biotechnology industry that operates in the broader Healthcare sector. Structure Therapeutics Inc. designs, manufactures, and markets smartphones, personal computers, tablets, wearables, and accessories worldwide.

Who are the executives of GPCR?

Dr. Raymond C. Stevens Ph.D.
Chief Executive Officer & Director
Dr. Mark A. Bach M.D., Ph.D.
Chief Medical Officer
Ms. Lani Ibarra
Senior Vice President of Clinical Devel. Operations
Dr. Fang Zhang Ph.D.
Executive Vice President & Head of Biology
Dr. Yingli Ma Ph.D.
Chief Technology Officer
Dr. Xichen Lin Ph.D.
Chief Scientific Officer
Mr. Tony Peng
Senior Vice President of Legal
Ms. Melita Sun Jung
Chief Bus. Officer
Mr. Jun S. Yoon
Co- Founder, Chief Financial Officer & Sec.
Dr. Hui Lei Ph.D.
Senior Vice President of Chemistry

How GPCR did perform over past 52-week?

GPCR's closing price is 168.78% higher than its 52-week low of $18.26 where as its distance from 52-week high of $94.90 is -48.27%.

How many employees does GPCR have?

Number of GPCR employees currently stands at 233.

Link for GPCR official website?

Official Website of GPCR is: https://structuretx.com

How do I contact GPCR?

GPCR could be contacted at phone 628 229 9277 and can also be accessed through its website. GPCR operates from 611 Gateway Boulevard, South San Francisco, CA 94080, United States.

How many shares of GPCR are traded daily?

GPCR stock volume for the day was 592.48K shares. The average number of GPCR shares traded daily for last 3 months was 714.99K.

What is the market cap of GPCR currently?

The market value of GPCR currently stands at $2.83B with its latest stock price at $49.09 and 57.57M of its shares outstanding.

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Employees	233
Beta	-1.51
Sales or Revenue	$0.00
5Y Sales Change%	0%
Fiscal Year Ends	December
Sector	Healthcare
Industry	Biotechnology

GPCR Company Profile and Key Details

Structure Therapeutics

Price Chart

Stock Price Today

Stock Snapshot

Relevant Articles

SEC Fillings

Current Report (8-k)

Annual Report (10-k)

Stock Price History Chart

Contact Details

About Company

Company Information

Stock Peers

Company Overview

Technical Performance

Valuation Metrics

Dividend & Fair Value

Earnings & Analyst Outlook

Shareholding & Insider Activity

Financial & Profitability Overview

Quarterly Financial Highlights

Price Forecast & Outlook

Key Takeaways

Frequently Asked Questions

Technical Performance

Financial & Profitability Overview

Quarterly Financial Highlights

Shareholding & Insider Activity

Dividend & Fair Value

Earnings & Analyst Outlook

Company Overview

Valuation Metrics

Price Forecast & Outlook

Key Takeaways