Stock Forecast Chart
Stock Price Prediction Summary
Forecast Score Based on 2 Weeks
Based on our forecast, the price of UPB will decline by -90.70% over the next 2 Weeks and hit $0.90 by Tuesday, March 31, 2026. In that time frame, UPB's share price is expected to range between $0.00 and $6.96.
BearishAverageBullish| Date | Predicted Lower | Predicted | Predicted Upper |
|---|---|---|---|
| Mar 31, 2026 | 0.00 | 0.90 | 6.96 |
| Mar 30, 2026 | 0.00 | 1.57 | 8.01 |
| Mar 27, 2026 | 0.00 | 1.51 | 7.84 |
| Mar 26, 2026 | 0.00 | 2.06 | 8.26 |
| Mar 25, 2026 | 0.00 | 2.77 | 8.79 |
| Mar 24, 2026 | 0.00 | 5.13 | 11.33 |
| Mar 23, 2026 | 0.00 | 5.80 | 12.20 |
| Mar 20, 2026 | 0.00 | 5.74 | 12.30 |
| Mar 19, 2026 | 0.43 | 6.29 | 12.69 |
| Mar 18, 2026 | 0.87 | 7.00 | 13.19 |
UPB shares fell -10.76% in Wednesday, March 18, 2026's trading session, dropping from a previous close of $9.71 to move at $8.67. The stock demonstrated notable intraday movement (see UPB's key stats for a full breakdown), fluctuating between $8.66 and $9.63, a +11.21% trading range. While recent weeks have seen some volatility, UPB has managed to secure a +17.73% gain over the past 2 weeks. The downward price movement was accompanied by decreased trading volume, with approximately 719.5K shares changing hands, 194.9K fewer than the previous session. This amounted to $6.23M in total market activity.
Will UPB Continue Its Downward Trend?
According to analyst ratings and projections for UPB, Upstream Bio, Inc. shares are anticipated to decrease by -24.45%, potentially reaching $6.96 per share by March 31, 2026. Short-term technical indicators for UPB currently suggest a bearish sentiment. This aligns with the stock's recent performance, as it has recorded 17 negative trading days within the past 30 sessions. Based on the UPB stock forecast, now is not the best time to buy UPB stock because its current trading price is +859.47% above our predicted value, hinting at a possible undervaluation. For deeper insights, view our sentiment analysis on UPB covering social and institutional perspectives.
UPB Technical Momentum: Overbought, Oversold, or Neutral?
An analysis of Relative Strength Index (RSI) indicators provides insight into UPB's momentum. Short-term RSIs (9, 14, and 20-day figures ranging from 31.22% to 36.64%) suggest the stock is in a weak bearish momentum phase. The 50-day RSI, at 38.00%, hints at potential weakness developing in the medium term. Meanwhile, the 100-day RSI, at 43.25%, maintains a neutral outlook for the long term. Insights into UPB's shareholder base show how institutional investors are positioning themselves during these momentum shifts
Upstream Bio Short-Term Forecasts
UPB Forecast For Next 5 Days
Our algorithm anticipates Upstream Bio (UPB) stock could hit $4.99 by Mar 25, 2026. This represents a -42.43% fall from today's price, following a -2.08% change over the past five days.
UPB Forecast For Next 30 Days
Based on analysis of market trends, the outlook for Upstream Bio, Inc. (UPB) stock over the next 30 days is largely negative. Price forecasts suggest an average target of $3.20, which would mean a -63.07% decrease from the current price of $8.67. Projections for this period range from a high of $12.03 to a low of $0.00.
UPB Forecast For Next 90 Days
Our proprietary market analysis suggests predictions for Upstream Bio's price over the next three months point to a rise. UPB stock is expected to peak at $64.90 on Jun 16, 2026 after potentially dipping to $6.93 on Apr 08, 2026. On average, UPB is likely to trade around $30.40 in the coming 90 days.
Upstream Bio Stock Forecast 2025
Based on our predictive models, Upstream Bio (UPB) is expected to trade between $6.93 and $97.55 throughout 2026. This would result in an average price of $47.92, potentially offering investors a +453.03% return from current levels.
Upstream Bio, Inc. Monthly Forecast 2026–2027
March 2026
According to our latest forecast models, Upstream Bio, Inc. (UPB) is positioned to show a strong performance in March 2026. The price is predicted to move between $9.20 and $14.85, settling at an average of $11.88. This could translate to a +37.10% gain.
April 2026
Based on current market signals, Upstream Bio, Inc. is projected to trend april 2026. We forecast a trading range from $6.93 to $33.72, with a likely average price of $18.80. Investors could expect a potential return of +116.96%.
May 2026
Our predictive algorithms indicate Upstream Bio, Inc. stock may see a shift in May 2026. The expected range spans $30.70–$41.42, with an average target of $34.88. This represents a positive outlook and a possible gain of +302.54%.
June 2026
Analyzing established trends, Upstream Bio, Inc. looks set to move in June 2026. Projections place the stock between $42.45 and $70.21, averaging around $59.59. This suggests a +587.71% gain from current levels.
July 2026
Market indicators suggest Upstream Bio, Inc. could experience notable changes during July 2026. Prices could fluctuate within $28.45 to $69.23, with a midpoint forecast of $42.18. The stock might deliver a +386.79% gain.
August 2026
Forecasting for August 2026, models estimate that Upstream Bio, Inc. may undergo key fluctuations. If trends hold, the stock might trade between $36.08 and $43.21, averaging $40.91. This signals a positive trajectory with potential returns around +372.13%.
September 2026
According to our latest forecast models, Upstream Bio, Inc. (UPB) is positioned to show a strong performance in September 2026. The price is predicted to move between $36.70 and $49.78, settling at an average of $43.39. This could translate to a +400.75% gain.
October 2026
Based on current market signals, Upstream Bio, Inc. is projected to trend october 2026. We forecast a trading range from $47.56 to $67.32, with a likely average price of $58.84. Investors could expect a potential return of +579.05%.
November 2026
Our predictive algorithms indicate Upstream Bio, Inc. stock may see a shift in November 2026. The expected range spans $70.49–$97.55, with an average target of $86.70. This represents a positive outlook and a possible gain of +900.58%.
December 2026
Analyzing established trends, Upstream Bio, Inc. looks set to move in December 2026. Projections place the stock between $46.52 and $96.30, averaging around $62.84. This suggests a +625.22% gain from current levels.
January 2027
Market indicators suggest Upstream Bio, Inc. could experience notable changes during January 2027. Prices could fluctuate within $46.54 to $54.78, with a midpoint forecast of $50.82. The stock might deliver a +486.50% gain.
February 2027
Forecasting for February 2027, models estimate that Upstream Bio, Inc. may undergo key fluctuations. If trends hold, the stock might trade between $10.98 and $46.04, averaging $26.54. This signals a positive trajectory with potential returns around +206.29%.
March 2027
According to our latest forecast models, Upstream Bio, Inc. (UPB) is positioned to show a strong performance in March 2027. The price is predicted to move between $12.15 and $24.93, settling at an average of $18.04. This could translate to a +108.19% gain.
UPB's history of dividends and stock splits also plays a role in long-term investor confidence.