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SYRE Stock Performance and Key Statistics

NASDAQ : SYRE

Spyre Therapeutics

$30.61
0.47+1.56%
At Close 4:00 PM
69.16
ESG ScoreESG Rating

stock performance chart

SYRE Fundamental Analysis

Based on recent data, Spyre Therapeutics, Inc. (SYRE) shows an Average True Range (ATR) of 1.59 and an Enterprise Value of N/A. Its average trading volume over the past 3 months is 896.23K, indicating liquidity. These fundamental metrics provide insight into SYRE's underlying financial health and market activity.

ATR1.59
Enterprise Value-
Avg Vol (3 Months)896.23K
Avg Vol (10 Days)670.5K

SYRE Technical Analysis Indicators

Spyre Therapeutics, Inc. (SYRE) technical indicators as of January 11, 2026: the SMA 20 is -5.45%, SMA 50 at 5.9%, and SMA 200 at 57.59%. The RSI 14 value is 47.89, suggesting its current momentum. These technical analysis signals help assess SYRE's price trends and potential future movements.

SMA 20-5.45%
SMA 505.9%
SMA 20057.59%
RSI 1447.89

SYRE Stock Performance Overview

Spyre Therapeutics, Inc. (SYRE) stock performance overview as of January 11, 2026: The 52-week high is $35.31 (currently -13.31% below), and the 52-week low is $10.91 (currently 180.57% above). Over the past year, SYRE's performance is 26.37%, compared to the S&P 500's 12.34% change.

52-Week High35.31
52-Week High Chg-13.31%
52-Week Low10.91
52-Week Low Chg+180.57%
S&P 500 52-Week Chg12.34%

Spyre Therapeutics, Inc. (SYRE) Historical Stock Performance

According to market data, Spyre Therapeutics, Inc. (SYRE) stock's recent performance metrics show that over the last month, SYRE is -9.9%, with a Year-to-Date (YTD) performance of -8%. Over the past year, the stock has seen a 26.37% change. These figures summarize SYRE's price movements across various periods, reflecting its historical returns.

Period1 Week1 MonthQuarterHalf Year1 YearYTD
High31.6935.3135.3135.3135.3133.31
Low282817.6514.5110.9128
Performance-8.00%-9.90%+88.14%+82.11%+26.37%-8.00%

Industry Analysis and Valuation

According to current financial data, SYRE stock's P/E (TTM) ratio is -15.40, which compares to the S&P 500's P/E of 32.59. The sector median P/E is -1.24. Key valuation ratios for SYRE, including P/S (N/A), P/B (5.04), and P/FCF (-11.42), offer insights into how the company is valued relative to its earnings, sales, book value, and free cash flow.

ValuationSYRESector MedianIndustry AvgS&P 500
P/E (TTM)-15.4-1.24-5.1632.59
P/S (TTM)N/A3.71465.95.98
P/B (TTM)5.040.19-335.26.24
P/FCF (TTM)-11.42-8.97-394.5336.55

Frequently Asked Questions

How is SYRE price-to-earnings ratio currently?
SYRE has a current P/E ratio of -15.4
How are SYRE's price-to-sale and price-to-book ratios?
The SYRE stock has a trailing twelve month price-to sales (P/S) ratio of N/A while its price-to-book (P/B) value is 5.04.
Is Spyre Therapeutics, Inc.'s price-to-cashflow ratio high or low?
SYRE's price-to-free-cashflow (P/FCF) ratio is -11.42, an indicator that is currently being trending upward.
What's current simple moving average (SMA) for SYRE?
Based on SYRE's recent bid, its distance from 20 days simple moving average is -5.45%. It is 5.9% apart from 50 days simple moving average, and it is 57.59% apart from 200 days simple moving average.
What is the 52-week price range for SYRE?
The 52-week high for SYRE is $35.31 which is -13.31% away from the current price level whereas the distance of that from the 52-week low of $10.91 stands at 180.57%.
An overview of SYRE's stock performance: how did it fare?
The performance of SYRE stock was not encouraging with most of its significant price indicators in red. Spyre Therapeutics, Inc.(NASDAQ: SYRE) shares have moved upward +1.56% or $0.47 in the latest trading session and have lost -8% year-to-date (YTD). The stock has gained nearly 26.37% over the past year. After moving 88.14% over the trailing 3-month period, the stock is 82.11% higher in the 6-month period. Looking at its performance over the shorter term, it'slost -8% a week and -9.9% a month.
What is SYRE's 14-day relative strength index (RSI)?
The current 14-day RSI for SYRE stock is 47.89. Investors and traders alike rely on the relative strength index, or RSI, as an oscillating indicator. In terms of values, the RSI operates within a range ranging from 0 to 100. A rising RSI line indicates strength in the shares. As the RSI line falls, the opposite occurs. It is possible to examine different time periods when using the RSI indicator. Shorter time frames can cause the RSI to be more volatile. Most traders pay close attention to the marks between 30 and 70 on the RSI scale. When the stock price moves over 70, it is often considered to be an indicator of overbought conditions. Dropping below 30 indicates oversold territory. These levels are often used by traders to forecast stock price reversals.
For SYRE, what is the average true range (ATR) for the past two weeks?
ATR stands for Average True Range, which may be useful when traders or investors are assessing technical inventory. Currently, Spyre Therapeutics, Inc. (SYRE) has a 14-day ATR of 1.59.
What is SYRE's current enterprise value?
After closing at $30.14 with 60.4M of its shares outstanding, the current enterprise value of SYRE is roughly -.
Over the past year, how has the stock price of SYRE changed?
Spyre Therapeutics, Inc. (NASDAQ: SYRE) is up 26.37% when it comes to the percentage price change over the past 52-weeks. The percentage price change came more than that of broader S&P 500 index that came at a rise of 12.34%. SYRE stock price is also down -8% on its value in year-to-date trading.
What is the average trading volume for SYRE shares?
The number outstanding shares of SYRE is 60.4M, and of these 77.38% shares are freely available for trading. On average, SYRE stock has traded 670.5K shares per day for the past 10 days. A total of 445.73K shares changed hands during the last trading session with the average session volume of 919.43K shares.
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