How many institutions own XLO stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own XLO shares is 26, representing 51.84% of the company's common stock.

Who are the major shareholders selling Xilio Therapeutics, Inc. stock?

GILEAD SCIENCES, INC., in the last quarter, reduced its stake in XLO by -92.86% restricting it's holding to 650.39 thousand shares of worth nearly $5.47M. EMPERY ASSET MANAGEMENT, LP also lessened -100% of the XLO shares from its portfolio, reducing its holding to 0 shares of worth -. STONEPINE CAPITAL MANAGEMENT, LLC also shunned XLO shares holding by -100% last quarter which brought its holding to 0 shares worth -.

Investors who are buying XLO stock?

As per its latest 13F filing, GHISALLO CAPITAL MANAGEMENT LLC increased its stake in XLO by 100% in the last quarter. The institutional holder raised its holding to 13.8 thousand shares having worth more than $116.06K. ROYAL BANK OF CANADA also added 100% more shares of XLO to its portfolio, raising its holding to 91 shares of worth $1.00K. JPMORGAN CHASE & CO also increased its XLO shares holding by 100% which brought its holding to 240 shares worth $1.98K.

XLO's major insiders: who are they?

The insider with the most stakes in XLO is GILEAD SCIENCES, INC. , 10 percent owner at the company. Additionally, XLO stock is highly held by 10 percent owner Bain Capital Life Sciences Investors, LLC and 10 percent owner SV7 Impact Medicine Fund LP among others.

Did an insider recently sell XLO stock?

Company executives, directors, and other insiders own 28.58% percent of Xilio Therapeutics, Inc.'s stock. Within the last six months, there have been 0 transaction(s) in which XLO insiders have sold stock, totaling 0 shares. Insiders that have sold shares include BRENNAN KEVIN M., FRANKENFIELD CHRISTOPHER JAMES, and ATLAS VENTURE FUND XI, L.P..

Which insider recently purchased XLO stock?

There have been 2 transaction(s) during the past 6-months in which Xilio Therapeutics, Inc. insiders have bought stock, totalling 3744000 shares

How much of XLO does insiders own?

Around 40.39M Xilio Therapeutics, Inc. shares are held by insiders, which represents about 28.58% of XLO stock.

Who is the insider with the largest stake?

XLO 10 percent owner, GILEAD SCIENCES, INC. holds the largest portfolio of the company's shares. XLO shares owned by GILEAD total nearly 40.38 million.

Which institution holds the most shares in XLO?

GHISALLO CAPITAL MANAGEMENT LLC is the largest institutional owner in XLO which holds 13.8 thousand shares worth $116.06K or 0.01% of the total XLO shares outstanding followed by GILEAD SCIENCES, INC. with ownership of 650.39 thousand shares representing 0.78% of the XLO ownership. EMPERY ASSET MANAGEMENT, LP is the third largest stakeholder with 0 shares or 0% of the ownership worth more than -.

Is Xilio Therapeutics, Inc. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the XLO is concerned, it is a stock which is not optionable.

Is there a short position on XLO's shares?

Number of XLO shares short is 4.30M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding XLO shares are there?

As of today, 51.83M shares of XLO are outstanding.

Is there many float in XLO stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, XLO has 23.43M shares in float.

XLO short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for XLO is 9.4.

Xilio Therapeutics (XLO) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableNo

Short Percent Of Outstanding Shares8.3

Short Percent Of Float12.14

Shares Outstanding51.83M

Shares Float23.43M

Shares Short4.30M

Short Ratio9.4

12.14%

Short % of Float

8.3%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

28.58% Percentage of Shares held by All Insiders

51.84% Percentage of Shares held by All Institutions

72.58% Percentage of Float held by Institutions

Number of Institutions Holding Shares

Institutional Ownership

About 51.84% of XLO shares are held by financial institutions. GHISALLO CAPITAL MANAGEMENT LLC is the top corporate investor, holding 13.8K shares valued at $116.06K. A 0.01% stake in Xilio Therapeutics, Inc. is owned by the company. GILEAD SCIENCES, INC. owns 650.39K shares valued at $5.47M, which translates its holding of 0.78% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Mar 31, 2026	GHISALLO CAPITAL MANAGEMENT LLC	0.01%	13.8K	116.06K	13.8K	+100.00%
Mar 31, 2026	GILEAD SCIENCES, INC.	0.78%	650.39K	5.47M	-8.46M	-92.86%
Mar 31, 2026	EMPERY ASSET MANAGEMENT, LP	0%	0	-	-1.18M	-100.00%
Mar 31, 2026	STONEPINE CAPITAL MANAGEMENT, LLC	0%	0	-	-126.27K	-100.00%
Mar 31, 2026	CITADEL ADVISORS LLC	0%	0	-	-436.22K	-100.00%
Mar 31, 2026	LPL FINANCIAL LLC	0%	0	-	-21K	-100.00%
Mar 31, 2026	MARINER, LLC	0%	0	-	-25K	-100.00%
Mar 31, 2026	GSA CAPITAL PARTNERS LLP	0%	0	-	-147.97K	-100.00%
Mar 31, 2026	GEODE CAPITAL MANAGEMENT, LLC	0%	0	-	-328.97K	-100.00%
Mar 31, 2026	TWO SIGMA INVESTMENTS, LP	0%	0	-	-62.03K	-100.00%
Mar 31, 2026	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0%	0	-	-56.08K	-100.00%
Mar 31, 2026	RENAISSANCE TECHNOLOGIES LLC	0%	0	-	-344.42K	-100.00%
Mar 31, 2026	JANE STREET GROUP, LLC	0%	0	-	-42.08K	-100.00%
Mar 31, 2026	MORGAN STANLEY	0%	0	-	-839.85K	-100.00%
Mar 31, 2026	INVESTORS ASSET MANAGEMENT OF GEORGIA INC /GA/ /ADV	0%	0	-	-10K	-100.00%
Mar 31, 2026	RAYMOND JAMES FINANCIAL INC	0%	0	-	-18.76K	-100.00%
Mar 31, 2026	MERCK & CO., INC.	0%	0	-	-1.48M	-100.00%
Mar 31, 2026	STATE STREET CORP	0%	0	-	-186.39K	-100.00%
Mar 31, 2026	NORTHERN TRUST CORP	0%	0	-	-66.61K	-100.00%
Mar 31, 2026	BANK OF AMERICA CORP /DE/	0%	0	-	-261	-100.00%
Mar 31, 2026	ROYAL BANK OF CANADA	0%	91	1K	91	+100.00%
Mar 31, 2026	JPMORGAN CHASE & CO	0%	240	1.98K	240	+100.00%
Mar 31, 2026	CWM, LLC	0%	4.21K	35.37K	4.21K	+100.00%
Mar 31, 2026	CALIGAN PARTNERS LP	0.07%	112.13K	943K	112.13K	+100.00%
Mar 31, 2026	KEY FINANCIAL INC	0%	0	-	-830	-100.00%
Mar 31, 2026	POINT72 ASSET MANAGEMENT, L.P.	0%	0	-	-4M	-100.00%
Mar 31, 2026	UBS GROUP AG	0%	0	-	-203	-100.00%
Mar 31, 2026	VANGUARD GLOBAL ADVISERS, LLC	0%	210	1.77K	210	+100.00%
Mar 31, 2026	VANGUARD FIDUCIARY TRUST CO	0.02%	28.48K	239.48K	28.48K	+100.00%
Mar 31, 2026	AJU IB INVESTMENT CO., LTD.	0%	0	-	-667.74K	-100.00%
Mar 31, 2026		0.08%	123.66K	1.04M	123.66K	+100.00%
Mar 31, 2026	HRT FINANCIAL LP	0%	0	-	-31.89K	-100.00%
Mar 31, 2026	PINNACLE FINANCIAL GROUP, LLC / IL	0%	0	-	-10K	-100.00%
Mar 31, 2026	DUNHILL FINANCIAL, LLC	0%	0	-	-10.27K	-100.00%
Mar 31, 2026	STEMPOINT CAPITAL LP	0%	0	-	-2.03M	-100.00%
Mar 31, 2026	PRIVATE WEALTH MANAGEMENT GROUP, LLC	0%	0	-	-310	-100.00%
Mar 31, 2026	FMR LLC	0%	0	-	-511.82K	-100.00%
Mar 31, 2026	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	0%	0	-	-7.37M	-100.00%
Mar 31, 2026	BLACKROCK, INC.	0%	0	-	-2.04K	-100.00%
Mar 31, 2026	SIO CAPITAL MANAGEMENT, LLC	0%	0	-	-2.13M	-100.00%
Mar 31, 2026	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	0.26%	422.51K	3.55M	422.51K	+100.00%
Mar 31, 2026	VELAN CAPITAL INVESTMENT MANAGEMENT LP	0.01%	14.29K	120.14K	14.29K	+100.00%
Mar 31, 2026	XTX TOPCO LTD	0%	0	-	-17.3K	-100.00%
Dec 31, 2025	MERCK & CO., INC.	1.03%	1.48M	949.9K	0	0
Dec 31, 2025	DUNHILL FINANCIAL, LLC	0.01%	10.27K	6.58K	0	0
Dec 31, 2025	STONEPINE CAPITAL MANAGEMENT, LLC	0.09%	126.27K	80.84K	126.27K	+100.00%
Dec 31, 2025	GSA CAPITAL PARTNERS LLP	0.1%	147.97K	95K	147.97K	+100.00%
Dec 31, 2025	STATE STREET CORP	0.13%	186.39K	119.33K	22.5K	+13.73%
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.23%	328.97K	210.63K	0	0
Dec 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0.24%	344.42K	220.5K	139.72K	+68.25%
Dec 31, 2025	AJU IB INVESTMENT CO., LTD.	0.46%	667.74K	427.49K	0	0
Dec 31, 2025	MORGAN STANLEY	0.58%	839.85K	537.67K	-122.07K	-12.69%
Dec 31, 2025	EMPERY ASSET MANAGEMENT, LP	0.82%	1.18M	757.38K	1.18M	+100.00%
Dec 31, 2025	VANGUARD GROUP INC	0.87%	1.26M	803.64K	0	0
Dec 31, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	4.1%	5.92M	3.79M	5.92M	+100.00%
Dec 31, 2025	GILEAD SCIENCES, INC.	6.32%	9.11M	5.83M	0	0
Dec 31, 2025	JANE STREET GROUP, LLC	0.03%	42.08K	26.94K	42.08K	+100.00%
Dec 31, 2025	NORTHERN TRUST CORP	0.05%	66.61K	42.64K	0	0
Dec 31, 2025	XTX TOPCO LTD	0.01%	17.3K	11.08K	-58.74K	-77.25%
Dec 31, 2025	RAYMOND JAMES FINANCIAL INC	0.01%	18.76K	12.01K	0	0
Dec 31, 2025	LPL FINANCIAL LLC	0.01%	21K	13.44K	-10K	-32.26%
Dec 31, 2025	MARINER, LLC	0.02%	25K	16.01K	0	0
Dec 31, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.04%	56.08K	35.9K	0	0
Dec 31, 2025	TWO SIGMA INVESTMENTS, LP	0.04%	62.03K	39.71K	-25.76K	-29.34%
Dec 31, 2025	CITADEL ADVISORS LLC	0.3%	436.22K	279.27K	436.22K	+100.00%
Dec 31, 2025	FEDERATION DES CAISSES DESJARDINS DU QUEBEC	0%	0	-	-3.3K	-100.00%
Dec 31, 2025	SEVENBRIDGE FINANCIAL GROUP, LLC	0%	0	-	-25K	-100.00%
Dec 31, 2025	APTUS CAPITAL ADVISORS, LLC	0%	0	-	-25K	-100.00%
Dec 31, 2025	TWO SIGMA ADVISERS, LP	0%	0	-	-29.69K	-100.00%
Dec 31, 2025	TWO SIGMA SECURITIES, LLC	0%	0	-	-32.13K	-100.00%
Dec 31, 2025	TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK	0%	0	-	-249.64K	-100.00%
Dec 31, 2025	BALYASNY ASSET MANAGEMENT L.P.	0%	0	-	-198.86K	-100.00%
Dec 31, 2025	CITIGROUP INC	0%	0	-	-258	-100.00%
Dec 31, 2025	UBS GROUP AG	0%	203	130	-13.45K	-98.51%
Dec 31, 2025	BANK OF AMERICA CORP /DE/	0%	261	167	15	+6.10%
Dec 31, 2025	PRIVATE WEALTH MANAGEMENT GROUP, LLC	0%	310	199	0	0
Dec 31, 2025	KEY FINANCIAL INC	0%	830	531	0	0
Dec 31, 2025	PINNACLE FINANCIAL GROUP, LLC / IL	0.01%	10K	6.4K	0	0
Dec 31, 2025	FMR LLC	0.36%	511.82K	327.67K	0	0
Dec 31, 2025	GHISALLO CAPITAL MANAGEMENT LLC	0.77%	1.11M	712.69K	1.11M	+100.00%
Dec 31, 2025	STEMPOINT CAPITAL LP	1.41%	2.03M	1.3M	2.03M	+100.00%
Dec 31, 2025	SIO CAPITAL MANAGEMENT, LLC	1.48%	2.13M	1.37M	2.13M	+100.00%
Dec 31, 2025	POINT72 ASSET MANAGEMENT, L.P.	2.78%	4M	2.56M	4M	+100.00%
Dec 31, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	5.12%	7.37M	4.72M	2.81M	+61.44%
Dec 31, 2025	SQUAREPOINT OPS LLC	0%	0	-	-328.79K	-100.00%
Dec 31, 2025	BLACKROCK, INC.	0%	2.04K	1.3K	0	0
Dec 31, 2025	VELAN CAPITAL INVESTMENT MANAGEMENT LP	0.12%	170K	108.83K	170K	+100.00%
Dec 31, 2025	HRT FINANCIAL LP	0.02%	31.89K	20K	7.15K	+28.91%
Dec 31, 2025	INVESTORS ASSET MANAGEMENT OF GEORGIA INC /GA/ /ADV	0.01%	10K	6.4K	0	0
Sep 30, 2025	TWO SIGMA INVESTMENTS, LP	0.09%	87.79K	73.98K	9.76K	+12.51%
Sep 30, 2025	STATE STREET CORP	0.17%	163.89K	138.11K	120.5K	+277.71%
Sep 30, 2025	BALYASNY ASSET MANAGEMENT L.P.	0.21%	198.86K	167.58K	0	0
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.21%	204.7K	172.5K	40.5K	+24.66%
Sep 30, 2025	TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK	0.26%	249.64K	210.44K	0	0
Sep 30, 2025	SQUAREPOINT OPS LLC	0.34%	328.79K	277.08K	93.34K	+39.64%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.34%	328.97K	277.26K	-40.69K	-11.01%
Sep 30, 2025	FMR LLC	0.53%	511.82K	431.31K	0	0
Sep 30, 2025	AJU IB INVESTMENT CO., LTD.	0.69%	667.74K	595.56K	0	0
Sep 30, 2025	MORGAN STANLEY	1%	961.92K	810.61K	-482.41K	-33.40%
Sep 30, 2025	VANGUARD GROUP INC	1.3%	1.26M	1.06M	104.67K	+9.09%
Sep 30, 2025	TAKEDA PHARMACEUTICAL CO LTD	1.53%	1.48M	1.24M	0	0
Sep 30, 2025	MERCK & CO., INC.	1.54%	1.48M	1.25M	0	0
Sep 30, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	4.74%	4.57M	3.85M	0	0
Sep 30, 2025	GILEAD SCIENCES, INC.	9.44%	9.11M	7.67M	0	0
Sep 30, 2025	APTUS CAPITAL ADVISORS, LLC	0.03%	25K	21.07K	0	0
Sep 30, 2025	TWO SIGMA ADVISERS, LP	0.03%	29.69K	25.02K	29.69K	+100.00%
Sep 30, 2025	KEY FINANCIAL INC	0%	830	691	0	0
Sep 30, 2025	SEVENBRIDGE FINANCIAL GROUP, LLC	0.03%	25K	19.33K	0	0
Sep 30, 2025	DUNHILL FINANCIAL, LLC	0.01%	10.27K	8.66K	0	0
Sep 30, 2025	PRIVATE WEALTH MANAGEMENT GROUP, LLC	0%	310	262	0	0
Sep 30, 2025	PINNACLE FINANCIAL GROUP, LLC / IL	0.01%	10K	8.43K	0	0
Sep 30, 2025	GHISALLO CAPITAL MANAGEMENT LLC	0%	0	-	-1.33M	-100.00%
Sep 30, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0%	0	-	-15.41K	-100.00%
Sep 30, 2025	UBS GROUP AG	0.01%	13.65K	11.51K	-226.32K	-94.31%
Sep 30, 2025	RAYMOND JAMES FINANCIAL INC	0.02%	18.76K	15.81K	0	0
Sep 30, 2025	HRT FINANCIAL LP	0.03%	24.74K	20K	24.74K	+100.00%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0%	246	207	-85	-25.68%
Sep 30, 2025	CITIGROUP INC	0%	258	217	258	+100.00%
Sep 30, 2025	FEDERATION DES CAISSES DESJARDINS DU QUEBEC	0%	3.3K	2.78K	0	0
Sep 30, 2025	INVESTORS ASSET MANAGEMENT OF GEORGIA INC /GA/ /ADV	0.01%	10K	8.43K	0	0
Sep 30, 2025	AVANTAX PLANNING PARTNERS, INC.	0%	0	-	-142.34K	-100.00%
Sep 30, 2025	BLACKROCK, INC.	0%	2.04K	1.72K	0	0
Sep 30, 2025	TWO SIGMA SECURITIES, LLC	0.03%	32.13K	27.08K	32.13K	+100.00%
Sep 30, 2025	MARINER, LLC	0.03%	25K	21.07K	0	0
Sep 30, 2025	LPL FINANCIAL LLC	0.03%	31K	26.12K	0	0
Sep 30, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.06%	56.08K	47.26K	0	0
Sep 30, 2025	NORTHERN TRUST CORP	0.07%	66.61K	56.13K	0	0
Sep 30, 2025	XTX TOPCO LTD	0.08%	76.05K	64.08K	41.32K	+119.02%
Jun 30, 2025	APTUS CAPITAL ADVISORS, LLC	0.03%	25K	17K	-21K	-45.65%
Jun 30, 2025	JPMORGAN CHASE & CO	0%	0	-	-62	-100.00%
Jun 30, 2025	PINNACLE FINANCIAL GROUP, LLC / IL	0.01%	10K	6.8K	0	0
Jun 30, 2025	PRIVATE WEALTH MANAGEMENT GROUP, LLC	0%	310	211	0	0
Jun 30, 2025	MILLENNIUM MANAGEMENT LLC	0%	0	-	-51.11K	-100.00%
Jun 30, 2025	STEWARD PARTNERS INVESTMENT ADVISORY, LLC	0%	0	-	-20K	-100.00%
Jun 30, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	0%	0	-	-40K	-100.00%
Jun 30, 2025	SCIENTECH RESEARCH LLC	0%	0	-	-42.55K	-100.00%
Jun 30, 2025	DUNHILL FINANCIAL, LLC	0.01%	10.27K	6.99K	0	0
Jun 30, 2025	RAYMOND JAMES FINANCIAL INC	0.03%	18.76K	12.76K	-15.2K	-44.76%
Jun 30, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0.02%	15.41K	10.48K	15.41K	+100.00%
Jun 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.22%	164.2K	111.64K	-13.5K	-7.60%
Jun 30, 2025	AVANTAX PLANNING PARTNERS, INC.	0.19%	142.34K	96.78K	-8.06K	-5.36%
Jun 30, 2025	TWO SIGMA INVESTMENTS, LP	0.1%	78.03K	53.05K	-6.04K	-7.18%
Jun 30, 2025	NORTHERN TRUST CORP	0.09%	66.61K	45.29K	0	0
Jun 30, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.08%	56.08K	38.13K	-15K	-21.10%
Jun 30, 2025	STATE STREET CORP	0.06%	43.39K	29.5K	0	0
Jun 30, 2025	XTX TOPCO LTD	0.05%	34.72K	23.61K	34.72K	+100.00%
Jun 30, 2025	LPL FINANCIAL LLC	0.04%	31K	21.08K	31K	+100.00%
Jun 30, 2025	SEVENBRIDGE FINANCIAL GROUP, LLC	0.03%	25K	17.5K	-21K	-45.65%
Jun 30, 2025	MARINER, LLC	0.03%	25K	17K	0	0
Jun 30, 2025	GILEAD SCIENCES, INC.	12.19%	9.11M	6.19M	0	0
Jun 30, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	6.11%	4.57M	3.1M	0	0
Jun 30, 2025	MERCK & CO., INC.	1.99%	1.48M	1.01M	0	0
Jun 30, 2025	MORGAN STANLEY	1.93%	1.44M	982M	288.49K	+24.96%
Jun 30, 2025	VANGUARD GROUP INC	1.54%	1.15M	782.7K	15.31K	+1.35%
Jun 30, 2025	FEDERATION DES CAISSES DESJARDINS DU QUEBEC	0%	3.3K	2.24K	0	0
Jun 30, 2025	BLACKROCK, INC.	0%	2.04K	1.39K	-72.66K	-97.27%
Jun 30, 2025	TAKEDA PHARMACEUTICAL CO LTD	1.97%	1.48M	1M	0	0
Jun 30, 2025	GHISALLO CAPITAL MANAGEMENT LLC	1.78%	1.33M	906.31K	1.33M	+100.00%
Jun 30, 2025	AJU IB INVESTMENT CO., LTD.	0.89%	667.74K	454K	0	0
Jun 30, 2025	FMR LLC	0.69%	511.82K	347.99K	-372.22K	-42.10%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.49%	369.66K	251.36K	-9.36K	-2.47%
Jun 30, 2025	TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK	0.33%	249.64K	169.75K	0	0
Jun 30, 2025	UBS GROUP AG	0.32%	239.97K	163.18K	76.87K	+47.13%
Jun 30, 2025	SQUAREPOINT OPS LLC	0.32%	235.46K	160.09K	235.46K	+100.00%
Jun 30, 2025	BALYASNY ASSET MANAGEMENT L.P.	0.27%	198.86K	135.2K	-55.49K	-21.82%
Jun 30, 2025	INVESTORS ASSET MANAGEMENT OF GEORGIA INC /GA/ /ADV	0.01%	10K	6.8K	0	0
Jun 30, 2025	KEY FINANCIAL INC	0%	830	564	0	0
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0%	331	225	41	+14.14%
Mar 31, 2025	SEVENBRIDGE FINANCIAL GROUP, LLC	0.06%	46K	33.63K	5K	+12.20%
Mar 31, 2025	TWO SIGMA INVESTMENTS, LP	0.11%	84.07K	60.9K	73.24K	+676.68%
Mar 31, 2025	PINNACLE FINANCIAL GROUP, LLC / IL	0.01%	10K	7.24K	0	0
Mar 31, 2025	INVESTORS ASSET MANAGEMENT OF GEORGIA INC /GA/ /ADV	0.01%	10K	7.24K	10K	+100.00%
Mar 31, 2025	DUNHILL FINANCIAL, LLC	0.01%	10.27K	7.44K	10.27K	+100.00%
Mar 31, 2025	STEWARD PARTNERS INVESTMENT ADVISORY, LLC	0.03%	20K	14.49K	0	0
Mar 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0.24%	177.7K	128.73K	-118.92K	-40.09%
Mar 31, 2025	TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK	0.33%	249.64K	180.74K	0	0
Mar 31, 2025	AJU IB INVESTMENT CO., LTD.	0.89%	667.74K	483.71K	0	0
Mar 31, 2025	FMR LLC	1.18%	884.04K	640.4K	-511.82K	-36.67%
Mar 31, 2025	VANGUARD GROUP INC	1.52%	1.14M	822.26K	233.19K	+25.84%
Mar 31, 2025	MORGAN STANLEY	1.55%	1.16M	837.29K	154.48K	+15.43%
Mar 31, 2025	BALYASNY ASSET MANAGEMENT L.P.	0.34%	254.35K	184.25K	-88.88K	-25.90%
Mar 31, 2025	MARINER, LLC	0.03%	25K	18.11K	0	0
Mar 31, 2025	CITADEL ADVISORS LLC	0%	0	-	-40.32K	-100.00%
Mar 31, 2025	FIL LTD	0%	0	-	-218.71K	-100.00%
Mar 31, 2025	AVANTAX PLANNING PARTNERS, INC.	0.2%	150.4K	108.95K	150.4K	+100.00%
Mar 31, 2025	UBS GROUP AG	0.22%	163.1K	118.09K	-86.3K	-34.60%
Mar 31, 2025	JPMORGAN CHASE & CO	0%	62	45	-4	-6.06%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0%	290	210	25	+9.43%
Mar 31, 2025	PRIVATE WEALTH MANAGEMENT GROUP, LLC	0%	310	225	0	0
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.51%	379.02K	274.59K	20.59K	+5.75%
Mar 31, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	6.11%	4.57M	3.31M	0	0
Mar 31, 2025	GILEAD SCIENCES, INC.	12.19%	9.11M	6.6M	0	0
Mar 31, 2025	STATE STREET CORP	0.06%	43.39K	31.43K	0	0
Mar 31, 2025	RAYMOND JAMES FINANCIAL INC	0.05%	33.96K	24.6K	-16.13K	-32.19%
Mar 31, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.1%	71.08K	51.49K	0	0
Mar 31, 2025	XTX TOPCO LTD	0%	0	-	-12.87K	-100.00%
Mar 31, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	0%	0	-	-3M	-100.00%
Mar 31, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0%	0	-	-2.73K	-100.00%
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	0.07%	51.11K	37.02K	51.11K	+100.00%
Mar 31, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	0.05%	40K	28.98K	40K	+100.00%
Mar 31, 2025	NORTHERN TRUST CORP	0.09%	66.61K	48.25K	27.4K	+69.89%
Mar 31, 2025	BLACKROCK, INC.	0.1%	74.7K	54.11K	-1.39K	-1.82%
Mar 31, 2025	KEY FINANCIAL INC	0%	830	601	0	0
Mar 31, 2025	SCIENTECH RESEARCH LLC	0.06%	42.55K	30.82K	42.55K	+100.00%
Mar 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0%	0	-	-49.09K	-100.00%
Mar 31, 2025	FEDERATION DES CAISSES DESJARDINS DU QUEBEC	0%	3.3K	2.39K	0	0
Mar 31, 2025	APTUS CAPITAL ADVISORS, LLC	0.06%	46K	33.32K	5K	+12.20%
Mar 31, 2024	RIVERVEST VENTURE MANAGEMENT LLC	5.23%	1.44M	1.56M	0	0
Mar 31, 2024	OCTAGON CAPITAL ADVISORS LP	0%	0	-	-1.79M	-100.00%
Mar 31, 2024	VIRTU FINANCIAL LLC	0%	0	-	-10.76K	-100.00%
Mar 31, 2024	ARROWMARK COLORADO HOLDINGS LLC	0%	0	-	-83.37K	-100.00%
Mar 31, 2024	CITADEL ADVISORS LLC	0%	0	-	-51.42K	-100.00%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0%	0	-	-11	-100.00%
Mar 31, 2024	CULLEN/FROST BANKERS, INC.	0%	0	-	-100	-100.00%
Mar 31, 2024	QUBE RESEARCH & TECHNOLOGIES LTD	0%	4	4	0	0
Mar 31, 2024	WELLS FARGO & COMPANY/MN	0%	108	117	2	+1.89%
Mar 31, 2024	ROYAL BANK OF CANADA	0%	533	1K	533	+100.00%
Mar 31, 2024	KEY FINANCIAL INC	0%	830	896	0	0
Mar 31, 2024	JPMORGAN CHASE & CO	0.01%	2.74K	2.96K	-113	-3.96%
Mar 31, 2024	DUNHILL FINANCIAL, LLC	0.04%	10.27K	15.72K	0	0
Mar 31, 2024	TOWER RESEARCH CAPITAL LLC (TRC)	0.04%	11.15K	12.05K	-2.82K	-20.19%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.04%	11.93K	12.88K	0	0
Mar 31, 2024	STATE STREET CORP	0.06%	15.69K	16.95K	0	0
Mar 31, 2024	NORTHERN TRUST CORP	0.06%	17.8K	19.22K	0	0
Mar 31, 2024	FNY INVESTMENT ADVISERS, LLC	0.1%	27.5K	29K	27.5K	+100.00%
Mar 31, 2024	PRELUDE CAPITAL MANAGEMENT, LLC	0.11%	29.5K	31.86K	29.5K	+100.00%
Mar 31, 2024	PFG INVESTMENTS, LLC	0.11%	30K	32.4K	30K	+100.00%
Mar 31, 2024	SEVENBRIDGE FINANCIAL GROUP, LLC	0.11%	31K	36.58K	31K	+100.00%
Mar 31, 2024	BLACKROCK INC.	0.16%	45.36K	48.98K	-1.51K	-3.22%
Mar 31, 2024	MILLENNIUM MANAGEMENT LLC	0.25%	70.2K	75.81K	39.85K	+131.29%
Mar 31, 2024	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.26%	71.08K	76.77K	-84.4K	-54.28%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	0.31%	84.83K	91.65K	0	0
Mar 31, 2024	FIL LTD	0.79%	218.71K	236.2K	0	0
Mar 31, 2024	MORGAN STANLEY	0.81%	221.91K	239.66K	94.64K	+74.36%
Mar 31, 2024	RENAISSANCE TECHNOLOGIES LLC	0.91%	249.45K	269K	39.75K	+18.95%
Mar 31, 2024	LAURION CAPITAL MANAGEMENT LP	0%	0	-	-116.85K	-100.00%
Mar 31, 2024	ARTAL GROUP S.A.	0%	0	-	-450K	-100.00%
Mar 31, 2024	UBS GROUP AG	0%	201	217	0	0
Mar 31, 2024	BALYASNY ASSET MANAGEMENT L.P.	1.23%	338.54K	365.63K	338.54K	+100.00%
Mar 31, 2024	VANGUARD GROUP INC	3.28%	902.53K	974.73K	0	0
Mar 31, 2024	ATLAS VENTURE LIFE SCIENCE ADVISORS, LLC	3.6%	992.91K	1.07M	-1.77M	-64.02%
Mar 31, 2024	ROCK SPRINGS CAPITAL MANAGEMENT LP	5.23%	1.44M	1.56M	0	0
Mar 31, 2024	FMR LLC	6.92%	1.91M	2.06M	0	0
Mar 31, 2024	SUMMIT TRAIL ADVISORS, LLC	0.06%	16K	17.28K	16K	+100.00%
Mar 31, 2024	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	10.18%	2.81M	3.03M	0	0
Dec 31, 2023	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	10.19%	2.81M	1.54M	0	0
Dec 31, 2023	SOLEUS CAPITAL MANAGEMENT, L.P.	0%	0	-	-226.94K	-100.00%
Dec 31, 2023	HARVARD MANAGEMENT CO INC	0%	0	-	-416.06K	-100.00%
Dec 31, 2023	ROYAL BANK OF CANADA	0%	0	-	-350	-100.00%
Dec 31, 2023	DIMENSIONAL FUND ADVISORS LP	0%	0	-	-26.45K	-100.00%
Dec 31, 2023	QUBE RESEARCH & TECHNOLOGIES LTD	0%	4	2	0	0
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0%	11	6	-226.71K	-100.00%
Dec 31, 2023	CULLEN/FROST BANKERS, INC.	0%	100	55	0	0
Dec 31, 2023	WELLS FARGO & COMPANY/MN	0%	106	58	6	+6.00%
Dec 31, 2023	UBS GROUP AG	0%	201	111	0	0
Dec 31, 2023	KEY FINANCIAL INC	0%	830	456	0	0
Dec 31, 2023	JPMORGAN CHASE & CO	0.01%	2.86K	1.57K	135	+4.96%
Dec 31, 2023		0.04%	10.27K	5.65K	10.27K	+100.00%
Dec 31, 2023	VIRTU FINANCIAL LLC	0.04%	10.76K	6K	10.76K	+100.00%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.04%	11.93K	6.56K	0	0
Dec 31, 2023	TOWER RESEARCH CAPITAL LLC (TRC)	0.05%	13.98K	7.69K	10.09K	+259.99%
Dec 31, 2023	STATE STREET CORP	0.06%	15.69K	8.63K	0	0
Dec 31, 2023	NORTHERN TRUST CORP	0.06%	17.8K	9.79K	0	0
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	0.11%	30.35K	16.69K	30.35K	+100.00%
Dec 31, 2023	BLACKROCK INC.	0.17%	46.86K	25.77K	-522	-1.10%
Dec 31, 2023	CITADEL ADVISORS LLC	0.19%	51.42K	28.28K	51.42K	+100.00%
Dec 31, 2023	ARROWMARK COLORADO HOLDINGS LLC	0.3%	83.37K	45.86K	83.37K	+100.00%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	0.31%	84.83K	46.67K	0	0
Dec 31, 2023	LAURION CAPITAL MANAGEMENT LP	0.42%	116.85K	64.27K	-22.41K	-16.09%
Dec 31, 2023	MORGAN STANLEY	0.46%	127.27K	70K	101K	+384.54%
Dec 31, 2023	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.56%	155.48K	85.52K	45K	+40.73%
Dec 31, 2023	RENAISSANCE TECHNOLOGIES LLC	0.76%	209.7K	115K	189K	+913.04%
Dec 31, 2023	FIL LTD	0.79%	218.71K	120.29K	0	0
Dec 31, 2023	TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK	0.91%	249.64K	137.3K	0	0
Dec 31, 2023	ARTAL GROUP S.A.	1.63%	450K	248K	0	0
Dec 31, 2023	VANGUARD GROUP INC	3.28%	902.53K	496.39K	12.18K	+1.37%
Dec 31, 2023	ROCK SPRINGS CAPITAL MANAGEMENT LP	5.23%	1.44M	792.42K	0	0
Dec 31, 2023	RIVERVEST VENTURE MANAGEMENT LLC	5.24%	1.44M	792.79K	0	0
Dec 31, 2023	OCTAGON CAPITAL ADVISORS LP	6.49%	1.79M	981.75K	-533.5K	-23.01%
Dec 31, 2023	FMR LLC	6.93%	1.91M	1.05M	0	0
Dec 31, 2023	ATLAS VENTURE LIFE SCIENCE ADVISORS, LLC	10.03%	2.76M	1.52M	0	0

Insiders

Among the XLO insiders holding of 28.58% of the stake in company, GILEAD SCIENCES, INC., 10 percent owner, holds the largest shares of 40.38M. BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC, 10 percent owner, is the second largest XLO insider with ownership of 2.8M shares. SV7 IMPACT MEDICINE FUND LP, 10 percent owner, stands third with possession of 1.61M shares of that stake.

Insiders	Designation	Shares Held
GILEAD SCIENCES, INC.	10 percent owner	40.38M
BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	10 percent owner	2.8M
SV7 IMPACT MEDICINE FUND LP	10 percent owner	1.61M
RIVERVEST VENTURE FUND IV, L.P.	10 percent owner	1.44M
ROCK SPRINGS CAPITAL MANAGEMENT LP	10 percent owner	1.26M
FLYNN JAMES E	10 percent owner	1.14M
BAY CITY CAPITAL LLC	10 percent owner	1.13M
ATLAS VENTURE FUND XI, L.P.	10 percent owner	734.55K
RUSSO RENE	PRESIDENT AND CEO	281.17K
FRANKENFIELD CHRISTOPHER JAMES	Chief Financial Officer	24.77K
SHANNON JAMES SAMUEL	director	10K
BRENNAN KEVIN M.	SVP, FINANCE AND ACCOUNTING	6.37K

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Mar 26, 2026	SHANNON JAMES SAMUEL	PURCHASE	8.79	5K	43.95K	10K
Feb 13, 2026	GILEAD SCIENCES, INC.	PURCHASE	0.00	3.74M	373.9	40.38M
Jan 02, 2026	BRENNAN KEVIN M.	SALE	0.64	1.83K	1.17K	6.37K
Jan 02, 2026	FRANKENFIELD CHRISTOPHER JAMES	SALE	0.64	7.03K	4.52K	24.77K
Jun 17, 2025	SHANNON JAMES SAMUEL	PURCHASE	0.69	25K	17.22K	70K
Jun 16, 2025	SHANNON JAMES SAMUEL	PURCHASE	0.69	45K	30.87K	45K
Jun 16, 2025	RUSSO RENE	PURCHASE	0.68	36.29K	24.68K	281.17K
Jun 05, 2025	GILEAD SCIENCES, INC.	PURCHASE	0.75	13.34M	10M	13.34M
Jan 02, 2025	FRANKENFIELD CHRISTOPHER JAMES	SALE	0.98	6.95K	6.84K	12.42K
Jan 02, 2025	BRENNAN KEVIN M.	SALE	0.98	1.8K	1.77K	3.2K
Dec 18, 2024	GILEAD SCIENCES, INC.	PURCHASE	1.04	1.76M	1.83M	9.11M
Apr 02, 2024	GILEAD SCIENCES, INC.	PURCHASE	0.00	3.88M	388.25	3.88M
Feb 08, 2024	ATLAS VENTURE FUND XI, L.P.	SALE	0.64	267	170.88	734.55K
Jan 12, 2024	ATLAS VENTURE FUND XI, L.P.	SALE	0.83	560	464.8	734.81K
Jan 11, 2024	ATLAS VENTURE FUND XI, L.P.	SALE	0.87	569	495.03	735.37K
Dec 10, 2021	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	PURCHASE	9.56	21.81K	208.56K	2.8M
Dec 09, 2021	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	PURCHASE	9.84	4.01K	39.49K	2.78M
Dec 08, 2021	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	PURCHASE	9.62	13.46K	129.47K	2.78M
Oct 26, 2021	ROCK SPRINGS CAPITAL MANAGEMENT LP	PURCHASE	16.00	500K	8M	1.26M
Oct 26, 2021	ATLAS VENTURE FUND XI, L.P.	PURCHASE	16.00	187.5K	3M	735.94K
Oct 26, 2021	SV7 IMPACT MEDICINE FUND LP	PURCHASE	16.00	312.5K	5M	1.61M
Oct 26, 2021	FLYNN JAMES E	PURCHASE	16.00	387.5K	6.2M	1.14M
Oct 26, 2021	RIVERVEST VENTURE FUND IV, L.P.	PURCHASE	16.00	250K	4M	1.44M
Oct 26, 2021	BAY CITY CAPITAL LLC	PURCHASE	16.00	312.5K	5M	1.13M

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE3.74M2

SALES00

NET SHARES3.74M2

SHARES HELD40.39M2

% NET SHARES-90.73%0%

Frequently Asked Questions