How many institutions own XFOR stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own XFOR shares is 59, representing 30.98% of the company's common stock.

Who are the major shareholders selling X4 Pharmaceuticals, Inc. stock?

PALE FIRE CAPITAL SE, in the last quarter, reduced its stake in XFOR by -7.33% restricting it's holding to 167.59 thousand shares of worth nearly $670.36K. BNP PARIBAS ARBITRAGE, SNC also lessened -7.76% of the XFOR shares from its portfolio, reducing its holding to 511 shares of worth $2.04K. SBI SECURITIES CO., LTD. also shunned XFOR shares holding by -76.85% last quarter which brought its holding to 50 shares worth $200.00.

Investors who are buying XFOR stock?

As per its latest 13F filing, SILVERARC CAPITAL MANAGEMENT, LLC increased its stake in XFOR by 100% in the last quarter. The institutional holder raised its holding to 357.39 thousand shares having worth more than $1.43M. JANE STREET GROUP, LLC also added 100% more shares of XFOR to its portfolio, raising its holding to 91.41 thousand shares of worth $365.65K. OMERS ADMINISTRATION CORP also increased its XFOR shares holding by 100% which brought its holding to 109.2 thousand shares worth $436.80K.

XFOR's major insiders: who are they?

The insider with the most stakes in XFOR is SVLSF V, LLC , 10 percent owner at the company. Additionally, XFOR stock is highly held by President and CEO Ragan Paula and director Nessi Claudio among others.

Did an insider recently sell XFOR stock?

Company executives, directors, and other insiders own 1.15% percent of X4 Pharmaceuticals, Inc.'s stock. Within the last six months, there have been 0 transaction(s) in which XFOR insiders have sold stock, totaling 0 shares. Insiders that have sold shares include ARBET-ENGELS CHRISTOPHE, RAGAN PAULA, and MOSTAFA ADAM S..

Which insider recently purchased XFOR stock?

There have been 1 transaction(s) during the past 6-months in which X4 Pharmaceuticals, Inc. insiders have bought stock, totalling 86206 shares

How much of XFOR does insiders own?

Around 376.09K X4 Pharmaceuticals, Inc. shares are held by insiders, which represents about 1.15% of XFOR stock.

Who is the insider with the largest stake?

XFOR 10 percent owner, SVLSF V, LLC holds the largest portfolio of the company's shares. XFOR shares owned by SVLSF total nearly 1.85 million.

Which institution holds the most shares in XFOR?

SILVERARC CAPITAL MANAGEMENT, LLC is the largest institutional owner in XFOR which holds 357.39 thousand shares worth $1.43M or 4.82% of the total XFOR shares outstanding followed by JANE STREET GROUP, LLC with ownership of 91.41 thousand shares representing 1.23% of the XFOR ownership. OMERS ADMINISTRATION CORP is the third largest stakeholder with 109.2 thousand shares or 1.47% of the ownership worth more than $436.80K.

Is X4 Pharmaceuticals, Inc. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the XFOR is concerned, it is a stock which is not optionable.

Is there a short position on XFOR's shares?

Number of XFOR shares short is 1.55M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding XFOR shares are there?

As of today, 22.45M shares of XFOR are outstanding.

Is there many float in XFOR stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, XFOR has 8.16M shares in float.

XFOR short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for XFOR is 0.17.

X4 Pharmaceuticals (XFOR) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableNo

Short Percent Of Outstanding Shares6.93

Short Percent Of Float6.95

Shares Outstanding22.45M

Shares Float8.16M

Shares Short1.55M

Short Ratio0.17

6.95%

Short % of Float

6.93%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

1.15% Percentage of Shares held by All Insiders

30.98% Percentage of Shares held by All Institutions

31.34% Percentage of Float held by Institutions

Number of Institutions Holding Shares

Institutional Ownership

About 30.98% of XFOR shares are held by financial institutions. SILVERARC CAPITAL MANAGEMENT, LLC is the top corporate investor, holding 357.39K shares valued at $1.43M. A 4.82% stake in X4 Pharmaceuticals, Inc. is owned by the company. JANE STREET GROUP, LLC owns 91.41K shares valued at $365.65K, which translates its holding of 1.23% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Dec 31, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	4.82%	357.39K	1.43M	357.39K	+100.00%
Dec 31, 2025	JANE STREET GROUP, LLC	1.23%	91.41K	365.65K	91.41K	+100.00%
Dec 31, 2025	OMERS ADMINISTRATION CORP	1.47%	109.2K	436.8K	109.2K	+100.00%
Dec 31, 2025	PALUMBO WEALTH MANAGEMENT LLC	1.53%	113.36K	453.43K	18.03K	+18.91%
Dec 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.3%	22.14K	88.54K	22.14K	+100.00%
Dec 31, 2025	CITADEL ADVISORS LLC	1.74%	128.68K	514.7K	128.68K	+100.00%
Dec 31, 2025	AFFINITY ASSET ADVISORS, LLC	1.96%	145K	580K	145K	+100.00%
Dec 31, 2025	VIRTU FINANCIAL LLC	0.3%	22.49K	90K	22.49K	+100.00%
Dec 31, 2025	MAN GROUP PLC	0.33%	24.19K	96.75K	24.19K	+100.00%
Dec 31, 2025	SUSQUEHANNA PORTFOLIO STRATEGIES, LLC	0.58%	43.26K	173.04K	43.26K	+100.00%
Dec 31, 2025	BALYASNY ASSET MANAGEMENT L.P.	0.87%	64.51K	258.02K	64.51K	+100.00%
Dec 31, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.91%	67.75K	270.99K	67.75K	+100.00%
Dec 31, 2025	EXODUSPOINT CAPITAL MANAGEMENT, LP	1.07%	79.07K	316.29K	79.07K	+100.00%
Dec 31, 2025	PALE FIRE CAPITAL SE	2.26%	167.59K	670.36K	-13.26K	-7.33%
Dec 31, 2025	NORTHERN TRUST CORP	2.4%	178.24K	712.94K	178.24K	+100.00%
Dec 31, 2025	POINT72 ASSET MANAGEMENT, L.P.	10.9%	808.15K	3.23M	786.49K	+3,630.06%
Dec 31, 2025	GOLDMAN SACHS GROUP INC	11.22%	831.89K	3.33M	831.89K	+100.00%
Dec 31, 2025	STEMPOINT CAPITAL LP	12.12%	898.47K	3.59M	343.05K	+61.77%
Dec 31, 2025	WOODLINE PARTNERS LP	13.5%	1M	4M	1M	+100.00%
Dec 31, 2025	SAMSARA BIOCAPITAL, LLC	26.44%	1.96M	7.84M	1.96M	+100.00%
Dec 31, 2025	BVF INC/IL	30.13%	2.23M	8.93M	0	0
Dec 31, 2025	BLACKSTONE INC.	36.18%	2.68M	10.73M	2.68M	+100.00%
Dec 31, 2025	BRAIDWELL LP	45.45%	3.37M	13.48M	3.37M	+100.00%
Dec 31, 2025	SATURN V CAPITAL MANAGEMENT LLC	78.25%	5.8M	23.2M	5.8M	+100.00%
Dec 31, 2025	PERCEPTIVE ADVISORS LLC	85.18%	6.31M	25.26M	6.31M	+100.00%
Dec 31, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	107.48%	7.97M	31.87M	5.53M	+226.99%
Dec 31, 2025	FMR LLC	114.65%	8.5M	34M	8.5M	+100.00%
Dec 31, 2025	VANGUARD GROUP INC	46.18%	3.42M	13.69M	3.01M	+734.05%
Dec 31, 2025	DEEP TRACK CAPITAL, LP	67.63%	5.01M	20.05M	3.89M	+346.66%
Dec 31, 2025	MORGAN STANLEY	110.72%	8.21M	32.83M	8.2M	+220,072.08%
Dec 31, 2025	EMPERY ASSET MANAGEMENT, LP	120.75%	8.95M	35.8B	8.95M	+100.00%
Dec 31, 2025	NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO	0%	5	20	5	+100.00%
Dec 31, 2025	HIGHMARK WEALTH MANAGEMENT LLC	0%	6	24	0	0
Dec 31, 2025	JONES FINANCIAL COMPANIES LLLP	0%	38	152	0	0
Dec 31, 2025	RONALD BLUE TRUST, INC.	0%	284	1.14K	0	0
Dec 31, 2025	FARTHER FINANCE ADVISORS, LLC	0%	331	1.32K	331	+100.00%
Dec 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.01%	511	2.04K	-43	-7.76%
Dec 31, 2025	ALLWORTH FINANCIAL LP	0.01%	715	2.86K	715	+100.00%
Dec 31, 2025	CIBC PRIVATE WEALTH GROUP, LLC	0.03%	2.17K	8.66K	0	0
Dec 31, 2025	SIGNATUREFD, LLC	0.04%	2.75K	11.02K	2.75K	+100.00%
Dec 31, 2025	GROUP ONE TRADING, L.P.	0.05%	4K	15.99K	0	0
Dec 31, 2025	SBI SECURITIES CO., LTD.	0%	50	200	-166	-76.85%
Dec 31, 2025	FORTITUDE FAMILY OFFICE, LLC	0%	137	548	137	+100.00%
Dec 31, 2025	BLEICHROEDER LP	0.01%	595	2.38K	0	0
Dec 31, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0.14%	10.45K	41.78M	-233	-2.18%
Dec 31, 2025	STONEPINE CAPITAL MANAGEMENT, LLC	8.01%	593.57K	2.37M	-462.77K	-43.81%
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	12.69%	940.45K	3.76M	860.79K	+1,080.61%
Dec 31, 2025	BLACKROCK, INC.	16.55%	1.23M	4.91M	1.16M	+1,880.83%
Dec 31, 2025	SIREN, L.L.C.	20.23%	1.5M	6M	1.5M	+100.00%
Dec 31, 2025	NANTAHALA CAPITAL MANAGEMENT, LLC	33.04%	2.45M	9.8M	221.12K	+9.92%
Dec 31, 2025	ROSALIND ADVISORS, INC.	35.15%	2.61M	10.42M	1.06M	+68.71%
Dec 31, 2025	TD WATERHOUSE CANADA INC.	0%	0	-	-1.5K	-100.00%
Dec 31, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0%	0	-	-343.96K	-100.00%
Dec 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0%	0	-	-19.18K	-100.00%
Dec 31, 2025	ROYAL BANK OF CANADA	0%	0	-	-2.53K	-100.00%
Dec 31, 2025	KINGDON CAPITAL MANAGEMENT, L.L.C.	0%	0	-	-933.33K	-100.00%
Dec 31, 2025	PNC FINANCIAL SERVICES GROUP, INC.	0.02%	1.76K	7.04K	0	0
Dec 31, 2025	STATE STREET CORP	2.67%	198.23K	792.94K	159.5K	+411.78%
Dec 31, 2025	UBS GROUP AG	0.06%	4.13K	16.52K	-155.71K	-97.42%
Dec 31, 2025	JPMORGAN CHASE & CO	0.06%	4.58K	18.32K	4.55K	+13,781.82%
Dec 31, 2025		34.69%	2.57M	10.29B	2.57M	+100.00%
Dec 31, 2025	SQUAREPOINT OPS LLC	0.17%	12.52K	50.07K	12.52K	+100.00%
Dec 31, 2025	CAXTON CORP	0.21%	15.56K	62.23K	15.56K	+100.00%
Dec 31, 2025	TWO SIGMA INVESTMENTS, LP	0.23%	17.25K	68.98K	3.38K	+24.36%
Dec 31, 2025	STIFEL FINANCIAL CORP	0.28%	20.5K	81.98K	20.5K	+100.00%
Dec 31, 2025	LIGHTHOUSE INVESTMENT PARTNERS, LLC	0.3%	22.2K	88.8K	22.2K	+100.00%
Dec 31, 2025	JEFFERIES FINANCIAL GROUP INC.	0.35%	26.12K	104.47K	26.12K	+100.00%
Dec 31, 2025	HUDSON BAY CAPITAL MANAGEMENT LP	0.43%	32.24K	128.96K	32.24K	+100.00%
Dec 31, 2025	CITIGROUP INC	0.44%	32.33K	129.33K	32.3K	+100,937.50%
Dec 31, 2025	BANK OF AMERICA CORP /DE/	0.48%	35.76K	143.04K	16.46K	+85.25%
Dec 31, 2025	MILLENNIUM MANAGEMENT LLC	0.76%	55.98K	223.91K	-8.82K	-13.61%
Dec 31, 2025	BARCLAYS PLC	0.78%	57.5K	230K	57.5K	+100.00%
Dec 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.9%	66.79K	267.15K	66.79K	+100.00%
Dec 31, 2025	MARSHALL WACE, LLP	1.09%	80.46K	321.82K	80.46K	+100.00%
Sep 30, 2025	SQUAREPOINT OPS LLC	0%	0	-	-38.98K	-100.00%
Sep 30, 2025	JANE STREET GROUP, LLC	0%	0	-	-97.34K	-100.00%
Sep 30, 2025	SRS CAPITAL ADVISORS, INC.	0%	0	-	-1.12K	-100.00%
Sep 30, 2025	VIRTU FINANCIAL LLC	0%	0	-	-12.59K	-100.00%
Sep 30, 2025	JPMORGAN CHASE & CO	0%	33	113	0	0
Sep 30, 2025	JONES FINANCIAL COMPANIES LLLP	0%	38	131	0	0
Sep 30, 2025	SBI SECURITIES CO., LTD.	0%	216	739	0	0
Sep 30, 2025	RONALD BLUE TRUST, INC.	0%	284	971	0	0
Sep 30, 2025	CIBC PRIVATE WEALTH GROUP, LLC	0.03%	2.17K	7.41K	0	0
Sep 30, 2025	ROYAL BANK OF CANADA	0.03%	2.53K	9K	-552	-17.89%
Sep 30, 2025	POINT72 ASIA (SINGAPORE) PTE. LTD.	0.04%	2.91K	9.97K	2.91K	+100.00%
Sep 30, 2025	BLEICHROEDER LP	0.01%	595	2.04K	0	0
Sep 30, 2025	MORGAN STANLEY	0.05%	3.73K	12.75K	-7.2K	-65.87%
Sep 30, 2025	GROUP ONE TRADING, L.P.	0.05%	4K	13.67K	0	0
Sep 30, 2025	TWO SIGMA INVESTMENTS, LP	0.19%	13.87K	47.43K	13.87K	+100.00%
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.26%	19.18K	65.59K	1.81K	+10.43%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.26%	19.3K	66.02K	-61.01K	-75.96%
Sep 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.29%	21.67K	74.1K	-1	0.00%
Sep 30, 2025	STATE STREET CORP	0.52%	38.73K	132.47K	23.2K	+149.35%
Sep 30, 2025	BLACKROCK, INC.	0.84%	61.93K	211.81K	-117.29K	-65.44%
Sep 30, 2025	MILLENNIUM MANAGEMENT LLC	0.87%	64.8K	221.6K	-13.27K	-16.99%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.07%	79.66K	272.47K	30.51K	+62.08%
Sep 30, 2025	PALUMBO WEALTH MANAGEMENT LLC	1.29%	95.33K	326.02K	95.33K	+100.00%
Sep 30, 2025	UBS GROUP AG	2.16%	159.84K	546.64K	49.88K	+45.36%
Sep 30, 2025	PALE FIRE CAPITAL SE	2.44%	180.85K	618.51K	120.8K	+201.16%
Sep 30, 2025	BOOTHBAY FUND MANAGEMENT, LLC	4.64%	343.96K	1.18M	343.96K	+100.00%
Sep 30, 2025	VANGUARD GROUP INC	5.54%	410.49K	1.4M	178.59K	+77.02%
Sep 30, 2025	STEMPOINT CAPITAL LP	7.49%	555.41K	1.9M	555.41K	+100.00%
Sep 30, 2025	KINGDON CAPITAL MANAGEMENT, L.L.C.	12.59%	933.33K	3.19M	700K	+300.00%
Sep 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0%	0	-	-34.82K	-100.00%
Sep 30, 2025	GSA CAPITAL PARTNERS LLP	0%	0	-	-132.72K	-100.00%
Sep 30, 2025	RAYMOND JAMES FINANCIAL INC	0%	0	-	-66	-100.00%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0%	0	-	-348	-100.00%
Sep 30, 2025	HIGHMARK WEALTH MANAGEMENT LLC	0%	6	21	0	0
Sep 30, 2025	UBS OCONNOR LLC	0%	0	-	-80K	-100.00%
Sep 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0.01%	729	2.49K	-9K	-92.51%
Sep 30, 2025	TD WATERHOUSE CANADA INC.	0.02%	1.5K	5.37K	0	0
Sep 30, 2025	TRUE WEALTH DESIGN, LLC	0%	0	-	-3	-100.00%
Sep 30, 2025	EVERSOURCE WEALTH ADVISORS, LLC	0%	0	-	-23	-100.00%
Sep 30, 2025	CWM, LLC	0%	0	-	-2.41K	-100.00%
Sep 30, 2025	CITIGROUP INC	0%	32	109	-730	-95.80%
Sep 30, 2025	ROCKEFELLER CAPITAL MANAGEMENT L.P.	0%	33	113	33	+100.00%
Sep 30, 2025	NEWEDGE ADVISORS, LLC	0%	33	113	0	0
Sep 30, 2025	STONEPINE CAPITAL MANAGEMENT, LLC	14.25%	1.06M	3.61M	1.06M	+100.00%
Sep 30, 2025	DEEP TRACK CAPITAL, LP	15.14%	1.12M	3.84M	1.12M	+100.00%
Sep 30, 2025	ROSALIND ADVISORS, INC.	20.84%	1.54M	5.28M	1.54M	+100.00%
Sep 30, 2025	NANTAHALA CAPITAL MANAGEMENT, LLC	30.06%	2.23M	7.62M	2.23M	+100.00%
Sep 30, 2025	BVF INC/IL	30.13%	2.23M	7.64M	2.23M	+100.00%
Sep 30, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	32.87%	2.44M	8.33M	1.87M	+332.13%
Sep 30, 2025	FMR LLC	0%	0	-	-1.7K	-100.00%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.01%	554	1.9K	-82	-12.89%
Sep 30, 2025	FEDERATED HERMES, INC.	0%	0	-	-149	-100.00%
Sep 30, 2025	NISA INVESTMENT ADVISORS, LLC	0%	0	-	-139	-100.00%
Sep 30, 2025	CLEARSTEAD ADVISORS, LLC	0%	0	-	-64	-100.00%
Sep 30, 2025	PNC FINANCIAL SERVICES GROUP, INC.	0.02%	1.76K	6.02K	-34	-1.90%
Sep 30, 2025	HRT FINANCIAL LP	0%	0	-	-10.55K	-100.00%
Sep 30, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0.14%	10.68K	36.52K	5.48K	+105.25%
Jun 30, 2025	JPMORGAN CHASE & CO	0%	0	-	-165.44K	-100.00%
Jun 30, 2025	AQR CAPITAL MANAGEMENT LLC	0%	26.38K	50.13M	26.38K	+100.00%
Jun 30, 2025	NORTHERN TRUST CORP	0%	0	-	-1.25M	-100.00%
Jun 30, 2025	STATE STREET CORP	0.21%	15.53K	29.52K	15.53K	+100.00%
Jun 30, 2025	BARCLAYS PLC	0%	0	-	-185.08K	-100.00%
Jun 30, 2025	COMMONWEALTH EQUITY SERVICES, LLC	0%	0	-	-25.25K	-100.00%
Jun 30, 2025	STIFEL FINANCIAL CORP	0%	0	-	-75.55K	-100.00%
Jun 30, 2025	LEGAL & GENERAL GROUP PLC	0%	0	-	-18.61K	-100.00%
Jun 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0%	0	-	-51.64K	-100.00%
Jun 30, 2025	AMERIPRISE FINANCIAL INC	0%	0	-	-22.24K	-100.00%
Jun 30, 2025	HSBC HOLDINGS PLC	0%	0	-	-19.93K	-100.00%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0%	0	-	-481.53K	-100.00%
Jun 30, 2025	MORGAN STANLEY	0%	10.92K	20.76M	10.92K	+100.00%
Jun 30, 2025	AXA S.A.	0%	0	-	-691.12K	-100.00%
Jun 30, 2025	AMALGAMATED BANK	0%	0	-	-4.15K	-100.00%
Jun 30, 2025	RAYMOND JAMES FINANCIAL INC	0%	66	125	66	+100.00%
Jun 30, 2025	JANE STREET GROUP, LLC	1.31%	97.34K	184.95K	97.34K	+100.00%
Jun 30, 2025	CANTOR FITZGERALD, L. P.	0%	0	-	-40.25K	-100.00%
Jun 30, 2025	ORBIMED ADVISORS LLC	0%	0	-	-6.78M	-100.00%
Jun 30, 2025	AMERITAS INVESTMENT PARTNERS, INC.	0%	0	-	-10.17K	-100.00%
Jun 30, 2025	CIBC WORLD MARKETS CORP	0%	0	-	-37.87K	-100.00%
Jun 30, 2025	VOYA INVESTMENT MANAGEMENT LLC	0%	0	-	-59.32K	-100.00%
Jun 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0%	0	-	-57.96K	-100.00%
Jun 30, 2025	RHUMBLINE ADVISERS	0%	0	-	-188.42K	-100.00%
Jun 30, 2025	PRINCIPAL FINANCIAL GROUP INC	0%	0	-	-13.72K	-100.00%
Jun 30, 2025	PALE FIRE CAPITAL SE	0.81%	60.05K	114.1K	60.05K	+100.00%
Jun 30, 2025	BLACKROCK, INC.	0%	179.23K	340.53K	179.23K	+100.00%
Jun 30, 2025	NEWEDGE ADVISORS, LLC	0%	33	63	33	+100.00%
Jun 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.29%	21.67K	41.17K	21.67K	+100.00%
Jun 30, 2025	SCHONFELD STRATEGIC ADVISORS LLC	0.15%	11.26K	21.4K	11.26K	+100.00%
Jun 30, 2025	NEA MANAGEMENT COMPANY, LLC	0.01%	499.56K	949.16K	-14.49M	-96.67%
Jun 30, 2025	INVESCO LTD.	0%	0	-	-58.19K	-100.00%
Jun 30, 2025	DEUTSCHE BANK AG\	0%	0	-	-267.63K	-100.00%
Jun 30, 2025	GROUP ONE TRADING, L.P.	0.05%	4K	7.6K	4K	+100.00%
Jun 30, 2025	FMR LLC	0.02%	1.7K	3.22K	1.7K	+100.00%
Jun 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.01%	636	1.21K	636	+100.00%
Jun 30, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	0.01%	563.86K	1.07M	563.86K	+100.00%
Jun 30, 2025	WELLS FARGO & COMPANY/MN	0%	348	661	348	+100.00%
Jun 30, 2025	KINGDON CAPITAL MANAGEMENT, L.L.C.	0%	233.33K	443.33K	233.33K	+100.00%
Jun 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0%	17.37K	33K	17.37K	+100.00%
Jun 30, 2025	VIRTU FINANCIAL LLC	0%	12.59K	24K	12.59K	+100.00%
Jun 30, 2025	BLEICHROEDER LP	0%	595	1.13K	595	+100.00%
Jun 30, 2025	VANGUARD GROUP INC	0%	231.89K	440.6K	231.89K	+100.00%
Jun 30, 2025	UBS OCONNOR LLC	0%	80K	152K	80K	+100.00%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0%	49.15K	93.4K	49.15K	+100.00%
Jun 30, 2025	SRS CAPITAL ADVISORS, INC.	0%	1.12K	2.13K	1.12K	+100.00%
Jun 30, 2025	PNC FINANCIAL SERVICES GROUP, INC.	0%	1.79K	3.41K	1.79K	+100.00%
Jun 30, 2025	HRT FINANCIAL LP	0%	10.55K	20K	10.55K	+100.00%
Jun 30, 2025	ROYAL BANK OF CANADA	0.04%	3.09K	6K	3.09K	+100.00%
Jun 30, 2025	CIBC PRIVATE WEALTH GROUP, LLC	0%	2.17K	4.12K	2.17K	+100.00%
Jun 30, 2025	TD WATERHOUSE CANADA INC.	0%	1.5K	2.81K	1.5K	+100.00%
Jun 30, 2025	RONALD BLUE TRUST, INC.	0%	284	540	284	+100.00%
Jun 30, 2025		0%	216	410	216	+100.00%
Jun 30, 2025	TRUE WEALTH DESIGN, LLC	0%	3	6	3	+100.00%
Jun 30, 2025	ACORN CAPITAL ADVISORS, LLC	0%	153.73K	292.09K	-7.16M	-97.90%
Jun 30, 2025	CITIGROUP INC	0%	762	1.45K	762	+100.00%
Jun 30, 2025	SBI SECURITIES CO., LTD.	0%	216	410	216	+100.00%
Jun 30, 2025	FEDERATED HERMES, INC.	0%	149	283	149	+100.00%
Jun 30, 2025	NISA INVESTMENT ADVISORS, LLC	0%	139	264	139	+100.00%
Jun 30, 2025	CLEARSTEAD ADVISORS, LLC	0%	64	122	64	+100.00%
Jun 30, 2025	JONES FINANCIAL COMPANIES LLLP	0%	38	70	38	+100.00%
Jun 30, 2025	EVERSOURCE WEALTH ADVISORS, LLC	0%	23	44	-7	-23.33%
Jun 30, 2025	HIGHMARK WEALTH MANAGEMENT LLC	0%	6	11	6	+100.00%
Jun 30, 2025	UBS GROUP AG	1.48%	109.96K	208.92K	109.96K	+100.00%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	1.08%	80.32K	152.6K	80.32K	+100.00%
Jun 30, 2025	SQUAREPOINT OPS LLC	0.53%	38.98K	74.07K	38.98K	+100.00%
Jun 30, 2025	MILLENNIUM MANAGEMENT LLC	1.05%	78.06K	148.32K	78.06K	+100.00%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0%	18.86K	35.84M	18.86K	+100.00%
Jun 30, 2025	CWM, LLC	0%	2.41K	5K	2.41K	+100.00%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.47%	34.82K	66.16K	34.82K	+100.00%
Jun 30, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0.07%	5.2K	9.89K	5.2K	+100.00%
Jun 30, 2025	GSA CAPITAL PARTNERS LLP	0%	132.72K	252K	132.72K	+100.00%
Jun 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0%	9.73K	18.48K	9.73K	+100.00%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0%	77.34K	18.25K	-56.16K	-42.07%
Mar 31, 2025	MORGAN STANLEY	0.01%	570.01K	134.75K	19.52K	+3.55%
Mar 31, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.01%	650K	153.66K	0	0
Mar 31, 2025	AXA S.A.	0.01%	691.12K	163.38K	-2.38M	-77.50%
Mar 31, 2025	NORTHERN TRUST CORP	0.02%	1.25M	296.4K	-103.72K	-7.64%
Mar 31, 2025	PALE FIRE CAPITAL SE	0.03%	2.04M	481.16K	633.4K	+45.18%
Mar 31, 2025	ENSIGN PEAK ADVISORS, INC	0.04%	2.24M	528.51K	-310.8K	-12.21%
Mar 31, 2025	INTECH INVESTMENT MANAGEMENT LLC	0%	57.96K	13.7K	57.96K	+100.00%
Mar 31, 2025	INVESCO LTD.	0%	58.19K	13.76K	-3.89K	-6.26%
Mar 31, 2025	SG AMERICAS SECURITIES, LLC	0%	91.49K	22K	-91.67K	-50.05%
Mar 31, 2025	UBS OCONNOR LLC	0%	252.6K	59.61K	-1.01M	-80.02%
Mar 31, 2025	KINGDON CAPITAL MANAGEMENT, L.L.C.	0.11%	7M	1.65M	2.06M	+41.79%
Mar 31, 2025		0.12%	7.31M	1.75M	0	0
Mar 31, 2025	VANGUARD GROUP INC	0.13%	8.07M	1.9M	-133.39K	-1.63%
Mar 31, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	0.27%	16.92M	4M	0	0
Mar 31, 2025	MIRAE ASSET GLOBAL ETFS HOLDINGS LTD.	0%	100.69K	23.8K	4.3K	+4.46%
Mar 31, 2025	BLACKROCK, INC.	0.19%	11.43M	2.7M	369.66K	+3.34%
Mar 31, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0%	51.64K	12K	0	0
Mar 31, 2025	BANK OF NEW YORK MELLON CORP	0.01%	344.75K	81.5K	0	0
Mar 31, 2025	VOYA INVESTMENT MANAGEMENT LLC	0%	59.32K	14.02K	620	+1.06%
Mar 31, 2025	CIBC PRIVATE WEALTH GROUP, LLC	0%	64.99K	13.79K	64.99K	+100.00%
Mar 31, 2025	VIRTU FINANCIAL LLC	0%	67.31K	16K	67.31K	+100.00%
Mar 31, 2025	STIFEL FINANCIAL CORP	0%	75.55K	17.86K	-57	-0.08%
Mar 31, 2025	XTX TOPCO LTD	0%	57.8K	13.67K	57.8K	+100.00%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.01%	481.53K	113.83K	43.32K	+9.89%
Mar 31, 2025	NEA MANAGEMENT COMPANY, LLC	0.24%	14.99M	3.54M	0	0
Mar 31, 2025	ALLIANCEBERNSTEIN L.P.	0%	109.57K	25.9K	0	0
Mar 31, 2025	SIMPLEX TRADING, LLC	0%	111.7K	26K	-80.2K	-41.79%
Mar 31, 2025	BARCLAYS PLC	0%	185.08K	44K	-81.07K	-30.46%
Mar 31, 2025	RHUMBLINE ADVISERS	0%	188.42K	44.45K	9.69K	+5.42%
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	0%	258.76K	61.17K	0	0
Mar 31, 2025	DEUTSCHE BANK AG\	0%	267.63K	64.23K	0	0
Mar 31, 2025	CITIGROUP INC	0%	122.36K	28.93K	-14.85K	-10.82%
Mar 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0%	162.7K	39.05K	-70.8K	-30.32%
Mar 31, 2025	JPMORGAN CHASE & CO	0%	165.44K	39.11K	-294.22K	-64.01%
Mar 31, 2025	GROUP ONE TRADING, L.P.	0%	172.11K	40.69K	-625.3K	-78.42%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0%	273.87K	64.74K	-203.77K	-42.66%
Mar 31, 2025	CITADEL ADVISORS LLC	0%	291.8K	68.98K	126.3K	+76.31%
Mar 31, 2025	SCHONFELD STRATEGIC ADVISORS LLC	0.01%	335.44K	79.3K	-1.06M	-75.92%
Mar 31, 2025	STATE STREET CORP	0.05%	3.06M	722.22K	-2.22K	-0.07%
Mar 31, 2025	AQR CAPITAL MANAGEMENT LLC	0%	86.96K	20.56K	60.12K	+224.02%
Mar 31, 2025	COREBRIDGE FINANCIAL, INC.	0%	83.6K	19.76K	58	+0.07%
Mar 31, 2025	WELLS FARGO & COMPANY/MN	0%	81.54K	19.28K	3.02K	+3.84%
Mar 31, 2025	TD WATERHOUSE CANADA INC.	0%	45K	9.81K	0	0
Mar 31, 2025	NEUBERGER BERMAN GROUP LLC	0%	44.67K	10.56K	44.67K	+100.00%
Mar 31, 2025	ORBIMED ADVISORS LLC	0.11%	6.78M	1.6M	-357K	-5.00%
Mar 31, 2025	JANE STREET GROUP, LLC	0%	45.8K	10.83K	45.8K	+100.00%
Mar 31, 2025	UBS GROUP AG	0.08%	5.04M	1.19M	4.11M	+445.70%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.06%	3.62M	855.79K	122.47K	+3.50%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.6%	1.06M	1.47M	986.14K	+1,354.81%
Mar 31, 2024	UBS OCONNOR LLC	0.75%	1.34M	1.86M	-407.52K	-23.38%
Mar 31, 2024	MORGAN STANLEY	0.79%	1.41M	1.95M	1.01M	+250.40%
Mar 31, 2024	AVIDITY PARTNERS MANAGEMENT LP	1.36%	2.41M	3.35M	2.41M	+100.00%
Mar 31, 2024	ENSIGN PEAK ADVISORS, INC	1.37%	2.44M	3.39M	2.44M	+100.00%
Mar 31, 2024	STATE STREET CORP	1.42%	2.52M	3.51M	95.77K	+3.94%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	1.66%	2.95M	4.09M	142.98K	+5.10%
Mar 31, 2024	AXA S.A.	1.73%	3.07M	4.27M	840	+0.03%
Mar 31, 2024	KINGDON CAPITAL MANAGEMENT, L.L.C.	1.95%	3.47M	4.83M	0	0
Mar 31, 2024	PERCEPTIVE ADVISORS LLC	1.99%	3.55M	4.93M	0	0
Mar 31, 2024	SIO CAPITAL MANAGEMENT, LLC	2.02%	3.59M	4.99M	0	0
Mar 31, 2024	ORBIMED ADVISORS LLC	4.01%	7.13M	9.92M	0	0
Mar 31, 2024	VANGUARD GROUP INC	4.4%	7.83M	10.88M	-181.14K	-2.26%
Mar 31, 2024	BLACKROCK INC.	4.91%	8.74M	12.14M	318.34K	+3.78%
Mar 31, 2024	NEA MANAGEMENT COMPANY, LLC	8.43%	14.99M	20.83M	0	0
Mar 31, 2024	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	9.51%	16.92M	23.51M	0	0
Mar 31, 2024	AMUNDI	0.05%	81.31K	97.57K	0	0
Mar 31, 2024	STIFEL FINANCIAL CORP	0.05%	86.23K	119.86K	-4.23K	-4.67%
Mar 31, 2024	PROPEL BIO MANAGEMENT, LLC	0.3%	535K	743.65K	0	0
Mar 31, 2024	POINT72 ASSET MANAGEMENT, L.P.	0.37%	650K	903.5K	0	0
Mar 31, 2024	ADAGE CAPITAL PARTNERS GP, L.L.C.	2.41%	4.28M	5.94M	0	0
Mar 31, 2024	SOLEUS CAPITAL MANAGEMENT, L.P.	2.58%	4.58M	6.37M	4.58M	+100.00%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.19%	335.97K	467K	-9.98K	-2.88%
Mar 31, 2024	LPL FINANCIAL LLC	0.01%	11.5K	15.99K	0	0
Mar 31, 2024	PATHSTONE HOLDINGS, LLC	0.01%	12.64K	17.57K	0	0
Mar 31, 2024	DIMENSIONAL FUND ADVISORS LP	0.03%	55.3K	76.86K	0	0
Mar 31, 2024	BNP PARIBAS ARBITRAGE, SNC	0.03%	61.58K	85.59K	-221.97K	-78.28%
Mar 31, 2024	TOTAL CLARITY WEALTH MANAGEMENT, INC.	0.01%	13.68K	19.02K	13.68K	+100.00%
Mar 31, 2024	PRINCIPAL FINANCIAL GROUP INC	0.01%	13.69K	19.03K	-2.94K	-17.65%
Mar 31, 2024	NEW YORK STATE COMMON RETIREMENT FUND	0.03%	51.55K	72K	0	0
Mar 31, 2024	HOLISTIC PLANNING, LLC	0.01%	13.8K	19.18K	13.8K	+100.00%
Mar 31, 2024	GRIMES & COMPANY, INC.	0.01%	15K	20.85K	0	0
Mar 31, 2024	VICTORY CAPITAL MANAGEMENT INC	0.01%	15.95K	22.18K	-1.13K	-6.59%
Mar 31, 2024	LEXAURUM ADVISORS, LLC	0.01%	16K	22.24K	0	0
Mar 31, 2024	BLEICHROEDER LP	0.01%	17.87K	24.83K	0	0
Mar 31, 2024	CASSADY SCHILLER WEALTH MANAGEMENT, LLC	0.01%	20K	27.8K	20K	+100.00%
Mar 31, 2024	SG AMERICAS SECURITIES, LLC	0.01%	20.82K	29K	-26.85K	-56.32%
Mar 31, 2024	GROUP ONE TRADING, L.P.	0.01%	21.25K	29.53K	-49.52K	-69.98%
Mar 31, 2024	PRIVATE ADVISOR GROUP, LLC	0.01%	21.8K	30.3K	0	0
Mar 31, 2024	PROSHARE ADVISORS LLC	0.01%	22.51K	31.29K	2.13K	+10.45%
Mar 31, 2024	COMMONWEALTH EQUITY SERVICES, LLC	0.01%	25.1K	35K	25.1K	+100.00%
Mar 31, 2024	RESOURCES INVESTMENT ADVISORS, LLC.	0.02%	28.47K	39.58K	2.67K	+10.36%
Mar 31, 2024	PNC FINANCIAL SERVICES GROUP, INC.	0.02%	30.16K	41.92K	0	0
Mar 31, 2024	PALE FIRE CAPITAL SE	0.02%	38.07K	52.91K	38.07K	+100.00%
Mar 31, 2024	WELLS FARGO & COMPANY/MN	0.02%	40.96K	56.94K	5.94K	+16.96%
Mar 31, 2024	VONTOBEL HOLDING LTD.	0.03%	45K	62.55K	0	0
Mar 31, 2024	CIBC PRIVATE WEALTH GROUP, LLC	0.03%	45K	63.45K	0	0
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	0.03%	45.68K	63.5K	0	0
Mar 31, 2024	JPMORGAN CHASE & CO	0.03%	51.13K	71.07K	-28.68K	-35.94%
Mar 31, 2024	AMERICAN INTERNATIONAL GROUP, INC.	0.03%	61.74K	85.81K	537	+0.88%
Mar 31, 2024	LIGHTHOUSE INVESTMENT PARTNERS, LLC	0.04%	70.42K	97.89K	70.42K	+100.00%
Mar 31, 2024	CITADEL ADVISORS LLC	0.04%	74K	102.86K	19.4K	+35.53%
Mar 31, 2024	JANE STREET GROUP, LLC	0.04%	77.45K	107.66K	-51.82K	-40.09%
Mar 31, 2024	INVESCO LTD.	0.06%	98.62K	137.09K	2.2K	+2.28%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.06%	102.71K	142.77K	-110.18K	-51.75%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.07%	122.5K	170.28K	93.9K	+328.32%
Mar 31, 2024	CITIGROUP INC	0.07%	127.05K	176.6K	109.42K	+620.65%
Mar 31, 2024	UBS GROUP AG	0.07%	129.08K	179.43K	127.86K	+10,437.47%
Mar 31, 2024	RHUMBLINE ADVISERS	0.09%	163.42K	227.14K	3.05K	+1.90%
Mar 31, 2024	KNOTT DAVID M JR	0.1%	180.99K	252K	61.69K	+51.71%
Mar 31, 2024	MILLENNIUM MANAGEMENT LLC	0.15%	258.76K	359.68K	-1.41M	-84.45%
Mar 31, 2024	GSA CAPITAL PARTNERS LLP	0.18%	321.02K	446K	-624.15K	-66.04%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.18%	323.84K	450.14K	0	0
Mar 31, 2024	NEW LEAF VENTURE PARTNERS, L.L.C.	0.19%	335K	465.65K	0	0
Mar 31, 2024	ROYCE & ASSOCIATES LP	0.19%	342.36K	475.89K	-46K	-11.84%
Mar 31, 2024	SIMPLIFY ASSET MANAGEMENT INC.	0.23%	400K	556K	0	0
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.25%	438.11K	608.98K	0	0
Mar 31, 2024	BARCLAYS PLC	0.25%	448.71K	623K	-80.89K	-15.27%
Mar 31, 2024	PARKMAN HEALTHCARE PARTNERS LLC	0.45%	805.36K	1.12M	38.03K	+4.96%
Mar 31, 2024	SCHONFELD STRATEGIC ADVISORS LLC	0.51%	915K	1.27M	365.7K	+66.58%
Mar 31, 2024	NORTHERN TRUST CORP	0.59%	1.05M	1.47M	-8.5K	-0.80%
Dec 31, 2023	VIRTU FINANCIAL LLC	0.06%	127.72K	107K	127.72K	+100.00%
Dec 31, 2023	KNOTT DAVID M JR	0.06%	119.3K	100K	119.3K	+100.00%
Dec 31, 2023	INVESCO LTD.	0.05%	96.43K	80.85K	15.4K	+19.00%
Dec 31, 2023	STIFEL FINANCIAL CORP	0.05%	90.45K	75.85K	10.17K	+12.67%
Dec 31, 2023	AMUNDI	0.04%	81.31K	66.77K	81.31K	+100.00%
Dec 31, 2023	JPMORGAN CHASE & CO	0.04%	79.81K	66.92K	0	0
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.04%	72.79K	61.03K	23.2K	+46.77%
Dec 31, 2023	GROUP ONE TRADING, L.P.	0.04%	70.76K	59.34M	-155.6K	-68.74%
Dec 31, 2023	XTX TOPCO LTD	0.04%	69.09K	57.93K	69.09K	+100.00%
Dec 31, 2023	SQUAREPOINT OPS LLC	0.03%	64.76K	54.3K	64.76K	+100.00%
Dec 31, 2023	AMERICAN INTERNATIONAL GROUP, INC.	0.03%	61.2K	51.32K	-247	-0.40%
Dec 31, 2023	DIMENSIONAL FUND ADVISORS LP	0.03%	55.3K	46.37K	0	0
Dec 31, 2023	CITADEL ADVISORS LLC	0.03%	54.6K	45.78K	-80.8K	-59.68%
Dec 31, 2023	NEW YORK STATE COMMON RETIREMENT FUND	0.03%	51.55K	43K	-417	-0.80%
Dec 31, 2023	JANE STREET GROUP, LLC	0.07%	129.27K	108.4K	115.91K	+867.11%
Dec 31, 2023	UBS OCONNOR LLC	0.88%	1.74M	1.46M	183.05K	+11.73%
Dec 31, 2023	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	8.59%	16.92M	14.18M	955.2K	+5.98%
Dec 31, 2023	NEA MANAGEMENT COMPANY, LLC	7.61%	14.99M	12.57M	0	0
Dec 31, 2023	BLACKROCK INC.	4.27%	8.42M	7.06M	260.68K	+3.20%
Dec 31, 2023	VANGUARD GROUP INC	4.07%	8.01M	6.72M	184.15K	+2.35%
Dec 31, 2023	ORBIMED ADVISORS LLC	3.62%	7.13M	5.98M	0	0
Dec 31, 2023	ADAGE CAPITAL PARTNERS GP, L.L.C.	2.17%	4.28M	3.59M	0	0
Dec 31, 2023	SIO CAPITAL MANAGEMENT, LLC	1.82%	3.59M	3.01M	989.42K	+38.07%
Dec 31, 2023	PERCEPTIVE ADVISORS LLC	1.8%	3.55M	2.97M	0	0
Dec 31, 2023	KINGDON CAPITAL MANAGEMENT, L.L.C.	1.76%	3.47M	2.91M	1.5M	+76.00%
Dec 31, 2023	AXA S.A.	1.56%	3.07M	2.58M	-74.33K	-2.36%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.42%	2.8M	2.35M	159.53K	+6.04%
Dec 31, 2023	STATE STREET CORP	1.23%	2.43M	2.04M	49.16K	+2.07%
Dec 31, 2023	ARMISTICE CAPITAL, LLC	0.98%	1.94M	1.62M	-420K	-17.83%
Dec 31, 2023	RHUMBLINE ADVISERS	0.08%	160.37K	134.54K	0	0
Dec 31, 2023	AQR CAPITAL MANAGEMENT LLC	0.08%	164.34K	137.8K	103.05K	+168.14%
Dec 31, 2023	ACADIAN ASSET MANAGEMENT LLC	0.09%	181.61K	152K	181.61K	+100.00%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.11%	212.89K	178.4K	-160.31K	-42.96%
Dec 31, 2023	BNP PARIBAS ARBITRAGE, SNC	0.14%	283.54K	237.75K	236.9K	+507.88%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.16%	323.84K	271.54K	0	0
Dec 31, 2023	NEW LEAF VENTURE PARTNERS, L.L.C.	0.17%	335K	281.4K	0	0
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.18%	345.95K	290.08K	-128.74K	-27.12%
Dec 31, 2023	ROYCE & ASSOCIATES LP	0.2%	388.36K	325.64K	269.36K	+226.34%
Dec 31, 2023	SIMPLIFY ASSET MANAGEMENT INC.	0.2%	400K	335.4K	0	0
Dec 31, 2023	MORGAN STANLEY	0.2%	401.37K	336.55K	159.63K	+66.03%
Dec 31, 2023	NUVEEN ASSET MANAGEMENT, LLC	0.22%	438.11K	367.36K	0	0
Dec 31, 2023	BARCLAYS PLC	0.27%	529.6K	443K	147.47K	+38.59%
Dec 31, 2023		0.27%	535K	448.6K	535K	+100.00%
Dec 31, 2023	SCHONFELD STRATEGIC ADVISORS LLC	0.28%	549.3K	460.59K	-36.74K	-6.27%
Dec 31, 2023	POINT72 ASSET MANAGEMENT, L.P.	0.33%	650K	545.03K	0	0
Dec 31, 2023	PARKMAN HEALTHCARE PARTNERS LLC	0.39%	767.33K	643.41K	-32.67K	-4.08%
Dec 31, 2023	GSA CAPITAL PARTNERS LLP	0.48%	945.17K	793K	323.58K	+52.06%
Dec 31, 2023	NORTHERN TRUST CORP	0.54%	1.06M	891.31K	-4.71K	-0.44%
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	0.84%	1.66M	1.4M	-1.95M	-53.97%

Insiders

Among the XFOR insiders holding of 1.15% of the stake in company, SVLSF V, LLC, 10 percent owner, holds the largest shares of 1.85M. RAGAN PAULA, President and CEO, is the second largest XFOR insider with ownership of 1.09M shares. NESSI CLAUDIO, director, stands third with possession of 867.64K shares of that stake.

Insiders	Designation	Shares Held
SVLSF V, LLC	10 percent owner	1.85M
RAGAN PAULA	President and CEO	1.09M
NESSI CLAUDIO	director	867.64K
NEOMED INNOVATION V L.P.	10 percent owner	867.64K
DIBIASE MARY	Chief Operating Officer	490.98K
GERNGROSS TILLMAN U.	director	392.82K
TAVERAS ARTHUR	Chief Scientific Officer	388.03K
CRAIG ADAM R	Executive Chairman	376.09K
EMBL TECHNOLOGY FUND II GMBH & CO. KG	10 percent owner	370.45K
STEWART MURRAY	Interim Chief Medical Officer	146.5K
MEISNER DEREK M	Chief Legal Officer	145.16K
WYZGA MICHAEL S	director	76.67K
SKERLJ RENATO	Chief Scientific Officer	42.08K
BALDRY MARK	Chief Commercial Officer	25.34K
ARBET-ENGELS CHRISTOPHE	Chief Medical Officer	14.21K
MCGUIRE TERRANCE		12.35K
CADAVID DIEGO	Chief Medical Officer	7.11K
MOSTAFA ADAM S.	Chief Financial Officer	0

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Oct 23, 2025	CRAIG ADAM R	PURCHASE	2.90	86.21K	250K	376.09K
May 16, 2025	BALDRY MARK	PURCHASE	2.48	1.03K	2.56K	25.34K
Jan 24, 2025	ARBET-ENGELS CHRISTOPHE	SALE	0.45	11.62K	5.28K	14.21K
Jan 24, 2025	RAGAN PAULA	SALE	0.45	76.47K	34.72K	1.09M
Jan 24, 2025	MOSTAFA ADAM S.	SALE	0.45	74.77K	33.95K	0
Jan 24, 2025	BALDRY MARK	SALE	0.45	29.16K	13.24K	94.12K
Jan 24, 2025	DIBIASE MARY	SALE	0.45	22.26K	10.09K	490.98K
Nov 15, 2024	BALDRY MARK	PURCHASE	0.34	13.4K	4.6K	129.17K
Nov 15, 2024	RAGAN PAULA	SALE	0.39	31.9K	12.58K	993.92K
Oct 15, 2024	RAGAN PAULA	SALE	0.56	31.9K	17.93K	1.03M
Oct 07, 2024	TAVERAS ARTHUR	SALE	0.56	76.92K	43.31K	388.03K
Oct 07, 2024	BALDRY MARK	SALE	0.58	11.13K	6.51K	48.51K
Oct 07, 2024	RAGAN PAULA	SALE	0.55	239.44K	131.52K	1.06M
Oct 07, 2024	DIBIASE MARY	SALE	0.57	67.7K	38.33K	452.06K
Oct 07, 2024	MOSTAFA ADAM S.	SALE	0.55	230.65K	126.9K	0
Sep 09, 2024	DIBIASE MARY	SALE	0.66	2.64K	1.74K	289.11K
May 17, 2024	BALDRY MARK	PURCHASE	0.68	21.65K	14.65K	115.77K
Mar 11, 2024	DIBIASE MARY	SALE	0.88	15.41K	13.59K	291.75K
Mar 11, 2024	MOSTAFA ADAM S.	SALE	0.88	52.5K	46.35K	0
Mar 11, 2024	RAGAN PAULA	SALE	0.88	49.68K	43.86K	765.07K
Mar 11, 2024	TAVERAS ARTHUR	SALE	0.88	14.24K	12.55K	234.3K
Feb 12, 2024	DIBIASE MARY	SALE	1.01	3.68K	3.71K	307.16K
Feb 12, 2024	TAVERAS ARTHUR	SALE	1.01	787	792.67	248.54K
Feb 12, 2024	RAGAN PAULA	SALE	1.01	21.7K	21.89K	814.75K
Feb 12, 2024	MOSTAFA ADAM S.	SALE	1.01	27.72K	27.97K	52.5K
Nov 03, 2023	RAGAN PAULA	SALE	0.90	39.91K	35.92K	836.44K
Nov 01, 2023	BALDRY MARK	SALE	0.73	10.26K	7.49K	24.69K
Nov 01, 2023	DIBIASE MARY	SALE	0.73	67.7K	49.42K	310.84K
Nov 01, 2023	TAVERAS ARTHUR	SALE	0.73	67.7K	49.42K	249.32K
Nov 01, 2023	MOSTAFA ADAM S.	SALE	0.73	230.65K	168.37K	80.22K
Nov 01, 2023	RAGAN PAULA	SALE	0.73	199.53K	145.66K	876.35K
Sep 08, 2023	DIBIASE MARY	SALE	1.25	2.64K	3.3K	147.89K
Aug 18, 2023	WYZGA MICHAEL S	PURCHASE	1.20	25K	29.88K	76.67K
Aug 10, 2023	STEWART MURRAY	SALE	1.06	130.06K	137.86K	146.5K
Jun 30, 2023	DIBIASE MARY	SALE	1.89	464	876.96	150.54K
Jun 30, 2023	MOSTAFA ADAM S.	SALE	1.89	2.64K	4.99K	80.22K
Jun 23, 2023	DIBIASE MARY	SALE	1.93	857	1.65K	151K
Jun 23, 2023	RAGAN PAULA	SALE	1.92	6.72K	12.91K	543.8K
Jun 23, 2023	MOSTAFA ADAM S.	SALE	1.93	5.42K	10.45K	82.86K
Jun 15, 2023	DIBIASE MARY	SALE	2.23	857	1.91K	151.86K
Jun 15, 2023	MOSTAFA ADAM S.	SALE	2.22	5.42K	12.03K	88.28K
Jun 15, 2023	RAGAN PAULA	SALE	2.23	6.72K	14.99K	550.52K
May 31, 2023	RAGAN PAULA	SALE	1.95	6.29K	12.27K	557.25K
Mar 10, 2023	TAVERAS ARTHUR	SALE	0.84	16.81K	14.12K	86.37K
Mar 10, 2023	DIBIASE MARY	SALE	0.84	18.19K	15.28K	152.71K
Mar 10, 2023	MOSTAFA ADAM S.	SALE	0.84	52.5K	44.1K	93.7K
Mar 10, 2023	RAGAN PAULA	SALE	0.84	49.68K	41.73K	563.54K
Feb 13, 2023	MOSTAFA ADAM S.	SALE	0.93	27.72K	25.78K	146.2K
Feb 13, 2023	TAVERAS ARTHUR	SALE	0.93	928	863.04	103.18K
Feb 13, 2023	RAGAN PAULA	SALE	0.93	21.7K	20.18K	613.22K
Feb 13, 2023	DIBIASE MARY	SALE	0.93	4.35K	4.04K	170.91K
Aug 17, 2022	MOSTAFA ADAM S.	SALE	0.00	10.83K	-	173.92K
Aug 17, 2022	MEISNER DEREK M	SALE	1.16	8.33K	9.63K	145.16K
Aug 17, 2022	DIBIASE MARY	SALE	0.00	1.71K	-	177.9K
Aug 17, 2022	RAGAN PAULA	SALE	0.00	13.45K	-	634.91K
Jun 30, 2022	MOSTAFA ADAM S.	SALE	0.00	2.64K	-	184.75K
Jun 30, 2022	DIBIASE MARY	SALE	0.00	1.58K	-	179.61K
Jun 24, 2022	MOSTAFA ADAM S.	SALE	0.00	5.42K	-	187.39K
Jun 24, 2022	MEISNER DEREK M	SALE	1.06	4.17K	4.42K	153.49K
Jun 24, 2022	RAGAN PAULA	SALE	0.00	6.72K	-	648.36K
Jun 24, 2022	DIBIASE MARY	SALE	0.00	856	-	181.19K
Jun 16, 2022	MOSTAFA ADAM S.	SALE	0.00	5.42K	-	192.81K
Jun 16, 2022	MEISNER DEREK M	SALE	1.01	4.17K	4.21K	157.66K
Jun 16, 2022	DIBIASE MARY	SALE	0.00	856	-	182.04K
Jun 16, 2022	RAGAN PAULA	SALE	0.00	6.72K	-	655.08K
Jun 03, 2022	RAGAN PAULA	SALE	1.21	6.29K	7.61K	661.81K
Feb 11, 2022	RAGAN PAULA	SALE	1.52	21.7K	32.98K	447.31K
Feb 11, 2022	CADAVID DIEGO	SALE	1.53	928	1.42K	7.11K
Feb 11, 2022	MEISNER DEREK M	SALE	1.53	15.91K	24.34K	56.82K
Feb 11, 2022	MOSTAFA ADAM S.	SALE	1.52	27.72K	42.14K	93.22K
Feb 11, 2022	DIBIASE MARY	SALE	1.52	12.55K	19.07K	77.9K
Aug 17, 2021	RAGAN PAULA	SALE	5.10	13.45K	68.58K	469K
Aug 17, 2021	MOSTAFA ADAM S.	SALE	5.10	10.83K	55.24K	120.95K
Aug 17, 2021	MEISNER DEREK M	SALE	5.10	8.33K	42.49K	72.73K
Jul 15, 2021	RAGAN PAULA	SALE	5.78	13.45K	77.73K	482.45K
Jun 30, 2021	MOSTAFA ADAM S.	SALE	6.64	2.64K	17.54K	131.78K
Jun 24, 2021	MEISNER DEREK M	SALE	7.00	4.17K	29.16K	81.06K
Jun 24, 2021	MOSTAFA ADAM S.	SALE	7.01	5.42K	37.97K	134.42K
Jun 15, 2021	MEISNER DEREK M	SALE	7.84	4.17K	32.66K	72.73K
Jun 15, 2021	MOSTAFA ADAM S.	SALE	7.84	5.42K	42.47K	123.59K
Jun 02, 2021	RAGAN PAULA	SALE	9.50	2.4K	22.8K	406.25K
Jun 01, 2021	RAGAN PAULA	SALE	9.41	4.1K	38.62K	408.65K
May 03, 2021	RAGAN PAULA	SALE	8.33	2.4K	19.99K	412.75K
Apr 05, 2021	RAGAN PAULA	SALE	9.17	2.4K	22.01K	415.15K
Mar 02, 2021	RAGAN PAULA	SALE	9.74	2.4K	23.38K	272.92K
Feb 02, 2021	RAGAN PAULA	SALE	7.88	2.4K	18.91K	275.32K
Jan 05, 2021	RAGAN PAULA	SALE	7.00	2.4K	16.8K	277.72K
Dec 23, 2020	RAGAN PAULA	SALE	7.00	4.8K	33.6K	280.12K
Oct 05, 2020	RAGAN PAULA	SALE	7.00	1.8K	12.58K	284.92K
Oct 02, 2020	RAGAN PAULA	SALE	7.00	603	4.22K	286.72K
Sep 21, 2020	MOSTAFA ADAM S.	SALE	7.08	10.83K	76.7K	29.59K
Sep 09, 2020	RAGAN PAULA	SALE	8.04	8.84K	71.07K	287.32K
Sep 09, 2020	SKERLJ RENATO	SALE	8.05	5.83K	46.96K	42.08K
Sep 09, 2020	MEISNER DEREK M	SALE	8.05	8.33K	67.09K	16.67K
Sep 02, 2020	RAGAN PAULA	SALE	7.99	2.4K	19.18K	296.16K
Aug 03, 2020	RAGAN PAULA	SALE	7.45	2.4K	17.88K	208.91K
Jul 02, 2020	RAGAN PAULA	SALE	9.05	2.4K	21.72K	211.31K
Jun 30, 2020	MOSTAFA ADAM S.	SALE	9.04	1.73K	15.59K	8.84K
Jun 03, 2020	RAGAN PAULA	SALE	8.88	9.71K	86.2K	213.71K
Jun 02, 2020	RAGAN PAULA	SALE	8.65	2.4K	20.76K	223.42K
Jun 01, 2020	RAGAN PAULA	SALE	8.63	4.28K	36.89K	225.82K
May 04, 2020	RAGAN PAULA	SALE	8.92	2.4K	21.41K	230.09K
Apr 02, 2020	RAGAN PAULA	SALE	8.40	2.4K	20.16K	232.49K
Mar 02, 2020	RAGAN PAULA	SALE	10.64	2.4K	25.54K	234.89K
Nov 20, 2017	NEOMED INNOVATION V L.P.	PURCHASE	10.00	300K	3M	867.64K
Nov 20, 2017	SVLSF V, LLC	PURCHASE	10.00	483.45K	4.83M	1.85M
Nov 20, 2017	NESSI CLAUDIO	PURCHASE	10.00	300K	3M	867.64K
Nov 20, 2017	EMBL TECHNOLOGY FUND II GMBH & CO. KG	PURCHASE	10.00	20K	200K	370.45K
Nov 20, 2017	GERNGROSS TILLMAN U.	PURCHASE	10.00	200K	2M	392.82K
Nov 20, 2017	MCGUIRE TERRANCE	PURCHASE	10.00	3.31K	33.05K	12.35K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE86.21K1

SALES00

NET SHARES86.21K1

SHARES HELD376.09K1

% NET SHARES-77.08%0%

Frequently Asked Questions