How many institutions own SVRA stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own SVRA shares is 201, representing 97.78% of the company's common stock.

Who are the major shareholders selling Savara Inc. stock?

DEUTSCHE BANK AG\, in the last quarter, reduced its stake in SVRA by -3.09% restricting it's holding to 824.72 thousand shares of worth nearly $4.97M. VIRTUS INVESTMENT ADVISERS, INC. also lessened -23.65% of the SVRA shares from its portfolio, reducing its holding to 38.44 thousand shares of worth $231.81K. ENTRYPOINT CAPITAL, LLC also shunned SVRA shares holding by -50.13% last quarter which brought its holding to 40.72 thousand shares worth $245.52K.

Investors who are buying SVRA stock?

As per its latest 13F filing, increased its stake in SVRA by 100% in the last quarter. The institutional holder raised its holding to 605.28 thousand shares having worth more than $3.65M. CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD. also added 9.44% more shares of SVRA to its portfolio, raising its holding to 33.16 thousand shares of worth $199.93K. PROSHARE ADVISORS LLC also increased its SVRA shares holding by 35.49% which brought its holding to 34.87 thousand shares worth $210.26K.

SVRA's major insiders: who are they?

The insider with the most stakes in SVRA is Yang Rick , 10 percent owner at the company. Additionally, SVRA stock is highly held by 10 percent owner Walker Paul Edward and 10 percent owner Behbahani Ali among others.

Did an insider recently sell SVRA stock?

Company executives, directors, and other insiders own 2.33% percent of Savara Inc.'s stock. Within the last six months, there have been 1 transaction(s) in which SVRA insiders have sold stock, totaling 20K shares. Insiders that have sold shares include RAMSAY DAVID A, HAWKINS RICHARD J, and PAULS MATTHEW.

Which insider recently purchased SVRA stock?

There have been 0 transaction(s) during the past 6-months in which Savara Inc. insiders have bought stock, totalling 0 shares

How much of SVRA does insiders own?

Around 2.53M Savara Inc. shares are held by insiders, which represents about 2.33% of SVRA stock.

Who is the insider with the largest stake?

SVRA 10 percent owner, Yang Rick holds the largest portfolio of the company's shares. SVRA shares owned by Yang total nearly 24.47 million.

Which institution holds the most shares in SVRA?

is the largest institutional owner in SVRA which holds 605.28 thousand shares worth $3.65M or 0.28% of the total SVRA shares outstanding followed by CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD. with ownership of 33.16 thousand shares representing 0.02% of the SVRA ownership. POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY is the third largest stakeholder with 33.93 thousand shares or 0.02% of the ownership worth more than $204.57K.

Is Savara Inc. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the SVRA is concerned, it is a stock which is optionable.

Is there a short position on SVRA's shares?

Number of SVRA shares short is 17.63M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding SVRA shares are there?

As of today, 172.84M shares of SVRA are outstanding.

Is there many float in SVRA stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, SVRA has 86.68M shares in float.

SVRA short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for SVRA is 16.62.

Savara (SVRA) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares10.2

Short Percent Of Float12.24

Shares Outstanding172.84M

Shares Float86.68M

Shares Short17.63M

Short Ratio16.62

12.24%

Short % of Float

10.2%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

2.33% Percentage of Shares held by All Insiders

97.78% Percentage of Shares held by All Institutions

100.12% Percentage of Float held by Institutions

201

Number of Institutions Holding Shares

Institutional Ownership

About 97.78% of SVRA shares are held by financial institutions. is the top corporate investor, holding 605.28K shares valued at $3.65M. A 0.28% stake in Savara Inc. is owned by the company. CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD. owns 33.16K shares valued at $199.93K, which translates its holding of 0.02% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Dec 31, 2025		0.28%	605.28K	3.65M	605.28K	+100.00%
Dec 31, 2025	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.02%	33.16K	199.93K	2.86K	+9.44%
Dec 31, 2025	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0.02%	33.93K	204.57K	0	0
Dec 31, 2025	PROSHARE ADVISORS LLC	0.02%	34.87K	210.26K	9.13K	+35.49%
Dec 31, 2025	PROFUND ADVISORS LLC	0.02%	35.15K	211.92K	35.15K	+100.00%
Dec 31, 2025	DEUTSCHE BANK AG\	0.38%	824.72K	4.97M	-26.26K	-3.09%
Dec 31, 2025	SIREN, L.L.C.	0.46%	1M	6.03M	1M	+100.00%
Dec 31, 2025	MORGAN STANLEY	1.08%	2.34M	14.1M	420.07K	+21.90%
Dec 31, 2025	VIRTUS INVESTMENT ADVISERS, INC.	0.02%	38.44K	231.81K	-11.91K	-23.65%
Dec 31, 2025	ENTRYPOINT CAPITAL, LLC	0.02%	40.72K	245.52K	-40.93K	-50.13%
Dec 31, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.02%	40.96K	246.98K	-5.35K	-11.54%
Dec 31, 2025	CITADEL ADVISORS LLC	0.36%	774.49K	4.67M	106.39K	+15.92%
Dec 31, 2025	SWEDBANK AB	0.39%	850K	5.13M	300K	+54.55%
Dec 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.54%	1.16M	7M	197.87K	+20.53%
Dec 31, 2025	NAN FUNG TRINITY (HK) LTD	0.78%	1.69M	10.18M	1.69M	+100.00%
Dec 31, 2025	EMERALD MUTUAL FUND ADVISERS TRUST	1.11%	2.4M	14.45M	245.1K	+11.39%
Dec 31, 2025	AFFINITY ASSET ADVISORS, LLC	1.29%	2.8M	16.87M	1.3M	+86.48%
Dec 31, 2025	ROSALIND ADVISORS, INC.	1.57%	3.4M	20.52M	-596.28K	-14.91%
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.58%	3.42M	20.61M	622.11K	+22.25%
Dec 31, 2025	EMERALD ADVISERS, LLC	1.61%	3.5M	21.08M	-33.83K	-0.96%
Dec 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0.15%	332.1K	2M	72K	+27.68%
Dec 31, 2025	SUMMITTX CAPITAL, L.P.	0.17%	373.03K	2.25M	373.03K	+100.00%
Dec 31, 2025	BANK OF AMERICA CORP /DE/	0.2%	423.6K	2.55M	303.61K	+253.03%
Dec 31, 2025	GOLDMAN SACHS GROUP INC	0.24%	516.6K	3.12M	-145.65K	-21.99%
Dec 31, 2025	D. E. SHAW & CO., INC.	0.77%	1.67M	10.07M	1.3M	+348.73%
Dec 31, 2025	PERCEPTIVE ADVISORS LLC	1.11%	2.4M	14.47M	2.4M	+100.00%
Dec 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	1.24%	2.67M	16.13M	30.93K	+1.17%
Dec 31, 2025	WOODLINE PARTNERS LP	1.96%	4.24M	25.6M	4.01M	+1,689.32%
Dec 31, 2025	RTW INVESTMENTS, LP	2.75%	5.95M	35.89M	5.95M	+100.00%
Dec 31, 2025	POLAR CAPITAL HOLDINGS PLC	3.84%	8.31M	50.09M	8.31M	+100.00%
Dec 31, 2025	TCG CROSSOVER MANAGEMENT, LLC	5.71%	12.36M	74.54M	0	0
Dec 31, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	6.27%	13.57M	81.82M	5.61M	+70.38%
Dec 31, 2025	MILLENNIUM MANAGEMENT LLC	0.25%	534.97K	3.23M	-309.21K	-36.63%
Dec 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.25%	543.76K	3.28M	522.39K	+2,445.20%
Dec 31, 2025	JANE STREET GROUP, LLC	0.27%	584.29K	3.52M	-21.28K	-3.51%
Dec 31, 2025	STATE STREET CORP	2%	4.33M	26.13M	1.97M	+83.61%
Dec 31, 2025	SIO CAPITAL MANAGEMENT, LLC	0.28%	613.89K	3.7M	-112.96K	-15.54%
Dec 31, 2025	F/M INVESTMENTS LLC	0.31%	678.81K	4.09M	245.1K	+56.51%
Dec 31, 2025	INVESCO LTD.	0.32%	688.6K	4.15M	517.33K	+302.06%
Dec 31, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.35%	751.26K	4.53M	-105.35K	-12.30%
Dec 31, 2025	SUPERSTRING CAPITAL MANAGEMENT LP	0.46%	995.35K	6M	-313.88K	-23.97%
Dec 31, 2025	NORTHERN TRUST CORP	0.5%	1.08M	6.5M	130.89K	+13.83%
Dec 31, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.54%	1.18M	7.1M	-172.17K	-12.75%
Dec 31, 2025	VR ADVISER, LLC	6.35%	13.74M	82.85M	1.06M	+8.35%
Dec 31, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	8.13%	17.6M	106.13M	0	0
Dec 31, 2025	NEA MANAGEMENT COMPANY, LLC	11.31%	24.47M	147.56M	0	0
Dec 31, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.02%	43.55K	262.59K	5.08K	+13.21%
Dec 31, 2025	SG AMERICAS SECURITIES, LLC	0.02%	45.53K	275K	45.53K	+100.00%
Dec 31, 2025	DYMON ASIA CAPITAL (SINGAPORE) PTE. LTD.	0.02%	46K	277.38K	46K	+100.00%
Dec 31, 2025	SIVIA CAPITAL PARTNERS, LLC	0.02%	48.51K	292.5K	7	+0.01%
Dec 31, 2025	BANK OF NOVA SCOTIA	0.02%	51.7K	311.75K	51.7K	+100.00%
Dec 31, 2025	JUMP FINANCIAL, LLC	0.03%	70.7K	426.29K	70.7K	+100.00%
Dec 31, 2025	JPMORGAN CHASE & CO	0.03%	73.06K	440.55K	9.22K	+14.45%
Dec 31, 2025	OXFORD ASSET MANAGEMENT LLP	0.03%	74.12K	446.91K	74.12K	+100.00%
Dec 31, 2025	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.03%	74.88K	451.54K	-18.99K	-20.23%
Dec 31, 2025	LONGAEVA PARTNERS L.P.	0.58%	1.25M	7.51M	1.25M	+100.00%
Dec 31, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	0.65%	1.41M	8.47M	-582.84K	-29.31%
Dec 31, 2025	VESTAL POINT CAPITAL, LP	0.74%	1.61M	9.68M	-2.41M	-60.00%
Dec 31, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.04%	78.55K	473.66K	18.25K	+30.25%
Dec 31, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.04%	89.86K	541.84K	89.86K	+100.00%
Dec 31, 2025	UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH	0.04%	90K	549.9K	-20K	-18.18%
Dec 31, 2025	GSA CAPITAL PARTNERS LLP	0.07%	140.75K	849K	-231.7K	-62.21%
Dec 31, 2025	WALLEYE CAPITAL LLC	0.07%	150.08K	905.01K	59.06K	+64.89%
Dec 31, 2025	RHUMBLINE ADVISERS	0.07%	152.78K	921.23M	-4.79K	-3.04%
Dec 31, 2025	WELLS FARGO & COMPANY/MN	0.08%	167.64K	1.01M	83.55K	+99.36%
Dec 31, 2025	DIMENSIONAL FUND ADVISORS LP	0.08%	170.13K	1.03M	-530.52K	-75.72%
Dec 31, 2025	UBS GROUP AG	0.09%	202.88K	1.22M	-492.85K	-70.84%
Dec 31, 2025	NUVEEN, LLC	0.13%	272.6K	1.64M	35.77K	+15.10%
Dec 31, 2025	SOFINNOVA INVESTMENTS, INC.	0.14%	304.77K	1.84M	-2.12M	-87.45%
Dec 31, 2025	BARCLAYS PLC	0.14%	306.94K	1.85M	130.42K	+73.89%
Dec 31, 2025	MARSHALL WACE, LLP	2.11%	4.56M	27.5M	4.56M	+100.00%
Dec 31, 2025	STRS OHIO	0.01%	26.5K	159.8K	26.5K	+100.00%
Dec 31, 2025	FARTHER FINANCE ADVISORS, LLC	0.01%	26.9K	162.18K	-2.28K	-7.81%
Dec 31, 2025	NANTAHALA CAPITAL MANAGEMENT, LLC	3.39%	7.34M	44.29M	-1.43M	-16.30%
Dec 31, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	4.56%	9.86M	59.47M	-1.6M	-13.96%
Dec 31, 2025	VANGUARD GROUP INC	4.64%	10.04M	60.55M	1.73M	+20.79%
Dec 31, 2025	BLACKROCK, INC.	5.13%	11.1M	66.92M	2.65M	+31.36%
Dec 31, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.02%	36.56K	220.43K	22.7K	+163.84%
Dec 31, 2025	SKOPOS LABS, INC.	0.02%	36.81K	233K	-61.83K	-62.68%
Dec 31, 2025	BANK OF NEW YORK MELLON CORP	0.14%	312.87K	1.89M	39.51K	+14.46%
Dec 31, 2025	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	0.49%	1.06M	6.4M	1.06M	+100.00%
Dec 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.01%	31.2K	188.16K	6.05K	+24.05%
Sep 30, 2025	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.04%	93.87K	335.11K	-215.97K	-69.70%
Sep 30, 2025	SKOPOS LABS, INC.	0.05%	98.64K	218K	20.73K	+26.61%
Sep 30, 2025	ALLIANCEBERNSTEIN L.P.	0.05%	118.79K	424.08K	-18.3K	-13.35%
Sep 30, 2025	MORGAN STANLEY	0.89%	1.92M	6.85M	1.54M	+401.24%
Sep 30, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	0.92%	1.99M	7.1M	-1.61M	-44.78%
Sep 30, 2025	STATE STREET CORP	1.09%	2.36M	8.42M	-97.08K	-3.95%
Sep 30, 2025	SOFINNOVA INVESTMENTS, INC.	1.12%	2.43M	8.67M	-29.63K	-1.21%
Sep 30, 2025	FARALLON CAPITAL MANAGEMENT LLC	1.16%	2.5M	8.93M	-4.34M	-63.42%
Sep 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	1.22%	2.64M	9.44M	-706.27K	-21.08%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.29%	2.8M	9.98M	-174.52K	-5.88%
Sep 30, 2025	EMERALD ADVISERS, LLC	1.63%	3.53M	12.6M	-5.04K	-0.14%
Sep 30, 2025	EMERALD MUTUAL FUND ADVISERS TRUST	0.99%	2.15M	7.68M	-35.05K	-1.60%
Sep 30, 2025	ROSALIND ADVISORS, INC.	1.85%	4M	14.28M	1.35M	+50.66%
Sep 30, 2025	VESTAL POINT CAPITAL, LP	1.86%	4.02M	14.33M	-7M	-63.55%
Sep 30, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	3.68%	7.96M	28.43M	0	0
Sep 30, 2025	VANGUARD GROUP INC	3.84%	8.31M	29.68M	-140.79K	-1.67%
Sep 30, 2025	BLACKROCK, INC.	3.9%	8.45M	30.16M	-1.33M	-13.58%
Sep 30, 2025	NANTAHALA CAPITAL MANAGEMENT, LLC	4.05%	8.78M	31.33M	450K	+5.41%
Sep 30, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	5.3%	11.46M	40.92M	0	0
Sep 30, 2025	TCG CROSSOVER MANAGEMENT, LLC	5.71%	12.36M	44.13M	0	0
Sep 30, 2025	VR ADVISER, LLC	5.86%	12.68M	45.27M	3.8M	+42.74%
Sep 30, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	8.13%	17.6M	62.83M	0	0
Sep 30, 2025	NEA MANAGEMENT COMPANY, LLC	11.31%	24.47M	87.36M	0	0
Sep 30, 2025	FMR LLC	0%	7.2K	25.71K	1.55K	+27.45%
Sep 30, 2025	SIMPLEX TRADING, LLC	0%	10.3K	36K	-1.53K	-12.94%
Sep 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0%	10.48K	37.41K	9.46K	+930.48%
Sep 30, 2025	AMERITAS INVESTMENT PARTNERS, INC.	0.01%	11.69K	41.73K	0	0
Sep 30, 2025	LEGAL & GENERAL GROUP PLC	0.01%	12.1K	43.2K	-42.6K	-77.87%
Sep 30, 2025		0.01%	12.21K	43.58K	12.21K	+100.00%
Sep 30, 2025	CITIGROUP INC	0.01%	12.94K	46.21K	-40.23K	-75.66%
Sep 30, 2025	PRUDENTIAL FINANCIAL INC	0.01%	13.15K	46.93K	150	+1.15%
Sep 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.01%	13.86K	49.46K	0	0
Sep 30, 2025	CHOREO, LLC	0.01%	14.66K	52.33K	0	0
Sep 30, 2025	OPPENHEIMER & CO INC	0.01%	15.5K	55.34K	0	0
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.01%	25.15K	89.8K	11.68K	+86.70%
Sep 30, 2025	KOVITZ INVESTMENT GROUP PARTNERS, LLC	0.01%	25.21K	90.01K	0	0
Sep 30, 2025	PROSHARE ADVISORS LLC	0.01%	25.74K	91.88K	-6.66K	-20.56%
Sep 30, 2025	Y-INTERCEPT (HONG KONG) LTD	0.01%	26.8K	95.67K	26.8K	+100.00%
Sep 30, 2025	FARTHER FINANCE ADVISORS, LLC	0.01%	29.18K	104.16K	-8.83K	-23.22%
Sep 30, 2025	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.01%	30.3K	108.16K	-4.42K	-12.73%
Sep 30, 2025	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0.02%	33.93K	121.11K	7.7K	+29.37%
Sep 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.02%	46.3K	165.3K	-22.86K	-33.06%
Sep 30, 2025	SIVIA CAPITAL PARTNERS, LLC	0.02%	48.5K	173.15K	7K	+16.87%
Sep 30, 2025	QUADRATURE CAPITAL LTD	0.02%	52.04K	185.26K	33.58K	+181.92%
Sep 30, 2025	STONEPINE CAPITAL MANAGEMENT, LLC	0.03%	60K	214.2K	-25K	-29.41%
Sep 30, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.03%	60.31K	215.29K	-15.33K	-20.27%
Sep 30, 2025	JPMORGAN CHASE & CO	0.03%	63.84K	227.89K	-4.67K	-6.82%
Sep 30, 2025	ENTRYPOINT CAPITAL, LLC	0.04%	81.65K	291.48K	-96.85K	-54.26%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0.04%	84.09K	300.2K	6.2K	+7.96%
Sep 30, 2025	UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH	0.05%	110K	392.7K	0	0
Sep 30, 2025	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.06%	123.79K	441.93K	123.79K	+100.00%
Sep 30, 2025	RHUMBLINE ADVISERS	0.07%	157.57K	562.51K	-12.61K	-7.41%
Sep 30, 2025	TWO SIGMA INVESTMENTS, LP	0.07%	158.02K	564.12K	-124.75K	-44.12%
Sep 30, 2025	INVESCO LTD.	0.08%	171.27K	611.42K	50.38K	+41.67%
Sep 30, 2025	BARCLAYS PLC	0.08%	176.52K	630.16K	-77.31K	-30.46%
Sep 30, 2025	NUVEEN, LLC	0.11%	236.84K	845.5K	-83.44K	-26.05%
Sep 30, 2025	WOODLINE PARTNERS LP	0.11%	237.22K	846.88K	81.36K	+52.20%
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.12%	260.1K	928.56K	260.1K	+100.00%
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.13%	273.36K	975.88K	3.87K	+1.44%
Sep 30, 2025	D. E. SHAW & CO., INC.	0.17%	372.03K	1.33M	292.31K	+366.71%
Sep 30, 2025	GSA CAPITAL PARTNERS LLP	0.17%	372.45K	1.33M	-336.01K	-47.43%
Sep 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.19%	419.8K	1.5M	-106.36K	-20.21%
Sep 30, 2025	F/M INVESTMENTS LLC	0.2%	433.71K	1.55M	118.87K	+37.75%
Sep 30, 2025	SWEDBANK AB	0.25%	550K	1.96M	550K	+100.00%
Sep 30, 2025	JANE STREET GROUP, LLC	0.28%	605.57K	2.16M	605.57K	+100.00%
Sep 30, 2025	ROYAL BANK OF CANADA	0.3%	654.4K	2.34M	612.77K	+1,472.16%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	0.31%	662.25K	2.36M	132.17K	+24.93%
Sep 30, 2025	CITADEL ADVISORS LLC	0.31%	668.11K	2.39M	557.32K	+503.07%
Sep 30, 2025	UBS GROUP AG	0.32%	695.73K	2.48M	479.12K	+221.19%
Sep 30, 2025	DIMENSIONAL FUND ADVISORS LP	0.32%	700.65K	2.5M	55.17K	+8.55%
Sep 30, 2025	SIO CAPITAL MANAGEMENT, LLC	0.34%	726.85K	2.59M	0	0
Sep 30, 2025	MILLENNIUM MANAGEMENT LLC	0.39%	844.18K	3.01M	844.18K	+100.00%
Sep 30, 2025	DEUTSCHE BANK AG\	0.39%	850.98K	3.04M	19.93K	+2.40%
Sep 30, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.4%	856.6K	3.06M	59.48K	+7.46%
Sep 30, 2025	NORTHERN TRUST CORP	0.44%	946.73K	3.38M	-122.92K	-11.49%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.45%	963.8K	3.44M	-31.71K	-3.19%
Sep 30, 2025	AXA INVESTMENT MANAGERS S.A.	0.49%	1.05M	3.76M	1.05M	+100.00%
Sep 30, 2025	SUPERSTRING CAPITAL MANAGEMENT LP	0.6%	1.31M	4.67M	193.86K	+17.38%
Sep 30, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.62%	1.35M	4.82M	40.1K	+3.06%
Sep 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.69%	1.5M	5.36M	1M	+200.00%
Jun 30, 2025	NUVEEN, LLC	0.15%	320.27K	730.22K	-64.83K	-16.83%
Jun 30, 2025	SOFINNOVA INVESTMENTS, INC.	1.14%	2.46M	5.6M	-3.02M	-55.17%
Jun 30, 2025	EMERALD MUTUAL FUND ADVISERS TRUST	1.01%	2.19M	4.99M	171.95K	+8.54%
Jun 30, 2025		0.05%	110K	250.8K	-27.69K	-20.11%
Jun 30, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.37%	797.12K	1.82M	716.09K	+883.74%
Jun 30, 2025	SIO CAPITAL MANAGEMENT, LLC	0.34%	726.85K	1.66M	7.2K	+1.00%
Jun 30, 2025	GSA CAPITAL PARTNERS LLP	0.33%	708.46K	1.62M	620.76K	+707.78%
Jun 30, 2025	DIMENSIONAL FUND ADVISORS LP	0.3%	645.47K	1.47M	356.8K	+123.60%
Jun 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.24%	526.16K	1.2M	-271.17K	-34.01%
Jun 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.23%	500K	1.14M	500K	+100.00%
Jun 30, 2025	F/M INVESTMENTS LLC	0.15%	314.85K	717.85K	91.83K	+41.18%
Jun 30, 2025	RHUMBLINE ADVISERS	0.08%	170.18K	387.99K	16.63K	+10.83%
Jun 30, 2025	INVESCO LTD.	0.06%	120.89K	275.63K	31.63K	+35.44%
Jun 30, 2025	NEA MANAGEMENT COMPANY, LLC	11.31%	24.47M	55.79M	0	0
Jun 30, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	8.13%	17.6M	40.13M	0	0
Jun 30, 2025	TCG CROSSOVER MANAGEMENT, LLC	5.71%	12.36M	28.19M	0	0
Jun 30, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	5.3%	11.46M	26.13M	0	0
Jun 30, 2025	NANTAHALA CAPITAL MANAGEMENT, LLC	3.85%	8.33M	18.98M	250K	+3.10%
Jun 30, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	3.68%	7.96M	18.16M	0	0
Jun 30, 2025	FARALLON CAPITAL MANAGEMENT LLC	3.16%	6.84M	15.58M	0	0
Jun 30, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	1.66%	3.6M	8.21M	2.24M	+164.70%
Jun 30, 2025	QUARRY LP	0.01%	17K	38.76K	10K	+142.86%
Jun 30, 2025	CIBC WORLD MARKETS CORP	0.01%	15.59K	35.54K	-11.14K	-41.67%
Jun 30, 2025	CHOREO, LLC	0.01%	14.66K	33.42K	0	0
Jun 30, 2025	VR ADVISER, LLC	4.1%	8.88M	20.26M	5.63M	+172.72%
Jun 30, 2025	ROSALIND ADVISORS, INC.	1.23%	2.65M	6.05M	0	0
Jun 30, 2025	XTX TOPCO LTD	0.04%	88.1K	200.86K	88.1K	+100.00%
Jun 30, 2025	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0.04%	86.47K	197.14M	0	0
Jun 30, 2025	STONEPINE CAPITAL MANAGEMENT, LLC	0.04%	85K	193.8K	55.92K	+192.31%
Jun 30, 2025	ALGERT GLOBAL LLC	0.04%	79.95K	182K	-53.02K	-39.87%
Jun 30, 2025	D. E. SHAW & CO., INC.	0.04%	79.71K	181.75M	23.45K	+41.69%
Jun 30, 2025	SKOPOS LABS, INC.	0.04%	77.91K	177.64K	54.3K	+229.98%
Jun 30, 2025	MIRAE ASSET GLOBAL ETFS HOLDINGS LTD.	0.03%	69.85K	159.25K	-1.38K	-1.94%
Jun 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.03%	69.17K	157.7K	-8.52K	-10.97%
Jun 30, 2025	ROYAL BANK OF CANADA	0.02%	41.62K	95K	41.62K	+100.00%
Jun 30, 2025	VIRTUS INVESTMENT ADVISERS, INC.	0.02%	41.61K	94.86K	-7.4K	-15.10%
Jun 30, 2025	SIVIA CAPITAL PARTNERS, LLC	0.02%	41.5K	94.62K	3.46K	+9.09%
Jun 30, 2025	SUSQUEHANNA PORTFOLIO STRATEGIES, LLC	0.02%	39.84K	90.83K	39.84K	+100.00%
Jun 30, 2025	FARTHER FINANCE ADVISORS, LLC	0.02%	38K	86.64K	5.69K	+17.60%
Jun 30, 2025	LOS ANGELES CAPITAL MANAGEMENT LLC	0.01%	30.4K	69.3K	30.4K	+100.00%
Jun 30, 2025	KOVITZ INVESTMENT GROUP PARTNERS, LLC	0.01%	25.21K	57.49K	0	0
Jun 30, 2025	ARIZONA STATE RETIREMENT SYSTEM	0.01%	22.63K	51.59K	-4.45K	-16.43%
Jun 30, 2025	BROWN ADVISORY INC	0.01%	20.85K	47.55K	0	0
Jun 30, 2025	QUADRATURE CAPITAL LTD	0.01%	18.46K	41.99K	18.46K	+100.00%
Jun 30, 2025	VANGUARD GROUP INC	3.91%	8.45M	19.28M	334.73K	+4.12%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.24%	530.08K	1.21B	62.53K	+13.37%
Jun 30, 2025	MORGAN STANLEY	0.18%	382.61K	872.36M	127.1K	+49.74%
Jun 30, 2025	WOODLINE PARTNERS LP	0.07%	155.86K	355.36K	-96.05K	-38.13%
Jun 30, 2025	ALLIANCEBERNSTEIN L.P.	0.06%	137.09K	312.57M	36.32K	+36.04%
Jun 30, 2025	VESTAL POINT CAPITAL, LP	5.09%	11.02M	25.11M	15K	+0.14%
Jun 30, 2025	BLACKROCK, INC.	4.52%	9.78M	22.29M	-170.74K	-1.72%
Jun 30, 2025	EMERALD ADVISERS, LLC	1.63%	3.53M	8.06M	444.16K	+14.37%
Jun 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	1.55%	3.35M	7.64M	-812.38K	-19.52%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.37%	2.97M	6.77M	147.95K	+5.24%
Jun 30, 2025	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.14%	309.84K	706.42K	-469.12K	-60.22%
Jun 30, 2025	TWO SIGMA INVESTMENTS, LP	0.13%	282.76K	644.7K	-122.84K	-30.29%
Jun 30, 2025	BANK OF NEW YORK MELLON CORP	0.12%	269.49K	614.43K	6.55K	+2.49%
Jun 30, 2025	BARCLAYS PLC	0.12%	253.83K	579K	92.35K	+57.19%
Jun 30, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.1%	221.67K	505.41K	62.62K	+39.37%
Jun 30, 2025	UBS GROUP AG	0.1%	216.61K	493.87K	32.35K	+17.56%
Jun 30, 2025	TWO SIGMA ADVISERS, LP	0.09%	199.32K	454.44K	-64.4K	-24.42%
Jun 30, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	0.08%	182.3K	415.64K	182.3K	+100.00%
Jun 30, 2025	ENTRYPOINT CAPITAL, LLC	0.08%	178.5K	406.98K	-3.16K	-1.74%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.07%	160.08K	364.98K	10.45K	+6.98%
Jun 30, 2025	STATE STREET CORP	1.14%	2.46M	5.6M	7.29K	+0.30%
Jun 30, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.61%	1.31M	2.99M	26.08K	+2.03%
Jun 30, 2025	SUPERSTRING CAPITAL MANAGEMENT LP	0.52%	1.12M	2.54M	149.18K	+15.44%
Jun 30, 2025	NORTHERN TRUST CORP	0.49%	1.07M	2.44M	13.48K	+1.28%
Jun 30, 2025	AXA S.A.	0.49%	1.05M	2.39M	1.69K	+0.16%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.46%	995.51K	2.27M	40.68K	+4.26%
Jun 30, 2025	DEUTSCHE BANK AG\	0.38%	831.05K	1.89M	-84.97K	-9.28%
Jun 30, 2025	ZURCHER KANTONALBANK (ZURICH CANTONALBANK)	0.07%	149.43K	340.69K	89.08K	+147.63%
Jun 30, 2025	SWISS NATIONAL BANK	0.07%	148.4K	338.35K	-29.6K	-16.63%
Jun 30, 2025	SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC	0.06%	123.36K	281.26K	-90.36K	-42.28%
Jun 30, 2025	UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH	0.05%	110K	250.8K	-27.69K	-20.11%
Mar 31, 2025	ENTRYPOINT CAPITAL, LLC	0.08%	181.66K	503.18K	78.37K	+75.87%
Mar 31, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	5.78%	11.46M	31.75M	2.8M	+32.35%
Mar 31, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.07%	159.05K	440.57K	2.07K	+1.32%
Mar 31, 2025	PRELUDE CAPITAL MANAGEMENT, LLC	0.12%	256.59K	710.77K	41.97K	+19.55%
Mar 31, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.37%	797.33K	2.21M	96.34K	+13.74%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.44%	954.83K	2.64M	-8.99K	-0.93%
Mar 31, 2025	TCG CROSSOVER MANAGEMENT, LLC	5.72%	12.36M	34.24M	0	0
Mar 31, 2025	DEUTSCHE BANK AG\	0.42%	916.02K	2.54M	-11.58K	-1.25%
Mar 31, 2025	VR ADVISER, LLC	1.64%	3.26M	9.02M	3.26M	+100.00%
Mar 31, 2025	BLACKROCK, INC.	4.6%	9.95M	27.55M	358.21K	+3.74%
Mar 31, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	8.88%	17.6M	48.75M	3.04M	+20.84%
Mar 31, 2025	RHUMBLINE ADVISERS	0.07%	153.54K	425.3K	12.12K	+8.57%
Mar 31, 2025	MORGAN STANLEY	0.12%	255.51K	707.77K	-140.45K	-35.47%
Mar 31, 2025	TWO SIGMA ADVISERS, LP	0.12%	263.72K	730.49K	-127K	-32.50%
Mar 31, 2025	DIMENSIONAL FUND ADVISORS LP	0.13%	288.67K	799.63K	145.01K	+100.94%
Mar 31, 2025		0.18%	385.1K	1.07M	385.1K	+100.00%
Mar 31, 2025	EXOME ASSET MANAGEMENT LLC	0.39%	836.4K	2.32M	136.7K	+19.54%
Mar 31, 2025	SUPERSTRING CAPITAL MANAGEMENT LP	0.45%	966.2K	2.68M	457.87K	+90.07%
Mar 31, 2025	TWO SIGMA INVESTMENTS, LP	0.19%	405.6K	1.12M	-379.87K	-48.36%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.22%	467.55K	1.3M	-198.94K	-29.85%
Mar 31, 2025	STATE STREET CORP	1.13%	2.45M	6.79M	-1.72M	-41.31%
Mar 31, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	0.69%	1.36M	3.77M	371.82K	+37.62%
Mar 31, 2025	NANTAHALA CAPITAL MANAGEMENT, LLC	4.07%	8.08M	22.37M	550.12K	+7.31%
Mar 31, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	4.02%	7.96M	22.06M	0	0
Mar 31, 2025	VANGUARD GROUP INC	3.76%	8.12M	22.49M	-190.72K	-2.30%
Mar 31, 2025	VESTAL POINT CAPITAL, LP	5.55%	11M	30.47M	225K	+2.09%
Mar 31, 2025	NEA MANAGEMENT COMPANY, LLC	11.32%	24.47M	67.79M	0	0
Mar 31, 2025	BANK OF NEW YORK MELLON CORP	0.12%	262.94K	728.33K	9.31K	+3.67%
Mar 31, 2025	FARALLON CAPITAL MANAGEMENT LLC	3.16%	6.84M	18.93M	0	0
Mar 31, 2025	UBS GROUP AG	0.09%	184.26K	510.39K	49.33K	+36.56%
Mar 31, 2025	BARCLAYS PLC	0.07%	161.48K	448K	-75.22K	-31.78%
Mar 31, 2025	SIO CAPITAL MANAGEMENT, LLC	0.36%	719.65K	1.99M	715.91K	+19,106.14%
Mar 31, 2025	JPMORGAN CHASE & CO	1.01%	2.18M	6.05M	760.52K	+53.44%
Mar 31, 2025	EMERALD MUTUAL FUND ADVISERS TRUST	0.93%	2.01M	5.58M	638.57K	+46.41%
Mar 31, 2025	WALLEYE CAPITAL LLC	0.1%	207.3K	574.22K	207.3K	+100.00%
Mar 31, 2025	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.36%	778.95K	2.16M	-58.51K	-6.99%
Mar 31, 2025	READYSTATE ASSET MANAGEMENT LP	0.24%	522.79K	1.45M	-7.53K	-1.42%
Mar 31, 2025	CITADEL ADVISORS LLC	0.23%	504.01K	1.4M	330.62K	+190.67%
Mar 31, 2025	ROSALIND ADVISORS, INC.	1.23%	2.65M	7.35M	0	0
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.31%	2.82M	7.82M	38.2K	+1.37%
Mar 31, 2025	EMERALD ADVISERS, LLC	1.43%	3.09M	8.56M	757.53K	+32.47%
Mar 31, 2025	SWISS NATIONAL BANK	0.08%	178K	493.06K	0	0
Mar 31, 2025	SOFINNOVA INVESTMENTS, INC.	2.77%	5.48M	15.18M	10.37K	+0.19%
Mar 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	1.93%	4.16M	11.53M	-1.32M	-24.06%
Mar 31, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.59%	1.28M	3.56M	72.62K	+5.99%
Mar 31, 2025	NORTHERN TRUST CORP	0.49%	1.06M	2.93M	-21.19K	-1.97%
Mar 31, 2025	AXA S.A.	0.49%	1.05M	2.9M	-1.33K	-0.13%
Mar 31, 2025	WOODLINE PARTNERS LP	0.12%	251.91K	697.8K	-2.44M	-90.62%
Mar 31, 2025	F/M INVESTMENTS LLC	0.1%	223.02K	617.75K	141.67K	+174.17%
Mar 31, 2025	SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC	0.1%	213.71K	591.99K	-14.82K	-6.49%
Mar 31, 2024	TWO SIGMA ADVISERS, LP	0.28%	499.12K	2.49M	462.9K	+1,278.20%
Mar 31, 2024	TWO SIGMA INVESTMENTS, LP	0.31%	562.19K	2.8M	426.34K	+313.85%
Mar 31, 2024	NORTHERN TRUST CORP	0.45%	803.16K	4M	8.25K	+1.04%
Mar 31, 2024	WALLEYE CAPITAL LLC	0.56%	1.03M	5.11M	936.91K	+1,053.59%
Mar 31, 2024	PRUDENTIAL FINANCIAL INC	0.62%	1.14M	5.67M	164.9K	+16.95%
Mar 31, 2024	AFFINITY ASSET ADVISORS, LLC	0.63%	1.15M	5.73M	0	0
Mar 31, 2024	ALTIUM CAPITAL MANAGEMENT LP	0.73%	1.34M	6.65M	2K	+0.15%
Mar 31, 2024	GHOST TREE CAPITAL, LLC	0.88%	1.6M	7.97M	850K	+113.33%
Mar 31, 2024	NANTAHALA CAPITAL MANAGEMENT, LLC	0.95%	1.74M	8.65M	749.51K	+75.87%
Mar 31, 2024	STATE STREET CORP	1.05%	1.88M	9.36M	112.01K	+6.34%
Mar 31, 2024	SUPERSTRING CAPITAL MANAGEMENT LP	1.13%	2.07M	10.28M	1.25M	+153.62%
Mar 31, 2024	VIVO CAPITAL, LLC	1.14%	2.09M	10.4M	0	0
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	1.32%	2.37M	11.79M	40.93K	+1.76%
Mar 31, 2024	JANUS HENDERSON GROUP PLC	1.4%	2.56M	12.75M	746.41K	+41.07%
Mar 31, 2024	WELLINGTON MANAGEMENT GROUP LLP	1.55%	2.78M	13.84M	719.01K	+34.90%
Mar 31, 2024	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	2.19%	4M	19.92M	0	0
Mar 31, 2024	VANGUARD GROUP INC	3.37%	6.06M	30.2M	148.67K	+2.51%
Mar 31, 2024	ADAGE CAPITAL PARTNERS GP, L.L.C.	4.54%	8.29M	41.27M	650K	+8.51%
Mar 31, 2024	NEA MANAGEMENT COMPANY, LLC	13.41%	24.47M	121.87M	0	0
Mar 31, 2024	BLACKROCK INC.	4.03%	7.24M	36.06M	-19.72K	-0.27%
Mar 31, 2024	JENNISON ASSOCIATES LLC	4.84%	8.84M	44.03M	26.61K	+0.30%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.09%	162.21K	807.82K	0	0
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.05%	88.55K	440.97K	55.85K	+170.78%
Mar 31, 2024	FARALLON CAPITAL MANAGEMENT LLC	1.31%	2.39M	11.92M	-3.86M	-61.72%
Mar 31, 2024	DEUTSCHE BANK AG\	0.42%	753.89K	3.75M	720.72K	+2,173.13%
Mar 31, 2024	OPALEYE MANAGEMENT INC.	0.47%	855K	4.26M	855K	+100.00%
Mar 31, 2024	SOFINNOVA INVESTMENTS, INC.	1.29%	2.35M	11.69M	-35.57K	-1.49%
Mar 31, 2024	CITIGROUP INC	0.01%	17.32K	86.25K	2K	+13.07%
Mar 31, 2024	ARIZONA STATE RETIREMENT SYSTEM	0.01%	20.47K	101.94K	20.47K	+100.00%
Mar 31, 2024	BROWN ADVISORY INC	0.01%	20.85K	103.85K	0	0
Mar 31, 2024	STRS OHIO	0.01%	22.8K	113K	22.8K	+100.00%
Mar 31, 2024	KOVITZ INVESTMENT GROUP PARTNERS, LLC	0.01%	25.21K	125.57K	25.21K	+100.00%
Mar 31, 2024	PROSHARE ADVISORS LLC	0.01%	25.72K	128.06K	2.11K	+8.96%
Mar 31, 2024	FARTHER FINANCE ADVISORS, LLC	0.01%	25.78K	124.79K	0	0
Mar 31, 2024	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.01%	26.04K	130K	10.38K	+66.32%
Mar 31, 2024	HARVEST INVESTMENT SERVICES, LLC	0.02%	28.72K	143.05K	28.72K	+100.00%
Mar 31, 2024	NEW YORK STATE COMMON RETIREMENT FUND	0.02%	30.46K	152K	12.44K	+69.08%
Mar 31, 2024	BELVEDERE TRADING LLC	0.02%	33.6K	167.33K	33.6K	+100.00%
Mar 31, 2024	WELLS FARGO & COMPANY/MN	0.02%	33.67K	167.65K	3.57K	+11.85%
Mar 31, 2024	SG AMERICAS SECURITIES, LLC	0.02%	33.72K	168K	-16.15K	-32.38%
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	0.02%	34.1K	169.82K	11.59K	+51.49%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.02%	35.92K	178.86K	0	0
Mar 31, 2024	SIVIA CAPITAL PARTNERS, LLC	0.02%	37.5K	186.75K	1.5K	+4.17%
Mar 31, 2024	METLIFE INVESTMENT MANAGEMENT, LLC	0.02%	39.81K	198.26K	-8.81K	-18.11%
Mar 31, 2024	INVESCO LTD.	0.02%	43.21K	215.19K	-59.78K	-58.04%
Mar 31, 2024	AMERICAN INTERNATIONAL GROUP, INC.	0.02%	44.52K	221.71K	-383	-0.85%
Mar 31, 2024	STATE OF WISCONSIN INVESTMENT BOARD	0.03%	55K	273.91K	55K	+100.00%
Mar 31, 2024	JUMP FINANCIAL, LLC	0.04%	63.88K	318.1K	-72.82K	-53.27%
Mar 31, 2024	LEGAL & GENERAL GROUP PLC	0.04%	64.01K	318.79M	56.51K	+752.50%
Mar 31, 2024	NEW YORK LIFE INVESTMENT MANAGEMENT LLC	0.04%	72.62K	361.67K	72.62K	+100.00%
Mar 31, 2024	BNP PARIBAS ARBITRAGE, SNC	0.04%	73.49K	366K	35.27K	+92.27%
Mar 31, 2024	SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC	0.04%	79.07K	393.78K	79.07K	+100.00%
Mar 31, 2024	CREDIT SUISSE AG/	0.05%	90.71K	451.71K	90.71K	+100.00%
Mar 31, 2024	ALPS ADVISORS INC	0.05%	95.46K	475.4K	4.54K	+5.00%
Mar 31, 2024	AWM INVESTMENT COMPANY, INC.	0.05%	100K	498K	100K	+100.00%
Mar 31, 2024	UBS GROUP AG	0.06%	108.69K	541.26K	2.45K	+2.31%
Mar 31, 2024	OPTIONS SOLUTIONS, LLC	0.06%	110.67K	551.13K	110.67K	+100.00%
Mar 31, 2024	QUBE RESEARCH & TECHNOLOGIES LTD	0.07%	120.94K	602.29K	-4.81K	-3.82%
Mar 31, 2024	RHUMBLINE ADVISERS	0.07%	133.93K	666.96K	3.87K	+2.97%
Mar 31, 2024	DIMENSIONAL FUND ADVISORS LP	0.08%	138.21K	688.29K	-7.06K	-4.86%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.08%	144.88K	721.5K	17.68K	+13.90%
Mar 31, 2024	SWISS NATIONAL BANK	0.08%	147K	732.06K	147K	+100.00%
Mar 31, 2024	JPMORGAN CHASE & CO	0.09%	166.99K	831.62K	80.65K	+93.41%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.09%	169.23K	842.74K	89.02K	+111.00%
Mar 31, 2024	SCHONFELD STRATEGIC ADVISORS LLC	0.1%	177.1K	881.96K	156.5K	+759.71%
Mar 31, 2024	ALGERT GLOBAL LLC	0.11%	197.43K	983K	197.43K	+100.00%
Mar 31, 2024	MORGAN STANLEY	0.13%	231.56K	1.15M	10.05K	+4.54%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.13%	242.58K	1.21M	-5.99K	-2.41%
Mar 31, 2024	CLARIVEST ASSET MANAGEMENT LLC	0.14%	249.31K	1.24M	467	+0.19%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.14%	256.18K	1.28M	-39.52K	-13.36%
Mar 31, 2024	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.22%	392.72K	1.96M	124.28K	+46.29%
Mar 31, 2024	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.59%	1.09M	5.41M	1.09M	+100.00%
Mar 31, 2024	AXA S.A.	0.73%	1.33M	6.63M	-417.24K	-23.87%
Mar 31, 2024	TCG CROSSOVER MANAGEMENT, LLC	5.48%	10M	49.8M	0	0
Mar 31, 2024	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	7.98%	14.57M	72.54M	332.71K	+2.34%
Dec 31, 2023	VR ADVISER, LLC	2.13%	3.5M	16.45M	-3.68M	-51.29%
Dec 31, 2023	SOFINNOVA INVESTMENTS, INC.	1.45%	2.38M	11.2M	2.22M	+1,409.00%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.42%	2.33M	10.94M	105.39K	+4.74%
Dec 31, 2023	RENAISSANCE TECHNOLOGIES LLC	0.16%	256.9K	1.21M	153K	+147.26%
Dec 31, 2023	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.16%	268.45K	1.26M	42.22K	+18.66%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.18%	295.7K	1.39M	34.27K	+13.11%
Dec 31, 2023	CAXTON CORP	0.22%	353.44K	1.66M	-2.96M	-89.33%
Dec 31, 2023	VIVO CAPITAL, LLC	1.27%	2.09M	9.82M	174.97K	+9.14%
Dec 31, 2023	BLACKROCK INC.	4.42%	7.26M	34.13M	1.22M	+20.23%
Dec 31, 2023	ADAGE CAPITAL PARTNERS GP, L.L.C.	4.65%	7.64M	35.9M	-300.62K	-3.79%
Dec 31, 2023	JENNISON ASSOCIATES LLC	5.36%	8.82M	41.43M	4.95M	+127.98%
Dec 31, 2023	TCG CROSSOVER MANAGEMENT, LLC	6.08%	10M	47M	0	0
Dec 31, 2023	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	8.66%	14.23M	66.89M	0	0
Dec 31, 2023	NEA MANAGEMENT COMPANY, LLC	14.89%	24.47M	115.01M	0	0
Dec 31, 2023	SG AMERICAS SECURITIES, LLC	0.03%	49.86K	234K	12.72K	+34.25%
Dec 31, 2023	JANE STREET GROUP, LLC	0.04%	60.46K	284.15K	60.46K	+100.00%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.05%	80.2K	376.94K	-17.37K	-17.80%
Dec 31, 2023	JPMORGAN CHASE & CO	0.05%	86.34K	405.81K	24.76K	+40.20%
Dec 31, 2023	WALLEYE CAPITAL LLC	0.05%	88.93K	417.95K	88.93K	+100.00%
Dec 31, 2023	ALPS ADVISORS INC	0.06%	90.92K	427.32K	90.92K	+100.00%
Dec 31, 2023	INVESCO LTD.	0.06%	102.99K	484.05K	32.48K	+46.06%
Dec 31, 2023	UBS GROUP AG	0.06%	106.24K	499.31K	51.77K	+95.03%
Dec 31, 2023	BARCLAYS PLC	0.08%	123.96K	582K	107.93K	+673.37%
Dec 31, 2023	QUBE RESEARCH & TECHNOLOGIES LTD	0.08%	125.75K	591.02K	125.75K	+100.00%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.08%	127.2K	597.84K	38.9K	+44.05%
Dec 31, 2023	RHUMBLINE ADVISERS	0.08%	130.06K	611.29K	8.53K	+7.02%
Dec 31, 2023	TWO SIGMA INVESTMENTS, LP	0.08%	135.84K	638.46K	135.84K	+100.00%
Dec 31, 2023	JUMP FINANCIAL, LLC	0.08%	136.7K	642.49K	104.17K	+320.28%
Dec 31, 2023	DIMENSIONAL FUND ADVISORS LP	0.09%	145.28K	682.79K	-18.87K	-11.50%
Dec 31, 2023	NUVEEN ASSET MANAGEMENT, LLC	0.1%	162.21K	762.4K	0	0
Dec 31, 2023	CITADEL ADVISORS LLC	0.1%	169.94K	798.72K	150.36K	+767.70%
Dec 31, 2023	UBS OCONNOR LLC	0.11%	176.89K	831.36K	-203.47K	-53.49%
Dec 31, 2023	WELLINGTON MANAGEMENT GROUP LLP	1.25%	2.06M	9.68M	2.06M	+100.00%
Dec 31, 2023	JANUS HENDERSON GROUP PLC	1.11%	1.82M	8.55M	-183.29K	-9.16%
Dec 31, 2023	STATE STREET CORP	1.08%	1.77M	8.31M	230.74K	+15.01%
Dec 31, 2023	AXA S.A.	1.06%	1.75M	8.21M	-42.28K	-2.36%
Dec 31, 2023	ALTIUM CAPITAL MANAGEMENT LP	0.81%	1.33M	6.27M	1.33M	+100.00%
Dec 31, 2023	AFFINITY ASSET ADVISORS, LLC	0.7%	1.15M	5.41M	0	0
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	0.63%	1.04M	4.9M	1.04M	+100.00%
Dec 31, 2023	NANTAHALA CAPITAL MANAGEMENT, LLC	0.6%	987.9K	4.64M	-51.46K	-4.95%
Dec 31, 2023	PRUDENTIAL FINANCIAL INC	0.59%	972.95K	4.57M	593.01K	+156.08%
Dec 31, 2023		0.5%	814.27K	3.83M	814.27K	+100.00%
Dec 31, 2023	NORTHERN TRUST CORP	0.48%	794.91K	3.74M	47.92K	+6.41%
Dec 31, 2023	MORGAN STANLEY	0.13%	221.51K	1.04M	145.58K	+191.74%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.15%	248.56K	1.17M	0	0
Dec 31, 2023	CLARIVEST ASSET MANAGEMENT LLC	0.15%	248.84K	1.17M	5.94K	+2.45%
Dec 31, 2023	GHOST TREE CAPITAL, LLC	0.46%	750K	3.53M	750K	+100.00%
Dec 31, 2023	FARALLON CAPITAL MANAGEMENT LLC	3.81%	6.26M	29.4M	-4.65M	-42.65%
Dec 31, 2023	VANGUARD GROUP INC	3.6%	5.91M	27.8M	150.35K	+2.61%
Dec 31, 2023	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	2.43%	4M	18.8M	0	0

Insiders

Among the SVRA insiders holding of 2.33% of the stake in company, YANG RICK, 10 percent owner, holds the largest shares of 24.47M. WALKER PAUL EDWARD, 10 percent owner, is the second largest SVRA insider with ownership of 24.47M shares. BEHBAHANI ALI, 10 percent owner, stands third with possession of 24.47M shares of that stake.

Insiders	Designation	Shares Held
YANG RICK	10 percent owner	24.47M
WALKER PAUL EDWARD	10 percent owner	24.47M
BEHBAHANI ALI	10 percent owner	24.47M
SANDELL SCOTT D	10 percent owner	24.47M
MATHERS EDWARD T	10 percent owner	24.47M
CHANG CARMEN	10 percent owner	24.47M
MAKHZOUMI MOHAMAD	10 percent owner	24.47M
FLORENCE ANTHONY A. JR.	10 percent owner	24.47M
BASKETT FOREST	10 percent owner	24.47M
GROWTH EQUITY OPPORTUNITIES 17, LLC	10 percent owner	24.47M
RAMSAY DAVID A	director	2.53M
PAULS MATTHEW	CHIEF EXECUTIVE OFFICER	1.54M
LOWRANCE DAVID L	Chief Financial Officer	381.01K
MCCRACKEN JOSEPH S	director	260.84K
CHOWDHURY BADRUL A.	CHIEF MEDICAL OFFICER	175K
PRATT RAYMOND DENNIS	Chief Medical Officer	160K
HAWKINS RICHARD J	director	115.47K
ELAM NEVAN C	director	22.5K

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Dec 19, 2025	RAMSAY DAVID A	SALE	6.06	20K	121.22K	2.53M
Jun 20, 2025	HAWKINS RICHARD J	PURCHASE	2.04	48.23K	98.57K	115.47K
May 29, 2025	MCCRACKEN JOSEPH S	PURCHASE	2.08	10K	20.83K	260.84K
Mar 31, 2025	RAMSAY DAVID A	PURCHASE	2.77	150K	416.25K	2.51M
Dec 16, 2024	HAWKINS RICHARD J	SALE	3.32	8K	26.57K	67.24K
Dec 16, 2024	PAULS MATTHEW	SALE	3.31	54.7K	180.83K	1.54M
Dec 16, 2024	LOWRANCE DAVID L	SALE	3.33	25K	83.28K	381.01K
Nov 19, 2024	MCCRACKEN JOSEPH S	PURCHASE	2.95	20K	59.07K	210.84K
Nov 18, 2024	RAMSAY DAVID A	PURCHASE	2.88	100K	287.6K	2.32M
Dec 28, 2023	PAULS MATTHEW	SALE	4.71	84K	395.9K	1.3M
Dec 28, 2023	ELAM NEVAN C	SALE	4.71	93.84K	442.29K	22.5K
Dec 28, 2023	LOWRANCE DAVID L	SALE	4.71	10K	47.13K	342.36K
Jul 17, 2023	WALKER PAUL EDWARD	PURCHASE	3.00	333.33K	1M	24.47M
Jul 17, 2023	BEHBAHANI ALI	PURCHASE	3.00	333.33K	1M	24.47M
Jul 17, 2023	YANG RICK	PURCHASE	3.00	333.33K	1M	24.47M
Jul 17, 2023	FLORENCE ANTHONY A. JR.	PURCHASE	3.00	333.33K	1M	24.47M
Jul 17, 2023	MAKHZOUMI MOHAMAD	PURCHASE	3.00	333.33K	1M	24.47M
Jul 17, 2023	SANDELL SCOTT D	PURCHASE	3.00	333.33K	1M	24.47M
Jul 17, 2023	GROWTH EQUITY OPPORTUNITIES 17, LLC	PURCHASE	3.00	333.33K	1M	24.47M
Jul 17, 2023	BASKETT FOREST	PURCHASE	3.00	333.33K	1M	24.47M
Jul 17, 2023	MATHERS EDWARD T	PURCHASE	3.00	333.33K	1M	24.47M
Jul 17, 2023	CHANG CARMEN	PURCHASE	3.00	333.33K	1M	24.47M
Jun 26, 2023	PRATT RAYMOND DENNIS	PURCHASE	2.93	6.5K	19.05K	160K
May 26, 2023	RAMSAY DAVID A	PURCHASE	2.63	37.12K	97.6K	2.2M
May 25, 2023	RAMSAY DAVID A	PURCHASE	2.57	12.88K	33.13K	2.16M
May 24, 2023	RAMSAY DAVID A	PURCHASE	2.56	50K	127.8K	2.15M
Dec 30, 2022	RAMSAY DAVID A	PURCHASE	1.55	29K	44.83K	2.1M
Dec 29, 2022	RAMSAY DAVID A	PURCHASE	1.54	7K	10.75K	2.07M
Dec 28, 2022	RAMSAY DAVID A	PURCHASE	1.50	3.29K	4.92K	2.07M
Dec 23, 2022	RAMSAY DAVID A	PURCHASE	1.44	15.71K	22.67K	2.06M
Dec 22, 2022	PRATT RAYMOND DENNIS	PURCHASE	1.54	3.5K	5.4K	153.5K
Dec 22, 2022	RAMSAY DAVID A	PURCHASE	1.48	41.41K	61.13K	2.05M
Dec 20, 2022	RAMSAY DAVID A	PURCHASE	1.50	13.83K	20.76K	2M
Dec 19, 2022	RAMSAY DAVID A	PURCHASE	1.49	40.72K	60.83K	1.99M
Dec 16, 2022	RAMSAY DAVID A	PURCHASE	1.50	341	511.5	1.95M
Nov 23, 2022	RAMSAY DAVID A	PURCHASE	1.44	4.61K	6.63K	1.95M
Nov 22, 2022	RAMSAY DAVID A	PURCHASE	1.42	15.5K	22.02K	1.94M
Nov 21, 2022	RAMSAY DAVID A	PURCHASE	1.42	25.01K	35.53K	1.93M
Nov 18, 2022	RAMSAY DAVID A	PURCHASE	1.34	16.1K	21.61K	1.9M
Nov 17, 2022	RAMSAY DAVID A	PURCHASE	1.27	8.9K	11.3K	1.89M
Sep 27, 2022	RAMSAY DAVID A	PURCHASE	1.37	73.89K	101.38K	1.88M
Sep 26, 2022	RAMSAY DAVID A	PURCHASE	1.38	31.11K	43.05K	1.8M
Sep 23, 2022	RAMSAY DAVID A	PURCHASE	1.42	30K	42.66K	1.77M
Sep 20, 2022	RAMSAY DAVID A	PURCHASE	1.45	600	870	1.74M
Sep 19, 2022	RAMSAY DAVID A	PURCHASE	1.46	1.4K	2.04K	1.74M
Sep 16, 2022	RAMSAY DAVID A	PURCHASE	1.44	6K	8.65K	1.74M
Sep 08, 2022	RAMSAY DAVID A	PURCHASE	1.40	29K	40.57K	1.73M
Sep 07, 2022	RAMSAY DAVID A	PURCHASE	1.39	2.13K	2.95K	1.7M
Sep 06, 2022	RAMSAY DAVID A	PURCHASE	1.38	870	1.2K	1.7M
Sep 01, 2022	RAMSAY DAVID A	PURCHASE	1.42	39.77K	56.47K	1.7M
Aug 31, 2022	RAMSAY DAVID A	PURCHASE	1.42	39.49K	56.2K	1.66M
Aug 30, 2022	RAMSAY DAVID A	PURCHASE	1.41	20.74K	29.26K	1.62M
Jun 21, 2022	RAMSAY DAVID A	PURCHASE	1.38	21.09K	29.11K	1.56M
Jun 17, 2022	RAMSAY DAVID A	PURCHASE	1.33	39.91K	52.92K	1.54M
Dec 30, 2021	RAMSAY DAVID A	PURCHASE	1.30	35K	45.36K	1.5M
Dec 29, 2021	RAMSAY DAVID A	PURCHASE	1.25	15K	18.68K	1.47M
Dec 17, 2021	RAMSAY DAVID A	PURCHASE	1.13	25K	28.23K	1.45M
Dec 17, 2021	LOWRANCE DAVID L	PURCHASE	1.14	4K	4.57K	142.79K
Dec 15, 2021	RAMSAY DAVID A	PURCHASE	1.08	15K	16.26K	1.43M
Dec 10, 2021	RAMSAY DAVID A	PURCHASE	1.04	35K	36.37K	1.41M
Dec 09, 2021	CHOWDHURY BADRUL A.	PURCHASE	1.05	25K	26.25K	175K
Dec 08, 2021	PAULS MATTHEW	PURCHASE	1.06	6.5K	6.89K	383.67K
Dec 08, 2021	RAMSAY DAVID A	PURCHASE	1.05	13.16K	13.81K	1.38M
Dec 07, 2021	RAMSAY DAVID A	PURCHASE	1.05	11.84K	12.4K	1.36M
Dec 02, 2021	PAULS MATTHEW	PURCHASE	1.10	10K	10.95K	377.17K
Dec 02, 2021	RAMSAY DAVID A	PURCHASE	1.09	21.39K	23.23K	1.35M
Dec 01, 2021	RAMSAY DAVID A	PURCHASE	1.08	9K	9.77K	1.33M
Nov 30, 2021	RAMSAY DAVID A	PURCHASE	1.09	16K	17.39K	1.32M
Nov 22, 2021	RAMSAY DAVID A	PURCHASE	1.08	90K	97.02K	1.3M
Nov 19, 2021	PAULS MATTHEW	PURCHASE	1.11	10K	11.1K	365.02K
Nov 19, 2021	RAMSAY DAVID A	PURCHASE	1.07	49.8K	53.24K	1.21M
Nov 18, 2021	RAMSAY DAVID A	PURCHASE	1.08	60.2K	65.14K	1.16M
Nov 18, 2021	PAULS MATTHEW	PURCHASE	1.10	10K	11K	355.02K
Sep 30, 2021	RAMSAY DAVID A	PURCHASE	1.30	50K	64.9K	1.1M
Sep 29, 2021	RAMSAY DAVID A	PURCHASE	1.28	47.5K	60.66K	1.05M
Sep 28, 2021	RAMSAY DAVID A	PURCHASE	1.28	39.55K	50.82K	1M
Aug 18, 2021	PAULS MATTHEW	PURCHASE	1.19	11.9K	14.17K	345.02K
Aug 18, 2021	RAMSAY DAVID A	PURCHASE	1.18	12.95K	15.28K	946.3K
Aug 17, 2021	RAMSAY DAVID A	PURCHASE	1.18	66.55K	78.2K	933.35K
Aug 17, 2021	PAULS MATTHEW	PURCHASE	1.18	15K	17.7K	333.12K
May 21, 2021	PAULS MATTHEW	PURCHASE	1.63	10K	16.3K	318.12K
May 19, 2021	RAMSAY DAVID A	PURCHASE	1.58	5K	7.9K	866.8K
May 18, 2021	RAMSAY DAVID A	PURCHASE	1.62	50K	81.1K	861.8K
May 17, 2021	CHOWDHURY BADRUL A.	SALE	1.56	50K	77.87K	150K
Apr 19, 2021	PAULS MATTHEW	PURCHASE	1.82	27.4K	49.87K	308.12K
Mar 22, 2021	PAULS MATTHEW	PURCHASE	2.07	24.1K	49.94K	280.72K
Mar 15, 2021	MCCRACKEN JOSEPH S	PURCHASE	1.45	68.97K	100K	168.34K
Mar 15, 2021	RAMSAY DAVID A	PURCHASE	1.45	689.66K	1M	811.8K
Mar 15, 2021	LOWRANCE DAVID L	PURCHASE	1.45	13.79K	20K	13.79K
Feb 22, 2021	PAULS MATTHEW	PURCHASE	1.74	28.7K	50.04K	256.62K
Jun 28, 2019	RAMSAY DAVID A	PURCHASE	2.33	18K	41.94K	104.99K
Jun 27, 2019	RAMSAY DAVID A	PURCHASE	2.45	5K	12.25K	69.69K
Jun 26, 2019	RAMSAY DAVID A	PURCHASE	2.38	900	2.14K	64.69K
Jun 18, 2019	RAMSAY DAVID A	PURCHASE	2.36	5K	11.8K	53.57K
Jun 17, 2019	RAMSAY DAVID A	PURCHASE	2.38	10K	23.8K	43.57K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES20K1

NET SHARES-20K1

SHARES HELD2.53M1

% NET SHARES-100.79%0%

Frequently Asked Questions

Stock Outstanding Shares

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares10.2

Short Percent Of Float12.24

Shares Outstanding172.84M

Shares Float86.68M

Shares Short17.63M

Short Ratio16.62

12.24%

Short % of Float

10.2%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

2.33% Percentage of Shares held by All Insiders

97.78% Percentage of Shares held by All Institutions

100.12% Percentage of Float held by Institutions

201

Number of Institutions Holding Shares

Institutional Ownership

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Dec 31, 2025		0.28%	605.28K	3.65M	605.28K	+100.00%
Dec 31, 2025	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.02%	33.16K	199.93K	2.86K	+9.44%
Dec 31, 2025	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0.02%	33.93K	204.57K	0	0
Dec 31, 2025	PROSHARE ADVISORS LLC	0.02%	34.87K	210.26K	9.13K	+35.49%
Dec 31, 2025	PROFUND ADVISORS LLC	0.02%	35.15K	211.92K	35.15K	+100.00%
Dec 31, 2025	DEUTSCHE BANK AG\	0.38%	824.72K	4.97M	-26.26K	-3.09%
Dec 31, 2025	SIREN, L.L.C.	0.46%	1M	6.03M	1M	+100.00%
Dec 31, 2025	MORGAN STANLEY	1.08%	2.34M	14.1M	420.07K	+21.90%
Dec 31, 2025	VIRTUS INVESTMENT ADVISERS, INC.	0.02%	38.44K	231.81K	-11.91K	-23.65%
Dec 31, 2025	ENTRYPOINT CAPITAL, LLC	0.02%	40.72K	245.52K	-40.93K	-50.13%
Dec 31, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.02%	40.96K	246.98K	-5.35K	-11.54%
Dec 31, 2025	CITADEL ADVISORS LLC	0.36%	774.49K	4.67M	106.39K	+15.92%
Dec 31, 2025	SWEDBANK AB	0.39%	850K	5.13M	300K	+54.55%
Dec 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.54%	1.16M	7M	197.87K	+20.53%
Dec 31, 2025	NAN FUNG TRINITY (HK) LTD	0.78%	1.69M	10.18M	1.69M	+100.00%
Dec 31, 2025	EMERALD MUTUAL FUND ADVISERS TRUST	1.11%	2.4M	14.45M	245.1K	+11.39%
Dec 31, 2025	AFFINITY ASSET ADVISORS, LLC	1.29%	2.8M	16.87M	1.3M	+86.48%
Dec 31, 2025	ROSALIND ADVISORS, INC.	1.57%	3.4M	20.52M	-596.28K	-14.91%
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.58%	3.42M	20.61M	622.11K	+22.25%
Dec 31, 2025	EMERALD ADVISERS, LLC	1.61%	3.5M	21.08M	-33.83K	-0.96%
Dec 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0.15%	332.1K	2M	72K	+27.68%
Dec 31, 2025	SUMMITTX CAPITAL, L.P.	0.17%	373.03K	2.25M	373.03K	+100.00%
Dec 31, 2025	BANK OF AMERICA CORP /DE/	0.2%	423.6K	2.55M	303.61K	+253.03%
Dec 31, 2025	GOLDMAN SACHS GROUP INC	0.24%	516.6K	3.12M	-145.65K	-21.99%
Dec 31, 2025	D. E. SHAW & CO., INC.	0.77%	1.67M	10.07M	1.3M	+348.73%
Dec 31, 2025	PERCEPTIVE ADVISORS LLC	1.11%	2.4M	14.47M	2.4M	+100.00%
Dec 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	1.24%	2.67M	16.13M	30.93K	+1.17%
Dec 31, 2025	WOODLINE PARTNERS LP	1.96%	4.24M	25.6M	4.01M	+1,689.32%
Dec 31, 2025	RTW INVESTMENTS, LP	2.75%	5.95M	35.89M	5.95M	+100.00%
Dec 31, 2025	POLAR CAPITAL HOLDINGS PLC	3.84%	8.31M	50.09M	8.31M	+100.00%
Dec 31, 2025	TCG CROSSOVER MANAGEMENT, LLC	5.71%	12.36M	74.54M	0	0
Dec 31, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	6.27%	13.57M	81.82M	5.61M	+70.38%
Dec 31, 2025	MILLENNIUM MANAGEMENT LLC	0.25%	534.97K	3.23M	-309.21K	-36.63%
Dec 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.25%	543.76K	3.28M	522.39K	+2,445.20%
Dec 31, 2025	JANE STREET GROUP, LLC	0.27%	584.29K	3.52M	-21.28K	-3.51%
Dec 31, 2025	STATE STREET CORP	2%	4.33M	26.13M	1.97M	+83.61%
Dec 31, 2025	SIO CAPITAL MANAGEMENT, LLC	0.28%	613.89K	3.7M	-112.96K	-15.54%
Dec 31, 2025	F/M INVESTMENTS LLC	0.31%	678.81K	4.09M	245.1K	+56.51%
Dec 31, 2025	INVESCO LTD.	0.32%	688.6K	4.15M	517.33K	+302.06%
Dec 31, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.35%	751.26K	4.53M	-105.35K	-12.30%
Dec 31, 2025	SUPERSTRING CAPITAL MANAGEMENT LP	0.46%	995.35K	6M	-313.88K	-23.97%
Dec 31, 2025	NORTHERN TRUST CORP	0.5%	1.08M	6.5M	130.89K	+13.83%
Dec 31, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.54%	1.18M	7.1M	-172.17K	-12.75%
Dec 31, 2025	VR ADVISER, LLC	6.35%	13.74M	82.85M	1.06M	+8.35%
Dec 31, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	8.13%	17.6M	106.13M	0	0
Dec 31, 2025	NEA MANAGEMENT COMPANY, LLC	11.31%	24.47M	147.56M	0	0
Dec 31, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.02%	43.55K	262.59K	5.08K	+13.21%
Dec 31, 2025	SG AMERICAS SECURITIES, LLC	0.02%	45.53K	275K	45.53K	+100.00%
Dec 31, 2025	DYMON ASIA CAPITAL (SINGAPORE) PTE. LTD.	0.02%	46K	277.38K	46K	+100.00%
Dec 31, 2025	SIVIA CAPITAL PARTNERS, LLC	0.02%	48.51K	292.5K	7	+0.01%
Dec 31, 2025	BANK OF NOVA SCOTIA	0.02%	51.7K	311.75K	51.7K	+100.00%
Dec 31, 2025	JUMP FINANCIAL, LLC	0.03%	70.7K	426.29K	70.7K	+100.00%
Dec 31, 2025	JPMORGAN CHASE & CO	0.03%	73.06K	440.55K	9.22K	+14.45%
Dec 31, 2025	OXFORD ASSET MANAGEMENT LLP	0.03%	74.12K	446.91K	74.12K	+100.00%
Dec 31, 2025	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.03%	74.88K	451.54K	-18.99K	-20.23%
Dec 31, 2025	LONGAEVA PARTNERS L.P.	0.58%	1.25M	7.51M	1.25M	+100.00%
Dec 31, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	0.65%	1.41M	8.47M	-582.84K	-29.31%
Dec 31, 2025	VESTAL POINT CAPITAL, LP	0.74%	1.61M	9.68M	-2.41M	-60.00%
Dec 31, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.04%	78.55K	473.66K	18.25K	+30.25%
Dec 31, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.04%	89.86K	541.84K	89.86K	+100.00%
Dec 31, 2025	UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH	0.04%	90K	549.9K	-20K	-18.18%
Dec 31, 2025	GSA CAPITAL PARTNERS LLP	0.07%	140.75K	849K	-231.7K	-62.21%
Dec 31, 2025	WALLEYE CAPITAL LLC	0.07%	150.08K	905.01K	59.06K	+64.89%
Dec 31, 2025	RHUMBLINE ADVISERS	0.07%	152.78K	921.23M	-4.79K	-3.04%
Dec 31, 2025	WELLS FARGO & COMPANY/MN	0.08%	167.64K	1.01M	83.55K	+99.36%
Dec 31, 2025	DIMENSIONAL FUND ADVISORS LP	0.08%	170.13K	1.03M	-530.52K	-75.72%
Dec 31, 2025	UBS GROUP AG	0.09%	202.88K	1.22M	-492.85K	-70.84%
Dec 31, 2025	NUVEEN, LLC	0.13%	272.6K	1.64M	35.77K	+15.10%
Dec 31, 2025	SOFINNOVA INVESTMENTS, INC.	0.14%	304.77K	1.84M	-2.12M	-87.45%
Dec 31, 2025	BARCLAYS PLC	0.14%	306.94K	1.85M	130.42K	+73.89%
Dec 31, 2025	MARSHALL WACE, LLP	2.11%	4.56M	27.5M	4.56M	+100.00%
Dec 31, 2025	STRS OHIO	0.01%	26.5K	159.8K	26.5K	+100.00%
Dec 31, 2025	FARTHER FINANCE ADVISORS, LLC	0.01%	26.9K	162.18K	-2.28K	-7.81%
Dec 31, 2025	NANTAHALA CAPITAL MANAGEMENT, LLC	3.39%	7.34M	44.29M	-1.43M	-16.30%
Dec 31, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	4.56%	9.86M	59.47M	-1.6M	-13.96%
Dec 31, 2025	VANGUARD GROUP INC	4.64%	10.04M	60.55M	1.73M	+20.79%
Dec 31, 2025	BLACKROCK, INC.	5.13%	11.1M	66.92M	2.65M	+31.36%
Dec 31, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.02%	36.56K	220.43K	22.7K	+163.84%
Dec 31, 2025	SKOPOS LABS, INC.	0.02%	36.81K	233K	-61.83K	-62.68%
Dec 31, 2025	BANK OF NEW YORK MELLON CORP	0.14%	312.87K	1.89M	39.51K	+14.46%
Dec 31, 2025	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	0.49%	1.06M	6.4M	1.06M	+100.00%
Dec 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.01%	31.2K	188.16K	6.05K	+24.05%
Sep 30, 2025	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.04%	93.87K	335.11K	-215.97K	-69.70%
Sep 30, 2025	SKOPOS LABS, INC.	0.05%	98.64K	218K	20.73K	+26.61%
Sep 30, 2025	ALLIANCEBERNSTEIN L.P.	0.05%	118.79K	424.08K	-18.3K	-13.35%
Sep 30, 2025	MORGAN STANLEY	0.89%	1.92M	6.85M	1.54M	+401.24%
Sep 30, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	0.92%	1.99M	7.1M	-1.61M	-44.78%
Sep 30, 2025	STATE STREET CORP	1.09%	2.36M	8.42M	-97.08K	-3.95%
Sep 30, 2025	SOFINNOVA INVESTMENTS, INC.	1.12%	2.43M	8.67M	-29.63K	-1.21%
Sep 30, 2025	FARALLON CAPITAL MANAGEMENT LLC	1.16%	2.5M	8.93M	-4.34M	-63.42%
Sep 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	1.22%	2.64M	9.44M	-706.27K	-21.08%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.29%	2.8M	9.98M	-174.52K	-5.88%
Sep 30, 2025	EMERALD ADVISERS, LLC	1.63%	3.53M	12.6M	-5.04K	-0.14%
Sep 30, 2025	EMERALD MUTUAL FUND ADVISERS TRUST	0.99%	2.15M	7.68M	-35.05K	-1.60%
Sep 30, 2025	ROSALIND ADVISORS, INC.	1.85%	4M	14.28M	1.35M	+50.66%
Sep 30, 2025	VESTAL POINT CAPITAL, LP	1.86%	4.02M	14.33M	-7M	-63.55%
Sep 30, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	3.68%	7.96M	28.43M	0	0
Sep 30, 2025	VANGUARD GROUP INC	3.84%	8.31M	29.68M	-140.79K	-1.67%
Sep 30, 2025	BLACKROCK, INC.	3.9%	8.45M	30.16M	-1.33M	-13.58%
Sep 30, 2025	NANTAHALA CAPITAL MANAGEMENT, LLC	4.05%	8.78M	31.33M	450K	+5.41%
Sep 30, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	5.3%	11.46M	40.92M	0	0
Sep 30, 2025	TCG CROSSOVER MANAGEMENT, LLC	5.71%	12.36M	44.13M	0	0
Sep 30, 2025	VR ADVISER, LLC	5.86%	12.68M	45.27M	3.8M	+42.74%
Sep 30, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	8.13%	17.6M	62.83M	0	0
Sep 30, 2025	NEA MANAGEMENT COMPANY, LLC	11.31%	24.47M	87.36M	0	0
Sep 30, 2025	FMR LLC	0%	7.2K	25.71K	1.55K	+27.45%
Sep 30, 2025	SIMPLEX TRADING, LLC	0%	10.3K	36K	-1.53K	-12.94%
Sep 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0%	10.48K	37.41K	9.46K	+930.48%
Sep 30, 2025	AMERITAS INVESTMENT PARTNERS, INC.	0.01%	11.69K	41.73K	0	0
Sep 30, 2025	LEGAL & GENERAL GROUP PLC	0.01%	12.1K	43.2K	-42.6K	-77.87%
Sep 30, 2025		0.01%	12.21K	43.58K	12.21K	+100.00%
Sep 30, 2025	CITIGROUP INC	0.01%	12.94K	46.21K	-40.23K	-75.66%
Sep 30, 2025	PRUDENTIAL FINANCIAL INC	0.01%	13.15K	46.93K	150	+1.15%
Sep 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.01%	13.86K	49.46K	0	0
Sep 30, 2025	CHOREO, LLC	0.01%	14.66K	52.33K	0	0
Sep 30, 2025	OPPENHEIMER & CO INC	0.01%	15.5K	55.34K	0	0
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.01%	25.15K	89.8K	11.68K	+86.70%
Sep 30, 2025	KOVITZ INVESTMENT GROUP PARTNERS, LLC	0.01%	25.21K	90.01K	0	0
Sep 30, 2025	PROSHARE ADVISORS LLC	0.01%	25.74K	91.88K	-6.66K	-20.56%
Sep 30, 2025	Y-INTERCEPT (HONG KONG) LTD	0.01%	26.8K	95.67K	26.8K	+100.00%
Sep 30, 2025	FARTHER FINANCE ADVISORS, LLC	0.01%	29.18K	104.16K	-8.83K	-23.22%
Sep 30, 2025	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.01%	30.3K	108.16K	-4.42K	-12.73%
Sep 30, 2025	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0.02%	33.93K	121.11K	7.7K	+29.37%
Sep 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.02%	46.3K	165.3K	-22.86K	-33.06%
Sep 30, 2025	SIVIA CAPITAL PARTNERS, LLC	0.02%	48.5K	173.15K	7K	+16.87%
Sep 30, 2025	QUADRATURE CAPITAL LTD	0.02%	52.04K	185.26K	33.58K	+181.92%
Sep 30, 2025	STONEPINE CAPITAL MANAGEMENT, LLC	0.03%	60K	214.2K	-25K	-29.41%
Sep 30, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.03%	60.31K	215.29K	-15.33K	-20.27%
Sep 30, 2025	JPMORGAN CHASE & CO	0.03%	63.84K	227.89K	-4.67K	-6.82%
Sep 30, 2025	ENTRYPOINT CAPITAL, LLC	0.04%	81.65K	291.48K	-96.85K	-54.26%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0.04%	84.09K	300.2K	6.2K	+7.96%
Sep 30, 2025	UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH	0.05%	110K	392.7K	0	0
Sep 30, 2025	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.06%	123.79K	441.93K	123.79K	+100.00%
Sep 30, 2025	RHUMBLINE ADVISERS	0.07%	157.57K	562.51K	-12.61K	-7.41%
Sep 30, 2025	TWO SIGMA INVESTMENTS, LP	0.07%	158.02K	564.12K	-124.75K	-44.12%
Sep 30, 2025	INVESCO LTD.	0.08%	171.27K	611.42K	50.38K	+41.67%
Sep 30, 2025	BARCLAYS PLC	0.08%	176.52K	630.16K	-77.31K	-30.46%
Sep 30, 2025	NUVEEN, LLC	0.11%	236.84K	845.5K	-83.44K	-26.05%
Sep 30, 2025	WOODLINE PARTNERS LP	0.11%	237.22K	846.88K	81.36K	+52.20%
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.12%	260.1K	928.56K	260.1K	+100.00%
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.13%	273.36K	975.88K	3.87K	+1.44%
Sep 30, 2025	D. E. SHAW & CO., INC.	0.17%	372.03K	1.33M	292.31K	+366.71%
Sep 30, 2025	GSA CAPITAL PARTNERS LLP	0.17%	372.45K	1.33M	-336.01K	-47.43%
Sep 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.19%	419.8K	1.5M	-106.36K	-20.21%
Sep 30, 2025	F/M INVESTMENTS LLC	0.2%	433.71K	1.55M	118.87K	+37.75%
Sep 30, 2025	SWEDBANK AB	0.25%	550K	1.96M	550K	+100.00%
Sep 30, 2025	JANE STREET GROUP, LLC	0.28%	605.57K	2.16M	605.57K	+100.00%
Sep 30, 2025	ROYAL BANK OF CANADA	0.3%	654.4K	2.34M	612.77K	+1,472.16%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	0.31%	662.25K	2.36M	132.17K	+24.93%
Sep 30, 2025	CITADEL ADVISORS LLC	0.31%	668.11K	2.39M	557.32K	+503.07%
Sep 30, 2025	UBS GROUP AG	0.32%	695.73K	2.48M	479.12K	+221.19%
Sep 30, 2025	DIMENSIONAL FUND ADVISORS LP	0.32%	700.65K	2.5M	55.17K	+8.55%
Sep 30, 2025	SIO CAPITAL MANAGEMENT, LLC	0.34%	726.85K	2.59M	0	0
Sep 30, 2025	MILLENNIUM MANAGEMENT LLC	0.39%	844.18K	3.01M	844.18K	+100.00%
Sep 30, 2025	DEUTSCHE BANK AG\	0.39%	850.98K	3.04M	19.93K	+2.40%
Sep 30, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.4%	856.6K	3.06M	59.48K	+7.46%
Sep 30, 2025	NORTHERN TRUST CORP	0.44%	946.73K	3.38M	-122.92K	-11.49%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.45%	963.8K	3.44M	-31.71K	-3.19%
Sep 30, 2025	AXA INVESTMENT MANAGERS S.A.	0.49%	1.05M	3.76M	1.05M	+100.00%
Sep 30, 2025	SUPERSTRING CAPITAL MANAGEMENT LP	0.6%	1.31M	4.67M	193.86K	+17.38%
Sep 30, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.62%	1.35M	4.82M	40.1K	+3.06%
Sep 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.69%	1.5M	5.36M	1M	+200.00%
Jun 30, 2025	NUVEEN, LLC	0.15%	320.27K	730.22K	-64.83K	-16.83%
Jun 30, 2025	SOFINNOVA INVESTMENTS, INC.	1.14%	2.46M	5.6M	-3.02M	-55.17%
Jun 30, 2025	EMERALD MUTUAL FUND ADVISERS TRUST	1.01%	2.19M	4.99M	171.95K	+8.54%
Jun 30, 2025		0.05%	110K	250.8K	-27.69K	-20.11%
Jun 30, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.37%	797.12K	1.82M	716.09K	+883.74%
Jun 30, 2025	SIO CAPITAL MANAGEMENT, LLC	0.34%	726.85K	1.66M	7.2K	+1.00%
Jun 30, 2025	GSA CAPITAL PARTNERS LLP	0.33%	708.46K	1.62M	620.76K	+707.78%
Jun 30, 2025	DIMENSIONAL FUND ADVISORS LP	0.3%	645.47K	1.47M	356.8K	+123.60%
Jun 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.24%	526.16K	1.2M	-271.17K	-34.01%
Jun 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.23%	500K	1.14M	500K	+100.00%
Jun 30, 2025	F/M INVESTMENTS LLC	0.15%	314.85K	717.85K	91.83K	+41.18%
Jun 30, 2025	RHUMBLINE ADVISERS	0.08%	170.18K	387.99K	16.63K	+10.83%
Jun 30, 2025	INVESCO LTD.	0.06%	120.89K	275.63K	31.63K	+35.44%
Jun 30, 2025	NEA MANAGEMENT COMPANY, LLC	11.31%	24.47M	55.79M	0	0
Jun 30, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	8.13%	17.6M	40.13M	0	0
Jun 30, 2025	TCG CROSSOVER MANAGEMENT, LLC	5.71%	12.36M	28.19M	0	0
Jun 30, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	5.3%	11.46M	26.13M	0	0
Jun 30, 2025	NANTAHALA CAPITAL MANAGEMENT, LLC	3.85%	8.33M	18.98M	250K	+3.10%
Jun 30, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	3.68%	7.96M	18.16M	0	0
Jun 30, 2025	FARALLON CAPITAL MANAGEMENT LLC	3.16%	6.84M	15.58M	0	0
Jun 30, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	1.66%	3.6M	8.21M	2.24M	+164.70%
Jun 30, 2025	QUARRY LP	0.01%	17K	38.76K	10K	+142.86%
Jun 30, 2025	CIBC WORLD MARKETS CORP	0.01%	15.59K	35.54K	-11.14K	-41.67%
Jun 30, 2025	CHOREO, LLC	0.01%	14.66K	33.42K	0	0
Jun 30, 2025	VR ADVISER, LLC	4.1%	8.88M	20.26M	5.63M	+172.72%
Jun 30, 2025	ROSALIND ADVISORS, INC.	1.23%	2.65M	6.05M	0	0
Jun 30, 2025	XTX TOPCO LTD	0.04%	88.1K	200.86K	88.1K	+100.00%
Jun 30, 2025	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0.04%	86.47K	197.14M	0	0
Jun 30, 2025	STONEPINE CAPITAL MANAGEMENT, LLC	0.04%	85K	193.8K	55.92K	+192.31%
Jun 30, 2025	ALGERT GLOBAL LLC	0.04%	79.95K	182K	-53.02K	-39.87%
Jun 30, 2025	D. E. SHAW & CO., INC.	0.04%	79.71K	181.75M	23.45K	+41.69%
Jun 30, 2025	SKOPOS LABS, INC.	0.04%	77.91K	177.64K	54.3K	+229.98%
Jun 30, 2025	MIRAE ASSET GLOBAL ETFS HOLDINGS LTD.	0.03%	69.85K	159.25K	-1.38K	-1.94%
Jun 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.03%	69.17K	157.7K	-8.52K	-10.97%
Jun 30, 2025	ROYAL BANK OF CANADA	0.02%	41.62K	95K	41.62K	+100.00%
Jun 30, 2025	VIRTUS INVESTMENT ADVISERS, INC.	0.02%	41.61K	94.86K	-7.4K	-15.10%
Jun 30, 2025	SIVIA CAPITAL PARTNERS, LLC	0.02%	41.5K	94.62K	3.46K	+9.09%
Jun 30, 2025	SUSQUEHANNA PORTFOLIO STRATEGIES, LLC	0.02%	39.84K	90.83K	39.84K	+100.00%
Jun 30, 2025	FARTHER FINANCE ADVISORS, LLC	0.02%	38K	86.64K	5.69K	+17.60%
Jun 30, 2025	LOS ANGELES CAPITAL MANAGEMENT LLC	0.01%	30.4K	69.3K	30.4K	+100.00%
Jun 30, 2025	KOVITZ INVESTMENT GROUP PARTNERS, LLC	0.01%	25.21K	57.49K	0	0
Jun 30, 2025	ARIZONA STATE RETIREMENT SYSTEM	0.01%	22.63K	51.59K	-4.45K	-16.43%
Jun 30, 2025	BROWN ADVISORY INC	0.01%	20.85K	47.55K	0	0
Jun 30, 2025	QUADRATURE CAPITAL LTD	0.01%	18.46K	41.99K	18.46K	+100.00%
Jun 30, 2025	VANGUARD GROUP INC	3.91%	8.45M	19.28M	334.73K	+4.12%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.24%	530.08K	1.21B	62.53K	+13.37%
Jun 30, 2025	MORGAN STANLEY	0.18%	382.61K	872.36M	127.1K	+49.74%
Jun 30, 2025	WOODLINE PARTNERS LP	0.07%	155.86K	355.36K	-96.05K	-38.13%
Jun 30, 2025	ALLIANCEBERNSTEIN L.P.	0.06%	137.09K	312.57M	36.32K	+36.04%
Jun 30, 2025	VESTAL POINT CAPITAL, LP	5.09%	11.02M	25.11M	15K	+0.14%
Jun 30, 2025	BLACKROCK, INC.	4.52%	9.78M	22.29M	-170.74K	-1.72%
Jun 30, 2025	EMERALD ADVISERS, LLC	1.63%	3.53M	8.06M	444.16K	+14.37%
Jun 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	1.55%	3.35M	7.64M	-812.38K	-19.52%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.37%	2.97M	6.77M	147.95K	+5.24%
Jun 30, 2025	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.14%	309.84K	706.42K	-469.12K	-60.22%
Jun 30, 2025	TWO SIGMA INVESTMENTS, LP	0.13%	282.76K	644.7K	-122.84K	-30.29%
Jun 30, 2025	BANK OF NEW YORK MELLON CORP	0.12%	269.49K	614.43K	6.55K	+2.49%
Jun 30, 2025	BARCLAYS PLC	0.12%	253.83K	579K	92.35K	+57.19%
Jun 30, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.1%	221.67K	505.41K	62.62K	+39.37%
Jun 30, 2025	UBS GROUP AG	0.1%	216.61K	493.87K	32.35K	+17.56%
Jun 30, 2025	TWO SIGMA ADVISERS, LP	0.09%	199.32K	454.44K	-64.4K	-24.42%
Jun 30, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	0.08%	182.3K	415.64K	182.3K	+100.00%
Jun 30, 2025	ENTRYPOINT CAPITAL, LLC	0.08%	178.5K	406.98K	-3.16K	-1.74%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.07%	160.08K	364.98K	10.45K	+6.98%
Jun 30, 2025	STATE STREET CORP	1.14%	2.46M	5.6M	7.29K	+0.30%
Jun 30, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.61%	1.31M	2.99M	26.08K	+2.03%
Jun 30, 2025	SUPERSTRING CAPITAL MANAGEMENT LP	0.52%	1.12M	2.54M	149.18K	+15.44%
Jun 30, 2025	NORTHERN TRUST CORP	0.49%	1.07M	2.44M	13.48K	+1.28%
Jun 30, 2025	AXA S.A.	0.49%	1.05M	2.39M	1.69K	+0.16%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.46%	995.51K	2.27M	40.68K	+4.26%
Jun 30, 2025	DEUTSCHE BANK AG\	0.38%	831.05K	1.89M	-84.97K	-9.28%
Jun 30, 2025	ZURCHER KANTONALBANK (ZURICH CANTONALBANK)	0.07%	149.43K	340.69K	89.08K	+147.63%
Jun 30, 2025	SWISS NATIONAL BANK	0.07%	148.4K	338.35K	-29.6K	-16.63%
Jun 30, 2025	SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC	0.06%	123.36K	281.26K	-90.36K	-42.28%
Jun 30, 2025	UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH	0.05%	110K	250.8K	-27.69K	-20.11%
Mar 31, 2025	ENTRYPOINT CAPITAL, LLC	0.08%	181.66K	503.18K	78.37K	+75.87%
Mar 31, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	5.78%	11.46M	31.75M	2.8M	+32.35%
Mar 31, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.07%	159.05K	440.57K	2.07K	+1.32%
Mar 31, 2025	PRELUDE CAPITAL MANAGEMENT, LLC	0.12%	256.59K	710.77K	41.97K	+19.55%
Mar 31, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.37%	797.33K	2.21M	96.34K	+13.74%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.44%	954.83K	2.64M	-8.99K	-0.93%
Mar 31, 2025	TCG CROSSOVER MANAGEMENT, LLC	5.72%	12.36M	34.24M	0	0
Mar 31, 2025	DEUTSCHE BANK AG\	0.42%	916.02K	2.54M	-11.58K	-1.25%
Mar 31, 2025	VR ADVISER, LLC	1.64%	3.26M	9.02M	3.26M	+100.00%
Mar 31, 2025	BLACKROCK, INC.	4.6%	9.95M	27.55M	358.21K	+3.74%
Mar 31, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	8.88%	17.6M	48.75M	3.04M	+20.84%
Mar 31, 2025	RHUMBLINE ADVISERS	0.07%	153.54K	425.3K	12.12K	+8.57%
Mar 31, 2025	MORGAN STANLEY	0.12%	255.51K	707.77K	-140.45K	-35.47%
Mar 31, 2025	TWO SIGMA ADVISERS, LP	0.12%	263.72K	730.49K	-127K	-32.50%
Mar 31, 2025	DIMENSIONAL FUND ADVISORS LP	0.13%	288.67K	799.63K	145.01K	+100.94%
Mar 31, 2025		0.18%	385.1K	1.07M	385.1K	+100.00%
Mar 31, 2025	EXOME ASSET MANAGEMENT LLC	0.39%	836.4K	2.32M	136.7K	+19.54%
Mar 31, 2025	SUPERSTRING CAPITAL MANAGEMENT LP	0.45%	966.2K	2.68M	457.87K	+90.07%
Mar 31, 2025	TWO SIGMA INVESTMENTS, LP	0.19%	405.6K	1.12M	-379.87K	-48.36%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.22%	467.55K	1.3M	-198.94K	-29.85%
Mar 31, 2025	STATE STREET CORP	1.13%	2.45M	6.79M	-1.72M	-41.31%
Mar 31, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	0.69%	1.36M	3.77M	371.82K	+37.62%
Mar 31, 2025	NANTAHALA CAPITAL MANAGEMENT, LLC	4.07%	8.08M	22.37M	550.12K	+7.31%
Mar 31, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	4.02%	7.96M	22.06M	0	0
Mar 31, 2025	VANGUARD GROUP INC	3.76%	8.12M	22.49M	-190.72K	-2.30%
Mar 31, 2025	VESTAL POINT CAPITAL, LP	5.55%	11M	30.47M	225K	+2.09%
Mar 31, 2025	NEA MANAGEMENT COMPANY, LLC	11.32%	24.47M	67.79M	0	0
Mar 31, 2025	BANK OF NEW YORK MELLON CORP	0.12%	262.94K	728.33K	9.31K	+3.67%
Mar 31, 2025	FARALLON CAPITAL MANAGEMENT LLC	3.16%	6.84M	18.93M	0	0
Mar 31, 2025	UBS GROUP AG	0.09%	184.26K	510.39K	49.33K	+36.56%
Mar 31, 2025	BARCLAYS PLC	0.07%	161.48K	448K	-75.22K	-31.78%
Mar 31, 2025	SIO CAPITAL MANAGEMENT, LLC	0.36%	719.65K	1.99M	715.91K	+19,106.14%
Mar 31, 2025	JPMORGAN CHASE & CO	1.01%	2.18M	6.05M	760.52K	+53.44%
Mar 31, 2025	EMERALD MUTUAL FUND ADVISERS TRUST	0.93%	2.01M	5.58M	638.57K	+46.41%
Mar 31, 2025	WALLEYE CAPITAL LLC	0.1%	207.3K	574.22K	207.3K	+100.00%
Mar 31, 2025	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.36%	778.95K	2.16M	-58.51K	-6.99%
Mar 31, 2025	READYSTATE ASSET MANAGEMENT LP	0.24%	522.79K	1.45M	-7.53K	-1.42%
Mar 31, 2025	CITADEL ADVISORS LLC	0.23%	504.01K	1.4M	330.62K	+190.67%
Mar 31, 2025	ROSALIND ADVISORS, INC.	1.23%	2.65M	7.35M	0	0
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.31%	2.82M	7.82M	38.2K	+1.37%
Mar 31, 2025	EMERALD ADVISERS, LLC	1.43%	3.09M	8.56M	757.53K	+32.47%
Mar 31, 2025	SWISS NATIONAL BANK	0.08%	178K	493.06K	0	0
Mar 31, 2025	SOFINNOVA INVESTMENTS, INC.	2.77%	5.48M	15.18M	10.37K	+0.19%
Mar 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	1.93%	4.16M	11.53M	-1.32M	-24.06%
Mar 31, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.59%	1.28M	3.56M	72.62K	+5.99%
Mar 31, 2025	NORTHERN TRUST CORP	0.49%	1.06M	2.93M	-21.19K	-1.97%
Mar 31, 2025	AXA S.A.	0.49%	1.05M	2.9M	-1.33K	-0.13%
Mar 31, 2025	WOODLINE PARTNERS LP	0.12%	251.91K	697.8K	-2.44M	-90.62%
Mar 31, 2025	F/M INVESTMENTS LLC	0.1%	223.02K	617.75K	141.67K	+174.17%
Mar 31, 2025	SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC	0.1%	213.71K	591.99K	-14.82K	-6.49%
Mar 31, 2024	TWO SIGMA ADVISERS, LP	0.28%	499.12K	2.49M	462.9K	+1,278.20%
Mar 31, 2024	TWO SIGMA INVESTMENTS, LP	0.31%	562.19K	2.8M	426.34K	+313.85%
Mar 31, 2024	NORTHERN TRUST CORP	0.45%	803.16K	4M	8.25K	+1.04%
Mar 31, 2024	WALLEYE CAPITAL LLC	0.56%	1.03M	5.11M	936.91K	+1,053.59%
Mar 31, 2024	PRUDENTIAL FINANCIAL INC	0.62%	1.14M	5.67M	164.9K	+16.95%
Mar 31, 2024	AFFINITY ASSET ADVISORS, LLC	0.63%	1.15M	5.73M	0	0
Mar 31, 2024	ALTIUM CAPITAL MANAGEMENT LP	0.73%	1.34M	6.65M	2K	+0.15%
Mar 31, 2024	GHOST TREE CAPITAL, LLC	0.88%	1.6M	7.97M	850K	+113.33%
Mar 31, 2024	NANTAHALA CAPITAL MANAGEMENT, LLC	0.95%	1.74M	8.65M	749.51K	+75.87%
Mar 31, 2024	STATE STREET CORP	1.05%	1.88M	9.36M	112.01K	+6.34%
Mar 31, 2024	SUPERSTRING CAPITAL MANAGEMENT LP	1.13%	2.07M	10.28M	1.25M	+153.62%
Mar 31, 2024	VIVO CAPITAL, LLC	1.14%	2.09M	10.4M	0	0
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	1.32%	2.37M	11.79M	40.93K	+1.76%
Mar 31, 2024	JANUS HENDERSON GROUP PLC	1.4%	2.56M	12.75M	746.41K	+41.07%
Mar 31, 2024	WELLINGTON MANAGEMENT GROUP LLP	1.55%	2.78M	13.84M	719.01K	+34.90%
Mar 31, 2024	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	2.19%	4M	19.92M	0	0
Mar 31, 2024	VANGUARD GROUP INC	3.37%	6.06M	30.2M	148.67K	+2.51%
Mar 31, 2024	ADAGE CAPITAL PARTNERS GP, L.L.C.	4.54%	8.29M	41.27M	650K	+8.51%
Mar 31, 2024	NEA MANAGEMENT COMPANY, LLC	13.41%	24.47M	121.87M	0	0
Mar 31, 2024	BLACKROCK INC.	4.03%	7.24M	36.06M	-19.72K	-0.27%
Mar 31, 2024	JENNISON ASSOCIATES LLC	4.84%	8.84M	44.03M	26.61K	+0.30%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.09%	162.21K	807.82K	0	0
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.05%	88.55K	440.97K	55.85K	+170.78%
Mar 31, 2024	FARALLON CAPITAL MANAGEMENT LLC	1.31%	2.39M	11.92M	-3.86M	-61.72%
Mar 31, 2024	DEUTSCHE BANK AG\	0.42%	753.89K	3.75M	720.72K	+2,173.13%
Mar 31, 2024	OPALEYE MANAGEMENT INC.	0.47%	855K	4.26M	855K	+100.00%
Mar 31, 2024	SOFINNOVA INVESTMENTS, INC.	1.29%	2.35M	11.69M	-35.57K	-1.49%
Mar 31, 2024	CITIGROUP INC	0.01%	17.32K	86.25K	2K	+13.07%
Mar 31, 2024	ARIZONA STATE RETIREMENT SYSTEM	0.01%	20.47K	101.94K	20.47K	+100.00%
Mar 31, 2024	BROWN ADVISORY INC	0.01%	20.85K	103.85K	0	0
Mar 31, 2024	STRS OHIO	0.01%	22.8K	113K	22.8K	+100.00%
Mar 31, 2024	KOVITZ INVESTMENT GROUP PARTNERS, LLC	0.01%	25.21K	125.57K	25.21K	+100.00%
Mar 31, 2024	PROSHARE ADVISORS LLC	0.01%	25.72K	128.06K	2.11K	+8.96%
Mar 31, 2024	FARTHER FINANCE ADVISORS, LLC	0.01%	25.78K	124.79K	0	0
Mar 31, 2024	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.01%	26.04K	130K	10.38K	+66.32%
Mar 31, 2024	HARVEST INVESTMENT SERVICES, LLC	0.02%	28.72K	143.05K	28.72K	+100.00%
Mar 31, 2024	NEW YORK STATE COMMON RETIREMENT FUND	0.02%	30.46K	152K	12.44K	+69.08%
Mar 31, 2024	BELVEDERE TRADING LLC	0.02%	33.6K	167.33K	33.6K	+100.00%
Mar 31, 2024	WELLS FARGO & COMPANY/MN	0.02%	33.67K	167.65K	3.57K	+11.85%
Mar 31, 2024	SG AMERICAS SECURITIES, LLC	0.02%	33.72K	168K	-16.15K	-32.38%
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	0.02%	34.1K	169.82K	11.59K	+51.49%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.02%	35.92K	178.86K	0	0
Mar 31, 2024	SIVIA CAPITAL PARTNERS, LLC	0.02%	37.5K	186.75K	1.5K	+4.17%
Mar 31, 2024	METLIFE INVESTMENT MANAGEMENT, LLC	0.02%	39.81K	198.26K	-8.81K	-18.11%
Mar 31, 2024	INVESCO LTD.	0.02%	43.21K	215.19K	-59.78K	-58.04%
Mar 31, 2024	AMERICAN INTERNATIONAL GROUP, INC.	0.02%	44.52K	221.71K	-383	-0.85%
Mar 31, 2024	STATE OF WISCONSIN INVESTMENT BOARD	0.03%	55K	273.91K	55K	+100.00%
Mar 31, 2024	JUMP FINANCIAL, LLC	0.04%	63.88K	318.1K	-72.82K	-53.27%
Mar 31, 2024	LEGAL & GENERAL GROUP PLC	0.04%	64.01K	318.79M	56.51K	+752.50%
Mar 31, 2024	NEW YORK LIFE INVESTMENT MANAGEMENT LLC	0.04%	72.62K	361.67K	72.62K	+100.00%
Mar 31, 2024	BNP PARIBAS ARBITRAGE, SNC	0.04%	73.49K	366K	35.27K	+92.27%
Mar 31, 2024	SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC	0.04%	79.07K	393.78K	79.07K	+100.00%
Mar 31, 2024	CREDIT SUISSE AG/	0.05%	90.71K	451.71K	90.71K	+100.00%
Mar 31, 2024	ALPS ADVISORS INC	0.05%	95.46K	475.4K	4.54K	+5.00%
Mar 31, 2024	AWM INVESTMENT COMPANY, INC.	0.05%	100K	498K	100K	+100.00%
Mar 31, 2024	UBS GROUP AG	0.06%	108.69K	541.26K	2.45K	+2.31%
Mar 31, 2024	OPTIONS SOLUTIONS, LLC	0.06%	110.67K	551.13K	110.67K	+100.00%
Mar 31, 2024	QUBE RESEARCH & TECHNOLOGIES LTD	0.07%	120.94K	602.29K	-4.81K	-3.82%
Mar 31, 2024	RHUMBLINE ADVISERS	0.07%	133.93K	666.96K	3.87K	+2.97%
Mar 31, 2024	DIMENSIONAL FUND ADVISORS LP	0.08%	138.21K	688.29K	-7.06K	-4.86%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.08%	144.88K	721.5K	17.68K	+13.90%
Mar 31, 2024	SWISS NATIONAL BANK	0.08%	147K	732.06K	147K	+100.00%
Mar 31, 2024	JPMORGAN CHASE & CO	0.09%	166.99K	831.62K	80.65K	+93.41%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.09%	169.23K	842.74K	89.02K	+111.00%
Mar 31, 2024	SCHONFELD STRATEGIC ADVISORS LLC	0.1%	177.1K	881.96K	156.5K	+759.71%
Mar 31, 2024	ALGERT GLOBAL LLC	0.11%	197.43K	983K	197.43K	+100.00%
Mar 31, 2024	MORGAN STANLEY	0.13%	231.56K	1.15M	10.05K	+4.54%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.13%	242.58K	1.21M	-5.99K	-2.41%
Mar 31, 2024	CLARIVEST ASSET MANAGEMENT LLC	0.14%	249.31K	1.24M	467	+0.19%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.14%	256.18K	1.28M	-39.52K	-13.36%
Mar 31, 2024	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.22%	392.72K	1.96M	124.28K	+46.29%
Mar 31, 2024	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.59%	1.09M	5.41M	1.09M	+100.00%
Mar 31, 2024	AXA S.A.	0.73%	1.33M	6.63M	-417.24K	-23.87%
Mar 31, 2024	TCG CROSSOVER MANAGEMENT, LLC	5.48%	10M	49.8M	0	0
Mar 31, 2024	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	7.98%	14.57M	72.54M	332.71K	+2.34%
Dec 31, 2023	VR ADVISER, LLC	2.13%	3.5M	16.45M	-3.68M	-51.29%
Dec 31, 2023	SOFINNOVA INVESTMENTS, INC.	1.45%	2.38M	11.2M	2.22M	+1,409.00%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.42%	2.33M	10.94M	105.39K	+4.74%
Dec 31, 2023	RENAISSANCE TECHNOLOGIES LLC	0.16%	256.9K	1.21M	153K	+147.26%
Dec 31, 2023	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.16%	268.45K	1.26M	42.22K	+18.66%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.18%	295.7K	1.39M	34.27K	+13.11%
Dec 31, 2023	CAXTON CORP	0.22%	353.44K	1.66M	-2.96M	-89.33%
Dec 31, 2023	VIVO CAPITAL, LLC	1.27%	2.09M	9.82M	174.97K	+9.14%
Dec 31, 2023	BLACKROCK INC.	4.42%	7.26M	34.13M	1.22M	+20.23%
Dec 31, 2023	ADAGE CAPITAL PARTNERS GP, L.L.C.	4.65%	7.64M	35.9M	-300.62K	-3.79%
Dec 31, 2023	JENNISON ASSOCIATES LLC	5.36%	8.82M	41.43M	4.95M	+127.98%
Dec 31, 2023	TCG CROSSOVER MANAGEMENT, LLC	6.08%	10M	47M	0	0
Dec 31, 2023	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	8.66%	14.23M	66.89M	0	0
Dec 31, 2023	NEA MANAGEMENT COMPANY, LLC	14.89%	24.47M	115.01M	0	0
Dec 31, 2023	SG AMERICAS SECURITIES, LLC	0.03%	49.86K	234K	12.72K	+34.25%
Dec 31, 2023	JANE STREET GROUP, LLC	0.04%	60.46K	284.15K	60.46K	+100.00%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.05%	80.2K	376.94K	-17.37K	-17.80%
Dec 31, 2023	JPMORGAN CHASE & CO	0.05%	86.34K	405.81K	24.76K	+40.20%
Dec 31, 2023	WALLEYE CAPITAL LLC	0.05%	88.93K	417.95K	88.93K	+100.00%
Dec 31, 2023	ALPS ADVISORS INC	0.06%	90.92K	427.32K	90.92K	+100.00%
Dec 31, 2023	INVESCO LTD.	0.06%	102.99K	484.05K	32.48K	+46.06%
Dec 31, 2023	UBS GROUP AG	0.06%	106.24K	499.31K	51.77K	+95.03%
Dec 31, 2023	BARCLAYS PLC	0.08%	123.96K	582K	107.93K	+673.37%
Dec 31, 2023	QUBE RESEARCH & TECHNOLOGIES LTD	0.08%	125.75K	591.02K	125.75K	+100.00%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.08%	127.2K	597.84K	38.9K	+44.05%
Dec 31, 2023	RHUMBLINE ADVISERS	0.08%	130.06K	611.29K	8.53K	+7.02%
Dec 31, 2023	TWO SIGMA INVESTMENTS, LP	0.08%	135.84K	638.46K	135.84K	+100.00%
Dec 31, 2023	JUMP FINANCIAL, LLC	0.08%	136.7K	642.49K	104.17K	+320.28%
Dec 31, 2023	DIMENSIONAL FUND ADVISORS LP	0.09%	145.28K	682.79K	-18.87K	-11.50%
Dec 31, 2023	NUVEEN ASSET MANAGEMENT, LLC	0.1%	162.21K	762.4K	0	0
Dec 31, 2023	CITADEL ADVISORS LLC	0.1%	169.94K	798.72K	150.36K	+767.70%
Dec 31, 2023	UBS OCONNOR LLC	0.11%	176.89K	831.36K	-203.47K	-53.49%
Dec 31, 2023	WELLINGTON MANAGEMENT GROUP LLP	1.25%	2.06M	9.68M	2.06M	+100.00%
Dec 31, 2023	JANUS HENDERSON GROUP PLC	1.11%	1.82M	8.55M	-183.29K	-9.16%
Dec 31, 2023	STATE STREET CORP	1.08%	1.77M	8.31M	230.74K	+15.01%
Dec 31, 2023	AXA S.A.	1.06%	1.75M	8.21M	-42.28K	-2.36%
Dec 31, 2023	ALTIUM CAPITAL MANAGEMENT LP	0.81%	1.33M	6.27M	1.33M	+100.00%
Dec 31, 2023	AFFINITY ASSET ADVISORS, LLC	0.7%	1.15M	5.41M	0	0
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	0.63%	1.04M	4.9M	1.04M	+100.00%
Dec 31, 2023	NANTAHALA CAPITAL MANAGEMENT, LLC	0.6%	987.9K	4.64M	-51.46K	-4.95%
Dec 31, 2023	PRUDENTIAL FINANCIAL INC	0.59%	972.95K	4.57M	593.01K	+156.08%
Dec 31, 2023		0.5%	814.27K	3.83M	814.27K	+100.00%
Dec 31, 2023	NORTHERN TRUST CORP	0.48%	794.91K	3.74M	47.92K	+6.41%
Dec 31, 2023	MORGAN STANLEY	0.13%	221.51K	1.04M	145.58K	+191.74%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.15%	248.56K	1.17M	0	0
Dec 31, 2023	CLARIVEST ASSET MANAGEMENT LLC	0.15%	248.84K	1.17M	5.94K	+2.45%
Dec 31, 2023	GHOST TREE CAPITAL, LLC	0.46%	750K	3.53M	750K	+100.00%
Dec 31, 2023	FARALLON CAPITAL MANAGEMENT LLC	3.81%	6.26M	29.4M	-4.65M	-42.65%
Dec 31, 2023	VANGUARD GROUP INC	3.6%	5.91M	27.8M	150.35K	+2.61%
Dec 31, 2023	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	2.43%	4M	18.8M	0	0

Insiders

Insiders	Designation	Shares Held
YANG RICK	10 percent owner	24.47M
WALKER PAUL EDWARD	10 percent owner	24.47M
BEHBAHANI ALI	10 percent owner	24.47M
SANDELL SCOTT D	10 percent owner	24.47M
MATHERS EDWARD T	10 percent owner	24.47M
CHANG CARMEN	10 percent owner	24.47M
MAKHZOUMI MOHAMAD	10 percent owner	24.47M
FLORENCE ANTHONY A. JR.	10 percent owner	24.47M
BASKETT FOREST	10 percent owner	24.47M
GROWTH EQUITY OPPORTUNITIES 17, LLC	10 percent owner	24.47M
RAMSAY DAVID A	director	2.53M
PAULS MATTHEW	CHIEF EXECUTIVE OFFICER	1.54M
LOWRANCE DAVID L	Chief Financial Officer	381.01K
MCCRACKEN JOSEPH S	director	260.84K
CHOWDHURY BADRUL A.	CHIEF MEDICAL OFFICER	175K
PRATT RAYMOND DENNIS	Chief Medical Officer	160K
HAWKINS RICHARD J	director	115.47K
ELAM NEVAN C	director	22.5K

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Dec 19, 2025	RAMSAY DAVID A	SALE	6.06	20K	121.22K	2.53M
Jun 20, 2025	HAWKINS RICHARD J	PURCHASE	2.04	48.23K	98.57K	115.47K
May 29, 2025	MCCRACKEN JOSEPH S	PURCHASE	2.08	10K	20.83K	260.84K
Mar 31, 2025	RAMSAY DAVID A	PURCHASE	2.77	150K	416.25K	2.51M
Dec 16, 2024	HAWKINS RICHARD J	SALE	3.32	8K	26.57K	67.24K
Dec 16, 2024	PAULS MATTHEW	SALE	3.31	54.7K	180.83K	1.54M
Dec 16, 2024	LOWRANCE DAVID L	SALE	3.33	25K	83.28K	381.01K
Nov 19, 2024	MCCRACKEN JOSEPH S	PURCHASE	2.95	20K	59.07K	210.84K
Nov 18, 2024	RAMSAY DAVID A	PURCHASE	2.88	100K	287.6K	2.32M
Dec 28, 2023	PAULS MATTHEW	SALE	4.71	84K	395.9K	1.3M
Dec 28, 2023	ELAM NEVAN C	SALE	4.71	93.84K	442.29K	22.5K
Dec 28, 2023	LOWRANCE DAVID L	SALE	4.71	10K	47.13K	342.36K
Jul 17, 2023	WALKER PAUL EDWARD	PURCHASE	3.00	333.33K	1M	24.47M
Jul 17, 2023	BEHBAHANI ALI	PURCHASE	3.00	333.33K	1M	24.47M
Jul 17, 2023	YANG RICK	PURCHASE	3.00	333.33K	1M	24.47M
Jul 17, 2023	FLORENCE ANTHONY A. JR.	PURCHASE	3.00	333.33K	1M	24.47M
Jul 17, 2023	MAKHZOUMI MOHAMAD	PURCHASE	3.00	333.33K	1M	24.47M
Jul 17, 2023	SANDELL SCOTT D	PURCHASE	3.00	333.33K	1M	24.47M
Jul 17, 2023	GROWTH EQUITY OPPORTUNITIES 17, LLC	PURCHASE	3.00	333.33K	1M	24.47M
Jul 17, 2023	BASKETT FOREST	PURCHASE	3.00	333.33K	1M	24.47M
Jul 17, 2023	MATHERS EDWARD T	PURCHASE	3.00	333.33K	1M	24.47M
Jul 17, 2023	CHANG CARMEN	PURCHASE	3.00	333.33K	1M	24.47M
Jun 26, 2023	PRATT RAYMOND DENNIS	PURCHASE	2.93	6.5K	19.05K	160K
May 26, 2023	RAMSAY DAVID A	PURCHASE	2.63	37.12K	97.6K	2.2M
May 25, 2023	RAMSAY DAVID A	PURCHASE	2.57	12.88K	33.13K	2.16M
May 24, 2023	RAMSAY DAVID A	PURCHASE	2.56	50K	127.8K	2.15M
Dec 30, 2022	RAMSAY DAVID A	PURCHASE	1.55	29K	44.83K	2.1M
Dec 29, 2022	RAMSAY DAVID A	PURCHASE	1.54	7K	10.75K	2.07M
Dec 28, 2022	RAMSAY DAVID A	PURCHASE	1.50	3.29K	4.92K	2.07M
Dec 23, 2022	RAMSAY DAVID A	PURCHASE	1.44	15.71K	22.67K	2.06M
Dec 22, 2022	PRATT RAYMOND DENNIS	PURCHASE	1.54	3.5K	5.4K	153.5K
Dec 22, 2022	RAMSAY DAVID A	PURCHASE	1.48	41.41K	61.13K	2.05M
Dec 20, 2022	RAMSAY DAVID A	PURCHASE	1.50	13.83K	20.76K	2M
Dec 19, 2022	RAMSAY DAVID A	PURCHASE	1.49	40.72K	60.83K	1.99M
Dec 16, 2022	RAMSAY DAVID A	PURCHASE	1.50	341	511.5	1.95M
Nov 23, 2022	RAMSAY DAVID A	PURCHASE	1.44	4.61K	6.63K	1.95M
Nov 22, 2022	RAMSAY DAVID A	PURCHASE	1.42	15.5K	22.02K	1.94M
Nov 21, 2022	RAMSAY DAVID A	PURCHASE	1.42	25.01K	35.53K	1.93M
Nov 18, 2022	RAMSAY DAVID A	PURCHASE	1.34	16.1K	21.61K	1.9M
Nov 17, 2022	RAMSAY DAVID A	PURCHASE	1.27	8.9K	11.3K	1.89M
Sep 27, 2022	RAMSAY DAVID A	PURCHASE	1.37	73.89K	101.38K	1.88M
Sep 26, 2022	RAMSAY DAVID A	PURCHASE	1.38	31.11K	43.05K	1.8M
Sep 23, 2022	RAMSAY DAVID A	PURCHASE	1.42	30K	42.66K	1.77M
Sep 20, 2022	RAMSAY DAVID A	PURCHASE	1.45	600	870	1.74M
Sep 19, 2022	RAMSAY DAVID A	PURCHASE	1.46	1.4K	2.04K	1.74M
Sep 16, 2022	RAMSAY DAVID A	PURCHASE	1.44	6K	8.65K	1.74M
Sep 08, 2022	RAMSAY DAVID A	PURCHASE	1.40	29K	40.57K	1.73M
Sep 07, 2022	RAMSAY DAVID A	PURCHASE	1.39	2.13K	2.95K	1.7M
Sep 06, 2022	RAMSAY DAVID A	PURCHASE	1.38	870	1.2K	1.7M
Sep 01, 2022	RAMSAY DAVID A	PURCHASE	1.42	39.77K	56.47K	1.7M
Aug 31, 2022	RAMSAY DAVID A	PURCHASE	1.42	39.49K	56.2K	1.66M
Aug 30, 2022	RAMSAY DAVID A	PURCHASE	1.41	20.74K	29.26K	1.62M
Jun 21, 2022	RAMSAY DAVID A	PURCHASE	1.38	21.09K	29.11K	1.56M
Jun 17, 2022	RAMSAY DAVID A	PURCHASE	1.33	39.91K	52.92K	1.54M
Dec 30, 2021	RAMSAY DAVID A	PURCHASE	1.30	35K	45.36K	1.5M
Dec 29, 2021	RAMSAY DAVID A	PURCHASE	1.25	15K	18.68K	1.47M
Dec 17, 2021	RAMSAY DAVID A	PURCHASE	1.13	25K	28.23K	1.45M
Dec 17, 2021	LOWRANCE DAVID L	PURCHASE	1.14	4K	4.57K	142.79K
Dec 15, 2021	RAMSAY DAVID A	PURCHASE	1.08	15K	16.26K	1.43M
Dec 10, 2021	RAMSAY DAVID A	PURCHASE	1.04	35K	36.37K	1.41M
Dec 09, 2021	CHOWDHURY BADRUL A.	PURCHASE	1.05	25K	26.25K	175K
Dec 08, 2021	PAULS MATTHEW	PURCHASE	1.06	6.5K	6.89K	383.67K
Dec 08, 2021	RAMSAY DAVID A	PURCHASE	1.05	13.16K	13.81K	1.38M
Dec 07, 2021	RAMSAY DAVID A	PURCHASE	1.05	11.84K	12.4K	1.36M
Dec 02, 2021	PAULS MATTHEW	PURCHASE	1.10	10K	10.95K	377.17K
Dec 02, 2021	RAMSAY DAVID A	PURCHASE	1.09	21.39K	23.23K	1.35M
Dec 01, 2021	RAMSAY DAVID A	PURCHASE	1.08	9K	9.77K	1.33M
Nov 30, 2021	RAMSAY DAVID A	PURCHASE	1.09	16K	17.39K	1.32M
Nov 22, 2021	RAMSAY DAVID A	PURCHASE	1.08	90K	97.02K	1.3M
Nov 19, 2021	PAULS MATTHEW	PURCHASE	1.11	10K	11.1K	365.02K
Nov 19, 2021	RAMSAY DAVID A	PURCHASE	1.07	49.8K	53.24K	1.21M
Nov 18, 2021	RAMSAY DAVID A	PURCHASE	1.08	60.2K	65.14K	1.16M
Nov 18, 2021	PAULS MATTHEW	PURCHASE	1.10	10K	11K	355.02K
Sep 30, 2021	RAMSAY DAVID A	PURCHASE	1.30	50K	64.9K	1.1M
Sep 29, 2021	RAMSAY DAVID A	PURCHASE	1.28	47.5K	60.66K	1.05M
Sep 28, 2021	RAMSAY DAVID A	PURCHASE	1.28	39.55K	50.82K	1M
Aug 18, 2021	PAULS MATTHEW	PURCHASE	1.19	11.9K	14.17K	345.02K
Aug 18, 2021	RAMSAY DAVID A	PURCHASE	1.18	12.95K	15.28K	946.3K
Aug 17, 2021	RAMSAY DAVID A	PURCHASE	1.18	66.55K	78.2K	933.35K
Aug 17, 2021	PAULS MATTHEW	PURCHASE	1.18	15K	17.7K	333.12K
May 21, 2021	PAULS MATTHEW	PURCHASE	1.63	10K	16.3K	318.12K
May 19, 2021	RAMSAY DAVID A	PURCHASE	1.58	5K	7.9K	866.8K
May 18, 2021	RAMSAY DAVID A	PURCHASE	1.62	50K	81.1K	861.8K
May 17, 2021	CHOWDHURY BADRUL A.	SALE	1.56	50K	77.87K	150K
Apr 19, 2021	PAULS MATTHEW	PURCHASE	1.82	27.4K	49.87K	308.12K
Mar 22, 2021	PAULS MATTHEW	PURCHASE	2.07	24.1K	49.94K	280.72K
Mar 15, 2021	MCCRACKEN JOSEPH S	PURCHASE	1.45	68.97K	100K	168.34K
Mar 15, 2021	RAMSAY DAVID A	PURCHASE	1.45	689.66K	1M	811.8K
Mar 15, 2021	LOWRANCE DAVID L	PURCHASE	1.45	13.79K	20K	13.79K
Feb 22, 2021	PAULS MATTHEW	PURCHASE	1.74	28.7K	50.04K	256.62K
Jun 28, 2019	RAMSAY DAVID A	PURCHASE	2.33	18K	41.94K	104.99K
Jun 27, 2019	RAMSAY DAVID A	PURCHASE	2.45	5K	12.25K	69.69K
Jun 26, 2019	RAMSAY DAVID A	PURCHASE	2.38	900	2.14K	64.69K
Jun 18, 2019	RAMSAY DAVID A	PURCHASE	2.36	5K	11.8K	53.57K
Jun 17, 2019	RAMSAY DAVID A	PURCHASE	2.38	10K	23.8K	43.57K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES20K1

NET SHARES-20K1

SHARES HELD2.53M1

% NET SHARES-100.79%0%

SVRA Stock Ownership Breakdown

Savara

Stock Outstanding Shares

Market Insider

Institutional Ownership

Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions

Stock Outstanding Shares

Market Insider

Institutional Ownership

Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions