How many institutions own SLDB stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own SLDB shares is 176, representing 105.48% of the company's common stock.

Who are the major shareholders selling Solid Biosciences Inc. stock?

JPMORGAN CHASE & CO, in the last quarter, reduced its stake in SLDB by -11.05% restricting it's holding to 31.76 thousand shares of worth nearly $179.11K. BRIDGEWAY CAPITAL MANAGEMENT, LLC also lessened -39% of the SLDB shares from its portfolio, reducing its holding to 23.46 thousand shares of worth $132.31K. MANUFACTURERS LIFE INSURANCE COMPANY, THE also shunned SLDB shares holding by -18.84% last quarter which brought its holding to 18.25 thousand shares worth $102.95K.

Investors who are buying SLDB stock?

As per its latest 13F filing, BNP PARIBAS ARBITRAGE, SNC increased its stake in SLDB by 2.19% in the last quarter. The institutional holder raised its holding to 74.63 thousand shares having worth more than $420.91K. FOX RUN MANAGEMENT, L.L.C. also added 35.06% more shares of SLDB to its portfolio, raising its holding to 25.01 thousand shares of worth $141.03K. SG AMERICAS SECURITIES, LLC also increased its SLDB shares holding by 100% which brought its holding to 20.88 thousand shares worth $118.00K.

SLDB's major insiders: who are they?

The insider with the most stakes in SLDB is PERCEPTIVE ADVISORS LLC , at the company. Additionally, SLDB stock is highly held by 10 percent owner Bain Capital Life Sciences Investors, LLC and 10 percent owner Adage Capital Management, L.P. among others.

Did an insider recently sell SLDB stock?

Company executives, directors, and other insiders own 0.56% percent of Solid Biosciences Inc.'s stock. Within the last six months, there have been 29 transaction(s) in which SLDB insiders have sold stock, totaling 427.62K shares. Insiders that have sold shares include HERZICH PAUL, TAN KEVIN, and BROOKS GABRIEL.

Which insider recently purchased SLDB stock?

There have been 0 transaction(s) during the past 6-months in which Solid Biosciences Inc. insiders have bought stock, totalling 0 shares

How much of SLDB does insiders own?

Around 2.5M Solid Biosciences Inc. shares are held by insiders, which represents about 0.56% of SLDB stock.

Who is the insider with the largest stake?

SLDB , PERCEPTIVE ADVISORS LLC holds the largest portfolio of the company's shares. SLDB shares owned by PERCEPTIVE total nearly 11.83 million.

Which institution holds the most shares in SLDB?

BNP PARIBAS ARBITRAGE, SNC is the largest institutional owner in SLDB which holds 74.63 thousand shares worth $420.91K or 0.08% of the total SLDB shares outstanding followed by JPMORGAN CHASE & CO with ownership of 31.76 thousand shares representing 0.03% of the SLDB ownership. CIBC PRIVATE WEALTH GROUP, LLC is the third largest stakeholder with 30.6 thousand shares or 0.03% of the ownership worth more than $172.58K.

Is Solid Biosciences Inc. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the SLDB is concerned, it is a stock which is optionable.

Is there a short position on SLDB's shares?

Number of SLDB shares short is 9.78M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding SLDB shares are there?

As of today, 77.87M shares of SLDB are outstanding.

Is there many float in SLDB stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, SLDB has 37.61M shares in float.

SLDB short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for SLDB is 6.72.

Solid Biosciences (SLDB) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares12.56

Short Percent Of Float14.93

Shares Outstanding77.87M

Shares Float37.61M

Shares Short9.78M

Short Ratio6.72

14.93%

Short % of Float

12.56%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

0.56% Percentage of Shares held by All Insiders

105.48% Percentage of Shares held by All Institutions

106.07% Percentage of Float held by Institutions

176

Number of Institutions Holding Shares

Institutional Ownership

About 105.48% of SLDB shares are held by financial institutions. BNP PARIBAS ARBITRAGE, SNC is the top corporate investor, holding 74.63K shares valued at $420.91K. A 0.08% stake in Solid Biosciences Inc. is owned by the company. JPMORGAN CHASE & CO owns 31.76K shares valued at $179.11K, which translates its holding of 0.03% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Dec 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.08%	74.63K	420.91K	1.6K	+2.19%
Dec 31, 2025	JPMORGAN CHASE & CO	0.03%	31.76K	179.11K	-3.95K	-11.05%
Dec 31, 2025	CIBC PRIVATE WEALTH GROUP, LLC	0.03%	30.6K	172.58K	0	0
Dec 31, 2025	FOX RUN MANAGEMENT, L.L.C.	0.03%	25.01K	141.03K	6.49K	+35.06%
Dec 31, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.02%	23.46K	132.31K	-15K	-39.00%
Dec 31, 2025	SG AMERICAS SECURITIES, LLC	0.02%	20.88K	118K	20.88K	+100.00%
Dec 31, 2025	SIREN, L.L.C.	8.15%	7.69M	43.37M	274.5K	+3.70%
Dec 31, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.02%	18.25K	102.95K	-4.24K	-18.84%
Dec 31, 2025	LIDO ADVISORS, LLC	0.02%	20.18K	124.48K	0	0
Dec 31, 2025	AXQ CAPITAL, LP	0.02%	20.65K	116.45K	-3.39K	-14.10%
Dec 31, 2025	PERCEPTIVE ADVISORS LLC	12.53%	11.83M	66.74M	0	0
Dec 31, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	8.38%	7.91M	44.62M	0	0
Dec 31, 2025	RA CAPITAL MANAGEMENT, L.P.	6.16%	5.81M	32.78M	0	0
Dec 31, 2025	FMR LLC	2.15%	2.03M	11.45M	-884.23K	-30.34%
Dec 31, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	1.48%	1.4M	7.9M	-2.6M	-65.00%
Dec 31, 2025	FISHER ASSET MANAGEMENT, LLC	0.11%	103.48K	583.63K	103.48K	+100.00%
Dec 31, 2025	MILLENNIUM MANAGEMENT LLC	0.12%	116.63K	657.8K	-793.07K	-87.18%
Dec 31, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.04%	34.49K	194.5K	4.54K	+15.16%
Dec 31, 2025	XTX TOPCO LTD	0.04%	35.63K	200.97K	35.63K	+100.00%
Dec 31, 2025	FINEPOINT CAPITAL LP	1.02%	961.25K	5.42M	0	0
Dec 31, 2025	VESTAL POINT CAPITAL, LP	6.16%	5.82M	32.8M	2.84M	+95.46%
Dec 31, 2025	POINT72 ASSET MANAGEMENT, L.P.	2.56%	2.42M	13.63M	1.08M	+81.25%
Dec 31, 2025	REDMILE GROUP, LLC	1.97%	1.86M	10.49M	-38.8K	-2.04%
Dec 31, 2025	ALLY BRIDGE GROUP (NY) LLC	0.44%	413.63K	2.33M	-135.56K	-24.68%
Dec 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.2%	185.68K	1.05M	-40.72K	-17.98%
Dec 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.17%	161.54K	911.07K	-522	-0.32%
Dec 31, 2025	AQR CAPITAL MANAGEMENT LLC	0.14%	131.96K	744.24K	900	+0.69%
Dec 31, 2025	KNOTT DAVID M JR	0.17%	162.44K	916.16K	0	0
Dec 31, 2025	JANE STREET GROUP, LLC	0.23%	213.41K	1.2M	121.82K	+133.01%
Dec 31, 2025	PANAGORA ASSET MANAGEMENT INC	0.24%	226.76K	1.28M	-170.43K	-42.91%
Dec 31, 2025	BOXER CAPITAL MANAGEMENT, LLC	0.32%	300K	1.69M	-300K	-50.00%
Dec 31, 2025	BANK OF AMERICA CORP /DE/	0.36%	344.29K	1.94M	-445.7K	-56.42%
Dec 31, 2025	PARKMAN HEALTHCARE PARTNERS LLC	0.44%	418.37K	2.36M	21.98K	+5.54%
Dec 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.53%	499.29K	2.82M	-4.37K	-0.87%
Dec 31, 2025	ARMISTICE CAPITAL, LLC	2.77%	2.61M	14.73M	1.68M	+179.06%
Dec 31, 2025	Y-INTERCEPT (HONG KONG) LTD	0.04%	36.15K	203.87K	36.15K	+100.00%
Dec 31, 2025	DEUTSCHE BANK AG\	0.04%	39.96K	225.39K	-12.2K	-23.39%
Dec 31, 2025	CITADEL ADVISORS LLC	2.82%	2.66M	15.02M	71.17K	+2.74%
Dec 31, 2025	INVESCO LTD.	0.16%	152.13K	857.99K	34.76K	+29.61%
Dec 31, 2025	IKARIAN CAPITAL, LLC	0.17%	160.41K	904.71K	-16.28K	-9.21%
Dec 31, 2025	SCHONFELD STRATEGIC ADVISORS LLC	0.19%	182.87K	1.03M	114.87K	+168.92%
Dec 31, 2025	APIS CAPITAL ADVISORS, LLC	0.21%	196K	1.11M	0	0
Dec 31, 2025	SQUAREPOINT OPS LLC	0.05%	50.05K	282.31K	50.05K	+100.00%
Dec 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0.06%	52.8K	297.79K	-410.9K	-88.61%
Dec 31, 2025	SUSQUEHANNA PORTFOLIO STRATEGIES, LLC	0.21%	199.44K	1.12M	0	0
Dec 31, 2025	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0.02%	17.39K	98.07K	0	0
Dec 31, 2025	HRT FINANCIAL LP	0.02%	14.92K	84K	-141.9K	-90.49%
Dec 31, 2025	PROSHARE ADVISORS LLC	0.02%	14.22K	80.19K	1.36K	+10.59%
Dec 31, 2025	SEI INVESTMENTS CO	0.01%	13.08K	73.76K	0	0
Dec 31, 2025	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.01%	12.7K	71.6K	-954	-6.99%
Dec 31, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.01%	11.16K	62.94K	0	0
Dec 31, 2025	COMMONWEALTH EQUITY SERVICES, LLC	0.01%	10.85K	61.21K	0	0
Dec 31, 2025	BARCLAYS PLC	0.15%	138.14K	779.09K	-20.97K	-13.18%
Dec 31, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.15%	142.6K	804.26K	-44K	-23.58%
Dec 31, 2025	BANK OF NEW YORK MELLON CORP	0.15%	144.7K	816.1K	-3.96K	-2.66%
Dec 31, 2025	TWO SIGMA INVESTMENTS, LP	0.16%	153.41K	865.22K	-2.44K	-1.57%
Dec 31, 2025	MORGAN STANLEY	0.42%	394.27K	2.22M	136.42K	+52.91%
Dec 31, 2025	NUVEEN, LLC	0.42%	394.98K	2.23M	0	0
Dec 31, 2025	DIMENSIONAL FUND ADVISORS LP	0.72%	679.08K	3.83M	235.54K	+53.11%
Dec 31, 2025	SIMPLEX TRADING, LLC	0.06%	60.53K	341.41K	-23.47K	-27.94%
Dec 31, 2025	WOODLINE PARTNERS LP	0.34%	316.82K	1.79M	-315K	-49.86%
Dec 31, 2025	BIRCHVIEW CAPITAL, LP	0.75%	705.96K	3.98M	409K	+137.73%
Dec 31, 2025	UBS GROUP AG	0.97%	911.41K	5.14M	187.26K	+25.86%
Dec 31, 2025	GOLDMAN SACHS GROUP INC	1.07%	1.01M	5.68M	329.68K	+48.72%
Dec 31, 2025	STEWARD PARTNERS INVESTMENT ADVISORY, LLC	0.01%	4.96K	27.95K	0	0
Dec 31, 2025	BALYASNY ASSET MANAGEMENT L.P.	0.38%	360.94K	2.04M	-371.67K	-50.73%
Dec 31, 2025	NORTHERN TRUST CORP	0.44%	412.78K	2.33M	-33.74K	-7.56%
Dec 31, 2025	WELLS FARGO & COMPANY/MN	0.08%	76.11K	429.24K	30.9K	+68.35%
Dec 31, 2025	RHUMBLINE ADVISERS	0.09%	82.57K	465.7M	-11.71K	-12.42%
Dec 31, 2025	QUANTUM PRIVATE WEALTH, LLC	0.1%	94.23K	531.46K	0	0
Dec 31, 2025	MONASHEE INVESTMENT MANAGEMENT LLC	1.43%	1.35M	7.61M	1.35M	+100.00%
Dec 31, 2025	FRANKLIN RESOURCES INC	1.69%	1.6M	9.02M	1	0.00%
Dec 31, 2025	LEGAL & GENERAL GROUP PLC	0.01%	5.27K	29.72K	0	0
Dec 31, 2025	GROUP ONE TRADING, L.P.	0.01%	6.55K	36.96K	1.8K	+37.96%
Dec 31, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.01%	7.1K	40.04K	0	0
Dec 31, 2025	MARTINGALE ASSET MANAGEMENT L P	0.01%	10.57K	59.64K	346	+3.38%
Dec 31, 2025	STATE STREET CORP	1.15%	1.09M	6.13M	-5.89K	-0.54%
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.34%	1.27M	7.15M	-19.85K	-1.54%
Dec 31, 2025	NANTAHALA CAPITAL MANAGEMENT, LLC	1.7%	1.6M	9.04M	-95.92K	-5.64%
Dec 31, 2025	VANGUARD GROUP INC	3.66%	3.45M	19.49M	371.11K	+12.03%
Dec 31, 2025	BLACKROCK, INC.	5.16%	4.87M	27.47M	144.56K	+3.06%
Dec 31, 2025	ALYESKA INVESTMENT GROUP, L.P.	1.78%	1.68M	9.49M	0	0
Dec 31, 2025	AMERICAN CENTURY COMPANIES INC	0.1%	97.32K	548.9K	26.27K	+36.97%
Sep 30, 2025	SIREN, L.L.C.	7.88%	7.42M	45.76M	0	0
Sep 30, 2025	RA CAPITAL MANAGEMENT, L.P.	6.17%	5.81M	35.86M	100	0.00%
Sep 30, 2025	BLACKROCK, INC.	5.02%	4.73M	29.15M	-194.97K	-3.96%
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.49%	463.7K	2.86M	463.7K	+100.00%
Sep 30, 2025	VANGUARD GROUP INC	3.28%	3.08M	19.03M	-281.7K	-8.37%
Sep 30, 2025	FMR LLC	3.1%	2.91M	17.98M	-264.27K	-8.31%
Sep 30, 2025	REDMILE GROUP, LLC	2.02%	1.9M	11.72M	-16.58K	-0.87%
Sep 30, 2025	NANTAHALA CAPITAL MANAGEMENT, LLC	1.81%	1.7M	10.48M	-4.08K	-0.24%
Sep 30, 2025	ALYESKA INVESTMENT GROUP, L.P.	1.79%	1.68M	10.38M	41.98K	+2.56%
Sep 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	1.42%	1.33M	8.22M	66.95K	+5.29%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.37%	1.29M	7.94M	-222.91K	-14.76%
Sep 30, 2025	STATE STREET CORP	1.16%	1.09M	6.75M	141.85K	+14.91%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.84%	790K	4.87M	-34.6K	-4.20%
Sep 30, 2025	BALYASNY ASSET MANAGEMENT L.P.	0.78%	732.61K	4.52M	245.49K	+50.39%
Sep 30, 2025	BOXER CAPITAL MANAGEMENT, LLC	0.64%	600K	3.7M	600K	+100.00%
Sep 30, 2025	ALLY BRIDGE GROUP (NY) LLC	0.58%	549.18K	3.39M	-174.82K	-24.15%
Sep 30, 2025	PANAGORA ASSET MANAGEMENT INC	0.42%	397.19K	2.45M	397.19K	+100.00%
Sep 30, 2025	BIRCHVIEW CAPITAL, LP	0.32%	296.96K	1.83M	118.19K	+66.11%
Sep 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.24%	226.4K	1.4M	90.64K	+66.76%
Sep 30, 2025	SUSQUEHANNA PORTFOLIO STRATEGIES, LLC	0.21%	199.44K	1.23M	0	0
Sep 30, 2025	APIS CAPITAL ADVISORS, LLC	0.21%	196K	1.21M	-4K	-2.00%
Sep 30, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.2%	186.6K	1.15M	186.6K	+100.00%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.17%	162.06K	999.9K	-49.02K	-23.22%
Sep 30, 2025	BIOIMPACT CAPITAL LLC	1.74%	1.63M	10.09M	0	0
Sep 30, 2025	NORTHERN TRUST CORP	0.47%	446.52K	2.76M	-50.82K	-10.22%
Sep 30, 2025	VESTAL POINT CAPITAL, LP	3.16%	2.98M	18.36M	1.47M	+97.67%
Sep 30, 2025	FRANKLIN RESOURCES INC	1.7%	1.6M	9.87M	59	0.00%
Sep 30, 2025	FINEPOINT CAPITAL LP	1.02%	961.25K	5.93M	0	0
Sep 30, 2025	CITADEL ADVISORS LLC	2.75%	2.59M	16M	69.4K	+2.75%
Sep 30, 2025	UBS GROUP AG	0.77%	724.15K	4.47M	-48.15K	-6.23%
Sep 30, 2025	PARKMAN HEALTHCARE PARTNERS LLC	0.42%	396.4K	2.45M	396.4K	+100.00%
Sep 30, 2025	NUVEEN, LLC	0.42%	394.98K	2.44M	-12.87K	-3.16%
Sep 30, 2025	ROYAL BANK OF CANADA	0.4%	378.24K	2.33M	-5.42K	-1.41%
Sep 30, 2025	SIMPLEX TRADING, LLC	0.09%	84K	518K	84K	+100.00%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.08%	73.03K	450.6K	61.84K	+552.58%
Sep 30, 2025	AMERICAN CENTURY COMPANIES INC	0.08%	71.05K	438.39K	59.35K	+507.43%
Sep 30, 2025	PRUDENTIAL FINANCIAL INC	0.06%	60.99K	376.31K	60.99K	+100.00%
Sep 30, 2025	NISA INVESTMENT ADVISORS, LLC	0.06%	60.54K	373.51K	56.7K	+1,478.10%
Sep 30, 2025	DEUTSCHE BANK AG\	0.06%	52.16K	321.83K	6.58K	+14.42%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0.05%	45.21K	278.93K	2.85K	+6.72%
Sep 30, 2025		0.04%	36.89K	227.58K	36.89K	+100.00%
Sep 30, 2025	JPMORGAN CHASE & CO	0.04%	35.7K	220.29K	1.32K	+3.85%
Sep 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.03%	29.95K	184.77K	-6.42K	-17.64%
Sep 30, 2025	SFMG, LLC	0.03%	25.03K	154.44K	0	0
Sep 30, 2025	AXQ CAPITAL, LP	0.03%	24.04K	148.3K	24.04K	+100.00%
Sep 30, 2025	HSBC HOLDINGS PLC	0.03%	23.59K	138.25K	-1.79K	-7.04%
Sep 30, 2025	DYNAMIC TECHNOLOGY LAB PRIVATE LTD	0.03%	23.58K	145K	602	+2.62%
Sep 30, 2025	FOX RUN MANAGEMENT, L.L.C.	0.02%	18.51K	114.23K	18.51K	+100.00%
Sep 30, 2025	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0.02%	17.39K	107.29K	2.28K	+15.06%
Sep 30, 2025	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.01%	13.65K	84.21K	-1.92K	-12.33%
Sep 30, 2025	SEI INVESTMENTS CO	0.01%	13.08K	80.69K	0	0
Sep 30, 2025	PROSHARE ADVISORS LLC	0.01%	12.86K	79.32K	-3.58K	-21.76%
Sep 30, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.01%	11.16K	68.86K	-7.09K	-38.84%
Sep 30, 2025	PALLAS CAPITAL ADVISORS LLC	0.01%	11.15K	68.77K	103	+0.93%
Sep 30, 2025	COMMONWEALTH EQUITY SERVICES, LLC	0.01%	10.85K	67K	10.85K	+100.00%
Sep 30, 2025	MARTINGALE ASSET MANAGEMENT L P	0.01%	10.23K	63.11M	8	+0.08%
Sep 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0.01%	10.21K	63K	5.99K	+141.97%
Sep 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.01%	7.1K	43.81K	0	0
Sep 30, 2025	CITIGROUP INC	0.01%	6.19K	38.21K	-46.18K	-88.18%
Sep 30, 2025	LEGAL & GENERAL GROUP PLC	0.01%	5.27K	32.52K	-741	-12.33%
Sep 30, 2025	STEWARD PARTNERS INVESTMENT ADVISORY, LLC	0.01%	4.96K	30.57K	0	0
Sep 30, 2025	AMERITAS INVESTMENT PARTNERS, INC.	0.01%	4.93K	30.39K	-1.81K	-26.91%
Sep 30, 2025	GROUP ONE TRADING, L.P.	0.01%	4.75K	29.31M	4.75K	+100.00%
Sep 30, 2025	MORGAN STANLEY	0.27%	257.85K	1.59M	22.2K	+9.42%
Sep 30, 2025	IKARIAN CAPITAL, LLC	0.19%	176.69K	1.09M	176.69K	+100.00%
Sep 30, 2025	KNOTT DAVID M JR	0.17%	162.44K	1M	0	0
Sep 30, 2025	ARMISTICE CAPITAL, LLC	0.99%	936K	5.78M	536K	+134.00%
Sep 30, 2025	MILLENNIUM MANAGEMENT LLC	0.97%	909.7K	5.61M	-189.67K	-17.25%
Sep 30, 2025	WOODLINE PARTNERS LP	0.67%	631.82K	3.9M	0	0
Sep 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.54%	503.67K	3.11M	154.8K	+44.37%
Sep 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	4.25%	4M	24.68M	-2.73M	-40.56%
Sep 30, 2025	DIMENSIONAL FUND ADVISORS LP	0.47%	443.54K	2.74M	221.2K	+99.49%
Sep 30, 2025	TWO SIGMA INVESTMENTS, LP	0.17%	155.85K	961.6K	-18.15K	-10.43%
Sep 30, 2025	BARCLAYS PLC	0.17%	159.1K	981.66K	-22.44K	-12.36%
Sep 30, 2025	HRT FINANCIAL LP	0.17%	156.82K	967K	156.82K	+100.00%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	0.72%	676.63K	4.17M	294.87K	+77.24%
Sep 30, 2025	SECTORAL ASSET MANAGEMENT INC	0.67%	633.05K	3.91M	211.47K	+50.16%
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.16%	148.66K	917.23K	-9.69K	-6.12%
Sep 30, 2025	INVESCO LTD.	0.12%	117.37K	724.16K	37K	+46.04%
Sep 30, 2025	SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC	0.12%	116.53K	718.96K	-25.03K	-17.68%
Sep 30, 2025	SKOPOS LABS, INC.	0.11%	99.59K	614.44K	99.59K	+100.00%
Sep 30, 2025	RHUMBLINE ADVISERS	0.1%	94.28K	581.71K	-7.89K	-7.72%
Sep 30, 2025	QUANTUM PRIVATE WEALTH, LLC	0.1%	94.23K	581.41K	3.5K	+3.86%
Sep 30, 2025	JANE STREET GROUP, LLC	0.1%	91.59K	565.09M	91.59K	+100.00%
Sep 30, 2025	PERCEPTIVE ADVISORS LLC	12.57%	11.83M	73.01M	-73.11K	-0.61%
Sep 30, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	8.4%	7.91M	48.81M	0	0
Jun 30, 2025	NORTHERN TRUST CORP	0.53%	497.34K	2.42M	319.44K	+179.56%
Jun 30, 2025	WOODLINE PARTNERS LP	0.67%	631.82K	3.08M	0	0
Jun 30, 2025	SIREN, L.L.C.	11.18%	7.42M	36.12M	0	0
Jun 30, 2025	MONASHEE INVESTMENT MANAGEMENT LLC	3.26%	2.17M	10.54M	491.59K	+29.38%
Jun 30, 2025	BOLLARD GROUP LLC	0.55%	361.66K	1.76M	361.66K	+100.00%
Jun 30, 2025	APIS CAPITAL ADVISORS, LLC	0.3%	200K	974K	90K	+81.82%
Jun 30, 2025	KNOTT DAVID M JR	0.24%	162.44K	791.08K	30.44K	+23.06%
Jun 30, 2025	SFMG, LLC	0.04%	25.03K	121.9K	0	0
Jun 30, 2025	PROSHARE ADVISORS LLC	0.02%	16.43K	80.02K	16.43K	+100.00%
Jun 30, 2025	SG AMERICAS SECURITIES, LLC	0.02%	13.09K	64K	13.09K	+100.00%
Jun 30, 2025	PALLAS CAPITAL ADVISORS LLC	0.02%	11.04K	53.78K	11.04K	+100.00%
Jun 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.01%	7.1K	35K	0	0
Jun 30, 2025	CWM, LLC	0.01%	5.43K	26K	-2.52K	-31.69%
Jun 30, 2025	NISA INVESTMENT ADVISORS, LLC	0.01%	3.84K	18.68K	-1.61K	-29.56%
Jun 30, 2025	MIRAE ASSET GLOBAL INVESTMENTS CO., LTD.	0%	2.99K	14.58K	504	+20.24%
Jun 30, 2025	STERLING CAPITAL MANAGEMENT LLC	0%	1.78K	8.68K	1.41K	+377.75%
Jun 30, 2025	HANTZ FINANCIAL SERVICES, INC.	0%	1K	5K	0	0
Jun 30, 2025	AMALGAMATED BANK	0%	779	4K	0	0
Jun 30, 2025	TRUE WEALTH DESIGN, LLC	0%	564	2.75K	246	+77.36%
Jun 30, 2025	PHYSICIAN WEALTH ADVISORS, INC.	0%	312	1.52K	312	+100.00%
Jun 30, 2025	US BANCORP \DE\	0%	300	1.46K	-36	-10.71%
Jun 30, 2025	ADVISOR GROUP HOLDINGS, INC.	0%	30	120K	0	0
Jun 30, 2025	CLEARSTEAD ADVISORS, LLC	0%	9	44	9	+100.00%
Jun 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0%	0	-	-175.4K	-100.00%
Jun 30, 2025	FEDERATED HERMES, INC.	0%	0	-	-2.4K	-100.00%
Jun 30, 2025	COLDSTREAM CAPITAL MANAGEMENT INC	0%	0	-	-685	-100.00%
Jun 30, 2025	MARSHALL WACE, LLP	0%	0	-	-336.33K	-100.00%
Jun 30, 2025	SIMPLEX TRADING, LLC	0%	0	-	-1.1K	-100.00%
Jun 30, 2025	FOX RUN MANAGEMENT, L.L.C.	0%	0	-	-38.23K	-100.00%
Jun 30, 2025	VIRTU FINANCIAL LLC	0%	0	-	-25.74K	-100.00%
Jun 30, 2025	GROUND SWELL CAPITAL, LLC	0%	0	-	-11.22K	-100.00%
Jun 30, 2025	ALLIANZ ASSET MANAGEMENT GMBH	0%	0	-	-27.1K	-100.00%
Jun 30, 2025	TREXQUANT INVESTMENT LP	0%	0	-	-167.03K	-100.00%
Jun 30, 2025	QUADRATURE CAPITAL LTD	0%	0	-	-37.33K	-100.00%
Jun 30, 2025	WALLEYE CAPITAL LLC	0%	0	-	-55.23K	-100.00%
Jun 30, 2025	XTX TOPCO LTD	0%	0	-	-40.93K	-100.00%
Jun 30, 2025	COREBRIDGE FINANCIAL, INC.	0%	0	-	-11.64K	-100.00%
Jun 30, 2025	PERCEPTIVE ADVISORS LLC	17.95%	11.91M	57.99M	0	0
Jun 30, 2025	WELLS FARGO & COMPANY/MN	0.06%	42.36K	206.3M	28.22K	+199.57%
Jun 30, 2025	JANE STREET GROUP, LLC	0.04%	27.6K	134.41M	16K	+137.93%
Jun 30, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.04%	24.41K	118.87M	24.41K	+100.00%
Jun 30, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.03%	18.25K	88.87M	18.25K	+100.00%
Jun 30, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	11.93%	7.91M	38.53M	0	0
Jun 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	10.14%	6.73M	32.77M	0	0
Jun 30, 2025	RA CAPITAL MANAGEMENT, L.P.	8.76%	5.81M	28.3M	1.48M	+34.20%
Jun 30, 2025	BIRCHVIEW CAPITAL, LP	0.27%	178.77K	870.6K	50K	+38.83%
Jun 30, 2025	POLAR ASSET MANAGEMENT PARTNERS INC.	0.07%	43.5K	211.85K	43.5K	+100.00%
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	0.05%	33.08K	162K	21.52K	+186.18%
Jun 30, 2025	BLACKROCK, INC.	5.23%	4.92M	23.96M	2.77M	+128.75%
Jun 30, 2025	AMERICAN CENTURY COMPANIES INC	0.01%	11.7K	56.96K	-40.14K	-77.43%
Jun 30, 2025	MARTINGALE ASSET MANAGEMENT L P	0.01%	10.22K	49.77K	10.22K	+100.00%
Jun 30, 2025	FMR LLC	3.38%	3.18M	15.48M	-339.49K	-9.65%
Jun 30, 2025	ALYESKA INVESTMENT GROUP, L.P.	1.74%	1.64M	7.99M	0	0
Jun 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	1.34%	1.27M	6.17M	1.06M	+528.57%
Jun 30, 2025	ROYAL BANK OF CANADA	0.41%	383.66K	1.87M	382.3K	+28,234.93%
Jun 30, 2025	BALYASNY ASSET MANAGEMENT L.P.	0.52%	487.12K	2.37M	-140.15K	-22.34%
Jun 30, 2025		0.43%	407.84K	1.99M	364.27K	+835.87%
Jun 30, 2025	MORGAN STANLEY	0.36%	235.65K	1.15B	-118.07K	-33.38%
Jun 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.05%	36.36K	177.08K	18.62K	+104.94%
Jun 30, 2025	CIBC PRIVATE WEALTH GROUP, LLC	0.03%	30.6K	149.02K	0	0
Jun 30, 2025	BIOIMPACT CAPITAL LLC	2.46%	1.63M	7.96M	-7.79K	-0.47%
Jun 30, 2025	AQR CAPITAL MANAGEMENT LLC	0.2%	130.08K	633.51M	16.99K	+15.02%
Jun 30, 2025	ALLIANCEBERNSTEIN L.P.	0.12%	81.83K	398.51M	66.23K	+424.55%
Jun 30, 2025	MIRAE ASSET GLOBAL ETFS HOLDINGS LTD.	0.04%	36.14K	176.02K	22.66K	+168.12%
Jun 30, 2025	HSBC HOLDINGS PLC	0.04%	25.38K	125.88K	6.31K	+33.10%
Jun 30, 2025	DYNAMIC TECHNOLOGY LAB PRIVATE LTD	0.03%	22.98K	112K	22.98K	+100.00%
Jun 30, 2025	LIDO ADVISORS, LLC	0.02%	20.19K	98.32K	0	0
Jun 30, 2025	MARINER, LLC	0.02%	19.41K	94.55K	19.41K	+100.00%
Jun 30, 2025	VESTAL POINT CAPITAL, LP	2.27%	1.51M	7.33M	-248.56K	-14.17%
Jun 30, 2025	FINEPOINT CAPITAL LP	1.45%	961.25K	4.68M	0	0
Jun 30, 2025	ALLY BRIDGE GROUP (NY) LLC	1.09%	724K	3.53M	724K	+100.00%
Jun 30, 2025	SECTORAL ASSET MANAGEMENT INC	0.64%	421.58K	2.05M	421.58K	+100.00%
Jun 30, 2025	ARMISTICE CAPITAL, LLC	0.6%	400K	1.95M	400K	+100.00%
Jun 30, 2025	SUSQUEHANNA PORTFOLIO STRATEGIES, LLC	0.3%	199.44K	971.25K	183.14K	+1,123.83%
Jun 30, 2025	SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC	0.21%	141.55K	689.36K	0	0
Jun 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.14%	135.76K	661.16K	135.76K	+100.00%
Jun 30, 2025	QUANTUM PRIVATE WEALTH, LLC	0.14%	90.73K	441.86K	19.9K	+28.09%
Jun 30, 2025	RHUMBLINE ADVISERS	0.11%	102.17K	497.56K	62.75K	+159.17%
Jun 30, 2025	INVESCO LTD.	0.09%	80.37K	391.39K	40.19K	+100.02%
Jun 30, 2025	CITADEL ADVISORS LLC	3.8%	2.52M	12.29B	637.41K	+33.80%
Jun 30, 2025	VANGUARD GROUP INC	3.58%	3.37M	16.39M	905.1K	+36.79%
Jun 30, 2025	REDMILE GROUP, LLC	2.89%	1.92M	9.33M	-103.25K	-5.11%
Jun 30, 2025	NANTAHALA CAPITAL MANAGEMENT, LLC	2.57%	1.7M	8.3M	1.42M	+505.38%
Jun 30, 2025	FRANKLIN RESOURCES INC	1.7%	1.6M	7.79M	358.47K	+28.89%
Jun 30, 2025	MILLENNIUM MANAGEMENT LLC	1.17%	1.1M	5.35M	564.81K	+105.66%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.6%	1.51M	7.36M	979.29K	+184.47%
Jun 30, 2025	STATE STREET CORP	1.01%	951.45K	4.63M	515.18K	+118.08%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0.88%	824.6K	4.02M	787.96K	+2,150.36%
Jun 30, 2025	UBS GROUP AG	0.82%	772.3K	3.76M	657.6K	+573.35%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.58%	381.76K	1.86B	201.62K	+111.92%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.37%	348.86K	1.7M	151.08K	+76.38%
Jun 30, 2025	BARCLAYS PLC	0.27%	181.55K	884K	120.86K	+199.13%
Jun 30, 2025	BLAIR WILLIAM & CO/IL	0.25%	165.7K	806.96K	165.7K	+100.00%
Jun 30, 2025	DIMENSIONAL FUND ADVISORS LP	0.24%	222.34K	1.08M	-47.14K	-17.49%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.22%	211.07K	1.03M	142.47K	+207.66%
Jun 30, 2025	TWO SIGMA INVESTMENTS, LP	0.18%	174K	847.38K	104.51K	+150.38%
Jun 30, 2025	JUMP FINANCIAL, LLC	0.17%	115.76K	563.76K	39.44K	+51.68%
Jun 30, 2025	BANK OF NEW YORK MELLON CORP	0.17%	158.35K	771.18K	106.04K	+202.72%
Jun 30, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.15%	98.53K	479.85K	15K	+17.96%
Jun 30, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.08%	50.19K	244.43K	50.19K	+100.00%
Jun 30, 2025	NUVEEN, LLC	0.43%	407.84K	1.99M	364.27K	+835.87%
Mar 31, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	10.14%	6.73M	24.9M	4.98M	+284.96%
Mar 31, 2025	BIRCHVIEW CAPITAL, LP	0.19%	128.77K	476.44K	128.77K	+100.00%
Mar 31, 2025	NORTHERN TRUST CORP	0.27%	177.9K	658.22K	8.8K	+5.20%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.27%	180.14K	666.51K	43.91K	+32.23%
Mar 31, 2025	STATE STREET CORP	0.66%	436.28K	1.61M	4.1K	+0.95%
Mar 31, 2025	DIMENSIONAL FUND ADVISORS LP	0.41%	269.48K	998.18K	5.41K	+2.05%
Mar 31, 2025	JUMP FINANCIAL, LLC	0.12%	76.32K	282.38K	76.32K	+100.00%
Mar 31, 2025	WOODLINE PARTNERS LP	0.95%	631.82K	2.34M	631.82K	+100.00%
Mar 31, 2025	CASDIN CAPITAL, LLC	1.17%	775K	2.87M	775K	+100.00%
Mar 31, 2025	FINEPOINT CAPITAL LP	1.45%	961.25K	3.56M	0	0
Mar 31, 2025		1.87%	1.24M	4.59M	1.24M	+100.00%
Mar 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.3%	197.79K	731.82K	144.8K	+273.28%
Mar 31, 2025	LOGOS GLOBAL MANAGEMENT LP	0.15%	100K	370K	100K	+100.00%
Mar 31, 2025	ECOR1 CAPITAL, LLC	1.12%	744.45K	2.75M	744.45K	+100.00%
Mar 31, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.17%	69.87K	258.53K	69.87K	+100.00%
Mar 31, 2025	RA CAPITAL MANAGEMENT, L.P.	6.53%	4.33M	16.02M	0	0
Mar 31, 2025	AMERICAN CENTURY COMPANIES INC	0.13%	51.84K	191.79K	4.98K	+10.62%
Mar 31, 2025	WALLEYE CAPITAL LLC	0.14%	55.23K	204.35K	-103.6K	-65.23%
Mar 31, 2025	SQUAREPOINT OPS LLC	0.16%	105.68K	391.02K	105.68K	+100.00%
Mar 31, 2025	UBS GROUP AG	0.17%	114.7K	424.37K	20.23K	+21.41%
Mar 31, 2025	STEMPOINT CAPITAL LP	0.3%	198.15K	733.16K	198.15K	+100.00%
Mar 31, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.3%	201.42K	745.25K	201.42K	+100.00%
Mar 31, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.68%	452.24K	1.67M	452.24K	+100.00%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.8%	530.86K	1.96M	21.06K	+4.13%
Mar 31, 2025	FRANKLIN RESOURCES INC	1.87%	1.24M	4.59M	1.24M	+100.00%
Mar 31, 2025	ALYESKA INVESTMENT GROUP, L.P.	2.47%	1.64M	6.07M	1.29M	+373.72%
Mar 31, 2025	FMR LLC	5.3%	3.52M	13.02M	3.47M	+7,432.14%
Mar 31, 2025	APIS CAPITAL ADVISORS, LLC	0.17%	110K	407K	110K	+100.00%
Mar 31, 2025	AQR CAPITAL MANAGEMENT LLC	0.17%	113.1K	418.47K	113.1K	+100.00%
Mar 31, 2025	KNOTT DAVID M JR	0.2%	132K	488.4K	132K	+100.00%
Mar 31, 2025	SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC	0.21%	141.55K	523.74K	141.55K	+100.00%
Mar 31, 2025	RESOLUTE CAPITAL ASSET PARTNERS LLC	0.23%	150K	555K	150K	+100.00%
Mar 31, 2025	TREXQUANT INVESTMENT LP	0.25%	167.03K	618.02K	-27.25K	-14.03%
Mar 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0.26%	175.4K	648.98K	92.91K	+112.62%
Mar 31, 2025	IKARIAN CAPITAL, LLC	0.35%	230K	851K	230K	+100.00%
Mar 31, 2025	NANTAHALA CAPITAL MANAGEMENT, LLC	0.42%	281.37K	1.04M	281.37K	+100.00%
Mar 31, 2025	MARSHALL WACE, LLP	0.51%	336.33K	1.24M	154.82K	+85.30%
Mar 31, 2025	BIOIMPACT CAPITAL LLC	2.48%	1.64M	6.08M	1.64M	+100.00%
Mar 31, 2025	VESTAL POINT CAPITAL, LP	2.64%	1.75M	6.49M	-1.1M	-38.47%
Mar 31, 2025	CITADEL ADVISORS LLC	2.84%	1.89M	6.98M	937.47K	+98.85%
Mar 31, 2025	REDMILE GROUP, LLC	3.04%	2.02M	7.47M	1.4M	+228.19%
Mar 31, 2025	BLACKROCK, INC.	3.24%	2.15M	7.96M	290.27K	+15.60%
Mar 31, 2025	VANGUARD GROUP INC	3.71%	2.46M	9.1M	1.06M	+75.59%
Mar 31, 2025	COMMODORE CAPITAL LP	8.78%	5.83M	21.55M	5.83M	+100.00%
Mar 31, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	11.93%	7.91M	29.27M	3.88M	+96.10%
Mar 31, 2025	SIREN, L.L.C.	11.18%	7.42M	27.44M	3.67M	+97.81%
Mar 31, 2025	PERCEPTIVE ADVISORS LLC	17.95%	11.91M	44.05M	5M	+72.39%
Mar 31, 2025	QUANTUM PRIVATE WEALTH, LLC	0.17%	70.83K	262.08K	13.5K	+23.55%
Mar 31, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.13%	83.53K	309.07K	-19.1K	-18.61%
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	0.81%	534.56K	1.98M	-185.21K	-25.73%
Mar 31, 2025	MONASHEE INVESTMENT MANAGEMENT LLC	2.52%	1.67M	6.19M	1.19M	+248.63%
Mar 31, 2025	BALYASNY ASSET MANAGEMENT L.P.	0.95%	627.27K	2.32M	627.27K	+100.00%
Mar 31, 2025	VR ADVISER, LLC	3.74%	2.48M	9.18M	2.48M	+100.00%
Mar 31, 2025	MORGAN STANLEY	0.53%	353.72K	1.31M	275.74K	+353.59%
Mar 31, 2024	PARALLEL ADVISORS, LLC	0%	6	80	0	0
Dec 31, 2023	PARALLEL ADVISORS, LLC	0%	6	37	0	0
Sep 30, 2023	BAKER AVENUE ASSET MANAGEMENT, LP	0%	0	-	-66	-100.00%
Sep 30, 2023	PARALLEL ADVISORS, LLC	0%	6	15	0	0

Insiders

Among the SLDB insiders holding of 0.56% of the stake in company, PERCEPTIVE ADVISORS LLC, , holds the largest shares of 11.83M. BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC, 10 percent owner, is the second largest SLDB insider with ownership of 5.03M shares. ADAGE CAPITAL MANAGEMENT, L.P., 10 percent owner, stands third with possession of 4.25M shares of that stake.

Insiders	Designation	Shares Held
PERCEPTIVE ADVISORS LLC		11.83M
BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	10 percent owner	5.03M
ADAGE CAPITAL MANAGEMENT, L.P.	10 percent owner	4.25M
RA CAPITAL MANAGEMENT, L.P.	10 percent owner	3.72M
BOXER CAPITAL, LLC	10 percent owner	3.47M
ARNOLD MATTHEW BENNETT	director	3.39M
SHAH RAJEEV M.	director	2.69M
KOPPEL ADAM	director	1.99M
ZIOLKOWSKI JENNIFER LYNN	CFO, Treasurer & Asst. Secy	335.64K
SCHNEIDER JOEL SOLOMON ZEV	Chief Operating Officer	251.54K
CUMBO ALEXANDER	President and CEO	235.41K
QUIROZ JORGE ARMANDO	Chief Medical Officer	228.09K
HERSCHA LYNETTE	Chief Legal Officer	160.86K
AMORRORTU PEDRO ALVARO	Chief Operating Officer	158.05K
HOWTON DAVID T	Chief Operating Officer	105.08K
TAN KEVIN	CFO & Treasurer	99.42K
BROOKS GABRIEL	Chief Medical Officer	89.47K
HANRAHAN JESSIE	Chief Regulatory Officer	74.32K
HERZICH PAUL	Chief Technology Officer	72.64K
GANOT ILAN	director	27.47K
MORRIS CARL ASHLEY	Chief Scientific Officer	19.76K
ZARUR JUAN ANDREY	director	10.19K
MARLOWE JENNIFER	CSO	7K
KAHN CLARE	director	2.96K

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Feb 18, 2026	HERZICH PAUL	SALE	5.82	3.62K	21.06K	72.64K
Feb 18, 2026	TAN KEVIN	SALE	5.82	5.4K	31.47K	99.42K
Feb 18, 2026	BROOKS GABRIEL	SALE	5.82	0	-	89.47K
Feb 18, 2026	HOWTON DAVID T	SALE	5.82	7.47K	43.49K	105.08K
Feb 18, 2026	CUMBO ALEXANDER	SALE	5.82	16.64K	96.92K	235.41K
Feb 18, 2026	HANRAHAN JESSIE	SALE	5.82	4.13K	24.07K	74.32K
Feb 18, 2026	GANOT ILAN	SALE	5.82	2.66K	15.48K	27.47K
Feb 04, 2026	BROOKS GABRIEL	SALE	6.44	12.62K	81.27K	84.09K
Feb 04, 2026	TAN KEVIN	SALE	6.44	14.78K	95.23K	94.2K
Feb 04, 2026	GANOT ILAN	SALE	6.44	7.21K	46.41K	25.27K
Feb 04, 2026	CUMBO ALEXANDER	SALE	6.44	48.91K	315.09K	222.02K
Feb 04, 2026	HOWTON DAVID T	SALE	6.44	18.89K	121.71K	97.86K
Feb 04, 2026	HERZICH PAUL	SALE	6.44	10.91K	70.25K	69.07K
Feb 04, 2026	HANRAHAN JESSIE	SALE	6.44	12.35K	79.54K	70.33K
Feb 02, 2026	HANRAHAN JESSIE	SALE	6.44	26.54K	170.8K	82.68K
Feb 02, 2026	TAN KEVIN	SALE	6.44	26.84K	172.75K	108.98K
Feb 02, 2026	BROOKS GABRIEL	SALE	6.44	28.34K	182.39K	96.71K
Feb 02, 2026	HOWTON DAVID T	SALE	6.44	37.77K	243.13K	116.75K
Feb 02, 2026	CUMBO ALEXANDER	SALE	6.44	80.26K	516.61K	270.93K
Feb 02, 2026	HERZICH PAUL	SALE	6.44	26.25K	168.97K	79.97K
Jan 28, 2026	GANOT ILAN	SALE	6.59	191	1.26K	17.48K
Jan 13, 2026	TAN KEVIN	SALE	5.27	5.7K	30.06K	46.1K
Jan 05, 2026	GANOT ILAN	SALE	5.43	1.05K	5.72K	17.28K
Dec 03, 2025	HOWTON DAVID T	SALE	5.11	4.93K	25.2K	32.91K
Dec 03, 2025	CUMBO ALEXANDER	SALE	5.11	10.81K	55.23K	81.39K
Dec 03, 2025	HANRAHAN JESSIE	SALE	5.11	4.48K	22.91K	26.66K
Dec 03, 2025	HERZICH PAUL	SALE	5.11	2.7K	13.8K	26.62K
Nov 10, 2025	GANOT ILAN	SALE	4.12	3.28K	13.51K	95.41K
Oct 20, 2025	BROOKS GABRIEL	SALE	5.96	2.9K	17.25K	33.82K
Mar 11, 2025	KAHN CLARE	PURCHASE	5.34	1.86K	9.92K	2.96K
Feb 19, 2025	PERCEPTIVE ADVISORS LLC	PURCHASE	4.03	5M	20.15M	11.83M
Feb 19, 2025	RA CAPITAL MANAGEMENT, L.P.	PURCHASE	0.00	3.72M	3.72K	3.72M
Feb 19, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	PURCHASE	4.03	1M	4.03M	5.03M
Feb 18, 2025	ADAGE CAPITAL MANAGEMENT, L.P.	PURCHASE	7.56	252.55K	1.91M	4.25M
Feb 14, 2025	CUMBO ALEXANDER	SALE	3.96	11.37K	45.01K	60.72K
Feb 14, 2025	HERZICH PAUL	SALE	3.96	2.69K	10.64K	18.39K
Feb 14, 2025	HOWTON DAVID T	SALE	3.96	5.56K	22.02K	24.79K
Feb 14, 2025	TAN KEVIN	SALE	3.96	3.16K	12.53K	32.25K
Feb 14, 2025	BROOKS GABRIEL	SALE	3.96	3.26K	12.89K	22.81K
Feb 14, 2025	HANRAHAN JESSIE	SALE	3.96	3.08K	12.19K	19.28K
Feb 14, 2025	GANOT ILAN	SALE	3.96	1.71K	6.78K	14.84K
Jan 28, 2025	GANOT ILAN	SALE	3.11	144	447.78	11.69K
Jan 10, 2025	TAN KEVIN	SALE	3.89	4.07K	15.85K	24.79K
Jan 06, 2025	GANOT ILAN	SALE	4.31	1.06K	4.55K	11.45K
Dec 03, 2024	CUMBO ALEXANDER	SALE	5.60	11.11K	62.24K	38.48K
Dec 03, 2024	HOWTON DAVID T	SALE	5.60	5.07K	28.4K	15.66K
Dec 03, 2024	HANRAHAN JESSIE	SALE	5.60	4.61K	25.82K	14.24K
Dec 03, 2024	HERZICH PAUL	SALE	5.60	2.78K	15.55K	12.18K
Oct 21, 2024	BROOKS GABRIEL	SALE	6.50	2.92K	19K	10.98K
Jun 07, 2024	KAHN CLARE	PURCHASE	7.67	1.1K	8.44K	1.1K
May 02, 2024	GANOT ILAN	SALE	10.33	462	4.77K	9.51K
Jan 29, 2024	GANOT ILAN	SALE	7.99	139	1.11K	8.42K
Jan 11, 2024	PERCEPTIVE ADVISORS LLC	PURCHASE	5.53	3.41M	18.86M	6.83M
Jan 11, 2024	RA CAPITAL MANAGEMENT, L.P.	PURCHASE	5.53	904.16K	5M	4.19M
Jan 09, 2024	TAN KEVIN	SALE	8.20	3.94K	32.27K	9.31K
Jan 03, 2024	GANOT ILAN	SALE	5.30	1.14K	6.05K	8.17K
Dec 04, 2023	CUMBO ALEXANDER	SALE	2.77	11.76K	32.52K	17.44K
Dec 04, 2023	HOWTON DAVID T	SALE	2.78	5.37K	14.92K	7.68K
Dec 04, 2023	HERZICH PAUL	SALE	2.77	2.97K	8.23K	4.27K
Dec 04, 2023	HANRAHAN JESSIE	SALE	2.78	4.88K	13.56K	6.98K
Dec 04, 2023	MARLOWE JENNIFER	SALE	2.77	4.89K	13.52K	7K
May 02, 2023	GANOT ILAN	SALE	4.85	487	2.36K	4.15K
Jan 27, 2023	MORRIS CARL ASHLEY	SALE	7.49	441	3.3K	19.76K
Jan 27, 2023	GANOT ILAN	SALE	7.49	141	1.06K	1.38K
Mar 14, 2022	MORRIS CARL ASHLEY	SALE	1.10	11.4K	12.54K	255.21K
Mar 14, 2022	SCHNEIDER JOEL SOLOMON ZEV	SALE	1.10	15.23K	16.76K	251.54K
Feb 10, 2022	GANOT ILAN	SALE	1.12	463	518.65	2.52K
Mar 23, 2021	PERCEPTIVE ADVISORS LLC	PURCHASE	5.75	2.61M	15M	13.41M
Mar 19, 2021	RA CAPITAL MANAGEMENT, L.P.	PURCHASE	5.75	2.21M	12.69M	10.92M
Mar 12, 2021	MORRIS CARL ASHLEY	SALE	8.85	11.7K	103.49K	275.6K
Mar 12, 2021	SCHNEIDER JOEL SOLOMON ZEV	SALE	8.84	11.7K	103.45K	268.77K
Feb 12, 2021	GANOT ILAN	SALE	7.66	457	3.5K	3.03K
Jan 28, 2021	SCHNEIDER JOEL SOLOMON ZEV	SALE	6.14	3.44K	21.15K	292.17K
Jan 28, 2021	ZIOLKOWSKI JENNIFER LYNN	SALE	6.14	3.47K	21.33K	335.64K
Jan 28, 2021	GANOT ILAN	SALE	6.14	10.71K	65.78K	1.2M
Jan 28, 2021	MORRIS CARL ASHLEY	SALE	6.14	3.46K	21.24K	299K
Aug 13, 2020	GANOT ILAN	SALE	2.44	299	729.83	3.48K
Jul 28, 2020	MORRIS CARL ASHLEY	SALE	2.42	3.59K	8.69K	290.96K
Jul 28, 2020	GANOT ILAN	SALE	2.42	11.12K	26.91K	1.15M
Jul 28, 2020	HERSCHA LYNETTE	SALE	2.42	5.14K	12.44K	160.86K
Jul 28, 2020	ZIOLKOWSKI JENNIFER LYNN	SALE	2.42	3.59K	8.69K	327.61K
Jul 28, 2020	SCHNEIDER JOEL SOLOMON ZEV	SALE	2.42	4.04K	9.78K	284.12K
Jul 25, 2019	PERCEPTIVE ADVISORS LLC	PURCHASE	4.65	2.82M	13.13M	6.75M
May 08, 2019	ZARUR JUAN ANDREY	SALE	10.00	8K	80.04K	10.19K
Mar 28, 2019	BOXER CAPITAL, LLC	SALE	9.53	60K	571.8K	3.47M
Mar 27, 2019	BOXER CAPITAL, LLC	SALE	9.60	115K	1.1M	3.53M
Mar 26, 2019	BOXER CAPITAL, LLC	SALE	10.08	275K	2.77M	3.65M
Jan 14, 2019	ARNOLD MATTHEW BENNETT	SALE	32.20	3.3K	106.26K	3.39M
Jan 07, 2019	ARNOLD MATTHEW BENNETT	SALE	30.08	5K	150.41K	3.39M
Jan 04, 2019	AMORRORTU PEDRO ALVARO	SALE	30.07	9K	270.62K	158.05K
Dec 03, 2018	AMORRORTU PEDRO ALVARO	SALE	32.38	300	9.71K	167.05K
Dec 03, 2018	QUIROZ JORGE ARMANDO	SALE	32.24	1.37K	44.17K	228.09K
Nov 16, 2018	QUIROZ JORGE ARMANDO	SALE	34.90	100	3.49K	268.24K
Nov 16, 2018	ZARUR JUAN ANDREY	SALE	35.00	100	3.5K	691.11K
Nov 15, 2018	GANOT ILAN	SALE	31.06	19.1K	593.32K	1.1M
Nov 15, 2018	AMORRORTU PEDRO ALVARO	SALE	31.08	4.3K	133.63K	171.75K
Nov 15, 2018	SCHNEIDER JOEL SOLOMON ZEV	SALE	31.10	8.54K	265.62K	126.66K
Jan 30, 2018	SHAH RAJEEV M.	PURCHASE	16.00	1M	16M	2.69M
Jan 30, 2018	PERCEPTIVE ADVISORS LLC	PURCHASE	16.00	1M	16M	3.91M
Jan 30, 2018	KOPPEL ADAM	PURCHASE	16.00	300K	4.8M	1.99M

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES427.62K29

NET SHARES-427.62K29

SHARES HELD2.5M29

% NET SHARES-117.1%0%

Frequently Asked Questions