Stock Forecast Chart
Stock Price Prediction Summary
Forecast Score Based on 2 Weeks
Based on our forecast, the price of SION will decline by -100.00% over the next 2 Weeks and hit $0.00 by Wednesday, September 23, 2026. In that time frame, SION's share price is expected to range between $0.00 and $3.64.
BearishAverageBullish| Date | Predicted Lower | Predicted | Predicted Upper |
|---|---|---|---|
| Sep 23, 2026 | 0.00 | 0.00 | 3.64 |
| Sep 22, 2026 | 0.00 | 0.00 | 3.92 |
| Sep 21, 2026 | 0.00 | 0.00 | 3.01 |
| Sep 18, 2026 | 0.00 | 0.00 | 11.78 |
| Sep 17, 2026 | 0.00 | 0.00 | 12.37 |
| Sep 16, 2026 | 0.00 | 0.00 | 11.43 |
| Sep 15, 2026 | 0.00 | 0.00 | 12.60 |
| Sep 14, 2026 | 0.00 | 0.00 | 12.36 |
| Sep 11, 2026 | 0.00 | 7.63 | 21.47 |
| Sep 10, 2026 | 0.00 | 7.15 | 20.70 |
SION shares rose +1.87% in Thursday, September 10, 2026's trading session, rising from a previous close of $7.48 to move at $7.62. The stock demonstrated notable intraday movement (see SION's key stats for a full breakdown), fluctuating between $7.12 and $7.75, a +8.85% trading range. While recent weeks have seen some volatility, SION has managed to secure a +25.74% gain over the past 2 weeks. The upward price movement was accompanied by increased trading volume, with approximately 1.22M shares changing hands, 456.34K more than the previous session. This amounted to $9.32M in total market activity.
Will SION Continue Its Downward Trend?
According to analyst ratings and projections for SION, Sionna Therapeutics, Inc. shares are anticipated to decrease by -109.24%, potentially reaching $3.64 per share by September 23, 2026. Short-term technical indicators currently suggest a bearish sentiment for SION. However, the stock has recorded 20 positive trading days within the past 30 sessions. Based on the SION stock forecast, now is not the best time to buy SION stock because its current trading price is - our predicted value, hinting at a possible . For deeper insights, view our sentiment analysis on SION covering social and institutional perspectives.
SION Technical Momentum: Overbought, Oversold, or Neutral?
An analysis of Relative Strength Index (RSI) indicators provides insight into SION's momentum. Short-term RSIs (9, 14, and 20-day figures ranging from 30.66% to 36.02%) suggest the stock is in a weak bearish momentum phase. The 50-day RSI, at 36.74%, hints at potential weakness developing in the medium term. Additionally, the 100-day RSI, at 41.65%, maintains a neutral outlook for the long term. Insights into SION's shareholder base show how institutional investors are positioning themselves during these momentum shifts
Sionna Therapeutics Short-Term Forecasts
SION Forecast For Next 5 Days
Our algorithm anticipates Sionna Therapeutics (SION) stock could hit $2.22 by Sep 17, 2026. This represents a -70.82% rise from today's price, following a +10.10% change over the past five days.
SION Forecast For Next 30 Days
Based on analysis of market trends, the outlook for Sionna Therapeutics, Inc. (SION) stock over the next 30 days is largely negative. Price forecasts suggest an average target of $1.25, which would mean a -83.60% decrease from the current price of $7.62. Projections for this period range from a high of $13.75 to a low of $0.00.
SION Forecast For Next 90 Days
Our proprietary market analysis suggests predictions for Sionna Therapeutics's price over the next three months point to a rise. SION stock is expected to peak at $87.40 on Nov 27, 2026 after potentially dipping to $13.37 on Sep 10, 2026. On average, SION is likely to trade around $54.76 in the coming 90 days.
Sionna Therapeutics Stock Forecast 2025
Based on our predictive models, Sionna Therapeutics (SION) is expected to trade between $13.37 and $107.81 throughout 2026. This would result in an average price of $63.17, potentially offering investors a +729.00% return from current levels.
Sionna Therapeutics, Inc. Monthly Forecast 2026–2027
September 2026
According to our latest forecast models, Sionna Therapeutics, Inc. (SION) is positioned to show a strong performance in September 2026. The price is predicted to move between $13.37 and $27.57, settling at an average of $22.55. This could translate to a +195.93% gain.
October 2026
Based on current market signals, Sionna Therapeutics, Inc. is projected to trend october 2026. We forecast a trading range from $26.31 to $65.37, with a likely average price of $51.11. Investors could expect a potential return of +570.73%.
November 2026
Our predictive algorithms indicate Sionna Therapeutics, Inc. stock may see a shift in November 2026. The expected range spans $54.09–$87.40, with an average target of $70.15. This represents a positive outlook and a possible gain of +820.60%.
December 2026
Analyzing established trends, Sionna Therapeutics, Inc. looks set to move in December 2026. Projections place the stock between $81.51 and $107.81, averaging around $94.81. This suggests a +1,144.23% gain from current levels.
January 2027
Market indicators suggest Sionna Therapeutics, Inc. could experience notable changes during January 2027. Prices could fluctuate within $40.01 to $103.41, with a midpoint forecast of $53.92. The stock might deliver a +607.61% gain.
February 2027
Forecasting for February 2027, models estimate that Sionna Therapeutics, Inc. may undergo key fluctuations. If trends hold, the stock might trade between $58.09 and $83.71, averaging $73.82. This signals a positive trajectory with potential returns around +868.77%.
March 2027
According to our latest forecast models, Sionna Therapeutics, Inc. (SION) is positioned to show a strong performance in March 2027. The price is predicted to move between $57.49 and $80.19, settling at an average of $73.35. This could translate to a +862.60% gain.
April 2027
Based on current market signals, Sionna Therapeutics, Inc. is projected to trend april 2027. We forecast a trading range from $55.89 to $80.31, with a likely average price of $69.62. Investors could expect a potential return of +813.65%.
May 2027
Our predictive algorithms indicate Sionna Therapeutics, Inc. stock may see a shift in May 2027. The expected range spans $62.02–$82.19, with an average target of $72.29. This represents a positive outlook and a possible gain of +848.69%.
June 2027
Analyzing established trends, Sionna Therapeutics, Inc. looks set to move in June 2027. Projections place the stock between $0.00 and $66.82, averaging around $15.73. This suggests a +106.43% gain from current levels.
July 2027
Market indicators suggest Sionna Therapeutics, Inc. could experience notable changes during July 2027. Prices could fluctuate within $20.87 to $51.01, with a midpoint forecast of $42.03. The stock might deliver a +451.57% gain.
August 2027
Forecasting for August 2027, models estimate that Sionna Therapeutics, Inc. may undergo key fluctuations. If trends hold, the stock might trade between $0.00 and $45.73, averaging $14.24. This signals a positive trajectory with potential returns around +86.88%.
September 2027
According to our latest forecast models, Sionna Therapeutics, Inc. (SION) is positioned to show a strong performance in September 2027. The price is predicted to move between $0.00 and $20.98, settling at an average of $7.30. This could translate to a -4.20% loss.
SION's history of dividends and stock splits also plays a role in long-term investor confidence.

