How many institutions own RVMD stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own RVMD shares is 430, representing 104.33% of the company's common stock.

Who are the major shareholders selling Revolution Medicines, Inc. stock?

AMERICAN CENTURY COMPANIES INC, in the last quarter, reduced its stake in RVMD by -0.78% restricting it's holding to 451.01 thousand shares of worth nearly $21.06M. GOLDMAN SACHS GROUP INC also lessened -65.73% of the RVMD shares from its portfolio, reducing its holding to 738.03 thousand shares of worth $34.47M. CASDIN CAPITAL, LLC also shunned RVMD shares holding by -8.33% last quarter which brought its holding to 2.65 million shares worth $123.63M.

Investors who are buying RVMD stock?

As per its latest 13F filing, BARCLAYS PLC increased its stake in RVMD by 13.29% in the last quarter. The institutional holder raised its holding to 290.45 thousand shares having worth more than $13.56M. NUVEEN, LLC also added 31.06% more shares of RVMD to its portfolio, raising its holding to 337.47 thousand shares of worth $15.76M. BNP PARIBAS ARBITRAGE, SNC also increased its RVMD shares holding by 15.61% which brought its holding to 424.68 thousand shares worth $19.83M.

RVMD's major insiders: who are they?

The insider with the most stakes in RVMD is TEPPER ROBERT I , at the company. Additionally, RVMD stock is highly held by director Schroeder Thilo and See Remarks Kelsey Stephen Michael among others.

Did an insider recently sell RVMD stock?

Company executives, directors, and other insiders own 2.01% percent of Revolution Medicines, Inc.'s stock. Within the last six months, there have been 26 transaction(s) in which RVMD insiders have sold stock, totaling 268.95K shares. Insiders that have sold shares include HORN MARGARET A, ANDERS JACK, and GOLDSMITH MARK A.

Which insider recently purchased RVMD stock?

There have been 0 transaction(s) during the past 6-months in which Revolution Medicines, Inc. insiders have bought stock, totalling 0 shares

How much of RVMD does insiders own?

Around 4.51M Revolution Medicines, Inc. shares are held by insiders, which represents about 2.01% of RVMD stock.

Who is the insider with the largest stake?

RVMD , TEPPER ROBERT I holds the largest portfolio of the company's shares. RVMD shares owned by TEPPER total nearly 5.1 million.

Which institution holds the most shares in RVMD?

BARCLAYS PLC is the largest institutional owner in RVMD which holds 290.45 thousand shares worth $13.56M or 0.15% of the total RVMD shares outstanding followed by NUVEEN, LLC with ownership of 337.47 thousand shares representing 0.18% of the RVMD ownership. BNP PARIBAS ARBITRAGE, SNC is the third largest stakeholder with 424.68 thousand shares or 0.23% of the ownership worth more than $19.83M.

Is Revolution Medicines, Inc. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the RVMD is concerned, it is a stock which is optionable.

Is there a short position on RVMD's shares?

Number of RVMD shares short is 13.93M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding RVMD shares are there?

As of today, 186.93M shares of RVMD are outstanding.

Is there many float in RVMD stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, RVMD has 158.55M shares in float.

RVMD short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for RVMD is 8.22.

Revolution Medicines (RVMD) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares7.45

Short Percent Of Float7.93

Shares Outstanding186.93M

Shares Float158.55M

Shares Short13.93M

Short Ratio8.22

7.93%

Short % of Float

7.45%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

2.01% Percentage of Shares held by All Insiders

104.33% Percentage of Shares held by All Institutions

106.47% Percentage of Float held by Institutions

430

Number of Institutions Holding Shares

Institutional Ownership

About 104.33% of RVMD shares are held by financial institutions. BARCLAYS PLC is the top corporate investor, holding 290.45K shares valued at $13.56M. A 0.15% stake in Revolution Medicines, Inc. is owned by the company. NUVEEN, LLC owns 337.47K shares valued at $15.76M, which translates its holding of 0.18% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Sep 30, 2025	BARCLAYS PLC	0.15%	290.45K	13.56M	34.07K	+13.29%
Sep 30, 2025	NUVEEN, LLC	0.18%	337.47K	15.76M	79.97K	+31.06%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.23%	424.68K	19.83M	57.34K	+15.61%
Sep 30, 2025	AMERICAN CENTURY COMPANIES INC	0.24%	451.01K	21.06M	-3.56K	-0.78%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	0.39%	738.03K	34.47M	-1.42M	-65.73%
Sep 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.7%	1.31M	61.19M	299.78K	+29.62%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.67%	3.15M	146.93M	151.77K	+5.07%
Sep 30, 2025	UBS GROUP AG	0.58%	1.09M	50.85M	574.21K	+111.55%
Sep 30, 2025	SIREN, L.L.C.	0.55%	1.04M	48.74M	104.97K	+11.18%
Sep 30, 2025	CANDRIAM S.C.A.	0.46%	868.72K	40.57M	149.21K	+20.74%
Sep 30, 2025	NORTHERN TRUST CORP	0.46%	859.55K	40.14M	2.93K	+0.34%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.4%	753.87K	35.21M	177.18K	+30.72%
Sep 30, 2025	CASDIN CAPITAL, LLC	1.41%	2.65M	123.63M	-240.6K	-8.33%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.87%	1.64M	76.37M	34.7K	+2.17%
Sep 30, 2025	DAFNA CAPITAL MANAGEMENT LLC	0.35%	657.18K	30.69M	-20K	-2.95%
Sep 30, 2025	FRANKLIN RESOURCES INC	0.51%	951.49K	44.43M	699.71K	+277.91%
Sep 30, 2025	LOGOS GLOBAL MANAGEMENT LP	0.53%	1M	46.7M	1M	+100.00%
Sep 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.39%	742.4K	34.67M	345K	+86.81%
Sep 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.4%	753.2K	35.17M	552.7K	+275.66%
Sep 30, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	0.53%	997.46K	46.58M	0	0
Sep 30, 2025	CALIGAN PARTNERS LP	0.57%	1.06M	49.7M	427.41K	+67.12%
Sep 30, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	0.71%	1.34M	62.36M	4.31K	+0.32%
Sep 30, 2025	MORGAN STANLEY	0.76%	1.43M	67M	383.61K	+36.50%
Sep 30, 2025	JANE STREET GROUP, LLC	0.32%	597.46K	27.9M	-692.62K	-53.69%
Sep 30, 2025	JPMORGAN CHASE & CO	1.33%	2.5M	116.67M	-338.9K	-11.94%
Sep 30, 2025	WESTFIELD CAPITAL MANAGEMENT CO LP	1.34%	2.51M	117.4M	864.56K	+52.42%
Sep 30, 2025	AH CAPITAL MANAGEMENT, L.L.C.	1.46%	2.75M	128.36M	0	0
Sep 30, 2025	BVF INC/IL	2.11%	3.97M	185.63M	-1.01M	-20.22%
Sep 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	5.22%	9.81M	458.29M	-446.3K	-4.35%
Sep 30, 2025	JANUS HENDERSON GROUP PLC	6.04%	11.36M	530.31M	765.33K	+7.23%
Sep 30, 2025	WOODLINE PARTNERS LP	1.55%	2.92M	136.17M	311	+0.01%
Sep 30, 2025	HOLOCENE ADVISORS, LP	1.83%	3.44M	160.52M	-195.67K	-5.39%
Sep 30, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	1.94%	3.65M	170.47M	266.27K	+7.87%
Sep 30, 2025	D. E. SHAW & CO., INC.	0.43%	812.28K	37.93M	152.15K	+23.05%
Sep 30, 2025	HOOD RIVER CAPITAL MANAGEMENT LLC	0.49%	928.12K	43.34M	-197.9K	-17.57%
Sep 30, 2025	CITADEL ADVISORS LLC	0.63%	1.18M	55.11M	-297.59K	-20.14%
Sep 30, 2025	ALPHABET INC.	2.2%	4.13M	193.02M	0	0
Sep 30, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	2.54%	4.78M	223.34M	93.02K	+1.98%
Sep 30, 2025	PARADIGM BIOCAPITAL ADVISORS LP	3.31%	6.22M	290.63M	130K	+2.13%
Sep 30, 2025	NEXTECH INVEST, LTD.	4.04%	7.6M	354.97M	0	0
Sep 30, 2025	FMR LLC	5%	9.4M	439.06M	1.08M	+12.93%
Sep 30, 2025	LUNATE CAPITAL LTD	1.17%	2.2M	102.56M	0	0
Sep 30, 2025	MIC CAPITAL MANAGEMENT UK LLP	0.27%	508.57K	23.75M	0	0
Sep 30, 2025	CAPTION MANAGEMENT, LLC	0.27%	516K	24.1M	220.8K	+74.80%
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.28%	529.27K	24.72M	34.66K	+7.01%
Sep 30, 2025	TD ASSET MANAGEMENT INC	0.28%	535.6K	25.01M	28K	+5.52%
Sep 30, 2025	EVENTIDE ASSET MANAGEMENT, LLC	0.32%	595.04K	27.79M	222.81K	+59.86%
Sep 30, 2025	AMERIPRISE FINANCIAL INC	0.65%	1.22M	57.2M	-119.7K	-8.90%
Sep 30, 2025	DEKABANK DEUTSCHE GIROZENTRALE	0.03%	50K	2.28M	0	0
Sep 30, 2025	SEI INVESTMENTS CO	0.03%	51.93K	2.43M	724	+1.41%
Sep 30, 2025	Y-INTERCEPT (HONG KONG) LTD	0.03%	55.32K	2.58M	-43.58K	-44.06%
Sep 30, 2025	STATE OF NEW JERSEY COMMON PENSION FUND D	0.03%	58.31K	2.72M	5.48K	+10.37%
Sep 30, 2025	HANDELSBANKEN FONDER AB	0.03%	58.38K	2.73M	11.7K	+25.07%
Sep 30, 2025	ALLIANZ ASSET MANAGEMENT GMBH	0.04%	73.48K	3.43M	-49.07K	-40.04%
Sep 30, 2025	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0.04%	76.93K	3.59M	11.33K	+17.28%
Sep 30, 2025	TREASURER OF THE STATE OF NORTH CAROLINA	0.04%	77.92K	3.64M	-3.04K	-3.76%
Sep 30, 2025	UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH	0.04%	78.73K	3.68M	7.42K	+10.41%
Sep 30, 2025	HEALTHINVEST PARTNERS AB	0.05%	85.36K	423.18K	3.08K	+3.74%
Sep 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.05%	100K	4.67M	100K	+100.00%
Sep 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.06%	119.81K	5.59M	33.82K	+39.33%
Sep 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0.07%	124.64K	5.82M	-65.56K	-34.47%
Sep 30, 2025	TEMA ETFS LLC	0.07%	126.92K	5.93M	32.69K	+34.70%
Sep 30, 2025	NEOS INVESTMENT MANAGEMENT LLC	0.07%	126.92K	5.93M	32.69K	+34.70%
Sep 30, 2025	RHUMBLINE ADVISERS	0.08%	153.81K	7.18M	-2.78K	-1.77%
Sep 30, 2025	LEGAL & GENERAL GROUP PLC	0.08%	155.39K	7.26M	-7.44K	-4.57%
Sep 30, 2025	MARSHALL WACE, LLP	0.09%	161.1K	7.52M	133.42K	+481.97%
Sep 30, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.1%	179.83K	8.4M	26.86K	+17.55%
Sep 30, 2025	HSBC HOLDINGS PLC	0.1%	188.2K	8.78M	-43.69K	-18.84%
Sep 30, 2025	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.1%	191.33K	8.93B	158.63K	+485.19%
Sep 30, 2025	INVESCO LTD.	0.11%	200.94K	9.38M	-26.08K	-11.49%
Sep 30, 2025	CATALYST FUNDS MANAGEMENT PTY LTD	0.11%	210.17K	9.81M	164.57K	+360.90%
Sep 30, 2025	BESSEMER GROUP INC	0.13%	243.87K	11.39M	296	+0.12%
Sep 30, 2025	ENSIGN PEAK ADVISORS, INC	0.13%	248.48K	11.6M	-123.38K	-33.18%
Sep 30, 2025	VICTORY CAPITAL MANAGEMENT INC	0.13%	251.81K	11.76M	-115.28K	-31.40%
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.13%	253.1K	11.82M	9.6K	+3.94%
Sep 30, 2025	WCM INVESTMENT MANAGEMENT, LLC	0.13%	253.38K	11.67M	-4.44K	-1.72%
Sep 30, 2025	SWISS NATIONAL BANK	0.14%	270.83K	12.65M	4.4K	+1.65%
Sep 30, 2025	VESTAL POINT CAPITAL, LP	0.33%	630K	29.42M	-570K	-47.50%
Sep 30, 2025	FIRST TURN MANAGEMENT, LLC	0.34%	643.05K	30.03M	227.46K	+54.73%
Sep 30, 2025	GENERAL ATLANTIC, L.P.	1.32%	2.47M	115.56M	2.47M	+100.00%
Sep 30, 2025	DIMENSIONAL FUND ADVISORS LP	0.77%	1.44M	67.28M	444.69K	+44.64%
Sep 30, 2025	VANGUARD GROUP INC	8.32%	15.66M	731.47M	-98.6K	-0.63%
Sep 30, 2025	FARALLON CAPITAL MANAGEMENT LLC	7.77%	14.63M	683.02M	300K	+2.09%
Sep 30, 2025	BAKER BROS. ADVISORS LP	5.03%	9.46M	441.57M	90.39K	+0.97%
Sep 30, 2025	BLACKROCK, INC.	4.43%	8.33M	388.91M	-333.64K	-3.85%
Sep 30, 2025	BELLEVUE GROUP AG	2.96%	5.57M	260.3M	994.54K	+21.72%
Sep 30, 2025	STATE STREET CORP	2.79%	5.25M	245.39M	535.73K	+11.35%
Sep 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	2.06%	3.87M	180.9M	-828.26K	-17.62%
Jun 30, 2025	BOXER CAPITAL MANAGEMENT, LLC	0.42%	792.98K	29.17M	-525K	-39.83%
Jun 30, 2025	LUNATE CAPITAL LTD	1.17%	2.2M	80.8M	0	0
Jun 30, 2025	FIRST TURN MANAGEMENT, LLC	0.22%	415.59K	15.29M	75.48K	+22.19%
Jun 30, 2025	NEXTECH INVEST, LTD.	4.04%	7.6M	279.64B	0	0
Jun 30, 2025	NORGES BANK	0.9%	1.7M	62.58M	1.7M	+100.00%
Jun 30, 2025	AH CAPITAL MANAGEMENT, L.L.C.	1.46%	2.75M	101.12M	0	0
Jun 30, 2025	JPMORGAN CHASE & CO	1.51%	2.84M	104.38M	-865.68K	-23.38%
Jun 30, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.27%	500.7K	18.42M	200.5K	+66.79%
Jun 30, 2025	TD ASSET MANAGEMENT INC	0.27%	507.6K	18.67M	181.72K	+55.76%
Jun 30, 2025	UBS GROUP AG	0.27%	514.75K	18.94M	32.65K	+6.77%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0.31%	576.68K	21.22M	130.12K	+29.14%
Jun 30, 2025	CANDRIAM S.C.A.	0.38%	719.51K	26.47M	64.38K	+9.83%
Jun 30, 2025	POLAR CAPITAL HOLDINGS PLC	0.4%	751.66K	27.65M	990	+0.13%
Jun 30, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.42%	786.02K	28.92M	602.88K	+329.19%
Jun 30, 2025	HOOD RIVER CAPITAL MANAGEMENT LLC	0.6%	1.13M	41.43M	-591.03K	-34.42%
Jun 30, 2025	JANE STREET GROUP, LLC	0.69%	1.29M	47.46M	952.67K	+282.36%
Jun 30, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	0.71%	1.33M	48.97M	49.32K	+3.85%
Jun 30, 2025	AMERIPRISE FINANCIAL INC	0.71%	1.34M	49.46M	-146.2K	-9.81%
Jun 30, 2025	MILLENNIUM MANAGEMENT LLC	0.73%	1.38M	50.8M	1.22M	+783.16%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.85%	1.6M	58.89M	-329.78K	-17.08%
Jun 30, 2025	WESTFIELD CAPITAL MANAGEMENT CO LP	0.88%	1.65M	60.68M	585.36K	+55.01%
Jun 30, 2025	LOGOS GLOBAL MANAGEMENT LP	0.9%	1.7M	62.54M	100K	+6.25%
Jun 30, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	1.8%	3.38M	124.5M	66.74K	+2.01%
Jun 30, 2025	HOLOCENE ADVISORS, LP	1.93%	3.63M	133.66M	-58.79K	-1.59%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.59%	2.99M	110.16M	-1.15M	-27.73%
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	2.5%	4.7M	172.99M	-897.68K	-16.03%
Jun 30, 2025	STATE STREET CORP	2.51%	4.72M	173.61M	-1.09M	-18.71%
Jun 30, 2025	BAKER BROS. ADVISORS LP	4.98%	9.36M	344.54M	1.43M	+17.99%
Jun 30, 2025	BLACKROCK, INC.	4.6%	8.66M	318.65M	-6.03M	-41.05%
Jun 30, 2025	VESTAL POINT CAPITAL, LP	0.64%	1.2M	44.15M	1.2M	+100.00%
Jun 30, 2025	AVIDITY PARTNERS MANAGEMENT LP	0.12%	228.6K	8.41M	15.6K	+7.32%
Jun 30, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	2.49%	4.69M	172.52M	3.02M	+180.22%
Jun 30, 2025	BELLEVUE GROUP AG	2.43%	4.58M	168.47M	205K	+4.69%
Jun 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.54%	1.01M	37.24M	264.4K	+35.37%
Jun 30, 2025	SIREN, L.L.C.	0.5%	938.76K	34.54M	375K	+66.52%
Jun 30, 2025	BESSEMER GROUP INC	0.13%	243.57K	8.96M	0	0
Jun 30, 2025	HRT FINANCIAL LP	0.36%	686.43K	25.25M	662.72K	+2,795.46%
Jun 30, 2025	DAFNA CAPITAL MANAGEMENT LLC	0.36%	677.18K	24.91M	21K	+3.20%
Jun 30, 2025	D. E. SHAW & CO., INC.	0.35%	660.13K	24.29B	660.13K	+100.00%
Jun 30, 2025	CALIGAN PARTNERS LP	0.34%	636.84K	23.43M	171.84K	+36.95%
Jun 30, 2025	AMERICAN CENTURY COMPANIES INC	0.24%	454.57K	16.72M	-287.29K	-38.73%
Jun 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	5.45%	10.26M	377.46M	-1.53M	-12.96%
Jun 30, 2025	JANUS HENDERSON GROUP PLC	5.63%	10.59M	389.68M	400.66K	+3.93%
Jun 30, 2025	VANGUARD GROUP INC	8.38%	15.76M	579.87M	-850.34K	-5.12%
Jun 30, 2025	CASDIN CAPITAL, LLC	1.53%	2.89M	106.25M	-810K	-21.90%
Jun 30, 2025	WOODLINE PARTNERS LP	1.55%	2.92M	107.26M	-971.46K	-24.99%
Jun 30, 2025	FARALLON CAPITAL MANAGEMENT LLC	7.61%	14.33M	527.04M	791K	+5.84%
Jun 30, 2025	TREXQUANT INVESTMENT LP	0.13%	253.34K	9.32M	194.12K	+327.83%
Jun 30, 2025	WCM INVESTMENT MANAGEMENT, LLC	0.14%	257.81K	9.52M	11.82K	+4.80%
Jun 30, 2025	ALPHABET INC.	2.2%	4.13M	152.06M	0	0
Jun 30, 2025	BVF INC/IL	2.65%	4.98M	183.3M	0	0
Jun 30, 2025	PARADIGM BIOCAPITAL ADVISORS LP	3.24%	6.09M	224.17M	-84.82K	-1.37%
Jun 30, 2025	WEISS ASSET MANAGEMENT LP	0.16%	303.77K	11.18M	303.77K	+100.00%
Jun 30, 2025	MORGAN STANLEY	0.56%	1.05M	38.67B	-204.65K	-16.30%
Jun 30, 2025	CITADEL ADVISORS LLC	0.79%	1.48M	54.36B	1.34M	+1,010.47%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	1.14%	2.15M	79.22B	-11.1K	-0.51%
Jun 30, 2025	FMR LLC	4.42%	8.33M	306.28M	789.41K	+10.48%
Jun 30, 2025	BIOIMPACT CAPITAL LLC	0.17%	315.72K	11.62M	-1.36K	-0.43%
Jun 30, 2025	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.17%	325K	11.96M	75K	+30.00%
Jun 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.2%	367.35K	13.51B	-157.08K	-29.95%
Jun 30, 2025	ENSIGN PEAK ADVISORS, INC	0.2%	371.86K	13.68M	-55.61K	-13.01%
Jun 30, 2025	EVENTIDE ASSET MANAGEMENT, LLC	0.2%	372.23K	13.69M	0	0
Jun 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.21%	397.4K	14.62M	3.4K	+0.86%
Jun 30, 2025	CHECKPOINT CAPITAL L.P.	0.15%	280K	10.3M	-112.01K	-28.57%
Jun 30, 2025	MIC CAPITAL MANAGEMENT UK LLP	0.27%	508.57K	18.71M	0	0
Jun 30, 2025	CAPTION MANAGEMENT, LLC	0.16%	295.2K	10.86M	295.2K	+100.00%
Jun 30, 2025	RAYMOND JAMES FINANCIAL INC	0.16%	295.22K	10.86M	-8.4K	-2.77%
Jun 30, 2025		0.42%	792.98K	29.17M	-525K	-39.83%
Jun 30, 2025	NORTHERN TRUST CORP	0.46%	856.62K	31.52M	-678.13K	-44.19%
Jun 30, 2025	DIMENSIONAL FUND ADVISORS LP	0.53%	996.12K	36.65M	622.37K	+166.52%
Jun 30, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	0.53%	997.46K	36.7M	0	0
Mar 31, 2025	AH CAPITAL MANAGEMENT, L.L.C.	1.46%	2.75M	97.19M	0	0
Mar 31, 2025	HOLOCENE ADVISORS, LP	1.96%	3.69M	130.54M	695.03K	+23.19%
Mar 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.28%	524.43K	18.54M	276.1K	+111.19%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	1.15%	2.16M	76.54M	-465.65K	-17.70%
Mar 31, 2025	FINEPOINT CAPITAL LP	0.37%	691.26K	24.44M	-19K	-2.68%
Mar 31, 2025	VANGUARD GROUP INC	8.83%	16.61M	587.4M	-484.42K	-2.83%
Mar 31, 2025		0.25%	477.86K	16.9M	477.86K	+100.00%
Mar 31, 2025	BLACKROCK, INC.	7.81%	14.69M	519.52M	-27.16K	-0.18%
Mar 31, 2025	FARALLON CAPITAL MANAGEMENT LLC	7.19%	13.53M	478.59M	286K	+2.16%
Mar 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	6.27%	11.79M	416.82M	966.23K	+8.93%
Mar 31, 2025	JANUS HENDERSON GROUP PLC	5.42%	10.19M	380.57M	706.07K	+7.44%
Mar 31, 2025	BAKER BROS. ADVISORS LP	4.22%	7.94M	280.65M	0	0
Mar 31, 2025	FMR LLC	4.01%	7.54M	266.46M	793.69K	+11.77%
Mar 31, 2025	PARADIGM BIOCAPITAL ADVISORS LP	3.28%	6.18M	218.46M	-375K	-5.72%
Mar 31, 2025	STATE STREET CORP	3.09%	5.8M	205.26M	13.17K	+0.23%
Mar 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	2.98%	5.6M	198M	-266.32K	-4.54%
Mar 31, 2025	BVF INC/IL	2.65%	4.98M	176.18M	801.21K	+19.16%
Mar 31, 2025	BELLEVUE GROUP AG	2.33%	4.37M	154.68M	-12.6K	-0.29%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.2%	4.14M	146.51M	56.22K	+1.38%
Mar 31, 2025	ALPHABET INC.	2.2%	4.13M	146.15M	0	0
Mar 31, 2025	LOGOS GLOBAL MANAGEMENT LP	0.85%	1.6M	56.58M	150K	+10.34%
Mar 31, 2025	NORTHERN TRUST CORP	0.82%	1.53M	54.27M	-5.32K	-0.35%
Mar 31, 2025	AMERIPRISE FINANCIAL INC	0.79%	1.49M	52.71M	-136.19K	-8.37%
Mar 31, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	0.68%	1.28M	45.32M	68.38K	+5.64%
Mar 31, 2025	MORGAN STANLEY	0.67%	1.26M	44.4M	397.41K	+46.30%
Mar 31, 2025	WESTFIELD CAPITAL MANAGEMENT CO LP	0.57%	1.06M	37.62M	1.06M	+18,248.78%
Mar 31, 2025	UBS GROUP AG	0.26%	482.11K	17.05M	182.32K	+60.82%
Mar 31, 2025	CALIGAN PARTNERS LP	0.25%	465K	16.44M	465K	+100.00%
Mar 31, 2025	WOODLINE PARTNERS LP	2.07%	3.89M	137.45M	1.32K	+0.03%
Mar 31, 2025	JPMORGAN CHASE & CO	1.97%	3.7M	130.93M	-126.44K	-3.30%
Mar 31, 2025	CASDIN CAPITAL, LLC	1.97%	3.7M	130.76M	-1.35K	-0.04%
Mar 31, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	0.53%	997.46K	35.27M	0	0
Mar 31, 2025	POLAR CAPITAL HOLDINGS PLC	0.4%	750.67K	26.54M	0	0
Mar 31, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.4%	747.56K	26.44M	34.96K	+4.91%
Mar 31, 2025	CANDRIAM S.C.A.	0.35%	655.13K	23.17M	-1.61K	-0.24%
Mar 31, 2025	CITIGROUP INC	0.32%	609.39K	21.55M	340.93K	+127.00%
Mar 31, 2025	MIC CAPITAL MANAGEMENT UK LLP	0.27%	508.57K	17.98M	0	0
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0.24%	446.56K	15.79M	45.52K	+11.35%
Mar 31, 2025	ENSIGN PEAK ADVISORS, INC	0.23%	427.47K	15.12M	122.29K	+40.07%
Mar 31, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	1.76%	3.32M	117.3M	59K	+1.81%
Mar 31, 2025	HOOD RIVER CAPITAL MANAGEMENT LLC	0.91%	1.72M	60.71M	38.61K	+2.30%
Mar 31, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	0.89%	1.67M	59.17M	1.67M	+100.00%
Mar 31, 2025	AMERICAN CENTURY COMPANIES INC	0.39%	741.86K	26.23M	100.21K	+15.62%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	1.03%	1.93M	68.26M	-646	-0.03%
Mar 31, 2025	DAFNA CAPITAL MANAGEMENT LLC	0.35%	656.18K	23.2M	25K	+3.96%
Mar 31, 2025	BANK OF NEW YORK MELLON CORP	0.31%	582.72K	20.61M	13.71K	+2.41%
Mar 31, 2025	SIREN, L.L.C.	0.3%	563.76K	19.93M	-7.79K	-1.36%
Mar 31, 2024	STATE OF NEW JERSEY COMMON PENSION FUND D	0.08%	91.78K	2.96M	-21.62K	-19.06%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.48%	544.09K	17.54M	298.08K	+121.17%
Mar 31, 2024	CANDRIAM S.C.A.	0.52%	583.95K	18.82M	-23K	-3.79%
Mar 31, 2024	CITADEL ADVISORS LLC	0.52%	588.09K	18.95M	-315.94K	-34.95%
Mar 31, 2024	VICTORY CAPITAL MANAGEMENT INC	0.53%	600.58K	19.36M	42.21K	+7.56%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.93%	1.05M	33.91M	9.3K	+0.89%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.99%	1.12M	36.21M	70.19K	+6.66%
Mar 31, 2024	NORTHERN TRUST CORP	1.07%	1.21M	39.14M	-56.52K	-4.45%
Mar 31, 2024	ARTAL GROUP S.A.	1.17%	1.32M	42.5M	-377.3K	-22.25%
Mar 31, 2024	DIMENSIONAL FUND ADVISORS LP	1.18%	1.33M	42.91M	-464.16K	-25.85%
Mar 31, 2024	MARSHALL WACE, LLP	1.36%	1.54M	49.5M	327.01K	+27.05%
Mar 31, 2024	BALYASNY ASSET MANAGEMENT L.P.	1.46%	1.65M	53.34M	1.09M	+191.81%
Mar 31, 2024	AMERIPRISE FINANCIAL INC	1.5%	1.69M	54.61M	71.48K	+4.40%
Mar 31, 2024	PARADIGM BIOCAPITAL ADVISORS LP	2.58%	2.91M	93.95M	2.91M	+100.00%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	2.7%	3.05M	98.4M	73.91K	+2.48%
Mar 31, 2024	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	2.73%	3.09M	99.59M	0	0
Mar 31, 2024	JPMORGAN CHASE & CO	3.1%	3.51M	113.1M	-882.53K	-20.10%
Mar 31, 2024	BOXER CAPITAL, LLC	3.78%	4.28M	137.93M	0	0
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	4.25%	4.81M	155.17M	177.96K	+3.84%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.04%	45.4K	1.46M	45.4K	+100.00%
Mar 31, 2024	PROFUND ADVISORS LLC	0.04%	46.11K	1.49B	-14.99K	-24.54%
Mar 31, 2024	GUGGENHEIM CAPITAL LLC	0.04%	48.59K	1.57M	-3.06K	-5.92%
Mar 31, 2024	WEDMONT PRIVATE CAPITAL	0.04%	49.6K	1.64M	0	0
Mar 31, 2024	DEKABANK DEUTSCHE GIROZENTRALE	0.04%	50K	1.58M	0	0
Mar 31, 2024	MIRAE ASSET GLOBAL INVESTMENTS CO., LTD.	0.05%	51.06K	1.21M	-29.35K	-36.50%
Mar 31, 2024	NEW YORK STATE COMMON RETIREMENT FUND	0.05%	60.39K	1.95M	-455	-0.75%
Mar 31, 2024	HRT FINANCIAL LP	0.06%	64.05K	2.06M	64.05K	+100.00%
Mar 31, 2024	READYSTATE ASSET MANAGEMENT LP	0.06%	67.3K	2.17M	67.3K	+100.00%
Mar 31, 2024	SEVEN EIGHT CAPITAL, LP	0.06%	68.49K	2.21M	68.49K	+100.00%
Mar 31, 2024	AMERICAN INTERNATIONAL GROUP, INC.	0.06%	68.74K	2.22M	-2.75K	-3.85%
Mar 31, 2024	METLIFE INVESTMENT MANAGEMENT, LLC	0.06%	71.21K	2.3M	-4.19K	-5.56%
Mar 31, 2024	STATE OF WISCONSIN INVESTMENT BOARD	0.07%	74.11K	2.39M	-9.47K	-11.33%
Mar 31, 2024	INVESCO LTD.	0.08%	94.43K	3.04M	-34.39K	-26.69%
Mar 31, 2024	LEGAL & GENERAL GROUP PLC	0.09%	106.13K	3.42B	-2.55K	-2.35%
Mar 31, 2024	CREDIT SUISSE AG/	0.1%	112.3K	3.62M	16.54K	+17.28%
Mar 31, 2024	ALPS ADVISORS INC	0.1%	116.16K	3.74M	4.95K	+4.45%
Mar 31, 2024	NEUBERGER BERMAN GROUP LLC	0.13%	143.36K	4.62M	57.58K	+67.12%
Mar 31, 2024	QUBE RESEARCH & TECHNOLOGIES LTD	0.15%	167.48K	5.4M	141.97K	+556.40%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.18%	199.05K	6.42M	20.06K	+11.21%
Mar 31, 2024	SWISS NATIONAL BANK	0.18%	200.13K	6.45M	0	0
Mar 31, 2024	SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC	0.18%	206.51K	6.66M	206.51K	+100.00%
Mar 31, 2024	RHUMBLINE ADVISERS	0.19%	209.31K	6.75M	3.95K	+1.92%
Mar 31, 2024	BESSEMER GROUP INC	0.22%	243.44K	7.85M	0	0
Mar 31, 2024	TD ASSET MANAGEMENT INC	0.23%	254.59K	8.21B	-17.17K	-6.32%
Mar 31, 2024	CITIGROUP INC	0.25%	277.68K	8.95M	116.63K	+72.43%
Mar 31, 2024	RAFFERTY ASSET MANAGEMENT, LLC	0.25%	284.35K	9.16M	-80.74K	-22.12%
Mar 31, 2024	GREAT LAKES ADVISORS, LLC	0.26%	288.82K	9.31M	288.82K	+100.00%
Mar 31, 2024	HOLOCENE ADVISORS, LP	2.14%	2.42M	78.07M	-459.74K	-15.95%
Mar 31, 2024	AH CAPITAL MANAGEMENT, L.L.C.	2.43%	2.75M	88.58M	-2.95M	-51.76%
Mar 31, 2024	NEXTECH INVEST LTD.	5.57%	6.3M	202.94M	0	0
Mar 31, 2024	FARALLON CAPITAL MANAGEMENT LLC	6.64%	7.51M	241.98M	771.02K	+11.44%
Mar 31, 2024	BAKER BROS. ADVISORS LP	6.67%	7.55M	243.31M	2.4M	+46.63%
Mar 31, 2024	BLACKROCK INC.	10.88%	12.31M	396.69M	-646.31K	-4.99%
Mar 31, 2024	WELLINGTON MANAGEMENT GROUP LLP	13%	14.71M	474.26M	-167.36K	-1.12%
Mar 31, 2024	UBS GROUP AG	0.27%	304.98K	9.83M	-1.58K	-0.52%
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	0.29%	323.36K	10.42M	3.12K	+0.97%
Mar 31, 2024	MASS GENERAL BRIGHAM, INC	0.3%	338.19K	10.9M	338.19K	+100.00%
Mar 31, 2024	EVENTIDE ASSET MANAGEMENT, LLC	0.32%	361K	11.64M	0	0
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.33%	373.78K	12.05M	-10.89K	-2.83%
Mar 31, 2024	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.37%	420K	13.54M	220K	+110.00%
Mar 31, 2024	MIC CAPITAL MANAGEMENT UK LLP	0.45%	508.57K	16.39M	0	0
Mar 31, 2024	DAFNA CAPITAL MANAGEMENT LLC	0.45%	511.89K	16.5M	0	0
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.47%	529.41K	17.06M	-51.81K	-8.91%
Mar 31, 2024	PERCEPTIVE ADVISORS LLC	0.55%	618.89K	19.95M	-200K	-24.42%
Mar 31, 2024	AVIDITY PARTNERS MANAGEMENT LP	0.56%	635K	20.47M	575K	+958.33%
Mar 31, 2024	FINEPOINT CAPITAL LP	0.6%	677.1K	21.82M	60K	+9.72%
Mar 31, 2024	SOLEUS CAPITAL MANAGEMENT, L.P.	0.64%	728.7K	23.49M	476.7K	+189.17%
Mar 31, 2024	ROCK SPRINGS CAPITAL MANAGEMENT LP	0.82%	923.68K	29.77M	198.53K	+27.38%
Mar 31, 2024	MORGAN STANLEY	0.82%	927.07K	29.88M	-726.1K	-43.92%
Mar 31, 2024	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	0.88%	997.46K	32.15M	0	0
Mar 31, 2024	WOODLINE PARTNERS LP	3.36%	3.8M	122.38M	837.11K	+28.28%
Mar 31, 2024	JANUS HENDERSON GROUP PLC	3.46%	3.91M	126.07M	1.71M	+77.87%
Mar 31, 2024	FMR LLC	3.68%	4.17M	134.29M	2.62K	+0.06%
Mar 31, 2024	BELLEVUE GROUP AG	4.48%	5.07M	163.52M	-17.4K	-0.34%
Mar 31, 2024	ALPHABET INC.	4.69%	5.3M	170.87M	0	0
Mar 31, 2024	STATE STREET CORP	4.76%	5.39M	173.59M	-867.34K	-13.87%
Mar 31, 2024	CASDIN CAPITAL, LLC	4.96%	5.62M	181.06M	-97.18K	-1.70%
Mar 31, 2024	BVF INC/IL	5.29%	5.98M	192.77M	0	0
Mar 31, 2024	VANGUARD GROUP INC	13.04%	14.76M	475.62M	122.72K	+0.84%
Dec 31, 2023	WOODLINE PARTNERS LP	2.71%	2.96M	84.89M	-185.41K	-5.89%
Dec 31, 2023	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	2.83%	3.09M	88.62M	1.34M	+76.42%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	2.73%	2.98M	85.44M	906.05K	+43.71%
Dec 31, 2023	ARCH VENTURE MANAGEMENT, LLC	2.96%	3.23M	92.74M	3.23M	+100.00%
Dec 31, 2023	FMR LLC	3.81%	4.16M	119.43M	3.47M	+495.88%
Dec 31, 2023	BOXER CAPITAL, LLC	3.92%	4.28M	122.74M	-404.8K	-8.64%
Dec 31, 2023	JPMORGAN CHASE & CO	4.02%	4.39M	125.95M	111.71K	+2.61%
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	4.24%	4.64M	132.97M	-458.35K	-9.00%
Dec 31, 2023	BELLEVUE GROUP AG	4.66%	5.09M	146.01M	369.5K	+7.83%
Dec 31, 2023	BAKER BROS. ADVISORS LP	4.71%	5.15M	147.66M	2.46M	+91.29%
Dec 31, 2023	ALPHABET INC.	4.85%	5.3M	152.05M	5.3M	+100.00%
Dec 31, 2023	CASDIN CAPITAL, LLC	5.23%	5.71M	163.9M	3.9M	+215.73%
Dec 31, 2023	BVF INC/IL	5.48%	5.98M	171.54M	2M	+50.24%
Dec 31, 2023	STATE STREET CORP	5.72%	6.25M	179.35M	2.39M	+61.69%
Dec 31, 2023	NEXTECH INVEST LTD.	5.76%	6.3M	180.59M	1.46M	+30.11%
Dec 31, 2023	FARALLON CAPITAL MANAGEMENT LLC	6.17%	6.74M	193.21M	3.41M	+102.58%
Dec 31, 2023	BLACKROCK INC.	11.86%	12.95M	371.53M	4.08M	+46.02%
Dec 31, 2023	VANGUARD GROUP INC	13.4%	14.63M	419.71M	4.99M	+51.75%
Dec 31, 2023	WELLINGTON MANAGEMENT GROUP LLP	13.62%	14.88M	426.82M	14.88M	+100.00%
Dec 31, 2023	ALLIANCEBERNSTEIN L.P.	0.29%	320.25K	9.18M	64.2K	+25.07%
Dec 31, 2023	LOGOS GLOBAL MANAGEMENT LP	0.32%	350K	10.04M	100K	+40.00%
Dec 31, 2023	BARCLAYS PLC	0.32%	353.79K	10.15M	125.12K	+54.72%
Dec 31, 2023	EVENTIDE ASSET MANAGEMENT, LLC	0.33%	361K	10.35M	0	0
Dec 31, 2023	RAFFERTY ASSET MANAGEMENT, LLC	0.33%	365.1K	10.47M	138.15K	+60.88%
Dec 31, 2023	NUVEEN ASSET MANAGEMENT, LLC	0.35%	384.67K	11.03M	109.72K	+39.91%
Dec 31, 2023	MIC CAPITAL MANAGEMENT UK LLP	0.47%	508.57K	14.59M	508.57K	+100.00%
Dec 31, 2023	DAFNA CAPITAL MANAGEMENT LLC	0.47%	511.89K	14.68M	38.5K	+8.13%
Dec 31, 2023	VICTORY CAPITAL MANAGEMENT INC	0.51%	558.37K	16.01M	216.01K	+63.09%
Dec 31, 2023	BALYASNY ASSET MANAGEMENT L.P.	0.52%	567.11K	16.26M	-395.55K	-41.09%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.53%	581.22K	16.67M	160.85K	+38.26%
Dec 31, 2023	CANDRIAM S.C.A.	0.56%	606.95K	17.41M	45K	+8.01%
Dec 31, 2023	FINEPOINT CAPITAL LP	0.56%	617.1K	17.7M	190.1K	+44.52%
Dec 31, 2023	TANG CAPITAL MANAGEMENT LLC	0.62%	679.63K	19.49M	679.63K	+100.00%
Dec 31, 2023	ROCK SPRINGS CAPITAL MANAGEMENT LP	0.66%	725.15K	20.8M	0	0
Dec 31, 2023	PERCEPTIVE ADVISORS LLC	0.75%	818.88K	23.49M	-502.91K	-38.05%
Dec 31, 2023	CITADEL ADVISORS LLC	0.83%	904.03K	25.93M	657.57K	+266.81%
Dec 31, 2023		0.66%	725K	20.79M	725K	+100.00%
Dec 31, 2023	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	0.91%	997.46K	28.61M	0	0
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.95%	1.04M	29.91M	276.3K	+36.04%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.96%	1.05M	30.21M	425.81K	+67.86%
Dec 31, 2023	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	1.02%	1.11M	31.9M	1.11M	+100.00%
Dec 31, 2023	MARSHALL WACE, LLP	1.11%	1.21M	34.67M	1.12M	+1,304.29%
Dec 31, 2023	NORTHERN TRUST CORP	1.16%	1.27M	36.45M	337.67K	+36.19%
Dec 31, 2023	AMERIPRISE FINANCIAL INC	1.49%	1.62M	46.55M	411.17K	+33.93%
Dec 31, 2023	MORGAN STANLEY	1.51%	1.65M	47.41M	851.2K	+106.14%
Dec 31, 2023	ARTAL GROUP S.A.	1.55%	1.7M	48.64M	-833.79K	-32.96%
Dec 31, 2023	DIMENSIONAL FUND ADVISORS LP	1.64%	1.8M	51.5M	133.56K	+8.04%
Dec 31, 2023	JANUS HENDERSON GROUP PLC	2.01%	2.2M	63.09M	-41.26K	-1.84%
Dec 31, 2023	HOLOCENE ADVISORS, LP	2.64%	2.88M	82.66M	691.43K	+31.56%

Insiders

Among the RVMD insiders holding of 2.01% of the stake in company, TEPPER ROBERT I, , holds the largest shares of 5.1M. SCHROEDER THILO, director, is the second largest RVMD insider with ownership of 760.87K shares. KELSEY STEPHEN MICHAEL, See Remarks, stands third with possession of 278.6K shares of that stake.

Insiders	Designation	Shares Held
TEPPER ROBERT I		5.1M
SCHROEDER THILO	director	760.87K
KELSEY STEPHEN MICHAEL	See Remarks	278.6K
GOLDSMITH MARK A	See Remarks	232.47K
HORN MARGARET A	Chief Operating Officer	141.05K
ANDERS JACK	Chief Financial Officer	108.07K
WEI LIN	Chief Medical Officer	88.34K
KIM LORENCE H.		60.5K
WANG XIAOLIN	See Remarks	58.81K
CISLINI JEFF	General Counsel	47.88K
PATEL SUSHIL	director	19.95K
WEBER BARBARA	director	13.07K
EXTER NEIL		0

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Jan 07, 2026	HORN MARGARET A	SALE	102.90	1.7K	174.93K	141.05K
Jan 07, 2026	ANDERS JACK	SALE	98.00	10K	980K	108.07K
Dec 16, 2025	GOLDSMITH MARK A	SALE	76.82	15.39K	1.18M	232.47K
Dec 16, 2025	ANDERS JACK	SALE	77.09	3.1K	239.29K	108.07K
Dec 16, 2025	HORN MARGARET A	SALE	76.82	4.85K	372.33K	141.05K
Dec 16, 2025	KELSEY STEPHEN MICHAEL	SALE	76.82	5.45K	418.42K	278.6K
Dec 16, 2025	CISLINI JEFF	SALE	76.82	2.69K	206.48K	47.88K
Nov 25, 2025	GOLDSMITH MARK A	SALE	75.00	3K	225K	67.42K
Nov 25, 2025	ANDERS JACK	SALE	74.00	5.42K	400.93K	110.99K
Nov 18, 2025	GOLDSMITH MARK A	SALE	70.38	20K	1.41M	247.86K
Nov 18, 2025	CISLINI JEFF	SALE	70.14	13.39K	939.01K	50.43K
Nov 12, 2025	GOLDSMITH MARK A	SALE	65.07	20K	1.3M	247.86K
Nov 11, 2025	ANDERS JACK	SALE	64.00	10K	640K	110.99K
Nov 07, 2025	GOLDSMITH MARK A	SALE	60.31	30K	1.81M	347.86K
Oct 13, 2025	KELSEY STEPHEN MICHAEL	SALE	48.54	25K	1.21M	284.05K
Sep 24, 2025	CISLINI JEFF	SALE	44.26	1.8K	79.62K	50.43K
Sep 16, 2025	GOLDSMITH MARK A	SALE	45.82	13.41K	614.56K	452.31K
Sep 16, 2025	HORN MARGARET A	SALE	45.82	4.78K	218.81K	145.9K
Sep 16, 2025	ANDERS JACK	SALE	45.82	2.32K	106.31K	110.99K
Sep 16, 2025	CISLINI JEFF	SALE	45.82	1.87K	85.65K	52.22K
Sep 16, 2025	WEI LIN	SALE	45.82	2.16K	98.98K	88.34K
Sep 16, 2025	KELSEY STEPHEN MICHAEL	SALE	45.82	5.37K	245.94K	284.05K
Sep 15, 2025	KELSEY STEPHEN MICHAEL	SALE	46.93	1.32K	61.85K	289.41K
Sep 11, 2025	KELSEY STEPHEN MICHAEL	SALE	44.48	55.94K	2.49M	289.41K
Sep 03, 2025	ANDERS JACK	SALE	40.17	5.24K	210.43K	113.31K
Sep 02, 2025	ANDERS JACK	SALE	40.02	4.76K	190.56K	113.31K
Jun 20, 2025	CISLINI JEFF	SALE	39.61	1.91K	75.74K	54.09K
Jun 16, 2025	GOLDSMITH MARK A	SALE	39.83	13.5K	537.55K	428.72K
Jun 16, 2025	ANDERS JACK	SALE	39.83	2.17K	86.43K	113.31K
Jun 16, 2025	HORN MARGARET A	SALE	39.83	3.51K	139.8K	150.68K
Jun 16, 2025	WEI LIN	SALE	39.83	2.17K	86.55K	90.5K
Jun 16, 2025	KELSEY STEPHEN MICHAEL	SALE	39.83	4.29K	170.83K	289.41K
Jun 16, 2025	CISLINI JEFF	SALE	39.83	1.88K	74.8K	56.01K
Mar 20, 2025	CISLINI JEFF	SALE	38.71	2.04K	79.01K	57.72K
Mar 17, 2025	ANDERS JACK	SALE	39.04	1.86K	72.77K	115.01K
Mar 17, 2025	CISLINI JEFF	SALE	39.04	1.46K	56.92K	59.76K
Mar 17, 2025	GOLDSMITH MARK A	SALE	39.04	11.74K	458.26K	441.56K
Mar 17, 2025	KELSEY STEPHEN MICHAEL	SALE	39.04	3.29K	128.6K	293.05K
Mar 17, 2025	HORN MARGARET A	SALE	39.04	3.06K	119.39K	153.53K
Jan 21, 2025	CISLINI JEFF	SALE	40.50	2.41K	97.44K	39.22K
Dec 16, 2024	GOLDSMITH MARK A	SALE	45.40	11.71K	531.86K	325.06K
Dec 16, 2024	CISLINI JEFF	SALE	45.40	1.6K	72.6K	41.63K
Dec 16, 2024	ANDERS JACK	SALE	45.40	2.64K	119.64K	96.47K
Dec 16, 2024	HORN MARGARET A	SALE	45.40	4.33K	196.55K	127.99K
Dec 16, 2024	KELSEY STEPHEN MICHAEL	SALE	45.40	4.66K	211.72K	259.75K
Dec 05, 2024	SCHROEDER THILO	PURCHASE	46.00	760.87K	35M	760.87K
Nov 15, 2024	CISLINI JEFF	SALE	55.13	2.55K	140.81K	43.08K
Nov 13, 2024	KELSEY STEPHEN MICHAEL	SALE	59.45	2.89K	171.69K	264.41K
Nov 06, 2024	CISLINI JEFF	SALE	60.00	6K	360K	45.63K
Nov 04, 2024	GOLDSMITH MARK A	SALE	55.56	50.9K	2.83M	300.17K
Nov 01, 2024	GOLDSMITH MARK A	SALE	55.03	5K	275.13K	20.42K
Oct 31, 2024	PATEL SUSHIL	SALE	54.14	5K	270.71K	19.95K
Oct 14, 2024	KELSEY STEPHEN MICHAEL	SALE	50.08	2.61K	130.7K	264.41K
Oct 11, 2024	HORN MARGARET A	SALE	50.34	50K	2.52M	132.32K
Oct 11, 2024	CISLINI JEFF	SALE	50.17	6K	301.03K	45.63K
Oct 11, 2024	GOLDSMITH MARK A	SALE	50.36	30K	1.51M	300.17K
Oct 11, 2024	ANDERS JACK	SALE	50.30	10K	502.98K	98.93K
Oct 08, 2024	WEBER BARBARA	SALE	48.02	5.2K	249.72K	13.07K
Oct 01, 2024	GOLDSMITH MARK A	SALE	45.46	2.02K	91.91K	300.17K
Sep 16, 2024	CISLINI JEFF	SALE	44.19	1.45K	64.25K	45.63K
Sep 16, 2024	ANDERS JACK	SALE	44.19	2.24K	99.15K	98.93K
Sep 16, 2024	GOLDSMITH MARK A	SALE	44.19	11.72K	517.63K	300.17K
Sep 16, 2024	HORN MARGARET A	SALE	44.19	4.33K	191.37K	132.32K
Sep 16, 2024	KELSEY STEPHEN MICHAEL	SALE	44.19	4.67K	206.12K	264.41K
Sep 13, 2024	KELSEY STEPHEN MICHAEL	SALE	43.65	10.7K	467.05K	269.07K
Aug 13, 2024	KELSEY STEPHEN MICHAEL	SALE	42.98	16.67K	716.39K	269.07K
Aug 01, 2024	GOLDSMITH MARK A	SALE	46.48	3.22K	149.52K	311.89K
Jul 15, 2024	KELSEY STEPHEN MICHAEL	SALE	48.06	3.88K	186.42K	269.07K
Jul 12, 2024	GOLDSMITH MARK A	SALE	45.01	5K	225.06K	25.42K
Jul 09, 2024	CISLINI JEFF	SALE	40.83	2.4K	97.95K	47.09K
Jul 09, 2024	PATEL SUSHIL	SALE	44.00	2.16K	94.82K	19.95K
Jun 26, 2024	CISLINI JEFF	SALE	38.47	2K	76.94K	49.49K
Jun 25, 2024	KELSEY STEPHEN MICHAEL	SALE	39.06	16.47K	643.15K	269.07K
Jun 24, 2024	KELSEY STEPHEN MICHAEL	SALE	39.00	200	7.8K	269.07K
Jun 17, 2024	WEI LIN	SALE	37.39	5.59K	208.95K	70.85K
Jun 17, 2024	ANDERS JACK	SALE	37.39	1.89K	70.77K	101.18K
Jun 17, 2024	HORN MARGARET A	SALE	37.39	4.42K	165.06K	136.65K
Jun 17, 2024	CISLINI JEFF	SALE	37.39	1.76K	65.69K	51.49K
Jun 17, 2024	KELSEY STEPHEN MICHAEL	SALE	37.39	3.35K	125.21K	269.07K
Jun 17, 2024	GOLDSMITH MARK A	SALE	37.39	11.95K	446.77K	311.89K
Jun 03, 2024	GOLDSMITH MARK A	SALE	40.93	901	36.88K	322.32K
May 21, 2024	CISLINI JEFF	SALE	39.51	800	31.6K	52.87K
May 03, 2024	ANDERS JACK	SALE	40.03	10K	400.26K	101.96K
Apr 10, 2024	GOLDSMITH MARK A	SALE	35.34	5K	176.69K	30.42K
Apr 10, 2024	PATEL SUSHIL	SALE	37.00	2.16K	79.74K	15.7K
Mar 27, 2024	CISLINI JEFF	SALE	31.52	800	25.21K	54.37K
Mar 18, 2024	HORN MARGARET A	SALE	31.58	2.91K	92.03K	139.55K
Mar 18, 2024	ANDERS JACK	SALE	31.58	1.26K	39.83K	101.96K
Mar 18, 2024	CISLINI JEFF	SALE	31.58	1.25K	39.54K	55.87K
Mar 18, 2024	KELSEY STEPHEN MICHAEL	SALE	31.58	2.12K	67.05K	270.91K
Mar 18, 2024	GOLDSMITH MARK A	SALE	31.58	5.79K	182.8K	460.38K
Mar 12, 2024	HORN MARGARET A	SALE	34.07	7.94K	270.35K	142.47K
Mar 11, 2024	HORN MARGARET A	SALE	34.02	15.74K	535.31K	142.47K
Jan 22, 2024	CISLINI JEFF	SALE	27.00	1.5K	40.5K	36.13K
Jan 08, 2024	KELSEY STEPHEN MICHAEL	SALE	29.01	3.34K	96.81K	221.63K
Jan 02, 2024	KELSEY STEPHEN MICHAEL	SALE	29.10	13.33K	387.88K	224.97K
Dec 27, 2023	KELSEY STEPHEN MICHAEL	SALE	29.01	33.33K	967K	238.3K
Dec 18, 2023	CISLINI JEFF	SALE	25.90	1.23K	31.83K	37.28K
Dec 18, 2023	ANDERS JACK	SALE	25.90	1.78K	45.98K	76.42K
Dec 18, 2023	GOLDSMITH MARK A	SALE	25.90	8.17K	211.49K	376.17K
Dec 18, 2023	HORN MARGARET A	SALE	25.90	2.99K	77.52K	101.47K
Dec 18, 2023	KELSEY STEPHEN MICHAEL	SALE	25.90	2.09K	54.08K	271.63K
Dec 15, 2023	HORN MARGARET A	SALE	26.64	5K	133.18K	104.46K
Dec 06, 2023	HORN MARGARET A	SALE	25.00	5K	125K	104.46K
Nov 20, 2023	CISLINI JEFF	SALE	21.70	1.5K	32.54K	38.51K
Oct 16, 2023	HORN MARGARET A	SALE	34.99	400	14K	96.96K
Oct 11, 2023	KELSEY STEPHEN MICHAEL	SALE	29.05	16.67K	484.13K	273.72K
Sep 28, 2023	CISLINI JEFF	SALE	29.06	202	5.87K	40.01K
Sep 18, 2023	KELSEY STEPHEN MICHAEL	SALE	31.31	2.06K	64.5K	290.39K
Sep 18, 2023	GOLDSMITH MARK A	SALE	31.31	8.05K	252.17K	349.33K
Sep 18, 2023	CISLINI JEFF	SALE	31.31	1.21K	38.01K	42.01K
Sep 18, 2023	ANDERS JACK	SALE	31.31	1.43K	44.68K	53.67K
Sep 18, 2023	HORN MARGARET A	SALE	31.31	2.51K	78.71K	96.96K
Sep 15, 2023	HORN MARGARET A	SALE	32.08	5K	160.41K	99.47K
Sep 01, 2023	WEBER BARBARA	SALE	35.07	15K	526K	15.83K
Sep 01, 2023	GOLDSMITH MARK A	SALE	35.04	5K	175.22K	35.42K
Sep 01, 2023	ANDERS JACK	SALE	35.05	20K	701.09K	55.09K
Aug 31, 2023	HORN MARGARET A	SALE	34.05	10K	340.46K	99.47K
Aug 15, 2023	HORN MARGARET A	SALE	30.80	1.92K	58.98K	99.47K
Aug 02, 2023	KELSEY STEPHEN MICHAEL	SALE	32.40	16.67K	539.98K	292.45K
Aug 01, 2023	KELSEY STEPHEN MICHAEL	SALE	29.19	16.67K	486.5K	309.11K
Jul 31, 2023	CISLINI JEFF	SALE	26.02	1.5K	39.03K	43.23K
Jun 20, 2023	HORN MARGARET A	SALE	24.89	2.1K	52.32K	99.47K
Jun 20, 2023	ANDERS JACK	SALE	24.89	1.25K	31.09K	55.09K
Jun 20, 2023	CISLINI JEFF	SALE	25.14	1.24K	31.15K	44.73K
Jun 20, 2023	KELSEY STEPHEN MICHAEL	SALE	24.89	2.1K	52.32K	325.78K
Mar 17, 2023	KELSEY STEPHEN MICHAEL	SALE	21.78	1.23K	26.79K	326.37K
Mar 17, 2023	WANG XIAOLIN	SALE	21.78	714	15.55K	58.81K
Mar 17, 2023	ANDERS JACK	SALE	21.78	665	14.48K	55.23K
Mar 17, 2023	HORN MARGARET A	SALE	21.78	1.23K	26.79K	100.06K
Mar 10, 2023	SCHROEDER THILO	PURCHASE	20.43	93.8K	1.92M	1.55M
Mar 07, 2023	SCHROEDER THILO	PURCHASE	22.00	318.18K	7M	618.18K
Dec 19, 2022	WANG XIAOLIN	SALE	22.94	708	16.24K	30.53K
Dec 19, 2022	HORN MARGARET A	SALE	22.94	1.22K	27.99K	61.29K
Dec 19, 2022	KELSEY STEPHEN MICHAEL	SALE	22.94	1.22K	27.99K	287.6K
Dec 19, 2022	ANDERS JACK	SALE	22.94	658	15.09K	29.3K
Nov 07, 2022	HORN MARGARET A	SALE	20.15	17.77K	358.07K	0
Oct 31, 2022	HORN MARGARET A	SALE	20.41	17.77K	362.54K	17.77K
Oct 26, 2022	HORN MARGARET A	SALE	20.15	17.77K	357.97K	35.53K
Sep 19, 2022	KELSEY STEPHEN MICHAEL	SALE	19.04	1.27K	24.13K	288.82K
Sep 19, 2022	HORN MARGARET A	SALE	19.04	1.27K	24.13K	62.51K
Jul 22, 2022	SCHROEDER THILO	PURCHASE	20.00	250K	5M	1.22M
Jul 22, 2022	KIM LORENCE H.	PURCHASE	20.00	50K	1M	60.5K
Jun 17, 2022	ANDERS JACK	SALE	17.75	406	7.21K	20.41K
Jun 17, 2022	KELSEY STEPHEN MICHAEL	SALE	17.75	1.15K	20.32K	290.09K
Jun 17, 2022	HORN MARGARET A	SALE	17.75	1.15K	20.32K	63.78K
Jun 17, 2022	WANG XIAOLIN	SALE	17.75	665	11.8K	31.97K
Jun 08, 2022	TEPPER ROBERT I	SALE	20.25	419.9K	8.5M	5.1M
Jun 08, 2022	EXTER NEIL	SALE	0.00	0	-	0
Mar 25, 2022	SCHROEDER THILO	PURCHASE	24.71	725	17.91K	971.32K
Mar 22, 2022	SCHROEDER THILO	PURCHASE	24.26	49.12K	1.19M	928.59K
Mar 17, 2022	HORN MARGARET A	SALE	18.61	321	5.98K	63.99K
Mar 17, 2022	SCHROEDER THILO	PURCHASE	20.38	76.21K	1.55M	620.5K
Mar 17, 2022	WANG XIAOLIN	SALE	18.61	240	4.47K	31.7K
Mar 17, 2022	KELSEY STEPHEN MICHAEL	SALE	18.62	321	5.98K	290.29K
Mar 17, 2022	GOLDSMITH MARK A	SALE	18.61	1.02K	19.04K	185.6K
Mar 17, 2022	ANDERS JACK	SALE	18.62	159	2.96K	19.88K
Mar 10, 2022	SCHROEDER THILO	PURCHASE	20.93	3.11K	65.09K	528.18K
Mar 07, 2022	SCHROEDER THILO	PURCHASE	19.90	18.94K	376.91K	445.07K
Mar 04, 2022	SCHROEDER THILO	PURCHASE	17.69	56.3K	995.95K	238.23K
Mar 03, 2022	SCHROEDER THILO	PURCHASE	19.13	10.87K	208K	181.93K
Mar 02, 2022	SCHROEDER THILO	PURCHASE	18.94	116.29K	2.2M	116.29K
Dec 17, 2021	WANG XIAOLIN	SALE	24.41	257	6.27K	11.94K
Dec 17, 2021	HORN MARGARET A	SALE	24.41	491	11.99K	25.51K
Dec 17, 2021	ANDERS JACK	SALE	24.41	170	4.15K	8.43K
Dec 17, 2021	GOLDSMITH MARK A	SALE	24.41	1.57K	38.35K	82.62K
Dec 17, 2021	KELSEY STEPHEN MICHAEL	SALE	24.41	343	8.37K	251.82K
Sep 17, 2021	WANG XIAOLIN	SALE	30.02	250	7.51K	12.2K
Sep 17, 2021	KELSEY STEPHEN MICHAEL	SALE	30.02	335	10.06K	252.16K
Sep 17, 2021	ANDERS JACK	SALE	30.02	166	4.98K	8.19K
Sep 17, 2021	HORN MARGARET A	SALE	30.02	479	14.38K	26K
Sep 17, 2021	GOLDSMITH MARK A	SALE	30.02	1.53K	45.96K	46.47K
Feb 08, 2021	SCHROEDER THILO	PURCHASE	45.00	300K	13.5M	300K
Jul 13, 2020	SCHROEDER THILO	PURCHASE	26.00	150K	3.9M	2.67M
Feb 18, 2020	SCHROEDER THILO	PURCHASE	17.00	400K	6.8M	2.52M

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES268.95K26

NET SHARES-268.95K26

SHARES HELD4.51M26

% NET SHARES-105.96%0%

Frequently Asked Questions