How many institutions own RPTX stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own RPTX shares is 58, representing 64.93% of the company's common stock.

Who are the major shareholders selling Repare Therapeutics Inc. stock?

NIKKO ASSET MANAGEMENT AMERICAS, INC., in the last quarter, reduced its stake in RPTX by -100% restricting it's holding to 0 shares of worth nearly -. NORTHERN TRUST CORP also lessened -8.32% of the RPTX shares from its portfolio, reducing its holding to 262.2 thousand shares of worth $461.47K. CITADEL ADVISORS LLC also shunned RPTX shares holding by -25.41% last quarter which brought its holding to 699.3 thousand shares worth $1.23M.

Investors who are buying RPTX stock?

As per its latest 13F filing, SQUAREPOINT OPS LLC increased its stake in RPTX by 100% in the last quarter. The institutional holder raised its holding to 65.24 thousand shares having worth more than $114.83K. UBS GROUP AG also added 100% more shares of RPTX to its portfolio, raising its holding to 3.55 thousand shares of worth $6.25K. MORGAN STANLEY also increased its RPTX shares holding by 1,213.45% which brought its holding to 6.74 thousand shares worth $11.86K.

RPTX's major insiders: who are they?

The insider with the most stakes in RPTX is LAMPERT MARK N , at the company. Additionally, RPTX stock is highly held by 10 percent owner GADICKE ANSBERT and director Foley Todd among others.

Did an insider recently sell RPTX stock?

Company executives, directors, and other insiders own 1.25% percent of Repare Therapeutics Inc.'s stock. Within the last six months, there have been 0 transaction(s) in which RPTX insiders have sold stock, totaling 0 shares. Insiders that have sold shares include KOEHLER MARIA, SEGAL LLOYD MITCHELL, and FORTE STEVE.

Which insider recently purchased RPTX stock?

There have been 0 transaction(s) during the past 6-months in which Repare Therapeutics Inc. insiders have bought stock, totalling 0 shares

How much of RPTX does insiders own?

Around 0 Repare Therapeutics Inc. shares are held by insiders, which represents about 1.25% of RPTX stock.

Who is the insider with the largest stake?

RPTX , LAMPERT MARK N holds the largest portfolio of the company's shares. RPTX shares owned by LAMPERT total nearly 4.44 million.

Which institution holds the most shares in RPTX?

SQUAREPOINT OPS LLC is the largest institutional owner in RPTX which holds 65.24 thousand shares worth $114.83K or 0.15% of the total RPTX shares outstanding followed by SBI SECURITIES CO., LTD. with ownership of 1.26 thousand shares representing 0% of the RPTX ownership. UBS GROUP AG is the third largest stakeholder with 3.55 thousand shares or 0.01% of the ownership worth more than $6.25K.

Is Repare Therapeutics Inc. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the RPTX is concerned, it is a stock which is optionable.

Is there a short position on RPTX's shares?

Number of RPTX shares short is 685.46K. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding RPTX shares are there?

As of today, 42.96M shares of RPTX are outstanding.

Is there many float in RPTX stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, RPTX has 22.72M shares in float.

RPTX short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for RPTX is 1.07.

Repare Therapeutics (RPTX) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares1.6

Short Percent Of Float2.35

Shares Outstanding42.96M

Shares Float22.72M

Shares Short685.46K

Short Ratio1.07

2.35%

Short % of Float

1.6%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

1.25% Percentage of Shares held by All Insiders

64.93% Percentage of Shares held by All Institutions

65.75% Percentage of Float held by Institutions

Number of Institutions Holding Shares

Institutional Ownership

About 64.93% of RPTX shares are held by financial institutions. SQUAREPOINT OPS LLC is the top corporate investor, holding 65.24K shares valued at $114.83K. A 0.15% stake in Repare Therapeutics Inc. is owned by the company. SBI SECURITIES CO., LTD. owns 1.26K shares valued at $2.22K, which translates its holding of 0% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Sep 30, 2025	SQUAREPOINT OPS LLC	0.15%	65.24K	114.83K	65.24K	+100.00%
Sep 30, 2025	SBI SECURITIES CO., LTD.	0%	1.26K	2.22K	0	0
Sep 30, 2025	UBS GROUP AG	0.01%	3.55K	6.25K	3.55K	+100.00%
Sep 30, 2025	NIKKO ASSET MANAGEMENT AMERICAS, INC.	0%	0	-	-116.25K	-100.00%
Sep 30, 2025	MORGAN STANLEY	0.02%	6.74K	11.86K	6.23K	+1,213.45%
Sep 30, 2025	REDMILE GROUP, LLC	3.7%	1.59M	2.79M	0	0
Sep 30, 2025	ORBIMED ADVISORS LLC	7.74%	3.32M	5.85M	0	0
Sep 30, 2025	JONES FINANCIAL COMPANIES LLLP	0%	100	169	0	0
Sep 30, 2025	ENGINEERS GATE MANAGER LP	0.03%	11.5K	20.25K	0	0
Sep 30, 2025	HARBOURVEST PARTNERS LLC	0.03%	12.28K	21.61K	0	0
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.03%	12.86K	22.63K	2.35K	+22.31%
Sep 30, 2025	GSA CAPITAL PARTNERS LLP	0.03%	13.86K	24K	13.86K	+100.00%
Sep 30, 2025	IEQ CAPITAL, LLC	0.09%	38.38K	67.55K	0	0
Sep 30, 2025	QUINN OPPORTUNITY PARTNERS LLC	0.09%	40K	70.4K	0	0
Sep 30, 2025	NORTHERN TRUST CORP	0.61%	262.2K	461.47K	-23.81K	-8.32%
Sep 30, 2025	RANGELEY CAPITAL, LLC	1.5%	645.88K	1.14M	290.58K	+81.79%
Sep 30, 2025	CITADEL ADVISORS LLC	1.63%	699.3K	1.23M	-238.19K	-25.41%
Sep 30, 2025	SUMITOMO MITSUI TRUST HOLDINGS, INC.	0%	0	-	-116.25K	-100.00%
Sep 30, 2025	MILLENNIUM MANAGEMENT LLC	0%	0	-	-407.86K	-100.00%
Sep 30, 2025	RAYMOND JAMES FINANCIAL INC	0%	0	-	-230	-100.00%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0%	1	2	0	0
Sep 30, 2025	JPMORGAN CHASE & CO	0%	4	7	0	0
Sep 30, 2025	TWO SIGMA INVESTMENTS, LP	0.03%	10.97K	19.3K	-21.29K	-66.00%
Sep 30, 2025	NEWEDGE WEALTH, LLC	0.08%	32.96K	57.02K	0	0
Sep 30, 2025	VONTOBEL HOLDING LTD.	0.09%	40K	70.4K	0	0
Sep 30, 2025	XTX TOPCO LTD	0.11%	47.55K	83.68K	4.37K	+10.13%
Sep 30, 2025	CIBC WORLD MARKET INC.	0.02%	10.5K	18.48K	0	0
Sep 30, 2025	STIFEL FINANCIAL CORP	0.18%	77.6K	136.58K	-3K	-3.72%
Sep 30, 2025	MPM ASSET MANAGEMENT LLC	2.61%	1.12M	1.97M	0	0
Sep 30, 2025	VERSANT VENTURE MANAGEMENT, LLC	6.17%	2.65M	4.66M	0	0
Sep 30, 2025	BLUE OWL CAPITAL HOLDINGS LP	8.02%	3.44M	6.06M	0	0
Sep 30, 2025	BVF INC/IL	24.08%	10.33M	18.19M	0	0
Sep 30, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0%	0	-	-3.36K	-100.00%
Sep 30, 2025	TD WATERHOUSE CANADA INC.	0%	1.25K	2.23K	0	0
Sep 30, 2025	SIMPLEX TRADING, LLC	0%	0	-	-8.09K	-100.00%
Sep 30, 2025	STATE STREET CORP	0%	0	-	-19.1K	-100.00%
Sep 30, 2025	BARCLAYS PLC	0%	530	933	0	0
Sep 30, 2025	BIOIMPACT CAPITAL LLC	1.91%	819.92K	1.44M	0	0
Sep 30, 2025	GROUP ONE TRADING, L.P.	0%	0	-	-5.72K	-100.00%
Sep 30, 2025	STEWARD PARTNERS INVESTMENT ADVISORY, LLC	0%	11	19	0	0
Sep 30, 2025	FEDERATION DES CAISSES DESJARDINS DU QUEBEC	0%	259	456	-600	-69.85%
Sep 30, 2025	SRS CAPITAL ADVISORS, INC.	0.03%	12.5K	22K	7.5K	+150.00%
Sep 30, 2025	PRUDENTIAL FINANCIAL INC	0.03%	14.9K	26.22K	0	0
Sep 30, 2025	BLACKSTONE INC.	0.06%	25.96K	45.68K	0	0
Sep 30, 2025	TWO SIGMA ADVISERS, LP	0.06%	27.7K	48.75K	0	0
Sep 30, 2025	BANK OF MONTREAL /CAN/	0.24%	104.92K	184.66K	0	0
Sep 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.25%	108.1K	190.26K	10.9K	+11.21%
Sep 30, 2025	BLACKROCK, INC.	0.34%	146.55K	257.93K	0	0
Sep 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.47%	200K	352K	0	0
Sep 30, 2025	ACADIAN ASSET MANAGEMENT LLC	1.32%	568.3K	996K	-112.88K	-16.57%
Sep 30, 2025	LANTERN WEALTH ADVISORS, LLC	0.05%	20K	35.2K	20K	+100.00%
Sep 30, 2025	MILITIA CAPITAL PARTNERS, LP	0.28%	119.18K	209.75K	0	0
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	1.69%	724.16K	1.27M	201.3K	+38.50%
Jun 30, 2025	TD WATERHOUSE CANADA INC.	0%	1.25K	1.78K	0	0
Jun 30, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0.01%	3.36K	4.67K	3.36K	+100.00%
Jun 30, 2025	SRS CAPITAL ADVISORS, INC.	0.01%	5K	6.95K	0	0
Jun 30, 2025	GROUP ONE TRADING, L.P.	0.01%	5.72K	7.95K	-577	-9.16%
Jun 30, 2025	SIMPLEX TRADING, LLC	0.02%	8.09K	11K	-4.69K	-36.68%
Jun 30, 2025	CIBC WORLD MARKET INC.	0.02%	10.5K	14.6K	-2	-0.02%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0.02%	10.51K	14.61K	-3.23K	-23.51%
Jun 30, 2025	ENGINEERS GATE MANAGER LP	0.03%	11.5K	15.99K	11.5K	+100.00%
Jun 30, 2025	HARBOURVEST PARTNERS LLC	0.03%	12.28K	17.06K	0	0
Jun 30, 2025	PRUDENTIAL FINANCIAL INC	0.03%	14.9K	20.71K	-32.3K	-68.43%
Jun 30, 2025	STATE STREET CORP	0.04%	19.1K	26.55K	-303	-1.56%
Jun 30, 2025	BLACKSTONE INC.	0.06%	25.96K	36.08K	0	0
Jun 30, 2025	TWO SIGMA ADVISERS, LP	0.06%	27.7K	38.5K	27.7K	+100.00%
Jun 30, 2025	XTX TOPCO LTD	0.1%	43.17K	60.01K	43.17K	+100.00%
Jun 30, 2025	STIFEL FINANCIAL CORP	0.19%	80.6K	112.03K	0	0
Jun 30, 2025	SBI SECURITIES CO., LTD.	0%	1.26K	1.75K	0	0
Jun 30, 2025	RANGELEY CAPITAL, LLC	0.83%	355.29K	493.86K	355.29K	+100.00%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.23%	97.2K	135.11K	97.2K	+100.00%
Jun 30, 2025	BANK OF MONTREAL /CAN/	0.24%	104.92K	145.84K	-314	-0.30%
Jun 30, 2025	NIKKO ASSET MANAGEMENT AMERICAS, INC.	0.27%	116.25K	161.59K	0	0
Jun 30, 2025	SUMITOMO MITSUI TRUST HOLDINGS, INC.	0.27%	116.25K	161.59K	0	0
Jun 30, 2025	NORTHERN TRUST CORP	0.67%	286.01K	397.55K	-6.35K	-2.17%
Jun 30, 2025		0%	1.26K	1.75K	0	0
Jun 30, 2025	VERSANT VENTURE MANAGEMENT, LLC	6.17%	2.65M	3.68M	0	0
Jun 30, 2025	MILITIA CAPITAL PARTNERS, LP	0.28%	119.18K	165.66K	119.18K	+100.00%
Jun 30, 2025	BLACKROCK, INC.	0.34%	146.55K	203.71K	0	0
Jun 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.47%	200K	278K	0	0
Jun 30, 2025	MILLENNIUM MANAGEMENT LLC	0.95%	407.86K	566.92K	256.62K	+169.68%
Jun 30, 2025	RENAISSANCE TECHNOLOGIES LLC	1.22%	522.86K	726.77K	224.2K	+75.07%
Jun 30, 2025	ACADIAN ASSET MANAGEMENT LLC	1.59%	681.18K	942K	40.85K	+6.38%
Jun 30, 2025	REDMILE GROUP, LLC	3.7%	1.59M	2.2M	-298.22K	-15.83%
Jun 30, 2025	FMR LLC	0%	0	-	-1.6K	-100.00%
Jun 30, 2025	ARK INVESTMENT MANAGEMENT LLC	0%	0	-	-1.12M	-100.00%
Jun 30, 2025	SQUAREPOINT OPS LLC	0%	0	-	-11.89K	-100.00%
Jun 30, 2025	UBS GROUP AG	0%	0	-	-32.26K	-100.00%
Jun 30, 2025	JANE STREET GROUP, LLC	0%	0	-	-14.17K	-100.00%
Jun 30, 2025	VIRTU FINANCIAL LLC	0%	0	-	-12.22K	-100.00%
Jun 30, 2025	TWO SIGMA SECURITIES, LLC	0%	0	-	-18.99K	-100.00%
Jun 30, 2025	ROYAL BANK OF CANADA	0%	0	-	-2.4K	-100.00%
Jun 30, 2025	ORBIMED ADVISORS LLC	7.74%	3.32M	4.62M	0	0
Jun 30, 2025	BLUE OWL CAPITAL HOLDINGS LP	8.02%	3.44M	4.79M	0	0
Jun 30, 2025	BVF INC/IL	24.08%	10.33M	14.36M	0	0
Jun 30, 2025	MORGAN STANLEY	0%	513	713K	176	+52.23%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.04%	17.53K	24.37M	17.53K	+100.00%
Jun 30, 2025	BIOIMPACT CAPITAL LLC	1.91%	819.92K	1.14M	0	0
Jun 30, 2025	CITADEL ADVISORS LLC	0.04%	15.4K	21.41M	15.4K	+100.00%
Jun 30, 2025	MPM ASSET MANAGEMENT LLC	2.61%	1.12M	1.56M	0	0
Jun 30, 2025	TWO SIGMA INVESTMENTS, LP	0.08%	32.26K	44.83K	32.26K	+100.00%
Jun 30, 2025	RAYMOND JAMES FINANCIAL INC	0%	230	320	230	+100.00%
Jun 30, 2025	BARCLAYS PLC	0%	530	1K	-75	-12.40%
Jun 30, 2025	FEDERATION DES CAISSES DESJARDINS DU QUEBEC	0%	859	1.19K	0	0
Jun 30, 2025	NEWEDGE WEALTH, LLC	0.08%	32.96K	50.1K	32.96K	+100.00%
Jun 30, 2025	IEQ CAPITAL, LLC	0.09%	38.38K	53.35K	0	0
Jun 30, 2025	QUINN OPPORTUNITY PARTNERS LLC	0.09%	40K	55.6K	40K	+100.00%
Jun 30, 2025	VONTOBEL HOLDING LTD.	0.09%	40K	55.6K	0	0
Jun 30, 2025	DIMENSIONAL FUND ADVISORS LP	0%	0	-	-13.27K	-100.00%
Jun 30, 2025	VANGUARD GROUP INC	0%	0	-	-52.86K	-100.00%
Jun 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0%	1	1	0	0
Jun 30, 2025	JPMORGAN CHASE & CO	0%	4	6	0	0
Jun 30, 2025	STEWARD PARTNERS INVESTMENT ADVISORY, LLC	0%	11	15	0	0
Jun 30, 2025	JONES FINANCIAL COMPANIES LLLP	0%	100	139	0	0
Mar 31, 2025	AQUILO CAPITAL MANAGEMENT, LLC	3.04%	1.29M	1.28M	0	0
Mar 31, 2025	JANE STREET GROUP, LLC	0.03%	14.17K	13.97K	14.17K	+100.00%
Mar 31, 2025	BLACKROCK, INC.	0.34%	146.55K	144.48K	4.24K	+2.98%
Mar 31, 2025	NIKKO ASSET MANAGEMENT AMERICAS, INC.	0.27%	116.25K	115.09K	0	0
Mar 31, 2025	JONES FINANCIAL COMPANIES LLLP	0%	100	105	0	0
Mar 31, 2025	VONTOBEL HOLDING LTD.	0.09%	40K	39.44K	5K	+14.29%
Mar 31, 2025	IEQ CAPITAL, LLC	0.09%	38.38K	37.84K	0	0
Mar 31, 2025		0%	1.26K	1.24K	1K	+381.68%
Mar 31, 2025	TD WATERHOUSE CANADA INC.	0%	1.25K	1.26K	0	0
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0%	0	-	-110.91K	-100.00%
Mar 31, 2025	SUMITOMO MITSUI TRUST HOLDINGS, INC.	0.27%	116.25K	114.61K	0	0
Mar 31, 2025	BANK OF MONTREAL /CAN/	0.25%	105.23K	103.75K	-8	-0.01%
Mar 31, 2025	STIFEL FINANCIAL CORP	0.19%	80.6K	79.47K	-8.9K	-9.94%
Mar 31, 2025	JPMORGAN CHASE & CO	0%	4	4	-85.8K	-100.00%
Mar 31, 2025	CITADEL ADVISORS LLC	0%	900	887	900	+100.00%
Mar 31, 2025	FEDERATION DES CAISSES DESJARDINS DU QUEBEC	0%	859	847	-250	-22.54%
Mar 31, 2025	NORTHERN TRUST CORP	0.69%	292.36K	288.24K	292.36K	+100.00%
Mar 31, 2025	VANGUARD GROUP INC	0.12%	52.86K	52.12K	-1.41K	-2.59%
Mar 31, 2025	UBS GROUP AG	0.08%	32.26K	31.8K	16.95K	+110.78%
Mar 31, 2025	BLACKSTONE INC.	0.06%	25.96K	25.7K	0	0
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0.03%	13.74K	13.53K	1.99K	+16.94%
Mar 31, 2025	PRUDENTIAL FINANCIAL INC	0.11%	47.2K	46.53K	29.2K	+162.22%
Mar 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.09%	40.1K	39.53K	40.1K	+100.00%
Mar 31, 2025	TWO SIGMA SECURITIES, LLC	0.04%	18.99K	18.72K	18.99K	+100.00%
Mar 31, 2025	STATE STREET CORP	0.05%	19.4K	19.13K	-606	-3.03%
Mar 31, 2025	BVF INC/IL	24.26%	10.33M	10.19M	0	0
Mar 31, 2025	ARK INVESTMENT MANAGEMENT LLC	2.64%	1.12M	1.11M	-875.51K	-43.78%
Mar 31, 2025	AFFINITY ASSET ADVISORS, LLC	0.47%	200K	197.18K	100K	+100.00%
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	0.36%	151.24K	149.1K	-19.72K	-11.54%
Mar 31, 2025	DIMENSIONAL FUND ADVISORS LP	0.03%	13.27K	13.08K	0	0
Mar 31, 2025	SIMPLEX TRADING, LLC	0.03%	12.78K	12K	-5.58K	-30.38%
Mar 31, 2025	HARBOURVEST PARTNERS LLC	0.03%	12.28K	12.1K	0	0
Mar 31, 2025	VIRTU FINANCIAL LLC	0.03%	12.22K	12K	12.22K	+100.00%
Mar 31, 2025	SQUAREPOINT OPS LLC	0.03%	11.89K	11.72K	11.89K	+100.00%
Mar 31, 2025	CIBC WORLD MARKET INC.	0.02%	10.5K	10.35K	2	+0.02%
Mar 31, 2025	GROUP ONE TRADING, L.P.	0.01%	6.3K	6.21K	-287	-4.36%
Mar 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0%	1	1	0	0
Mar 31, 2025	BARCLAYS PLC	0%	605	1K	-1.81K	-74.93%
Mar 31, 2025	BLUE OWL CAPITAL HOLDINGS LP	8.09%	3.44M	3.4M	0	0
Mar 31, 2025	ORBIMED ADVISORS LLC	7.8%	3.32M	3.28M	0	0
Mar 31, 2025	REDMILE GROUP, LLC	4.42%	1.88M	1.86M	-31.7K	-1.65%
Mar 31, 2025	BIOIMPACT CAPITAL LLC	1.93%	819.92K	808.45K	-411.23K	-33.40%
Mar 31, 2025	ACADIAN ASSET MANAGEMENT LLC	1.5%	640.33K	624K	168.23K	+35.63%
Mar 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0.7%	298.66K	294.45K	-48.8K	-14.04%
Mar 31, 2025	ROYAL BANK OF CANADA	0.01%	2.4K	2K	2.4K	+100.00%
Mar 31, 2025	FMR LLC	0%	1.6K	1.58K	1.6K	+100.00%
Mar 31, 2025	SRS CAPITAL ADVISORS, INC.	0.01%	5K	4.93K	0	0
Mar 31, 2025	MORGAN STANLEY	0%	337	332	-193.18K	-99.83%
Mar 31, 2025	STEWARD PARTNERS INVESTMENT ADVISORY, LLC	0%	11	11	11	+100.00%
Mar 31, 2024	BLUE OWL CAPITAL HOLDINGS LP	7.41%	3.12M	14.71M	0	0
Mar 31, 2024	HARBOURVEST PARTNERS LLC	0.03%	12.28K	57.82K	0	0
Mar 31, 2024	JUMP FINANCIAL, LLC	0.03%	12.5K	58.88K	-27.1K	-68.44%
Mar 31, 2024	ORBIMED ADVISORS LLC	7.88%	3.32M	15.65M	0	0
Mar 31, 2024	ARTAL GROUP S.A.	1.66%	700K	3.3M	0	0
Mar 31, 2024	BVF INC/IL	24.52%	10.33M	48.67M	0	0
Mar 31, 2024	COMPAGNIE LOMBARD ODIER SCMA	0.03%	14K	65.94K	0	0
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.03%	12.5K	58.88K	-14.8K	-54.21%
Mar 31, 2024	VONTOBEL HOLDING LTD.	0.04%	15K	70.65K	0	0
Mar 31, 2024	OCCUDO QUANTITATIVE STRATEGIES LP	0.04%	15.44K	72.74K	-15.39K	-49.91%
Mar 31, 2024	JANE STREET GROUP, LLC	0.04%	16.93K	79.76K	-11.5K	-40.45%
Mar 31, 2024	ORACLE ALPHA INC.	0.05%	19.48K	91.76K	7.19K	+58.54%
Mar 31, 2024	STATE STREET CORP	0.05%	19.81K	93.28K	-2.83K	-12.49%
Mar 31, 2024	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.05%	21.08K	99K	21.08K	+100.00%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.05%	22.82K	107.48K	1.19K	+5.52%
Mar 31, 2024	VERSANT VENTURE MANAGEMENT, LLC	6.28%	2.65M	12.47M	0	0
Mar 31, 2024	LAZARD ASSET MANAGEMENT LLC	0%	0	-	-3.01K	-100.00%
Mar 31, 2024	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.06%	25.83K	121.64K	9.1K	+54.38%
Mar 31, 2024	BLACKSTONE INC.	0.06%	25.96K	122.26K	0	0
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	0.06%	26.54K	125.02K	0	0
Mar 31, 2024	SQUAREPOINT OPS LLC	0.06%	27.06K	127.44K	-27.43K	-50.34%
Mar 31, 2024	PDT PARTNERS, LLC	0.07%	30.08K	141.68K	30.08K	+100.00%
Mar 31, 2024	STIFEL FINANCIAL CORP	0.07%	30.4K	143.18K	30.4K	+100.00%
Mar 31, 2024	AMERICAN CENTURY COMPANIES INC	0.08%	32.44K	152.78K	6.11K	+23.19%
Mar 31, 2024	CUBIST SYSTEMATIC STRATEGIES, LLC	0.08%	35.42K	166.82K	8.76K	+32.86%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.09%	36.29K	170.91K	7.35K	+25.40%
Mar 31, 2024	DIMENSIONAL FUND ADVISORS LP	0.1%	40.77K	192.02K	-3.3K	-7.48%
Mar 31, 2024	CORTON CAPITAL INC.	0.11%	46.22K	217.71K	18.38K	+66.03%
Mar 31, 2024	EXCHANGE TRADED CONCEPTS, LLC	0.13%	54.59K	257.1K	41K	+301.80%
Mar 31, 2024	VANGUARD GROUP INC	0.13%	55.84K	263.01K	-6.82K	-10.88%
Mar 31, 2024	HARBOR CAPITAL ADVISORS, INC.	0.14%	60.66K	286K	12.6K	+26.23%
Mar 31, 2024	BLACKROCK INC.	0.15%	61.27K	288.56K	-1.44K	-2.29%
Mar 31, 2024	LEGAL & GENERAL GROUP PLC	0%	0	-	-706	-100.00%
Mar 31, 2024	JPMORGAN CHASE & CO	0%	4	19	0	0
Mar 31, 2024	CITIGROUP INC	0%	34	160	0	0
Mar 31, 2024	UBS GROUP AG	0%	518	2.44K	511	+7,300.00%
Mar 31, 2024	QUBE RESEARCH & TECHNOLOGIES LTD	0%	978	4.61K	-2.08K	-68.04%
Mar 31, 2024	ENTRYPOINT CAPITAL, LLC	0%	1.01K	4.73K	1.01K	+100.00%
Mar 31, 2024	WELLS FARGO & COMPANY/MN	0%	1.15K	5.41K	-32	-2.71%
Mar 31, 2024	TD WATERHOUSE CANADA INC.	0%	1.25K	5.38K	0	0
Mar 31, 2024	NEW YORK STATE COMMON RETIREMENT FUND	0%	1.32K	6K	0	0
Mar 31, 2024	NATIONAL BANK OF CANADA /FI/	0%	1.63K	5.75K	0	0
Mar 31, 2024	QUANTBOT TECHNOLOGIES LP	0%	2.05K	9.63K	-3.3K	-61.74%
Mar 31, 2024	SIMPLEX TRADING, LLC	0.01%	5.28K	24K	-5.28K	-50.00%
Mar 31, 2024	GROUP ONE TRADING, L.P.	0.02%	7.64K	35.97K	-4.04K	-34.60%
Mar 31, 2024	SRS CAPITAL ADVISORS, INC.	0.02%	10K	47.1K	0	0
Mar 31, 2024	CIBC WORLD MARKET INC.	0.02%	10.5K	49K	0	0
Mar 31, 2024	CITADEL ADVISORS LLC	0.16%	66.57K	313.55K	19.95K	+42.78%
Mar 31, 2024	TWO SIGMA INVESTMENTS, LP	0.16%	66.75K	314.41K	41.28K	+162.02%
Mar 31, 2024	OPALEYE MANAGEMENT INC.	0.16%	67.56K	318.21K	67.56K	+100.00%
Mar 31, 2024	BANK OF MONTREAL /CAN/	0.25%	105.26K	509.47K	300	+0.29%
Mar 31, 2024	D. E. SHAW & CO., INC.	0.29%	120.13K	565.83K	42.95K	+55.66%
Mar 31, 2024	GSA CAPITAL PARTNERS LLP	0.3%	126.21K	594K	-18.24K	-12.63%
Mar 31, 2024	ACADIAN ASSET MANAGEMENT LLC	0.32%	133.89K	625K	46.65K	+53.47%
Mar 31, 2024	HIGHVISTA STRATEGIES LLC	0.39%	165.17K	777.97K	0	0
Mar 31, 2024	MILLENNIUM MANAGEMENT LLC	0.4%	168.87K	795.35K	-13.23K	-7.27%
Mar 31, 2024	MORGAN STANLEY	0.68%	287.53K	1.35M	-45.73K	-13.72%
Mar 31, 2024	NIKKO ASSET MANAGEMENT AMERICAS, INC.	0.73%	308.45K	1.43M	-17.56K	-5.39%
Mar 31, 2024	SUMITOMO MITSUI TRUST HOLDINGS, INC.	0.73%	308.45K	1.45M	-17.56K	-5.39%
Mar 31, 2024	ENSIGN PEAK ADVISORS, INC	0.82%	344.33K	1.62M	0	0
Mar 31, 2024	RENAISSANCE TECHNOLOGIES LLC	0.83%	351K	1.65M	-4.83K	-1.36%
Mar 31, 2024	AQUILO CAPITAL MANAGEMENT, LLC	1.5%	633.27K	2.98M	0	0
Mar 31, 2024	BIOIMPACT CAPITAL LLC	3.89%	1.64M	7.72M	0	0
Mar 31, 2024	REDMILE GROUP, LLC	4.78%	2.02M	9.5M	-132.45K	-6.16%
Mar 31, 2024	ARK INVESTMENT MANAGEMENT LLC	6.42%	2.7M	12.73M	-117.78K	-4.17%
Mar 31, 2024	MPM ASSET MANAGEMENT LLC	5.32%	2.24M	10.56M	0	0
Mar 31, 2024	DEEP TRACK CAPITAL, LP	6.37%	2.68M	12.64M	-308.39K	-10.30%
Dec 31, 2023	COMPAGNIE LOMBARD ODIER SCMA	0.03%	14K	102.2K	0	0
Dec 31, 2023	BREVAN HOWARD CAPITAL MANAGEMENT LP	0.04%	15.69K	114.5K	15.69K	+100.00%
Dec 31, 2023	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.04%	16.73K	122.12K	1.81K	+12.13%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.05%	21.63K	157.86K	13.66K	+171.40%
Dec 31, 2023	STATE STREET CORP	0.05%	22.63K	165.22K	-31.31K	-58.04%
Dec 31, 2023	TWO SIGMA INVESTMENTS, LP	0.06%	25.48K	185.98K	25.48K	+100.00%
Dec 31, 2023	BLACKSTONE INC.	0.06%	25.96K	189.49K	0	0
Dec 31, 2023	AMERICAN CENTURY COMPANIES INC	0.06%	26.33K	192.22K	8.43K	+47.07%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	0.06%	26.54K	193.77K	0	0
Dec 31, 2023	CUBIST SYSTEMATIC STRATEGIES, LLC	0.06%	26.66K	194.61K	26.66K	+100.00%
Dec 31, 2023	HARBOR CAPITAL ADVISORS, INC.	0.11%	48.06K	350.8K	5.97K	+14.19%
Dec 31, 2023	MARSHALL WACE, LLP	0.06%	26.87K	196.12K	26.87K	+100.00%
Dec 31, 2023	CORTON CAPITAL INC.	0.07%	27.84K	203.23K	27.84K	+100.00%
Dec 31, 2023	JANE STREET GROUP, LLC	0.07%	28.44K	207.58K	28.44K	+100.00%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.07%	28.94K	211.25K	-35.41K	-55.03%
Dec 31, 2023	OCCUDO QUANTITATIVE STRATEGIES LP	0.07%	30.83K	225.05K	30.83K	+100.00%
Dec 31, 2023	JUMP FINANCIAL, LLC	0.09%	39.6K	289.1K	39.6K	+100.00%
Dec 31, 2023	DIMENSIONAL FUND ADVISORS LP	0.1%	44.07K	321.69K	-7.17K	-13.99%
Dec 31, 2023	CITADEL ADVISORS LLC	0.04%	15.5K	113.15K	-800	-4.91%
Dec 31, 2023	SQUAREPOINT OPS LLC	0.13%	54.49K	397.76K	36.31K	+199.71%
Dec 31, 2023	VANGUARD GROUP INC	0.15%	62.66K	457.41K	-12.4K	-16.52%
Dec 31, 2023	BLACKROCK INC.	0.15%	62.7K	457.72K	-269.15K	-81.11%
Dec 31, 2023	D. E. SHAW & CO., INC.	0.18%	77.18K	563.41K	77.18K	+100.00%
Dec 31, 2023	ACADIAN ASSET MANAGEMENT LLC	0.21%	87.25K	634K	5.62K	+6.88%
Dec 31, 2023	BANK OF MONTREAL /CAN/	0.25%	104.96K	816.6K	-1.17K	-1.10%
Dec 31, 2023	GSA CAPITAL PARTNERS LLP	0.34%	144.45K	1.05M	121.31K	+524.22%
Dec 31, 2023	HIGHVISTA STRATEGIES LLC	0.39%	165.17K	1.21M	0	0
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	0.43%	182.1K	1.33M	159.41K	+702.65%
Dec 31, 2023	NIKKO ASSET MANAGEMENT AMERICAS, INC.	0.77%	326.01K	2.38M	0	0
Dec 31, 2023	SUMITOMO MITSUI TRUST HOLDINGS, INC.	0.77%	326.01K	2.38M	0	0
Dec 31, 2023	MORGAN STANLEY	0.79%	333.26K	2.43M	282.94K	+562.25%
Dec 31, 2023	ENSIGN PEAK ADVISORS, INC	0.82%	344.33K	2.51M	0	0
Dec 31, 2023	RENAISSANCE TECHNOLOGIES LLC	0.85%	355.83K	2.6M	202.93K	+132.72%
Dec 31, 2023	LOGOS GLOBAL MANAGEMENT LP	1.43%	600K	4.38M	300K	+100.00%
Dec 31, 2023	AQUILO CAPITAL MANAGEMENT, LLC	1.5%	633.27K	4.62M	633.27K	+100.00%
Dec 31, 2023	ARTAL GROUP S.A.	1.66%	700K	5.11M	0	0
Dec 31, 2023	BIOIMPACT CAPITAL LLC	3.89%	1.64M	11.97M	0	0
Dec 31, 2023	REDMILE GROUP, LLC	5.1%	2.15M	15.69M	-255.95K	-10.64%
Dec 31, 2023	MPM ASSET MANAGEMENT LLC	5.33%	2.24M	16.37M	0	0
Dec 31, 2023	VERSANT VENTURE MANAGEMENT, LLC	6.29%	2.65M	19.32M	0	0
Dec 31, 2023	ARK INVESTMENT MANAGEMENT LLC	6.7%	2.82M	20.6M	200.68K	+7.66%
Dec 31, 2023	DEEP TRACK CAPITAL, LP	7.11%	2.99M	21.85M	-75K	-2.44%
Dec 31, 2023	BLUE OWL CAPITAL HOLDINGS LP	7.42%	3.12M	22.79M	3.12M	+100.00%
Dec 31, 2023	ORBIMED ADVISORS LLC	7.89%	3.32M	24.25M	0	0
Dec 31, 2023	BVF INC/IL	24.54%	10.33M	75.44M	2.04M	+24.62%
Dec 31, 2023	HARBOURVEST PARTNERS LLC	0.03%	12.28K	89.62K	0	0
Dec 31, 2023		0.03%	12.29K	89.7K	12.29K	+100.00%
Dec 31, 2023	EXCHANGE TRADED CONCEPTS, LLC	0.03%	13.59K	99.17K	3.45K	+33.97%
Dec 31, 2023	VONTOBEL HOLDING LTD.	0.04%	15K	109.5K	15K	+100.00%

Insiders

Among the RPTX insiders holding of 1.25% of the stake in company, LAMPERT MARK N, , holds the largest shares of 4.44M. GADICKE ANSBERT, 10 percent owner, is the second largest RPTX insider with ownership of 3.88M shares. FOLEY TODD, director, stands third with possession of 2.24M shares of that stake.

Insiders	Designation	Shares Held
LAMPERT MARK N		4.44M
GADICKE ANSBERT	10 percent owner	3.88M
FOLEY TODD	director	2.24M
JEREL DAVIS	director	2.09M
BVF PARTNERS L P/IL	10 percent owner	548.94K
KOEHLER MARIA	EVP, CHIEF MEDICAL OFFICER	227.81K
SEGAL LLOYD MITCHELL	PRESIDENT AND CEO	124.39K
VERSANT VENTURES V (CANADA), L.P.		111.48K
ORBIMED ADVISORS LLC	director	96.19K
BONITA DAVID P	director	96.19K
ZINDA MICHAEL	EVP, CHIEF SCIENTIFIC OFFICER	80.3K
FORTE STEVE	EVP, CHIEF FINANCIAL OFFICER	54.79K
VERSANT VANTAGE I GP-GP, LLC		48.78K
VERSANT VENTURES V, LLC	10 percent owner	44.07K
VERSANT VANTAGE I, L.P.	10 percent owner	44.07K
CIVIK THOMAS	director	7.5K

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Mar 12, 2025	KOEHLER MARIA	SALE	1.14	3.6K	4.1K	227.81K
Mar 12, 2025	SEGAL LLOYD MITCHELL	SALE	1.14	21.18K	24.14K	124.39K
Mar 12, 2025	FORTE STEVE	SALE	1.14	6.88K	7.85K	54.79K
Mar 12, 2025	ZINDA MICHAEL	SALE	1.14	5.61K	6.4K	80.3K
Apr 01, 2024	ZINDA MICHAEL	SALE	4.66	410	1.91K	71.91K
Apr 01, 2024	KOEHLER MARIA	SALE	4.66	300	1.4K	231.41K
Apr 01, 2024	SEGAL LLOYD MITCHELL	SALE	4.63	2.49K	11.53K	107.56K
Apr 01, 2024	FORTE STEVE	SALE	4.61	789	3.64K	44.78K
Mar 28, 2024	FORTE STEVE	SALE	4.62	825	3.81K	45.56K
Mar 28, 2024	SEGAL LLOYD MITCHELL	SALE	4.62	2.65K	12.24K	110.05K
Mar 28, 2024	KOEHLER MARIA	SALE	4.64	500	2.32K	231.71K
Mar 28, 2024	ZINDA MICHAEL	SALE	4.64	450	2.09K	72.32K
Mar 27, 2024	ZINDA MICHAEL	SALE	4.62	450	2.08K	72.77K
Mar 27, 2024	FORTE STEVE	SALE	4.62	825	3.81K	42.21K
Mar 27, 2024	KOEHLER MARIA	SALE	4.62	500	2.31K	232.21K
Mar 27, 2024	SEGAL LLOYD MITCHELL	SALE	4.63	2.65K	12.27K	83.87K
Mar 26, 2024	KOEHLER MARIA	SALE	4.60	500	2.3K	232.71K
Mar 26, 2024	FORTE STEVE	SALE	4.60	825	3.8K	43.04K
Mar 26, 2024	SEGAL LLOYD MITCHELL	SALE	4.64	2.65K	12.3K	86.52K
Mar 26, 2024	ZINDA MICHAEL	SALE	4.61	450	2.07K	73.22K
Mar 25, 2024	FORTE STEVE	SALE	4.79	825	3.95K	43.86K
Mar 25, 2024	ZINDA MICHAEL	SALE	4.78	450	2.15K	73.67K
Mar 25, 2024	KOEHLER MARIA	SALE	4.78	500	2.39K	233.21K
Mar 25, 2024	SEGAL LLOYD MITCHELL	SALE	4.79	2.65K	12.69K	89.17K
Nov 16, 2023	BVF PARTNERS L P/IL	PURCHASE	5.38	16.14K	86.91K	548.94K
Nov 15, 2023	BVF PARTNERS L P/IL	PURCHASE	5.00	47.71K	238.56K	532.8K
Nov 02, 2023	BVF PARTNERS L P/IL	PURCHASE	3.60	72.48K	260.92K	485.08K
Jun 08, 2023	ZINDA MICHAEL	SALE	12.02	2.87K	34.49K	60.12K
Jun 07, 2023	ZINDA MICHAEL	SALE	12.03	6.4K	77.04K	62.99K
Jun 06, 2023	ZINDA MICHAEL	SALE	12.04	1.2K	14.45K	69.39K
Dec 09, 2022	JEREL DAVIS	SALE	16.00	250K	4M	2.09M
Jun 13, 2022	LAMPERT MARK N	PURCHASE	12.73	74.67K	950.5K	4.44M
Jun 03, 2022	VERSANT VENTURES V (CANADA), L.P.	SALE	12.25	33.4K	409.15K	111.48K
Jun 03, 2022	VERSANT VANTAGE I, L.P.	SALE	12.25	13.2K	161.71K	44.07K
Jun 03, 2022	VERSANT VANTAGE I GP-GP, LLC	SALE	12.25	14.61K	179.01K	48.78K
Jun 03, 2022	VERSANT VENTURES V, LLC	SALE	12.25	13.2K	161.71K	44.07K
Jun 03, 2022	JEREL DAVIS	SALE	12.25	33.4K	409.15K	111.48K
Jun 02, 2022	LAMPERT MARK N	PURCHASE	12.29	258.8K	3.18M	3.23M
May 18, 2022	LAMPERT MARK N	PURCHASE	8.50	5.73K	48.71K	313.36K
Mar 15, 2022	ZINDA MICHAEL	SALE	11.30	533	6.02K	46.04K
Jan 19, 2022	BVF PARTNERS L P/IL	PURCHASE	14.10	7.9K	111.38K	307.63K
Nov 16, 2021	CIVIK THOMAS	PURCHASE	28.08	7.5K	210.6K	7.5K
Nov 15, 2021	ZINDA MICHAEL	SALE	27.87	3.9K	108.69K	533
Sep 07, 2021	ORBIMED ADVISORS LLC	SALE	33.93	26	882.18	96.19K
Sep 07, 2021	BONITA DAVID P	SALE	33.93	26	882.18	96.19K
Sep 03, 2021	ORBIMED ADVISORS LLC	SALE	34.00	212	7.21K	96.22K
Sep 03, 2021	BONITA DAVID P	SALE	34.00	212	7.21K	96.22K
Sep 02, 2021	BONITA DAVID P	SALE	34.24	483	16.54K	96.43K
Sep 02, 2021	ORBIMED ADVISORS LLC	SALE	34.24	483	16.54K	96.43K
Sep 01, 2021	BONITA DAVID P	SALE	33.98	382	12.98K	96.91K
Sep 01, 2021	ORBIMED ADVISORS LLC	SALE	33.98	382	12.98K	96.91K
Aug 31, 2021	BONITA DAVID P	SALE	33.94	249	8.45K	97.29K
Aug 31, 2021	ORBIMED ADVISORS LLC	SALE	33.94	249	8.45K	97.29K
Aug 30, 2021	BONITA DAVID P	SALE	33.92	197	6.68K	97.54K
Aug 30, 2021	ORBIMED ADVISORS LLC	SALE	33.92	197	6.68K	97.54K
Aug 27, 2021	BONITA DAVID P	SALE	33.94	209	7.09K	97.74K
Aug 27, 2021	ORBIMED ADVISORS LLC	SALE	33.94	209	7.09K	97.74K
Aug 26, 2021	BONITA DAVID P	SALE	34.52	126	4.35K	97.95K
Aug 26, 2021	ORBIMED ADVISORS LLC	SALE	34.52	126	4.35K	97.95K
Aug 25, 2021	BONITA DAVID P	SALE	34.34	208	7.14K	98.07K
Aug 25, 2021	ORBIMED ADVISORS LLC	SALE	34.34	208	7.14K	98.07K
Aug 24, 2021	ORBIMED ADVISORS LLC	SALE	34.07	119	4.05K	98.28K
Aug 24, 2021	BONITA DAVID P	SALE	34.07	119	4.05K	98.28K
Aug 23, 2021	BONITA DAVID P	SALE	34.06	209	7.12K	98.4K
Aug 23, 2021	ORBIMED ADVISORS LLC	SALE	34.06	209	7.12K	98.4K
Aug 18, 2021	BONITA DAVID P	SALE	33.99	2.85K	96.94K	3.26M
Aug 18, 2021	ORBIMED ADVISORS LLC	SALE	33.99	2.85K	96.94K	3.26M
Aug 17, 2021	ORBIMED ADVISORS LLC	SALE	34.12	16.89K	576.15K	3.26M
Aug 17, 2021	BONITA DAVID P	SALE	34.12	16.89K	576.15K	3.26M
Aug 16, 2021	ZINDA MICHAEL	SALE	33.97	14.3K	485.77K	21.23K
Jul 12, 2021	FOLEY TODD	SALE	33.58	25.25K	847.76K	2.24M
Jul 12, 2021	GADICKE ANSBERT	SALE	33.58	57.3K	1.92M	3.88M
Jul 09, 2021	FOLEY TODD	SALE	33.06	1.79K	59.24K	2.27M
Jul 09, 2021	GADICKE ANSBERT	SALE	33.06	4.07K	134.46K	3.94M

Frequently Asked Questions