How many institutions own PRLD stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own PRLD shares is 67, representing 62.34% of the company's common stock.

Who are the major shareholders selling Prelude Therapeutics Incorporated stock?

BANK OF AMERICA CORP /DE/, in the last quarter, reduced its stake in PRLD by -21.65% restricting it's holding to 8.85 thousand shares of worth nearly $12.74K. FMR LLC also lessened -18.52% of the PRLD shares from its portfolio, reducing its holding to 9.1 thousand shares of worth $13.10K. SUSQUEHANNA INTERNATIONAL GROUP, LLP also shunned PRLD shares holding by -100% last quarter which brought its holding to 0 shares worth -.

Investors who are buying PRLD stock?

As per its latest 13F filing, ROYAL BANK OF CANADA increased its stake in PRLD by 172.8% in the last quarter. The institutional holder raised its holding to 7.71 thousand shares having worth more than $11.00K. BARCLAYS PLC also added 1.28% more shares of PRLD to its portfolio, raising its holding to 8.71 thousand shares of worth $12.55K. PRUDENTIAL FINANCIAL INC also increased its PRLD shares holding by 100% which brought its holding to 25.84 thousand shares worth $37.21K.

PRLD's major insiders: who are they?

The insider with the most stakes in PRLD is ORBIMED ADVISORS LLC , at the company. Additionally, PRLD stock is highly held by Bonita David P and CEO Vaddi Krishna among others.

Did an insider recently sell PRLD stock?

Company executives, directors, and other insiders own 11.34% percent of Prelude Therapeutics Incorporated's stock. Within the last six months, there have been 0 transaction(s) in which PRLD insiders have sold stock, totaling 0 shares. Insiders that have sold shares include HUANG JANE, MOROSINI DEBORAH, and MAURO DAVID J.

Which insider recently purchased PRLD stock?

There have been 0 transaction(s) during the past 6-months in which Prelude Therapeutics Incorporated insiders have bought stock, totalling 0 shares

How much of PRLD does insiders own?

Around 0 Prelude Therapeutics Incorporated shares are held by insiders, which represents about 11.34% of PRLD stock.

Who is the insider with the largest stake?

PRLD , ORBIMED ADVISORS LLC holds the largest portfolio of the company's shares. PRLD shares owned by ORBIMED total nearly 10.12 million.

Which institution holds the most shares in PRLD?

ROYAL BANK OF CANADA is the largest institutional owner in PRLD which holds 7.71 thousand shares worth $11.00K or 0.01% of the total PRLD shares outstanding followed by BARCLAYS PLC with ownership of 8.71 thousand shares representing 0.01% of the PRLD ownership. BANK OF AMERICA CORP /DE/ is the third largest stakeholder with 8.85 thousand shares or 0.01% of the ownership worth more than $12.74K.

Is Prelude Therapeutics Incorporated stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the PRLD is concerned, it is a stock which is optionable.

Is there a short position on PRLD's shares?

Number of PRLD shares short is 510.20K. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding PRLD shares are there?

As of today, 43.75M shares of PRLD are outstanding.

Is there many float in PRLD stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, PRLD has 29.18M shares in float.

PRLD short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for PRLD is 4.1.

Prelude Therapeutics (PRLD) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares0.9

Short Percent Of Float6.78

Shares Outstanding43.75M

Shares Float29.18M

Shares Short510.20K

Short Ratio4.1

6.78%

Short % of Float

0.9%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

11.34% Percentage of Shares held by All Insiders

62.34% Percentage of Shares held by All Institutions

70.31% Percentage of Float held by Institutions

Number of Institutions Holding Shares

Institutional Ownership

About 62.34% of PRLD shares are held by financial institutions. ROYAL BANK OF CANADA is the top corporate investor, holding 7.71K shares valued at $11.00K. A 0.01% stake in Prelude Therapeutics Incorporated is owned by the company. BARCLAYS PLC owns 8.71K shares valued at $12.55K, which translates its holding of 0.01% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Sep 30, 2025	ROYAL BANK OF CANADA	0.01%	7.71K	11K	4.89K	+172.80%
Sep 30, 2025	BARCLAYS PLC	0.01%	8.71K	12.55K	110	+1.28%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.01%	8.85K	12.74K	-2.45K	-21.65%
Sep 30, 2025	FMR LLC	0.01%	9.1K	13.1K	-2.07K	-18.52%
Sep 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0%	0	-	-39.98K	-100.00%
Sep 30, 2025	AQR CAPITAL MANAGEMENT LLC	0.01%	10.5K	15.12K	-33.15K	-75.94%
Sep 30, 2025	HSBC HOLDINGS PLC	0.02%	13.75K	20.21K	-3.66K	-21.04%
Sep 30, 2025	PRUDENTIAL FINANCIAL INC	0.03%	25.84K	37.21K	25.84K	+100.00%
Sep 30, 2025	CERITY PARTNERS LLC	0.05%	34.33K	49.44K	-2.06K	-5.66%
Sep 30, 2025	MARSHALL WACE, LLP	0%	0	-	-41.75K	-100.00%
Sep 30, 2025	JANE STREET GROUP, LLC	0.05%	34.82K	50.14K	-56.93K	-62.05%
Sep 30, 2025	NORTHERN TRUST CORP	0.05%	36.42K	52.45K	-1.71K	-4.47%
Sep 30, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.07%	53.5K	77.04K	-35K	-39.55%
Sep 30, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.09%	69.25K	99.72K	0	0
Sep 30, 2025	GSA CAPITAL PARTNERS LLP	0.1%	75.16K	108K	3.78K	+5.30%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	0.1%	79.33K	114.23K	-69.85K	-46.82%
Sep 30, 2025	STATE STREET CORP	0.13%	97.59K	140.53K	0	0
Sep 30, 2025	TD ASSET MANAGEMENT INC	0.21%	160.65K	231.34K	0	0
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.29%	217.57K	313.37K	0	0
Sep 30, 2025	BLACKROCK, INC.	0.35%	264.97K	381.56K	-167.59K	-38.74%
Sep 30, 2025	MORGAN STANLEY	0.37%	284.2K	409.25K	-179	-0.06%
Sep 30, 2025	ACADIAN ASSET MANAGEMENT LLC	0.71%	540.57K	777K	0	0
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.72%	544K	783.36K	-37.8K	-6.50%
Sep 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.15%	876.34K	1.26M	-51.27K	-5.53%
Sep 30, 2025	VANGUARD GROUP INC	1.31%	992.85K	1.43M	60.28K	+6.46%
Sep 30, 2025	MILLENNIUM MANAGEMENT LLC	1.51%	1.15M	1.65M	898.62K	+361.73%
Sep 30, 2025	BAKER BROS. ADVISORS LP	13.32%	10.12M	14.58M	0	0
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0%	52	75	0	0
Sep 30, 2025	EVERSOURCE WEALTH ADVISORS, LLC	0%	89	128	-59	-39.86%
Sep 30, 2025	GROUP ONE TRADING, L.P.	0%	500	720	0	0
Sep 30, 2025	PNC FINANCIAL SERVICES GROUP, INC.	0%	1.17K	1.69K	-9	-0.76%
Sep 30, 2025	CWM, LLC	0%	1.22K	2K	-2.8K	-69.63%
Sep 30, 2025	NISA INVESTMENT ADVISORS, LLC	0%	1.63K	2.35K	0	0
Sep 30, 2025	SBI SECURITIES CO., LTD.	0%	2.74K	3.95K	0	0
Sep 30, 2025	JPMORGAN CHASE & CO	0.01%	3.88K	5.59K	1.93K	+99.03%
Sep 30, 2025	ORBIMED ADVISORS LLC	14.36%	10.91M	15.71M	0	0
Sep 30, 2025	Y-INTERCEPT (HONG KONG) LTD	0%	0	-	-47.79K	-100.00%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0%	0	-	-297	-100.00%
Sep 30, 2025	SRS CAPITAL ADVISORS, INC.	0%	15	22	15	+100.00%
Sep 30, 2025	OPTIVER HOLDING B.V.	0%	20	29	20	+100.00%
Sep 30, 2025	XTX TOPCO LTD	0.02%	15.58K	22.43K	-27K	-63.41%
Sep 30, 2025	SHAY CAPITAL LLC	0.13%	100K	144K	25K	+33.33%
Sep 30, 2025	TWO SIGMA INVESTMENTS, LP	0.2%	152.23K	219.22K	-2.74K	-1.77%
Sep 30, 2025	TWO SIGMA ADVISERS, LP	0.29%	222.7K	320.69K	-2.3K	-1.02%
Sep 30, 2025	UBS GROUP AG	0.01%	4.17K	6.01K	-100.03K	-96.00%
Sep 30, 2025	TRUE WEALTH DESIGN, LLC	0%	0	-	-13	-100.00%
Sep 30, 2025	HRT FINANCIAL LP	0.02%	16.9K	24K	16.9K	+100.00%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0%	0	-	-80.85K	-100.00%
Sep 30, 2025	CITIGROUP INC	0.01%	5.98K	8.6K	1.26K	+26.64%
Sep 30, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0.01%	6.93K	9.98K	-9.87K	-58.77%
Sep 30, 2025	CANTOR FITZGERALD, L. P.	0%	0	-	-211.86K	-100.00%
Sep 30, 2025	IFP ADVISORS, INC	0%	18	26	-16	-47.06%
Jun 30, 2025	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0%	0	-	-955	-100.00%
Jun 30, 2025	AMERITAS INVESTMENT PARTNERS, INC.	0%	0	-	-819	-100.00%
Jun 30, 2025	FMR LLC	0.01%	11.17K	9.04K	-9.07K	-44.82%
Jun 30, 2025	DEUTSCHE BANK AG\	0%	0	-	-80.72K	-100.00%
Jun 30, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0.02%	16.8K	13.6K	3.21K	+23.65%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0.01%	11.29K	9.14K	-4.15K	-26.89%
Jun 30, 2025	SBI SECURITIES CO., LTD.	0%	2.74K	2.22K	0	0
Jun 30, 2025	CITADEL ADVISORS LLC	0.04%	33.63K	27.22M	33.59K	+98,797.06%
Jun 30, 2025	AQR CAPITAL MANAGEMENT LLC	0.06%	43.65K	35.33M	9.82K	+29.05%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.2%	149.18K	120.75M	-6.04K	-3.89%
Jun 30, 2025	MORGAN STANLEY	0.37%	284.38K	230.18M	-18.4K	-6.08%
Jun 30, 2025	ACADIAN ASSET MANAGEMENT LLC	0.71%	540.57K	436K	11.24K	+2.12%
Jun 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.77%	581.8K	470.91K	-74.9K	-11.41%
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.22%	927.61K	743K	-48.54K	-4.97%
Jun 30, 2025	VANGUARD GROUP INC	1.23%	932.57K	754.45K	-76.63K	-7.59%
Jun 30, 2025	BAKER BROS. ADVISORS LP	13.32%	10.12M	8.19M	0	0
Jun 30, 2025	ORBIMED ADVISORS LLC	14.36%	10.91M	8.83M	0	0
Jun 30, 2025	HSBC HOLDINGS PLC	0.02%	17.41K	13.93K	-3.22K	-15.60%
Jun 30, 2025	CERITY PARTNERS LLC	0.05%	36.39K	29.46K	1.83K	+5.29%
Jun 30, 2025	NORTHERN TRUST CORP	0.05%	38.13K	30.86K	-78.78K	-67.39%
Jun 30, 2025	SHAY CAPITAL LLC	0.1%	75K	60.71K	75K	+100.00%
Jun 30, 2025	JPMORGAN CHASE & CO	0%	1.95K	1.58K	-21.83K	-91.80%
Jun 30, 2025	ROYAL BANK OF CANADA	0%	2.83K	2K	-517	-15.46%
Jun 30, 2025	CWM, LLC	0.01%	4.01K	3K	668	+19.96%
Jun 30, 2025		0%	2.74K	2.22K	0	0
Jun 30, 2025	CITIGROUP INC	0.01%	4.72K	3.82K	-4.58K	-49.27%
Jun 30, 2025	BARCLAYS PLC	0.01%	8.6K	7K	-14.54K	-62.83%
Jun 30, 2025	Y-INTERCEPT (HONG KONG) LTD	0.06%	47.79K	38.68K	47.79K	+100.00%
Jun 30, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.09%	69.25K	56.05K	0	0
Jun 30, 2025	GSA CAPITAL PARTNERS LLP	0.09%	71.38K	58K	71.38K	+100.00%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.11%	80.85K	65.44K	-33.21K	-29.11%
Jun 30, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.12%	88.5K	71.63K	0	0
Jun 30, 2025	JANE STREET GROUP, LLC	0.12%	91.75K	74.27K	91.75K	+100.00%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.05%	39.98K	32.36K	-37.89K	-48.66%
Jun 30, 2025	MARSHALL WACE, LLP	0.05%	41.75K	33.82K	41.75K	+100.00%
Jun 30, 2025	XTX TOPCO LTD	0.06%	42.57K	34.46K	17.87K	+72.36%
Jun 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0%	52	42	-19.62K	-99.74%
Jun 30, 2025	EVERSOURCE WEALTH ADVISORS, LLC	0%	148	120	139	+1,544.44%
Jun 30, 2025	STATE STREET CORP	0.13%	97.59K	78.99K	-188.45K	-65.88%
Jun 30, 2025	UBS GROUP AG	0.14%	104.2K	84.3K	8.05K	+8.37%
Jun 30, 2025	TWO SIGMA INVESTMENTS, LP	0.2%	154.98K	125.44K	-28.69K	-15.62%
Jun 30, 2025	TD ASSET MANAGEMENT INC	0.21%	160.65K	130.03K	0	0
Jun 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0%	0	-	-3.62K	-100.00%
Jun 30, 2025	LEGAL & GENERAL GROUP PLC	0%	0	-	-962	-100.00%
Jun 30, 2025	TRUE WEALTH DESIGN, LLC	0%	13	11	3	+30.00%
Jun 30, 2025	IFP ADVISORS, INC	0%	34	28	34	+100.00%
Jun 30, 2025	WELLS FARGO & COMPANY/MN	0%	297	240	-7.62K	-96.25%
Jun 30, 2025	GROUP ONE TRADING, L.P.	0%	500	405	0	0
Jun 30, 2025	PNC FINANCIAL SERVICES GROUP, INC.	0%	1.18K	956	-12	-1.01%
Jun 30, 2025	CANTOR FITZGERALD, L. P.	0.28%	211.86K	171.48K	211.86K	+100.00%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.29%	217.57K	176.14K	-187.39K	-46.27%
Jun 30, 2025	TWO SIGMA ADVISERS, LP	0.3%	225K	182.12K	-35.4K	-13.59%
Jun 30, 2025	MILLENNIUM MANAGEMENT LLC	0.33%	248.42K	201.07K	101.65K	+69.26%
Jun 30, 2025	BLACKROCK, INC.	0.57%	432.56K	350.11K	-615.17K	-58.71%
Jun 30, 2025	NISA INVESTMENT ADVISORS, LLC	0%	1.63K	1.32K	1.23K	+308.50%
Mar 31, 2025	ROYAL BANK OF CANADA	0%	3.34K	2K	-377	-10.13%
Mar 31, 2025	MORGAN STANLEY	0.4%	302.78K	232.54K	-62.38K	-17.08%
Mar 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.28%	976.15K	750K	-53.05K	-5.15%
Mar 31, 2025	ORBIMED ADVISORS LLC	14.36%	10.91M	8.38M	0	0
Mar 31, 2025	FMR LLC	0.03%	20.24K	15.54K	11.74K	+138.04%
Mar 31, 2025	ACADIAN ASSET MANAGEMENT LLC	0.7%	529.33K	405K	43.95K	+9.05%
Mar 31, 2025	JPMORGAN CHASE & CO	0.03%	23.78K	18.26K	-37.37K	-61.11%
Mar 31, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0%	3.62K	3K	0	0
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	0.19%	146.77K	112.72K	-315.79K	-68.27%
Mar 31, 2025	STATE STREET CORP	0.38%	286.05K	219.68K	-7.35K	-2.51%
Mar 31, 2025	TWO SIGMA ADVISERS, LP	0.34%	260.4K	199.99K	-39.6K	-13.20%
Mar 31, 2025	MIRAE ASSET GLOBAL ETFS HOLDINGS LTD.	0.01%	7.89K	6.06K	312	+4.12%
Mar 31, 2025	COREBRIDGE FINANCIAL, INC.	0.01%	6.46K	4.96K	-96	-1.46%
Mar 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0.86%	656.7K	504.35K	22.2K	+3.50%
Mar 31, 2025	TWO SIGMA INVESTMENTS, LP	0.24%	183.67K	141.06K	-48.17K	-20.78%
Mar 31, 2025	TD ASSET MANAGEMENT INC	0.21%	160.65K	123.38K	0	0
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.2%	155.22K	119.21K	6.89K	+4.64%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.15%	114.05K	87.59K	-3.15K	-2.69%
Mar 31, 2025	UBS GROUP AG	0.13%	96.16K	73.85K	28.77K	+42.69%
Mar 31, 2025	SG AMERICAS SECURITIES, LLC	0.02%	17.25K	13K	17.25K	+100.00%
Mar 31, 2025	MILITIA CAPITAL PARTNERS, LP	0.01%	4.3K	3.3K	0	0
Mar 31, 2025	CWM, LLC	0%	3.35K	3K	1.45K	+76.20%
Mar 31, 2025	PNC FINANCIAL SERVICES GROUP, INC.	0%	1.19K	915	1.13K	+1,762.50%
Mar 31, 2025	LEGAL & GENERAL GROUP PLC	0%	962	739	0	0
Mar 31, 2025	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0%	955	733	0	0
Mar 31, 2025	BAKER BROS. ADVISORS LP	13.32%	10.12M	7.78M	0	0
Mar 31, 2025	BLACKROCK, INC.	1.38%	1.05M	804.65K	-22.05K	-2.06%
Mar 31, 2025	DEUTSCHE BANK AG\	0.11%	80.72K	62.16K	-43.18K	-34.85%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.53%	404.96K	311.05K	2.62K	+0.65%
Mar 31, 2025	NORTHERN TRUST CORP	0.15%	116.91K	89.78K	33.52K	+40.20%
Mar 31, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.12%	88.5K	67.97K	-22.5K	-20.27%
Mar 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.1%	77.87K	59.8K	5.07K	+6.97%
Mar 31, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.09%	69.25K	53.19K	-793	-1.13%
Mar 31, 2025	CERITY PARTNERS LLC	0.05%	34.57K	26.55K	1.69K	+5.13%
Mar 31, 2025	AQR CAPITAL MANAGEMENT LLC	0.04%	33.82K	25.98K	21.33K	+170.74%
Mar 31, 2025	BANK OF NEW YORK MELLON CORP	0.04%	28.61K	21.98K	0	0
Mar 31, 2025	XTX TOPCO LTD	0.03%	24.7K	18.97K	-13.64K	-35.57%
Mar 31, 2025	CITADEL ADVISORS LLC	0.03%	23.9K	18.36K	17.5K	+273.44%
Mar 31, 2025	VANGUARD GROUP INC	1.33%	1.01M	775.07K	-1.19K	-0.12%
Mar 31, 2025	SIMPLEX TRADING, LLC	0.06%	41.85K	32K	23.03K	+122.42%
Mar 31, 2025	BARCLAYS PLC	0.03%	23.15K	18K	-6.63K	-22.26%
Mar 31, 2025	HSBC HOLDINGS PLC	0.03%	20.63K	17.54K	-10	-0.05%
Mar 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.03%	19.67K	15.11K	-904	-4.39%
Mar 31, 2025	RHUMBLINE ADVISERS	0.02%	15.5K	11.89K	-151.33K	-90.71%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0.02%	15.45K	11.86K	-5.21K	-25.22%
Mar 31, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0.02%	13.59K	10.43K	3.21K	+30.94%
Mar 31, 2025	CITIGROUP INC	0.01%	9.3K	7.14K	-915	-8.96%
Mar 31, 2025	WELLS FARGO & COMPANY/MN	0.01%	7.91K	6.08K	175	+2.26%
Mar 31, 2025		0%	2.74K	2.11K	0	0
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.07%	40.07K	189.92K	-10.53K	-20.81%
Mar 31, 2024	STATE OF WISCONSIN INVESTMENT BOARD	0.03%	19.6K	92.9K	-5.2K	-20.97%
Mar 31, 2024	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.03%	20.07K	95.11K	20.07K	+100.00%
Mar 31, 2024	NEW YORK STATE COMMON RETIREMENT FUND	0.03%	20.12K	95K	0	0
Mar 31, 2024	BARCLAYS PLC	0.03%	20.39K	97K	-10.14K	-33.21%
Mar 31, 2024	RHUMBLINE ADVISERS	0.04%	21.17K	100.32K	763	+3.74%
Mar 31, 2024	ACADIAN ASSET MANAGEMENT LLC	0.04%	22.11K	104K	6.62K	+42.69%
Mar 31, 2024	HSBC HOLDINGS PLC	0.04%	24.91K	118.05K	1.7K	+7.30%
Mar 31, 2024	KENNEDY CAPITAL MANAGEMENT LLC	0.04%	25.04K	118.67K	25.04K	+100.00%
Mar 31, 2024	CITADEL ADVISORS LLC	0.05%	29.8K	141.23K	-65.54K	-68.75%
Mar 31, 2024	PALE FIRE CAPITAL SE	0.05%	31.48K	149.22K	-32.1K	-50.49%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.05%	32.26K	152.93K	-5.23K	-13.94%
Mar 31, 2024	CERITY PARTNERS LLC	0.05%	32.5K	154.05K	32.5K	+100.00%
Mar 31, 2024	TWO SIGMA INVESTMENTS, LP	0.1%	60.6K	287.23K	2.31K	+3.97%
Mar 31, 2024	EXCHANGE TRADED CONCEPTS, LLC	0.11%	63.89K	302.82K	19.8K	+44.91%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.11%	67.43K	319.6K	-2.04K	-2.93%
Mar 31, 2024	TWO SIGMA ADVISERS, LP	0.12%	70.2K	332.75K	8.4K	+13.59%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.12%	72.26K	342.52K	2.1K	+2.99%
Mar 31, 2024	MILLENNIUM MANAGEMENT LLC	0.17%	101.85K	482.77K	4.88K	+5.04%
Mar 31, 2024	NORTHERN TRUST CORP	0.2%	122.15K	578.98K	8.05K	+7.06%
Mar 31, 2024	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.2%	123.6K	585.86K	-25.15K	-16.91%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.21%	127.37K	603.73K	2.67K	+2.14%
Mar 31, 2024	TD ASSET MANAGEMENT INC	0.27%	160.65K	761.49K	0	0
Mar 31, 2024	RENAISSANCE TECHNOLOGIES LLC	0.41%	244.8K	1.16M	28.4K	+13.12%
Mar 31, 2024	MORGAN STANLEY	0.49%	296.21K	1.4M	-2.59K	-0.87%
Mar 31, 2024	SIO CAPITAL MANAGEMENT, LLC	0.53%	320.39K	1.52M	0	0
Mar 31, 2024	MASSACHUSETTS FINANCIAL SERVICES CO /MA/	0.84%	508.15K	2.41M	-2.6K	-0.51%
Mar 31, 2024	VANGUARD GROUP INC	1.69%	1.02M	4.82M	10.14K	+1.01%
Mar 31, 2024	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	6.85%	4.13M	19.59M	0	0
Mar 31, 2024	BAKER BROS. ADVISORS LP	16.77%	10.12M	47.99M	0	0
Mar 31, 2024	AMUNDI	0.03%	15.13K	52.05K	0	0
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	0.6%	361.63K	1.71M	12.27K	+3.51%
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	1.56%	941.97K	4.47M	-100.77K	-9.66%
Mar 31, 2024	BOXER CAPITAL, LLC	4.26%	2.57M	12.17M	0	0
Mar 31, 2024	SG AMERICAS SECURITIES, LLC	0%	0	-	-13.1K	-100.00%
Mar 31, 2024	NELSON, VAN DENBURG & CAMPBELL WEALTH MANAGEMENT GROUP, LLC	0%	1	4	1	+100.00%
Mar 31, 2024	HIGHMARK WEALTH MANAGEMENT LLC	0%	50	237	0	0
Mar 31, 2024	AMALGAMATED BANK	0%	334	2K	-530	-61.34%
Mar 31, 2024	AMERITAS INVESTMENT PARTNERS, INC.	0%	819	3.88M	0	0
Mar 31, 2024	LEGAL & GENERAL GROUP PLC	0%	962	4.56M	0	0
Mar 31, 2024	BLACKROCK INC.	1.82%	1.1M	5.2M	1.89K	+0.17%
Mar 31, 2024	STATE STREET CORP	0.35%	211.44K	1M	-793	-0.37%
Mar 31, 2024	ORBIMED ADVISORS LLC	18.07%	10.91M	51.71M	0	0
Mar 31, 2024	CITIGROUP INC	0%	2.81K	13.32K	682	+32.06%
Mar 31, 2024	TOWER RESEARCH CAPITAL LLC (TRC)	0.01%	3.35K	15.86K	-645	-16.16%
Mar 31, 2024	WELLS FARGO & COMPANY/MN	0.01%	5.27K	25K	675	+14.68%
Mar 31, 2024	JPMORGAN CHASE & CO	0.01%	6.25K	29.61K	-3.13K	-33.40%
Mar 31, 2024	AMERICAN INTERNATIONAL GROUP, INC.	0.01%	7.33K	34.76K	-64	-0.87%
Mar 31, 2024	FMR LLC	0.02%	11.55K	54.75K	-253.14K	-95.64%
Mar 31, 2024	PRELUDE CAPITAL MANAGEMENT, LLC	0.02%	13.85K	65.63K	-500	-3.49%
Mar 31, 2024	DIMENSIONAL FUND ADVISORS LP	0.02%	14.31K	67.81K	0	0
Mar 31, 2024	UBS GROUP AG	0.03%	15.66K	74.21K	-4.22K	-21.22%
Mar 31, 2024	WALLEYE CAPITAL LLC	0.03%	16.38K	77.64K	16.38K	+100.00%
Mar 31, 2024	JANE STREET GROUP, LLC	0.03%	16.39K	77.68K	-16.59K	-50.30%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.03%	16.8K	79.62K	0	0
Mar 31, 2024	ZACKS INVESTMENT MANAGEMENT	0.03%	18.46K	87.48K	18.46K	+100.00%
Dec 31, 2023	STATE OF WISCONSIN INVESTMENT BOARD	0%	24.8K	105.9K	-36.8K	-59.74%
Dec 31, 2023	SQUAREPOINT OPS LLC	0%	29.42K	125.62K	-59.38K	-66.87%
Dec 31, 2023	BARCLAYS PLC	0%	30.53K	131K	17.21K	+129.24%
Dec 31, 2023	JANE STREET GROUP, LLC	0%	32.98K	140.81K	32.98K	+100.00%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0%	37.49K	160.08K	-15.16K	-28.79%
Dec 31, 2023	EXCHANGE TRADED CONCEPTS, LLC	0%	44.09K	188.25K	11.18K	+33.97%
Dec 31, 2023	TWO SIGMA INVESTMENTS, LP	0%	58.28K	248.87K	45.47K	+354.88%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0%	50.6K	216.06K	17.72K	+53.88%
Dec 31, 2023	AMERICAN INTERNATIONAL GROUP, INC.	0%	7.4K	31.59K	295	+4.15%
Dec 31, 2023	ROYAL BANK OF CANADA	0%	9.04K	39K	3.98K	+78.55%
Dec 31, 2023	JPMORGAN CHASE & CO	0%	9.38K	40.05K	-7.97K	-45.95%
Dec 31, 2023	SG AMERICAS SECURITIES, LLC	0%	13.1K	56K	13.1K	+100.00%
Dec 31, 2023	VIRTU FINANCIAL LLC	0%	13.61K	58K	13.61K	+100.00%
Dec 31, 2023	DIMENSIONAL FUND ADVISORS LP	0%	14.31K	60.92K	3.12K	+27.86%
Dec 31, 2023	AMUNDI	0%	15.13K	61.43K	15.13K	+100.00%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0%	69.47K	296.62K	1.78K	+2.63%
Dec 31, 2023	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0%	70.17K	299.61K	0	0
Dec 31, 2023	CITADEL ADVISORS LLC	0%	95.33K	407.06K	-204.77K	-68.23%
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	0%	96.97K	414.05K	33.1K	+51.82%
Dec 31, 2023	NORTHERN TRUST CORP	0%	114.1K	487.19K	-1.42K	-1.23%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0%	124.7K	532.47K	1.67K	+1.36%
Dec 31, 2023	JACOBS LEVY EQUITY MANAGEMENT, INC	0%	131.31K	560.68K	-12.65K	-8.79%
Dec 31, 2023	PRELUDE CAPITAL MANAGEMENT, LLC	0%	14.35K	61.26K	14.35K	+100.00%
Dec 31, 2023	ACADIAN ASSET MANAGEMENT LLC	0%	15.5K	65K	8.47K	+120.63%
Dec 31, 2023	NUVEEN ASSET MANAGEMENT, LLC	0%	16.8K	71.72K	2.99K	+21.68%
Dec 31, 2023	HSBC HOLDINGS PLC	0%	23.21K	93.77K	12	+0.05%
Dec 31, 2023	NEW YORK STATE COMMON RETIREMENT FUND	0%	20.12K	86K	-27	-0.13%
Dec 31, 2023	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0%	148.75K	635.16K	111.8K	+302.58%
Dec 31, 2023	RHUMBLINE ADVISERS	0%	20.4K	87.11K	-13.41K	-39.66%
Dec 31, 2023	TD ASSET MANAGEMENT INC	0%	160.65K	685.98K	0	0
Dec 31, 2023	STATE STREET CORP	0%	212.23K	906.24K	25.03K	+13.37%
Dec 31, 2023	RENAISSANCE TECHNOLOGIES LLC	0%	216.4K	924K	77.03K	+55.27%
Dec 31, 2023	FMR LLC	0%	264.69K	1.13M	-4.87M	-94.84%
Dec 31, 2023	UBS GROUP AG	0%	19.87K	84.86K	12.47K	+168.26%
Dec 31, 2023	MORGAN STANLEY	0%	298.8K	1.28M	54.33K	+22.22%
Dec 31, 2023	SIO CAPITAL MANAGEMENT, LLC	0%	320.39K	1.37M	-29.61K	-8.46%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	0%	349.37K	1.49M	18.27K	+5.52%
Dec 31, 2023	MASSACHUSETTS FINANCIAL SERVICES CO /MA/	0%	510.75K	2.18M	470	+0.09%
Dec 31, 2023	VANGUARD GROUP INC	0%	1.01M	4.3M	33.25K	+3.42%
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	0%	1.04M	4.45M	-24.12K	-2.26%
Dec 31, 2023	BLACKROCK INC.	0%	1.1M	4.68M	27.16K	+2.54%
Dec 31, 2023	BOXER CAPITAL, LLC	0%	2.57M	10.97M	73.27K	+2.94%
Dec 31, 2023	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	0.01%	4.13M	17.65M	4.13M	+100.00%
Dec 31, 2023	BAKER BROS. ADVISORS LP	0.02%	10.12M	43.23M	0	0
Dec 31, 2023	ORBIMED ADVISORS LLC	0.02%	10.91M	46.58M	0	0
Dec 31, 2023	TWO SIGMA ADVISERS, LP	0%	61.8K	263.89K	30.7K	+98.71%
Dec 31, 2023	PALE FIRE CAPITAL SE	0%	63.58K	271.49K	32.8K	+106.56%
Dec 31, 2023	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0%	2.45K	10.46K	-691	-22.01%
Dec 31, 2023	TOWER RESEARCH CAPITAL LLC (TRC)	0%	3.99K	17.05K	492	+14.06%
Dec 31, 2023	WELLS FARGO & COMPANY/MN	0%	4.6K	19.64K	963	+26.49%

Insiders

Among the PRLD insiders holding of 11.34% of the stake in company, ORBIMED ADVISORS LLC, , holds the largest shares of 10.12M. BONITA DAVID P, , is the second largest PRLD insider with ownership of 10.12M shares. VADDI KRISHNA, CEO, stands third with possession of 2M shares of that stake.

Insiders	Designation	Shares Held
ORBIMED ADVISORS LLC		10.12M
BONITA DAVID P		10.12M
VADDI KRISHNA	CEO	2M
BAKER BROS. ADVISORS LP		509.48K
COMBS ANDREW	Chief Chemistry Officer	480.12K
SCHERLE PEGGY	Chief Scientific Officer	172.92K
FRIEDMAN PAUL A	director	152.58K
CHARDONNET LAURENT	Chief Financial Officer	42.17K
LIM BRYANT DAVID	CLO, Interim CFO, Corp Sec.	27.4K
HUANG JANE	President, CMO	24.22K
DIER MARDI	director	10K
PIERCE CHRISTOPHER	EVP and Chief of Business Oper	3.75K
MOROSINI DEBORAH	EVP, Chief of Clinical Affairs	444
PIPER BRIAN	Chief Financial Officer	0
MAURO DAVID J	Chief Medical Officer	0

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Mar 25, 2025	VADDI KRISHNA	PURCHASE	0.69	675K	467.44K	2M
Mar 25, 2025	COMBS ANDREW	PURCHASE	0.69	100K	69.25K	480.12K
Mar 21, 2025	VADDI KRISHNA	PURCHASE	0.73	15K	10.96K	1.32M
Mar 20, 2025	VADDI KRISHNA	PURCHASE	0.73	5.42K	3.95K	1.31M
Mar 17, 2025	VADDI KRISHNA	PURCHASE	0.75	9.11K	6.83K	1.3M
Mar 14, 2025	VADDI KRISHNA	PURCHASE	0.75	30K	22.63K	1.29M
Mar 13, 2025	VADDI KRISHNA	PURCHASE	0.72	50K	35.82K	1.26M
Mar 12, 2025	VADDI KRISHNA	PURCHASE	0.71	47.5K	33.74K	1.21M
Dec 31, 2024	VADDI KRISHNA	PURCHASE	1.21	5K	6.04K	142.55K
Dec 30, 2024	VADDI KRISHNA	PURCHASE	1.20	10K	12K	137.55K
Dec 23, 2024	COMBS ANDREW	PURCHASE	1.37	60K	82K	377.62K
Dec 20, 2024	COMBS ANDREW	PURCHASE	1.15	3.08K	3.54K	317.62K
Dec 19, 2024	VADDI KRISHNA	PURCHASE	0.89	6.89K	6.12K	127.55K
Dec 19, 2024	LIM BRYANT DAVID	PURCHASE	0.91	25K	22.64K	27.4K
Dec 18, 2024	VADDI KRISHNA	PURCHASE	0.93	100K	93.21K	1.17M
May 25, 2023	VADDI KRISHNA	PURCHASE	5.31	900	4.78K	1.07M
May 24, 2023	LIM BRYANT DAVID	PURCHASE	5.39	2.4K	12.94K	2.4K
May 24, 2023	VADDI KRISHNA	PURCHASE	5.01	1K	5.01K	1.07M
May 23, 2023	VADDI KRISHNA	PURCHASE	5.63	11.86K	66.75K	1.07M
May 23, 2023	CHARDONNET LAURENT	PURCHASE	5.50	5K	27.5K	42.17K
May 22, 2023	ORBIMED ADVISORS LLC	PURCHASE	5.75	869.57K	5M	10.12M
May 22, 2023	BONITA DAVID P	PURCHASE	5.75	869.57K	5M	10.12M
Apr 06, 2023	HUANG JANE	SALE	6.12	13.28K	81.27K	24.22K
Dec 20, 2022	VADDI KRISHNA	PURCHASE	5.13	19.19K	98.45K	120.67K
Dec 08, 2022	CHARDONNET LAURENT	PURCHASE	4.76	10K	47.6K	35.87K
Jun 01, 2022	CHARDONNET LAURENT	PURCHASE	4.23	10K	42.3K	24.5K
Dec 15, 2021	MOROSINI DEBORAH	SALE	13.00	28.75K	373.76K	444
Dec 14, 2021	COMBS ANDREW	PURCHASE	11.60	4K	46.4K	268.38K
Dec 13, 2021	COMBS ANDREW	PURCHASE	12.12	4K	48.48K	264.38K
Nov 16, 2021	MOROSINI DEBORAH	SALE	16.43	400	6.57K	444
Oct 05, 2021	MAURO DAVID J	SALE	32.06	1.29K	41.33K	0
Sep 07, 2021	MAURO DAVID J	SALE	37.79	4.64K	175.33K	0
Sep 02, 2021	PIERCE CHRISTOPHER	SALE	42.50	6.93K	294.51K	3.75K
Aug 27, 2021	SCHERLE PEGGY	SALE	37.08	607	22.51K	172.92K
Aug 26, 2021	SCHERLE PEGGY	SALE	35.19	1.7K	59.82K	172.92K
Aug 25, 2021	PIPER BRIAN	SALE	34.33	2.34K	80.47K	0
Aug 13, 2021	SCHERLE PEGGY	SALE	35.07	2.29K	80.16K	172.92K
Aug 05, 2021	MAURO DAVID J	SALE	32.63	100	3.26K	0
Jul 27, 2021	SCHERLE PEGGY	SALE	36.09	680	24.54K	172.92K
Jul 06, 2021	MAURO DAVID J	SALE	28.84	300	8.65K	0
Jun 07, 2021	MAURO DAVID J	SALE	32.73	12.7K	415.66K	0
May 25, 2021	PIPER BRIAN	SALE	36.09	399	14.4K	0
May 07, 2021	SCHERLE PEGGY	SALE	41.85	200	8.37K	172.92K
May 05, 2021	MAURO DAVID J	SALE	41.07	1.11K	45.54K	0
Apr 29, 2021	MOROSINI DEBORAH	SALE	40.29	3.22K	129.85K	444
Apr 29, 2021	PIERCE CHRISTOPHER	SALE	40.29	3.3K	132.76K	3.75K
Apr 27, 2021	MAURO DAVID J	SALE	36.11	1.71K	61.79K	0
Apr 19, 2021	MAURO DAVID J	SALE	31.27	4K	125.08K	0
Apr 08, 2021	PIERCE CHRISTOPHER	SALE	40.00	200	8K	3.75K
Apr 08, 2021	MOROSINI DEBORAH	SALE	40.00	100	4K	444
Apr 08, 2021	MAURO DAVID J	SALE	39.56	3.55K	140.39K	0
Apr 08, 2021	SCHERLE PEGGY	SALE	39.57	1.67K	66.04K	172.92K
Apr 07, 2021	MOROSINI DEBORAH	SALE	40.04	1K	40.04K	444
Apr 07, 2021	MAURO DAVID J	SALE	39.69	7.08K	281.12K	0
Apr 07, 2021	SCHERLE PEGGY	SALE	40.30	200	8.06K	172.92K
Apr 07, 2021	PIERCE CHRISTOPHER	SALE	40.08	828	33.19K	3.75K
Jan 11, 2021	BAKER BROS. ADVISORS LP	PURCHASE	0.00	12.44K	-	509.48K
Jan 11, 2021	ORBIMED ADVISORS LLC	PURCHASE	0.00	41.7K	-	5.6M
Jan 11, 2021	BONITA DAVID P	PURCHASE	0.00	41.7K	-	5.6M
Sep 29, 2020	COMBS ANDREW	PURCHASE	19.00	1K	19K	260.38K
Sep 29, 2020	DIER MARDI	PURCHASE	19.00	10K	190K	10K
Sep 29, 2020	BAKER BROS. ADVISORS LP	PURCHASE	19.00	104.63K	1.99M	870.87K
Sep 25, 2020	BONITA DAVID P	PURCHASE	19.00	526.3K	10M	526.3K
Sep 25, 2020	ORBIMED ADVISORS LLC	PURCHASE	19.00	526.3K	10M	526.3K
Aug 21, 2020	BONITA DAVID P	PURCHASE	0.00	1.03M	-	1.03M
Aug 21, 2020	BAKER BROS. ADVISORS LP	PURCHASE	0.00	75.87K	-	75.87K
Aug 21, 2020	ORBIMED ADVISORS LLC	PURCHASE	0.00	1.03M	-	1.03M
Mar 27, 2020	FRIEDMAN PAUL A	PURCHASE	0.00	76.29K	-	152.58K
Mar 27, 2020	BONITA DAVID P	PURCHASE	0.00	3.68M	-	7.36M
Mar 27, 2020	ORBIMED ADVISORS LLC	PURCHASE	0.00	3.68M	-	7.36M
Mar 27, 2020	BAKER BROS. ADVISORS LP	PURCHASE	0.00	308.79K	-	308.79K

Frequently Asked Questions