How many institutions own PHVS stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own PHVS shares is 146, representing 85.23% of the company's common stock.

Who are the major shareholders selling Pharvaris N.V. stock?

BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC, in the last quarter, reduced its stake in PHVS by -4.52% restricting it's holding to 2.68 million shares of worth nearly $75.58M. DAIWA SECURITIES GROUP INC. also lessened -100% of the PHVS shares from its portfolio, reducing its holding to 0 shares of worth -. BNP PARIBAS ARBITRAGE, SNC also shunned PHVS shares holding by -97.65% last quarter which brought its holding to 1.39 thousand shares worth $39.24K.

Investors who are buying PHVS stock?

As per its latest 13F filing, SATURN V CAPITAL MANAGEMENT LLC increased its stake in PHVS by 5.38% in the last quarter. The institutional holder raised its holding to 1.2 million shares having worth more than $33.94M. WELLINGTON MANAGEMENT GROUP LLP also added 11.18% more shares of PHVS to its portfolio, raising its holding to 2.12 million shares of worth $59.86M. BARE FINANCIAL SERVICES, INC also increased its PHVS shares holding by 100% which brought its holding to 6 shares worth $170.00.

PHVS's major insiders: who are they?

The insider with the most stakes in PHVS is Schikan Johannes Gerardus Christiaan Petrus , director at the company. Additionally, PHVS stock is highly held by Chief Executive Officer Modig Berndt and CFO / CLO Nassif David W. among others.

Did an insider recently sell PHVS stock?

Company executives, directors, and other insiders own 6.14% percent of Pharvaris N.V.'s stock. Within the last six months, there have been 26 transaction(s) in which PHVS insiders have sold stock, totaling 127.84K shares. Insiders that have sold shares include MODIG BERNDT, NIJDAM ANNA, and MONGES VIVIANE.

Which insider recently purchased PHVS stock?

There have been 0 transaction(s) during the past 6-months in which Pharvaris N.V. insiders have bought stock, totalling 0 shares

How much of PHVS does insiders own?

Around 3M Pharvaris N.V. shares are held by insiders, which represents about 6.14% of PHVS stock.

Who is the insider with the largest stake?

PHVS director, Schikan Johannes Gerardus Christiaan Petrus holds the largest portfolio of the company's shares. PHVS shares owned by Schikan total nearly 355.17 thousand.

Which institution holds the most shares in PHVS?

SATURN V CAPITAL MANAGEMENT LLC is the largest institutional owner in PHVS which holds 1.2 million shares worth $33.94M or 2.03% of the total PHVS shares outstanding followed by WELLINGTON MANAGEMENT GROUP LLP with ownership of 2.12 million shares representing 3.58% of the PHVS ownership. BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC is the third largest stakeholder with 2.68 million shares or 4.52% of the ownership worth more than $75.58M.

Is Pharvaris N.V. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the PHVS is concerned, it is a stock which is optionable.

Is there a short position on PHVS's shares?

Number of PHVS shares short is 404.97K. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding PHVS shares are there?

As of today, 64.30M shares of PHVS are outstanding.

Is there many float in PHVS stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, PHVS has 37.11M shares in float.

PHVS short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for PHVS is 3.54.

Pharvaris NV (PHVS) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares0.63

Short Percent Of Float0.76

Shares Outstanding64.30M

Shares Float37.11M

Shares Short404.97K

Short Ratio3.54

0.76%

Short % of Float

0.63%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

6.14% Percentage of Shares held by All Insiders

85.23% Percentage of Shares held by All Institutions

90.81% Percentage of Float held by Institutions

146

Number of Institutions Holding Shares

Institutional Ownership

About 85.23% of PHVS shares are held by financial institutions. SATURN V CAPITAL MANAGEMENT LLC is the top corporate investor, holding 1.2M shares valued at $33.94M. A 2.03% stake in Pharvaris N.V. is owned by the company. WELLINGTON MANAGEMENT GROUP LLP owns 2.12M shares valued at $59.86M, which translates its holding of 3.58% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Mar 31, 2026	SATURN V CAPITAL MANAGEMENT LLC	2.03%	1.2M	33.94M	61.37K	+5.38%
Mar 31, 2026	WELLINGTON MANAGEMENT GROUP LLP	3.58%	2.12M	59.86M	213.11K	+11.18%
Mar 31, 2026	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	4.52%	2.68M	75.58M	-126.57K	-4.52%
Mar 31, 2026	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	5.28%	3.13M	88.31M	0	0
Mar 31, 2026	VIKING GLOBAL INVESTORS LP	6.18%	3.65M	103.21M	0	0
Mar 31, 2026	DAIWA SECURITIES GROUP INC.	0%	0	-	-213	-100.00%
Mar 31, 2026	SBI SECURITIES CO., LTD.	0%	1	28	0	0
Mar 31, 2026	BARE FINANCIAL SERVICES, INC	0%	6	170	6	+100.00%
Mar 31, 2026	CAITONG INTERNATIONAL ASSET MANAGEMENT CO., LTD	0%	18	508	12	+200.00%
Mar 31, 2026	CENTERPOINT ADVISORS, LLC	0%	100	3K	0	0
Mar 31, 2026	WELLS FARGO & COMPANY/MN	0%	450	12.71K	0	0
Mar 31, 2026	BNP PARIBAS ARBITRAGE, SNC	0%	1.39K	39.24K	-57.65K	-97.65%
Mar 31, 2026	GF FUND MANAGEMENT CO. LTD.	0%	1.44K	40.65K	181	+14.39%
Mar 31, 2026	SIMPLEX TRADING, LLC	0%	2.17K	61.39M	2.17K	+100.00%
Mar 31, 2026	QUANTBOT TECHNOLOGIES LP	0%	2.39K	67.55K	-1.87K	-43.87%
Mar 31, 2026	CITIGROUP INC	0%	2.44K	68.99K	655	+36.65%
Mar 31, 2026	MIRAE ASSET GLOBAL INVESTMENTS CO., LTD.	0.01%	3.34K	94.38K	228	+7.32%
Mar 31, 2026	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	0.01%	5.72K	161.7K	214	+3.88%
Mar 31, 2026	KLP KAPITALFORVALTNING AS	0.01%	5.8K	163.85K	0	0
Mar 31, 2026	VANGUARD INVESTMENTS AUSTRALIA, LTD.	0.01%	6.09K	172.01K	6.09K	+100.00%
Mar 31, 2026	PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO	0.01%	7.57K	213.82K	0	0
Mar 31, 2026	PERSISTENT ASSET PARTNERS LTD	0.01%	7.9K	223.29K	7.9K	+100.00%
Mar 31, 2026	TEACHER RETIREMENT SYSTEM OF TEXAS	0.01%	8.18K	230.97K	-735	-8.25%
Mar 31, 2026	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0.01%	8.24K	232.75K	0	0
Mar 31, 2026	VIRTUS INVESTMENT ADVISERS, INC.	0.02%	11.29K	318.83K	275	+2.50%
Mar 31, 2026	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.02%	11.37K	321.12K	929	+8.90%
Mar 31, 2026	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.02%	13.47K	380.53K	13.47K	+100.00%
Mar 31, 2026	VANGUARD ASSET MANAGEMENT, LTD	0.03%	15.06K	425.45K	15.06K	+100.00%
Mar 31, 2026	NUVEEN, LLC	0.03%	17.01K	480.45K	0	0
Mar 31, 2026	JUMP FINANCIAL, LLC	0.03%	19.5K	550.88K	-6.8K	-25.86%
Mar 31, 2026	JPMORGAN CHASE & CO	0.03%	20.01K	545.94K	-1.94K	-8.83%
Mar 31, 2026	PALUMBO WEALTH MANAGEMENT LLC	0.03%	20.61K	582.18K	426	+2.11%
Mar 31, 2026	LEGAL & GENERAL GROUP PLC	0.05%	26.78K	756.42K	4.11K	+18.13%
Mar 31, 2026	HRT FINANCIAL LP	0.05%	27.62K	780K	12.86K	+87.10%
Mar 31, 2026	SWISS NATIONAL BANK	0.08%	44.76K	1.26M	0	0
Mar 31, 2026	MILLENNIUM MANAGEMENT LLC	0.31%	181.95K	5.14M	-66.91K	-26.89%
Mar 31, 2026	JANE STREET GROUP, LLC	0%	0	-	-73.11K	-100.00%
Mar 31, 2026	ALPS ADVISORS INC	0.09%	52.15K	1.47M	-444	-0.84%
Mar 31, 2026	DEUTSCHE BANK AG\	0.09%	53.72K	1.52M	-2.67K	-4.73%
Mar 31, 2026	TD ASSET MANAGEMENT INC	0.09%	54.83K	1.55M	-65.42K	-54.41%
Mar 31, 2026	UBS GROUP AG	0.12%	71.94K	2.03M	-65.79K	-47.77%
Mar 31, 2026	UBS ASSET MANAGEMENT AMERICAS INC	0.13%	77.65K	2.19M	-6.3K	-7.51%
Mar 31, 2026	NORTHERN TRUST CORP	0.14%	83.47K	2.36M	2.43K	+3.00%
Mar 31, 2026	EQT FUND MANAGEMENT S.A R.L.	5.79%	3.42M	96.75M	0	0
Mar 31, 2026		0.28%	167.01K	4.72M	167.01K	+100.00%
Mar 31, 2026	CITADEL ADVISORS LLC	0.28%	168.63K	4.76M	33.56K	+24.85%
Mar 31, 2026	FORESITE CAPITAL MANAGEMENT V, LLC	0.33%	194.13K	5.48M	194.13K	+100.00%
Mar 31, 2026	ORBIMED ADVISORS LLC	0.35%	205.4K	5.8M	0	0
Mar 31, 2026	D. E. SHAW & CO., INC.	0.54%	321.16K	9.07M	60.59K	+23.25%
Mar 31, 2026	BOOTHBAY FUND MANAGEMENT, LLC	0.27%	157.12K	4.44M	0	0
Mar 31, 2026	TFG ASSET MANAGEMENT GP LTD	0.37%	221.61K	6.26M	27K	+13.87%
Mar 31, 2026	BLACKROCK, INC.	1.28%	757.21K	21.39M	48.66K	+6.87%
Mar 31, 2026	NOVO HOLDINGS A/S	2.96%	1.75M	49.44M	0	0
Mar 31, 2026	COMMODORE CAPITAL LP	3.24%	1.92M	54.21M	29.53K	+1.56%
Mar 31, 2026	VENBIO PARTNERS LLC	7.84%	4.64M	131.06M	0	0
Mar 31, 2026	ALYESKA INVESTMENT GROUP, L.P.	0.21%	125K	3.53M	0	0
Mar 31, 2026	TWO SIGMA INVESTMENTS, LP	0.21%	126.08K	3.56M	-89.11K	-41.41%
Mar 31, 2026	STATE STREET CORP	0.26%	152.95K	4.32M	-8.55K	-5.30%
Mar 31, 2026	SCHRODER INVESTMENT MANAGEMENT GROUP	0.27%	158.02K	4.31M	0	0
Mar 31, 2026	MORGAN STANLEY	0.28%	164.32K	4.64M	-84.01K	-33.83%
Mar 31, 2026	OCTAGON CAPITAL ADVISORS LP	0.28%	165K	4.66M	-506.47K	-75.43%
Mar 31, 2026	PRICE T ROWE ASSOCIATES INC /MD/	0.75%	442.26K	12.49M	-499.35K	-53.03%
Mar 31, 2026	BALYASNY ASSET MANAGEMENT L.P.	0.78%	462.25K	13.06M	-34.01K	-6.85%
Mar 31, 2026	DV TRADING LLC	0.24%	143.97K	4.07M	143.97K	+100.00%
Mar 31, 2026	KYNAM CAPITAL MANAGEMENT, LP	1.08%	640.4K	18.09M	0	0
Mar 31, 2026	ROCK SPRINGS CAPITAL MANAGEMENT LP	1.09%	645.53K	18.24M	22.13K	+3.55%
Mar 31, 2026	SOLEUS CAPITAL MANAGEMENT, L.P.	1.19%	702.05K	19.83M	0	0
Mar 31, 2026	POLAR CAPITAL HOLDINGS PLC	1.32%	781.02K	22.06M	543.05K	+228.21%
Mar 31, 2026	5AM VENTURE MANAGEMENT, LLC	1.35%	797.6K	22.53M	0	0
Mar 31, 2026	SOFINNOVA INVESTMENTS, INC.	1.38%	818.33K	23.12M	73.16K	+9.82%
Mar 31, 2026	CORMORANT ASSET MANAGEMENT, LP	1.69%	1M	28.25M	-83K	-7.66%
Mar 31, 2026	IKARIAN CAPITAL, LLC	0.82%	486.86K	13.75M	0	0
Mar 31, 2026	PATIENT SQUARE CAPITAL LP	0.83%	493K	13.93M	-49.7K	-9.16%
Mar 31, 2026	POINT72 ASSET MANAGEMENT, L.P.	1.7%	1.01M	28.45M	295.39K	+41.51%
Mar 31, 2026	SQUAREPOINT OPS LLC	0.16%	96.38K	2.72M	-3.98K	-3.96%
Mar 31, 2026	BAKER BROS. ADVISORS LP	0.63%	375K	10.59M	0	0
Mar 31, 2026	EVERSEPT PARTNERS, LP	0.69%	406.96K	11.5M	-32.22K	-7.34%
Mar 31, 2026	FORESITE CAPITAL MANAGEMENT IV, LLC	8.08%	4.78M	134.99M	0	0
Mar 31, 2026	FMR LLC	10.62%	6.28M	177.54M	-114.69K	-1.79%
Mar 31, 2026	GEODE CAPITAL MANAGEMENT, LLC	0.15%	89.13K	2.52M	2.33K	+2.68%
Mar 31, 2026	HIGHVISTA STRATEGIES LLC	0.17%	97.87K	2.76M	-64.5K	-39.73%
Mar 31, 2026	ADAR1 CAPITAL MANAGEMENT, LLC	0.18%	105.53K	2.98M	20K	+23.38%
Mar 31, 2026	GENERAL ATLANTIC, L.P.	13.58%	8.03M	226.88M	0	0
Mar 31, 2026	STEMPOINT CAPITAL LP	0.15%	86.64K	2.45M	28.25K	+48.38%
Mar 31, 2026	GOLDMAN SACHS GROUP INC	0.24%	142.93K	4.04M	-17.98K	-11.17%
Dec 31, 2025	CITADEL ADVISORS LLC	0.22%	135.07K	3.75M	5.33K	+4.11%
Dec 31, 2025	TWO SIGMA INVESTMENTS, LP	0.35%	215.19K	5.97M	204.58K	+1,928.74%
Dec 31, 2025	MILLENNIUM MANAGEMENT LLC	0.4%	248.86K	6.91M	142.31K	+133.56%
Dec 31, 2025	HRT FINANCIAL LP	0.02%	14.76K	409K	-11.44K	-43.65%
Dec 31, 2025	ROYAL BANK OF CANADA	0%	80	2K	4	+5.26%
Dec 31, 2025	DAIWA SECURITIES GROUP INC.	0%	213	6K	213	+100.00%
Dec 31, 2025	WELLS FARGO & COMPANY/MN	0%	450	12.49K	450	+100.00%
Dec 31, 2025	GF FUND MANAGEMENT CO. LTD.	0%	1.26K	34.91K	1.26K	+100.00%
Dec 31, 2025	CITIGROUP INC	0%	1.79K	49.59K	1.22K	+216.84%
Dec 31, 2025	BARCLAYS PLC	0%	2.78K	77.01K	2.78K	+100.00%
Dec 31, 2025	MIRAE ASSET GLOBAL INVESTMENTS CO., LTD.	0.01%	3.11K	86.39K	3.11K	+100.00%
Dec 31, 2025	ZURCHER KANTONALBANK (ZURICH CANTONALBANK)	0.01%	3.98K	110.42K	3.98K	+100.00%
Dec 31, 2025	PALUMBO WEALTH MANAGEMENT LLC	0.03%	20.18K	560.05K	3.54K	+21.28%
Dec 31, 2025		0.32%	198.77K	5.52M	198.77K	+100.00%
Dec 31, 2025	JPMORGAN CHASE & CO	0.04%	21.94K	608.89K	-5.14K	-18.99%
Dec 31, 2025	LEGAL & GENERAL GROUP PLC	0.04%	22.67K	628.98K	0	0
Dec 31, 2025	JUMP FINANCIAL, LLC	0.04%	26.3K	729.83K	26.3K	+100.00%
Dec 31, 2025	BIRCHVIEW CAPITAL, LP	0.05%	29.85K	828.25K	15K	+101.03%
Dec 31, 2025	MARSHALL WACE, LLP	0.05%	31.83K	883.34K	4.74K	+17.48%
Dec 31, 2025	TUDOR INVESTMENT CORP ET AL	0.05%	32.03K	888.78K	-45.86K	-58.88%
Dec 31, 2025	SWISS NATIONAL BANK	0.07%	44.76K	1.24M	2.4K	+5.67%
Dec 31, 2025	ALPS ADVISORS INC	0.08%	52.59K	1.46M	52.59K	+100.00%
Dec 31, 2025	DEUTSCHE BANK AG\	0.09%	56.39K	1.56M	4.58K	+8.85%
Dec 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.09%	59.04K	1.64M	58.62K	+14,194.67%
Dec 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.1%	60.1K	1.67M	60.1K	+100.00%
Dec 31, 2025	TFG ASSET MANAGEMENT GP LTD	0.31%	194.61K	5.4M	0	0
Dec 31, 2025	VENBIO PARTNERS LLC	7.45%	4.64M	128.74M	0	0
Dec 31, 2025	TD ASSET MANAGEMENT INC	0.19%	120.25K	3.34M	15.89K	+15.23%
Dec 31, 2025	ALYESKA INVESTMENT GROUP, L.P.	0.2%	125K	3.47M	0	0
Dec 31, 2025	UBS GROUP AG	0.22%	137.73K	3.82M	6.98K	+5.34%
Dec 31, 2025	BAKER BROS. ADVISORS LP	0.6%	375K	10.41M	0	0
Dec 31, 2025	EVERSEPT PARTNERS, LP	0.71%	439.18K	12.19M	439.18K	+100.00%
Dec 31, 2025	IKARIAN CAPITAL, LLC	0.78%	486.86K	13.51M	276.69K	+131.65%
Dec 31, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	0.14%	85.53K	2.37M	51.4K	+150.64%
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.14%	86.8K	2.41M	8.26K	+10.52%
Dec 31, 2025	SQUAREPOINT OPS LLC	0.16%	100.36K	2.78M	100.36K	+100.00%
Dec 31, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.25%	157.12K	4.36M	21.94K	+16.23%
Dec 31, 2025	SCHRODER INVESTMENT MANAGEMENT GROUP	0.25%	158.02K	4.15M	145.95K	+1,208.86%
Dec 31, 2025	HIGHVISTA STRATEGIES LLC	0.26%	162.37K	4.51M	162.37K	+100.00%
Dec 31, 2025	ORBIMED ADVISORS LLC	0.33%	205.4K	5.7M	205.4K	+100.00%
Dec 31, 2025	POLAR CAPITAL HOLDINGS PLC	0.38%	237.96K	6.6M	-26.73K	-10.10%
Dec 31, 2025	D. E. SHAW & CO., INC.	0.42%	260.57K	7.23M	237.69K	+1,038.57%
Dec 31, 2025	BALYASNY ASSET MANAGEMENT L.P.	0.8%	496.26K	13.77M	-129.5K	-20.69%
Dec 31, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	1%	623.4K	17.3M	0	0
Dec 31, 2025	KYNAM CAPITAL MANAGEMENT, LP	1.03%	640.4K	17.77M	-34.61K	-5.13%
Dec 31, 2025	OCTAGON CAPITAL ADVISORS LP	1.08%	671.47K	18.63M	-51.13K	-7.08%
Dec 31, 2025	POINT72 ASSET MANAGEMENT, L.P.	1.14%	711.63K	19.75M	192.24K	+37.01%
Dec 31, 2025	5AM VENTURE MANAGEMENT, LLC	1.28%	797.6K	22.13M	0	0
Dec 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.51%	941.61K	26.13M	124.8K	+15.28%
Dec 31, 2025	CORMORANT ASSET MANAGEMENT, LP	1.74%	1.08M	30.05M	-280.2K	-20.55%
Dec 31, 2025	SATURN V CAPITAL MANAGEMENT LLC	1.83%	1.14M	31.64M	253.7K	+28.62%
Dec 31, 2025	NOVO HOLDINGS A/S	2.81%	1.75M	48.56M	0	0
Dec 31, 2025	COMMODORE CAPITAL LP	3.04%	1.89M	52.43M	-529.03K	-21.87%
Dec 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	3.06%	1.91M	52.89M	171.05K	+9.86%
Dec 31, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	4.5%	2.8M	77.76M	-379.19K	-11.92%
Dec 31, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	5.02%	3.13M	86.75M	683.58K	+27.99%
Dec 31, 2025	VIKING GLOBAL INVESTORS LP	5.87%	3.65M	101.38M	0	0
Dec 31, 2025	FORESITE CAPITAL MANAGEMENT IV, LLC	7.68%	4.78M	132.61M	0	0
Dec 31, 2025	FMR LLC	10.28%	6.4M	177.58M	0	0
Dec 31, 2025	GENERAL ATLANTIC, L.P.	12.9%	8.03M	222.87M	0	0
Dec 31, 2025	QUARRY LP	0%	0	-	-442	-100.00%
Dec 31, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0%	0	-	-183.9K	-100.00%
Dec 31, 2025	SBI SECURITIES CO., LTD.	0%	1	28	-2	-66.67%
Dec 31, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.13%	79.89K	2.1M	20.1K	+33.62%
Dec 31, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.13%	83.95K	2.33M	83.95K	+100.00%
Dec 31, 2025	GOLDMAN SACHS GROUP INC	0.26%	160.91K	4.47M	146.43K	+1,011.56%
Dec 31, 2025	STATE STREET CORP	0.26%	161.5K	4.48M	18.72K	+13.11%
Dec 31, 2025	MORGAN STANLEY	0.4%	248.33K	6.89M	190.07K	+326.23%
Dec 31, 2025	PATIENT SQUARE CAPITAL LP	0.87%	542.7K	15.06M	197.32K	+57.13%
Dec 31, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	1.13%	702.05K	19.48M	55K	+8.50%
Dec 31, 2025	BLACKROCK, INC.	1.14%	708.56K	19.66M	294.14K	+70.98%
Dec 31, 2025	SOFINNOVA INVESTMENTS, INC.	1.2%	745.17K	20.68M	5.29K	+0.72%
Dec 31, 2025	EQT FUND MANAGEMENT S.A R.L.	5.5%	3.42M	95.03M	0	0
Dec 31, 2025	QUANTBOT TECHNOLOGIES LP	0.01%	4.26K	118.22K	4.26K	+100.00%
Dec 31, 2025	NANO CAP NEW MILLENNIUM GROWTH FUND L P	0.01%	5K	138.75M	5K	+100.00%
Dec 31, 2025	KLP KAPITALFORVALTNING AS	0.01%	5.8K	160.95K	0	0
Dec 31, 2025	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0.01%	8.24K	228.63K	2.75K	+50.10%
Dec 31, 2025	TEACHER RETIREMENT SYSTEM OF TEXAS	0.01%	8.91K	247.28K	8.91K	+100.00%
Dec 31, 2025	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.02%	10.44K	289.66K	7.44K	+247.93%
Dec 31, 2025	VIRTUS INVESTMENT ADVISERS, INC.	0.02%	11.01K	305.56K	4.41K	+66.73%
Dec 31, 2025	JANE STREET GROUP, LLC	0.02%	12.6K	349.65M	12.6K	+100.00%
Dec 31, 2025	NUVEEN, LLC	0.03%	17.01K	471.94K	0	0
Dec 31, 2025	VERITION FUND MANAGEMENT LLC	0.03%	17.9K	496.67K	17.9K	+100.00%
Dec 31, 2025	XTX TOPCO LTD	0.03%	18.57K	515.26K	10.36K	+126.08%
Dec 31, 2025	VANGUARD GROUP INC	0.03%	19.31K	535.85M	0	0
Dec 31, 2025	BANK OF AMERICA CORP /DE/	0.03%	19.56K	542.71M	901	+4.83%
Dec 31, 2025	TWO SIGMA ADVISERS, LP	0.14%	89.6K	2.49M	89.6K	+100.00%
Dec 31, 2025	LOGOS GLOBAL MANAGEMENT LP	0.16%	100K	2.78M	-50K	-33.33%
Sep 30, 2025	DEUTSCHE BANK AG\	0.08%	51.81K	1.29M	23.62K	+83.80%
Sep 30, 2025	FORESITE CAPITAL MANAGEMENT IV, LLC	7.68%	4.78M	119.23M	368K	+8.34%
Sep 30, 2025	AMUNDI	0.08%	41.52K	965.27K	14.1K	+51.43%
Sep 30, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	0.06%	34.12K	851.39K	0	0
Sep 30, 2025	VENBIO PARTNERS LLC	7.45%	4.64M	115.75M	350K	+8.16%
Sep 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.31%	816.81K	20.38M	49.49K	+6.45%
Sep 30, 2025	STATE STREET CORP	0.23%	142.78K	3.56M	49.1K	+52.42%
Sep 30, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.22%	135.18K	3.37M	118.99K	+735.12%
Sep 30, 2025	UBS GROUP AG	0.21%	130.75K	3.26M	127.01K	+3,393.24%
Sep 30, 2025	CITADEL ADVISORS LLC	0.21%	129.74K	3.24M	100.52K	+343.99%
Sep 30, 2025	ALYESKA INVESTMENT GROUP, L.P.	0.2%	125K	3.12M	125K	+100.00%
Sep 30, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.19%	119.41K	2.98M	-190.53K	-61.47%
Sep 30, 2025	GENERAL ATLANTIC, L.P.	12.9%	8.03M	200.38M	500K	+6.64%
Sep 30, 2025	FMR LLC	10.28%	6.4M	159.66M	976.77K	+18.01%
Sep 30, 2025	BLACKROCK, INC.	0.67%	414.42K	10.34M	213.33K	+106.09%
Sep 30, 2025	MARSHALL WACE, LLP	0.05%	27.1K	676.05K	27.1K	+100.00%
Sep 30, 2025	JPMORGAN CHASE & CO	0.05%	27.09K	675.77K	23.74K	+710.44%
Sep 30, 2025	LEGAL & GENERAL GROUP PLC	0.04%	22.67K	565.52K	11.12K	+96.24%
Sep 30, 2025	VANGUARD GROUP INC	0.04%	19.31K	481.79K	19.31K	+100.00%
Sep 30, 2025	NUVEEN, LLC	0.03%	17.01K	424.33K	17.01K	+100.00%
Sep 30, 2025	PALUMBO WEALTH MANAGEMENT LLC	0.03%	16.64K	415.19K	2.09K	+14.38%
Sep 30, 2025	BIRCHVIEW CAPITAL, LP	0.03%	14.85K	370.43K	14.85K	+100.00%
Sep 30, 2025	SCHRODER INVESTMENT MANAGEMENT GROUP	0.02%	12.07K	292.89K	12.07K	+100.00%
Sep 30, 2025	KLP KAPITALFORVALTNING AS	0.01%	5.8K	144.71K	0	0
Sep 30, 2025	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0.01%	5.49K	136.95K	3.12K	+131.70%
Sep 30, 2025	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	0.01%	3.26K	81K	0	0
Sep 30, 2025	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.01%	3K	74.85K	3K	+100.00%
Sep 30, 2025	CITIGROUP INC	0%	564	14.07K	7	+1.26%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0%	413	10.3K	54	+15.04%
Sep 30, 2025	CENTERPOINT ADVISORS, LLC	0%	100	2K	0	0
Sep 30, 2025	SBI SECURITIES CO., LTD.	0%	3	75	2	+200.00%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0%	0	-	-1K	-100.00%
Sep 30, 2025	BARCLAYS PLC	0%	0	-	-2.8K	-100.00%
Sep 30, 2025	ALPS ADVISORS INC	0%	0	-	-29.4K	-100.00%
Sep 30, 2025	ROSALIND ADVISORS, INC.	0%	0	-	-223.63K	-100.00%
Sep 30, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	3.92%	2.44M	60.94M	425K	+21.07%
Sep 30, 2025	PARADIGM BIOCAPITAL ADVISORS LP	2.95%	1.84M	45.8M	772.58K	+72.69%
Sep 30, 2025	OCTAGON CAPITAL ADVISORS LP	1.16%	722.6K	18.03M	50K	+7.43%
Sep 30, 2025	KYNAM CAPITAL MANAGEMENT, LP	1.08%	675K	16.84M	675K	+100.00%
Sep 30, 2025	VR ADVISER, LLC	1.08%	674.6K	16.83M	-1.37M	-67.05%
Sep 30, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	1.04%	647.05K	16.14M	-85.92K	-11.72%
Sep 30, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	1%	623.4K	15.55M	0	0
Sep 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.83%	519.38K	12.96M	481.77K	+1,280.89%
Sep 30, 2025	VIKING GLOBAL INVESTORS LP	5.87%	3.65M	91.15M	0	0
Sep 30, 2025	EQT FUND MANAGEMENT S.A R.L.	5.5%	3.42M	85.44M	3.42M	+100.00%
Sep 30, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	5.11%	3.18M	79.37M	-122.11K	-3.70%
Sep 30, 2025	NOVO HOLDINGS A/S	2.81%	1.75M	43.66M	25K	+1.45%
Sep 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	2.79%	1.73M	43.28M	1.73M	+100.00%
Sep 30, 2025	CORMORANT ASSET MANAGEMENT, LP	2.19%	1.36M	34.01M	-91.46K	-6.29%
Sep 30, 2025	5AM VENTURE MANAGEMENT, LLC	1.28%	797.6K	19.9M	0	0
Sep 30, 2025	TUDOR INVESTMENT CORP ET AL	0.14%	77.89K	1.94M	77.89K	+100.00%
Sep 30, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.1%	59.79K	1.49M	10.93K	+22.38%
Sep 30, 2025	COMMODORE CAPITAL LP	3.88%	2.42M	60.34M	507.04K	+26.53%
Sep 30, 2025	BAKER BROS. ADVISORS LP	0.6%	375K	9.36M	375K	+100.00%
Sep 30, 2025	PATIENT SQUARE CAPITAL LP	0.55%	345.38K	8.62M	101.1K	+41.39%
Sep 30, 2025	POLAR CAPITAL HOLDINGS PLC	0.43%	264.69K	6.6M	264.69K	+100.00%
Sep 30, 2025	IKARIAN CAPITAL, LLC	0.34%	210.17K	5.24M	210.17K	+100.00%
Sep 30, 2025	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.32%	200K	4.99M	200K	+100.00%
Sep 30, 2025	TFG ASSET MANAGEMENT GP LTD	0.31%	194.61K	4.86M	6.51K	+3.46%
Sep 30, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.3%	183.9K	4.59M	183.9K	+100.00%
Sep 30, 2025	GREAT POINT PARTNERS LLC	0.25%	155.11K	3.87M	155.11K	+100.00%
Sep 30, 2025	LOGOS GLOBAL MANAGEMENT LP	0.24%	150K	3.74M	150K	+100.00%
Sep 30, 2025	MILLENNIUM MANAGEMENT LLC	0.17%	106.55K	2.66M	93.26K	+702.02%
Sep 30, 2025	TD ASSET MANAGEMENT INC	0.17%	104.36K	2.6M	4.85K	+4.87%
Sep 30, 2025	WOODLINE PARTNERS LP	0.16%	100K	2.5M	100K	+100.00%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.13%	78.54K	1.96M	24.44K	+45.17%
Sep 30, 2025	NORTHERN TRUST CORP	0.13%	77.96K	1.94M	-17.31K	-18.17%
Sep 30, 2025	MORGAN STANLEY	0.09%	58.26K	1.45M	-1.51K	-2.52%
Sep 30, 2025	SWISS NATIONAL BANK	0.07%	42.36K	1.06M	16.1K	+61.32%
Sep 30, 2025	SATURN V CAPITAL MANAGEMENT LLC	1.42%	886.33K	22.11M	886.33K	+100.00%
Sep 30, 2025	SOFINNOVA INVESTMENTS, INC.	1.19%	739.88K	18.46M	154.34K	+26.36%
Sep 30, 2025	BALYASNY ASSET MANAGEMENT L.P.	1.01%	625.76K	15.61M	625.76K	+100.00%
Jun 30, 2025	VENBIO PARTNERS LLC	7.87%	4.29M	75.49M	0	0
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0.03%	16.02K	282.01K	-13.18K	-45.14%
Jun 30, 2025	TFG ASSET MANAGEMENT GP LTD	0.35%	188.1K	3.31M	61.11K	+48.12%
Jun 30, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.57%	309.93K	5.45M	-73.93K	-19.26%
Jun 30, 2025	SOFINNOVA INVESTMENTS, INC.	1.07%	585.53K	10.31M	-7.87K	-1.33%
Jun 30, 2025	UBS GROUP AG	0.01%	3.74K	65.88K	-3.71K	-49.75%
Jun 30, 2025	COMMODORE CAPITAL LP	3.51%	1.91M	33.64M	0	0
Jun 30, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	3.7%	2.02M	35.51M	0	0
Jun 30, 2025	JPMORGAN CHASE & CO	0.01%	3.34K	58.82K	783	+30.60%
Jun 30, 2025	PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO	0.01%	4.5K	79.2K	0	0
Jun 30, 2025	VIRTUS INVESTMENT ADVISERS, INC.	0.01%	5.46K	96.04K	-3.18K	-36.81%
Jun 30, 2025	CENTERPOINT ADVISORS, LLC	0%	100	2K	100	+100.00%
Jun 30, 2025	VANGUARD GROUP INC	0%	0	-	-12.74K	-100.00%
Jun 30, 2025	CORMORANT ASSET MANAGEMENT, LP	2.67%	1.45M	25.6M	-11.8K	-0.80%
Jun 30, 2025	HIGHVISTA STRATEGIES LLC	0.04%	23.74K	417.81K	971	+4.26%
Jun 30, 2025	SWISS NATIONAL BANK	0.05%	26.26K	462.12K	0	0
Jun 30, 2025	DEUTSCHE BANK AG\	0.05%	28.19K	496.07K	12	+0.04%
Jun 30, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	0.06%	34.12K	600.58K	34.12K	+100.00%
Jun 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.07%	37.61K	661.97K	-14.96K	-28.46%
Jun 30, 2025	TD ASSET MANAGEMENT INC	0.18%	99.51K	1.75M	21.39K	+27.38%
Jun 30, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	1.14%	623.4K	10.97M	0	0
Jun 30, 2025	VR ADVISER, LLC	3.76%	2.05M	36.04M	-1.07M	-34.22%
Jun 30, 2025	FORESITE CAPITAL MANAGEMENT IV, LLC	8.09%	4.41M	77.63M	0	0
Jun 30, 2025	CUBIST SYSTEMATIC STRATEGIES, LLC	0%	2.56K	45.07K	283	+12.42%
Jun 30, 2025	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0.03%	14.05K	247.25M	1.26K	+9.83%
Jun 30, 2025	POINT72 ASIA (SINGAPORE) PTE. LTD.	0%	369	6.49K	369	+100.00%
Jun 30, 2025		0%	2.37K	41.69K	0	0
Jun 30, 2025	ALPS ADVISORS INC	0.05%	29.4K	517.41K	-7.24K	-19.75%
Jun 30, 2025	BLACKROCK, INC.	0.37%	201.09K	3.54M	8.22K	+4.26%
Jun 30, 2025	NOVO HOLDINGS A/S	3.16%	1.73M	30.36M	0	0
Jun 30, 2025	FMR LLC	9.95%	5.42M	95.43M	27.02K	+0.50%
Jun 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0%	359	6.32M	201	+127.22%
Jun 30, 2025	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	0.01%	3.26K	57K	3.26K	+100.00%
Jun 30, 2025	LEGAL & GENERAL GROUP PLC	0.02%	11.55K	203.28K	1.7K	+17.20%
Jun 30, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.09%	48.86K	859.88K	7.88K	+19.23%
Jun 30, 2025	PARADIGM BIOCAPITAL ADVISORS LP	1.95%	1.06M	18.71M	1.06M	+100.00%
Jun 30, 2025	GENERAL ATLANTIC, L.P.	13.81%	7.53M	132.55M	0	0
Jun 30, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.03%	16.19K	284.89K	16.19K	+100.00%
Jun 30, 2025	MORGAN STANLEY	0.11%	59.77K	1.05B	-15.59K	-20.69%
Jun 30, 2025	ROSALIND ADVISORS, INC.	0.41%	223.63K	3.94M	0	0
Jun 30, 2025	PATIENT SQUARE CAPITAL LP	0.45%	244.28K	4.3M	-1.21K	-0.49%
Jun 30, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	6.06%	3.3M	58.14M	0	0
Jun 30, 2025	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0%	2.37K	41.69K	0	0
Jun 30, 2025	KLP KAPITALFORVALTNING AS	0.01%	5.8K	102.08K	0	0
Jun 30, 2025	CITADEL ADVISORS LLC	0.05%	29.22K	514.29M	29.22K	+100.00%
Jun 30, 2025	OCTAGON CAPITAL ADVISORS LP	1.23%	672.6K	11.84M	-97.22K	-12.63%
Jun 30, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	1.34%	732.97K	12.9M	-81.68K	-10.03%
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.41%	767.32K	13.51M	181.23K	+30.92%
Jun 30, 2025	5AM VENTURE MANAGEMENT, LLC	1.46%	797.6K	14.04M	0	0
Jun 30, 2025	BARCLAYS PLC	0.01%	2.8K	49K	-65	-2.27%
Jun 30, 2025	ROYAL BANK OF CANADA	0%	58	1K	58	+100.00%
Jun 30, 2025	VIKING GLOBAL INVESTORS LP	6.7%	3.65M	64.3M	0	0
Jun 30, 2025	MILLENNIUM MANAGEMENT LLC	0.02%	13.29K	233.82K	13.29K	+100.00%
Jun 30, 2025	PALUMBO WEALTH MANAGEMENT LLC	0.03%	14.55K	256.06K	447	+3.17%
Jun 30, 2025	AMUNDI	0.05%	27.42K	488.57K	27.42K	+2,741,600.00%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.1%	54.1K	951.94K	15.77K	+41.14%
Jun 30, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.1%	55.38K	974.64K	-12.95K	-18.96%
Jun 30, 2025	STATE STREET CORP	0.17%	93.67K	1.65M	-111	-0.12%
Jun 30, 2025	NORTHERN TRUST CORP	0.17%	95.27K	1.68M	8.39K	+9.66%
Mar 31, 2025		0%	2.37K	37.19K	0	0
Mar 31, 2025	DEUTSCHE BANK AG\	0.05%	28.17K	442.33K	10.01K	+55.07%
Mar 31, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.1%	52.57K	825.41K	44.65K	+563.73%
Mar 31, 2025	MORGAN STANLEY	0.14%	75.37K	1.18M	48.37K	+179.16%
Mar 31, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.71%	383.86K	6.03M	-4.33K	-1.11%
Mar 31, 2025	GENERAL ATLANTIC, L.P.	13.93%	7.53M	118.24M	0	0
Mar 31, 2025	PALUMBO WEALTH MANAGEMENT LLC	0.03%	14.1K	221.4K	3.88K	+37.97%
Mar 31, 2025	PATIENT SQUARE CAPITAL LP	0.45%	245.5K	3.85M	37.89K	+18.25%
Mar 31, 2025	VIRTUS INVESTMENT ADVISERS, INC.	0.02%	8.64K	135.59K	8.64K	+100.00%
Mar 31, 2025	LEGAL & GENERAL GROUP PLC	0.02%	9.86K	154.72K	0	0
Mar 31, 2025	TFG ASSET MANAGEMENT GP LTD	0.23%	127K	1.99M	127K	+100.00%
Mar 31, 2025	BLACKROCK, INC.	0.36%	192.87K	3.03M	-1.33K	-0.68%
Mar 31, 2025	PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO	0.01%	4.5K	70.65K	1K	+28.57%
Mar 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0%	158	2.48K	58	+58.00%
Mar 31, 2025	CITIGROUP INC	0%	543	8.53K	0	0
Mar 31, 2025	WELLS FARGO & COMPANY/MN	0%	950	14.92K	150	+18.75%
Mar 31, 2025	VANGUARD GROUP INC	0.02%	12.74K	200.02K	0	0
Mar 31, 2025	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0.02%	12.79K	200.82K	-635	-4.73%
Mar 31, 2025	SWISS NATIONAL BANK	0.05%	26.26K	412.24K	0	0
Mar 31, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.08%	40.98K	643.36K	0	0
Mar 31, 2025	TD ASSET MANAGEMENT INC	0.14%	78.12K	1.23M	22.91K	+41.48%
Mar 31, 2025	ROSALIND ADVISORS, INC.	0.41%	223.63K	3.51M	223.63K	+100.00%
Mar 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.08%	586.09K	9.2M	142.19K	+32.03%
Mar 31, 2025	SOFINNOVA INVESTMENTS, INC.	1.1%	593.4K	9.32M	32.68K	+5.83%
Mar 31, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	1.15%	623.4K	9.79M	-151.73K	-19.57%
Mar 31, 2025	OCTAGON CAPITAL ADVISORS LP	1.42%	769.82K	12.09M	-8.19K	-1.05%
Mar 31, 2025	5AM VENTURE MANAGEMENT, LLC	1.48%	797.6K	12.52M	0	0
Mar 31, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	1.51%	814.65K	12.79M	0	0
Mar 31, 2025	CORMORANT ASSET MANAGEMENT, LP	2.71%	1.47M	23.02M	0	0
Mar 31, 2025	NOVO HOLDINGS A/S	3.19%	1.73M	27.08M	0	0
Mar 31, 2025	COMMODORE CAPITAL LP	3.54%	1.91M	30.01M	0	0
Mar 31, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	3.73%	2.02M	31.67M	0	0
Mar 31, 2025	VR ADVISER, LLC	5.76%	3.11M	48.87M	-107.41K	-3.34%
Mar 31, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	6.11%	3.3M	51.86M	0	0
Mar 31, 2025	VIKING GLOBAL INVESTORS LP	6.76%	3.65M	57.36M	0	0
Mar 31, 2025	VENBIO PARTNERS LLC	7.93%	4.29M	67.34M	0	0
Mar 31, 2025	FORESITE CAPITAL MANAGEMENT IV, LLC	8.16%	4.41M	69.25M	12.7K	+0.29%
Mar 31, 2025	FMR LLC	9.98%	5.4M	84.71M	0	0
Mar 31, 2025	JPMORGAN CHASE & CO	0%	2.56K	40.18K	-541	-17.45%
Mar 31, 2025	HIGHVISTA STRATEGIES LLC	0.04%	22.77K	357.46K	0	0
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0.05%	29.21K	458.53K	-1.6K	-5.20%
Mar 31, 2025	ALPS ADVISORS INC	0.07%	36.63K	575.14K	-7.04K	-16.12%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.07%	38.33K	601.83K	0	0
Mar 31, 2025	CUBIST SYSTEMATIC STRATEGIES, LLC	0%	2.28K	35.76K	-1.06K	-31.71%
Mar 31, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.13%	68.33K	1.07M	4.6K	+7.21%
Mar 31, 2025	UBS GROUP AG	0.01%	7.45K	116.95K	6.4K	+612.82%
Mar 31, 2025	STATE STREET CORP	0.17%	93.78K	1.47M	1.78K	+1.93%
Mar 31, 2025	NORTHERN TRUST CORP	0.16%	86.88K	1.36M	-5.06K	-5.50%
Mar 31, 2025	BARCLAYS PLC	0.01%	2.86K	45K	-3	-0.10%
Mar 31, 2024	VENBIO PARTNERS LLC	8.2%	4.29M	99.13M	-630.2K	-12.81%
Mar 31, 2024	QUARRY LP	0%	0	-	-750	-100.00%
Mar 31, 2024	VIVO CAPITAL, LLC	0%	0	-	-285K	-100.00%
Mar 31, 2024	SCHONFELD STRATEGIC ADVISORS LLC	0%	0	-	-12.4K	-100.00%
Mar 31, 2024	BLACKSTONE INC.	0%	0	-	-100K	-100.00%
Mar 31, 2024	TWO SIGMA INVESTMENTS, LP	0%	0	-	-8.2K	-100.00%
Mar 31, 2024	UBS OCONNOR LLC	0%	0	-	-18K	-100.00%
Mar 31, 2024	PIPER SANDLER & CO.	0%	0	-	-181	-100.00%
Mar 31, 2024	ADAR1 CAPITAL MANAGEMENT, LLC	0%	2K	46.22K	2K	+100.00%
Mar 31, 2024	BLACKROCK INC.	0%	2.27K	52.41K	0	0
Mar 31, 2024	JPMORGAN CHASE & CO	0.01%	3.15K	72.8K	2.96K	+1,557.89%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.01%	7.81K	180.44K	7.81K	+100.00%
Mar 31, 2024	JUMP FINANCIAL, LLC	0.02%	11.7K	270.39K	11.7K	+100.00%
Mar 31, 2024	HIGHVISTA STRATEGIES LLC	0.03%	16.75K	387.09K	16.75K	+100.00%
Mar 31, 2024	HUDSON BAY CAPITAL MANAGEMENT LP	0.04%	20.02K	462.62K	-50.12K	-71.46%
Mar 31, 2024	MILLENNIUM MANAGEMENT LLC	0.04%	20.53K	474.38K	-167.99K	-89.11%
Mar 31, 2024	MORGAN STANLEY	0.06%	29.04K	671.14K	6.55K	+29.14%
Mar 31, 2024	QUBE RESEARCH & TECHNOLOGIES LTD	0.06%	30.14K	696.49K	-2.18K	-6.75%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.06%	31.12K	719.09K	22.57K	+263.97%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	0.06%	31.22K	721.59K	9.63K	+44.59%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.11%	55.08K	1.27M	0	0
Mar 31, 2024	MARSHALL WACE, LLP	0.11%	58.17K	1.34M	-1.96K	-3.25%
Mar 31, 2024	WALLEYE CAPITAL LLC	0.19%	97.18K	2.25M	19.31K	+24.80%
Mar 31, 2024	TD ASSET MANAGEMENT INC	0.22%	112.62K	2.6M	112.62K	+100.00%
Mar 31, 2024	CITADEL ADVISORS LLC	0.46%	238.31K	5.51M	96.85K	+68.46%
Mar 31, 2024	ROCK SPRINGS CAPITAL MANAGEMENT LP	1.44%	752.92K	17.4M	752.92K	+100.00%
Mar 31, 2024	SPHERA FUNDS MANAGEMENT LTD.	0.75%	392.88K	9.08M	147.88K	+60.36%
Mar 31, 2024	SOLEUS CAPITAL MANAGEMENT, L.P.	0.77%	401.9K	9.29M	184.51K	+84.87%
Mar 31, 2024	SOFINNOVA INVESTMENTS, INC.	1.12%	584.67K	13.51M	74.23K	+14.54%
Mar 31, 2024	FMR LLC	9.93%	5.19M	120.01M	0	0
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	1.45%	757.92K	17.52M	-84.78K	-10.06%
Mar 31, 2024	5AM VENTURE MANAGEMENT, LLC	1.53%	797.6K	18.43M	0	0
Mar 31, 2024	ECOR1 CAPITAL, LLC	1.72%	900K	20.8M	0	0
Mar 31, 2024	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	2.03%	1.06M	24.53M	249.36K	+30.70%
Mar 31, 2024	NOVO HOLDINGS A/S	2.23%	1.17M	26.99M	-371.3K	-24.12%
Mar 31, 2024	CORMORANT ASSET MANAGEMENT, LP	3.27%	1.71M	39.55M	0	0
Mar 31, 2024	COMMODORE CAPITAL LP	3.3%	1.73M	39.86M	925K	+115.63%
Mar 31, 2024	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	6.32%	3.3M	76.34M	-600.94K	-15.39%
Mar 31, 2024	VR ADVISER, LLC	6.49%	3.4M	78.47M	0	0
Mar 31, 2024	VIKING GLOBAL INVESTORS LP	6.99%	3.65M	84.43M	-3.61K	-0.10%
Mar 31, 2024	FORESITE CAPITAL MANAGEMENT IV, LLC	7.72%	4.04M	93.34M	0	0
Mar 31, 2024	GENERAL ATLANTIC, L.P.	14.4%	7.53M	174.05M	1.38M	+22.34%
Dec 31, 2023	SPHERA FUNDS MANAGEMENT LTD.	0.6%	245K	6.87M	245K	+100.00%
Dec 31, 2023	FORESITE CAPITAL MANAGEMENT IV, LLC	9.87%	4.04M	113.29M	295.39K	+7.89%
Dec 31, 2023	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	9.54%	3.9M	109.52M	-880.36K	-18.40%
Dec 31, 2023	VIKING GLOBAL INVESTORS LP	8.94%	3.66M	102.58M	425K	+13.15%
Dec 31, 2023	VR ADVISER, LLC	8.3%	3.4M	95.25M	1.83M	+117.18%
Dec 31, 2023	CORMORANT ASSET MANAGEMENT, LP	4.18%	1.71M	48.01M	350K	+25.71%
Dec 31, 2023	NOVO HOLDINGS A/S	3.76%	1.54M	43.18M	210K	+15.80%
Dec 31, 2023	ECOR1 CAPITAL, LLC	2.2%	900K	25.25M	900K	+100.00%
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	2.06%	842.7K	23.64M	842.7K	+100.00%
Dec 31, 2023	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	1.99%	812.24K	22.78M	812.24K	+100.00%
Dec 31, 2023	COMMODORE CAPITAL LP	1.96%	800K	22.44M	800K	+100.00%
Dec 31, 2023	5AM VENTURE MANAGEMENT, LLC	1.95%	797.6K	22.37M	210K	+35.74%
Dec 31, 2023	SOFINNOVA INVESTMENTS, INC.	1.25%	510.44K	14.32M	510.44K	+100.00%
Dec 31, 2023	VIVO CAPITAL, LLC	0.7%	285K	7.99M	285K	+100.00%
Dec 31, 2023	VENBIO PARTNERS LLC	12.03%	4.92M	137.99M	654.83K	+15.35%
Dec 31, 2023	SOLEUS CAPITAL MANAGEMENT, L.P.	0.53%	217.4K	6.1M	-126.58K	-36.80%
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	0.46%	188.52K	5.29M	188.52K	+100.00%
Dec 31, 2023	CITADEL ADVISORS LLC	0.35%	141.46K	3.97M	141.46K	+100.00%
Dec 31, 2023	BLACKSTONE INC.	0.24%	100K	2.81M	100K	+100.00%
Dec 31, 2023	WALLEYE CAPITAL LLC	0.19%	77.87K	2.18M	-3.15K	-3.88%
Dec 31, 2023	HUDSON BAY CAPITAL MANAGEMENT LP	0.17%	70.13K	1.97M	31.24K	+80.33%
Dec 31, 2023	MARSHALL WACE, LLP	0.15%	60.12K	1.69M	60.12K	+100.00%
Dec 31, 2023	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.13%	55.08K	1.54M	55.08K	+100.00%
Dec 31, 2023	QUBE RESEARCH & TECHNOLOGIES LTD	0.08%	32.32K	906.52K	29.74K	+1,153.12%
Dec 31, 2023	MORGAN STANLEY	0.06%	22.49K	630.79K	-11.21K	-33.26%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	0.05%	21.6K	605.74K	0	0
Dec 31, 2023	UBS OCONNOR LLC	0.04%	18K	504.9K	18K	+100.00%
Dec 31, 2023	SCHONFELD STRATEGIC ADVISORS LLC	0.03%	12.4K	347.82K	500	+4.20%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.02%	8.55K	239.8K	8.55K	+100.00%
Dec 31, 2023	TWO SIGMA INVESTMENTS, LP	0.02%	8.2K	229.95K	8.2K	+100.00%
Dec 31, 2023	BLACKROCK INC.	0.01%	2.27K	63.62K	0	0
Dec 31, 2023	QUARRY LP	0%	750	21.04K	750	+100.00%
Dec 31, 2023	JPMORGAN CHASE & CO	0%	190	5.33K	190	+100.00%
Dec 31, 2023	PIPER SANDLER & CO.	0%	181	5.08K	181	+100.00%
Dec 31, 2023	UBS GROUP AG	0%	0	-	-50	-100.00%
Dec 31, 2023	FORESITE CAPITAL MANAGEMENT V, LLC	0%	0	-	-33.14K	-100.00%
Dec 31, 2023	Y-INTERCEPT (HONG KONG) LTD	0%	0	-	-17.55K	-100.00%
Dec 31, 2023	GENERAL ATLANTIC, L.P.	15.05%	6.16M	172.68M	1.75M	+39.72%
Dec 31, 2023	FMR LLC	12.69%	5.19M	145.66M	1.99M	+61.90%
Sep 30, 2023	LYNX1 CAPITAL MANAGEMENT LP	0%	0	-	-21.23K	-100.00%
Sep 30, 2023	SILVERARC CAPITAL MANAGEMENT, LLC	0%	0	-	-200K	-100.00%
Sep 30, 2023	JPMORGAN CHASE & CO	0%	0	-	-151	-100.00%
Sep 30, 2023	UBS GROUP AG	0%	50	1.04K	-1.25K	-96.15%
Sep 30, 2023	BLACKROCK INC.	0.01%	2.27K	47.33K	2.11K	+1,353.85%
Sep 30, 2023	QUBE RESEARCH & TECHNOLOGIES LTD	0.01%	2.58K	53.82K	2.58K	+100.00%
Sep 30, 2023	SCHONFELD STRATEGIC ADVISORS LLC	0.03%	11.9K	248.35K	300	+2.59%
Sep 30, 2023	Y-INTERCEPT (HONG KONG) LTD	0.04%	17.55K	366.33K	17.55K	+100.00%
Sep 30, 2023	GEODE CAPITAL MANAGEMENT, LLC	0.05%	21.6K	450.69K	2.95K	+15.83%
Sep 30, 2023	FORESITE CAPITAL MANAGEMENT V, LLC	0.08%	33.14K	691.67K	-1K	-2.93%
Sep 30, 2023	MORGAN STANLEY	0.08%	33.7K	703.26K	-11.64K	-25.67%
Sep 30, 2023	HUDSON BAY CAPITAL MANAGEMENT LP	0.1%	38.89K	811.7K	38.89K	+100.00%
Sep 30, 2023	WALLEYE CAPITAL LLC	0.2%	81.02K	1.69M	10.69K	+15.20%
Sep 30, 2023	SOLEUS CAPITAL MANAGEMENT, L.P.	0.84%	343.98K	7.18M	-47.93K	-12.23%
Sep 30, 2023	5AM VENTURE MANAGEMENT, LLC	1.44%	587.6K	12.26M	0	0
Sep 30, 2023	NOVO HOLDINGS A/S	3.26%	1.33M	27.74M	0	0
Sep 30, 2023	CORMORANT ASSET MANAGEMENT, LP	3.34%	1.36M	28.41M	387.85K	+39.84%
Sep 30, 2023	VR ADVISER, LLC	3.83%	1.56M	32.63M	237.31K	+17.89%
Sep 30, 2023	FMR LLC	7.86%	3.21M	66.94M	-179.59K	-5.30%
Sep 30, 2023	GENERAL ATLANTIC, L.P.	10.79%	4.41M	91.96M	0	0
Sep 30, 2023	VIKING GLOBAL INVESTORS LP	7.92%	3.23M	67.45M	0	0
Sep 30, 2023	FORESITE CAPITAL MANAGEMENT IV, LLC	9.17%	3.74M	78.13M	0	0
Sep 30, 2023	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	11.72%	4.78M	99.86M	-84.11K	-1.73%
Sep 30, 2023	VENBIO PARTNERS LLC	10.45%	4.26M	89M	0	0

Insiders

Among the PHVS insiders holding of 6.14% of the stake in company, SCHIKAN JOHANNES GERARDUS CHRISTIAAN PETRUS, director, holds the largest shares of 355.17K. MODIG BERNDT, Chief Executive Officer, is the second largest PHVS insider with ownership of 135.21K shares. NASSIF DAVID W., CFO / CLO, stands third with possession of 120.3K shares of that stake.

Insiders	Designation	Shares Held
SCHIKAN JOHANNES GERARDUS CHRISTIAAN PETRUS	director	355.17K
MODIG BERNDT	Chief Executive Officer	135.21K
NASSIF DAVID W.	CFO / CLO	120.3K
LU PENG	Chief Medical Officer	66.08K
LESAGE ANNE	Chief Early Development	56.45K
NIJDAM ANNA	Principal Accounting Officer	46.28K
SOUVERIJNS WIM	Chief Commercial Officer	45.11K
ABELE STEFAN ANDREAS	Chief Technical Ops Officer	35.19K
BJORK ELISABETH	director	15.17K
GLASSMAN ROBERT	director	10.5K
MONGES VIVIANE	director	5.5K

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Jun 15, 2026	MODIG BERNDT	SALE	31.46	100	3.15K	135.21K
Jun 04, 2026	NIJDAM ANNA	SALE	30.87	2.67K	82.43K	46.28K
May 22, 2026	NIJDAM ANNA	SALE	30.74	5.5K	169.08K	48.95K
May 21, 2026	MONGES VIVIANE	SALE	30.29	9.67K	292.85K	5.5K
May 21, 2026	NASSIF DAVID W.	SALE	30.31	10K	303.08K	120.3K
May 21, 2026	NIJDAM ANNA	SALE	30.60	1.83K	55.97K	48.95K
May 20, 2026	BJORK ELISABETH	SALE	29.32	10K	293.17K	15.17K
May 18, 2026	MODIG BERNDT	SALE	29.22	2.29K	66.98K	137.5K
May 15, 2026	GLASSMAN ROBERT	SALE	29.82	4.67K	139.15K	10.5K
May 15, 2026	ABELE STEFAN ANDREAS	SALE	29.82	8.75K	260.86K	35.19K
May 15, 2026	SOUVERIJNS WIM	SALE	29.92	10K	299.16K	45.11K
May 01, 2026	LU PENG	SALE	31.00	143	4.43K	66.08K
Apr 30, 2026	LU PENG	SALE	30.24	15K	453.63K	66.08K
Apr 30, 2026	LESAGE ANNE	SALE	30.26	18K	544.6K	56.45K
Apr 30, 2026	SCHIKAN JOHANNES GERARDUS CHRISTIAAN PETRUS	SALE	31.03	670	20.79K	355.17K
Apr 29, 2026	LU PENG	SALE	30.06	3.73K	112.23K	62.35K
Apr 29, 2026	SCHIKAN JOHANNES GERARDUS CHRISTIAAN PETRUS	SALE	30.07	3.83K	115.17K	384.24K
Apr 29, 2026	LESAGE ANNE	SALE	30.08	3.7K	111.28K	56.45K
Apr 23, 2026	LU PENG	SALE	30.03	100	3K	66.08K
Apr 23, 2026	LESAGE ANNE	SALE	30.03	100	3K	56.45K
Apr 23, 2026	SCHIKAN JOHANNES GERARDUS CHRISTIAAN PETRUS	SALE	30.03	100	3K	388.07K
Apr 22, 2026	SCHIKAN JOHANNES GERARDUS CHRISTIAAN PETRUS	SALE	30.05	7K	210.38K	388.17K
Apr 22, 2026	LU PENG	SALE	30.05	7K	210.4K	66.08K
Apr 22, 2026	LESAGE ANNE	SALE	30.00	500	15K	56.45K
Apr 16, 2026	MODIG BERNDT	SALE	28.60	2.29K	65.56K	139.79K
Apr 09, 2026	MODIG BERNDT	SALE	28.41	200	5.68K	142.08K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES127.84K26

NET SHARES-127.84K26

SHARES HELD3M26

% NET SHARES-104.26%0%

Frequently Asked Questions

Stock Outstanding Shares

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares0.63

Short Percent Of Float0.76

Shares Outstanding64.30M

Shares Float37.11M

Shares Short404.97K

Short Ratio3.54

0.76%

Short % of Float

0.63%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

6.14% Percentage of Shares held by All Insiders

85.23% Percentage of Shares held by All Institutions

90.81% Percentage of Float held by Institutions

146

Number of Institutions Holding Shares

Institutional Ownership

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Mar 31, 2026	SATURN V CAPITAL MANAGEMENT LLC	2.03%	1.2M	33.94M	61.37K	+5.38%
Mar 31, 2026	WELLINGTON MANAGEMENT GROUP LLP	3.58%	2.12M	59.86M	213.11K	+11.18%
Mar 31, 2026	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	4.52%	2.68M	75.58M	-126.57K	-4.52%
Mar 31, 2026	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	5.28%	3.13M	88.31M	0	0
Mar 31, 2026	VIKING GLOBAL INVESTORS LP	6.18%	3.65M	103.21M	0	0
Mar 31, 2026	DAIWA SECURITIES GROUP INC.	0%	0	-	-213	-100.00%
Mar 31, 2026	SBI SECURITIES CO., LTD.	0%	1	28	0	0
Mar 31, 2026	BARE FINANCIAL SERVICES, INC	0%	6	170	6	+100.00%
Mar 31, 2026	CAITONG INTERNATIONAL ASSET MANAGEMENT CO., LTD	0%	18	508	12	+200.00%
Mar 31, 2026	CENTERPOINT ADVISORS, LLC	0%	100	3K	0	0
Mar 31, 2026	WELLS FARGO & COMPANY/MN	0%	450	12.71K	0	0
Mar 31, 2026	BNP PARIBAS ARBITRAGE, SNC	0%	1.39K	39.24K	-57.65K	-97.65%
Mar 31, 2026	GF FUND MANAGEMENT CO. LTD.	0%	1.44K	40.65K	181	+14.39%
Mar 31, 2026	SIMPLEX TRADING, LLC	0%	2.17K	61.39M	2.17K	+100.00%
Mar 31, 2026	QUANTBOT TECHNOLOGIES LP	0%	2.39K	67.55K	-1.87K	-43.87%
Mar 31, 2026	CITIGROUP INC	0%	2.44K	68.99K	655	+36.65%
Mar 31, 2026	MIRAE ASSET GLOBAL INVESTMENTS CO., LTD.	0.01%	3.34K	94.38K	228	+7.32%
Mar 31, 2026	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	0.01%	5.72K	161.7K	214	+3.88%
Mar 31, 2026	KLP KAPITALFORVALTNING AS	0.01%	5.8K	163.85K	0	0
Mar 31, 2026	VANGUARD INVESTMENTS AUSTRALIA, LTD.	0.01%	6.09K	172.01K	6.09K	+100.00%
Mar 31, 2026	PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO	0.01%	7.57K	213.82K	0	0
Mar 31, 2026	PERSISTENT ASSET PARTNERS LTD	0.01%	7.9K	223.29K	7.9K	+100.00%
Mar 31, 2026	TEACHER RETIREMENT SYSTEM OF TEXAS	0.01%	8.18K	230.97K	-735	-8.25%
Mar 31, 2026	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0.01%	8.24K	232.75K	0	0
Mar 31, 2026	VIRTUS INVESTMENT ADVISERS, INC.	0.02%	11.29K	318.83K	275	+2.50%
Mar 31, 2026	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.02%	11.37K	321.12K	929	+8.90%
Mar 31, 2026	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.02%	13.47K	380.53K	13.47K	+100.00%
Mar 31, 2026	VANGUARD ASSET MANAGEMENT, LTD	0.03%	15.06K	425.45K	15.06K	+100.00%
Mar 31, 2026	NUVEEN, LLC	0.03%	17.01K	480.45K	0	0
Mar 31, 2026	JUMP FINANCIAL, LLC	0.03%	19.5K	550.88K	-6.8K	-25.86%
Mar 31, 2026	JPMORGAN CHASE & CO	0.03%	20.01K	545.94K	-1.94K	-8.83%
Mar 31, 2026	PALUMBO WEALTH MANAGEMENT LLC	0.03%	20.61K	582.18K	426	+2.11%
Mar 31, 2026	LEGAL & GENERAL GROUP PLC	0.05%	26.78K	756.42K	4.11K	+18.13%
Mar 31, 2026	HRT FINANCIAL LP	0.05%	27.62K	780K	12.86K	+87.10%
Mar 31, 2026	SWISS NATIONAL BANK	0.08%	44.76K	1.26M	0	0
Mar 31, 2026	MILLENNIUM MANAGEMENT LLC	0.31%	181.95K	5.14M	-66.91K	-26.89%
Mar 31, 2026	JANE STREET GROUP, LLC	0%	0	-	-73.11K	-100.00%
Mar 31, 2026	ALPS ADVISORS INC	0.09%	52.15K	1.47M	-444	-0.84%
Mar 31, 2026	DEUTSCHE BANK AG\	0.09%	53.72K	1.52M	-2.67K	-4.73%
Mar 31, 2026	TD ASSET MANAGEMENT INC	0.09%	54.83K	1.55M	-65.42K	-54.41%
Mar 31, 2026	UBS GROUP AG	0.12%	71.94K	2.03M	-65.79K	-47.77%
Mar 31, 2026	UBS ASSET MANAGEMENT AMERICAS INC	0.13%	77.65K	2.19M	-6.3K	-7.51%
Mar 31, 2026	NORTHERN TRUST CORP	0.14%	83.47K	2.36M	2.43K	+3.00%
Mar 31, 2026	EQT FUND MANAGEMENT S.A R.L.	5.79%	3.42M	96.75M	0	0
Mar 31, 2026		0.28%	167.01K	4.72M	167.01K	+100.00%
Mar 31, 2026	CITADEL ADVISORS LLC	0.28%	168.63K	4.76M	33.56K	+24.85%
Mar 31, 2026	FORESITE CAPITAL MANAGEMENT V, LLC	0.33%	194.13K	5.48M	194.13K	+100.00%
Mar 31, 2026	ORBIMED ADVISORS LLC	0.35%	205.4K	5.8M	0	0
Mar 31, 2026	D. E. SHAW & CO., INC.	0.54%	321.16K	9.07M	60.59K	+23.25%
Mar 31, 2026	BOOTHBAY FUND MANAGEMENT, LLC	0.27%	157.12K	4.44M	0	0
Mar 31, 2026	TFG ASSET MANAGEMENT GP LTD	0.37%	221.61K	6.26M	27K	+13.87%
Mar 31, 2026	BLACKROCK, INC.	1.28%	757.21K	21.39M	48.66K	+6.87%
Mar 31, 2026	NOVO HOLDINGS A/S	2.96%	1.75M	49.44M	0	0
Mar 31, 2026	COMMODORE CAPITAL LP	3.24%	1.92M	54.21M	29.53K	+1.56%
Mar 31, 2026	VENBIO PARTNERS LLC	7.84%	4.64M	131.06M	0	0
Mar 31, 2026	ALYESKA INVESTMENT GROUP, L.P.	0.21%	125K	3.53M	0	0
Mar 31, 2026	TWO SIGMA INVESTMENTS, LP	0.21%	126.08K	3.56M	-89.11K	-41.41%
Mar 31, 2026	STATE STREET CORP	0.26%	152.95K	4.32M	-8.55K	-5.30%
Mar 31, 2026	SCHRODER INVESTMENT MANAGEMENT GROUP	0.27%	158.02K	4.31M	0	0
Mar 31, 2026	MORGAN STANLEY	0.28%	164.32K	4.64M	-84.01K	-33.83%
Mar 31, 2026	OCTAGON CAPITAL ADVISORS LP	0.28%	165K	4.66M	-506.47K	-75.43%
Mar 31, 2026	PRICE T ROWE ASSOCIATES INC /MD/	0.75%	442.26K	12.49M	-499.35K	-53.03%
Mar 31, 2026	BALYASNY ASSET MANAGEMENT L.P.	0.78%	462.25K	13.06M	-34.01K	-6.85%
Mar 31, 2026	DV TRADING LLC	0.24%	143.97K	4.07M	143.97K	+100.00%
Mar 31, 2026	KYNAM CAPITAL MANAGEMENT, LP	1.08%	640.4K	18.09M	0	0
Mar 31, 2026	ROCK SPRINGS CAPITAL MANAGEMENT LP	1.09%	645.53K	18.24M	22.13K	+3.55%
Mar 31, 2026	SOLEUS CAPITAL MANAGEMENT, L.P.	1.19%	702.05K	19.83M	0	0
Mar 31, 2026	POLAR CAPITAL HOLDINGS PLC	1.32%	781.02K	22.06M	543.05K	+228.21%
Mar 31, 2026	5AM VENTURE MANAGEMENT, LLC	1.35%	797.6K	22.53M	0	0
Mar 31, 2026	SOFINNOVA INVESTMENTS, INC.	1.38%	818.33K	23.12M	73.16K	+9.82%
Mar 31, 2026	CORMORANT ASSET MANAGEMENT, LP	1.69%	1M	28.25M	-83K	-7.66%
Mar 31, 2026	IKARIAN CAPITAL, LLC	0.82%	486.86K	13.75M	0	0
Mar 31, 2026	PATIENT SQUARE CAPITAL LP	0.83%	493K	13.93M	-49.7K	-9.16%
Mar 31, 2026	POINT72 ASSET MANAGEMENT, L.P.	1.7%	1.01M	28.45M	295.39K	+41.51%
Mar 31, 2026	SQUAREPOINT OPS LLC	0.16%	96.38K	2.72M	-3.98K	-3.96%
Mar 31, 2026	BAKER BROS. ADVISORS LP	0.63%	375K	10.59M	0	0
Mar 31, 2026	EVERSEPT PARTNERS, LP	0.69%	406.96K	11.5M	-32.22K	-7.34%
Mar 31, 2026	FORESITE CAPITAL MANAGEMENT IV, LLC	8.08%	4.78M	134.99M	0	0
Mar 31, 2026	FMR LLC	10.62%	6.28M	177.54M	-114.69K	-1.79%
Mar 31, 2026	GEODE CAPITAL MANAGEMENT, LLC	0.15%	89.13K	2.52M	2.33K	+2.68%
Mar 31, 2026	HIGHVISTA STRATEGIES LLC	0.17%	97.87K	2.76M	-64.5K	-39.73%
Mar 31, 2026	ADAR1 CAPITAL MANAGEMENT, LLC	0.18%	105.53K	2.98M	20K	+23.38%
Mar 31, 2026	GENERAL ATLANTIC, L.P.	13.58%	8.03M	226.88M	0	0
Mar 31, 2026	STEMPOINT CAPITAL LP	0.15%	86.64K	2.45M	28.25K	+48.38%
Mar 31, 2026	GOLDMAN SACHS GROUP INC	0.24%	142.93K	4.04M	-17.98K	-11.17%
Dec 31, 2025	CITADEL ADVISORS LLC	0.22%	135.07K	3.75M	5.33K	+4.11%
Dec 31, 2025	TWO SIGMA INVESTMENTS, LP	0.35%	215.19K	5.97M	204.58K	+1,928.74%
Dec 31, 2025	MILLENNIUM MANAGEMENT LLC	0.4%	248.86K	6.91M	142.31K	+133.56%
Dec 31, 2025	HRT FINANCIAL LP	0.02%	14.76K	409K	-11.44K	-43.65%
Dec 31, 2025	ROYAL BANK OF CANADA	0%	80	2K	4	+5.26%
Dec 31, 2025	DAIWA SECURITIES GROUP INC.	0%	213	6K	213	+100.00%
Dec 31, 2025	WELLS FARGO & COMPANY/MN	0%	450	12.49K	450	+100.00%
Dec 31, 2025	GF FUND MANAGEMENT CO. LTD.	0%	1.26K	34.91K	1.26K	+100.00%
Dec 31, 2025	CITIGROUP INC	0%	1.79K	49.59K	1.22K	+216.84%
Dec 31, 2025	BARCLAYS PLC	0%	2.78K	77.01K	2.78K	+100.00%
Dec 31, 2025	MIRAE ASSET GLOBAL INVESTMENTS CO., LTD.	0.01%	3.11K	86.39K	3.11K	+100.00%
Dec 31, 2025	ZURCHER KANTONALBANK (ZURICH CANTONALBANK)	0.01%	3.98K	110.42K	3.98K	+100.00%
Dec 31, 2025	PALUMBO WEALTH MANAGEMENT LLC	0.03%	20.18K	560.05K	3.54K	+21.28%
Dec 31, 2025		0.32%	198.77K	5.52M	198.77K	+100.00%
Dec 31, 2025	JPMORGAN CHASE & CO	0.04%	21.94K	608.89K	-5.14K	-18.99%
Dec 31, 2025	LEGAL & GENERAL GROUP PLC	0.04%	22.67K	628.98K	0	0
Dec 31, 2025	JUMP FINANCIAL, LLC	0.04%	26.3K	729.83K	26.3K	+100.00%
Dec 31, 2025	BIRCHVIEW CAPITAL, LP	0.05%	29.85K	828.25K	15K	+101.03%
Dec 31, 2025	MARSHALL WACE, LLP	0.05%	31.83K	883.34K	4.74K	+17.48%
Dec 31, 2025	TUDOR INVESTMENT CORP ET AL	0.05%	32.03K	888.78K	-45.86K	-58.88%
Dec 31, 2025	SWISS NATIONAL BANK	0.07%	44.76K	1.24M	2.4K	+5.67%
Dec 31, 2025	ALPS ADVISORS INC	0.08%	52.59K	1.46M	52.59K	+100.00%
Dec 31, 2025	DEUTSCHE BANK AG\	0.09%	56.39K	1.56M	4.58K	+8.85%
Dec 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.09%	59.04K	1.64M	58.62K	+14,194.67%
Dec 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.1%	60.1K	1.67M	60.1K	+100.00%
Dec 31, 2025	TFG ASSET MANAGEMENT GP LTD	0.31%	194.61K	5.4M	0	0
Dec 31, 2025	VENBIO PARTNERS LLC	7.45%	4.64M	128.74M	0	0
Dec 31, 2025	TD ASSET MANAGEMENT INC	0.19%	120.25K	3.34M	15.89K	+15.23%
Dec 31, 2025	ALYESKA INVESTMENT GROUP, L.P.	0.2%	125K	3.47M	0	0
Dec 31, 2025	UBS GROUP AG	0.22%	137.73K	3.82M	6.98K	+5.34%
Dec 31, 2025	BAKER BROS. ADVISORS LP	0.6%	375K	10.41M	0	0
Dec 31, 2025	EVERSEPT PARTNERS, LP	0.71%	439.18K	12.19M	439.18K	+100.00%
Dec 31, 2025	IKARIAN CAPITAL, LLC	0.78%	486.86K	13.51M	276.69K	+131.65%
Dec 31, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	0.14%	85.53K	2.37M	51.4K	+150.64%
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.14%	86.8K	2.41M	8.26K	+10.52%
Dec 31, 2025	SQUAREPOINT OPS LLC	0.16%	100.36K	2.78M	100.36K	+100.00%
Dec 31, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.25%	157.12K	4.36M	21.94K	+16.23%
Dec 31, 2025	SCHRODER INVESTMENT MANAGEMENT GROUP	0.25%	158.02K	4.15M	145.95K	+1,208.86%
Dec 31, 2025	HIGHVISTA STRATEGIES LLC	0.26%	162.37K	4.51M	162.37K	+100.00%
Dec 31, 2025	ORBIMED ADVISORS LLC	0.33%	205.4K	5.7M	205.4K	+100.00%
Dec 31, 2025	POLAR CAPITAL HOLDINGS PLC	0.38%	237.96K	6.6M	-26.73K	-10.10%
Dec 31, 2025	D. E. SHAW & CO., INC.	0.42%	260.57K	7.23M	237.69K	+1,038.57%
Dec 31, 2025	BALYASNY ASSET MANAGEMENT L.P.	0.8%	496.26K	13.77M	-129.5K	-20.69%
Dec 31, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	1%	623.4K	17.3M	0	0
Dec 31, 2025	KYNAM CAPITAL MANAGEMENT, LP	1.03%	640.4K	17.77M	-34.61K	-5.13%
Dec 31, 2025	OCTAGON CAPITAL ADVISORS LP	1.08%	671.47K	18.63M	-51.13K	-7.08%
Dec 31, 2025	POINT72 ASSET MANAGEMENT, L.P.	1.14%	711.63K	19.75M	192.24K	+37.01%
Dec 31, 2025	5AM VENTURE MANAGEMENT, LLC	1.28%	797.6K	22.13M	0	0
Dec 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.51%	941.61K	26.13M	124.8K	+15.28%
Dec 31, 2025	CORMORANT ASSET MANAGEMENT, LP	1.74%	1.08M	30.05M	-280.2K	-20.55%
Dec 31, 2025	SATURN V CAPITAL MANAGEMENT LLC	1.83%	1.14M	31.64M	253.7K	+28.62%
Dec 31, 2025	NOVO HOLDINGS A/S	2.81%	1.75M	48.56M	0	0
Dec 31, 2025	COMMODORE CAPITAL LP	3.04%	1.89M	52.43M	-529.03K	-21.87%
Dec 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	3.06%	1.91M	52.89M	171.05K	+9.86%
Dec 31, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	4.5%	2.8M	77.76M	-379.19K	-11.92%
Dec 31, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	5.02%	3.13M	86.75M	683.58K	+27.99%
Dec 31, 2025	VIKING GLOBAL INVESTORS LP	5.87%	3.65M	101.38M	0	0
Dec 31, 2025	FORESITE CAPITAL MANAGEMENT IV, LLC	7.68%	4.78M	132.61M	0	0
Dec 31, 2025	FMR LLC	10.28%	6.4M	177.58M	0	0
Dec 31, 2025	GENERAL ATLANTIC, L.P.	12.9%	8.03M	222.87M	0	0
Dec 31, 2025	QUARRY LP	0%	0	-	-442	-100.00%
Dec 31, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0%	0	-	-183.9K	-100.00%
Dec 31, 2025	SBI SECURITIES CO., LTD.	0%	1	28	-2	-66.67%
Dec 31, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.13%	79.89K	2.1M	20.1K	+33.62%
Dec 31, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.13%	83.95K	2.33M	83.95K	+100.00%
Dec 31, 2025	GOLDMAN SACHS GROUP INC	0.26%	160.91K	4.47M	146.43K	+1,011.56%
Dec 31, 2025	STATE STREET CORP	0.26%	161.5K	4.48M	18.72K	+13.11%
Dec 31, 2025	MORGAN STANLEY	0.4%	248.33K	6.89M	190.07K	+326.23%
Dec 31, 2025	PATIENT SQUARE CAPITAL LP	0.87%	542.7K	15.06M	197.32K	+57.13%
Dec 31, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	1.13%	702.05K	19.48M	55K	+8.50%
Dec 31, 2025	BLACKROCK, INC.	1.14%	708.56K	19.66M	294.14K	+70.98%
Dec 31, 2025	SOFINNOVA INVESTMENTS, INC.	1.2%	745.17K	20.68M	5.29K	+0.72%
Dec 31, 2025	EQT FUND MANAGEMENT S.A R.L.	5.5%	3.42M	95.03M	0	0
Dec 31, 2025	QUANTBOT TECHNOLOGIES LP	0.01%	4.26K	118.22K	4.26K	+100.00%
Dec 31, 2025	NANO CAP NEW MILLENNIUM GROWTH FUND L P	0.01%	5K	138.75M	5K	+100.00%
Dec 31, 2025	KLP KAPITALFORVALTNING AS	0.01%	5.8K	160.95K	0	0
Dec 31, 2025	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0.01%	8.24K	228.63K	2.75K	+50.10%
Dec 31, 2025	TEACHER RETIREMENT SYSTEM OF TEXAS	0.01%	8.91K	247.28K	8.91K	+100.00%
Dec 31, 2025	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.02%	10.44K	289.66K	7.44K	+247.93%
Dec 31, 2025	VIRTUS INVESTMENT ADVISERS, INC.	0.02%	11.01K	305.56K	4.41K	+66.73%
Dec 31, 2025	JANE STREET GROUP, LLC	0.02%	12.6K	349.65M	12.6K	+100.00%
Dec 31, 2025	NUVEEN, LLC	0.03%	17.01K	471.94K	0	0
Dec 31, 2025	VERITION FUND MANAGEMENT LLC	0.03%	17.9K	496.67K	17.9K	+100.00%
Dec 31, 2025	XTX TOPCO LTD	0.03%	18.57K	515.26K	10.36K	+126.08%
Dec 31, 2025	VANGUARD GROUP INC	0.03%	19.31K	535.85M	0	0
Dec 31, 2025	BANK OF AMERICA CORP /DE/	0.03%	19.56K	542.71M	901	+4.83%
Dec 31, 2025	TWO SIGMA ADVISERS, LP	0.14%	89.6K	2.49M	89.6K	+100.00%
Dec 31, 2025	LOGOS GLOBAL MANAGEMENT LP	0.16%	100K	2.78M	-50K	-33.33%
Sep 30, 2025	DEUTSCHE BANK AG\	0.08%	51.81K	1.29M	23.62K	+83.80%
Sep 30, 2025	FORESITE CAPITAL MANAGEMENT IV, LLC	7.68%	4.78M	119.23M	368K	+8.34%
Sep 30, 2025	AMUNDI	0.08%	41.52K	965.27K	14.1K	+51.43%
Sep 30, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	0.06%	34.12K	851.39K	0	0
Sep 30, 2025	VENBIO PARTNERS LLC	7.45%	4.64M	115.75M	350K	+8.16%
Sep 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.31%	816.81K	20.38M	49.49K	+6.45%
Sep 30, 2025	STATE STREET CORP	0.23%	142.78K	3.56M	49.1K	+52.42%
Sep 30, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.22%	135.18K	3.37M	118.99K	+735.12%
Sep 30, 2025	UBS GROUP AG	0.21%	130.75K	3.26M	127.01K	+3,393.24%
Sep 30, 2025	CITADEL ADVISORS LLC	0.21%	129.74K	3.24M	100.52K	+343.99%
Sep 30, 2025	ALYESKA INVESTMENT GROUP, L.P.	0.2%	125K	3.12M	125K	+100.00%
Sep 30, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.19%	119.41K	2.98M	-190.53K	-61.47%
Sep 30, 2025	GENERAL ATLANTIC, L.P.	12.9%	8.03M	200.38M	500K	+6.64%
Sep 30, 2025	FMR LLC	10.28%	6.4M	159.66M	976.77K	+18.01%
Sep 30, 2025	BLACKROCK, INC.	0.67%	414.42K	10.34M	213.33K	+106.09%
Sep 30, 2025	MARSHALL WACE, LLP	0.05%	27.1K	676.05K	27.1K	+100.00%
Sep 30, 2025	JPMORGAN CHASE & CO	0.05%	27.09K	675.77K	23.74K	+710.44%
Sep 30, 2025	LEGAL & GENERAL GROUP PLC	0.04%	22.67K	565.52K	11.12K	+96.24%
Sep 30, 2025	VANGUARD GROUP INC	0.04%	19.31K	481.79K	19.31K	+100.00%
Sep 30, 2025	NUVEEN, LLC	0.03%	17.01K	424.33K	17.01K	+100.00%
Sep 30, 2025	PALUMBO WEALTH MANAGEMENT LLC	0.03%	16.64K	415.19K	2.09K	+14.38%
Sep 30, 2025	BIRCHVIEW CAPITAL, LP	0.03%	14.85K	370.43K	14.85K	+100.00%
Sep 30, 2025	SCHRODER INVESTMENT MANAGEMENT GROUP	0.02%	12.07K	292.89K	12.07K	+100.00%
Sep 30, 2025	KLP KAPITALFORVALTNING AS	0.01%	5.8K	144.71K	0	0
Sep 30, 2025	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0.01%	5.49K	136.95K	3.12K	+131.70%
Sep 30, 2025	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	0.01%	3.26K	81K	0	0
Sep 30, 2025	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.01%	3K	74.85K	3K	+100.00%
Sep 30, 2025	CITIGROUP INC	0%	564	14.07K	7	+1.26%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0%	413	10.3K	54	+15.04%
Sep 30, 2025	CENTERPOINT ADVISORS, LLC	0%	100	2K	0	0
Sep 30, 2025	SBI SECURITIES CO., LTD.	0%	3	75	2	+200.00%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0%	0	-	-1K	-100.00%
Sep 30, 2025	BARCLAYS PLC	0%	0	-	-2.8K	-100.00%
Sep 30, 2025	ALPS ADVISORS INC	0%	0	-	-29.4K	-100.00%
Sep 30, 2025	ROSALIND ADVISORS, INC.	0%	0	-	-223.63K	-100.00%
Sep 30, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	3.92%	2.44M	60.94M	425K	+21.07%
Sep 30, 2025	PARADIGM BIOCAPITAL ADVISORS LP	2.95%	1.84M	45.8M	772.58K	+72.69%
Sep 30, 2025	OCTAGON CAPITAL ADVISORS LP	1.16%	722.6K	18.03M	50K	+7.43%
Sep 30, 2025	KYNAM CAPITAL MANAGEMENT, LP	1.08%	675K	16.84M	675K	+100.00%
Sep 30, 2025	VR ADVISER, LLC	1.08%	674.6K	16.83M	-1.37M	-67.05%
Sep 30, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	1.04%	647.05K	16.14M	-85.92K	-11.72%
Sep 30, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	1%	623.4K	15.55M	0	0
Sep 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.83%	519.38K	12.96M	481.77K	+1,280.89%
Sep 30, 2025	VIKING GLOBAL INVESTORS LP	5.87%	3.65M	91.15M	0	0
Sep 30, 2025	EQT FUND MANAGEMENT S.A R.L.	5.5%	3.42M	85.44M	3.42M	+100.00%
Sep 30, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	5.11%	3.18M	79.37M	-122.11K	-3.70%
Sep 30, 2025	NOVO HOLDINGS A/S	2.81%	1.75M	43.66M	25K	+1.45%
Sep 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	2.79%	1.73M	43.28M	1.73M	+100.00%
Sep 30, 2025	CORMORANT ASSET MANAGEMENT, LP	2.19%	1.36M	34.01M	-91.46K	-6.29%
Sep 30, 2025	5AM VENTURE MANAGEMENT, LLC	1.28%	797.6K	19.9M	0	0
Sep 30, 2025	TUDOR INVESTMENT CORP ET AL	0.14%	77.89K	1.94M	77.89K	+100.00%
Sep 30, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.1%	59.79K	1.49M	10.93K	+22.38%
Sep 30, 2025	COMMODORE CAPITAL LP	3.88%	2.42M	60.34M	507.04K	+26.53%
Sep 30, 2025	BAKER BROS. ADVISORS LP	0.6%	375K	9.36M	375K	+100.00%
Sep 30, 2025	PATIENT SQUARE CAPITAL LP	0.55%	345.38K	8.62M	101.1K	+41.39%
Sep 30, 2025	POLAR CAPITAL HOLDINGS PLC	0.43%	264.69K	6.6M	264.69K	+100.00%
Sep 30, 2025	IKARIAN CAPITAL, LLC	0.34%	210.17K	5.24M	210.17K	+100.00%
Sep 30, 2025	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.32%	200K	4.99M	200K	+100.00%
Sep 30, 2025	TFG ASSET MANAGEMENT GP LTD	0.31%	194.61K	4.86M	6.51K	+3.46%
Sep 30, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.3%	183.9K	4.59M	183.9K	+100.00%
Sep 30, 2025	GREAT POINT PARTNERS LLC	0.25%	155.11K	3.87M	155.11K	+100.00%
Sep 30, 2025	LOGOS GLOBAL MANAGEMENT LP	0.24%	150K	3.74M	150K	+100.00%
Sep 30, 2025	MILLENNIUM MANAGEMENT LLC	0.17%	106.55K	2.66M	93.26K	+702.02%
Sep 30, 2025	TD ASSET MANAGEMENT INC	0.17%	104.36K	2.6M	4.85K	+4.87%
Sep 30, 2025	WOODLINE PARTNERS LP	0.16%	100K	2.5M	100K	+100.00%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.13%	78.54K	1.96M	24.44K	+45.17%
Sep 30, 2025	NORTHERN TRUST CORP	0.13%	77.96K	1.94M	-17.31K	-18.17%
Sep 30, 2025	MORGAN STANLEY	0.09%	58.26K	1.45M	-1.51K	-2.52%
Sep 30, 2025	SWISS NATIONAL BANK	0.07%	42.36K	1.06M	16.1K	+61.32%
Sep 30, 2025	SATURN V CAPITAL MANAGEMENT LLC	1.42%	886.33K	22.11M	886.33K	+100.00%
Sep 30, 2025	SOFINNOVA INVESTMENTS, INC.	1.19%	739.88K	18.46M	154.34K	+26.36%
Sep 30, 2025	BALYASNY ASSET MANAGEMENT L.P.	1.01%	625.76K	15.61M	625.76K	+100.00%
Jun 30, 2025	VENBIO PARTNERS LLC	7.87%	4.29M	75.49M	0	0
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0.03%	16.02K	282.01K	-13.18K	-45.14%
Jun 30, 2025	TFG ASSET MANAGEMENT GP LTD	0.35%	188.1K	3.31M	61.11K	+48.12%
Jun 30, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.57%	309.93K	5.45M	-73.93K	-19.26%
Jun 30, 2025	SOFINNOVA INVESTMENTS, INC.	1.07%	585.53K	10.31M	-7.87K	-1.33%
Jun 30, 2025	UBS GROUP AG	0.01%	3.74K	65.88K	-3.71K	-49.75%
Jun 30, 2025	COMMODORE CAPITAL LP	3.51%	1.91M	33.64M	0	0
Jun 30, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	3.7%	2.02M	35.51M	0	0
Jun 30, 2025	JPMORGAN CHASE & CO	0.01%	3.34K	58.82K	783	+30.60%
Jun 30, 2025	PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO	0.01%	4.5K	79.2K	0	0
Jun 30, 2025	VIRTUS INVESTMENT ADVISERS, INC.	0.01%	5.46K	96.04K	-3.18K	-36.81%
Jun 30, 2025	CENTERPOINT ADVISORS, LLC	0%	100	2K	100	+100.00%
Jun 30, 2025	VANGUARD GROUP INC	0%	0	-	-12.74K	-100.00%
Jun 30, 2025	CORMORANT ASSET MANAGEMENT, LP	2.67%	1.45M	25.6M	-11.8K	-0.80%
Jun 30, 2025	HIGHVISTA STRATEGIES LLC	0.04%	23.74K	417.81K	971	+4.26%
Jun 30, 2025	SWISS NATIONAL BANK	0.05%	26.26K	462.12K	0	0
Jun 30, 2025	DEUTSCHE BANK AG\	0.05%	28.19K	496.07K	12	+0.04%
Jun 30, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	0.06%	34.12K	600.58K	34.12K	+100.00%
Jun 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.07%	37.61K	661.97K	-14.96K	-28.46%
Jun 30, 2025	TD ASSET MANAGEMENT INC	0.18%	99.51K	1.75M	21.39K	+27.38%
Jun 30, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	1.14%	623.4K	10.97M	0	0
Jun 30, 2025	VR ADVISER, LLC	3.76%	2.05M	36.04M	-1.07M	-34.22%
Jun 30, 2025	FORESITE CAPITAL MANAGEMENT IV, LLC	8.09%	4.41M	77.63M	0	0
Jun 30, 2025	CUBIST SYSTEMATIC STRATEGIES, LLC	0%	2.56K	45.07K	283	+12.42%
Jun 30, 2025	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0.03%	14.05K	247.25M	1.26K	+9.83%
Jun 30, 2025	POINT72 ASIA (SINGAPORE) PTE. LTD.	0%	369	6.49K	369	+100.00%
Jun 30, 2025		0%	2.37K	41.69K	0	0
Jun 30, 2025	ALPS ADVISORS INC	0.05%	29.4K	517.41K	-7.24K	-19.75%
Jun 30, 2025	BLACKROCK, INC.	0.37%	201.09K	3.54M	8.22K	+4.26%
Jun 30, 2025	NOVO HOLDINGS A/S	3.16%	1.73M	30.36M	0	0
Jun 30, 2025	FMR LLC	9.95%	5.42M	95.43M	27.02K	+0.50%
Jun 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0%	359	6.32M	201	+127.22%
Jun 30, 2025	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	0.01%	3.26K	57K	3.26K	+100.00%
Jun 30, 2025	LEGAL & GENERAL GROUP PLC	0.02%	11.55K	203.28K	1.7K	+17.20%
Jun 30, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.09%	48.86K	859.88K	7.88K	+19.23%
Jun 30, 2025	PARADIGM BIOCAPITAL ADVISORS LP	1.95%	1.06M	18.71M	1.06M	+100.00%
Jun 30, 2025	GENERAL ATLANTIC, L.P.	13.81%	7.53M	132.55M	0	0
Jun 30, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.03%	16.19K	284.89K	16.19K	+100.00%
Jun 30, 2025	MORGAN STANLEY	0.11%	59.77K	1.05B	-15.59K	-20.69%
Jun 30, 2025	ROSALIND ADVISORS, INC.	0.41%	223.63K	3.94M	0	0
Jun 30, 2025	PATIENT SQUARE CAPITAL LP	0.45%	244.28K	4.3M	-1.21K	-0.49%
Jun 30, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	6.06%	3.3M	58.14M	0	0
Jun 30, 2025	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0%	2.37K	41.69K	0	0
Jun 30, 2025	KLP KAPITALFORVALTNING AS	0.01%	5.8K	102.08K	0	0
Jun 30, 2025	CITADEL ADVISORS LLC	0.05%	29.22K	514.29M	29.22K	+100.00%
Jun 30, 2025	OCTAGON CAPITAL ADVISORS LP	1.23%	672.6K	11.84M	-97.22K	-12.63%
Jun 30, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	1.34%	732.97K	12.9M	-81.68K	-10.03%
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.41%	767.32K	13.51M	181.23K	+30.92%
Jun 30, 2025	5AM VENTURE MANAGEMENT, LLC	1.46%	797.6K	14.04M	0	0
Jun 30, 2025	BARCLAYS PLC	0.01%	2.8K	49K	-65	-2.27%
Jun 30, 2025	ROYAL BANK OF CANADA	0%	58	1K	58	+100.00%
Jun 30, 2025	VIKING GLOBAL INVESTORS LP	6.7%	3.65M	64.3M	0	0
Jun 30, 2025	MILLENNIUM MANAGEMENT LLC	0.02%	13.29K	233.82K	13.29K	+100.00%
Jun 30, 2025	PALUMBO WEALTH MANAGEMENT LLC	0.03%	14.55K	256.06K	447	+3.17%
Jun 30, 2025	AMUNDI	0.05%	27.42K	488.57K	27.42K	+2,741,600.00%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.1%	54.1K	951.94K	15.77K	+41.14%
Jun 30, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.1%	55.38K	974.64K	-12.95K	-18.96%
Jun 30, 2025	STATE STREET CORP	0.17%	93.67K	1.65M	-111	-0.12%
Jun 30, 2025	NORTHERN TRUST CORP	0.17%	95.27K	1.68M	8.39K	+9.66%
Mar 31, 2025		0%	2.37K	37.19K	0	0
Mar 31, 2025	DEUTSCHE BANK AG\	0.05%	28.17K	442.33K	10.01K	+55.07%
Mar 31, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.1%	52.57K	825.41K	44.65K	+563.73%
Mar 31, 2025	MORGAN STANLEY	0.14%	75.37K	1.18M	48.37K	+179.16%
Mar 31, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.71%	383.86K	6.03M	-4.33K	-1.11%
Mar 31, 2025	GENERAL ATLANTIC, L.P.	13.93%	7.53M	118.24M	0	0
Mar 31, 2025	PALUMBO WEALTH MANAGEMENT LLC	0.03%	14.1K	221.4K	3.88K	+37.97%
Mar 31, 2025	PATIENT SQUARE CAPITAL LP	0.45%	245.5K	3.85M	37.89K	+18.25%
Mar 31, 2025	VIRTUS INVESTMENT ADVISERS, INC.	0.02%	8.64K	135.59K	8.64K	+100.00%
Mar 31, 2025	LEGAL & GENERAL GROUP PLC	0.02%	9.86K	154.72K	0	0
Mar 31, 2025	TFG ASSET MANAGEMENT GP LTD	0.23%	127K	1.99M	127K	+100.00%
Mar 31, 2025	BLACKROCK, INC.	0.36%	192.87K	3.03M	-1.33K	-0.68%
Mar 31, 2025	PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO	0.01%	4.5K	70.65K	1K	+28.57%
Mar 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0%	158	2.48K	58	+58.00%
Mar 31, 2025	CITIGROUP INC	0%	543	8.53K	0	0
Mar 31, 2025	WELLS FARGO & COMPANY/MN	0%	950	14.92K	150	+18.75%
Mar 31, 2025	VANGUARD GROUP INC	0.02%	12.74K	200.02K	0	0
Mar 31, 2025	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0.02%	12.79K	200.82K	-635	-4.73%
Mar 31, 2025	SWISS NATIONAL BANK	0.05%	26.26K	412.24K	0	0
Mar 31, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.08%	40.98K	643.36K	0	0
Mar 31, 2025	TD ASSET MANAGEMENT INC	0.14%	78.12K	1.23M	22.91K	+41.48%
Mar 31, 2025	ROSALIND ADVISORS, INC.	0.41%	223.63K	3.51M	223.63K	+100.00%
Mar 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.08%	586.09K	9.2M	142.19K	+32.03%
Mar 31, 2025	SOFINNOVA INVESTMENTS, INC.	1.1%	593.4K	9.32M	32.68K	+5.83%
Mar 31, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	1.15%	623.4K	9.79M	-151.73K	-19.57%
Mar 31, 2025	OCTAGON CAPITAL ADVISORS LP	1.42%	769.82K	12.09M	-8.19K	-1.05%
Mar 31, 2025	5AM VENTURE MANAGEMENT, LLC	1.48%	797.6K	12.52M	0	0
Mar 31, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	1.51%	814.65K	12.79M	0	0
Mar 31, 2025	CORMORANT ASSET MANAGEMENT, LP	2.71%	1.47M	23.02M	0	0
Mar 31, 2025	NOVO HOLDINGS A/S	3.19%	1.73M	27.08M	0	0
Mar 31, 2025	COMMODORE CAPITAL LP	3.54%	1.91M	30.01M	0	0
Mar 31, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	3.73%	2.02M	31.67M	0	0
Mar 31, 2025	VR ADVISER, LLC	5.76%	3.11M	48.87M	-107.41K	-3.34%
Mar 31, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	6.11%	3.3M	51.86M	0	0
Mar 31, 2025	VIKING GLOBAL INVESTORS LP	6.76%	3.65M	57.36M	0	0
Mar 31, 2025	VENBIO PARTNERS LLC	7.93%	4.29M	67.34M	0	0
Mar 31, 2025	FORESITE CAPITAL MANAGEMENT IV, LLC	8.16%	4.41M	69.25M	12.7K	+0.29%
Mar 31, 2025	FMR LLC	9.98%	5.4M	84.71M	0	0
Mar 31, 2025	JPMORGAN CHASE & CO	0%	2.56K	40.18K	-541	-17.45%
Mar 31, 2025	HIGHVISTA STRATEGIES LLC	0.04%	22.77K	357.46K	0	0
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0.05%	29.21K	458.53K	-1.6K	-5.20%
Mar 31, 2025	ALPS ADVISORS INC	0.07%	36.63K	575.14K	-7.04K	-16.12%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.07%	38.33K	601.83K	0	0
Mar 31, 2025	CUBIST SYSTEMATIC STRATEGIES, LLC	0%	2.28K	35.76K	-1.06K	-31.71%
Mar 31, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.13%	68.33K	1.07M	4.6K	+7.21%
Mar 31, 2025	UBS GROUP AG	0.01%	7.45K	116.95K	6.4K	+612.82%
Mar 31, 2025	STATE STREET CORP	0.17%	93.78K	1.47M	1.78K	+1.93%
Mar 31, 2025	NORTHERN TRUST CORP	0.16%	86.88K	1.36M	-5.06K	-5.50%
Mar 31, 2025	BARCLAYS PLC	0.01%	2.86K	45K	-3	-0.10%
Mar 31, 2024	VENBIO PARTNERS LLC	8.2%	4.29M	99.13M	-630.2K	-12.81%
Mar 31, 2024	QUARRY LP	0%	0	-	-750	-100.00%
Mar 31, 2024	VIVO CAPITAL, LLC	0%	0	-	-285K	-100.00%
Mar 31, 2024	SCHONFELD STRATEGIC ADVISORS LLC	0%	0	-	-12.4K	-100.00%
Mar 31, 2024	BLACKSTONE INC.	0%	0	-	-100K	-100.00%
Mar 31, 2024	TWO SIGMA INVESTMENTS, LP	0%	0	-	-8.2K	-100.00%
Mar 31, 2024	UBS OCONNOR LLC	0%	0	-	-18K	-100.00%
Mar 31, 2024	PIPER SANDLER & CO.	0%	0	-	-181	-100.00%
Mar 31, 2024	ADAR1 CAPITAL MANAGEMENT, LLC	0%	2K	46.22K	2K	+100.00%
Mar 31, 2024	BLACKROCK INC.	0%	2.27K	52.41K	0	0
Mar 31, 2024	JPMORGAN CHASE & CO	0.01%	3.15K	72.8K	2.96K	+1,557.89%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.01%	7.81K	180.44K	7.81K	+100.00%
Mar 31, 2024	JUMP FINANCIAL, LLC	0.02%	11.7K	270.39K	11.7K	+100.00%
Mar 31, 2024	HIGHVISTA STRATEGIES LLC	0.03%	16.75K	387.09K	16.75K	+100.00%
Mar 31, 2024	HUDSON BAY CAPITAL MANAGEMENT LP	0.04%	20.02K	462.62K	-50.12K	-71.46%
Mar 31, 2024	MILLENNIUM MANAGEMENT LLC	0.04%	20.53K	474.38K	-167.99K	-89.11%
Mar 31, 2024	MORGAN STANLEY	0.06%	29.04K	671.14K	6.55K	+29.14%
Mar 31, 2024	QUBE RESEARCH & TECHNOLOGIES LTD	0.06%	30.14K	696.49K	-2.18K	-6.75%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.06%	31.12K	719.09K	22.57K	+263.97%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	0.06%	31.22K	721.59K	9.63K	+44.59%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.11%	55.08K	1.27M	0	0
Mar 31, 2024	MARSHALL WACE, LLP	0.11%	58.17K	1.34M	-1.96K	-3.25%
Mar 31, 2024	WALLEYE CAPITAL LLC	0.19%	97.18K	2.25M	19.31K	+24.80%
Mar 31, 2024	TD ASSET MANAGEMENT INC	0.22%	112.62K	2.6M	112.62K	+100.00%
Mar 31, 2024	CITADEL ADVISORS LLC	0.46%	238.31K	5.51M	96.85K	+68.46%
Mar 31, 2024	ROCK SPRINGS CAPITAL MANAGEMENT LP	1.44%	752.92K	17.4M	752.92K	+100.00%
Mar 31, 2024	SPHERA FUNDS MANAGEMENT LTD.	0.75%	392.88K	9.08M	147.88K	+60.36%
Mar 31, 2024	SOLEUS CAPITAL MANAGEMENT, L.P.	0.77%	401.9K	9.29M	184.51K	+84.87%
Mar 31, 2024	SOFINNOVA INVESTMENTS, INC.	1.12%	584.67K	13.51M	74.23K	+14.54%
Mar 31, 2024	FMR LLC	9.93%	5.19M	120.01M	0	0
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	1.45%	757.92K	17.52M	-84.78K	-10.06%
Mar 31, 2024	5AM VENTURE MANAGEMENT, LLC	1.53%	797.6K	18.43M	0	0
Mar 31, 2024	ECOR1 CAPITAL, LLC	1.72%	900K	20.8M	0	0
Mar 31, 2024	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	2.03%	1.06M	24.53M	249.36K	+30.70%
Mar 31, 2024	NOVO HOLDINGS A/S	2.23%	1.17M	26.99M	-371.3K	-24.12%
Mar 31, 2024	CORMORANT ASSET MANAGEMENT, LP	3.27%	1.71M	39.55M	0	0
Mar 31, 2024	COMMODORE CAPITAL LP	3.3%	1.73M	39.86M	925K	+115.63%
Mar 31, 2024	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	6.32%	3.3M	76.34M	-600.94K	-15.39%
Mar 31, 2024	VR ADVISER, LLC	6.49%	3.4M	78.47M	0	0
Mar 31, 2024	VIKING GLOBAL INVESTORS LP	6.99%	3.65M	84.43M	-3.61K	-0.10%
Mar 31, 2024	FORESITE CAPITAL MANAGEMENT IV, LLC	7.72%	4.04M	93.34M	0	0
Mar 31, 2024	GENERAL ATLANTIC, L.P.	14.4%	7.53M	174.05M	1.38M	+22.34%
Dec 31, 2023	SPHERA FUNDS MANAGEMENT LTD.	0.6%	245K	6.87M	245K	+100.00%
Dec 31, 2023	FORESITE CAPITAL MANAGEMENT IV, LLC	9.87%	4.04M	113.29M	295.39K	+7.89%
Dec 31, 2023	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	9.54%	3.9M	109.52M	-880.36K	-18.40%
Dec 31, 2023	VIKING GLOBAL INVESTORS LP	8.94%	3.66M	102.58M	425K	+13.15%
Dec 31, 2023	VR ADVISER, LLC	8.3%	3.4M	95.25M	1.83M	+117.18%
Dec 31, 2023	CORMORANT ASSET MANAGEMENT, LP	4.18%	1.71M	48.01M	350K	+25.71%
Dec 31, 2023	NOVO HOLDINGS A/S	3.76%	1.54M	43.18M	210K	+15.80%
Dec 31, 2023	ECOR1 CAPITAL, LLC	2.2%	900K	25.25M	900K	+100.00%
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	2.06%	842.7K	23.64M	842.7K	+100.00%
Dec 31, 2023	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	1.99%	812.24K	22.78M	812.24K	+100.00%
Dec 31, 2023	COMMODORE CAPITAL LP	1.96%	800K	22.44M	800K	+100.00%
Dec 31, 2023	5AM VENTURE MANAGEMENT, LLC	1.95%	797.6K	22.37M	210K	+35.74%
Dec 31, 2023	SOFINNOVA INVESTMENTS, INC.	1.25%	510.44K	14.32M	510.44K	+100.00%
Dec 31, 2023	VIVO CAPITAL, LLC	0.7%	285K	7.99M	285K	+100.00%
Dec 31, 2023	VENBIO PARTNERS LLC	12.03%	4.92M	137.99M	654.83K	+15.35%
Dec 31, 2023	SOLEUS CAPITAL MANAGEMENT, L.P.	0.53%	217.4K	6.1M	-126.58K	-36.80%
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	0.46%	188.52K	5.29M	188.52K	+100.00%
Dec 31, 2023	CITADEL ADVISORS LLC	0.35%	141.46K	3.97M	141.46K	+100.00%
Dec 31, 2023	BLACKSTONE INC.	0.24%	100K	2.81M	100K	+100.00%
Dec 31, 2023	WALLEYE CAPITAL LLC	0.19%	77.87K	2.18M	-3.15K	-3.88%
Dec 31, 2023	HUDSON BAY CAPITAL MANAGEMENT LP	0.17%	70.13K	1.97M	31.24K	+80.33%
Dec 31, 2023	MARSHALL WACE, LLP	0.15%	60.12K	1.69M	60.12K	+100.00%
Dec 31, 2023	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.13%	55.08K	1.54M	55.08K	+100.00%
Dec 31, 2023	QUBE RESEARCH & TECHNOLOGIES LTD	0.08%	32.32K	906.52K	29.74K	+1,153.12%
Dec 31, 2023	MORGAN STANLEY	0.06%	22.49K	630.79K	-11.21K	-33.26%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	0.05%	21.6K	605.74K	0	0
Dec 31, 2023	UBS OCONNOR LLC	0.04%	18K	504.9K	18K	+100.00%
Dec 31, 2023	SCHONFELD STRATEGIC ADVISORS LLC	0.03%	12.4K	347.82K	500	+4.20%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.02%	8.55K	239.8K	8.55K	+100.00%
Dec 31, 2023	TWO SIGMA INVESTMENTS, LP	0.02%	8.2K	229.95K	8.2K	+100.00%
Dec 31, 2023	BLACKROCK INC.	0.01%	2.27K	63.62K	0	0
Dec 31, 2023	QUARRY LP	0%	750	21.04K	750	+100.00%
Dec 31, 2023	JPMORGAN CHASE & CO	0%	190	5.33K	190	+100.00%
Dec 31, 2023	PIPER SANDLER & CO.	0%	181	5.08K	181	+100.00%
Dec 31, 2023	UBS GROUP AG	0%	0	-	-50	-100.00%
Dec 31, 2023	FORESITE CAPITAL MANAGEMENT V, LLC	0%	0	-	-33.14K	-100.00%
Dec 31, 2023	Y-INTERCEPT (HONG KONG) LTD	0%	0	-	-17.55K	-100.00%
Dec 31, 2023	GENERAL ATLANTIC, L.P.	15.05%	6.16M	172.68M	1.75M	+39.72%
Dec 31, 2023	FMR LLC	12.69%	5.19M	145.66M	1.99M	+61.90%
Sep 30, 2023	LYNX1 CAPITAL MANAGEMENT LP	0%	0	-	-21.23K	-100.00%
Sep 30, 2023	SILVERARC CAPITAL MANAGEMENT, LLC	0%	0	-	-200K	-100.00%
Sep 30, 2023	JPMORGAN CHASE & CO	0%	0	-	-151	-100.00%
Sep 30, 2023	UBS GROUP AG	0%	50	1.04K	-1.25K	-96.15%
Sep 30, 2023	BLACKROCK INC.	0.01%	2.27K	47.33K	2.11K	+1,353.85%
Sep 30, 2023	QUBE RESEARCH & TECHNOLOGIES LTD	0.01%	2.58K	53.82K	2.58K	+100.00%
Sep 30, 2023	SCHONFELD STRATEGIC ADVISORS LLC	0.03%	11.9K	248.35K	300	+2.59%
Sep 30, 2023	Y-INTERCEPT (HONG KONG) LTD	0.04%	17.55K	366.33K	17.55K	+100.00%
Sep 30, 2023	GEODE CAPITAL MANAGEMENT, LLC	0.05%	21.6K	450.69K	2.95K	+15.83%
Sep 30, 2023	FORESITE CAPITAL MANAGEMENT V, LLC	0.08%	33.14K	691.67K	-1K	-2.93%
Sep 30, 2023	MORGAN STANLEY	0.08%	33.7K	703.26K	-11.64K	-25.67%
Sep 30, 2023	HUDSON BAY CAPITAL MANAGEMENT LP	0.1%	38.89K	811.7K	38.89K	+100.00%
Sep 30, 2023	WALLEYE CAPITAL LLC	0.2%	81.02K	1.69M	10.69K	+15.20%
Sep 30, 2023	SOLEUS CAPITAL MANAGEMENT, L.P.	0.84%	343.98K	7.18M	-47.93K	-12.23%
Sep 30, 2023	5AM VENTURE MANAGEMENT, LLC	1.44%	587.6K	12.26M	0	0
Sep 30, 2023	NOVO HOLDINGS A/S	3.26%	1.33M	27.74M	0	0
Sep 30, 2023	CORMORANT ASSET MANAGEMENT, LP	3.34%	1.36M	28.41M	387.85K	+39.84%
Sep 30, 2023	VR ADVISER, LLC	3.83%	1.56M	32.63M	237.31K	+17.89%
Sep 30, 2023	FMR LLC	7.86%	3.21M	66.94M	-179.59K	-5.30%
Sep 30, 2023	GENERAL ATLANTIC, L.P.	10.79%	4.41M	91.96M	0	0
Sep 30, 2023	VIKING GLOBAL INVESTORS LP	7.92%	3.23M	67.45M	0	0
Sep 30, 2023	FORESITE CAPITAL MANAGEMENT IV, LLC	9.17%	3.74M	78.13M	0	0
Sep 30, 2023	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	11.72%	4.78M	99.86M	-84.11K	-1.73%
Sep 30, 2023	VENBIO PARTNERS LLC	10.45%	4.26M	89M	0	0

Insiders

Insiders	Designation	Shares Held
SCHIKAN JOHANNES GERARDUS CHRISTIAAN PETRUS	director	355.17K
MODIG BERNDT	Chief Executive Officer	135.21K
NASSIF DAVID W.	CFO / CLO	120.3K
LU PENG	Chief Medical Officer	66.08K
LESAGE ANNE	Chief Early Development	56.45K
NIJDAM ANNA	Principal Accounting Officer	46.28K
SOUVERIJNS WIM	Chief Commercial Officer	45.11K
ABELE STEFAN ANDREAS	Chief Technical Ops Officer	35.19K
BJORK ELISABETH	director	15.17K
GLASSMAN ROBERT	director	10.5K
MONGES VIVIANE	director	5.5K

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Jun 15, 2026	MODIG BERNDT	SALE	31.46	100	3.15K	135.21K
Jun 04, 2026	NIJDAM ANNA	SALE	30.87	2.67K	82.43K	46.28K
May 22, 2026	NIJDAM ANNA	SALE	30.74	5.5K	169.08K	48.95K
May 21, 2026	MONGES VIVIANE	SALE	30.29	9.67K	292.85K	5.5K
May 21, 2026	NASSIF DAVID W.	SALE	30.31	10K	303.08K	120.3K
May 21, 2026	NIJDAM ANNA	SALE	30.60	1.83K	55.97K	48.95K
May 20, 2026	BJORK ELISABETH	SALE	29.32	10K	293.17K	15.17K
May 18, 2026	MODIG BERNDT	SALE	29.22	2.29K	66.98K	137.5K
May 15, 2026	GLASSMAN ROBERT	SALE	29.82	4.67K	139.15K	10.5K
May 15, 2026	ABELE STEFAN ANDREAS	SALE	29.82	8.75K	260.86K	35.19K
May 15, 2026	SOUVERIJNS WIM	SALE	29.92	10K	299.16K	45.11K
May 01, 2026	LU PENG	SALE	31.00	143	4.43K	66.08K
Apr 30, 2026	LU PENG	SALE	30.24	15K	453.63K	66.08K
Apr 30, 2026	LESAGE ANNE	SALE	30.26	18K	544.6K	56.45K
Apr 30, 2026	SCHIKAN JOHANNES GERARDUS CHRISTIAAN PETRUS	SALE	31.03	670	20.79K	355.17K
Apr 29, 2026	LU PENG	SALE	30.06	3.73K	112.23K	62.35K
Apr 29, 2026	SCHIKAN JOHANNES GERARDUS CHRISTIAAN PETRUS	SALE	30.07	3.83K	115.17K	384.24K
Apr 29, 2026	LESAGE ANNE	SALE	30.08	3.7K	111.28K	56.45K
Apr 23, 2026	LU PENG	SALE	30.03	100	3K	66.08K
Apr 23, 2026	LESAGE ANNE	SALE	30.03	100	3K	56.45K
Apr 23, 2026	SCHIKAN JOHANNES GERARDUS CHRISTIAAN PETRUS	SALE	30.03	100	3K	388.07K
Apr 22, 2026	SCHIKAN JOHANNES GERARDUS CHRISTIAAN PETRUS	SALE	30.05	7K	210.38K	388.17K
Apr 22, 2026	LU PENG	SALE	30.05	7K	210.4K	66.08K
Apr 22, 2026	LESAGE ANNE	SALE	30.00	500	15K	56.45K
Apr 16, 2026	MODIG BERNDT	SALE	28.60	2.29K	65.56K	139.79K
Apr 09, 2026	MODIG BERNDT	SALE	28.41	200	5.68K	142.08K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES127.84K26

NET SHARES-127.84K26

SHARES HELD3M26

% NET SHARES-104.26%0%

PHVS Stock Ownership Breakdown

Pharvaris NV

Stock Outstanding Shares

Market Insider

Institutional Ownership

Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions

Stock Outstanding Shares

Market Insider

Institutional Ownership

Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions