How many institutions own PEPG stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own PEPG shares is 74, representing 89.5% of the company's common stock.

Who are the major shareholders selling PepGen Inc. stock?

CITIGROUP INC, in the last quarter, reduced its stake in PEPG by -77.37% restricting it's holding to 1.49 thousand shares of worth nearly $6.90K. JPMORGAN CHASE & CO also lessened -79.93% of the PEPG shares from its portfolio, reducing its holding to 2.18 thousand shares of worth $10.05K. FMR LLC also shunned PEPG shares holding by -56.63% last quarter which brought its holding to 2.43 thousand shares worth $11.23K.

Investors who are buying PEPG stock?

As per its latest 13F filing, NORTHERN TRUST CORP increased its stake in PEPG by 24.05% in the last quarter. The institutional holder raised its holding to 59.53 thousand shares having worth more than $275.01K. CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD. also added 100% more shares of PEPG to its portfolio, raising its holding to 38.08 thousand shares of worth $175.93K. ADAR1 CAPITAL MANAGEMENT, LLC also increased its PEPG shares holding by 81.02% which brought its holding to 36.84 thousand shares worth $170.21K.

PEPG's major insiders: who are they?

The insider with the most stakes in PEPG is RA CAPITAL MANAGEMENT, L.P. , at the company. Additionally, PEPG stock is highly held by Former 10% Owner Oxford Science Enterprises plc and Shah Rajeev M. among others.

Did an insider recently sell PEPG stock?

Company executives, directors, and other insiders own 0.27% percent of PepGen Inc.'s stock. Within the last six months, there have been 0 transaction(s) in which PEPG insiders have sold stock, totaling 0 shares. Insiders that have sold shares include DELENA MARY BETH, DONNELLY NOEL, and MELLION MICHELLE L.

Which insider recently purchased PEPG stock?

There have been 2 transaction(s) during the past 6-months in which PepGen Inc. insiders have bought stock, totalling 9575000 shares

How much of PEPG does insiders own?

Around 23.51M PepGen Inc. shares are held by insiders, which represents about 0.27% of PEPG stock.

Who is the insider with the largest stake?

PEPG , RA CAPITAL MANAGEMENT, L.P. holds the largest portfolio of the company's shares. PEPG shares owned by RA total nearly 18.55 million.

Which institution holds the most shares in PEPG?

CITIGROUP INC is the largest institutional owner in PEPG which holds 1.49 thousand shares worth $6.90K or 0% of the total PEPG shares outstanding followed by JPMORGAN CHASE & CO with ownership of 2.18 thousand shares representing 0.01% of the PEPG ownership. FMR LLC is the third largest stakeholder with 2.43 thousand shares or 0.01% of the ownership worth more than $11.23K.

Is PepGen Inc. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the PEPG is concerned, it is a stock which is optionable.

Is there a short position on PEPG's shares?

Number of PEPG shares short is 1.13M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding PEPG shares are there?

As of today, 32.80M shares of PEPG are outstanding.

Is there many float in PEPG stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, PEPG has 14.53M shares in float.

PEPG short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for PEPG is 3.54.

PepGen (PEPG) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares3.46

Short Percent Of Float6.54

Shares Outstanding32.80M

Shares Float14.53M

Shares Short1.13M

Short Ratio3.54

6.54%

Short % of Float

3.46%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

0.27% Percentage of Shares held by All Insiders

89.5% Percentage of Shares held by All Institutions

89.74% Percentage of Float held by Institutions

Number of Institutions Holding Shares

Institutional Ownership

About 89.5% of PEPG shares are held by financial institutions. CITIGROUP INC is the top corporate investor, holding 1.49K shares valued at $6.90K. A 0% stake in PepGen Inc. is owned by the company. JPMORGAN CHASE & CO owns 2.18K shares valued at $10.05K, which translates its holding of 0.01% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Sep 30, 2025	CITIGROUP INC	0%	1.49K	6.9K	-5.11K	-77.37%
Sep 30, 2025	JPMORGAN CHASE & CO	0.01%	2.18K	10.05K	-8.66K	-79.93%
Sep 30, 2025	FMR LLC	0.01%	2.43K	11.23K	-3.17K	-56.63%
Sep 30, 2025	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.02%	5.75K	26.56K	-823	-12.52%
Sep 30, 2025	NORTHERN TRUST CORP	0.18%	59.53K	275.01K	11.54K	+24.05%
Sep 30, 2025	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.12%	38.08K	175.93K	38.08K	+100.00%
Sep 30, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	0.11%	36.84K	170.21K	16.49K	+81.02%
Sep 30, 2025	DIMENSIONAL FUND ADVISORS LP	0.1%	33.01K	152.52K	-6.69K	-16.86%
Sep 30, 2025	RATHBONES GROUP PLC	0.1%	32K	147.85K	0	0
Sep 30, 2025	CUBIST SYSTEMATIC STRATEGIES, LLC	0.09%	30.67K	141.7K	30.67K	+100.00%
Sep 30, 2025	FIFTH LANE CAPITAL, LP	0.21%	70K	323.4K	70K	+100.00%
Sep 30, 2025	BANK OF MONTREAL /CAN/	0.06%	20K	92.41K	20K	+100.00%
Sep 30, 2025	MILITIA CAPITAL PARTNERS, LP	0.05%	15.5K	71.61K	15.5K	+100.00%
Sep 30, 2025	HEIGHTS CAPITAL MANAGEMENT, INC	0.03%	10K	46.2K	10K	+100.00%
Sep 30, 2025	LOGOS GLOBAL MANAGEMENT LP	2.29%	750K	3.47M	750K	+100.00%
Sep 30, 2025	BALYASNY ASSET MANAGEMENT L.P.	4.07%	1.33M	6.16M	1.33M	+100.00%
Sep 30, 2025	RANGELEY CAPITAL, LLC	0.13%	44K	203.28K	9K	+25.71%
Sep 30, 2025	JANUS HENDERSON GROUP PLC	4.58%	1.5M	6.92M	1.5M	+100.00%
Sep 30, 2025	LAURION CAPITAL MANAGEMENT LP	5.78%	1.89M	8.74M	1.08M	+133.38%
Sep 30, 2025	BVF INC/IL	5.85%	1.92M	8.85M	1.92M	+100.00%
Sep 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	6.2%	2.03M	9.38M	-729.17K	-26.43%
Sep 30, 2025	VIVO CAPITAL, LLC	7.1%	2.33M	10.74M	2.33M	+100.00%
Sep 30, 2025	COMMODORE CAPITAL LP	7.2%	2.36M	10.89M	2.36M	+100.00%
Sep 30, 2025	VANGUARD PERSONALIZED INDEXING MANAGEMENT, LLC	0%	0	-	-15.94K	-100.00%
Sep 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0%	0	-	-137	-100.00%
Sep 30, 2025	MARSHALL WACE, LLP	0%	0	-	-39.21K	-100.00%
Sep 30, 2025	GROUP ONE TRADING, L.P.	0%	0	-	-4.04K	-100.00%
Sep 30, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.19%	63K	291.06K	-28.92K	-31.46%
Sep 30, 2025	UBS GROUP AG	0.74%	242.45K	1.12M	229.09K	+1,714.48%
Sep 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	1.47%	481.37K	2.22M	481.37K	+100.00%
Sep 30, 2025	AWM INVESTMENT COMPANY, INC.	3.13%	1.03M	4.74M	1.03M	+100.00%
Sep 30, 2025	RA CAPITAL MANAGEMENT, L.P.	61.27%	20.06M	92.7M	9.38M	+87.70%
Sep 30, 2025	GSA CAPITAL PARTNERS LLP	0.14%	46.16K	213K	46.16K	+100.00%
Sep 30, 2025	RTW INVESTMENTS, LP	4.58%	1.5M	6.93M	1.5M	+100.00%
Sep 30, 2025	BOXER CAPITAL MANAGEMENT, LLC	0.76%	250K	1.16M	250K	+100.00%
Sep 30, 2025	JANE STREET GROUP, LLC	3.34%	1.09M	5.05M	1.09M	+100.00%
Sep 30, 2025	DEEP TRACK CAPITAL, LP	3.66%	1.2M	5.54M	1.2M	+100.00%
Sep 30, 2025	PNC FINANCIAL SERVICES GROUP, INC.	0%	0	-	-35	-100.00%
Sep 30, 2025	STATE STREET CORP	0.2%	65.79K	303.95K	-3.35K	-4.85%
Sep 30, 2025	IKARIAN CAPITAL, LLC	1.64%	535.97K	2.48M	385.97K	+257.31%
Sep 30, 2025	MORGAN STANLEY	1.76%	575.16K	2.66M	510.32K	+787.07%
Sep 30, 2025	SIREN, L.L.C.	2.14%	700K	3.23M	700K	+100.00%
Sep 30, 2025	OCTAGON CAPITAL ADVISORS LP	2.14%	700K	3.23M	700K	+100.00%
Sep 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	4.43%	1.45M	6.7M	100K	+7.41%
Sep 30, 2025	OPALEYE MANAGEMENT INC.	0.23%	75K	346.5K	-165K	-68.75%
Sep 30, 2025	RBF CAPITAL, LLC	0.31%	100K	462K	0	0
Sep 30, 2025	MONIMUS CAPITAL MANAGEMENT, LP	0.32%	104.8K	484.18K	104.8K	+100.00%
Sep 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.4%	131.63K	608.14K	89.33K	+211.15%
Sep 30, 2025	ACADIAN ASSET MANAGEMENT LLC	0.46%	150.19K	693K	150.19K	+100.00%
Sep 30, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.52%	171.47K	792.18K	15K	+9.59%
Sep 30, 2025	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.58%	190.26K	878.98K	190.26K	+100.00%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.61%	200.73K	927.77K	-365	-0.18%
Sep 30, 2025	MONASHEE INVESTMENT MANAGEMENT LLC	0.92%	300K	1.39M	300K	+100.00%
Sep 30, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	0.96%	315K	1.46M	315K	+100.00%
Sep 30, 2025	BOOTHBAY FUND MANAGEMENT, LLC	1.07%	350.39K	1.62M	304.82K	+668.89%
Sep 30, 2025	STEMPOINT CAPITAL LP	1.19%	389.19K	1.8M	389.19K	+100.00%
Sep 30, 2025	BLACKROCK, INC.	1.37%	450.13K	2.08M	-197.9K	-30.54%
Sep 30, 2025	MILLENNIUM MANAGEMENT LLC	1.53%	500.27K	2.31M	-1.01M	-66.85%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0%	0	-	-327	-100.00%
Sep 30, 2025	NISA INVESTMENT ADVISORS, LLC	0%	195	901	-310	-61.39%
Sep 30, 2025	GF FUND MANAGEMENT CO. LTD.	0%	679	3.14K	-129	-15.97%
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.23%	75.7K	349.73K	24.4K	+47.56%
Sep 30, 2025	TCG CROSSOVER MANAGEMENT, LLC	3.66%	1.2M	5.54M	1.2M	+100.00%
Sep 30, 2025	CWM, LLC	0%	767	4K	-2.81K	-78.55%
Sep 30, 2025	BARCLAYS PLC	0%	1.16K	5.34K	-2.55K	-68.79%
Sep 30, 2025	MIRAE ASSET GLOBAL INVESTMENTS CO., LTD.	0%	1.27K	5.86K	4	+0.32%
Sep 30, 2025	VIKING GLOBAL INVESTORS LP	10.63%	3.48M	16.09M	2M	+134.91%
Sep 30, 2025	WOODLINE PARTNERS LP	4%	1.31M	6.06M	619.49K	+89.58%
Sep 30, 2025	VANGUARD GROUP INC	5.4%	1.77M	8.17M	831.33K	+88.72%
Sep 30, 2025	PERCEPTIVE ADVISORS LLC	2.53%	829.87K	3.83M	829.87K	+100.00%
Sep 30, 2025	ECOR1 CAPITAL, LLC	2.44%	800K	3.7M	800K	+100.00%
Sep 30, 2025	TWO SIGMA INVESTMENTS, LP	0.28%	92.49K	427.32K	28.75K	+45.11%
Sep 30, 2025	CITADEL ADVISORS LLC	0.26%	84.4K	389.93K	84.4K	+100.00%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0%	1.4K	6.45K	-7.13K	-83.62%
Jun 30, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	0.06%	20.35K	22.59K	0	0
Jun 30, 2025	SUVRETTA CAPITAL MANAGEMENT, LLC	0.92%	300K	333K	-1.36M	-81.94%
Jun 30, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.48%	156.47K	173.68K	156.47K	+100.00%
Jun 30, 2025	XTX TOPCO LTD	0%	0	-	-18.14K	-100.00%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.61%	201.1K	223.3K	-182.8K	-47.62%
Jun 30, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.28%	91.92K	102.04K	35K	+61.49%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.22%	70.6K	78.37K	30.36K	+75.45%
Jun 30, 2025	STATE STREET CORP	0.21%	69.14K	76.75K	-250.96K	-78.40%
Jun 30, 2025	TWO SIGMA INVESTMENTS, LP	0.19%	63.74K	70.75K	17.55K	+37.98%
Jun 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.16%	51.3K	56.94K	6K	+13.24%
Jun 30, 2025	NORTHERN TRUST CORP	0.15%	47.99K	53.26K	-93.05K	-65.98%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0.03%	10.34K	11.47K	-8.39K	-44.79%
Jun 30, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0.03%	9.57K	10.62K	3.41K	+55.38%
Jun 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.03%	8.52K	9.46K	6.62K	+346.93%
Jun 30, 2025	GF FUND MANAGEMENT CO. LTD.	0%	808	897	0	0
Jun 30, 2025	RANGELEY CAPITAL, LLC	0.11%	35K	38.85K	20K	+133.33%
Jun 30, 2025	VANGUARD GROUP INC	2.86%	937.02K	1.04M	37.29K	+4.14%
Jun 30, 2025	MILLENNIUM MANAGEMENT LLC	4.61%	1.51M	1.68M	476.18K	+46.10%
Jun 30, 2025	MIRAE ASSET GLOBAL INVESTMENTS CO., LTD.	0%	1.26K	1.4K	243	+23.80%
Jun 30, 2025	ROYAL BANK OF CANADA	0%	1.53K	1K	1.53K	+100.00%
Jun 30, 2025	CWM, LLC	0.01%	3.58K	4K	-2.46K	-40.79%
Jun 30, 2025	BARCLAYS PLC	0.01%	3.7K	4K	-18.34K	-83.20%
Jun 30, 2025	JPMORGAN CHASE & CO	0.03%	10.84K	12.03K	780	+7.76%
Jun 30, 2025	UBS GROUP AG	0.04%	13.36K	14.83K	-20.91K	-61.01%
Jun 30, 2025	DIMENSIONAL FUND ADVISORS LP	0.12%	39.7K	44.12K	-14.93K	-27.33%
Jun 30, 2025	RATHBONES GROUP PLC	0.1%	32K	35.52K	0	0
Jun 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0%	0	-	-6.49K	-100.00%
Jun 30, 2025	STRS OHIO	0%	0	-	-10.2K	-100.00%
Jun 30, 2025	DEUTSCHE BANK AG\	0%	0	-	-48.52K	-100.00%
Jun 30, 2025	AMERITAS INVESTMENT PARTNERS, INC.	0%	0	-	-1.18K	-100.00%
Jun 30, 2025	MIRAE ASSET GLOBAL ETFS HOLDINGS LTD.	0%	0	-	-9.29K	-100.00%
Jun 30, 2025	COREBRIDGE FINANCIAL, INC.	0%	0	-	-7.61K	-100.00%
Jun 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0%	137	152	-2.6K	-95.00%
Jun 30, 2025	WELLS FARGO & COMPANY/MN	0%	327	363	-7.31K	-95.72%
Jun 30, 2025	NISA INVESTMENT ADVISORS, LLC	0%	505	561	210	+71.19%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.13%	42.31K	46.96K	-33.3K	-44.05%
Jun 30, 2025	GROUP ONE TRADING, L.P.	0.01%	4.04K	4.48K	-5.86K	-59.20%
Jun 30, 2025	FMR LLC	0.02%	5.6K	6.22K	-14.39K	-71.97%
Jun 30, 2025	CITIGROUP INC	0.02%	6.6K	7.33K	-5.8K	-46.77%
Jun 30, 2025	AQR CAPITAL MANAGEMENT LLC	0.1%	32.71K	36.3K	-54.3K	-62.41%
Jun 30, 2025	ZACKS INVESTMENT MANAGEMENT	0.12%	38.05K	42.23K	0	0
Jun 30, 2025	MARSHALL WACE, LLP	0.12%	39.21K	43.52K	39.21K	+100.00%
Jun 30, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.14%	45.57K	50.58K	0	0
Jun 30, 2025	MORGAN STANLEY	0.2%	64.84K	71.97K	32	+0.05%
Jun 30, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.22%	73K	81.03K	73K	+100.00%
Jun 30, 2025	IKARIAN CAPITAL, LLC	0.46%	150K	166.5K	0	0
Jun 30, 2025	OPALEYE MANAGEMENT INC.	0.73%	240K	266.4K	-180K	-42.86%
Jun 30, 2025	LAURION CAPITAL MANAGEMENT LP	2.48%	810.76K	899.95K	0	0
Jun 30, 2025	VIKING GLOBAL INVESTORS LP	4.53%	1.48M	1.65M	0	0
Jun 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	8.43%	2.76M	3.06M	83.23K	+3.11%
Jun 30, 2025	TRUE WEALTH DESIGN, LLC	0%	0	-	-145	-100.00%
Jun 30, 2025	CORECAP ADVISORS, LLC	0%	0	-	-546	-100.00%
Jun 30, 2025	EVERSOURCE WEALTH ADVISORS, LLC	0%	0	-	-1	-100.00%
Jun 30, 2025	BANK OF NEW YORK MELLON CORP	0%	0	-	-33.47K	-100.00%
Jun 30, 2025	STERLING CAPITAL MANAGEMENT LLC	0%	0	-	-20	-100.00%
Jun 30, 2025	UBS OCONNOR LLC	0%	0	-	-26.56K	-100.00%
Jun 30, 2025	RHUMBLINE ADVISERS	0%	0	-	-19.07K	-100.00%
Jun 30, 2025	ALLIANCEBERNSTEIN L.P.	0%	0	-	-17.65K	-100.00%
Jun 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0%	0	-	-17.63K	-100.00%
Jun 30, 2025	COLDSTREAM CAPITAL MANAGEMENT INC	0%	0	-	-67	-100.00%
Jun 30, 2025	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0%	0	-	-1.13K	-100.00%
Jun 30, 2025	SEI INVESTMENTS CO	0%	0	-	-70.14K	-100.00%
Jun 30, 2025	RBF CAPITAL, LLC	0.31%	100K	111K	100K	+100.00%
Jun 30, 2025		0%	808	897	0	0
Jun 30, 2025	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.02%	6.57K	7.3K	14	+0.21%
Jun 30, 2025	RA CAPITAL MANAGEMENT, L.P.	32.64%	10.69M	11.87M	0	0
Jun 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	4.12%	1.35M	1.5M	0	0
Jun 30, 2025	WOODLINE PARTNERS LP	2.11%	691.53K	767.6K	-89.37K	-11.44%
Jun 30, 2025	BLACKROCK, INC.	1.98%	648.02K	719.3K	-646.23K	-49.93%
Jun 30, 2025	PROSIGHT MANAGEMENT, LP	0.75%	243.98K	270.82K	243.98K	+100.00%
Jun 30, 2025	VANGUARD PERSONALIZED INDEXING MANAGEMENT, LLC	0.05%	15.94K	17.69K	5.34K	+50.37%
Jun 30, 2025	LEGAL & GENERAL GROUP PLC	0%	0	-	-1.68K	-100.00%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0%	0	-	-40.07K	-100.00%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.17%	383.89K	539.5K	11.04K	+2.96%
Mar 31, 2025	STATE STREET CORP	0.98%	320.1K	449.75K	-2.79K	-0.86%
Mar 31, 2025	IKARIAN CAPITAL, LLC	0.46%	150K	210.75K	150K	+100.00%
Mar 31, 2025	MORGAN STANLEY	0.2%	64.81K	91.05K	-488.67K	-88.29%
Mar 31, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.14%	45.57K	64.03K	45.57K	+100.00%
Mar 31, 2025	RA CAPITAL MANAGEMENT, L.P.	32.72%	10.69M	15.02M	0	0
Mar 31, 2025	VANGUARD PERSONALIZED INDEXING MANAGEMENT, LLC	0.03%	10.6K	14.89K	10.6K	+100.00%
Mar 31, 2025	ZACKS INVESTMENT MANAGEMENT	0.12%	38.05K	53.46K	0	0
Mar 31, 2025	RHUMBLINE ADVISERS	0.06%	19.07K	26.79K	117	+0.62%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0.06%	18.72K	26.3K	-35.15K	-65.24%
Mar 31, 2025	CITIGROUP INC	0.04%	12.4K	17.43K	17	+0.14%
Mar 31, 2025	STRS OHIO	0.03%	10.2K	14.33K	0	0
Mar 31, 2025	UBS OCONNOR LLC	0.08%	26.56K	37.32K	26.56K	+100.00%
Mar 31, 2025	BARCLAYS PLC	0.07%	22.04K	31K	-4.37K	-16.54%
Mar 31, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	0.06%	20.35K	28.6K	20.35K	+100.00%
Mar 31, 2025	FMR LLC	0.06%	19.99K	28.09K	19.41K	+3,334.54%
Mar 31, 2025	RATHBONES GROUP PLC	0.1%	32K	44.96K	0	0
Mar 31, 2025	CITADEL ADVISORS LLC	0.06%	19.6K	27.54K	19.6K	+100.00%
Mar 31, 2025	XTX TOPCO LTD	0.06%	18.14K	25.49K	18.14K	+100.00%
Mar 31, 2025	ALLIANCEBERNSTEIN L.P.	0.05%	17.65K	24.8K	0	0
Mar 31, 2025	VIKING GLOBAL INVESTORS LP	4.54%	1.48M	2.08M	0	0
Mar 31, 2025	BANK OF NEW YORK MELLON CORP	0.1%	33.47K	47.02K	-20	-0.06%
Mar 31, 2025	NORTHERN TRUST CORP	0.43%	141.04K	198.16K	-16K	-10.19%
Mar 31, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.05%	17.63K	24.77K	17.63K	+100.00%
Mar 31, 2025		0.05%	15K	21.08K	15K	+100.00%
Mar 31, 2025	VANGUARD GROUP INC	2.75%	899.73K	1.26M	-12.94K	-1.42%
Mar 31, 2025	LAURION CAPITAL MANAGEMENT LP	2.48%	810.76K	1.14M	0	0
Mar 31, 2025	WOODLINE PARTNERS LP	2.39%	780.9K	1.1M	780.9K	+100.00%
Mar 31, 2025	OPALEYE MANAGEMENT INC.	1.29%	420K	590.1K	310K	+281.82%
Mar 31, 2025	JPMORGAN CHASE & CO	0.03%	10.06K	14.13K	-21.23K	-67.86%
Mar 31, 2025	GROUP ONE TRADING, L.P.	0.03%	9.9K	13.91K	9.9K	+100.00%
Mar 31, 2025	MIRAE ASSET GLOBAL ETFS HOLDINGS LTD.	0.03%	9.29K	13.05K	390	+4.38%
Mar 31, 2025	POINT72 ASSET MANAGEMENT, L.P.	8.19%	2.68M	3.76M	2.68M	+100.00%
Mar 31, 2025	SUVRETTA CAPITAL MANAGEMENT, LLC	5.08%	1.66M	2.33M	486.61K	+41.44%
Mar 31, 2025	BLACKROCK, INC.	3.96%	1.29M	1.82M	8.13K	+0.63%
Mar 31, 2025	AQR CAPITAL MANAGEMENT LLC	0.27%	87K	122.24K	87K	+100.00%
Mar 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.23%	75.61K	106.23K	75.61K	+100.00%
Mar 31, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	4.13%	1.35M	1.9M	550K	+68.75%
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	3.16%	1.03M	1.45M	876.38K	+559.50%
Mar 31, 2025	SEI INVESTMENTS CO	0.21%	70.14K	98.55K	70.14K	+100.00%
Mar 31, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.17%	56.92K	79.98K	-41.98K	-42.44%
Mar 31, 2025	DIMENSIONAL FUND ADVISORS LP	0.17%	54.63K	76.86K	-2.47K	-4.33%
Mar 31, 2025	DEUTSCHE BANK AG\	0.15%	48.52K	68.41K	3.78K	+8.46%
Mar 31, 2025	TWO SIGMA INVESTMENTS, LP	0.14%	46.19K	64.9K	46.19K	+100.00%
Mar 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0.14%	45.3K	63.65K	45.3K	+100.00%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.12%	40.24K	56.54K	-58.1K	-59.08%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.12%	40.07K	56.3K	-8.28K	-17.13%
Mar 31, 2025	UBS GROUP AG	0.1%	34.27K	48.15K	22.25K	+185.19%
Mar 31, 2024	CRESTLINE MANAGEMENT, LP	0.15%	35K	514.5K	35K	+100.00%
Mar 31, 2024	AMALGAMATED BANK	0%	337	5K	-876	-72.22%
Mar 31, 2024	METROPOLITAN LIFE INSURANCE CO/NY	0%	596	8.76K	596	+100.00%
Mar 31, 2024	LEGAL & GENERAL GROUP PLC	0%	853	12.54K	0	0
Mar 31, 2024	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0%	1.01K	14.85K	-644	-38.94%
Mar 31, 2024	AMERITAS INVESTMENT PARTNERS, INC.	0%	1.18K	17.27K	0	0
Mar 31, 2024	ACADIAN ASSET MANAGEMENT LLC	0.01%	2.05K	30K	2.05K	+100.00%
Mar 31, 2024	WELLS FARGO & COMPANY/MN	0.01%	3.48K	51.1K	502	+16.88%
Mar 31, 2024	STRS OHIO	0.02%	3.6K	52K	1.7K	+89.47%
Mar 31, 2024	DEUTSCHE BANK AG\	0.02%	4.23K	62.17K	4.23K	+100.00%
Mar 31, 2024	AMERICAN INTERNATIONAL GROUP, INC.	0.02%	4.95K	72.81K	-43	-0.86%
Mar 31, 2024	METLIFE INVESTMENT MANAGEMENT, LLC	0.02%	5.79K	85.17K	5.79K	+100.00%
Mar 31, 2024	NEW YORK STATE COMMON RETIREMENT FUND	0.03%	6.48K	95K	-3	-0.05%
Mar 31, 2024	BARCLAYS PLC	0.03%	7K	103K	-6.72K	-48.97%
Mar 31, 2024	UBS GROUP AG	0.04%	10.06K	147.84K	-857	-7.85%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.06%	13.85K	203.57K	0	0
Mar 31, 2024	RHUMBLINE ADVISERS	0.06%	13.85K	203.6K	10	+0.07%
Mar 31, 2024	JPMORGAN CHASE & CO	0.07%	15.48K	227.59K	5.34K	+52.64%
Mar 31, 2024	AMERICAN CENTURY COMPANIES INC	0.07%	16.7K	245.52K	16.7K	+100.00%
Mar 31, 2024	QUBE RESEARCH & TECHNOLOGIES LTD	0.1%	24.79K	364.35K	24.66K	+20,051.22%
Mar 31, 2024	MORGAN STANLEY	0.12%	28.48K	418.69K	-7.44K	-20.70%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.13%	30.76K	452.17K	-658	-2.09%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.13%	31.29K	459.96K	3.5K	+12.59%
Mar 31, 2024	RATHBONES GROUP PLC	0.13%	32K	470.44K	-30K	-48.38%
Mar 31, 2024	CITIGROUP INC	0.17%	40.61K	596.97K	39.24K	+2,864.23%
Mar 31, 2024	LAURION CAPITAL MANAGEMENT LP	3.54%	841.43K	12.37M	176.92K	+26.62%
Mar 31, 2024	JANUS HENDERSON GROUP PLC	4.9%	1.17M	17.23M	178.44K	+18.06%
Mar 31, 2024	ADAGE CAPITAL PARTNERS GP, L.L.C.	5.6%	1.33M	19.6M	233.61K	+21.24%
Mar 31, 2024	PERCEPTIVE ADVISORS LLC	5.93%	1.41M	20.73M	1.41M	+100.00%
Mar 31, 2024	VIKING GLOBAL INVESTORS LP	6.23%	1.48M	21.79M	0	0
Mar 31, 2024	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	6.32%	1.5M	22.09M	1.5M	+100.00%
Mar 31, 2024	SUVRETTA CAPITAL MANAGEMENT, LLC	6.39%	1.52M	22.36M	1.03M	+212.56%
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	0.05%	12.06K	177.28K	0	0
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.06%	13.21K	194.23K	-943	-6.66%
Mar 31, 2024	WALLEYE CAPITAL LLC	0.27%	64.61K	949.83K	64.61K	+100.00%
Mar 31, 2024	MONASHEE INVESTMENT MANAGEMENT LLC	0.36%	85.89K	1.26M	85.89K	+100.00%
Mar 31, 2024	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.42%	99.2K	1.46M	0	0
Mar 31, 2024	SUPERSTRING CAPITAL MANAGEMENT LP	0.48%	114.39K	1.68M	114.39K	+100.00%
Mar 31, 2024	POINT72 ASSET MANAGEMENT, L.P.	0.81%	192.18K	2.83M	192.18K	+100.00%
Mar 31, 2024	ARTAL GROUP S.A.	0.84%	200K	2.94M	200K	+100.00%
Mar 31, 2024	STATE STREET CORP	1.01%	240.98K	3.54M	24.07K	+11.10%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	1.26%	299.49K	4.4M	89.43K	+42.58%
Mar 31, 2024	OCTAGON CAPITAL ADVISORS LP	1.58%	376.12K	5.53M	376.12K	+100.00%
Mar 31, 2024	SOFINNOVA INVESTMENTS, INC.	2.12%	503.62K	7.4M	480.59K	+2,086.06%
Mar 31, 2024	ZURCHER KANTONALBANK (ZURICH CANTONALBANK)	0%	1	15	0	0
Mar 31, 2024	NELSON, VAN DENBURG & CAMPBELL WEALTH MANAGEMENT GROUP, LLC	0%	2	29	2	+100.00%
Mar 31, 2024	NISA INVESTMENT ADVISORS, LLC	0%	9	132	9	+100.00%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.08%	19.06K	280.14K	3.27K	+20.69%
Mar 31, 2024	NORTHERN TRUST CORP	0.39%	92.2K	1.36M	17.37K	+23.21%
Mar 31, 2024	FMR LLC	1.93%	458.64K	6.74M	-279.38K	-37.86%
Mar 31, 2024	BLACKROCK INC.	3.28%	781.44K	11.49M	57.9K	+8.00%
Mar 31, 2024	VANGUARD GROUP INC	3.57%	850.45K	12.5M	344.27K	+68.01%
Mar 31, 2024	RA CAPITAL MANAGEMENT, L.P.	44.92%	10.69M	157.14M	2.56M	+31.45%
Dec 31, 2023	AMERICAN INTERNATIONAL GROUP, INC.	0.02%	5K	33.97K	-20	-0.40%
Dec 31, 2023	JPMORGAN CHASE & CO	0.04%	10.14K	68.97K	-818	-7.46%
Dec 31, 2023	UBS GROUP AG	0.05%	10.91K	74.22K	5.76K	+111.92%
Dec 31, 2023	JANE STREET GROUP, LLC	0.05%	11.23K	76.35K	11.23K	+100.00%
Dec 31, 2023	ALLIANCEBERNSTEIN L.P.	0.05%	12.06K	82.01K	0	0
Dec 31, 2023	BARCLAYS PLC	0.06%	13.72K	93K	12.1K	+743.00%
Dec 31, 2023	RHUMBLINE ADVISERS	0.06%	13.84K	94.11K	-808	-5.52%
Dec 31, 2023	NUVEEN ASSET MANAGEMENT, LLC	0.06%	13.85K	94.17K	0	0
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.06%	14.16K	96.26K	14.16K	+100.00%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.07%	15.79K	107.37K	-2.22K	-12.31%
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	0.08%	19.81K	134.69K	3.5K	+21.43%
Dec 31, 2023	SOFINNOVA INVESTMENTS, INC.	0.1%	23.04K	156.66K	23.04K	+100.00%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.12%	27.79K	188.97K	0	0
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.13%	31.42K	213.64K	20	+0.06%
Dec 31, 2023	MORGAN STANLEY	0.15%	35.92K	244.24K	25.99K	+261.63%
Dec 31, 2023	RATHBONES GROUP PLC	0.26%	62K	421.62K	0	0
Dec 31, 2023	NORTHERN TRUST CORP	0.31%	74.83K	508.81K	90	+0.12%
Dec 31, 2023	NEW YORK STATE COMMON RETIREMENT FUND	0.03%	6.48K	44K	-31	-0.48%
Dec 31, 2023	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.42%	99.2K	674.56K	42.9K	+76.20%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	0.88%	210.05K	1.43M	10.78K	+5.41%
Dec 31, 2023	STATE STREET CORP	0.91%	216.91K	1.48M	-2.21K	-1.01%
Dec 31, 2023	SAMSARA BIOCAPITAL, LLC	1.84%	436.81K	2.97M	-214.24K	-32.91%
Dec 31, 2023	SUVRETTA CAPITAL MANAGEMENT, LLC	2.05%	486.61K	3.31M	0	0
Dec 31, 2023	VANGUARD GROUP INC	2.13%	506.18K	3.44M	3.39K	+0.67%
Dec 31, 2023	LAURION CAPITAL MANAGEMENT LP	2.79%	664.52K	4.52M	0	0
Dec 31, 2023	BLACKROCK INC.	3.04%	723.54K	4.92M	-111.73K	-13.38%
Dec 31, 2023	FMR LLC	3.1%	738.02K	5.02M	-1.63M	-68.81%
Dec 31, 2023	JANUS HENDERSON GROUP PLC	4.15%	988.2K	6.74M	988.2K	+100.00%
Dec 31, 2023	ADAGE CAPITAL PARTNERS GP, L.L.C.	4.62%	1.1M	7.48M	420K	+61.76%
Dec 31, 2023	VIKING GLOBAL INVESTORS LP	6.23%	1.48M	10.08M	0	0
Dec 31, 2023	RA CAPITAL MANAGEMENT, L.P.	34.18%	8.13M	55.3M	0	0
Dec 31, 2023	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0%	0	-	-615	-100.00%
Dec 31, 2023	ALLSPRING GLOBAL INVESTMENTS HOLDINGS, LLC	0%	0	-	-6.56K	-100.00%
Dec 31, 2023	RENAISSANCE TECHNOLOGIES LLC	0%	0	-	-10K	-100.00%
Dec 31, 2023	NISA INVESTMENT ADVISORS, LLC	0%	0	-	-1.4K	-100.00%
Dec 31, 2023	ZURCHER KANTONALBANK (ZURICH CANTONALBANK)	0%	1	7	-1.31K	-99.92%
Dec 31, 2023	QUBE RESEARCH & TECHNOLOGIES LTD	0%	123	836	-1K	-89.06%
Dec 31, 2023	LEGAL & GENERAL GROUP PLC	0%	853	5.8K	-285	-25.04%
Dec 31, 2023	AMERITAS INVESTMENT PARTNERS, INC.	0%	1.18K	7.99K	0	0
Dec 31, 2023	AMALGAMATED BANK	0.01%	1.21K	8K	-162	-11.78%
Dec 31, 2023	CITIGROUP INC	0.01%	1.37K	9.32K	1.07K	+355.15%
Dec 31, 2023	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0.01%	1.65K	11.25K	-564	-25.43%
Dec 31, 2023	TOWER RESEARCH CAPITAL LLC (TRC)	0.01%	1.76K	11.97K	-2.23K	-55.88%
Dec 31, 2023	STRS OHIO	0.01%	1.9K	12K	0	0
Dec 31, 2023	WELLS FARGO & COMPANY/MN	0.01%	2.97K	20.22K	606	+25.59%
Dec 31, 2023	ROYAL BANK OF CANADA	0.01%	3.18K	22K	1.52K	+91.27%

Insiders

Among the PEPG insiders holding of 0.27% of the stake in company, RA CAPITAL MANAGEMENT, L.P., , holds the largest shares of 18.55M. OXFORD SCIENCE ENTERPRISES PLC, Former 10% Owner, is the second largest PEPG insider with ownership of 4.96M shares. SHAH RAJEEV M., , stands third with possession of 1.3M shares of that stake.

Insiders	Designation	Shares Held
RA CAPITAL MANAGEMENT, L.P.		18.55M
OXFORD SCIENCE ENTERPRISES PLC	Former 10% Owner	4.96M
SHAH RAJEEV M.		1.3M
FLYNN JAMES E	Possible Member of 10% Group	476.81K
DEERFIELD PRIVATE DESIGN FUND V, L.P.		476.81K
MCARTHUR JAMES G	President and CEO	113.91K
STRECK PAUL	EVP, Head of R&D	27.81K
KEATING LAURIE	director	4.17K
DONNELLY NOEL	Chief Financial Officer	1.67K
DELENA MARY BETH	General Counsel	1.57K
MELLION MICHELLE L	Chief Medical Officer	0
SVENSTRUP NIELS	SVP, Chem. Mfg & Controls	0
GOYAL JAYA	EVP, Res. & Preclin. Dev.	0

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Sep 30, 2025	OXFORD SCIENCE ENTERPRISES PLC	PURCHASE	3.20	200K	640K	4.96M
Sep 26, 2025	RA CAPITAL MANAGEMENT, L.P.	PURCHASE	3.20	9.38M	30M	18.55M
May 30, 2025	STRECK PAUL	PURCHASE	1.24	8.38K	10.39K	27.81K
Apr 17, 2025	MCARTHUR JAMES G	PURCHASE	1.35	10K	13.55K	113.91K
Apr 08, 2025	MCARTHUR JAMES G	PURCHASE	1.15	41.5K	47.73K	103.91K
Feb 26, 2025	DELENA MARY BETH	SALE	1.68	1.43K	2.41K	1.57K
Feb 26, 2025	DONNELLY NOEL	SALE	1.68	1.53K	2.57K	1.67K
Jul 25, 2024	MELLION MICHELLE L	SALE	18.06	7.57K	136.74K	0
Jul 24, 2024	MELLION MICHELLE L	SALE	18.01	201	3.62K	0
Jul 18, 2024	MELLION MICHELLE L	SALE	18.20	12.63K	229.8K	0
Jul 16, 2024	MELLION MICHELLE L	SALE	18.00	5.9K	106.25K	0
Jul 12, 2024	MELLION MICHELLE L	SALE	18.04	3.29K	59.33K	0
Jul 02, 2024	MELLION MICHELLE L	SALE	18.07	37	668.59	0
Jul 01, 2024	MELLION MICHELLE L	SALE	18.01	875	15.76K	0
Jun 24, 2024	MELLION MICHELLE L	SALE	18.19	9.26K	168.43K	0
Jun 12, 2024	MELLION MICHELLE L	SALE	18.06	1.09K	19.61K	0
Jun 11, 2024	MELLION MICHELLE L	SALE	18.04	500	9.02K	0
Jun 06, 2024	MELLION MICHELLE L	SALE	18.00	1.41K	25.4K	0
Jun 05, 2024	MELLION MICHELLE L	SALE	18.09	7.25K	131.06K	0
May 17, 2024	SVENSTRUP NIELS	SALE	13.41	10K	134.1K	0
Feb 09, 2024	RA CAPITAL MANAGEMENT, L.P.	PURCHASE	10.64	2.56M	27.21M	9.18M
Nov 30, 2023	MCARTHUR JAMES G	PURCHASE	4.17	1.69K	7.06K	1.69K
Jun 08, 2023	MCARTHUR JAMES G	SALE	16.04	2.38K	38.19K	0
Jun 07, 2023	MCARTHUR JAMES G	SALE	16.23	8.42K	136.62K	0
Jun 06, 2023	MCARTHUR JAMES G	SALE	16.18	18.15K	293.66K	0
Jun 05, 2023	MCARTHUR JAMES G	SALE	16.06	500	8.03K	0
Jun 02, 2023	MCARTHUR JAMES G	SALE	16.04	1.8K	28.86K	0
Mar 24, 2023	GOYAL JAYA	SALE	20.00	392	7.84K	0
Feb 08, 2023	GOYAL JAYA	SALE	17.00	644	10.95K	0
Feb 07, 2023	GOYAL JAYA	SALE	17.18	3.68K	63.21K	0
Feb 06, 2023	GOYAL JAYA	SALE	17.04	1.68K	28.57K	0
May 10, 2022	OXFORD SCIENCE ENTERPRISES PLC	PURCHASE	12.00	879.97K	10.56M	4.76M
May 10, 2022	RA CAPITAL MANAGEMENT, L.P.	PURCHASE	12.00	249.75K	3M	1.3M
May 10, 2022	SHAH RAJEEV M.	PURCHASE	12.00	249.75K	3M	1.3M
May 10, 2022	FLYNN JAMES E	PURCHASE	12.00	208.33K	2.5M	476.81K
May 10, 2022	DEERFIELD PRIVATE DESIGN FUND V, L.P.	PURCHASE	12.00	208.33K	2.5M	476.81K
May 06, 2022	KEATING LAURIE	PURCHASE	12.00	4.17K	49.99K	4.17K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE9.58M2

SALES00

NET SHARES9.58M2

SHARES HELD23.51M2

% NET SHARES-59.27%0%

Frequently Asked Questions

Stock Outstanding Shares

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares3.46

Short Percent Of Float6.54

Shares Outstanding32.80M

Shares Float14.53M

Shares Short1.13M

Short Ratio3.54

6.54%

Short % of Float

3.46%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

0.27% Percentage of Shares held by All Insiders

89.5% Percentage of Shares held by All Institutions

89.74% Percentage of Float held by Institutions

Number of Institutions Holding Shares

Institutional Ownership

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Sep 30, 2025	CITIGROUP INC	0%	1.49K	6.9K	-5.11K	-77.37%
Sep 30, 2025	JPMORGAN CHASE & CO	0.01%	2.18K	10.05K	-8.66K	-79.93%
Sep 30, 2025	FMR LLC	0.01%	2.43K	11.23K	-3.17K	-56.63%
Sep 30, 2025	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.02%	5.75K	26.56K	-823	-12.52%
Sep 30, 2025	NORTHERN TRUST CORP	0.18%	59.53K	275.01K	11.54K	+24.05%
Sep 30, 2025	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.12%	38.08K	175.93K	38.08K	+100.00%
Sep 30, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	0.11%	36.84K	170.21K	16.49K	+81.02%
Sep 30, 2025	DIMENSIONAL FUND ADVISORS LP	0.1%	33.01K	152.52K	-6.69K	-16.86%
Sep 30, 2025	RATHBONES GROUP PLC	0.1%	32K	147.85K	0	0
Sep 30, 2025	CUBIST SYSTEMATIC STRATEGIES, LLC	0.09%	30.67K	141.7K	30.67K	+100.00%
Sep 30, 2025	FIFTH LANE CAPITAL, LP	0.21%	70K	323.4K	70K	+100.00%
Sep 30, 2025	BANK OF MONTREAL /CAN/	0.06%	20K	92.41K	20K	+100.00%
Sep 30, 2025	MILITIA CAPITAL PARTNERS, LP	0.05%	15.5K	71.61K	15.5K	+100.00%
Sep 30, 2025	HEIGHTS CAPITAL MANAGEMENT, INC	0.03%	10K	46.2K	10K	+100.00%
Sep 30, 2025	LOGOS GLOBAL MANAGEMENT LP	2.29%	750K	3.47M	750K	+100.00%
Sep 30, 2025	BALYASNY ASSET MANAGEMENT L.P.	4.07%	1.33M	6.16M	1.33M	+100.00%
Sep 30, 2025	RANGELEY CAPITAL, LLC	0.13%	44K	203.28K	9K	+25.71%
Sep 30, 2025	JANUS HENDERSON GROUP PLC	4.58%	1.5M	6.92M	1.5M	+100.00%
Sep 30, 2025	LAURION CAPITAL MANAGEMENT LP	5.78%	1.89M	8.74M	1.08M	+133.38%
Sep 30, 2025	BVF INC/IL	5.85%	1.92M	8.85M	1.92M	+100.00%
Sep 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	6.2%	2.03M	9.38M	-729.17K	-26.43%
Sep 30, 2025	VIVO CAPITAL, LLC	7.1%	2.33M	10.74M	2.33M	+100.00%
Sep 30, 2025	COMMODORE CAPITAL LP	7.2%	2.36M	10.89M	2.36M	+100.00%
Sep 30, 2025	VANGUARD PERSONALIZED INDEXING MANAGEMENT, LLC	0%	0	-	-15.94K	-100.00%
Sep 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0%	0	-	-137	-100.00%
Sep 30, 2025	MARSHALL WACE, LLP	0%	0	-	-39.21K	-100.00%
Sep 30, 2025	GROUP ONE TRADING, L.P.	0%	0	-	-4.04K	-100.00%
Sep 30, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.19%	63K	291.06K	-28.92K	-31.46%
Sep 30, 2025	UBS GROUP AG	0.74%	242.45K	1.12M	229.09K	+1,714.48%
Sep 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	1.47%	481.37K	2.22M	481.37K	+100.00%
Sep 30, 2025	AWM INVESTMENT COMPANY, INC.	3.13%	1.03M	4.74M	1.03M	+100.00%
Sep 30, 2025	RA CAPITAL MANAGEMENT, L.P.	61.27%	20.06M	92.7M	9.38M	+87.70%
Sep 30, 2025	GSA CAPITAL PARTNERS LLP	0.14%	46.16K	213K	46.16K	+100.00%
Sep 30, 2025	RTW INVESTMENTS, LP	4.58%	1.5M	6.93M	1.5M	+100.00%
Sep 30, 2025	BOXER CAPITAL MANAGEMENT, LLC	0.76%	250K	1.16M	250K	+100.00%
Sep 30, 2025	JANE STREET GROUP, LLC	3.34%	1.09M	5.05M	1.09M	+100.00%
Sep 30, 2025	DEEP TRACK CAPITAL, LP	3.66%	1.2M	5.54M	1.2M	+100.00%
Sep 30, 2025	PNC FINANCIAL SERVICES GROUP, INC.	0%	0	-	-35	-100.00%
Sep 30, 2025	STATE STREET CORP	0.2%	65.79K	303.95K	-3.35K	-4.85%
Sep 30, 2025	IKARIAN CAPITAL, LLC	1.64%	535.97K	2.48M	385.97K	+257.31%
Sep 30, 2025	MORGAN STANLEY	1.76%	575.16K	2.66M	510.32K	+787.07%
Sep 30, 2025	SIREN, L.L.C.	2.14%	700K	3.23M	700K	+100.00%
Sep 30, 2025	OCTAGON CAPITAL ADVISORS LP	2.14%	700K	3.23M	700K	+100.00%
Sep 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	4.43%	1.45M	6.7M	100K	+7.41%
Sep 30, 2025	OPALEYE MANAGEMENT INC.	0.23%	75K	346.5K	-165K	-68.75%
Sep 30, 2025	RBF CAPITAL, LLC	0.31%	100K	462K	0	0
Sep 30, 2025	MONIMUS CAPITAL MANAGEMENT, LP	0.32%	104.8K	484.18K	104.8K	+100.00%
Sep 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.4%	131.63K	608.14K	89.33K	+211.15%
Sep 30, 2025	ACADIAN ASSET MANAGEMENT LLC	0.46%	150.19K	693K	150.19K	+100.00%
Sep 30, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.52%	171.47K	792.18K	15K	+9.59%
Sep 30, 2025	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.58%	190.26K	878.98K	190.26K	+100.00%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.61%	200.73K	927.77K	-365	-0.18%
Sep 30, 2025	MONASHEE INVESTMENT MANAGEMENT LLC	0.92%	300K	1.39M	300K	+100.00%
Sep 30, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	0.96%	315K	1.46M	315K	+100.00%
Sep 30, 2025	BOOTHBAY FUND MANAGEMENT, LLC	1.07%	350.39K	1.62M	304.82K	+668.89%
Sep 30, 2025	STEMPOINT CAPITAL LP	1.19%	389.19K	1.8M	389.19K	+100.00%
Sep 30, 2025	BLACKROCK, INC.	1.37%	450.13K	2.08M	-197.9K	-30.54%
Sep 30, 2025	MILLENNIUM MANAGEMENT LLC	1.53%	500.27K	2.31M	-1.01M	-66.85%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0%	0	-	-327	-100.00%
Sep 30, 2025	NISA INVESTMENT ADVISORS, LLC	0%	195	901	-310	-61.39%
Sep 30, 2025	GF FUND MANAGEMENT CO. LTD.	0%	679	3.14K	-129	-15.97%
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.23%	75.7K	349.73K	24.4K	+47.56%
Sep 30, 2025	TCG CROSSOVER MANAGEMENT, LLC	3.66%	1.2M	5.54M	1.2M	+100.00%
Sep 30, 2025	CWM, LLC	0%	767	4K	-2.81K	-78.55%
Sep 30, 2025	BARCLAYS PLC	0%	1.16K	5.34K	-2.55K	-68.79%
Sep 30, 2025	MIRAE ASSET GLOBAL INVESTMENTS CO., LTD.	0%	1.27K	5.86K	4	+0.32%
Sep 30, 2025	VIKING GLOBAL INVESTORS LP	10.63%	3.48M	16.09M	2M	+134.91%
Sep 30, 2025	WOODLINE PARTNERS LP	4%	1.31M	6.06M	619.49K	+89.58%
Sep 30, 2025	VANGUARD GROUP INC	5.4%	1.77M	8.17M	831.33K	+88.72%
Sep 30, 2025	PERCEPTIVE ADVISORS LLC	2.53%	829.87K	3.83M	829.87K	+100.00%
Sep 30, 2025	ECOR1 CAPITAL, LLC	2.44%	800K	3.7M	800K	+100.00%
Sep 30, 2025	TWO SIGMA INVESTMENTS, LP	0.28%	92.49K	427.32K	28.75K	+45.11%
Sep 30, 2025	CITADEL ADVISORS LLC	0.26%	84.4K	389.93K	84.4K	+100.00%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0%	1.4K	6.45K	-7.13K	-83.62%
Jun 30, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	0.06%	20.35K	22.59K	0	0
Jun 30, 2025	SUVRETTA CAPITAL MANAGEMENT, LLC	0.92%	300K	333K	-1.36M	-81.94%
Jun 30, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.48%	156.47K	173.68K	156.47K	+100.00%
Jun 30, 2025	XTX TOPCO LTD	0%	0	-	-18.14K	-100.00%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.61%	201.1K	223.3K	-182.8K	-47.62%
Jun 30, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.28%	91.92K	102.04K	35K	+61.49%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.22%	70.6K	78.37K	30.36K	+75.45%
Jun 30, 2025	STATE STREET CORP	0.21%	69.14K	76.75K	-250.96K	-78.40%
Jun 30, 2025	TWO SIGMA INVESTMENTS, LP	0.19%	63.74K	70.75K	17.55K	+37.98%
Jun 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.16%	51.3K	56.94K	6K	+13.24%
Jun 30, 2025	NORTHERN TRUST CORP	0.15%	47.99K	53.26K	-93.05K	-65.98%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0.03%	10.34K	11.47K	-8.39K	-44.79%
Jun 30, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0.03%	9.57K	10.62K	3.41K	+55.38%
Jun 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.03%	8.52K	9.46K	6.62K	+346.93%
Jun 30, 2025	GF FUND MANAGEMENT CO. LTD.	0%	808	897	0	0
Jun 30, 2025	RANGELEY CAPITAL, LLC	0.11%	35K	38.85K	20K	+133.33%
Jun 30, 2025	VANGUARD GROUP INC	2.86%	937.02K	1.04M	37.29K	+4.14%
Jun 30, 2025	MILLENNIUM MANAGEMENT LLC	4.61%	1.51M	1.68M	476.18K	+46.10%
Jun 30, 2025	MIRAE ASSET GLOBAL INVESTMENTS CO., LTD.	0%	1.26K	1.4K	243	+23.80%
Jun 30, 2025	ROYAL BANK OF CANADA	0%	1.53K	1K	1.53K	+100.00%
Jun 30, 2025	CWM, LLC	0.01%	3.58K	4K	-2.46K	-40.79%
Jun 30, 2025	BARCLAYS PLC	0.01%	3.7K	4K	-18.34K	-83.20%
Jun 30, 2025	JPMORGAN CHASE & CO	0.03%	10.84K	12.03K	780	+7.76%
Jun 30, 2025	UBS GROUP AG	0.04%	13.36K	14.83K	-20.91K	-61.01%
Jun 30, 2025	DIMENSIONAL FUND ADVISORS LP	0.12%	39.7K	44.12K	-14.93K	-27.33%
Jun 30, 2025	RATHBONES GROUP PLC	0.1%	32K	35.52K	0	0
Jun 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0%	0	-	-6.49K	-100.00%
Jun 30, 2025	STRS OHIO	0%	0	-	-10.2K	-100.00%
Jun 30, 2025	DEUTSCHE BANK AG\	0%	0	-	-48.52K	-100.00%
Jun 30, 2025	AMERITAS INVESTMENT PARTNERS, INC.	0%	0	-	-1.18K	-100.00%
Jun 30, 2025	MIRAE ASSET GLOBAL ETFS HOLDINGS LTD.	0%	0	-	-9.29K	-100.00%
Jun 30, 2025	COREBRIDGE FINANCIAL, INC.	0%	0	-	-7.61K	-100.00%
Jun 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0%	137	152	-2.6K	-95.00%
Jun 30, 2025	WELLS FARGO & COMPANY/MN	0%	327	363	-7.31K	-95.72%
Jun 30, 2025	NISA INVESTMENT ADVISORS, LLC	0%	505	561	210	+71.19%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.13%	42.31K	46.96K	-33.3K	-44.05%
Jun 30, 2025	GROUP ONE TRADING, L.P.	0.01%	4.04K	4.48K	-5.86K	-59.20%
Jun 30, 2025	FMR LLC	0.02%	5.6K	6.22K	-14.39K	-71.97%
Jun 30, 2025	CITIGROUP INC	0.02%	6.6K	7.33K	-5.8K	-46.77%
Jun 30, 2025	AQR CAPITAL MANAGEMENT LLC	0.1%	32.71K	36.3K	-54.3K	-62.41%
Jun 30, 2025	ZACKS INVESTMENT MANAGEMENT	0.12%	38.05K	42.23K	0	0
Jun 30, 2025	MARSHALL WACE, LLP	0.12%	39.21K	43.52K	39.21K	+100.00%
Jun 30, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.14%	45.57K	50.58K	0	0
Jun 30, 2025	MORGAN STANLEY	0.2%	64.84K	71.97K	32	+0.05%
Jun 30, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.22%	73K	81.03K	73K	+100.00%
Jun 30, 2025	IKARIAN CAPITAL, LLC	0.46%	150K	166.5K	0	0
Jun 30, 2025	OPALEYE MANAGEMENT INC.	0.73%	240K	266.4K	-180K	-42.86%
Jun 30, 2025	LAURION CAPITAL MANAGEMENT LP	2.48%	810.76K	899.95K	0	0
Jun 30, 2025	VIKING GLOBAL INVESTORS LP	4.53%	1.48M	1.65M	0	0
Jun 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	8.43%	2.76M	3.06M	83.23K	+3.11%
Jun 30, 2025	TRUE WEALTH DESIGN, LLC	0%	0	-	-145	-100.00%
Jun 30, 2025	CORECAP ADVISORS, LLC	0%	0	-	-546	-100.00%
Jun 30, 2025	EVERSOURCE WEALTH ADVISORS, LLC	0%	0	-	-1	-100.00%
Jun 30, 2025	BANK OF NEW YORK MELLON CORP	0%	0	-	-33.47K	-100.00%
Jun 30, 2025	STERLING CAPITAL MANAGEMENT LLC	0%	0	-	-20	-100.00%
Jun 30, 2025	UBS OCONNOR LLC	0%	0	-	-26.56K	-100.00%
Jun 30, 2025	RHUMBLINE ADVISERS	0%	0	-	-19.07K	-100.00%
Jun 30, 2025	ALLIANCEBERNSTEIN L.P.	0%	0	-	-17.65K	-100.00%
Jun 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0%	0	-	-17.63K	-100.00%
Jun 30, 2025	COLDSTREAM CAPITAL MANAGEMENT INC	0%	0	-	-67	-100.00%
Jun 30, 2025	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0%	0	-	-1.13K	-100.00%
Jun 30, 2025	SEI INVESTMENTS CO	0%	0	-	-70.14K	-100.00%
Jun 30, 2025	RBF CAPITAL, LLC	0.31%	100K	111K	100K	+100.00%
Jun 30, 2025		0%	808	897	0	0
Jun 30, 2025	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.02%	6.57K	7.3K	14	+0.21%
Jun 30, 2025	RA CAPITAL MANAGEMENT, L.P.	32.64%	10.69M	11.87M	0	0
Jun 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	4.12%	1.35M	1.5M	0	0
Jun 30, 2025	WOODLINE PARTNERS LP	2.11%	691.53K	767.6K	-89.37K	-11.44%
Jun 30, 2025	BLACKROCK, INC.	1.98%	648.02K	719.3K	-646.23K	-49.93%
Jun 30, 2025	PROSIGHT MANAGEMENT, LP	0.75%	243.98K	270.82K	243.98K	+100.00%
Jun 30, 2025	VANGUARD PERSONALIZED INDEXING MANAGEMENT, LLC	0.05%	15.94K	17.69K	5.34K	+50.37%
Jun 30, 2025	LEGAL & GENERAL GROUP PLC	0%	0	-	-1.68K	-100.00%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0%	0	-	-40.07K	-100.00%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.17%	383.89K	539.5K	11.04K	+2.96%
Mar 31, 2025	STATE STREET CORP	0.98%	320.1K	449.75K	-2.79K	-0.86%
Mar 31, 2025	IKARIAN CAPITAL, LLC	0.46%	150K	210.75K	150K	+100.00%
Mar 31, 2025	MORGAN STANLEY	0.2%	64.81K	91.05K	-488.67K	-88.29%
Mar 31, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.14%	45.57K	64.03K	45.57K	+100.00%
Mar 31, 2025	RA CAPITAL MANAGEMENT, L.P.	32.72%	10.69M	15.02M	0	0
Mar 31, 2025	VANGUARD PERSONALIZED INDEXING MANAGEMENT, LLC	0.03%	10.6K	14.89K	10.6K	+100.00%
Mar 31, 2025	ZACKS INVESTMENT MANAGEMENT	0.12%	38.05K	53.46K	0	0
Mar 31, 2025	RHUMBLINE ADVISERS	0.06%	19.07K	26.79K	117	+0.62%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0.06%	18.72K	26.3K	-35.15K	-65.24%
Mar 31, 2025	CITIGROUP INC	0.04%	12.4K	17.43K	17	+0.14%
Mar 31, 2025	STRS OHIO	0.03%	10.2K	14.33K	0	0
Mar 31, 2025	UBS OCONNOR LLC	0.08%	26.56K	37.32K	26.56K	+100.00%
Mar 31, 2025	BARCLAYS PLC	0.07%	22.04K	31K	-4.37K	-16.54%
Mar 31, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	0.06%	20.35K	28.6K	20.35K	+100.00%
Mar 31, 2025	FMR LLC	0.06%	19.99K	28.09K	19.41K	+3,334.54%
Mar 31, 2025	RATHBONES GROUP PLC	0.1%	32K	44.96K	0	0
Mar 31, 2025	CITADEL ADVISORS LLC	0.06%	19.6K	27.54K	19.6K	+100.00%
Mar 31, 2025	XTX TOPCO LTD	0.06%	18.14K	25.49K	18.14K	+100.00%
Mar 31, 2025	ALLIANCEBERNSTEIN L.P.	0.05%	17.65K	24.8K	0	0
Mar 31, 2025	VIKING GLOBAL INVESTORS LP	4.54%	1.48M	2.08M	0	0
Mar 31, 2025	BANK OF NEW YORK MELLON CORP	0.1%	33.47K	47.02K	-20	-0.06%
Mar 31, 2025	NORTHERN TRUST CORP	0.43%	141.04K	198.16K	-16K	-10.19%
Mar 31, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.05%	17.63K	24.77K	17.63K	+100.00%
Mar 31, 2025		0.05%	15K	21.08K	15K	+100.00%
Mar 31, 2025	VANGUARD GROUP INC	2.75%	899.73K	1.26M	-12.94K	-1.42%
Mar 31, 2025	LAURION CAPITAL MANAGEMENT LP	2.48%	810.76K	1.14M	0	0
Mar 31, 2025	WOODLINE PARTNERS LP	2.39%	780.9K	1.1M	780.9K	+100.00%
Mar 31, 2025	OPALEYE MANAGEMENT INC.	1.29%	420K	590.1K	310K	+281.82%
Mar 31, 2025	JPMORGAN CHASE & CO	0.03%	10.06K	14.13K	-21.23K	-67.86%
Mar 31, 2025	GROUP ONE TRADING, L.P.	0.03%	9.9K	13.91K	9.9K	+100.00%
Mar 31, 2025	MIRAE ASSET GLOBAL ETFS HOLDINGS LTD.	0.03%	9.29K	13.05K	390	+4.38%
Mar 31, 2025	POINT72 ASSET MANAGEMENT, L.P.	8.19%	2.68M	3.76M	2.68M	+100.00%
Mar 31, 2025	SUVRETTA CAPITAL MANAGEMENT, LLC	5.08%	1.66M	2.33M	486.61K	+41.44%
Mar 31, 2025	BLACKROCK, INC.	3.96%	1.29M	1.82M	8.13K	+0.63%
Mar 31, 2025	AQR CAPITAL MANAGEMENT LLC	0.27%	87K	122.24K	87K	+100.00%
Mar 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.23%	75.61K	106.23K	75.61K	+100.00%
Mar 31, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	4.13%	1.35M	1.9M	550K	+68.75%
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	3.16%	1.03M	1.45M	876.38K	+559.50%
Mar 31, 2025	SEI INVESTMENTS CO	0.21%	70.14K	98.55K	70.14K	+100.00%
Mar 31, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.17%	56.92K	79.98K	-41.98K	-42.44%
Mar 31, 2025	DIMENSIONAL FUND ADVISORS LP	0.17%	54.63K	76.86K	-2.47K	-4.33%
Mar 31, 2025	DEUTSCHE BANK AG\	0.15%	48.52K	68.41K	3.78K	+8.46%
Mar 31, 2025	TWO SIGMA INVESTMENTS, LP	0.14%	46.19K	64.9K	46.19K	+100.00%
Mar 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0.14%	45.3K	63.65K	45.3K	+100.00%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.12%	40.24K	56.54K	-58.1K	-59.08%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.12%	40.07K	56.3K	-8.28K	-17.13%
Mar 31, 2025	UBS GROUP AG	0.1%	34.27K	48.15K	22.25K	+185.19%
Mar 31, 2024	CRESTLINE MANAGEMENT, LP	0.15%	35K	514.5K	35K	+100.00%
Mar 31, 2024	AMALGAMATED BANK	0%	337	5K	-876	-72.22%
Mar 31, 2024	METROPOLITAN LIFE INSURANCE CO/NY	0%	596	8.76K	596	+100.00%
Mar 31, 2024	LEGAL & GENERAL GROUP PLC	0%	853	12.54K	0	0
Mar 31, 2024	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0%	1.01K	14.85K	-644	-38.94%
Mar 31, 2024	AMERITAS INVESTMENT PARTNERS, INC.	0%	1.18K	17.27K	0	0
Mar 31, 2024	ACADIAN ASSET MANAGEMENT LLC	0.01%	2.05K	30K	2.05K	+100.00%
Mar 31, 2024	WELLS FARGO & COMPANY/MN	0.01%	3.48K	51.1K	502	+16.88%
Mar 31, 2024	STRS OHIO	0.02%	3.6K	52K	1.7K	+89.47%
Mar 31, 2024	DEUTSCHE BANK AG\	0.02%	4.23K	62.17K	4.23K	+100.00%
Mar 31, 2024	AMERICAN INTERNATIONAL GROUP, INC.	0.02%	4.95K	72.81K	-43	-0.86%
Mar 31, 2024	METLIFE INVESTMENT MANAGEMENT, LLC	0.02%	5.79K	85.17K	5.79K	+100.00%
Mar 31, 2024	NEW YORK STATE COMMON RETIREMENT FUND	0.03%	6.48K	95K	-3	-0.05%
Mar 31, 2024	BARCLAYS PLC	0.03%	7K	103K	-6.72K	-48.97%
Mar 31, 2024	UBS GROUP AG	0.04%	10.06K	147.84K	-857	-7.85%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.06%	13.85K	203.57K	0	0
Mar 31, 2024	RHUMBLINE ADVISERS	0.06%	13.85K	203.6K	10	+0.07%
Mar 31, 2024	JPMORGAN CHASE & CO	0.07%	15.48K	227.59K	5.34K	+52.64%
Mar 31, 2024	AMERICAN CENTURY COMPANIES INC	0.07%	16.7K	245.52K	16.7K	+100.00%
Mar 31, 2024	QUBE RESEARCH & TECHNOLOGIES LTD	0.1%	24.79K	364.35K	24.66K	+20,051.22%
Mar 31, 2024	MORGAN STANLEY	0.12%	28.48K	418.69K	-7.44K	-20.70%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.13%	30.76K	452.17K	-658	-2.09%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.13%	31.29K	459.96K	3.5K	+12.59%
Mar 31, 2024	RATHBONES GROUP PLC	0.13%	32K	470.44K	-30K	-48.38%
Mar 31, 2024	CITIGROUP INC	0.17%	40.61K	596.97K	39.24K	+2,864.23%
Mar 31, 2024	LAURION CAPITAL MANAGEMENT LP	3.54%	841.43K	12.37M	176.92K	+26.62%
Mar 31, 2024	JANUS HENDERSON GROUP PLC	4.9%	1.17M	17.23M	178.44K	+18.06%
Mar 31, 2024	ADAGE CAPITAL PARTNERS GP, L.L.C.	5.6%	1.33M	19.6M	233.61K	+21.24%
Mar 31, 2024	PERCEPTIVE ADVISORS LLC	5.93%	1.41M	20.73M	1.41M	+100.00%
Mar 31, 2024	VIKING GLOBAL INVESTORS LP	6.23%	1.48M	21.79M	0	0
Mar 31, 2024	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	6.32%	1.5M	22.09M	1.5M	+100.00%
Mar 31, 2024	SUVRETTA CAPITAL MANAGEMENT, LLC	6.39%	1.52M	22.36M	1.03M	+212.56%
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	0.05%	12.06K	177.28K	0	0
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.06%	13.21K	194.23K	-943	-6.66%
Mar 31, 2024	WALLEYE CAPITAL LLC	0.27%	64.61K	949.83K	64.61K	+100.00%
Mar 31, 2024	MONASHEE INVESTMENT MANAGEMENT LLC	0.36%	85.89K	1.26M	85.89K	+100.00%
Mar 31, 2024	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.42%	99.2K	1.46M	0	0
Mar 31, 2024	SUPERSTRING CAPITAL MANAGEMENT LP	0.48%	114.39K	1.68M	114.39K	+100.00%
Mar 31, 2024	POINT72 ASSET MANAGEMENT, L.P.	0.81%	192.18K	2.83M	192.18K	+100.00%
Mar 31, 2024	ARTAL GROUP S.A.	0.84%	200K	2.94M	200K	+100.00%
Mar 31, 2024	STATE STREET CORP	1.01%	240.98K	3.54M	24.07K	+11.10%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	1.26%	299.49K	4.4M	89.43K	+42.58%
Mar 31, 2024	OCTAGON CAPITAL ADVISORS LP	1.58%	376.12K	5.53M	376.12K	+100.00%
Mar 31, 2024	SOFINNOVA INVESTMENTS, INC.	2.12%	503.62K	7.4M	480.59K	+2,086.06%
Mar 31, 2024	ZURCHER KANTONALBANK (ZURICH CANTONALBANK)	0%	1	15	0	0
Mar 31, 2024	NELSON, VAN DENBURG & CAMPBELL WEALTH MANAGEMENT GROUP, LLC	0%	2	29	2	+100.00%
Mar 31, 2024	NISA INVESTMENT ADVISORS, LLC	0%	9	132	9	+100.00%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.08%	19.06K	280.14K	3.27K	+20.69%
Mar 31, 2024	NORTHERN TRUST CORP	0.39%	92.2K	1.36M	17.37K	+23.21%
Mar 31, 2024	FMR LLC	1.93%	458.64K	6.74M	-279.38K	-37.86%
Mar 31, 2024	BLACKROCK INC.	3.28%	781.44K	11.49M	57.9K	+8.00%
Mar 31, 2024	VANGUARD GROUP INC	3.57%	850.45K	12.5M	344.27K	+68.01%
Mar 31, 2024	RA CAPITAL MANAGEMENT, L.P.	44.92%	10.69M	157.14M	2.56M	+31.45%
Dec 31, 2023	AMERICAN INTERNATIONAL GROUP, INC.	0.02%	5K	33.97K	-20	-0.40%
Dec 31, 2023	JPMORGAN CHASE & CO	0.04%	10.14K	68.97K	-818	-7.46%
Dec 31, 2023	UBS GROUP AG	0.05%	10.91K	74.22K	5.76K	+111.92%
Dec 31, 2023	JANE STREET GROUP, LLC	0.05%	11.23K	76.35K	11.23K	+100.00%
Dec 31, 2023	ALLIANCEBERNSTEIN L.P.	0.05%	12.06K	82.01K	0	0
Dec 31, 2023	BARCLAYS PLC	0.06%	13.72K	93K	12.1K	+743.00%
Dec 31, 2023	RHUMBLINE ADVISERS	0.06%	13.84K	94.11K	-808	-5.52%
Dec 31, 2023	NUVEEN ASSET MANAGEMENT, LLC	0.06%	13.85K	94.17K	0	0
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.06%	14.16K	96.26K	14.16K	+100.00%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.07%	15.79K	107.37K	-2.22K	-12.31%
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	0.08%	19.81K	134.69K	3.5K	+21.43%
Dec 31, 2023	SOFINNOVA INVESTMENTS, INC.	0.1%	23.04K	156.66K	23.04K	+100.00%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.12%	27.79K	188.97K	0	0
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.13%	31.42K	213.64K	20	+0.06%
Dec 31, 2023	MORGAN STANLEY	0.15%	35.92K	244.24K	25.99K	+261.63%
Dec 31, 2023	RATHBONES GROUP PLC	0.26%	62K	421.62K	0	0
Dec 31, 2023	NORTHERN TRUST CORP	0.31%	74.83K	508.81K	90	+0.12%
Dec 31, 2023	NEW YORK STATE COMMON RETIREMENT FUND	0.03%	6.48K	44K	-31	-0.48%
Dec 31, 2023	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.42%	99.2K	674.56K	42.9K	+76.20%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	0.88%	210.05K	1.43M	10.78K	+5.41%
Dec 31, 2023	STATE STREET CORP	0.91%	216.91K	1.48M	-2.21K	-1.01%
Dec 31, 2023	SAMSARA BIOCAPITAL, LLC	1.84%	436.81K	2.97M	-214.24K	-32.91%
Dec 31, 2023	SUVRETTA CAPITAL MANAGEMENT, LLC	2.05%	486.61K	3.31M	0	0
Dec 31, 2023	VANGUARD GROUP INC	2.13%	506.18K	3.44M	3.39K	+0.67%
Dec 31, 2023	LAURION CAPITAL MANAGEMENT LP	2.79%	664.52K	4.52M	0	0
Dec 31, 2023	BLACKROCK INC.	3.04%	723.54K	4.92M	-111.73K	-13.38%
Dec 31, 2023	FMR LLC	3.1%	738.02K	5.02M	-1.63M	-68.81%
Dec 31, 2023	JANUS HENDERSON GROUP PLC	4.15%	988.2K	6.74M	988.2K	+100.00%
Dec 31, 2023	ADAGE CAPITAL PARTNERS GP, L.L.C.	4.62%	1.1M	7.48M	420K	+61.76%
Dec 31, 2023	VIKING GLOBAL INVESTORS LP	6.23%	1.48M	10.08M	0	0
Dec 31, 2023	RA CAPITAL MANAGEMENT, L.P.	34.18%	8.13M	55.3M	0	0
Dec 31, 2023	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0%	0	-	-615	-100.00%
Dec 31, 2023	ALLSPRING GLOBAL INVESTMENTS HOLDINGS, LLC	0%	0	-	-6.56K	-100.00%
Dec 31, 2023	RENAISSANCE TECHNOLOGIES LLC	0%	0	-	-10K	-100.00%
Dec 31, 2023	NISA INVESTMENT ADVISORS, LLC	0%	0	-	-1.4K	-100.00%
Dec 31, 2023	ZURCHER KANTONALBANK (ZURICH CANTONALBANK)	0%	1	7	-1.31K	-99.92%
Dec 31, 2023	QUBE RESEARCH & TECHNOLOGIES LTD	0%	123	836	-1K	-89.06%
Dec 31, 2023	LEGAL & GENERAL GROUP PLC	0%	853	5.8K	-285	-25.04%
Dec 31, 2023	AMERITAS INVESTMENT PARTNERS, INC.	0%	1.18K	7.99K	0	0
Dec 31, 2023	AMALGAMATED BANK	0.01%	1.21K	8K	-162	-11.78%
Dec 31, 2023	CITIGROUP INC	0.01%	1.37K	9.32K	1.07K	+355.15%
Dec 31, 2023	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0.01%	1.65K	11.25K	-564	-25.43%
Dec 31, 2023	TOWER RESEARCH CAPITAL LLC (TRC)	0.01%	1.76K	11.97K	-2.23K	-55.88%
Dec 31, 2023	STRS OHIO	0.01%	1.9K	12K	0	0
Dec 31, 2023	WELLS FARGO & COMPANY/MN	0.01%	2.97K	20.22K	606	+25.59%
Dec 31, 2023	ROYAL BANK OF CANADA	0.01%	3.18K	22K	1.52K	+91.27%

Insiders

Insiders	Designation	Shares Held
RA CAPITAL MANAGEMENT, L.P.		18.55M
OXFORD SCIENCE ENTERPRISES PLC	Former 10% Owner	4.96M
SHAH RAJEEV M.		1.3M
FLYNN JAMES E	Possible Member of 10% Group	476.81K
DEERFIELD PRIVATE DESIGN FUND V, L.P.		476.81K
MCARTHUR JAMES G	President and CEO	113.91K
STRECK PAUL	EVP, Head of R&D	27.81K
KEATING LAURIE	director	4.17K
DONNELLY NOEL	Chief Financial Officer	1.67K
DELENA MARY BETH	General Counsel	1.57K
MELLION MICHELLE L	Chief Medical Officer	0
SVENSTRUP NIELS	SVP, Chem. Mfg & Controls	0
GOYAL JAYA	EVP, Res. & Preclin. Dev.	0

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Sep 30, 2025	OXFORD SCIENCE ENTERPRISES PLC	PURCHASE	3.20	200K	640K	4.96M
Sep 26, 2025	RA CAPITAL MANAGEMENT, L.P.	PURCHASE	3.20	9.38M	30M	18.55M
May 30, 2025	STRECK PAUL	PURCHASE	1.24	8.38K	10.39K	27.81K
Apr 17, 2025	MCARTHUR JAMES G	PURCHASE	1.35	10K	13.55K	113.91K
Apr 08, 2025	MCARTHUR JAMES G	PURCHASE	1.15	41.5K	47.73K	103.91K
Feb 26, 2025	DELENA MARY BETH	SALE	1.68	1.43K	2.41K	1.57K
Feb 26, 2025	DONNELLY NOEL	SALE	1.68	1.53K	2.57K	1.67K
Jul 25, 2024	MELLION MICHELLE L	SALE	18.06	7.57K	136.74K	0
Jul 24, 2024	MELLION MICHELLE L	SALE	18.01	201	3.62K	0
Jul 18, 2024	MELLION MICHELLE L	SALE	18.20	12.63K	229.8K	0
Jul 16, 2024	MELLION MICHELLE L	SALE	18.00	5.9K	106.25K	0
Jul 12, 2024	MELLION MICHELLE L	SALE	18.04	3.29K	59.33K	0
Jul 02, 2024	MELLION MICHELLE L	SALE	18.07	37	668.59	0
Jul 01, 2024	MELLION MICHELLE L	SALE	18.01	875	15.76K	0
Jun 24, 2024	MELLION MICHELLE L	SALE	18.19	9.26K	168.43K	0
Jun 12, 2024	MELLION MICHELLE L	SALE	18.06	1.09K	19.61K	0
Jun 11, 2024	MELLION MICHELLE L	SALE	18.04	500	9.02K	0
Jun 06, 2024	MELLION MICHELLE L	SALE	18.00	1.41K	25.4K	0
Jun 05, 2024	MELLION MICHELLE L	SALE	18.09	7.25K	131.06K	0
May 17, 2024	SVENSTRUP NIELS	SALE	13.41	10K	134.1K	0
Feb 09, 2024	RA CAPITAL MANAGEMENT, L.P.	PURCHASE	10.64	2.56M	27.21M	9.18M
Nov 30, 2023	MCARTHUR JAMES G	PURCHASE	4.17	1.69K	7.06K	1.69K
Jun 08, 2023	MCARTHUR JAMES G	SALE	16.04	2.38K	38.19K	0
Jun 07, 2023	MCARTHUR JAMES G	SALE	16.23	8.42K	136.62K	0
Jun 06, 2023	MCARTHUR JAMES G	SALE	16.18	18.15K	293.66K	0
Jun 05, 2023	MCARTHUR JAMES G	SALE	16.06	500	8.03K	0
Jun 02, 2023	MCARTHUR JAMES G	SALE	16.04	1.8K	28.86K	0
Mar 24, 2023	GOYAL JAYA	SALE	20.00	392	7.84K	0
Feb 08, 2023	GOYAL JAYA	SALE	17.00	644	10.95K	0
Feb 07, 2023	GOYAL JAYA	SALE	17.18	3.68K	63.21K	0
Feb 06, 2023	GOYAL JAYA	SALE	17.04	1.68K	28.57K	0
May 10, 2022	OXFORD SCIENCE ENTERPRISES PLC	PURCHASE	12.00	879.97K	10.56M	4.76M
May 10, 2022	RA CAPITAL MANAGEMENT, L.P.	PURCHASE	12.00	249.75K	3M	1.3M
May 10, 2022	SHAH RAJEEV M.	PURCHASE	12.00	249.75K	3M	1.3M
May 10, 2022	FLYNN JAMES E	PURCHASE	12.00	208.33K	2.5M	476.81K
May 10, 2022	DEERFIELD PRIVATE DESIGN FUND V, L.P.	PURCHASE	12.00	208.33K	2.5M	476.81K
May 06, 2022	KEATING LAURIE	PURCHASE	12.00	4.17K	49.99K	4.17K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE9.58M2

SALES00

NET SHARES9.58M2

SHARES HELD23.51M2

% NET SHARES-59.27%0%

PEPG Stock Ownership Breakdown

PepGen

Stock Outstanding Shares

Market Insider

Institutional Ownership

Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions

Stock Outstanding Shares

Market Insider

Institutional Ownership

Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions