How many institutions own PCVX stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own PCVX shares is 421, representing 114.93% of the company's common stock.

Who are the major shareholders selling Vaxcyte, Inc. stock?

PICTET ASSET MANAGEMENT HOLDING SA, in the last quarter, reduced its stake in PCVX by -14.39% restricting it's holding to 881.44 thousand shares of worth nearly $40.67M. BANQUE PICTET & CIE SA also lessened -4.07% of the PCVX shares from its portfolio, reducing its holding to 71.82 thousand shares of worth $3.31M. JUMP FINANCIAL, LLC also shunned PCVX shares holding by -53.14% last quarter which brought its holding to 89.82 thousand shares worth $4.14M.

Investors who are buying PCVX stock?

As per its latest 13F filing, UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH increased its stake in PCVX by 105.34% in the last quarter. The institutional holder raised its holding to 70.12 thousand shares having worth more than $3.24M. SWISS NATIONAL BANK also added 2.35% more shares of PCVX to its portfolio, raising its holding to 230.4 thousand shares of worth $10.63M. FRANKLIN RESOURCES INC also increased its PCVX shares holding by 0.01% which brought its holding to 336.14 thousand shares worth $15.51M.

PCVX's major insiders: who are they?

The insider with the most stakes in PCVX is Wassil Jim , CHIEF OPERATING OFFICER at the company. Additionally, PCVX stock is highly held by CHIEF EXECUTIVE OFFICER PICKERING GRANT and PRESIDENT AND CFO GUGGENHIME ANDREW among others.

Did an insider recently sell PCVX stock?

Company executives, directors, and other insiders own 0.66% percent of Vaxcyte, Inc.'s stock. Within the last six months, there have been 8 transaction(s) in which PCVX insiders have sold stock, totaling 30.42K shares. Insiders that have sold shares include WASSIL JIM, COWAN ELVIA, and DHALIWAL HARPREET S..

Which insider recently purchased PCVX stock?

There have been 0 transaction(s) during the past 6-months in which Vaxcyte, Inc. insiders have bought stock, totalling 0 shares

How much of PCVX does insiders own?

Around 617.84K Vaxcyte, Inc. shares are held by insiders, which represents about 0.66% of PCVX stock.

Who is the insider with the largest stake?

PCVX CHIEF OPERATING OFFICER, Wassil Jim holds the largest portfolio of the company's shares. PCVX shares owned by Wassil total nearly 160.74 thousand.

Which institution holds the most shares in PCVX?

PICTET ASSET MANAGEMENT HOLDING SA is the largest institutional owner in PCVX which holds 881.44 thousand shares worth $40.67M or 0.65% of the total PCVX shares outstanding followed by UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH with ownership of 70.12 thousand shares representing 0.05% of the PCVX ownership. BANQUE PICTET & CIE SA is the third largest stakeholder with 71.82 thousand shares or 0.05% of the ownership worth more than $3.31M.

Is Vaxcyte, Inc. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the PCVX is concerned, it is a stock which is optionable.

Is there a short position on PCVX's shares?

Number of PCVX shares short is 11.44M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding PCVX shares are there?

As of today, 129.82M shares of PCVX are outstanding.

Is there many float in PCVX stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, PCVX has 116.97M shares in float.

PCVX short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for PCVX is 8.72.

Vaxcyte (PCVX) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares8.81

Short Percent Of Float9.86

Shares Outstanding129.82M

Shares Float116.97M

Shares Short11.44M

Short Ratio8.72

9.86%

Short % of Float

8.81%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

0.66% Percentage of Shares held by All Insiders

114.93% Percentage of Shares held by All Institutions

115.69% Percentage of Float held by Institutions

421

Number of Institutions Holding Shares

Institutional Ownership

About 114.93% of PCVX shares are held by financial institutions. PICTET ASSET MANAGEMENT HOLDING SA is the top corporate investor, holding 881.44K shares valued at $40.67M. A 0.65% stake in Vaxcyte, Inc. is owned by the company. UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH owns 70.12K shares valued at $3.24M, which translates its holding of 0.05% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Dec 31, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.65%	881.44K	40.67M	-148.19K	-14.39%
Dec 31, 2025	UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH	0.05%	70.12K	3.24M	35.97K	+105.34%
Dec 31, 2025	BANQUE PICTET & CIE SA	0.05%	71.82K	3.31M	-3.05K	-4.07%
Dec 31, 2025	JUMP FINANCIAL, LLC	0.07%	89.82K	4.14M	-101.88K	-53.14%
Dec 31, 2025	SWISS NATIONAL BANK	0.17%	230.4K	10.63M	5.3K	+2.35%
Dec 31, 2025	CITIGROUP INC	0.18%	241.88K	11.16M	-71.2K	-22.74%
Dec 31, 2025	JANE STREET GROUP, LLC	0.21%	279.6K	12.9B	-64.09K	-18.65%
Dec 31, 2025	BARCLAYS PLC	0.22%	296.2K	13.67M	-97.72K	-24.81%
Dec 31, 2025	NUVEEN, LLC	0.23%	307.2K	14.17M	-177.44K	-36.61%
Dec 31, 2025	FRANKLIN RESOURCES INC	0.25%	336.14K	15.51M	37	+0.01%
Dec 31, 2025	DEUTSCHE BANK AG\	0.25%	342.89K	15.82M	-54.9K	-13.80%
Dec 31, 2025	TD ASSET MANAGEMENT INC	0.27%	363.73K	16.78M	-34.75K	-8.72%
Dec 31, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.29%	389.01K	17.95M	-9.13K	-2.29%
Dec 31, 2025	BANK OF NEW YORK MELLON CORP	0.33%	449.36K	20.73M	9.75K	+2.22%
Dec 31, 2025	ECOR1 CAPITAL, LLC	0.33%	450K	20.76M	450K	+100.00%
Dec 31, 2025	FEDERATED HERMES, INC.	0.38%	523.49K	24.15M	505.33K	+2,783.28%
Dec 31, 2025	ENSIGN PEAK ADVISORS, INC	0.39%	527.69K	24.35M	-1.17K	-0.22%
Dec 31, 2025	ASSENAGON ASSET MANAGEMENT S.A.	0.4%	544.73K	25.13M	324.78K	+147.66%
Dec 31, 2025	MORGAN STANLEY	0.61%	835.39K	38.54M	50.9K	+6.49%
Dec 31, 2025	CAPITAL RESEARCH GLOBAL INVESTORS	0.62%	842.98K	38.9M	0	0
Dec 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.95%	1.29M	59.7M	423	+0.03%
Dec 31, 2025	MAVERICK CAPITAL LTD	0.99%	1.35M	62.48M	64.67K	+5.01%
Dec 31, 2025	PIVOTAL BIOVENTURE PARTNERS INVESTMENT ADVISOR LLC	1.01%	1.37M	63.32M	0	0
Dec 31, 2025	POLAR CAPITAL HOLDINGS PLC	1.23%	1.67M	77.18M	1.26M	+302.57%
Dec 31, 2025	CALIGAN PARTNERS LP	1.25%	1.7M	78.66M	1.7M	+100.00%
Dec 31, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	1.27%	1.73M	79.59M	1.39M	+418.02%
Dec 31, 2025	KYNAM CAPITAL MANAGEMENT, LP	2.15%	2.92M	134.84M	-149.25K	-4.86%
Dec 31, 2025	D. E. SHAW & CO., INC.	2.67%	3.63M	167.54M	-659.74K	-15.38%
Dec 31, 2025	PARADIGM BIOCAPITAL ADVISORS LP	2.99%	4.07M	187.7M	283.27K	+7.48%
Dec 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	4.38%	5.97M	275.29M	933.54K	+18.55%
Dec 31, 2025	RA CAPITAL MANAGEMENT, L.P.	7.87%	10.72M	494.83M	-1.24M	-10.37%
Dec 31, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	8.29%	11.3M	521.21M	2.98M	+35.85%
Dec 31, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.37%	497.74K	22.97M	369.01K	+286.65%
Dec 31, 2025	VICTORY CAPITAL MANAGEMENT INC	0.4%	549.51K	25.35M	234.62K	+74.51%
Dec 31, 2025	BROWN ADVISORY INC	0.42%	566.93K	26.16M	-110.06K	-16.26%
Dec 31, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	0.45%	608.96K	28.1M	608.96K	+100.00%
Dec 31, 2025	JENNISON ASSOCIATES LLC	0.5%	677.55K	31.26M	-493.35K	-42.13%
Dec 31, 2025		0.29%	400.36K	18.47M	400.36K	+100.00%
Dec 31, 2025	SATURN V CAPITAL MANAGEMENT LLC	0.59%	798.94K	36.86M	10.5K	+1.33%
Dec 31, 2025	NOVO HOLDINGS A/S	0.67%	916.16K	42.27M	0	0
Dec 31, 2025	EVENTIDE ASSET MANAGEMENT, LLC	0.67%	917.12K	42.31M	537.79K	+141.77%
Dec 31, 2025	ABRDN PLC	0.72%	979.77K	45.21M	256.97K	+35.55%
Dec 31, 2025	NORTHERN TRUST CORP	0.76%	1.03M	47.72M	-39.17K	-3.65%
Dec 31, 2025	GOLDMAN SACHS GROUP INC	0.79%	1.08M	49.74M	102.74K	+10.53%
Dec 31, 2025	JPMORGAN CHASE & CO	0.8%	1.09M	50.09M	-479.52K	-30.64%
Dec 31, 2025	UBS GROUP AG	0.8%	1.09M	50.46M	246.02K	+29.03%
Dec 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	0.86%	1.18M	54.23M	-513.14K	-30.39%
Dec 31, 2025	EVERSEPT PARTNERS, LP	0.88%	1.2M	55.26M	-224.26K	-15.77%
Dec 31, 2025	JANUS HENDERSON GROUP PLC	9.83%	13.39M	617.73M	282.99K	+2.16%
Dec 31, 2025	FMR LLC	10.16%	13.83M	638.32M	1.32M	+10.59%
Dec 31, 2025	NORGES BANK	0.9%	1.23M	56.7M	1.23M	+100.00%
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.1%	2.87M	132.27M	-17.74K	-0.61%
Dec 31, 2025	WESTFIELD CAPITAL MANAGEMENT CO LP	2.6%	3.54M	163.32M	-193K	-5.17%
Dec 31, 2025	PROFUND ADVISORS LLC	0.04%	50.45K	2.33M	17.53K	+53.23%
Dec 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.04%	50.76K	2.34M	-206.91K	-80.30%
Dec 31, 2025	ENVESTNET ASSET MANAGEMENT INC	0.04%	50.8K	2.34M	-19.01K	-27.24%
Dec 31, 2025	DEEP TRACK CAPITAL, LP	2.94%	4M	184.56M	1M	+33.33%
Dec 31, 2025	STATE STREET CORP	3.66%	4.98M	229.78M	194.12K	+4.06%
Dec 31, 2025	BLACKROCK, INC.	7.52%	10.25M	472.77M	290.4K	+2.92%
Dec 31, 2025	VANGUARD GROUP INC	8.95%	12.19M	562.63M	-126.47K	-1.03%
Dec 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.07%	93.3K	4.3B	6.1K	+7.00%
Dec 31, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.08%	108.45K	4.97M	-28.43K	-20.77%
Dec 31, 2025	TWO SIGMA INVESTMENTS, LP	0.08%	111.31K	5.14B	3.72K	+3.46%
Dec 31, 2025	HRT FINANCIAL LP	0.08%	113.95K	5.26M	-84	-0.07%
Dec 31, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.09%	116.82K	5.39M	-4.97K	-4.08%
Dec 31, 2025	LEGAL & GENERAL GROUP PLC	0.09%	120.3K	5.55M	-10.1K	-7.75%
Dec 31, 2025	WELLS FARGO & COMPANY/MN	0.1%	134.08K	6.19M	8.03K	+6.37%
Dec 31, 2025	NAN FUNG TRINITY (HK) LTD	0.1%	142.93K	6.59M	38.68K	+37.10%
Dec 31, 2025	CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM	0.11%	144.6K	6.67M	-11	-0.01%
Dec 31, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.04%	58.23K	2.69M	-9.72K	-14.31%
Dec 31, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.11%	148.79K	6.87M	-165.55K	-52.67%
Dec 31, 2025	RHUMBLINE ADVISERS	0.11%	150.92K	6.96B	-32.29K	-17.63%
Dec 31, 2025	RAYMOND JAMES FINANCIAL INC	0.14%	185.85K	8.45M	-3.44K	-1.82%
Dec 31, 2025	DIMENSIONAL FUND ADVISORS LP	0.14%	191.79K	8.85M	163.42K	+576.09%
Dec 31, 2025	C WORLDWIDE GROUP HOLDING A/S	0.14%	195K	9M	0	0
Dec 31, 2025	CITADEL ADVISORS LLC	0.24%	326.57K	15.07B	120.78K	+58.69%
Dec 31, 2025	MILLENNIUM MANAGEMENT LLC	0.31%	424.29K	19.58M	-524.67K	-55.29%
Dec 31, 2025	LOGOS GLOBAL MANAGEMENT LP	0.48%	650K	29.99M	25K	+4.00%
Dec 31, 2025	BANK OF AMERICA CORP /DE/	0.52%	701.63K	32.37M	66.56K	+10.48%
Dec 31, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.05%	63.81K	2.94M	-2.76K	-4.14%
Dec 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0.05%	65.21K	3.01M	-15.27K	-18.97%
Dec 31, 2025	SEGALL BRYANT & HAMILL, LLC	0.14%	193.42K	8.92M	8.63K	+4.67%
Dec 31, 2025	ALYESKA INVESTMENT GROUP, L.P.	0.18%	244.78K	11.29M	0	0
Dec 31, 2025	UNIVERSITY OF WISCONSIN FOUNDATION	0.18%	247K	11.4M	247K	+100.00%
Dec 31, 2025	AMERICAN CENTURY COMPANIES INC	0.26%	357.3K	16.49M	13.27K	+3.86%
Sep 30, 2025	FIERA CAPITAL CORP	0.25%	345.85K	12.46M	-7.99K	-2.26%
Sep 30, 2025	AMERIPRISE FINANCIAL INC	0.28%	374.9K	13.5M	44.23K	+13.38%
Sep 30, 2025	CAPITAL RESEARCH GLOBAL INVESTORS	0.62%	842.98K	30.36M	-3.93M	-82.33%
Sep 30, 2025	FRANKLIN RESOURCES INC	0.25%	336.11K	12.11M	-603.17K	-64.22%
Sep 30, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.29%	398.14K	14.34M	-156.86K	-28.26%
Sep 30, 2025	TD ASSET MANAGEMENT INC	0.29%	398.48K	14.35M	-141.3K	-26.18%
Sep 30, 2025	POLAR CAPITAL HOLDINGS PLC	0.31%	415.53K	14.97M	-410.27K	-49.68%
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.32%	439.61K	15.83M	-10.08K	-2.24%
Sep 30, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	0.35%	474.41K	17.09M	0	0
Sep 30, 2025	ENSIGN PEAK ADVISORS, INC	0.39%	528.85K	19.05M	-3.35K	-0.63%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.47%	635.07K	22.88M	-447.6K	-41.34%
Sep 30, 2025	BAKER BROS. ADVISORS LP	0.47%	640.89K	23.08M	0	0
Sep 30, 2025	COMERICA BANK	0.48%	654.37K	23.57M	174.86K	+36.47%
Sep 30, 2025	BROWN ADVISORY INC	0.5%	676.99K	24.39M	105.05K	+18.37%
Sep 30, 2025	ABRDN PLC	0.53%	722.79K	26.04M	297.89K	+70.11%
Sep 30, 2025	MORGAN STANLEY	0.58%	784.48K	28.26M	-57.44K	-6.82%
Sep 30, 2025	SATURN V CAPITAL MANAGEMENT LLC	0.58%	788.44K	28.4M	244.22K	+44.88%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.95%	1.29M	46.59M	-124.3K	-8.77%
Sep 30, 2025	PIVOTAL BIOVENTURE PARTNERS INVESTMENT ADVISOR LLC	1.01%	1.37M	49.43M	67.3K	+5.16%
Sep 30, 2025	EVERSEPT PARTNERS, LP	1.05%	1.42M	51.22M	123.47K	+9.51%
Sep 30, 2025	JPMORGAN CHASE & CO	1.15%	1.57M	56.37M	366.27K	+30.55%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.12%	2.88M	103.9M	-127.1K	-4.22%
Sep 30, 2025	DEEP TRACK CAPITAL, LP	2.21%	3M	108.06M	850K	+39.53%
Sep 30, 2025	D. E. SHAW & CO., INC.	3.15%	4.29M	154.55M	1.2M	+38.93%
Sep 30, 2025	STATE STREET CORP	3.52%	4.79M	172.39M	-156.35K	-3.16%
Sep 30, 2025	BLACKROCK, INC.	7.32%	9.96M	358.61M	-686.27K	-6.45%
Sep 30, 2025	RA CAPITAL MANAGEMENT, L.P.	8.8%	11.97M	431.01M	0	0
Sep 30, 2025	VANGUARD GROUP INC	9.06%	12.32M	443.78M	323.37K	+2.70%
Sep 30, 2025	JANUS HENDERSON GROUP PLC	9.63%	13.1M	472.05M	-1.59M	-10.80%
Sep 30, 2025	STATE OF NEW JERSEY COMMON PENSION FUND D	0.05%	66.66K	2.4M	11.18K	+20.15%
Sep 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.05%	67.96K	2.45M	-1.81K	-2.60%
Sep 30, 2025	ENVESTNET ASSET MANAGEMENT INC	0.05%	69.81K	2.51M	-4.2K	-5.67%
Sep 30, 2025	Y-INTERCEPT (HONG KONG) LTD	0.05%	73.28K	2.64M	73.28K	+100.00%
Sep 30, 2025	BANQUE PICTET & CIE SA	0.06%	74.86K	2.7M	-8.51K	-10.20%
Sep 30, 2025	MACQUARIE GROUP LTD	0.06%	80K	2.88M	0	0
Sep 30, 2025	SCHRODER INVESTMENT MANAGEMENT GROUP	0.06%	80.24K	2.78M	1.11K	+1.41%
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.06%	80.48K	2.9M	-188.6K	-70.09%
Sep 30, 2025	NEO IVY CAPITAL MANAGEMENT	0.06%	83.11K	2.99M	58.87K	+242.85%
Sep 30, 2025	ACADIAN ASSET MANAGEMENT LLC	0.06%	84.38K	3.04M	84.38K	+100.00%
Sep 30, 2025	SEI INVESTMENTS CO	0.07%	89.95K	3.24M	50.24K	+126.52%
Sep 30, 2025	NAN FUNG TRINITY (HK) LTD	0.08%	104.25K	3.76M	0	0
Sep 30, 2025	AMERICAN CENTURY COMPANIES INC	0.25%	344.03K	12.39M	-7.03K	-2.00%
Sep 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.09%	121.79K	4.39M	-3.3K	-2.64%
Sep 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.09%	125K	4.5M	0	0
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0.09%	126.05K	4.54M	4.76K	+3.93%
Sep 30, 2025	LEGAL & GENERAL GROUP PLC	0.1%	130.4K	4.7M	-3.16K	-2.37%
Sep 30, 2025	HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND	0.1%	134.88K	4.86M	134.88K	+100.00%
Sep 30, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.11%	149.41K	5.38M	-15.41K	-9.35%
Sep 30, 2025	NOVO HOLDINGS A/S	0.67%	916.16K	33M	0	0
Sep 30, 2025	ROYAL BANK OF CANADA	0.7%	949.05K	34.18M	199.66K	+26.64%
Sep 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.24%	1.69M	60.82M	-1.48M	-46.74%
Sep 30, 2025	INVESCO LTD.	0.13%	179.08K	6.45M	17.45K	+10.79%
Sep 30, 2025	RHUMBLINE ADVISERS	0.13%	183.21K	6.6M	-15.28K	-7.70%
Sep 30, 2025	NORTHERN TRUST CORP	0.79%	1.07M	38.66M	-48.55K	-4.33%
Sep 30, 2025	SEGALL BRYANT & HAMILL, LLC	0.14%	184.8K	6.66M	4.56K	+2.53%
Sep 30, 2025	JUMP FINANCIAL, LLC	0.14%	191.7K	6.91M	-211.9K	-52.50%
Sep 30, 2025	C WORLDWIDE GROUP HOLDING A/S	0.14%	195K	7.02M	0	0
Sep 30, 2025	ASSENAGON ASSET MANAGEMENT S.A.	0.16%	219.95K	7.92M	171.97K	+358.46%
Sep 30, 2025	SWISS NATIONAL BANK	0.17%	225.1K	8.11M	3.8K	+1.72%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.19%	257.67K	9.28M	118.54K	+85.21%
Sep 30, 2025	CITIGROUP INC	0.23%	313.08K	11.28M	-116.21K	-27.07%
Sep 30, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.23%	314.34K	11.32M	26.54K	+9.22%
Sep 30, 2025	VICTORY CAPITAL MANAGEMENT INC	0.23%	314.89K	11.34M	-135.73K	-30.12%
Sep 30, 2025	KYNAM CAPITAL MANAGEMENT, LP	2.26%	3.07M	110.64M	0	0
Sep 30, 2025	WESTFIELD CAPITAL MANAGEMENT CO LP	2.74%	3.73M	134.45M	663.82K	+21.63%
Sep 30, 2025	PARADIGM BIOCAPITAL ADVISORS LP	2.78%	3.78M	136.33M	411.92K	+12.21%
Sep 30, 2025	FMR LLC	9.2%	12.51M	450.61M	358.88K	+2.95%
Sep 30, 2025	EVENTIDE ASSET MANAGEMENT, LLC	0.28%	379.33K	13.66M	-468.81K	-55.28%
Sep 30, 2025	BARCLAYS PLC	0.29%	393.91K	14.19M	-44.5K	-10.15%
Sep 30, 2025	DEUTSCHE BANK AG\	0.29%	397.79K	14.33M	134.83K	+51.28%
Sep 30, 2025	NUVEEN, LLC	0.36%	484.64K	17.46M	-3.13K	-0.64%
Sep 30, 2025	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.38%	519.73K	18.72M	-113.47K	-17.92%
Sep 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.51%	696.84K	25.1M	696.84K	+100.00%
Sep 30, 2025	MILLENNIUM MANAGEMENT LLC	0.7%	948.97K	34.18M	-155.87K	-14.11%
Sep 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.76%	1.03M	37.09M	-146.03K	-12.42%
Sep 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	3.7%	5.03M	181.28M	77.97K	+1.57%
Sep 30, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	6.11%	8.32M	299.52M	2.31M	+38.56%
Sep 30, 2025	MAVERICK CAPITAL LTD	0.95%	1.29M	46.45M	-21.04K	-1.61%
Sep 30, 2025	LOGOS GLOBAL MANAGEMENT LP	0.46%	625K	22.51M	625K	+100.00%
Sep 30, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.41%	553.85K	19.95M	-255.68K	-31.58%
Sep 30, 2025	JANE STREET GROUP, LLC	0.25%	343.7K	12.38B	45.95K	+15.43%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	0.72%	975.38K	35.13M	40.71K	+4.36%
Sep 30, 2025	JENNISON ASSOCIATES LLC	0.86%	1.17M	42.18M	-228.4K	-16.32%
Sep 30, 2025	UBS GROUP AG	0.62%	847.57K	30.53M	-533.28K	-38.62%
Jun 30, 2025	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.47%	633.2K	20.59M	633.2K	+100.00%
Jun 30, 2025	KYNAM CAPITAL MANAGEMENT, LP	2.26%	3.07M	99.86M	-128.41K	-4.01%
Jun 30, 2025	LAZARD ASSET MANAGEMENT LLC	0.38%	512.14K	16.65M	-45.66K	-8.19%
Jun 30, 2025	CITIGROUP INC	0.32%	429.28K	13.96M	-191.8K	-30.88%
Jun 30, 2025	FMR LLC	8.93%	12.15M	395.03M	-361.18K	-2.89%
Jun 30, 2025	RA CAPITAL MANAGEMENT, L.P.	8.8%	11.97M	389.01M	-223.16K	-1.83%
Jun 30, 2025	ROYAL BANK OF CANADA	0.55%	749.39K	24.36M	719.92K	+2,442.81%
Jun 30, 2025	CLEARBRIDGE INVESTMENTS, LLC	0.47%	646.06K	21M	-574.4K	-47.06%
Jun 30, 2025	BAKER BROS. ADVISORS LP	0.47%	640.89K	20.84M	0	0
Jun 30, 2025	RAYMOND JAMES FINANCIAL INC	0.22%	299.58K	9.74M	6.45K	+2.20%
Jun 30, 2025	SIREN, L.L.C.	0.22%	295.54K	9.61M	0	0
Jun 30, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.21%	287.8K	9.36M	287.8K	+100.00%
Jun 30, 2025	ALYESKA INVESTMENT GROUP, L.P.	0.18%	244.78K	7.96M	80.14K	+48.67%
Jun 30, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	0.17%	225K	7.31M	0	0
Jun 30, 2025	AQUATIC CAPITAL MANAGEMENT LLC	0.15%	206.17K	6.7M	206.17K	+100.00%
Jun 30, 2025	WOODLINE PARTNERS LP	0.15%	200.08K	6.5M	-911.7K	-82.00%
Jun 30, 2025		0.36%	487.77K	15.86M	-68.06K	-12.25%
Jun 30, 2025	C WORLDWIDE GROUP HOLDING A/S	0.14%	195K	6.34M	100K	+105.26%
Jun 30, 2025	EVENTIDE ASSET MANAGEMENT, LLC	0.62%	848.14K	27.57M	377.91K	+80.37%
Jun 30, 2025	POLAR CAPITAL HOLDINGS PLC	0.61%	825.8K	26.85M	-256.68K	-23.71%
Jun 30, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.6%	809.53K	26.32M	809.53K	+100.00%
Jun 30, 2025	TWINBEECH CAPITAL LP	0.37%	503.25K	16.36M	98.28K	+24.27%
Jun 30, 2025	COMERICA BANK	0.35%	479.51K	15.59M	119.32K	+33.13%
Jun 30, 2025	VICTORY CAPITAL MANAGEMENT INC	0.33%	450.62K	14.65M	229.8K	+104.07%
Jun 30, 2025	BANK OF NEW YORK MELLON CORP	0.33%	449.69K	14.62M	31.68K	+7.58%
Jun 30, 2025	BROWN ADVISORY INC	0.42%	571.94K	18.59M	1.68K	+0.29%
Jun 30, 2025	D. E. SHAW & CO., INC.	2.27%	3.09M	100.41B	2.22M	+255.86%
Jun 30, 2025	ABRDN PLC	0.31%	424.91K	13.81M	160.17K	+60.50%
Jun 30, 2025	JUMP FINANCIAL, LLC	0.3%	403.6K	13.12M	303.5K	+303.19%
Jun 30, 2025	WALLEYE CAPITAL LLC	0.27%	362.61K	11.79M	256.64K	+242.19%
Jun 30, 2025	FIERA CAPITAL CORP	0.26%	353.84K	11.5M	-5.36K	-1.49%
Jun 30, 2025	AMERICAN CENTURY COMPANIES INC	0.26%	351.05K	11.41M	-236K	-40.20%
Jun 30, 2025	IKARIAN CAPITAL, LLC	0.22%	305K	9.92M	105K	+52.50%
Jun 30, 2025	TANG CAPITAL MANAGEMENT LLC	0.22%	300K	9.75M	0	0
Jun 30, 2025	SEGALL BRYANT & HAMILL, LLC	0.13%	180.24K	5.86M	30.48K	+20.35%
Jun 30, 2025	CORMORANT ASSET MANAGEMENT, LP	0.13%	175K	5.69M	0	0
Jun 30, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.41%	555.01K	18.04M	41.01K	+7.98%
Jun 30, 2025	BARCLAYS PLC	0.32%	438.41K	14.25M	212.29K	+93.88%
Jun 30, 2025	BLACKROCK, INC.	7.82%	10.64M	345.98M	62.77K	+0.59%
Jun 30, 2025	DEEP TRACK CAPITAL, LP	1.58%	2.15M	69.9M	1.4M	+186.67%
Jun 30, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	4.41%	6M	195.1M	3.3M	+122.04%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	1.04%	1.42M	46.09M	84.33K	+6.32%
Jun 30, 2025	JENNISON ASSOCIATES LLC	1.03%	1.4M	45.49M	273.58K	+24.30%
Jun 30, 2025	NORTHERN TRUST CORP	0.82%	1.12M	36.47M	-1.06K	-0.09%
Jun 30, 2025	MILLENNIUM MANAGEMENT LLC	0.81%	1.1M	35.92M	691.41K	+167.24%
Jun 30, 2025	FRANKLIN RESOURCES INC	0.69%	939.28K	30.54M	-2.15M	-69.59%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0.8%	1.08M	35.2M	291.86K	+36.91%
Jun 30, 2025	WESTFIELD CAPITAL MANAGEMENT CO LP	2.26%	3.07M	99.77M	913.76K	+42.40%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.21%	3.01M	97.9M	142.09K	+4.95%
Jun 30, 2025	MAVERICK CAPITAL LTD	0.96%	1.31M	42.61M	102.51K	+8.49%
Jun 30, 2025	PIVOTAL BIOVENTURE PARTNERS INVESTMENT ADVISOR LLC	0.96%	1.31M	42.43M	594.39K	+83.63%
Jun 30, 2025	EVERSEPT PARTNERS, LP	0.95%	1.3M	42.21M	741.44K	+133.10%
Jun 30, 2025	JPMORGAN CHASE & CO	0.88%	1.2M	38.97M	-701.41K	-36.91%
Jun 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.86%	1.18M	38.23M	124.98K	+11.90%
Jun 30, 2025	NORGES BANK	0.73%	987.67K	32.11M	987.67K	+100.00%
Jun 30, 2025	NOVO HOLDINGS A/S	0.67%	916.16K	29.78M	1.16K	+0.13%
Jun 30, 2025	SATURN V CAPITAL MANAGEMENT LLC	0.4%	544.22K	17.69M	311.93K	+134.28%
Jun 30, 2025	TD ASSET MANAGEMENT INC	0.4%	539.78K	17.55M	236.19K	+77.80%
Jun 30, 2025	ENSIGN PEAK ADVISORS, INC	0.39%	532.2K	17.3M	-211.96K	-28.48%
Jun 30, 2025	JANUS HENDERSON GROUP PLC	10.8%	14.69M	477.66M	2.93M	+24.87%
Jun 30, 2025	UBS GROUP AG	1.02%	1.38M	44.89M	300.46K	+27.81%
Jun 30, 2025	CITADEL ADVISORS LLC	0.8%	1.09M	35.46B	994.35K	+1,031.62%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.69%	934.67K	30.39B	-212.63K	-18.53%
Jun 30, 2025	MORGAN STANLEY	0.62%	841.92K	27.37B	234.97K	+38.71%
Jun 30, 2025	NUVEEN, LLC	0.36%	487.77K	15.86M	-68.06K	-12.25%
Jun 30, 2025	VANGUARD GROUP INC	8.82%	12M	390.03M	-46.72K	-0.39%
Jun 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	3.64%	4.95M	161.08M	-1.46M	-22.79%
Jun 30, 2025	STATE STREET CORP	3.63%	4.94M	160.67M	534.55K	+12.13%
Jun 30, 2025	CAPITAL RESEARCH GLOBAL INVESTORS	3.51%	4.77M	155.13M	-1.34M	-21.90%
Jun 30, 2025	PARADIGM BIOCAPITAL ADVISORS LP	2.48%	3.37M	109.65M	1.68M	+98.81%
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	2.33%	3.17M	103.07M	-371.76K	-10.50%
Jun 30, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	0.35%	474.41K	15.42M	-65K	-12.05%
Mar 31, 2025	UBS GROUP AG	0.8%	1.08M	40.8M	343.84K	+46.68%
Mar 31, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	0.78%	1.06M	40.06M	-105.97K	-9.08%
Mar 31, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.77%	1.05M	42.17M	32.83K	+3.23%
Mar 31, 2025		0.41%	555.83K	20.99M	555.83K	+100.00%
Mar 31, 2025	EVERSEPT PARTNERS, LP	0.41%	557.07K	21.03M	429.48K	+336.62%
Mar 31, 2025	BROWN ADVISORY INC	0.42%	570.26K	21.53M	14.05K	+2.53%
Mar 31, 2025	CLEARBRIDGE INVESTMENTS, LLC	0.9%	1.22M	46.08M	117.97K	+10.70%
Mar 31, 2025	INVESCO LTD.	0.93%	1.26M	47.42M	89.77K	+7.70%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.98%	1.33M	50.35M	-8.39K	-0.63%
Mar 31, 2025	ALLIANCEBERNSTEIN L.P.	1.26%	1.7M	64.35M	-75.15K	-4.22%
Mar 31, 2025	JPMORGAN CHASE & CO	1.4%	1.9M	71.75M	164.52K	+9.48%
Mar 31, 2025	CITIGROUP INC	0.46%	621.08K	23.45M	241.87K	+63.78%
Mar 31, 2025	BAKER BROS. ADVISORS LP	0.47%	640.89K	24.2M	592K	+1,211.01%
Mar 31, 2025	AMERIPRISE FINANCIAL INC	0.5%	678.58K	25.61M	-38.19K	-5.33%
Mar 31, 2025	PERCEPTIVE ADVISORS LLC	0.52%	706.57K	26.68M	-1.01M	-58.88%
Mar 31, 2025	PIVOTAL BIOVENTURE PARTNERS INVESTMENT ADVISOR LLC	0.52%	710.73K	26.84M	6.9K	+0.98%
Mar 31, 2025	DEEP TRACK CAPITAL, LP	0.55%	750K	28.32M	750K	+100.00%
Mar 31, 2025	HOOD RIVER CAPITAL MANAGEMENT LLC	0.55%	751.61K	28.38M	350.17K	+87.23%
Mar 31, 2025	D. E. SHAW & CO., INC.	0.64%	867.89K	32.77M	92.24K	+11.89%
Mar 31, 2025	POLAR CAPITAL HOLDINGS PLC	0.8%	1.08M	40.87M	108.83K	+11.18%
Mar 31, 2025	WOODLINE PARTNERS LP	0.82%	1.11M	41.98M	-9.15K	-0.82%
Mar 31, 2025	NORTHERN TRUST CORP	0.83%	1.12M	42.4M	-37.05K	-3.19%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.85%	1.15M	43.32M	-1.98M	-63.34%
Mar 31, 2025	DEUTSCHE BANK AG\	0.88%	1.2M	45.22M	-15.02K	-1.24%
Mar 31, 2025	PARADIGM BIOCAPITAL ADVISORS LP	1.25%	1.7M	64.06M	273.69K	+19.24%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.11%	2.87M	108.36M	66.17K	+2.36%
Mar 31, 2025	WESTFIELD CAPITAL MANAGEMENT CO LP	1.59%	2.16M	81.38M	-411.62K	-16.04%
Mar 31, 2025	KYNAM CAPITAL MANAGEMENT, LP	2.36%	3.2M	120.83M	863.2K	+36.94%
Mar 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	2.61%	3.54M	133.75M	-424.95K	-10.71%
Mar 31, 2025	CAPITAL RESEARCH GLOBAL INVESTORS	4.5%	6.11M	230.72M	-100.42K	-1.62%
Mar 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	4.73%	6.42M	242.3M	1.97M	+44.40%
Mar 31, 2025	AVORO CAPITAL ADVISORS LLC	0.74%	1M	37.76M	-175K	-14.89%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0.58%	790.81K	29.86M	320.9K	+68.29%
Mar 31, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	1.99%	2.7M	102.05M	-158.03K	-5.52%
Mar 31, 2025	BLACKROCK, INC.	7.8%	10.58M	399.48M	-526.59K	-4.74%
Mar 31, 2025	JANUS HENDERSON GROUP PLC	8.67%	11.77M	815.87M	1.19M	+11.25%
Mar 31, 2025	VANGUARD GROUP INC	8.88%	12.04M	454.77M	82.12K	+0.69%
Mar 31, 2025	STATE STREET CORP	3.25%	4.41M	166.43M	-131.72K	-2.90%
Mar 31, 2025	RA CAPITAL MANAGEMENT, L.P.	8.98%	12.19M	460.26M	3.5M	+40.28%
Mar 31, 2025	COMMODORE CAPITAL LP	1.22%	1.65M	62.3M	25K	+1.54%
Mar 31, 2025	FRANKLIN RESOURCES INC	2.28%	3.09M	116.64M	219.7K	+7.66%
Mar 31, 2025	AMERICAN CENTURY COMPANIES INC	0.43%	587.05K	22.17M	-18.21K	-3.01%
Mar 31, 2025	ENSIGN PEAK ADVISORS, INC	0.55%	744.16K	28.1M	158.03K	+26.96%
Mar 31, 2025	JENNISON ASSOCIATES LLC	0.83%	1.13M	42.51M	-120.83K	-9.69%
Mar 31, 2025	MAVERICK CAPITAL LTD	0.89%	1.21M	45.62M	6.2K	+0.52%
Mar 31, 2025	FMR LLC	9.22%	12.51M	472.46M	-579.41K	-4.43%
Mar 31, 2025	LAZARD ASSET MANAGEMENT LLC	0.41%	557.79K	21.06M	71.03K	+14.59%
Mar 31, 2025	NOVO HOLDINGS A/S	0.67%	915K	34.55M	165K	+22.00%
Mar 31, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	0.4%	539.41K	20.37M	0	0
Mar 31, 2025	MORGAN STANLEY	0.45%	606.95K	22.92M	-86.38K	-12.46%
Mar 31, 2024	BLACKROCK INC.	9.79%	9.51M	649.83M	937.16K	+10.93%
Mar 31, 2024	AMUNDI	0.31%	302.36K	18.33M	-27.43K	-8.32%
Mar 31, 2024	SAMLYN CAPITAL, LLC	0.31%	302.68K	20.68M	-26.53K	-8.06%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.32%	311.35K	21.27M	30.5K	+10.86%
Mar 31, 2024	EAGLE ASSET MANAGEMENT INC	0.35%	338.8K	22.61M	-15.32K	-4.33%
Mar 31, 2024	MAVERICK CAPITAL LTD	0.37%	355.13K	24.26M	355.13K	+100.00%
Mar 31, 2024	D. E. SHAW & CO., INC.	0.38%	367.25K	25.09M	-71.06K	-16.21%
Mar 31, 2024	FARALLON CAPITAL MANAGEMENT LLC	0.39%	377.4K	25.78M	374K	+11,000.00%
Mar 31, 2024	ENSIGN PEAK ADVISORS, INC	0.49%	475.7K	32.5M	114.57K	+31.73%
Mar 31, 2024	MORGAN STANLEY	0.5%	490.45K	33.5M	-46.91K	-8.73%
Mar 31, 2024	AVORO CAPITAL ADVISORS LLC	0.59%	575K	39.28M	575K	+100.00%
Mar 31, 2024	EVENTIDE ASSET MANAGEMENT, LLC	0.68%	657.21K	44.89M	50K	+8.23%
Mar 31, 2024	CORMORANT ASSET MANAGEMENT, LP	0.71%	685K	46.79M	20K	+3.01%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.72%	698.49K	47.71M	217.37K	+45.18%
Mar 31, 2024	KYNAM CAPITAL MANAGEMENT, LP	0.77%	745K	50.89M	-257.41K	-25.68%
Mar 31, 2024	PIVOTAL BIOVENTURE PARTNERS INVESTMENT ADVISOR LLC	0.82%	793.04K	54.17M	0	0
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.86%	833.62K	56.94M	103.18K	+14.13%
Mar 31, 2024	NOVO HOLDINGS A/S	0.87%	845K	57.72M	0	0
Mar 31, 2024	COMMODORE CAPITAL LP	0.89%	860K	58.75M	-240K	-21.82%
Mar 31, 2024	PICTET ASSET MANAGEMENT HOLDING SA	0.89%	861.57K	58.85M	-287.64K	-25.03%
Mar 31, 2024	NORTHERN TRUST CORP	1%	968.76K	66.18M	84.49K	+9.55%
Mar 31, 2024	ORBIMED ADVISORS LLC	1.1%	1.07M	72.83M	-86.96K	-7.54%
Mar 31, 2024	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	1.17%	1.14M	77.83M	-25K	-2.15%
Mar 31, 2024	JPMORGAN CHASE & CO	1.2%	1.16M	79.36M	756.44K	+186.62%
Mar 31, 2024	BRAIDWELL LP	1.25%	1.21M	82.84M	-77.26K	-5.99%
Mar 31, 2024	INVESCO LTD.	1.27%	1.23M	84.33M	1.01M	+443.95%
Mar 31, 2024	FMR LLC	16.74%	16.26M	1.11B	2.05M	+14.41%
Mar 31, 2024	PARADIGM BIOCAPITAL ADVISORS LP	1.28%	1.24M	84.7M	1.24M	+100.00%
Mar 31, 2024	JENNISON ASSOCIATES LLC	1.29%	1.26M	85.86M	-219.27K	-14.85%
Mar 31, 2024	FRED ALGER MANAGEMENT, LLC	1.44%	1.4M	95.41M	-273.48K	-16.37%
Mar 31, 2024	WESTFIELD CAPITAL MANAGEMENT CO LP	1.63%	1.59M	108.35M	130.5K	+8.97%
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	1.83%	1.78M	121.64M	-134.34K	-7.02%
Mar 31, 2024	DRIEHAUS CAPITAL MANAGEMENT LLC	1.92%	1.87M	127.59M	193.44K	+11.55%
Mar 31, 2024	PERCEPTIVE ADVISORS LLC	1.99%	1.93M	132.03M	844.27K	+77.56%
Mar 31, 2024	FRANKLIN RESOURCES INC	2.21%	2.15M	146.71M	1.07M	+99.43%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	2.35%	2.29M	156.27M	313.87K	+15.90%
Mar 31, 2024	DARWIN GLOBAL MANAGEMENT, LTD.	2.83%	2.75M	187.91M	2.17M	+374.31%
Mar 31, 2024	CAPITAL RESEARCH GLOBAL INVESTORS	4.26%	4.14M	282.84M	700.41K	+20.36%
Mar 31, 2024	WELLINGTON MANAGEMENT GROUP LLP	5.06%	4.92M	336.04M	487.45K	+11.00%
Mar 31, 2024	RA CAPITAL MANAGEMENT, L.P.	8.44%	8.2M	560.4M	312.5K	+3.96%
Mar 31, 2024	VANGUARD GROUP INC	10.02%	9.74M	665.15M	1.28M	+15.20%
Mar 31, 2024	LORD, ABBETT & CO. LLC	0.4%	384.36K	26.26M	-1.21K	-0.31%
Mar 31, 2024	WOODLINE PARTNERS LP	0.41%	393.7K	26.89M	353	+0.09%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.42%	412.53K	28.18M	13.41K	+3.36%
Mar 31, 2024	FEDERATED HERMES, INC.	0.44%	425.75K	29.08M	31.56K	+8.01%
Mar 31, 2024	AMERICAN CENTURY COMPANIES INC	0.48%	461.72K	31.54M	54.5K	+13.38%
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	3.27%	3.18M	216.97M	498.36K	+18.61%
Mar 31, 2024	STATE STREET CORP	3.43%	3.34M	227.96M	-52.44K	-1.55%
Mar 31, 2024	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	3.66%	3.55M	242.7M	2.31M	+185.14%
Mar 31, 2024	STATE OF WISCONSIN INVESTMENT BOARD	0.06%	60.68K	4.14M	3.49K	+6.09%
Mar 31, 2024	BANQUE PICTET & CIE SA	0.06%	60.89K	4.16M	60.89K	+100.00%
Mar 31, 2024	FIRST TRUST ADVISORS LP	0.07%	63.83K	4.36M	-13.81K	-17.79%
Mar 31, 2024	RAYMOND JAMES & ASSOCIATES	0.07%	66.33K	4.53M	14.78K	+28.67%
Mar 31, 2024	ALPS ADVISORS INC	0.08%	76.32K	5.21M	11.02K	+16.88%
Mar 31, 2024	AFFINITY ASSET ADVISORS, LLC	0.08%	80K	5.46M	55K	+220.00%
Mar 31, 2024	NICHOLAS INVESTMENT PARTNERS, LP	0.09%	85.64K	5.85M	-25.08K	-22.65%
Mar 31, 2024	LEGAL & GENERAL GROUP PLC	0.1%	94.78K	6.47B	14.78K	+18.47%
Mar 31, 2024	MONASHEE INVESTMENT MANAGEMENT LLC	0.1%	100K	6.83M	62.5K	+166.67%
Mar 31, 2024	NEUBERGER BERMAN GROUP LLC	0.11%	102.31K	6.99M	16.14K	+18.74%
Mar 31, 2024	SEI INVESTMENTS CO	0.11%	103.4K	7.06B	55	+0.05%
Mar 31, 2024	CAPSTONE INVESTMENT ADVISORS, LLC	0.11%	109.39K	7.47M	109.39K	+100.00%
Mar 31, 2024	MOODY ALDRICH PARTNERS LLC	0.12%	118.6K	8.1M	-29.33K	-19.82%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.12%	119.08K	8.13M	14.01K	+13.33%
Mar 31, 2024	CREDIT SUISSE AG/	0.13%	123.97K	8.47M	26.17K	+26.75%
Mar 31, 2024	RAFFERTY ASSET MANAGEMENT, LLC	0.13%	126.16K	8.62M	-32.25K	-20.36%
Mar 31, 2024	PIER CAPITAL, LLC	0.13%	127.38K	8.7M	-74.18K	-36.80%
Mar 31, 2024	CITIGROUP INC	0.15%	144.87K	9.9M	65.96K	+83.58%
Mar 31, 2024	RHUMBLINE ADVISERS	0.15%	148.29K	10.13M	17.74K	+13.59%
Mar 31, 2024	CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM	0.16%	156.99K	10.72M	58.85K	+59.97%
Mar 31, 2024	UBS GROUP AG	0.18%	176.08K	12.03M	10.04K	+6.05%
Mar 31, 2024	SWISS NATIONAL BANK	0.18%	178K	12.16M	30.1K	+20.35%
Mar 31, 2024	ABRDN PLC	0.2%	194.23K	13.27M	0	0
Mar 31, 2024	FIRST TURN MANAGEMENT, LLC	0.27%	260.28K	17.78M	-97.25K	-27.20%
Mar 31, 2024	CERCANO MANAGEMENT LLC	0.28%	272.15K	18.59M	272.15K	+100.00%
Mar 31, 2024	VICTORY CAPITAL MANAGEMENT INC	0.29%	280.88K	19.19M	-98.53K	-25.97%
Mar 31, 2024	TD ASSET MANAGEMENT INC	0.29%	281.29K	19.21B	114.25K	+68.40%
Mar 31, 2024	JANUS HENDERSON GROUP PLC	7.9%	7.67M	524.12M	692.49K	+9.92%
Dec 31, 2023	DRIEHAUS CAPITAL MANAGEMENT LLC	1.65%	1.67M	105.15M	350.48K	+26.47%
Dec 31, 2023	ALLIANCEBERNSTEIN L.P.	1.88%	1.92M	120.26M	-28.78K	-1.48%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.94%	1.97M	123.95M	98.39K	+5.25%
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	2.63%	2.68M	168.17M	260.17K	+10.76%
Dec 31, 2023	STATE STREET CORP	3.33%	3.39M	212.86M	244.27K	+7.77%
Dec 31, 2023	CAPITAL RESEARCH GLOBAL INVESTORS	3.38%	3.44M	216.04M	75.98K	+2.26%
Dec 31, 2023	WELLINGTON MANAGEMENT GROUP LLP	4.36%	4.43M	278.32M	4.43M	+100.00%
Dec 31, 2023	JANUS HENDERSON GROUP PLC	6.87%	6.98M	438.41M	-79.21K	-1.12%
Dec 31, 2023	RA CAPITAL MANAGEMENT, L.P.	7.76%	7.89M	495.57M	0	0
Dec 31, 2023	VANGUARD GROUP INC	8.31%	8.45M	530.81M	168.13K	+2.03%
Dec 31, 2023	BLACKROCK INC.	8.44%	8.58M	538.56M	1.15M	+15.56%
Dec 31, 2023	FMR LLC	13.98%	14.21M	892.6M	136.33K	+0.97%
Dec 31, 2023	EAGLE ASSET MANAGEMENT INC	0.35%	354.12K	22.24M	-885	-0.25%
Dec 31, 2023	GREAT POINT PARTNERS LLC	0.35%	360K	22.61M	-171.21K	-32.23%
Dec 31, 2023	ENSIGN PEAK ADVISORS, INC	0.36%	361.13K	22.68M	85.35K	+30.95%
Dec 31, 2023		0.35%	357.53K	22.45M	357.53K	+100.00%
Dec 31, 2023	VICTORY CAPITAL MANAGEMENT INC	0.37%	379.41K	23.83M	-51.54K	-11.96%
Dec 31, 2023	LORD, ABBETT & CO. LLC	0.38%	385.57K	24.21M	385.57K	+100.00%
Dec 31, 2023	WOODLINE PARTNERS LP	0.39%	393.35K	24.7M	12.74K	+3.35%
Dec 31, 2023	FEDERATED HERMES, INC.	0.39%	394.19K	24.76M	-1.62K	-0.41%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.39%	399.12K	25.06M	3.09K	+0.78%
Dec 31, 2023	PERCEPTIVE ADVISORS LLC	1.07%	1.09M	68.36M	-254.27K	-18.94%
Dec 31, 2023	COMMODORE CAPITAL LP	1.08%	1.1M	69.08M	0	0
Dec 31, 2023	ORBIMED ADVISORS LLC	1.13%	1.15M	72.41M	145.94K	+14.49%
Dec 31, 2023	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	1.15%	1.16M	73.12M	0	0
Dec 31, 2023	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	1.23%	1.25M	78.25M	41.41K	+3.44%
Dec 31, 2023	BRAIDWELL LP	1.27%	1.29M	81.01M	-329.59K	-20.35%
Dec 31, 2023	WESTFIELD CAPITAL MANAGEMENT CO LP	1.43%	1.46M	91.41M	451.68K	+44.99%
Dec 31, 2023	FRANKLIN RESOURCES INC	1.06%	1.08M	67.63M	120.99K	+12.66%
Dec 31, 2023	KYNAM CAPITAL MANAGEMENT, LP	0.99%	1M	62.95M	-300K	-23.03%
Dec 31, 2023	NORGES BANK	0.9%	915.51K	57.49M	915.51K	+100.00%
Dec 31, 2023	NORTHERN TRUST CORP	0.87%	884.27K	55.53M	-12.37K	-1.38%
Dec 31, 2023	NOVO HOLDINGS A/S	0.83%	845K	53.07M	0	0
Dec 31, 2023	PIVOTAL BIOVENTURE PARTNERS INVESTMENT ADVISOR LLC	0.78%	793.04K	49.8M	0	0
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.72%	730.44K	45.87M	17.57K	+2.46%
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	0.68%	691.43K	43.42M	108.56K	+18.63%
Dec 31, 2023	CORMORANT ASSET MANAGEMENT, LP	0.65%	665K	41.76M	0	0
Dec 31, 2023	EVENTIDE ASSET MANAGEMENT, LLC	0.6%	607.21K	38.13M	214.21K	+54.51%
Dec 31, 2023	DARWIN GLOBAL MANAGEMENT, LTD.	0.57%	579.96K	36.42M	579.96K	+100.00%
Dec 31, 2023	AVIDITY PARTNERS MANAGEMENT LP	0.56%	570.14K	35.8M	-186.03K	-24.60%
Dec 31, 2023	MORGAN STANLEY	0.53%	537.37K	33.75M	127.82K	+31.21%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.47%	481.12K	30.21M	52.01K	+12.12%
Dec 31, 2023	D. E. SHAW & CO., INC.	0.43%	438.31K	27.53M	-100.07K	-18.59%
Dec 31, 2023	SOLEUS CAPITAL MANAGEMENT, L.P.	0.41%	415.45K	26.09M	-84.2K	-16.85%
Dec 31, 2023	AMERICAN CENTURY COMPANIES INC	0.4%	407.23K	25.57M	35.49K	+9.55%
Dec 31, 2023	JPMORGAN CHASE & CO	0.4%	405.33K	25.45M	-232.39K	-36.44%
Dec 31, 2023	JENNISON ASSOCIATES LLC	1.45%	1.48M	92.7M	-278.54K	-15.87%
Dec 31, 2023	FRED ALGER MANAGEMENT, LLC	1.64%	1.67M	104.89M	-423.12K	-20.21%

Insiders

Among the PCVX insiders holding of 0.66% of the stake in company, WASSIL JIM, CHIEF OPERATING OFFICER, holds the largest shares of 160.74K. PICKERING GRANT, CHIEF EXECUTIVE OFFICER, is the second largest PCVX insider with ownership of 136.22K shares. GUGGENHIME ANDREW, PRESIDENT AND CFO, stands third with possession of 109.49K shares of that stake.

Insiders	Designation	Shares Held
WASSIL JIM	CHIEF OPERATING OFFICER	160.74K
PICKERING GRANT	CHIEF EXECUTIVE OFFICER	136.22K
GUGGENHIME ANDREW	PRESIDENT AND CFO	109.49K
EYDELMAN MIKHAIL	SVP, GEN COUNSEL & CORP SEC	41.62K
COWAN ELVIA	SVP, Finance & CAO	28.98K
DHALIWAL HARPREET S.	Chief Technical Ops Officer	23.93K
LOXAM TERI	director	7.18K
LUKATCH HEATH	director	5.63K
GILBERT HALLEY E	director	5.63K

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
May 01, 2026	WASSIL JIM	SALE	56.83	2.25K	127.87K	160.74K
Apr 07, 2026	COWAN ELVIA	SALE	60.00	3K	180K	28.98K
Apr 01, 2026	WASSIL JIM	SALE	58.93	838	49.39K	162.99K
Mar 17, 2026	COWAN ELVIA	SALE	56.26	405	22.79K	28.98K
Mar 11, 2026	COWAN ELVIA	SALE	58.59	2.5K	146.48K	30.87K
Mar 10, 2026	WASSIL JIM	SALE	59.16	4.97K	293.91K	166.82K
Dec 31, 2025	DHALIWAL HARPREET S.	SALE	46.69	9.74K	454.89K	23.93K
Dec 23, 2025	COWAN ELVIA	SALE	47.94	6.72K	321.93K	14.53K
Mar 05, 2025	EYDELMAN MIKHAIL	SALE	72.37	112	8.11K	41.62K
Mar 03, 2025	WASSIL JIM	SALE	73.84	2.09K	153.95K	154.93K
Feb 18, 2025	GUGGENHIME ANDREW	SALE	84.58	1.82K	153.77K	109.49K
Feb 05, 2025	EYDELMAN MIKHAIL	SALE	91.71	255	23.39K	28.22K
Feb 03, 2025	WASSIL JIM	SALE	87.94	20	1.76K	205.7K
Jan 21, 2025	GUGGENHIME ANDREW	SALE	87.70	683	59.9K	109.49K
Jan 15, 2025	LOXAM TERI	SALE	88.54	529	46.84K	7.18K
Jan 06, 2025	EYDELMAN MIKHAIL	SALE	86.52	125	10.82K	28.22K
Jan 02, 2025	WASSIL JIM	SALE	84.43	1.16K	98.02K	205.7K
Dec 18, 2024	GUGGENHIME ANDREW	SALE	90.24	280	25.27K	109.49K
Dec 09, 2024	PICKERING GRANT	SALE	93.10	222	20.67K	136.22K
Dec 05, 2024	EYDELMAN MIKHAIL	SALE	92.90	388	36.05K	28.7K
Dec 02, 2024	PICKERING GRANT	SALE	94.06	2.24K	210.88K	450.3K
Dec 02, 2024	WASSIL JIM	SALE	94.06	1.13K	106.01K	205.7K
Nov 18, 2024	GUGGENHIME ANDREW	SALE	87.05	132	11.49K	109.49K
Nov 05, 2024	EYDELMAN MIKHAIL	SALE	107.50	1.27K	136.84K	28.62K
Nov 01, 2024	PICKERING GRANT	SALE	108.50	1.73K	188.03K	435.22K
Nov 01, 2024	WASSIL JIM	SALE	108.93	240	26.14K	205.7K
Oct 18, 2024	GUGGENHIME ANDREW	SALE	116.19	5.89K	683.9K	90.38K
Oct 07, 2024	EYDELMAN MIKHAIL	SALE	111.68	67	7.48K	28.62K
Oct 07, 2024	PICKERING GRANT	SALE	110.20	537	59.18K	138.58K
Oct 01, 2024	WASSIL JIM	SALE	114.95	2.34K	268.86K	200.65K
Oct 01, 2024	EYDELMAN MIKHAIL	SALE	115.01	1.03K	118.46K	28.62K
Oct 01, 2024	PICKERING GRANT	SALE	114.98	5.47K	629.41K	450.22K
Sep 18, 2024	GUGGENHIME ANDREW	SALE	117.53	829	97.43K	90.38K
Sep 17, 2024	LOXAM TERI	SALE	117.51	256	30.08K	7.18K
Sep 16, 2024	WASSIL JIM	SALE	116.96	222	25.97K	200.65K
Sep 03, 2024	EYDELMAN MIKHAIL	SALE	117.28	80	9.38K	30.83K
Sep 03, 2024	COWAN ELVIA	SALE	107.67	5K	538.35K	12.72K
Sep 03, 2024	WASSIL JIM	SALE	117.03	10	1.17K	207.5K
Aug 23, 2024	PICKERING GRANT	SALE	79.25	8.31K	658.91K	478.89K
Aug 19, 2024	GUGGENHIME ANDREW	SALE	79.14	3.01K	237.88K	96.72K
Aug 01, 2024	EYDELMAN MIKHAIL	SALE	79.29	185	14.67K	30.83K
Aug 01, 2024	WASSIL JIM	SALE	79.47	23	1.83K	207.5K
Aug 01, 2024	PICKERING GRANT	SALE	78.78	1.31K	103.05K	142.13K
Jul 23, 2024	PICKERING GRANT	SALE	84.53	9.28K	784.59K	478.89K
Jul 18, 2024	GUGGENHIME ANDREW	SALE	83.14	926	76.98K	96.72K
Jul 16, 2024	COWAN ELVIA	SALE	85.00	5K	425K	12.72K
Jul 08, 2024	COWAN ELVIA	SALE	80.00	5K	400K	12.72K
Jul 01, 2024	PICKERING GRANT	SALE	76.89	557	42.83K	143.44K
Jul 01, 2024	EYDELMAN MIKHAIL	SALE	76.90	754	57.98K	30.83K
Jul 01, 2024	WASSIL JIM	SALE	77.22	111	8.57K	210.5K
Jun 24, 2024	PICKERING GRANT	SALE	76.80	188	14.44K	478.89K
Jun 18, 2024	GUGGENHIME ANDREW	SALE	72.56	348	25.25K	96.72K
Jun 03, 2024	EYDELMAN MIKHAIL	SALE	73.64	260	19.15K	31.16K
Jun 03, 2024	PICKERING GRANT	SALE	73.46	117	8.59K	144.75K
Jun 03, 2024	GILBERT HALLEY E	SALE	73.00	18.2K	1.33M	5.63K
Jun 03, 2024	WASSIL JIM	SALE	73.47	460	33.8K	213.5K
May 23, 2024	PICKERING GRANT	SALE	69.84	8.79K	613.82K	477.85K
May 20, 2024	GUGGENHIME ANDREW	SALE	75.46	4.46K	336.25K	95.68K
May 01, 2024	EYDELMAN MIKHAIL	SALE	63.90	144	9.2K	30.6K
May 01, 2024	WASSIL JIM	SALE	63.65	185	11.77K	215.46K
May 01, 2024	PICKERING GRANT	SALE	63.84	46	2.94K	146.05K
Apr 23, 2024	PICKERING GRANT	SALE	61.92	15K	928.85K	477.85K
Apr 18, 2024	GUGGENHIME ANDREW	SALE	61.90	376	23.28K	95.68K
Apr 01, 2024	WASSIL JIM	SALE	67.23	677	45.51K	218.29K
Apr 01, 2024	EYDELMAN MIKHAIL	SALE	67.42	270	18.2K	30.6K
Apr 01, 2024	PICKERING GRANT	SALE	68.10	3	204.3	147.36K
Mar 25, 2024	PICKERING GRANT	SALE	67.50	1.55K	104.62K	477.85K
Mar 18, 2024	GUGGENHIME ANDREW	SALE	69.64	236	16.44K	95.68K
Mar 01, 2024	PICKERING GRANT	SALE	74.69	363	27.11K	148.67K
Mar 01, 2024	COWAN ELVIA	SALE	74.90	4.9K	367.08K	12.48K
Mar 01, 2024	EYDELMAN MIKHAIL	SALE	74.77	445	33.27K	31.21K
Mar 01, 2024	WASSIL JIM	SALE	74.69	763	56.99K	220.85K
Feb 26, 2024	PICKERING GRANT	SALE	79.03	30K	2.37M	375.81K
Feb 23, 2024	PICKERING GRANT	SALE	77.56	119	9.23K	375.81K
Feb 20, 2024	GUGGENHIME ANDREW	SALE	75.80	340	25.77K	79.47K
Feb 01, 2024	PICKERING GRANT	SALE	71.93	134	9.64K	151.15K
Feb 01, 2024	WASSIL JIM	SALE	75.28	950	71.52K	175.94K
Feb 01, 2024	EYDELMAN MIKHAIL	SALE	75.39	474	35.74K	20.71K
Jan 31, 2024	LUKATCH HEATH	SALE	71.50	5K	357.5K	5.63K
Jan 29, 2024	PICKERING GRANT	SALE	66.03	30K	1.98M	375.81K
Jan 29, 2024	LUKATCH HEATH	SALE	67.50	4K	270K	5.63K
Jan 23, 2024	PICKERING GRANT	SALE	64.78	2.04K	132.09K	375.81K
Jan 18, 2024	GUGGENHIME ANDREW	SALE	63.35	23	1.46K	79.47K
Jan 02, 2024	WASSIL JIM	SALE	65.15	110	7.17K	175.94K
Jan 02, 2024	PICKERING GRANT	SALE	64.24	643	41.3K	151.29K
Jan 02, 2024	EYDELMAN MIKHAIL	SALE	63.59	598	38.03K	21.64K
Jan 02, 2024	LUKATCH HEATH	SALE	62.85	1.1K	69.2K	17.52K
Dec 26, 2023	PICKERING GRANT	SALE	62.08	7.55K	468.68K	375.81K
Dec 18, 2023	GUGGENHIME ANDREW	SALE	60.79	117	7.11K	79.47K
Dec 14, 2023	GUGGENHIME ANDREW	SALE	60.22	14K	843.08K	79.47K
Dec 07, 2023	EYDELMAN MIKHAIL	SALE	56.50	10K	565K	21.04K
Dec 01, 2023	WASSIL JIM	SALE	51.46	1.07K	54.91K	177.87K
Dec 01, 2023	PICKERING GRANT	SALE	51.43	468	24.07K	153.44K
Nov 24, 2023	PICKERING GRANT	SALE	48.96	11.22K	549.38K	374.69K
Nov 20, 2023	GUGGENHIME ANDREW	SALE	51.12	7.88K	402.62K	79.6K
Nov 01, 2023	WASSIL JIM	SALE	47.22	2.88K	135.91K	176.06K
Nov 01, 2023	PICKERING GRANT	SALE	47.31	1.31K	61.79K	153.91K
Oct 23, 2023	PICKERING GRANT	SALE	46.98	11.24K	527.86K	389.68K
Oct 18, 2023	GUGGENHIME ANDREW	SALE	45.88	7.5K	344K	79.98K
Oct 02, 2023	PICKERING GRANT	SALE	49.67	641	31.84K	155.88K
Oct 02, 2023	EYDELMAN MIKHAIL	SALE	49.58	7.99K	396.24K	32.5K
Oct 02, 2023	WASSIL JIM	SALE	49.69	1.54K	76.62K	172.39K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES30.42K8

NET SHARES-30.42K8

SHARES HELD617.84K8

% NET SHARES-104.92%0%

Frequently Asked Questions

Stock Outstanding Shares

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares8.81

Short Percent Of Float9.86

Shares Outstanding129.82M

Shares Float116.97M

Shares Short11.44M

Short Ratio8.72

9.86%

Short % of Float

8.81%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

0.66% Percentage of Shares held by All Insiders

114.93% Percentage of Shares held by All Institutions

115.69% Percentage of Float held by Institutions

421

Number of Institutions Holding Shares

Institutional Ownership

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Dec 31, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.65%	881.44K	40.67M	-148.19K	-14.39%
Dec 31, 2025	UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH	0.05%	70.12K	3.24M	35.97K	+105.34%
Dec 31, 2025	BANQUE PICTET & CIE SA	0.05%	71.82K	3.31M	-3.05K	-4.07%
Dec 31, 2025	JUMP FINANCIAL, LLC	0.07%	89.82K	4.14M	-101.88K	-53.14%
Dec 31, 2025	SWISS NATIONAL BANK	0.17%	230.4K	10.63M	5.3K	+2.35%
Dec 31, 2025	CITIGROUP INC	0.18%	241.88K	11.16M	-71.2K	-22.74%
Dec 31, 2025	JANE STREET GROUP, LLC	0.21%	279.6K	12.9B	-64.09K	-18.65%
Dec 31, 2025	BARCLAYS PLC	0.22%	296.2K	13.67M	-97.72K	-24.81%
Dec 31, 2025	NUVEEN, LLC	0.23%	307.2K	14.17M	-177.44K	-36.61%
Dec 31, 2025	FRANKLIN RESOURCES INC	0.25%	336.14K	15.51M	37	+0.01%
Dec 31, 2025	DEUTSCHE BANK AG\	0.25%	342.89K	15.82M	-54.9K	-13.80%
Dec 31, 2025	TD ASSET MANAGEMENT INC	0.27%	363.73K	16.78M	-34.75K	-8.72%
Dec 31, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.29%	389.01K	17.95M	-9.13K	-2.29%
Dec 31, 2025	BANK OF NEW YORK MELLON CORP	0.33%	449.36K	20.73M	9.75K	+2.22%
Dec 31, 2025	ECOR1 CAPITAL, LLC	0.33%	450K	20.76M	450K	+100.00%
Dec 31, 2025	FEDERATED HERMES, INC.	0.38%	523.49K	24.15M	505.33K	+2,783.28%
Dec 31, 2025	ENSIGN PEAK ADVISORS, INC	0.39%	527.69K	24.35M	-1.17K	-0.22%
Dec 31, 2025	ASSENAGON ASSET MANAGEMENT S.A.	0.4%	544.73K	25.13M	324.78K	+147.66%
Dec 31, 2025	MORGAN STANLEY	0.61%	835.39K	38.54M	50.9K	+6.49%
Dec 31, 2025	CAPITAL RESEARCH GLOBAL INVESTORS	0.62%	842.98K	38.9M	0	0
Dec 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.95%	1.29M	59.7M	423	+0.03%
Dec 31, 2025	MAVERICK CAPITAL LTD	0.99%	1.35M	62.48M	64.67K	+5.01%
Dec 31, 2025	PIVOTAL BIOVENTURE PARTNERS INVESTMENT ADVISOR LLC	1.01%	1.37M	63.32M	0	0
Dec 31, 2025	POLAR CAPITAL HOLDINGS PLC	1.23%	1.67M	77.18M	1.26M	+302.57%
Dec 31, 2025	CALIGAN PARTNERS LP	1.25%	1.7M	78.66M	1.7M	+100.00%
Dec 31, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	1.27%	1.73M	79.59M	1.39M	+418.02%
Dec 31, 2025	KYNAM CAPITAL MANAGEMENT, LP	2.15%	2.92M	134.84M	-149.25K	-4.86%
Dec 31, 2025	D. E. SHAW & CO., INC.	2.67%	3.63M	167.54M	-659.74K	-15.38%
Dec 31, 2025	PARADIGM BIOCAPITAL ADVISORS LP	2.99%	4.07M	187.7M	283.27K	+7.48%
Dec 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	4.38%	5.97M	275.29M	933.54K	+18.55%
Dec 31, 2025	RA CAPITAL MANAGEMENT, L.P.	7.87%	10.72M	494.83M	-1.24M	-10.37%
Dec 31, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	8.29%	11.3M	521.21M	2.98M	+35.85%
Dec 31, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.37%	497.74K	22.97M	369.01K	+286.65%
Dec 31, 2025	VICTORY CAPITAL MANAGEMENT INC	0.4%	549.51K	25.35M	234.62K	+74.51%
Dec 31, 2025	BROWN ADVISORY INC	0.42%	566.93K	26.16M	-110.06K	-16.26%
Dec 31, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	0.45%	608.96K	28.1M	608.96K	+100.00%
Dec 31, 2025	JENNISON ASSOCIATES LLC	0.5%	677.55K	31.26M	-493.35K	-42.13%
Dec 31, 2025		0.29%	400.36K	18.47M	400.36K	+100.00%
Dec 31, 2025	SATURN V CAPITAL MANAGEMENT LLC	0.59%	798.94K	36.86M	10.5K	+1.33%
Dec 31, 2025	NOVO HOLDINGS A/S	0.67%	916.16K	42.27M	0	0
Dec 31, 2025	EVENTIDE ASSET MANAGEMENT, LLC	0.67%	917.12K	42.31M	537.79K	+141.77%
Dec 31, 2025	ABRDN PLC	0.72%	979.77K	45.21M	256.97K	+35.55%
Dec 31, 2025	NORTHERN TRUST CORP	0.76%	1.03M	47.72M	-39.17K	-3.65%
Dec 31, 2025	GOLDMAN SACHS GROUP INC	0.79%	1.08M	49.74M	102.74K	+10.53%
Dec 31, 2025	JPMORGAN CHASE & CO	0.8%	1.09M	50.09M	-479.52K	-30.64%
Dec 31, 2025	UBS GROUP AG	0.8%	1.09M	50.46M	246.02K	+29.03%
Dec 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	0.86%	1.18M	54.23M	-513.14K	-30.39%
Dec 31, 2025	EVERSEPT PARTNERS, LP	0.88%	1.2M	55.26M	-224.26K	-15.77%
Dec 31, 2025	JANUS HENDERSON GROUP PLC	9.83%	13.39M	617.73M	282.99K	+2.16%
Dec 31, 2025	FMR LLC	10.16%	13.83M	638.32M	1.32M	+10.59%
Dec 31, 2025	NORGES BANK	0.9%	1.23M	56.7M	1.23M	+100.00%
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.1%	2.87M	132.27M	-17.74K	-0.61%
Dec 31, 2025	WESTFIELD CAPITAL MANAGEMENT CO LP	2.6%	3.54M	163.32M	-193K	-5.17%
Dec 31, 2025	PROFUND ADVISORS LLC	0.04%	50.45K	2.33M	17.53K	+53.23%
Dec 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.04%	50.76K	2.34M	-206.91K	-80.30%
Dec 31, 2025	ENVESTNET ASSET MANAGEMENT INC	0.04%	50.8K	2.34M	-19.01K	-27.24%
Dec 31, 2025	DEEP TRACK CAPITAL, LP	2.94%	4M	184.56M	1M	+33.33%
Dec 31, 2025	STATE STREET CORP	3.66%	4.98M	229.78M	194.12K	+4.06%
Dec 31, 2025	BLACKROCK, INC.	7.52%	10.25M	472.77M	290.4K	+2.92%
Dec 31, 2025	VANGUARD GROUP INC	8.95%	12.19M	562.63M	-126.47K	-1.03%
Dec 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.07%	93.3K	4.3B	6.1K	+7.00%
Dec 31, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.08%	108.45K	4.97M	-28.43K	-20.77%
Dec 31, 2025	TWO SIGMA INVESTMENTS, LP	0.08%	111.31K	5.14B	3.72K	+3.46%
Dec 31, 2025	HRT FINANCIAL LP	0.08%	113.95K	5.26M	-84	-0.07%
Dec 31, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.09%	116.82K	5.39M	-4.97K	-4.08%
Dec 31, 2025	LEGAL & GENERAL GROUP PLC	0.09%	120.3K	5.55M	-10.1K	-7.75%
Dec 31, 2025	WELLS FARGO & COMPANY/MN	0.1%	134.08K	6.19M	8.03K	+6.37%
Dec 31, 2025	NAN FUNG TRINITY (HK) LTD	0.1%	142.93K	6.59M	38.68K	+37.10%
Dec 31, 2025	CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM	0.11%	144.6K	6.67M	-11	-0.01%
Dec 31, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.04%	58.23K	2.69M	-9.72K	-14.31%
Dec 31, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.11%	148.79K	6.87M	-165.55K	-52.67%
Dec 31, 2025	RHUMBLINE ADVISERS	0.11%	150.92K	6.96B	-32.29K	-17.63%
Dec 31, 2025	RAYMOND JAMES FINANCIAL INC	0.14%	185.85K	8.45M	-3.44K	-1.82%
Dec 31, 2025	DIMENSIONAL FUND ADVISORS LP	0.14%	191.79K	8.85M	163.42K	+576.09%
Dec 31, 2025	C WORLDWIDE GROUP HOLDING A/S	0.14%	195K	9M	0	0
Dec 31, 2025	CITADEL ADVISORS LLC	0.24%	326.57K	15.07B	120.78K	+58.69%
Dec 31, 2025	MILLENNIUM MANAGEMENT LLC	0.31%	424.29K	19.58M	-524.67K	-55.29%
Dec 31, 2025	LOGOS GLOBAL MANAGEMENT LP	0.48%	650K	29.99M	25K	+4.00%
Dec 31, 2025	BANK OF AMERICA CORP /DE/	0.52%	701.63K	32.37M	66.56K	+10.48%
Dec 31, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.05%	63.81K	2.94M	-2.76K	-4.14%
Dec 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0.05%	65.21K	3.01M	-15.27K	-18.97%
Dec 31, 2025	SEGALL BRYANT & HAMILL, LLC	0.14%	193.42K	8.92M	8.63K	+4.67%
Dec 31, 2025	ALYESKA INVESTMENT GROUP, L.P.	0.18%	244.78K	11.29M	0	0
Dec 31, 2025	UNIVERSITY OF WISCONSIN FOUNDATION	0.18%	247K	11.4M	247K	+100.00%
Dec 31, 2025	AMERICAN CENTURY COMPANIES INC	0.26%	357.3K	16.49M	13.27K	+3.86%
Sep 30, 2025	FIERA CAPITAL CORP	0.25%	345.85K	12.46M	-7.99K	-2.26%
Sep 30, 2025	AMERIPRISE FINANCIAL INC	0.28%	374.9K	13.5M	44.23K	+13.38%
Sep 30, 2025	CAPITAL RESEARCH GLOBAL INVESTORS	0.62%	842.98K	30.36M	-3.93M	-82.33%
Sep 30, 2025	FRANKLIN RESOURCES INC	0.25%	336.11K	12.11M	-603.17K	-64.22%
Sep 30, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.29%	398.14K	14.34M	-156.86K	-28.26%
Sep 30, 2025	TD ASSET MANAGEMENT INC	0.29%	398.48K	14.35M	-141.3K	-26.18%
Sep 30, 2025	POLAR CAPITAL HOLDINGS PLC	0.31%	415.53K	14.97M	-410.27K	-49.68%
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.32%	439.61K	15.83M	-10.08K	-2.24%
Sep 30, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	0.35%	474.41K	17.09M	0	0
Sep 30, 2025	ENSIGN PEAK ADVISORS, INC	0.39%	528.85K	19.05M	-3.35K	-0.63%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.47%	635.07K	22.88M	-447.6K	-41.34%
Sep 30, 2025	BAKER BROS. ADVISORS LP	0.47%	640.89K	23.08M	0	0
Sep 30, 2025	COMERICA BANK	0.48%	654.37K	23.57M	174.86K	+36.47%
Sep 30, 2025	BROWN ADVISORY INC	0.5%	676.99K	24.39M	105.05K	+18.37%
Sep 30, 2025	ABRDN PLC	0.53%	722.79K	26.04M	297.89K	+70.11%
Sep 30, 2025	MORGAN STANLEY	0.58%	784.48K	28.26M	-57.44K	-6.82%
Sep 30, 2025	SATURN V CAPITAL MANAGEMENT LLC	0.58%	788.44K	28.4M	244.22K	+44.88%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.95%	1.29M	46.59M	-124.3K	-8.77%
Sep 30, 2025	PIVOTAL BIOVENTURE PARTNERS INVESTMENT ADVISOR LLC	1.01%	1.37M	49.43M	67.3K	+5.16%
Sep 30, 2025	EVERSEPT PARTNERS, LP	1.05%	1.42M	51.22M	123.47K	+9.51%
Sep 30, 2025	JPMORGAN CHASE & CO	1.15%	1.57M	56.37M	366.27K	+30.55%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.12%	2.88M	103.9M	-127.1K	-4.22%
Sep 30, 2025	DEEP TRACK CAPITAL, LP	2.21%	3M	108.06M	850K	+39.53%
Sep 30, 2025	D. E. SHAW & CO., INC.	3.15%	4.29M	154.55M	1.2M	+38.93%
Sep 30, 2025	STATE STREET CORP	3.52%	4.79M	172.39M	-156.35K	-3.16%
Sep 30, 2025	BLACKROCK, INC.	7.32%	9.96M	358.61M	-686.27K	-6.45%
Sep 30, 2025	RA CAPITAL MANAGEMENT, L.P.	8.8%	11.97M	431.01M	0	0
Sep 30, 2025	VANGUARD GROUP INC	9.06%	12.32M	443.78M	323.37K	+2.70%
Sep 30, 2025	JANUS HENDERSON GROUP PLC	9.63%	13.1M	472.05M	-1.59M	-10.80%
Sep 30, 2025	STATE OF NEW JERSEY COMMON PENSION FUND D	0.05%	66.66K	2.4M	11.18K	+20.15%
Sep 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.05%	67.96K	2.45M	-1.81K	-2.60%
Sep 30, 2025	ENVESTNET ASSET MANAGEMENT INC	0.05%	69.81K	2.51M	-4.2K	-5.67%
Sep 30, 2025	Y-INTERCEPT (HONG KONG) LTD	0.05%	73.28K	2.64M	73.28K	+100.00%
Sep 30, 2025	BANQUE PICTET & CIE SA	0.06%	74.86K	2.7M	-8.51K	-10.20%
Sep 30, 2025	MACQUARIE GROUP LTD	0.06%	80K	2.88M	0	0
Sep 30, 2025	SCHRODER INVESTMENT MANAGEMENT GROUP	0.06%	80.24K	2.78M	1.11K	+1.41%
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.06%	80.48K	2.9M	-188.6K	-70.09%
Sep 30, 2025	NEO IVY CAPITAL MANAGEMENT	0.06%	83.11K	2.99M	58.87K	+242.85%
Sep 30, 2025	ACADIAN ASSET MANAGEMENT LLC	0.06%	84.38K	3.04M	84.38K	+100.00%
Sep 30, 2025	SEI INVESTMENTS CO	0.07%	89.95K	3.24M	50.24K	+126.52%
Sep 30, 2025	NAN FUNG TRINITY (HK) LTD	0.08%	104.25K	3.76M	0	0
Sep 30, 2025	AMERICAN CENTURY COMPANIES INC	0.25%	344.03K	12.39M	-7.03K	-2.00%
Sep 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.09%	121.79K	4.39M	-3.3K	-2.64%
Sep 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.09%	125K	4.5M	0	0
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0.09%	126.05K	4.54M	4.76K	+3.93%
Sep 30, 2025	LEGAL & GENERAL GROUP PLC	0.1%	130.4K	4.7M	-3.16K	-2.37%
Sep 30, 2025	HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND	0.1%	134.88K	4.86M	134.88K	+100.00%
Sep 30, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.11%	149.41K	5.38M	-15.41K	-9.35%
Sep 30, 2025	NOVO HOLDINGS A/S	0.67%	916.16K	33M	0	0
Sep 30, 2025	ROYAL BANK OF CANADA	0.7%	949.05K	34.18M	199.66K	+26.64%
Sep 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.24%	1.69M	60.82M	-1.48M	-46.74%
Sep 30, 2025	INVESCO LTD.	0.13%	179.08K	6.45M	17.45K	+10.79%
Sep 30, 2025	RHUMBLINE ADVISERS	0.13%	183.21K	6.6M	-15.28K	-7.70%
Sep 30, 2025	NORTHERN TRUST CORP	0.79%	1.07M	38.66M	-48.55K	-4.33%
Sep 30, 2025	SEGALL BRYANT & HAMILL, LLC	0.14%	184.8K	6.66M	4.56K	+2.53%
Sep 30, 2025	JUMP FINANCIAL, LLC	0.14%	191.7K	6.91M	-211.9K	-52.50%
Sep 30, 2025	C WORLDWIDE GROUP HOLDING A/S	0.14%	195K	7.02M	0	0
Sep 30, 2025	ASSENAGON ASSET MANAGEMENT S.A.	0.16%	219.95K	7.92M	171.97K	+358.46%
Sep 30, 2025	SWISS NATIONAL BANK	0.17%	225.1K	8.11M	3.8K	+1.72%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.19%	257.67K	9.28M	118.54K	+85.21%
Sep 30, 2025	CITIGROUP INC	0.23%	313.08K	11.28M	-116.21K	-27.07%
Sep 30, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.23%	314.34K	11.32M	26.54K	+9.22%
Sep 30, 2025	VICTORY CAPITAL MANAGEMENT INC	0.23%	314.89K	11.34M	-135.73K	-30.12%
Sep 30, 2025	KYNAM CAPITAL MANAGEMENT, LP	2.26%	3.07M	110.64M	0	0
Sep 30, 2025	WESTFIELD CAPITAL MANAGEMENT CO LP	2.74%	3.73M	134.45M	663.82K	+21.63%
Sep 30, 2025	PARADIGM BIOCAPITAL ADVISORS LP	2.78%	3.78M	136.33M	411.92K	+12.21%
Sep 30, 2025	FMR LLC	9.2%	12.51M	450.61M	358.88K	+2.95%
Sep 30, 2025	EVENTIDE ASSET MANAGEMENT, LLC	0.28%	379.33K	13.66M	-468.81K	-55.28%
Sep 30, 2025	BARCLAYS PLC	0.29%	393.91K	14.19M	-44.5K	-10.15%
Sep 30, 2025	DEUTSCHE BANK AG\	0.29%	397.79K	14.33M	134.83K	+51.28%
Sep 30, 2025	NUVEEN, LLC	0.36%	484.64K	17.46M	-3.13K	-0.64%
Sep 30, 2025	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.38%	519.73K	18.72M	-113.47K	-17.92%
Sep 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.51%	696.84K	25.1M	696.84K	+100.00%
Sep 30, 2025	MILLENNIUM MANAGEMENT LLC	0.7%	948.97K	34.18M	-155.87K	-14.11%
Sep 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.76%	1.03M	37.09M	-146.03K	-12.42%
Sep 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	3.7%	5.03M	181.28M	77.97K	+1.57%
Sep 30, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	6.11%	8.32M	299.52M	2.31M	+38.56%
Sep 30, 2025	MAVERICK CAPITAL LTD	0.95%	1.29M	46.45M	-21.04K	-1.61%
Sep 30, 2025	LOGOS GLOBAL MANAGEMENT LP	0.46%	625K	22.51M	625K	+100.00%
Sep 30, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.41%	553.85K	19.95M	-255.68K	-31.58%
Sep 30, 2025	JANE STREET GROUP, LLC	0.25%	343.7K	12.38B	45.95K	+15.43%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	0.72%	975.38K	35.13M	40.71K	+4.36%
Sep 30, 2025	JENNISON ASSOCIATES LLC	0.86%	1.17M	42.18M	-228.4K	-16.32%
Sep 30, 2025	UBS GROUP AG	0.62%	847.57K	30.53M	-533.28K	-38.62%
Jun 30, 2025	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.47%	633.2K	20.59M	633.2K	+100.00%
Jun 30, 2025	KYNAM CAPITAL MANAGEMENT, LP	2.26%	3.07M	99.86M	-128.41K	-4.01%
Jun 30, 2025	LAZARD ASSET MANAGEMENT LLC	0.38%	512.14K	16.65M	-45.66K	-8.19%
Jun 30, 2025	CITIGROUP INC	0.32%	429.28K	13.96M	-191.8K	-30.88%
Jun 30, 2025	FMR LLC	8.93%	12.15M	395.03M	-361.18K	-2.89%
Jun 30, 2025	RA CAPITAL MANAGEMENT, L.P.	8.8%	11.97M	389.01M	-223.16K	-1.83%
Jun 30, 2025	ROYAL BANK OF CANADA	0.55%	749.39K	24.36M	719.92K	+2,442.81%
Jun 30, 2025	CLEARBRIDGE INVESTMENTS, LLC	0.47%	646.06K	21M	-574.4K	-47.06%
Jun 30, 2025	BAKER BROS. ADVISORS LP	0.47%	640.89K	20.84M	0	0
Jun 30, 2025	RAYMOND JAMES FINANCIAL INC	0.22%	299.58K	9.74M	6.45K	+2.20%
Jun 30, 2025	SIREN, L.L.C.	0.22%	295.54K	9.61M	0	0
Jun 30, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.21%	287.8K	9.36M	287.8K	+100.00%
Jun 30, 2025	ALYESKA INVESTMENT GROUP, L.P.	0.18%	244.78K	7.96M	80.14K	+48.67%
Jun 30, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	0.17%	225K	7.31M	0	0
Jun 30, 2025	AQUATIC CAPITAL MANAGEMENT LLC	0.15%	206.17K	6.7M	206.17K	+100.00%
Jun 30, 2025	WOODLINE PARTNERS LP	0.15%	200.08K	6.5M	-911.7K	-82.00%
Jun 30, 2025		0.36%	487.77K	15.86M	-68.06K	-12.25%
Jun 30, 2025	C WORLDWIDE GROUP HOLDING A/S	0.14%	195K	6.34M	100K	+105.26%
Jun 30, 2025	EVENTIDE ASSET MANAGEMENT, LLC	0.62%	848.14K	27.57M	377.91K	+80.37%
Jun 30, 2025	POLAR CAPITAL HOLDINGS PLC	0.61%	825.8K	26.85M	-256.68K	-23.71%
Jun 30, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.6%	809.53K	26.32M	809.53K	+100.00%
Jun 30, 2025	TWINBEECH CAPITAL LP	0.37%	503.25K	16.36M	98.28K	+24.27%
Jun 30, 2025	COMERICA BANK	0.35%	479.51K	15.59M	119.32K	+33.13%
Jun 30, 2025	VICTORY CAPITAL MANAGEMENT INC	0.33%	450.62K	14.65M	229.8K	+104.07%
Jun 30, 2025	BANK OF NEW YORK MELLON CORP	0.33%	449.69K	14.62M	31.68K	+7.58%
Jun 30, 2025	BROWN ADVISORY INC	0.42%	571.94K	18.59M	1.68K	+0.29%
Jun 30, 2025	D. E. SHAW & CO., INC.	2.27%	3.09M	100.41B	2.22M	+255.86%
Jun 30, 2025	ABRDN PLC	0.31%	424.91K	13.81M	160.17K	+60.50%
Jun 30, 2025	JUMP FINANCIAL, LLC	0.3%	403.6K	13.12M	303.5K	+303.19%
Jun 30, 2025	WALLEYE CAPITAL LLC	0.27%	362.61K	11.79M	256.64K	+242.19%
Jun 30, 2025	FIERA CAPITAL CORP	0.26%	353.84K	11.5M	-5.36K	-1.49%
Jun 30, 2025	AMERICAN CENTURY COMPANIES INC	0.26%	351.05K	11.41M	-236K	-40.20%
Jun 30, 2025	IKARIAN CAPITAL, LLC	0.22%	305K	9.92M	105K	+52.50%
Jun 30, 2025	TANG CAPITAL MANAGEMENT LLC	0.22%	300K	9.75M	0	0
Jun 30, 2025	SEGALL BRYANT & HAMILL, LLC	0.13%	180.24K	5.86M	30.48K	+20.35%
Jun 30, 2025	CORMORANT ASSET MANAGEMENT, LP	0.13%	175K	5.69M	0	0
Jun 30, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.41%	555.01K	18.04M	41.01K	+7.98%
Jun 30, 2025	BARCLAYS PLC	0.32%	438.41K	14.25M	212.29K	+93.88%
Jun 30, 2025	BLACKROCK, INC.	7.82%	10.64M	345.98M	62.77K	+0.59%
Jun 30, 2025	DEEP TRACK CAPITAL, LP	1.58%	2.15M	69.9M	1.4M	+186.67%
Jun 30, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	4.41%	6M	195.1M	3.3M	+122.04%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	1.04%	1.42M	46.09M	84.33K	+6.32%
Jun 30, 2025	JENNISON ASSOCIATES LLC	1.03%	1.4M	45.49M	273.58K	+24.30%
Jun 30, 2025	NORTHERN TRUST CORP	0.82%	1.12M	36.47M	-1.06K	-0.09%
Jun 30, 2025	MILLENNIUM MANAGEMENT LLC	0.81%	1.1M	35.92M	691.41K	+167.24%
Jun 30, 2025	FRANKLIN RESOURCES INC	0.69%	939.28K	30.54M	-2.15M	-69.59%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0.8%	1.08M	35.2M	291.86K	+36.91%
Jun 30, 2025	WESTFIELD CAPITAL MANAGEMENT CO LP	2.26%	3.07M	99.77M	913.76K	+42.40%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.21%	3.01M	97.9M	142.09K	+4.95%
Jun 30, 2025	MAVERICK CAPITAL LTD	0.96%	1.31M	42.61M	102.51K	+8.49%
Jun 30, 2025	PIVOTAL BIOVENTURE PARTNERS INVESTMENT ADVISOR LLC	0.96%	1.31M	42.43M	594.39K	+83.63%
Jun 30, 2025	EVERSEPT PARTNERS, LP	0.95%	1.3M	42.21M	741.44K	+133.10%
Jun 30, 2025	JPMORGAN CHASE & CO	0.88%	1.2M	38.97M	-701.41K	-36.91%
Jun 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.86%	1.18M	38.23M	124.98K	+11.90%
Jun 30, 2025	NORGES BANK	0.73%	987.67K	32.11M	987.67K	+100.00%
Jun 30, 2025	NOVO HOLDINGS A/S	0.67%	916.16K	29.78M	1.16K	+0.13%
Jun 30, 2025	SATURN V CAPITAL MANAGEMENT LLC	0.4%	544.22K	17.69M	311.93K	+134.28%
Jun 30, 2025	TD ASSET MANAGEMENT INC	0.4%	539.78K	17.55M	236.19K	+77.80%
Jun 30, 2025	ENSIGN PEAK ADVISORS, INC	0.39%	532.2K	17.3M	-211.96K	-28.48%
Jun 30, 2025	JANUS HENDERSON GROUP PLC	10.8%	14.69M	477.66M	2.93M	+24.87%
Jun 30, 2025	UBS GROUP AG	1.02%	1.38M	44.89M	300.46K	+27.81%
Jun 30, 2025	CITADEL ADVISORS LLC	0.8%	1.09M	35.46B	994.35K	+1,031.62%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.69%	934.67K	30.39B	-212.63K	-18.53%
Jun 30, 2025	MORGAN STANLEY	0.62%	841.92K	27.37B	234.97K	+38.71%
Jun 30, 2025	NUVEEN, LLC	0.36%	487.77K	15.86M	-68.06K	-12.25%
Jun 30, 2025	VANGUARD GROUP INC	8.82%	12M	390.03M	-46.72K	-0.39%
Jun 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	3.64%	4.95M	161.08M	-1.46M	-22.79%
Jun 30, 2025	STATE STREET CORP	3.63%	4.94M	160.67M	534.55K	+12.13%
Jun 30, 2025	CAPITAL RESEARCH GLOBAL INVESTORS	3.51%	4.77M	155.13M	-1.34M	-21.90%
Jun 30, 2025	PARADIGM BIOCAPITAL ADVISORS LP	2.48%	3.37M	109.65M	1.68M	+98.81%
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	2.33%	3.17M	103.07M	-371.76K	-10.50%
Jun 30, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	0.35%	474.41K	15.42M	-65K	-12.05%
Mar 31, 2025	UBS GROUP AG	0.8%	1.08M	40.8M	343.84K	+46.68%
Mar 31, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	0.78%	1.06M	40.06M	-105.97K	-9.08%
Mar 31, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.77%	1.05M	42.17M	32.83K	+3.23%
Mar 31, 2025		0.41%	555.83K	20.99M	555.83K	+100.00%
Mar 31, 2025	EVERSEPT PARTNERS, LP	0.41%	557.07K	21.03M	429.48K	+336.62%
Mar 31, 2025	BROWN ADVISORY INC	0.42%	570.26K	21.53M	14.05K	+2.53%
Mar 31, 2025	CLEARBRIDGE INVESTMENTS, LLC	0.9%	1.22M	46.08M	117.97K	+10.70%
Mar 31, 2025	INVESCO LTD.	0.93%	1.26M	47.42M	89.77K	+7.70%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.98%	1.33M	50.35M	-8.39K	-0.63%
Mar 31, 2025	ALLIANCEBERNSTEIN L.P.	1.26%	1.7M	64.35M	-75.15K	-4.22%
Mar 31, 2025	JPMORGAN CHASE & CO	1.4%	1.9M	71.75M	164.52K	+9.48%
Mar 31, 2025	CITIGROUP INC	0.46%	621.08K	23.45M	241.87K	+63.78%
Mar 31, 2025	BAKER BROS. ADVISORS LP	0.47%	640.89K	24.2M	592K	+1,211.01%
Mar 31, 2025	AMERIPRISE FINANCIAL INC	0.5%	678.58K	25.61M	-38.19K	-5.33%
Mar 31, 2025	PERCEPTIVE ADVISORS LLC	0.52%	706.57K	26.68M	-1.01M	-58.88%
Mar 31, 2025	PIVOTAL BIOVENTURE PARTNERS INVESTMENT ADVISOR LLC	0.52%	710.73K	26.84M	6.9K	+0.98%
Mar 31, 2025	DEEP TRACK CAPITAL, LP	0.55%	750K	28.32M	750K	+100.00%
Mar 31, 2025	HOOD RIVER CAPITAL MANAGEMENT LLC	0.55%	751.61K	28.38M	350.17K	+87.23%
Mar 31, 2025	D. E. SHAW & CO., INC.	0.64%	867.89K	32.77M	92.24K	+11.89%
Mar 31, 2025	POLAR CAPITAL HOLDINGS PLC	0.8%	1.08M	40.87M	108.83K	+11.18%
Mar 31, 2025	WOODLINE PARTNERS LP	0.82%	1.11M	41.98M	-9.15K	-0.82%
Mar 31, 2025	NORTHERN TRUST CORP	0.83%	1.12M	42.4M	-37.05K	-3.19%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.85%	1.15M	43.32M	-1.98M	-63.34%
Mar 31, 2025	DEUTSCHE BANK AG\	0.88%	1.2M	45.22M	-15.02K	-1.24%
Mar 31, 2025	PARADIGM BIOCAPITAL ADVISORS LP	1.25%	1.7M	64.06M	273.69K	+19.24%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.11%	2.87M	108.36M	66.17K	+2.36%
Mar 31, 2025	WESTFIELD CAPITAL MANAGEMENT CO LP	1.59%	2.16M	81.38M	-411.62K	-16.04%
Mar 31, 2025	KYNAM CAPITAL MANAGEMENT, LP	2.36%	3.2M	120.83M	863.2K	+36.94%
Mar 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	2.61%	3.54M	133.75M	-424.95K	-10.71%
Mar 31, 2025	CAPITAL RESEARCH GLOBAL INVESTORS	4.5%	6.11M	230.72M	-100.42K	-1.62%
Mar 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	4.73%	6.42M	242.3M	1.97M	+44.40%
Mar 31, 2025	AVORO CAPITAL ADVISORS LLC	0.74%	1M	37.76M	-175K	-14.89%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0.58%	790.81K	29.86M	320.9K	+68.29%
Mar 31, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	1.99%	2.7M	102.05M	-158.03K	-5.52%
Mar 31, 2025	BLACKROCK, INC.	7.8%	10.58M	399.48M	-526.59K	-4.74%
Mar 31, 2025	JANUS HENDERSON GROUP PLC	8.67%	11.77M	815.87M	1.19M	+11.25%
Mar 31, 2025	VANGUARD GROUP INC	8.88%	12.04M	454.77M	82.12K	+0.69%
Mar 31, 2025	STATE STREET CORP	3.25%	4.41M	166.43M	-131.72K	-2.90%
Mar 31, 2025	RA CAPITAL MANAGEMENT, L.P.	8.98%	12.19M	460.26M	3.5M	+40.28%
Mar 31, 2025	COMMODORE CAPITAL LP	1.22%	1.65M	62.3M	25K	+1.54%
Mar 31, 2025	FRANKLIN RESOURCES INC	2.28%	3.09M	116.64M	219.7K	+7.66%
Mar 31, 2025	AMERICAN CENTURY COMPANIES INC	0.43%	587.05K	22.17M	-18.21K	-3.01%
Mar 31, 2025	ENSIGN PEAK ADVISORS, INC	0.55%	744.16K	28.1M	158.03K	+26.96%
Mar 31, 2025	JENNISON ASSOCIATES LLC	0.83%	1.13M	42.51M	-120.83K	-9.69%
Mar 31, 2025	MAVERICK CAPITAL LTD	0.89%	1.21M	45.62M	6.2K	+0.52%
Mar 31, 2025	FMR LLC	9.22%	12.51M	472.46M	-579.41K	-4.43%
Mar 31, 2025	LAZARD ASSET MANAGEMENT LLC	0.41%	557.79K	21.06M	71.03K	+14.59%
Mar 31, 2025	NOVO HOLDINGS A/S	0.67%	915K	34.55M	165K	+22.00%
Mar 31, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	0.4%	539.41K	20.37M	0	0
Mar 31, 2025	MORGAN STANLEY	0.45%	606.95K	22.92M	-86.38K	-12.46%
Mar 31, 2024	BLACKROCK INC.	9.79%	9.51M	649.83M	937.16K	+10.93%
Mar 31, 2024	AMUNDI	0.31%	302.36K	18.33M	-27.43K	-8.32%
Mar 31, 2024	SAMLYN CAPITAL, LLC	0.31%	302.68K	20.68M	-26.53K	-8.06%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.32%	311.35K	21.27M	30.5K	+10.86%
Mar 31, 2024	EAGLE ASSET MANAGEMENT INC	0.35%	338.8K	22.61M	-15.32K	-4.33%
Mar 31, 2024	MAVERICK CAPITAL LTD	0.37%	355.13K	24.26M	355.13K	+100.00%
Mar 31, 2024	D. E. SHAW & CO., INC.	0.38%	367.25K	25.09M	-71.06K	-16.21%
Mar 31, 2024	FARALLON CAPITAL MANAGEMENT LLC	0.39%	377.4K	25.78M	374K	+11,000.00%
Mar 31, 2024	ENSIGN PEAK ADVISORS, INC	0.49%	475.7K	32.5M	114.57K	+31.73%
Mar 31, 2024	MORGAN STANLEY	0.5%	490.45K	33.5M	-46.91K	-8.73%
Mar 31, 2024	AVORO CAPITAL ADVISORS LLC	0.59%	575K	39.28M	575K	+100.00%
Mar 31, 2024	EVENTIDE ASSET MANAGEMENT, LLC	0.68%	657.21K	44.89M	50K	+8.23%
Mar 31, 2024	CORMORANT ASSET MANAGEMENT, LP	0.71%	685K	46.79M	20K	+3.01%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.72%	698.49K	47.71M	217.37K	+45.18%
Mar 31, 2024	KYNAM CAPITAL MANAGEMENT, LP	0.77%	745K	50.89M	-257.41K	-25.68%
Mar 31, 2024	PIVOTAL BIOVENTURE PARTNERS INVESTMENT ADVISOR LLC	0.82%	793.04K	54.17M	0	0
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.86%	833.62K	56.94M	103.18K	+14.13%
Mar 31, 2024	NOVO HOLDINGS A/S	0.87%	845K	57.72M	0	0
Mar 31, 2024	COMMODORE CAPITAL LP	0.89%	860K	58.75M	-240K	-21.82%
Mar 31, 2024	PICTET ASSET MANAGEMENT HOLDING SA	0.89%	861.57K	58.85M	-287.64K	-25.03%
Mar 31, 2024	NORTHERN TRUST CORP	1%	968.76K	66.18M	84.49K	+9.55%
Mar 31, 2024	ORBIMED ADVISORS LLC	1.1%	1.07M	72.83M	-86.96K	-7.54%
Mar 31, 2024	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	1.17%	1.14M	77.83M	-25K	-2.15%
Mar 31, 2024	JPMORGAN CHASE & CO	1.2%	1.16M	79.36M	756.44K	+186.62%
Mar 31, 2024	BRAIDWELL LP	1.25%	1.21M	82.84M	-77.26K	-5.99%
Mar 31, 2024	INVESCO LTD.	1.27%	1.23M	84.33M	1.01M	+443.95%
Mar 31, 2024	FMR LLC	16.74%	16.26M	1.11B	2.05M	+14.41%
Mar 31, 2024	PARADIGM BIOCAPITAL ADVISORS LP	1.28%	1.24M	84.7M	1.24M	+100.00%
Mar 31, 2024	JENNISON ASSOCIATES LLC	1.29%	1.26M	85.86M	-219.27K	-14.85%
Mar 31, 2024	FRED ALGER MANAGEMENT, LLC	1.44%	1.4M	95.41M	-273.48K	-16.37%
Mar 31, 2024	WESTFIELD CAPITAL MANAGEMENT CO LP	1.63%	1.59M	108.35M	130.5K	+8.97%
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	1.83%	1.78M	121.64M	-134.34K	-7.02%
Mar 31, 2024	DRIEHAUS CAPITAL MANAGEMENT LLC	1.92%	1.87M	127.59M	193.44K	+11.55%
Mar 31, 2024	PERCEPTIVE ADVISORS LLC	1.99%	1.93M	132.03M	844.27K	+77.56%
Mar 31, 2024	FRANKLIN RESOURCES INC	2.21%	2.15M	146.71M	1.07M	+99.43%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	2.35%	2.29M	156.27M	313.87K	+15.90%
Mar 31, 2024	DARWIN GLOBAL MANAGEMENT, LTD.	2.83%	2.75M	187.91M	2.17M	+374.31%
Mar 31, 2024	CAPITAL RESEARCH GLOBAL INVESTORS	4.26%	4.14M	282.84M	700.41K	+20.36%
Mar 31, 2024	WELLINGTON MANAGEMENT GROUP LLP	5.06%	4.92M	336.04M	487.45K	+11.00%
Mar 31, 2024	RA CAPITAL MANAGEMENT, L.P.	8.44%	8.2M	560.4M	312.5K	+3.96%
Mar 31, 2024	VANGUARD GROUP INC	10.02%	9.74M	665.15M	1.28M	+15.20%
Mar 31, 2024	LORD, ABBETT & CO. LLC	0.4%	384.36K	26.26M	-1.21K	-0.31%
Mar 31, 2024	WOODLINE PARTNERS LP	0.41%	393.7K	26.89M	353	+0.09%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.42%	412.53K	28.18M	13.41K	+3.36%
Mar 31, 2024	FEDERATED HERMES, INC.	0.44%	425.75K	29.08M	31.56K	+8.01%
Mar 31, 2024	AMERICAN CENTURY COMPANIES INC	0.48%	461.72K	31.54M	54.5K	+13.38%
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	3.27%	3.18M	216.97M	498.36K	+18.61%
Mar 31, 2024	STATE STREET CORP	3.43%	3.34M	227.96M	-52.44K	-1.55%
Mar 31, 2024	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	3.66%	3.55M	242.7M	2.31M	+185.14%
Mar 31, 2024	STATE OF WISCONSIN INVESTMENT BOARD	0.06%	60.68K	4.14M	3.49K	+6.09%
Mar 31, 2024	BANQUE PICTET & CIE SA	0.06%	60.89K	4.16M	60.89K	+100.00%
Mar 31, 2024	FIRST TRUST ADVISORS LP	0.07%	63.83K	4.36M	-13.81K	-17.79%
Mar 31, 2024	RAYMOND JAMES & ASSOCIATES	0.07%	66.33K	4.53M	14.78K	+28.67%
Mar 31, 2024	ALPS ADVISORS INC	0.08%	76.32K	5.21M	11.02K	+16.88%
Mar 31, 2024	AFFINITY ASSET ADVISORS, LLC	0.08%	80K	5.46M	55K	+220.00%
Mar 31, 2024	NICHOLAS INVESTMENT PARTNERS, LP	0.09%	85.64K	5.85M	-25.08K	-22.65%
Mar 31, 2024	LEGAL & GENERAL GROUP PLC	0.1%	94.78K	6.47B	14.78K	+18.47%
Mar 31, 2024	MONASHEE INVESTMENT MANAGEMENT LLC	0.1%	100K	6.83M	62.5K	+166.67%
Mar 31, 2024	NEUBERGER BERMAN GROUP LLC	0.11%	102.31K	6.99M	16.14K	+18.74%
Mar 31, 2024	SEI INVESTMENTS CO	0.11%	103.4K	7.06B	55	+0.05%
Mar 31, 2024	CAPSTONE INVESTMENT ADVISORS, LLC	0.11%	109.39K	7.47M	109.39K	+100.00%
Mar 31, 2024	MOODY ALDRICH PARTNERS LLC	0.12%	118.6K	8.1M	-29.33K	-19.82%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.12%	119.08K	8.13M	14.01K	+13.33%
Mar 31, 2024	CREDIT SUISSE AG/	0.13%	123.97K	8.47M	26.17K	+26.75%
Mar 31, 2024	RAFFERTY ASSET MANAGEMENT, LLC	0.13%	126.16K	8.62M	-32.25K	-20.36%
Mar 31, 2024	PIER CAPITAL, LLC	0.13%	127.38K	8.7M	-74.18K	-36.80%
Mar 31, 2024	CITIGROUP INC	0.15%	144.87K	9.9M	65.96K	+83.58%
Mar 31, 2024	RHUMBLINE ADVISERS	0.15%	148.29K	10.13M	17.74K	+13.59%
Mar 31, 2024	CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM	0.16%	156.99K	10.72M	58.85K	+59.97%
Mar 31, 2024	UBS GROUP AG	0.18%	176.08K	12.03M	10.04K	+6.05%
Mar 31, 2024	SWISS NATIONAL BANK	0.18%	178K	12.16M	30.1K	+20.35%
Mar 31, 2024	ABRDN PLC	0.2%	194.23K	13.27M	0	0
Mar 31, 2024	FIRST TURN MANAGEMENT, LLC	0.27%	260.28K	17.78M	-97.25K	-27.20%
Mar 31, 2024	CERCANO MANAGEMENT LLC	0.28%	272.15K	18.59M	272.15K	+100.00%
Mar 31, 2024	VICTORY CAPITAL MANAGEMENT INC	0.29%	280.88K	19.19M	-98.53K	-25.97%
Mar 31, 2024	TD ASSET MANAGEMENT INC	0.29%	281.29K	19.21B	114.25K	+68.40%
Mar 31, 2024	JANUS HENDERSON GROUP PLC	7.9%	7.67M	524.12M	692.49K	+9.92%
Dec 31, 2023	DRIEHAUS CAPITAL MANAGEMENT LLC	1.65%	1.67M	105.15M	350.48K	+26.47%
Dec 31, 2023	ALLIANCEBERNSTEIN L.P.	1.88%	1.92M	120.26M	-28.78K	-1.48%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.94%	1.97M	123.95M	98.39K	+5.25%
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	2.63%	2.68M	168.17M	260.17K	+10.76%
Dec 31, 2023	STATE STREET CORP	3.33%	3.39M	212.86M	244.27K	+7.77%
Dec 31, 2023	CAPITAL RESEARCH GLOBAL INVESTORS	3.38%	3.44M	216.04M	75.98K	+2.26%
Dec 31, 2023	WELLINGTON MANAGEMENT GROUP LLP	4.36%	4.43M	278.32M	4.43M	+100.00%
Dec 31, 2023	JANUS HENDERSON GROUP PLC	6.87%	6.98M	438.41M	-79.21K	-1.12%
Dec 31, 2023	RA CAPITAL MANAGEMENT, L.P.	7.76%	7.89M	495.57M	0	0
Dec 31, 2023	VANGUARD GROUP INC	8.31%	8.45M	530.81M	168.13K	+2.03%
Dec 31, 2023	BLACKROCK INC.	8.44%	8.58M	538.56M	1.15M	+15.56%
Dec 31, 2023	FMR LLC	13.98%	14.21M	892.6M	136.33K	+0.97%
Dec 31, 2023	EAGLE ASSET MANAGEMENT INC	0.35%	354.12K	22.24M	-885	-0.25%
Dec 31, 2023	GREAT POINT PARTNERS LLC	0.35%	360K	22.61M	-171.21K	-32.23%
Dec 31, 2023	ENSIGN PEAK ADVISORS, INC	0.36%	361.13K	22.68M	85.35K	+30.95%
Dec 31, 2023		0.35%	357.53K	22.45M	357.53K	+100.00%
Dec 31, 2023	VICTORY CAPITAL MANAGEMENT INC	0.37%	379.41K	23.83M	-51.54K	-11.96%
Dec 31, 2023	LORD, ABBETT & CO. LLC	0.38%	385.57K	24.21M	385.57K	+100.00%
Dec 31, 2023	WOODLINE PARTNERS LP	0.39%	393.35K	24.7M	12.74K	+3.35%
Dec 31, 2023	FEDERATED HERMES, INC.	0.39%	394.19K	24.76M	-1.62K	-0.41%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.39%	399.12K	25.06M	3.09K	+0.78%
Dec 31, 2023	PERCEPTIVE ADVISORS LLC	1.07%	1.09M	68.36M	-254.27K	-18.94%
Dec 31, 2023	COMMODORE CAPITAL LP	1.08%	1.1M	69.08M	0	0
Dec 31, 2023	ORBIMED ADVISORS LLC	1.13%	1.15M	72.41M	145.94K	+14.49%
Dec 31, 2023	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	1.15%	1.16M	73.12M	0	0
Dec 31, 2023	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	1.23%	1.25M	78.25M	41.41K	+3.44%
Dec 31, 2023	BRAIDWELL LP	1.27%	1.29M	81.01M	-329.59K	-20.35%
Dec 31, 2023	WESTFIELD CAPITAL MANAGEMENT CO LP	1.43%	1.46M	91.41M	451.68K	+44.99%
Dec 31, 2023	FRANKLIN RESOURCES INC	1.06%	1.08M	67.63M	120.99K	+12.66%
Dec 31, 2023	KYNAM CAPITAL MANAGEMENT, LP	0.99%	1M	62.95M	-300K	-23.03%
Dec 31, 2023	NORGES BANK	0.9%	915.51K	57.49M	915.51K	+100.00%
Dec 31, 2023	NORTHERN TRUST CORP	0.87%	884.27K	55.53M	-12.37K	-1.38%
Dec 31, 2023	NOVO HOLDINGS A/S	0.83%	845K	53.07M	0	0
Dec 31, 2023	PIVOTAL BIOVENTURE PARTNERS INVESTMENT ADVISOR LLC	0.78%	793.04K	49.8M	0	0
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.72%	730.44K	45.87M	17.57K	+2.46%
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	0.68%	691.43K	43.42M	108.56K	+18.63%
Dec 31, 2023	CORMORANT ASSET MANAGEMENT, LP	0.65%	665K	41.76M	0	0
Dec 31, 2023	EVENTIDE ASSET MANAGEMENT, LLC	0.6%	607.21K	38.13M	214.21K	+54.51%
Dec 31, 2023	DARWIN GLOBAL MANAGEMENT, LTD.	0.57%	579.96K	36.42M	579.96K	+100.00%
Dec 31, 2023	AVIDITY PARTNERS MANAGEMENT LP	0.56%	570.14K	35.8M	-186.03K	-24.60%
Dec 31, 2023	MORGAN STANLEY	0.53%	537.37K	33.75M	127.82K	+31.21%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.47%	481.12K	30.21M	52.01K	+12.12%
Dec 31, 2023	D. E. SHAW & CO., INC.	0.43%	438.31K	27.53M	-100.07K	-18.59%
Dec 31, 2023	SOLEUS CAPITAL MANAGEMENT, L.P.	0.41%	415.45K	26.09M	-84.2K	-16.85%
Dec 31, 2023	AMERICAN CENTURY COMPANIES INC	0.4%	407.23K	25.57M	35.49K	+9.55%
Dec 31, 2023	JPMORGAN CHASE & CO	0.4%	405.33K	25.45M	-232.39K	-36.44%
Dec 31, 2023	JENNISON ASSOCIATES LLC	1.45%	1.48M	92.7M	-278.54K	-15.87%
Dec 31, 2023	FRED ALGER MANAGEMENT, LLC	1.64%	1.67M	104.89M	-423.12K	-20.21%

Insiders

Insiders	Designation	Shares Held
WASSIL JIM	CHIEF OPERATING OFFICER	160.74K
PICKERING GRANT	CHIEF EXECUTIVE OFFICER	136.22K
GUGGENHIME ANDREW	PRESIDENT AND CFO	109.49K
EYDELMAN MIKHAIL	SVP, GEN COUNSEL & CORP SEC	41.62K
COWAN ELVIA	SVP, Finance & CAO	28.98K
DHALIWAL HARPREET S.	Chief Technical Ops Officer	23.93K
LOXAM TERI	director	7.18K
LUKATCH HEATH	director	5.63K
GILBERT HALLEY E	director	5.63K

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
May 01, 2026	WASSIL JIM	SALE	56.83	2.25K	127.87K	160.74K
Apr 07, 2026	COWAN ELVIA	SALE	60.00	3K	180K	28.98K
Apr 01, 2026	WASSIL JIM	SALE	58.93	838	49.39K	162.99K
Mar 17, 2026	COWAN ELVIA	SALE	56.26	405	22.79K	28.98K
Mar 11, 2026	COWAN ELVIA	SALE	58.59	2.5K	146.48K	30.87K
Mar 10, 2026	WASSIL JIM	SALE	59.16	4.97K	293.91K	166.82K
Dec 31, 2025	DHALIWAL HARPREET S.	SALE	46.69	9.74K	454.89K	23.93K
Dec 23, 2025	COWAN ELVIA	SALE	47.94	6.72K	321.93K	14.53K
Mar 05, 2025	EYDELMAN MIKHAIL	SALE	72.37	112	8.11K	41.62K
Mar 03, 2025	WASSIL JIM	SALE	73.84	2.09K	153.95K	154.93K
Feb 18, 2025	GUGGENHIME ANDREW	SALE	84.58	1.82K	153.77K	109.49K
Feb 05, 2025	EYDELMAN MIKHAIL	SALE	91.71	255	23.39K	28.22K
Feb 03, 2025	WASSIL JIM	SALE	87.94	20	1.76K	205.7K
Jan 21, 2025	GUGGENHIME ANDREW	SALE	87.70	683	59.9K	109.49K
Jan 15, 2025	LOXAM TERI	SALE	88.54	529	46.84K	7.18K
Jan 06, 2025	EYDELMAN MIKHAIL	SALE	86.52	125	10.82K	28.22K
Jan 02, 2025	WASSIL JIM	SALE	84.43	1.16K	98.02K	205.7K
Dec 18, 2024	GUGGENHIME ANDREW	SALE	90.24	280	25.27K	109.49K
Dec 09, 2024	PICKERING GRANT	SALE	93.10	222	20.67K	136.22K
Dec 05, 2024	EYDELMAN MIKHAIL	SALE	92.90	388	36.05K	28.7K
Dec 02, 2024	PICKERING GRANT	SALE	94.06	2.24K	210.88K	450.3K
Dec 02, 2024	WASSIL JIM	SALE	94.06	1.13K	106.01K	205.7K
Nov 18, 2024	GUGGENHIME ANDREW	SALE	87.05	132	11.49K	109.49K
Nov 05, 2024	EYDELMAN MIKHAIL	SALE	107.50	1.27K	136.84K	28.62K
Nov 01, 2024	PICKERING GRANT	SALE	108.50	1.73K	188.03K	435.22K
Nov 01, 2024	WASSIL JIM	SALE	108.93	240	26.14K	205.7K
Oct 18, 2024	GUGGENHIME ANDREW	SALE	116.19	5.89K	683.9K	90.38K
Oct 07, 2024	EYDELMAN MIKHAIL	SALE	111.68	67	7.48K	28.62K
Oct 07, 2024	PICKERING GRANT	SALE	110.20	537	59.18K	138.58K
Oct 01, 2024	WASSIL JIM	SALE	114.95	2.34K	268.86K	200.65K
Oct 01, 2024	EYDELMAN MIKHAIL	SALE	115.01	1.03K	118.46K	28.62K
Oct 01, 2024	PICKERING GRANT	SALE	114.98	5.47K	629.41K	450.22K
Sep 18, 2024	GUGGENHIME ANDREW	SALE	117.53	829	97.43K	90.38K
Sep 17, 2024	LOXAM TERI	SALE	117.51	256	30.08K	7.18K
Sep 16, 2024	WASSIL JIM	SALE	116.96	222	25.97K	200.65K
Sep 03, 2024	EYDELMAN MIKHAIL	SALE	117.28	80	9.38K	30.83K
Sep 03, 2024	COWAN ELVIA	SALE	107.67	5K	538.35K	12.72K
Sep 03, 2024	WASSIL JIM	SALE	117.03	10	1.17K	207.5K
Aug 23, 2024	PICKERING GRANT	SALE	79.25	8.31K	658.91K	478.89K
Aug 19, 2024	GUGGENHIME ANDREW	SALE	79.14	3.01K	237.88K	96.72K
Aug 01, 2024	EYDELMAN MIKHAIL	SALE	79.29	185	14.67K	30.83K
Aug 01, 2024	WASSIL JIM	SALE	79.47	23	1.83K	207.5K
Aug 01, 2024	PICKERING GRANT	SALE	78.78	1.31K	103.05K	142.13K
Jul 23, 2024	PICKERING GRANT	SALE	84.53	9.28K	784.59K	478.89K
Jul 18, 2024	GUGGENHIME ANDREW	SALE	83.14	926	76.98K	96.72K
Jul 16, 2024	COWAN ELVIA	SALE	85.00	5K	425K	12.72K
Jul 08, 2024	COWAN ELVIA	SALE	80.00	5K	400K	12.72K
Jul 01, 2024	PICKERING GRANT	SALE	76.89	557	42.83K	143.44K
Jul 01, 2024	EYDELMAN MIKHAIL	SALE	76.90	754	57.98K	30.83K
Jul 01, 2024	WASSIL JIM	SALE	77.22	111	8.57K	210.5K
Jun 24, 2024	PICKERING GRANT	SALE	76.80	188	14.44K	478.89K
Jun 18, 2024	GUGGENHIME ANDREW	SALE	72.56	348	25.25K	96.72K
Jun 03, 2024	EYDELMAN MIKHAIL	SALE	73.64	260	19.15K	31.16K
Jun 03, 2024	PICKERING GRANT	SALE	73.46	117	8.59K	144.75K
Jun 03, 2024	GILBERT HALLEY E	SALE	73.00	18.2K	1.33M	5.63K
Jun 03, 2024	WASSIL JIM	SALE	73.47	460	33.8K	213.5K
May 23, 2024	PICKERING GRANT	SALE	69.84	8.79K	613.82K	477.85K
May 20, 2024	GUGGENHIME ANDREW	SALE	75.46	4.46K	336.25K	95.68K
May 01, 2024	EYDELMAN MIKHAIL	SALE	63.90	144	9.2K	30.6K
May 01, 2024	WASSIL JIM	SALE	63.65	185	11.77K	215.46K
May 01, 2024	PICKERING GRANT	SALE	63.84	46	2.94K	146.05K
Apr 23, 2024	PICKERING GRANT	SALE	61.92	15K	928.85K	477.85K
Apr 18, 2024	GUGGENHIME ANDREW	SALE	61.90	376	23.28K	95.68K
Apr 01, 2024	WASSIL JIM	SALE	67.23	677	45.51K	218.29K
Apr 01, 2024	EYDELMAN MIKHAIL	SALE	67.42	270	18.2K	30.6K
Apr 01, 2024	PICKERING GRANT	SALE	68.10	3	204.3	147.36K
Mar 25, 2024	PICKERING GRANT	SALE	67.50	1.55K	104.62K	477.85K
Mar 18, 2024	GUGGENHIME ANDREW	SALE	69.64	236	16.44K	95.68K
Mar 01, 2024	PICKERING GRANT	SALE	74.69	363	27.11K	148.67K
Mar 01, 2024	COWAN ELVIA	SALE	74.90	4.9K	367.08K	12.48K
Mar 01, 2024	EYDELMAN MIKHAIL	SALE	74.77	445	33.27K	31.21K
Mar 01, 2024	WASSIL JIM	SALE	74.69	763	56.99K	220.85K
Feb 26, 2024	PICKERING GRANT	SALE	79.03	30K	2.37M	375.81K
Feb 23, 2024	PICKERING GRANT	SALE	77.56	119	9.23K	375.81K
Feb 20, 2024	GUGGENHIME ANDREW	SALE	75.80	340	25.77K	79.47K
Feb 01, 2024	PICKERING GRANT	SALE	71.93	134	9.64K	151.15K
Feb 01, 2024	WASSIL JIM	SALE	75.28	950	71.52K	175.94K
Feb 01, 2024	EYDELMAN MIKHAIL	SALE	75.39	474	35.74K	20.71K
Jan 31, 2024	LUKATCH HEATH	SALE	71.50	5K	357.5K	5.63K
Jan 29, 2024	PICKERING GRANT	SALE	66.03	30K	1.98M	375.81K
Jan 29, 2024	LUKATCH HEATH	SALE	67.50	4K	270K	5.63K
Jan 23, 2024	PICKERING GRANT	SALE	64.78	2.04K	132.09K	375.81K
Jan 18, 2024	GUGGENHIME ANDREW	SALE	63.35	23	1.46K	79.47K
Jan 02, 2024	WASSIL JIM	SALE	65.15	110	7.17K	175.94K
Jan 02, 2024	PICKERING GRANT	SALE	64.24	643	41.3K	151.29K
Jan 02, 2024	EYDELMAN MIKHAIL	SALE	63.59	598	38.03K	21.64K
Jan 02, 2024	LUKATCH HEATH	SALE	62.85	1.1K	69.2K	17.52K
Dec 26, 2023	PICKERING GRANT	SALE	62.08	7.55K	468.68K	375.81K
Dec 18, 2023	GUGGENHIME ANDREW	SALE	60.79	117	7.11K	79.47K
Dec 14, 2023	GUGGENHIME ANDREW	SALE	60.22	14K	843.08K	79.47K
Dec 07, 2023	EYDELMAN MIKHAIL	SALE	56.50	10K	565K	21.04K
Dec 01, 2023	WASSIL JIM	SALE	51.46	1.07K	54.91K	177.87K
Dec 01, 2023	PICKERING GRANT	SALE	51.43	468	24.07K	153.44K
Nov 24, 2023	PICKERING GRANT	SALE	48.96	11.22K	549.38K	374.69K
Nov 20, 2023	GUGGENHIME ANDREW	SALE	51.12	7.88K	402.62K	79.6K
Nov 01, 2023	WASSIL JIM	SALE	47.22	2.88K	135.91K	176.06K
Nov 01, 2023	PICKERING GRANT	SALE	47.31	1.31K	61.79K	153.91K
Oct 23, 2023	PICKERING GRANT	SALE	46.98	11.24K	527.86K	389.68K
Oct 18, 2023	GUGGENHIME ANDREW	SALE	45.88	7.5K	344K	79.98K
Oct 02, 2023	PICKERING GRANT	SALE	49.67	641	31.84K	155.88K
Oct 02, 2023	EYDELMAN MIKHAIL	SALE	49.58	7.99K	396.24K	32.5K
Oct 02, 2023	WASSIL JIM	SALE	49.69	1.54K	76.62K	172.39K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES30.42K8

NET SHARES-30.42K8

SHARES HELD617.84K8

% NET SHARES-104.92%0%

PCVX Stock Ownership Breakdown

Vaxcyte

Stock Outstanding Shares

Market Insider

Institutional Ownership

Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions

Stock Outstanding Shares

Market Insider

Institutional Ownership

Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions