How many institutions own PASG stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own PASG shares is 45, representing 54.5% of the company's common stock.

Who are the major shareholders selling Passage Bio, Inc. stock?

JPMORGAN CHASE & CO, in the last quarter, reduced its stake in PASG by -100% restricting it's holding to 0 shares of worth nearly -. SBI SECURITIES CO., LTD. also lessened -95.1% of the PASG shares from its portfolio, reducing its holding to 142 shares of worth $1.14K. TWO SIGMA SECURITIES, LLC also shunned PASG shares holding by -100% last quarter which brought its holding to 0 shares worth -.

Investors who are buying PASG stock?

As per its latest 13F filing, CITADEL ADVISORS LLC increased its stake in PASG by 100% in the last quarter. The institutional holder raised its holding to 19.09 thousand shares having worth more than $152.92K. NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO also added 100% more shares of PASG to its portfolio, raising its holding to 2 shares of worth $16.00. HARBOUR INVESTMENTS, INC. also increased its PASG shares holding by 100% which brought its holding to 3 shares worth $24.00.

PASG's major insiders: who are they?

The insider with the most stakes in PASG is OrbiMed Capital GP VII LLC , at the company. Additionally, PASG stock is highly held by 10 percent owner ORBIMED ADVISORS LLC and 10 percent owner Frazier Life Sciences IX, L.P. among others.

Did an insider recently sell PASG stock?

Company executives, directors, and other insiders own 0.21% percent of Passage Bio, Inc.'s stock. Within the last six months, there have been 2 transaction(s) in which PASG insiders have sold stock, totaling 6.14K shares. Insiders that have sold shares include BORTHWICK KATHLEEN, CHOU WILLIAM, and ORBIMED ADVISORS LLC.

Which insider recently purchased PASG stock?

There have been 3 transaction(s) during the past 6-months in which Passage Bio, Inc. insiders have bought stock, totalling 32008 shares

How much of PASG does insiders own?

Around 1.84M Passage Bio, Inc. shares are held by insiders, which represents about 0.21% of PASG stock.

Who is the insider with the largest stake?

PASG , OrbiMed Capital GP VII LLC holds the largest portfolio of the company's shares. PASG shares owned by OrbiMed total nearly 6.54 million.

Which institution holds the most shares in PASG?

JPMORGAN CHASE & CO is the largest institutional owner in PASG which holds 0 shares worth - or 0% of the total PASG shares outstanding followed by SBI SECURITIES CO., LTD. with ownership of 142 shares representing 0% of the PASG ownership. TWO SIGMA SECURITIES, LLC is the third largest stakeholder with 0 shares or 0% of the ownership worth more than -.

Is Passage Bio, Inc. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the PASG is concerned, it is a stock which is not optionable.

Is there a short position on PASG's shares?

Number of PASG shares short is 97.13K. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding PASG shares are there?

As of today, 3.18M shares of PASG are outstanding.

Is there many float in PASG stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, PASG has 2.87M shares in float.

PASG short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for PASG is 1.12.

Passage Bio (PASG) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableNo

Short Percent Of Outstanding Shares3.06

Short Percent Of Float4.12

Shares Outstanding3.18M

Shares Float2.87M

Shares Short97.13K

Short Ratio1.12

4.12%

Short % of Float

3.06%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

0.21% Percentage of Shares held by All Insiders

54.5% Percentage of Shares held by All Institutions

54.62% Percentage of Float held by Institutions

Number of Institutions Holding Shares

Institutional Ownership

About 54.5% of PASG shares are held by financial institutions. JPMORGAN CHASE & CO is the top corporate investor, holding 0 shares valued at -. A 0% stake in Passage Bio, Inc. is owned by the company. SBI SECURITIES CO., LTD. owns 142 shares valued at $1.14K, which translates its holding of 0% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Sep 30, 2025	JPMORGAN CHASE & CO	0%	0	-	-273	-100.00%
Sep 30, 2025	SBI SECURITIES CO., LTD.	0%	142	1.14K	-2.75K	-95.10%
Sep 30, 2025	TWO SIGMA SECURITIES, LLC	0%	0	-	-11.72K	-100.00%
Sep 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0%	0	-	-28K	-100.00%
Sep 30, 2025	CITADEL ADVISORS LLC	0.6%	19.09K	152.92K	19.09K	+100.00%
Sep 30, 2025	MARINER, LLC	0%	0	-	-11.93K	-100.00%
Sep 30, 2025	MILLENNIUM MANAGEMENT LLC	0%	0	-	-10.73K	-100.00%
Sep 30, 2025	FIDUCIARY TRUST CO	0%	0	-	-215K	-100.00%
Sep 30, 2025	TANG CAPITAL MANAGEMENT LLC	0%	0	-	-1.5M	-100.00%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0%	0	-	-538.58K	-100.00%
Sep 30, 2025	TWO SIGMA INVESTMENTS, LP	0%	0	-	-47.16K	-100.00%
Sep 30, 2025	RBF CAPITAL, LLC	0%	0	-	-142.81K	-100.00%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	0%	0	-	-11.59K	-100.00%
Sep 30, 2025	RAYMOND JAMES FINANCIAL INC	0%	0	-	-6.39K	-100.00%
Sep 30, 2025	STATE STREET CORP	0%	0	-	-156.77K	-100.00%
Sep 30, 2025	NORTHERN TRUST CORP	0%	0	-	-112.06K	-100.00%
Sep 30, 2025	NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO	0%	2	16	2	+100.00%
Sep 30, 2025	HARBOUR INVESTMENTS, INC.	0%	3	24	3	+100.00%
Sep 30, 2025	LRI INVESTMENTS, LLC	0%	12	96	-213	-94.67%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0%	0	-	-225	-100.00%
Sep 30, 2025	PARALLEL ADVISORS, LLC	0%	16	128	16	+100.00%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0%	0	-	-503	-100.00%
Sep 30, 2025	CITIGROUP INC	0%	77	617	77	+100.00%
Sep 30, 2025	MAI CAPITAL MANAGEMENT	0.01%	200	1.61K	200	+100.00%
Sep 30, 2025	BARCLAYS PLC	0%	0	-	-4.22K	-100.00%
Sep 30, 2025	SQUAREPOINT OPS LLC	0.74%	23.5K	188.24K	23.5K	+100.00%
Sep 30, 2025	BLACKROCK, INC.	0.94%	29.75K	238.88K	29.75K	+100.00%
Sep 30, 2025	NEW LEAF VENTURE PARTNERS, L.L.C.	2.76%	87.43K	702.03K	-2.41M	-96.50%
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0%	0	-	-1.42M	-100.00%
Sep 30, 2025	VANGUARD GROUP INC	0%	0	-	-2.04M	-100.00%
Sep 30, 2025	ERSTE ASSET MANAGEMENT GMBH	3.87%	122.79K	999.46K	122.79K	+100.00%
Sep 30, 2025	VESTAL POINT CAPITAL, LP	9.62%	305K	2.45M	305K	+100.00%
Sep 30, 2025	GROUP ONE TRADING, L.P.	0%	0	-	-47	-100.00%
Sep 30, 2025	LYNX1 CAPITAL MANAGEMENT LP	19.68%	623.7K	5.01M	623.7K	+100.00%
Sep 30, 2025	XTX TOPCO LTD	0%	0	-	-60.89K	-100.00%
Sep 30, 2025	RITHOLTZ WEALTH MANAGEMENT	0%	0	-	-25.39K	-100.00%
Sep 30, 2025	ADVISOR GROUP HOLDINGS, INC.	0%	20	141	20	+100.00%
Sep 30, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0%	0	-	-416.04K	-100.00%
Sep 30, 2025	MORGAN STANLEY	0%	0	-	-6.53K	-100.00%
Sep 30, 2025	ORBIMED ADVISORS LLC	0%	0	-	-6.06M	-100.00%
Sep 30, 2025	ACADIAN ASSET MANAGEMENT LLC	0%	0	-	-933.76K	-100.00%
Sep 30, 2025	UBS GROUP AG	0%	17	137	17	+100.00%
Sep 30, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0.01%	289	2.32K	289	+100.00%
Sep 30, 2025	SIMPLEX TRADING, LLC	0%	0	-	-82.98K	-100.00%
Jun 30, 2025	TWO SIGMA INVESTMENTS, LP	0.07%	47.16K	18.88K	201	+0.43%
Jun 30, 2025	XTX TOPCO LTD	0.1%	60.89K	24.37K	15.49K	+34.11%
Jun 30, 2025	DLK INVESTMENT MANAGEMENT, LLC	0.1%	61K	24.42K	8K	+15.09%
Jun 30, 2025	SIMPLEX TRADING, LLC	0.13%	82.98K	33K	637	+0.77%
Jun 30, 2025	UBS GROUP AG	0%	3	1	-14.48K	-99.98%
Jun 30, 2025		0%	0	-	-305	-100.00%
Jun 30, 2025	MORGAN STANLEY	0.01%	6.53K	2.61M	-300	-4.39%
Jun 30, 2025	TWO SIGMA SECURITIES, LLC	0.02%	11.72K	4.69K	11.72K	+100.00%
Jun 30, 2025	RITHOLTZ WEALTH MANAGEMENT	0.04%	25.39K	10.16K	25.39K	+100.00%
Jun 30, 2025	VESTAL POINT CAPITAL, LP	9.62%	6.1M	2.44M	0	0
Jun 30, 2025	LYNX1 CAPITAL MANAGEMENT LP	14.61%	9.26M	3.71M	0	0
Jun 30, 2025	NORTHERN TRUST CORP	0.18%	112.06K	44.86K	75	+0.07%
Jun 30, 2025	FIDUCIARY TRUST CO	0.34%	215K	86.07K	0	0
Jun 30, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.66%	416.04K	166.54K	-90.1K	-17.80%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.85%	538.58K	215.63K	-7.52K	-1.38%
Jun 30, 2025	BLACKROCK, INC.	0.94%	594.87K	238.13K	-123.58K	-17.20%
Jun 30, 2025	ACADIAN ASSET MANAGEMENT LLC	1.47%	933.76K	372K	0	0
Jun 30, 2025	RENAISSANCE TECHNOLOGIES LLC	2.23%	1.42M	566.98K	6.12K	+0.43%
Jun 30, 2025	MID-AMERICAN WEALTH ADVISORY GROUP, INC.	0%	32	13	32	+100.00%
Jun 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0%	225	90	39	+20.97%
Jun 30, 2025	JPMORGAN CHASE & CO	0%	273	109	-319	-53.89%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0%	503	201	58	+13.03%
Jun 30, 2025	TANG CAPITAL MANAGEMENT LLC	2.37%	1.5M	600.45K	0	0
Jun 30, 2025	ERSTE ASSET MANAGEMENT GMBH	3.87%	2.46M	979.2K	0	0
Jun 30, 2025	NEW LEAF VENTURE PARTNERS, L.L.C.	3.94%	2.5M	19.98M	0	0
Jun 30, 2025	ORBIMED ADVISORS LLC	9.55%	6.06M	2.42M	-979.33K	-13.92%
Jun 30, 2025	VANGUARD GROUP INC	3.22%	2.04M	816.23K	-30.97K	-1.50%
Jun 30, 2025	ADVISOR GROUP HOLDINGS, INC.	0%	2K	801	0	0
Jun 30, 2025	RAYMOND JAMES FINANCIAL INC	0.01%	6.39K	2.56K	6.39K	+100.00%
Jun 30, 2025	MARINER, LLC	0.02%	11.93K	4.78K	0	0
Jun 30, 2025	RBF CAPITAL, LLC	0.23%	142.81K	57.17K	0	0
Jun 30, 2025	BANQUE TRANSATLANTIQUE SA	0%	0	-	-305	-100.00%
Jun 30, 2025	LRI INVESTMENTS, LLC	0%	0	-	-225	-100.00%
Jun 30, 2025	FARTHER FINANCE ADVISORS, LLC	0%	0	-	-50	-100.00%
Jun 30, 2025	SBI SECURITIES CO., LTD.	0%	0	-	-5.28K	-100.00%
Jun 30, 2025	SHAY CAPITAL LLC	0%	0	-	-146.72K	-100.00%
Jun 30, 2025	SQUAREPOINT OPS LLC	0%	0	-	-64.14K	-100.00%
Jun 30, 2025	STATE STREET CORP	0.25%	156.77K	62.76K	0	0
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.02%	11.59K	4.64M	-5	-0.04%
Jun 30, 2025	CITADEL ADVISORS LLC	0.02%	12.5K	5M	12.5K	+100.00%
Jun 30, 2025	HIGHTOWER ADVISORS, LLC	0%	0	-	-18.35K	-100.00%
Jun 30, 2025	MAI CAPITAL MANAGEMENT	0%	0	-	-4K	-100.00%
Jun 30, 2025	HARBOUR INVESTMENTS, INC.	0%	0	-	-60	-100.00%
Jun 30, 2025	GROUP ONE TRADING, L.P.	0%	47	19	0	0
Jun 30, 2025	BARCLAYS PLC	0.01%	4.22K	2K	0	0
Jun 30, 2025	MILLENNIUM MANAGEMENT LLC	0.02%	10.73K	4.3K	-125.49K	-92.12%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.04%	28K	11.2K	-22.3K	-44.33%
Jun 30, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0.05%	29.28K	11.72K	22.96K	+363.57%
Mar 31, 2025	BARCLAYS PLC	0.01%	4.22K	1K	-8.93K	-67.89%
Mar 31, 2025	RENAISSANCE TECHNOLOGIES LLC	2.27%	1.41M	497.97K	28.8K	+2.08%
Mar 31, 2025	ACADIAN ASSET MANAGEMENT LLC	1.5%	933.76K	328K	-9.14K	-0.97%
Mar 31, 2025	HIGHTOWER ADVISORS, LLC	0.03%	18.35K	6.48K	2.82K	+18.19%
Mar 31, 2025	UBS GROUP AG	0.02%	14.49K	5.11K	14.48K	+724,200.00%
Mar 31, 2025	BLACKROCK, INC.	1.16%	718.45K	253.68K	-3.85K	-0.53%
Mar 31, 2025	JPMORGAN CHASE & CO	0%	592	209	319	+116.85%
Mar 31, 2025	GROUND SWELL CAPITAL, LLC	0%	0	-	-25.42K	-100.00%
Mar 31, 2025	XTX TOPCO LTD	0.07%	45.4K	16.03K	45.4K	+100.00%
Mar 31, 2025	VIRTU FINANCIAL LLC	0%	0	-	-10.29K	-100.00%
Mar 31, 2025	GROUP ONE TRADING, L.P.	0%	47	17	0	0
Mar 31, 2025	LYNX1 CAPITAL MANAGEMENT LP	14.9%	9.26M	3.27M	0	0
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	0.22%	136.22K	48.1K	-12.38K	-8.33%
Mar 31, 2025	SIMPLEX TRADING, LLC	0.13%	82.35K	29K	82.35K	+100.00%
Mar 31, 2025	SQUAREPOINT OPS LLC	0.1%	64.14K	22.65K	42	+0.07%
Mar 31, 2025	DLK INVESTMENT MANAGEMENT, LLC	0.09%	53K	18.71K	0	0
Mar 31, 2025	MORGAN STANLEY	0.01%	6.83K	2.41K	-805.61K	-99.16%
Mar 31, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0.01%	6.32K	2.23K	-48.16K	-88.41%
Mar 31, 2025	MAI CAPITAL MANAGEMENT	0.01%	4K	1.41K	0	0
Mar 31, 2025	ADVISOR GROUP HOLDINGS, INC.	0%	2K	706	230	+12.99%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0%	445	157	23	+5.45%
Mar 31, 2025	LRI INVESTMENTS, LLC	0%	225	79	0	0
Mar 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0%	186	66	0	0
Mar 31, 2025	HARBOUR INVESTMENTS, INC.	0%	60	21	0	0
Mar 31, 2025	FMR LLC	0%	0	-	-21.05K	-100.00%
Mar 31, 2025	HRT FINANCIAL LP	0%	0	-	-13.85K	-100.00%
Mar 31, 2025	MARINER, LLC	0.02%	11.93K	4.21K	11.93K	+100.00%
Mar 31, 2025	JANE STREET GROUP, LLC	0%	0	-	-78.19K	-100.00%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.88%	546.1K	192.87K	14.54K	+2.73%
Mar 31, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.81%	506.14K	178.72K	-50K	-8.99%
Mar 31, 2025	FIDUCIARY TRUST CO	0.35%	215K	75.92K	0	0
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.02%	11.6K	4.1K	-15.47K	-57.16%
Mar 31, 2025	ATRIA WEALTH SOLUTIONS, INC.	0%	0	-	-10K	-100.00%
Mar 31, 2025	STATE STREET CORP	0.25%	156.77K	55.36K	0	0
Mar 31, 2025	SHAY CAPITAL LLC	0.24%	146.72K	51.81K	-78.54K	-34.87%
Mar 31, 2025	RBF CAPITAL, LLC	0.23%	142.81K	50.43K	0	0
Mar 31, 2025	NORTHERN TRUST CORP	0.18%	111.98K	39.54K	49.51K	+79.24%
Mar 31, 2025	TWO SIGMA INVESTMENTS, LP	0.08%	46.96K	16.58K	-2.41K	-4.88%
Mar 31, 2025	ORBIMED ADVISORS LLC	11.33%	7.03M	2.48M	-370.24K	-5.00%
Mar 31, 2025	VESTAL POINT CAPITAL, LP	9.82%	6.1M	2.15M	0	0
Mar 31, 2025		0%	305	100	305	+100.00%
Mar 31, 2025	VANGUARD GROUP INC	3.34%	2.07M	731.25K	0	0
Mar 31, 2025	TANG CAPITAL MANAGEMENT LLC	2.42%	1.5M	529.65K	0	0
Mar 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.08%	50.3K	17.61K	39.8K	+379.05%
Mar 31, 2025	FARTHER FINANCE ADVISORS, LLC	0%	50	19	0	0
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	0.7%	384.28K	518.91K	52.08K	+15.68%
Mar 31, 2024	MARSHALL WACE, LLP	0.04%	21.99K	29.69K	21.99K	+100.00%
Mar 31, 2024	CRESSET ASSET MANAGEMENT, LLC	0.04%	23.73K	32.03K	0	0
Mar 31, 2024	VIRTU FINANCIAL LLC	0.05%	25.43K	34K	-42.28K	-62.45%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.05%	26.95K	36.39K	58	+0.22%
Mar 31, 2024	DLK INVESTMENT MANAGEMENT, LLC	0.12%	64K	86.4K	0	0
Mar 31, 2024	RBF CAPITAL, LLC	0.26%	142.81K	192.79K	0	0
Mar 31, 2024	TWO SIGMA INVESTMENTS, LP	0.37%	201.15K	271.56K	0	0
Mar 31, 2024	TWO SIGMA ADVISERS, LP	0.38%	209.6K	282.96K	-900	-0.43%
Mar 31, 2024	FIDUCIARY TRUST CO	0.39%	215K	290.25K	100K	+86.96%
Mar 31, 2024	AFFINITY ASSET ADVISORS, LLC	0.48%	264.27K	356.76K	264.27K	+100.00%
Mar 31, 2024		0%	10	14	10	+100.00%
Mar 31, 2024	ACUITAS INVESTMENTS, LLC	0.85%	469.31K	633.56K	51.57K	+12.35%
Mar 31, 2024	BRIDGEWAY CAPITAL MANAGEMENT, LLC	1.01%	556.14K	750.79K	49.54K	+9.78%
Mar 31, 2024	MILLENNIUM MANAGEMENT LLC	1.58%	865.74K	1.17M	77.56K	+9.84%
Mar 31, 2024	BLACKROCK INC.	1.68%	922.55K	1.25M	-100.02K	-9.78%
Mar 31, 2024	ACADIAN ASSET MANAGEMENT LLC	1.75%	961.27K	1.3M	356.59K	+58.97%
Mar 31, 2024	RENAISSANCE TECHNOLOGIES LLC	2.19%	1.21M	1.63M	-17.83K	-1.46%
Mar 31, 2024	TANG CAPITAL MANAGEMENT LLC	2.73%	1.5M	2.03M	-900K	-37.50%
Mar 31, 2024	WELLS FARGO & COMPANY/MN	0%	309	417	5	+1.64%
Mar 31, 2024	CITADEL ADVISORS LLC	0%	500	675	400	+400.00%
Mar 31, 2024	ROYAL BANK OF CANADA	0%	500	1K	500	+100.00%
Mar 31, 2024	RHUMBLINE ADVISERS	0%	783	1.06K	0	0
Mar 31, 2024	FEDERATED HERMES, INC.	0%	783	1.06K	783	+100.00%
Mar 31, 2024	CITIGROUP INC	0.01%	3.97K	5.36K	-829	-17.28%
Mar 31, 2024	CUBIST SYSTEMATIC STRATEGIES, LLC	0.02%	11.29K	15.24K	11.29K	+100.00%
Mar 31, 2024	XTX TOPCO LTD	0.08%	42.96K	58K	14.53K	+51.12%
Mar 31, 2024	NORTHERN TRUST CORP	0.15%	84.27K	113.76K	7.38K	+9.60%
Mar 31, 2024	MARQUETTE ASSET MANAGEMENT, LLC	0.16%	85.5K	115.43K	0	0
Mar 31, 2024	STATE STREET CORP	0.23%	123.87K	167.23K	0	0
Mar 31, 2024	PALE FIRE CAPITAL SE	0.26%	141.44K	190.94K	-439.82K	-75.67%
Mar 31, 2024	VESTAL POINT CAPITAL, LP	8.19%	4.5M	6.08M	4.5M	+100.00%
Mar 31, 2024	VERSANT VENTURE MANAGEMENT, LLC	9.03%	4.96M	6.7M	0	0
Mar 31, 2024	UBS GROUP AG	0%	0	-	-1.06K	-100.00%
Mar 31, 2024	SIMPLEX TRADING, LLC	0%	0	-	-2.09K	-100.00%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0%	0	-	-13.65K	-100.00%
Mar 31, 2024	VANGUARD GROUP INC	3.77%	2.07M	2.8M	52.66K	+2.61%
Mar 31, 2024	NEW LEAF VENTURE PARTNERS, L.L.C.	4.55%	2.5M	3.37M	0	0
Mar 31, 2024	LYNX1 CAPITAL MANAGEMENT LP	8.82%	4.85M	6.54M	4.47M	+1,178.06%
Mar 31, 2024	ORBIMED ADVISORS LLC	18.43%	10.12M	13.67M	0	0
Mar 31, 2024	JPMORGAN CHASE & CO	0%	273	369	-1.1K	-80.17%
Mar 31, 2024	LRI INVESTMENTS, LLC	0%	225	304	225	+100.00%
Mar 31, 2024	ADVISOR GROUP HOLDINGS, INC.	0%	217	293	0	0
Mar 31, 2024	GROUP ONE TRADING, L.P.	0%	47	63	0	0
Mar 31, 2024	TOWER RESEARCH CAPITAL LLC (TRC)	0%	34	46	34	+100.00%
Mar 31, 2024	FEDERATION DES CAISSES DESJARDINS DU QUEBEC	0%	10	14	10	+100.00%
Mar 31, 2024	QUBE RESEARCH & TECHNOLOGIES LTD	0%	4	5	0	0
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0%	1	1	-31	-96.88%
Mar 31, 2024	BARCLAYS PLC	0.02%	13.15K	18K	0	0
Mar 31, 2024	MORGAN STANLEY	0.03%	13.84K	18.68K	0	0
Mar 31, 2024	FMR LLC	0.04%	21.07K	28.45K	-40.95K	-66.03%
Mar 31, 2024	HIGHTOWER ADVISORS, LLC	0.04%	21.76K	29K	-501	-2.25%
Dec 31, 2023		0.03%	18.85K	19.04K	18.85K	+100.00%
Dec 31, 2023	HIGHTOWER ADVISORS, LLC	0.04%	22.26K	23K	1.83K	+8.95%
Dec 31, 2023	CRESSET ASSET MANAGEMENT, LLC	0.04%	23.73K	23.96K	0	0
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.05%	26.9K	27.17K	-553	-2.01%
Dec 31, 2023	XTX TOPCO LTD	0.05%	28.43K	28.71K	7.01K	+32.70%
Dec 31, 2023	TWO SIGMA SECURITIES, LLC	0.07%	40.33K	40.73K	40.33K	+100.00%
Dec 31, 2023	FMR LLC	0.11%	62.02K	62.64K	0	0
Dec 31, 2023	VIRTU FINANCIAL LLC	0.12%	67.7K	68K	67.7K	+100.00%
Dec 31, 2023	GROUP ONE TRADING, L.P.	0%	47	47K	0	0
Dec 31, 2023	CITADEL ADVISORS LLC	0%	100	101	100	+100.00%
Dec 31, 2023	NORTHERN TRUST CORP	0.14%	76.89K	77.65K	23.77K	+44.76%
Dec 31, 2023	ADVISOR GROUP HOLDINGS, INC.	0%	217	219	-59	-21.38%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.02%	13.65K	13.78K	0	0
Dec 31, 2023	FEDERATED HERMES, INC.	0%	0	-	-511	-100.00%
Dec 31, 2023	FIDUCIARY TRUST CO	0.21%	115K	116.15K	0	0
Dec 31, 2023	STATE STREET CORP	0.23%	123.87K	125.11K	0	0
Dec 31, 2023	RBF CAPITAL, LLC	0.26%	142.81K	144.24K	0	0
Dec 31, 2023	TWO SIGMA INVESTMENTS, LP	0.37%	201.15K	203.17K	-27.1K	-11.87%
Dec 31, 2023	TWO SIGMA ADVISERS, LP	0.38%	210.5K	212.61K	-29.7K	-12.36%
Dec 31, 2023	WEISS MULTI-STRATEGY ADVISERS LLC	0.44%	242.9K	245K	-124.8K	-33.94%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	0.61%	332.2K	335.62K	0	0
Dec 31, 2023	LYNX1 CAPITAL MANAGEMENT LP	0.69%	379.16K	382.95K	189.04K	+99.43%
Dec 31, 2023	ACUITAS INVESTMENTS, LLC	0.76%	417.73K	421.91K	-427	-0.10%
Dec 31, 2023	MORGAN STANLEY	0.03%	13.84K	13.98K	-163.08K	-92.18%
Dec 31, 2023	WELLS FARGO & COMPANY/MN	0%	304	307	16	+5.56%
Dec 31, 2023	RHUMBLINE ADVISERS	0%	783	790	0	0
Dec 31, 2023	STEWARD PARTNERS INVESTMENT ADVISORY, LLC	0%	1.01K	1.02K	0	0
Dec 31, 2023	UBS GROUP AG	0%	1.06K	1.07K	1.06K	+100.00%
Dec 31, 2023	JPMORGAN CHASE & CO	0%	1.38K	1.39K	-8.01K	-85.33%
Dec 31, 2023	SIMPLEX TRADING, LLC	0%	2.09K	2K	2.09K	+100.00%
Dec 31, 2023	CITIGROUP INC	0.01%	4.8K	4.85K	4.8K	+100.00%
Dec 31, 2023	BARCLAYS PLC	0.02%	13.15K	13K	0	0
Dec 31, 2023	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.92%	506.6K	511.67K	0	0
Dec 31, 2023	PALE FIRE CAPITAL SE	1.06%	581.26K	587.07K	482.6K	+489.14%
Dec 31, 2023	ACADIAN ASSET MANAGEMENT LLC	1.1%	604.68K	610K	0	0
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	1.44%	788.18K	796.06K	671.76K	+577.03%
Dec 31, 2023	BLACKROCK INC.	1.87%	1.02M	1.03M	10.24K	+1.01%
Dec 31, 2023	RENAISSANCE TECHNOLOGIES LLC	2.23%	1.22M	1.24M	228.95K	+23.02%
Dec 31, 2023	VANGUARD GROUP INC	3.68%	2.02M	2.04M	999	+0.05%
Dec 31, 2023	TANG CAPITAL MANAGEMENT LLC	4.38%	2.4M	2.42M	2M	+500.00%
Dec 31, 2023	NEW LEAF VENTURE PARTNERS, L.L.C.	4.56%	2.5M	2.52M	0	0
Dec 31, 2023	VERSANT VENTURE MANAGEMENT, LLC	9.05%	4.96M	5.01M	0	0
Dec 31, 2023	MARQUETTE ASSET MANAGEMENT, LLC	0.16%	85.5K	86.36K	-550	-0.64%
Dec 31, 2023	ORBIMED ADVISORS LLC	18.48%	10.12M	10.23M	0	0
Dec 31, 2023	D. E. SHAW & CO., INC.	0%	0	-	-10.03K	-100.00%
Dec 31, 2023	US BANCORP \DE\	0%	0	-	-500	-100.00%
Dec 31, 2023	QUBE RESEARCH & TECHNOLOGIES LTD	0%	4	4	0	0
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0%	32	32	31	+3,100.00%

Insiders

Among the PASG insiders holding of 0.21% of the stake in company, ORBIMED CAPITAL GP VII LLC, , holds the largest shares of 6.54M. ORBIMED ADVISORS LLC, 10 percent owner, is the second largest PASG insider with ownership of 6.07M shares. FRAZIER LIFE SCIENCES IX, L.P., 10 percent owner, stands third with possession of 5.01M shares of that stake.

Insiders	Designation	Shares Held
ORBIMED CAPITAL GP VII LLC		6.54M
ORBIMED ADVISORS LLC	10 percent owner	6.07M
FRAZIER LIFE SCIENCES IX, L.P.	10 percent owner	5.01M
HERON PATRICK J		5.01M
WOIWODE THOMAS		933.35K
VERSANT VENTURE CAPITAL VI, L.P.	10 percent owner	933.35K
YAMADA TADATAKA	director	656.15K
LYNX1 CAPITAL MANAGEMENT LP	10 percent owner	623.7K
QUIGLEY JILL M.	Chief Operating Officer	295.28K
FORMAN MARK S	CHIEF MEDICAL OFFICER	48.63K
CALE EDGAR B.	GC & Corporate Secretary	46K
FOTOPOULOS ALEXANDROS	Chief Technical Officer	28.69K
KING SIMONA	Chief Financial Officer	23.99K
COUNTOURIOTIS ATHENA	director	18.9K
GOLDSMITH BRUCE A	CEO and President	15.98K
CHOU WILLIAM	PRESIDENT AND CEO	6.52K
MORRIS RICHARD STEVEN	Chief Financial Officer	5.45K
BORTHWICK KATHLEEN	CFO	5.4K
ISLAM SAQIB	director	5K
TOERNSEN MONIKA MARIA	Chief Commercial Officer	3.32K
RATCLIFFE LIAM	director	2.8K
KAPADIA SANDIP	director	0
ROMANO GARY	Chief Medical Officer	0

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Jan 08, 2026	BORTHWICK KATHLEEN	SALE	18.44	2.06K	38.02K	5.4K
Jan 08, 2026	CHOU WILLIAM	SALE	18.44	4.08K	75.16K	6.52K
Sep 15, 2025	LYNX1 CAPITAL MANAGEMENT LP	PURCHASE	6.99	11.9K	83.18K	623.7K
Sep 12, 2025	LYNX1 CAPITAL MANAGEMENT LP	PURCHASE	6.99	19.78K	138.3K	611.8K
Sep 11, 2025	LYNX1 CAPITAL MANAGEMENT LP	PURCHASE	6.96	325	2.26K	592.02K
Jul 24, 2025	LYNX1 CAPITAL MANAGEMENT LP	PURCHASE	5.71	66.42K	379.45K	591.7K
Jul 23, 2025	LYNX1 CAPITAL MANAGEMENT LP	PURCHASE	5.74	49.3K	283.03K	525.27K
Jul 22, 2025	LYNX1 CAPITAL MANAGEMENT LP	PURCHASE	5.44	13.12K	71.34K	475.97K
Jun 26, 2025	ORBIMED ADVISORS LLC	SALE	0.33	213.26K	70.37K	6.07M
Jun 25, 2025	ORBIMED ADVISORS LLC	SALE	0.33	138.8K	45.8K	6.28M
Jun 24, 2025	ORBIMED ADVISORS LLC	SALE	0.35	231.6K	81.06K	6.42M
Apr 24, 2025	ORBIMED ADVISORS LLC	SALE	0.32	68.2K	21.82K	6.65M
Apr 23, 2025	ORBIMED ADVISORS LLC	SALE	0.34	89.33K	30.37K	6.72M
Apr 22, 2025	ORBIMED ADVISORS LLC	SALE	0.34	78.05K	26.54K	6.81M
Apr 17, 2025	ORBIMED ADVISORS LLC	SALE	0.33	77.09K	25.44K	6.89M
Apr 16, 2025	ORBIMED ADVISORS LLC	SALE	0.33	61.64K	20.34K	6.96M
Apr 15, 2025	ORBIMED ADVISORS LLC	SALE	0.38	10.33K	3.92K	7.02M
Feb 11, 2025	BORTHWICK KATHLEEN	SALE	0.53	3.18K	1.69K	41.28K
Jan 14, 2025	ORBIMED ADVISORS LLC	SALE	0.60	79.02K	47.41K	7.03M
Jan 13, 2025	ORBIMED ADVISORS LLC	SALE	0.64	17.99K	11.51K	7.11M
Jan 10, 2025	ORBIMED ADVISORS LLC	SALE	0.66	126.21K	83.3K	7.13M
Jan 08, 2025	ORBIMED ADVISORS LLC	SALE	0.68	75.01K	51K	7.26M
Jan 07, 2025	ORBIMED ADVISORS LLC	SALE	0.71	52.54K	37.3K	7.33M
Jan 06, 2025	ORBIMED ADVISORS LLC	SALE	0.77	19.48K	15K	7.39M
Dec 27, 2024	LYNX1 CAPITAL MANAGEMENT LP	PURCHASE	0.65	373.65K	241.04K	9.26M
Dec 20, 2024	ORBIMED ADVISORS LLC	SALE	0.60	230.32K	138.19K	7.4M
Dec 11, 2024	ORBIMED ADVISORS LLC	SALE	0.80	80	64	7.64M
Dec 10, 2024	ORBIMED ADVISORS LLC	SALE	0.80	8.02K	6.41K	7.64M
Dec 09, 2024	ORBIMED ADVISORS LLC	SALE	0.84	54.18K	45.51K	7.64M
Dec 06, 2024	ORBIMED ADVISORS LLC	SALE	0.82	20.9K	17.14K	7.7M
Dec 04, 2024	ORBIMED ADVISORS LLC	SALE	0.79	76.2K	60.2K	7.72M
Nov 27, 2024	LYNX1 CAPITAL MANAGEMENT LP	PURCHASE	0.67	29.3K	19.66K	8.88M
Nov 26, 2024	LYNX1 CAPITAL MANAGEMENT LP	PURCHASE	0.71	167.06K	118.19K	8.85M
Nov 25, 2024	LYNX1 CAPITAL MANAGEMENT LP	PURCHASE	0.56	260K	146.66K	8.69M
Sep 19, 2024	ORBIMED ADVISORS LLC	SALE	0.71	39.3K	27.9K	7.79M
Sep 18, 2024	ORBIMED ADVISORS LLC	SALE	0.73	25.63K	18.71K	7.83M
Sep 17, 2024	ORBIMED ADVISORS LLC	SALE	0.73	111.4K	81.32K	7.86M
Sep 16, 2024	ORBIMED ADVISORS LLC	SALE	0.74	63.1K	46.69K	7.97M
Feb 13, 2024	FORMAN MARK S	SALE	0.97	1.64K	1.59K	48.63K
Feb 13, 2024	BORTHWICK KATHLEEN	SALE	0.97	1.47K	1.43K	28.47K
Jan 02, 2024	CALE EDGAR B.	SALE	0.91	15.81K	14.39K	46K
Jan 02, 2024	BORTHWICK KATHLEEN	SALE	0.91	10.67K	9.71K	25.94K
Jan 02, 2024	FORMAN MARK S	SALE	0.91	15.81K	14.39K	45.27K
Jul 28, 2023	KING SIMONA	SALE	0.88	11.45K	10.08K	23.99K
Jun 28, 2023	ORBIMED ADVISORS LLC	PURCHASE	0.84	575.2K	483.16K	8.03M
Jun 27, 2023	ORBIMED ADVISORS LLC	PURCHASE	0.84	617.38K	518.6K	7.46M
Jun 16, 2023	FOTOPOULOS ALEXANDROS	SALE	0.93	4.05K	3.78K	28.69K
Apr 18, 2023	KING SIMONA	SALE	1.05	2.05K	2.16K	2.05K
Dec 01, 2022	KAPADIA SANDIP	SALE	1.19	5K	5.96K	0
Nov 22, 2022	FOTOPOULOS ALEXANDROS	SALE	1.33	3.72K	4.95K	20.25K
Sep 19, 2022	TOERNSEN MONIKA MARIA	SALE	1.51	1.68K	2.54K	3.32K
May 04, 2022	ORBIMED ADVISORS LLC	PURCHASE	1.94	303.5K	588.79K	6.84M
May 03, 2022	ORBIMED ADVISORS LLC	PURCHASE	1.93	221.5K	427.5K	6.54M
May 03, 2022	ORBIMED CAPITAL GP VII LLC	PURCHASE	1.93	221.5K	427.5K	6.54M
Mar 21, 2022	GOLDSMITH BRUCE A	PURCHASE	3.15	10K	31.5K	15.98K
Jan 20, 2022	ORBIMED ADVISORS LLC	PURCHASE	5.42	369.1K	2M	6.63M
Jan 19, 2022	ORBIMED ADVISORS LLC	PURCHASE	5.11	43.3K	221.26K	6.27M
Jan 18, 2022	ORBIMED ADVISORS LLC	PURCHASE	5.46	114.7K	626.26K	6.22M
Jan 14, 2022	ORBIMED ADVISORS LLC	PURCHASE	5.60	10.3K	57.68K	6.11M
Jan 13, 2022	ORBIMED ADVISORS LLC	PURCHASE	5.52	41.8K	230.74K	6.1M
Jan 12, 2022	ORBIMED ADVISORS LLC	PURCHASE	5.65	100K	565K	6.06M
Jan 11, 2022	ORBIMED ADVISORS LLC	PURCHASE	5.53	8.2K	45.35K	5.96M
May 21, 2021	GOLDSMITH BRUCE A	PURCHASE	13.12	2K	26.23K	5.98K
May 21, 2021	MORRIS RICHARD STEVEN	PURCHASE	13.82	2.17K	30K	5.45K
Mar 15, 2021	ROMANO GARY	SALE	21.86	1.62K	35.35K	0
Jan 20, 2021	QUIGLEY JILL M.	SALE	30.01	1.3K	39.01K	295.28K
Jan 14, 2021	QUIGLEY JILL M.	SALE	30.10	16.3K	490.57K	296.58K
Mar 24, 2020	COUNTOURIOTIS ATHENA	PURCHASE	14.97	10K	149.75K	18.9K
Mar 03, 2020	QUIGLEY JILL M.	PURCHASE	18.00	1K	18K	1K
Mar 03, 2020	YAMADA TADATAKA	PURCHASE	18.00	6.5K	117K	656.15K
Mar 03, 2020	HERON PATRICK J	PURCHASE	18.00	550K	9.9M	5.01M
Mar 03, 2020	WOIWODE THOMAS	PURCHASE	18.00	225K	4.05M	933.35K
Mar 03, 2020	RATCLIFFE LIAM	PURCHASE	18.00	2.8K	50.4K	2.8K
Mar 03, 2020	VERSANT VENTURE CAPITAL VI, L.P.	PURCHASE	18.00	225K	4.05M	933.35K
Mar 03, 2020	MORRIS RICHARD STEVEN	PURCHASE	18.00	400	7.2K	400
Mar 03, 2020	KAPADIA SANDIP	PURCHASE	18.00	5K	90K	5K
Mar 03, 2020	ISLAM SAQIB	PURCHASE	18.00	5K	90K	5K
Mar 03, 2020	GOLDSMITH BRUCE A	PURCHASE	18.00	1.1K	19.8K	1.1K
Mar 03, 2020	FOTOPOULOS ALEXANDROS	PURCHASE	18.00	5.5K	99K	5.5K
Mar 03, 2020	COUNTOURIOTIS ATHENA	PURCHASE	18.00	8.9K	160.2K	8.9K
Mar 03, 2020	CALE EDGAR B.	PURCHASE	18.00	2K	36K	2K
Mar 03, 2020	FRAZIER LIFE SCIENCES IX, L.P.	PURCHASE	18.00	550K	9.9M	5.01M
Feb 28, 2020	ORBIMED ADVISORS LLC	PURCHASE	18.00	373.3K	6.72M	373.3K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE32.01K3

SALES6.14K2

NET SHARES25.87K1

SHARES HELD1.84M5

% NET SHARES-98.59%-80%

Frequently Asked Questions

Stock Outstanding Shares

ShortableYes

OptionableNo

Short Percent Of Outstanding Shares3.06

Short Percent Of Float4.12

Shares Outstanding3.18M

Shares Float2.87M

Shares Short97.13K

Short Ratio1.12

4.12%

Short % of Float

3.06%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

0.21% Percentage of Shares held by All Insiders

54.5% Percentage of Shares held by All Institutions

54.62% Percentage of Float held by Institutions

Number of Institutions Holding Shares

Institutional Ownership

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Sep 30, 2025	JPMORGAN CHASE & CO	0%	0	-	-273	-100.00%
Sep 30, 2025	SBI SECURITIES CO., LTD.	0%	142	1.14K	-2.75K	-95.10%
Sep 30, 2025	TWO SIGMA SECURITIES, LLC	0%	0	-	-11.72K	-100.00%
Sep 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0%	0	-	-28K	-100.00%
Sep 30, 2025	CITADEL ADVISORS LLC	0.6%	19.09K	152.92K	19.09K	+100.00%
Sep 30, 2025	MARINER, LLC	0%	0	-	-11.93K	-100.00%
Sep 30, 2025	MILLENNIUM MANAGEMENT LLC	0%	0	-	-10.73K	-100.00%
Sep 30, 2025	FIDUCIARY TRUST CO	0%	0	-	-215K	-100.00%
Sep 30, 2025	TANG CAPITAL MANAGEMENT LLC	0%	0	-	-1.5M	-100.00%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0%	0	-	-538.58K	-100.00%
Sep 30, 2025	TWO SIGMA INVESTMENTS, LP	0%	0	-	-47.16K	-100.00%
Sep 30, 2025	RBF CAPITAL, LLC	0%	0	-	-142.81K	-100.00%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	0%	0	-	-11.59K	-100.00%
Sep 30, 2025	RAYMOND JAMES FINANCIAL INC	0%	0	-	-6.39K	-100.00%
Sep 30, 2025	STATE STREET CORP	0%	0	-	-156.77K	-100.00%
Sep 30, 2025	NORTHERN TRUST CORP	0%	0	-	-112.06K	-100.00%
Sep 30, 2025	NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO	0%	2	16	2	+100.00%
Sep 30, 2025	HARBOUR INVESTMENTS, INC.	0%	3	24	3	+100.00%
Sep 30, 2025	LRI INVESTMENTS, LLC	0%	12	96	-213	-94.67%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0%	0	-	-225	-100.00%
Sep 30, 2025	PARALLEL ADVISORS, LLC	0%	16	128	16	+100.00%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0%	0	-	-503	-100.00%
Sep 30, 2025	CITIGROUP INC	0%	77	617	77	+100.00%
Sep 30, 2025	MAI CAPITAL MANAGEMENT	0.01%	200	1.61K	200	+100.00%
Sep 30, 2025	BARCLAYS PLC	0%	0	-	-4.22K	-100.00%
Sep 30, 2025	SQUAREPOINT OPS LLC	0.74%	23.5K	188.24K	23.5K	+100.00%
Sep 30, 2025	BLACKROCK, INC.	0.94%	29.75K	238.88K	29.75K	+100.00%
Sep 30, 2025	NEW LEAF VENTURE PARTNERS, L.L.C.	2.76%	87.43K	702.03K	-2.41M	-96.50%
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0%	0	-	-1.42M	-100.00%
Sep 30, 2025	VANGUARD GROUP INC	0%	0	-	-2.04M	-100.00%
Sep 30, 2025	ERSTE ASSET MANAGEMENT GMBH	3.87%	122.79K	999.46K	122.79K	+100.00%
Sep 30, 2025	VESTAL POINT CAPITAL, LP	9.62%	305K	2.45M	305K	+100.00%
Sep 30, 2025	GROUP ONE TRADING, L.P.	0%	0	-	-47	-100.00%
Sep 30, 2025	LYNX1 CAPITAL MANAGEMENT LP	19.68%	623.7K	5.01M	623.7K	+100.00%
Sep 30, 2025	XTX TOPCO LTD	0%	0	-	-60.89K	-100.00%
Sep 30, 2025	RITHOLTZ WEALTH MANAGEMENT	0%	0	-	-25.39K	-100.00%
Sep 30, 2025	ADVISOR GROUP HOLDINGS, INC.	0%	20	141	20	+100.00%
Sep 30, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0%	0	-	-416.04K	-100.00%
Sep 30, 2025	MORGAN STANLEY	0%	0	-	-6.53K	-100.00%
Sep 30, 2025	ORBIMED ADVISORS LLC	0%	0	-	-6.06M	-100.00%
Sep 30, 2025	ACADIAN ASSET MANAGEMENT LLC	0%	0	-	-933.76K	-100.00%
Sep 30, 2025	UBS GROUP AG	0%	17	137	17	+100.00%
Sep 30, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0.01%	289	2.32K	289	+100.00%
Sep 30, 2025	SIMPLEX TRADING, LLC	0%	0	-	-82.98K	-100.00%
Jun 30, 2025	TWO SIGMA INVESTMENTS, LP	0.07%	47.16K	18.88K	201	+0.43%
Jun 30, 2025	XTX TOPCO LTD	0.1%	60.89K	24.37K	15.49K	+34.11%
Jun 30, 2025	DLK INVESTMENT MANAGEMENT, LLC	0.1%	61K	24.42K	8K	+15.09%
Jun 30, 2025	SIMPLEX TRADING, LLC	0.13%	82.98K	33K	637	+0.77%
Jun 30, 2025	UBS GROUP AG	0%	3	1	-14.48K	-99.98%
Jun 30, 2025		0%	0	-	-305	-100.00%
Jun 30, 2025	MORGAN STANLEY	0.01%	6.53K	2.61M	-300	-4.39%
Jun 30, 2025	TWO SIGMA SECURITIES, LLC	0.02%	11.72K	4.69K	11.72K	+100.00%
Jun 30, 2025	RITHOLTZ WEALTH MANAGEMENT	0.04%	25.39K	10.16K	25.39K	+100.00%
Jun 30, 2025	VESTAL POINT CAPITAL, LP	9.62%	6.1M	2.44M	0	0
Jun 30, 2025	LYNX1 CAPITAL MANAGEMENT LP	14.61%	9.26M	3.71M	0	0
Jun 30, 2025	NORTHERN TRUST CORP	0.18%	112.06K	44.86K	75	+0.07%
Jun 30, 2025	FIDUCIARY TRUST CO	0.34%	215K	86.07K	0	0
Jun 30, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.66%	416.04K	166.54K	-90.1K	-17.80%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.85%	538.58K	215.63K	-7.52K	-1.38%
Jun 30, 2025	BLACKROCK, INC.	0.94%	594.87K	238.13K	-123.58K	-17.20%
Jun 30, 2025	ACADIAN ASSET MANAGEMENT LLC	1.47%	933.76K	372K	0	0
Jun 30, 2025	RENAISSANCE TECHNOLOGIES LLC	2.23%	1.42M	566.98K	6.12K	+0.43%
Jun 30, 2025	MID-AMERICAN WEALTH ADVISORY GROUP, INC.	0%	32	13	32	+100.00%
Jun 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0%	225	90	39	+20.97%
Jun 30, 2025	JPMORGAN CHASE & CO	0%	273	109	-319	-53.89%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0%	503	201	58	+13.03%
Jun 30, 2025	TANG CAPITAL MANAGEMENT LLC	2.37%	1.5M	600.45K	0	0
Jun 30, 2025	ERSTE ASSET MANAGEMENT GMBH	3.87%	2.46M	979.2K	0	0
Jun 30, 2025	NEW LEAF VENTURE PARTNERS, L.L.C.	3.94%	2.5M	19.98M	0	0
Jun 30, 2025	ORBIMED ADVISORS LLC	9.55%	6.06M	2.42M	-979.33K	-13.92%
Jun 30, 2025	VANGUARD GROUP INC	3.22%	2.04M	816.23K	-30.97K	-1.50%
Jun 30, 2025	ADVISOR GROUP HOLDINGS, INC.	0%	2K	801	0	0
Jun 30, 2025	RAYMOND JAMES FINANCIAL INC	0.01%	6.39K	2.56K	6.39K	+100.00%
Jun 30, 2025	MARINER, LLC	0.02%	11.93K	4.78K	0	0
Jun 30, 2025	RBF CAPITAL, LLC	0.23%	142.81K	57.17K	0	0
Jun 30, 2025	BANQUE TRANSATLANTIQUE SA	0%	0	-	-305	-100.00%
Jun 30, 2025	LRI INVESTMENTS, LLC	0%	0	-	-225	-100.00%
Jun 30, 2025	FARTHER FINANCE ADVISORS, LLC	0%	0	-	-50	-100.00%
Jun 30, 2025	SBI SECURITIES CO., LTD.	0%	0	-	-5.28K	-100.00%
Jun 30, 2025	SHAY CAPITAL LLC	0%	0	-	-146.72K	-100.00%
Jun 30, 2025	SQUAREPOINT OPS LLC	0%	0	-	-64.14K	-100.00%
Jun 30, 2025	STATE STREET CORP	0.25%	156.77K	62.76K	0	0
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.02%	11.59K	4.64M	-5	-0.04%
Jun 30, 2025	CITADEL ADVISORS LLC	0.02%	12.5K	5M	12.5K	+100.00%
Jun 30, 2025	HIGHTOWER ADVISORS, LLC	0%	0	-	-18.35K	-100.00%
Jun 30, 2025	MAI CAPITAL MANAGEMENT	0%	0	-	-4K	-100.00%
Jun 30, 2025	HARBOUR INVESTMENTS, INC.	0%	0	-	-60	-100.00%
Jun 30, 2025	GROUP ONE TRADING, L.P.	0%	47	19	0	0
Jun 30, 2025	BARCLAYS PLC	0.01%	4.22K	2K	0	0
Jun 30, 2025	MILLENNIUM MANAGEMENT LLC	0.02%	10.73K	4.3K	-125.49K	-92.12%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.04%	28K	11.2K	-22.3K	-44.33%
Jun 30, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0.05%	29.28K	11.72K	22.96K	+363.57%
Mar 31, 2025	BARCLAYS PLC	0.01%	4.22K	1K	-8.93K	-67.89%
Mar 31, 2025	RENAISSANCE TECHNOLOGIES LLC	2.27%	1.41M	497.97K	28.8K	+2.08%
Mar 31, 2025	ACADIAN ASSET MANAGEMENT LLC	1.5%	933.76K	328K	-9.14K	-0.97%
Mar 31, 2025	HIGHTOWER ADVISORS, LLC	0.03%	18.35K	6.48K	2.82K	+18.19%
Mar 31, 2025	UBS GROUP AG	0.02%	14.49K	5.11K	14.48K	+724,200.00%
Mar 31, 2025	BLACKROCK, INC.	1.16%	718.45K	253.68K	-3.85K	-0.53%
Mar 31, 2025	JPMORGAN CHASE & CO	0%	592	209	319	+116.85%
Mar 31, 2025	GROUND SWELL CAPITAL, LLC	0%	0	-	-25.42K	-100.00%
Mar 31, 2025	XTX TOPCO LTD	0.07%	45.4K	16.03K	45.4K	+100.00%
Mar 31, 2025	VIRTU FINANCIAL LLC	0%	0	-	-10.29K	-100.00%
Mar 31, 2025	GROUP ONE TRADING, L.P.	0%	47	17	0	0
Mar 31, 2025	LYNX1 CAPITAL MANAGEMENT LP	14.9%	9.26M	3.27M	0	0
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	0.22%	136.22K	48.1K	-12.38K	-8.33%
Mar 31, 2025	SIMPLEX TRADING, LLC	0.13%	82.35K	29K	82.35K	+100.00%
Mar 31, 2025	SQUAREPOINT OPS LLC	0.1%	64.14K	22.65K	42	+0.07%
Mar 31, 2025	DLK INVESTMENT MANAGEMENT, LLC	0.09%	53K	18.71K	0	0
Mar 31, 2025	MORGAN STANLEY	0.01%	6.83K	2.41K	-805.61K	-99.16%
Mar 31, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0.01%	6.32K	2.23K	-48.16K	-88.41%
Mar 31, 2025	MAI CAPITAL MANAGEMENT	0.01%	4K	1.41K	0	0
Mar 31, 2025	ADVISOR GROUP HOLDINGS, INC.	0%	2K	706	230	+12.99%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0%	445	157	23	+5.45%
Mar 31, 2025	LRI INVESTMENTS, LLC	0%	225	79	0	0
Mar 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0%	186	66	0	0
Mar 31, 2025	HARBOUR INVESTMENTS, INC.	0%	60	21	0	0
Mar 31, 2025	FMR LLC	0%	0	-	-21.05K	-100.00%
Mar 31, 2025	HRT FINANCIAL LP	0%	0	-	-13.85K	-100.00%
Mar 31, 2025	MARINER, LLC	0.02%	11.93K	4.21K	11.93K	+100.00%
Mar 31, 2025	JANE STREET GROUP, LLC	0%	0	-	-78.19K	-100.00%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.88%	546.1K	192.87K	14.54K	+2.73%
Mar 31, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.81%	506.14K	178.72K	-50K	-8.99%
Mar 31, 2025	FIDUCIARY TRUST CO	0.35%	215K	75.92K	0	0
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.02%	11.6K	4.1K	-15.47K	-57.16%
Mar 31, 2025	ATRIA WEALTH SOLUTIONS, INC.	0%	0	-	-10K	-100.00%
Mar 31, 2025	STATE STREET CORP	0.25%	156.77K	55.36K	0	0
Mar 31, 2025	SHAY CAPITAL LLC	0.24%	146.72K	51.81K	-78.54K	-34.87%
Mar 31, 2025	RBF CAPITAL, LLC	0.23%	142.81K	50.43K	0	0
Mar 31, 2025	NORTHERN TRUST CORP	0.18%	111.98K	39.54K	49.51K	+79.24%
Mar 31, 2025	TWO SIGMA INVESTMENTS, LP	0.08%	46.96K	16.58K	-2.41K	-4.88%
Mar 31, 2025	ORBIMED ADVISORS LLC	11.33%	7.03M	2.48M	-370.24K	-5.00%
Mar 31, 2025	VESTAL POINT CAPITAL, LP	9.82%	6.1M	2.15M	0	0
Mar 31, 2025		0%	305	100	305	+100.00%
Mar 31, 2025	VANGUARD GROUP INC	3.34%	2.07M	731.25K	0	0
Mar 31, 2025	TANG CAPITAL MANAGEMENT LLC	2.42%	1.5M	529.65K	0	0
Mar 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.08%	50.3K	17.61K	39.8K	+379.05%
Mar 31, 2025	FARTHER FINANCE ADVISORS, LLC	0%	50	19	0	0
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	0.7%	384.28K	518.91K	52.08K	+15.68%
Mar 31, 2024	MARSHALL WACE, LLP	0.04%	21.99K	29.69K	21.99K	+100.00%
Mar 31, 2024	CRESSET ASSET MANAGEMENT, LLC	0.04%	23.73K	32.03K	0	0
Mar 31, 2024	VIRTU FINANCIAL LLC	0.05%	25.43K	34K	-42.28K	-62.45%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.05%	26.95K	36.39K	58	+0.22%
Mar 31, 2024	DLK INVESTMENT MANAGEMENT, LLC	0.12%	64K	86.4K	0	0
Mar 31, 2024	RBF CAPITAL, LLC	0.26%	142.81K	192.79K	0	0
Mar 31, 2024	TWO SIGMA INVESTMENTS, LP	0.37%	201.15K	271.56K	0	0
Mar 31, 2024	TWO SIGMA ADVISERS, LP	0.38%	209.6K	282.96K	-900	-0.43%
Mar 31, 2024	FIDUCIARY TRUST CO	0.39%	215K	290.25K	100K	+86.96%
Mar 31, 2024	AFFINITY ASSET ADVISORS, LLC	0.48%	264.27K	356.76K	264.27K	+100.00%
Mar 31, 2024		0%	10	14	10	+100.00%
Mar 31, 2024	ACUITAS INVESTMENTS, LLC	0.85%	469.31K	633.56K	51.57K	+12.35%
Mar 31, 2024	BRIDGEWAY CAPITAL MANAGEMENT, LLC	1.01%	556.14K	750.79K	49.54K	+9.78%
Mar 31, 2024	MILLENNIUM MANAGEMENT LLC	1.58%	865.74K	1.17M	77.56K	+9.84%
Mar 31, 2024	BLACKROCK INC.	1.68%	922.55K	1.25M	-100.02K	-9.78%
Mar 31, 2024	ACADIAN ASSET MANAGEMENT LLC	1.75%	961.27K	1.3M	356.59K	+58.97%
Mar 31, 2024	RENAISSANCE TECHNOLOGIES LLC	2.19%	1.21M	1.63M	-17.83K	-1.46%
Mar 31, 2024	TANG CAPITAL MANAGEMENT LLC	2.73%	1.5M	2.03M	-900K	-37.50%
Mar 31, 2024	WELLS FARGO & COMPANY/MN	0%	309	417	5	+1.64%
Mar 31, 2024	CITADEL ADVISORS LLC	0%	500	675	400	+400.00%
Mar 31, 2024	ROYAL BANK OF CANADA	0%	500	1K	500	+100.00%
Mar 31, 2024	RHUMBLINE ADVISERS	0%	783	1.06K	0	0
Mar 31, 2024	FEDERATED HERMES, INC.	0%	783	1.06K	783	+100.00%
Mar 31, 2024	CITIGROUP INC	0.01%	3.97K	5.36K	-829	-17.28%
Mar 31, 2024	CUBIST SYSTEMATIC STRATEGIES, LLC	0.02%	11.29K	15.24K	11.29K	+100.00%
Mar 31, 2024	XTX TOPCO LTD	0.08%	42.96K	58K	14.53K	+51.12%
Mar 31, 2024	NORTHERN TRUST CORP	0.15%	84.27K	113.76K	7.38K	+9.60%
Mar 31, 2024	MARQUETTE ASSET MANAGEMENT, LLC	0.16%	85.5K	115.43K	0	0
Mar 31, 2024	STATE STREET CORP	0.23%	123.87K	167.23K	0	0
Mar 31, 2024	PALE FIRE CAPITAL SE	0.26%	141.44K	190.94K	-439.82K	-75.67%
Mar 31, 2024	VESTAL POINT CAPITAL, LP	8.19%	4.5M	6.08M	4.5M	+100.00%
Mar 31, 2024	VERSANT VENTURE MANAGEMENT, LLC	9.03%	4.96M	6.7M	0	0
Mar 31, 2024	UBS GROUP AG	0%	0	-	-1.06K	-100.00%
Mar 31, 2024	SIMPLEX TRADING, LLC	0%	0	-	-2.09K	-100.00%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0%	0	-	-13.65K	-100.00%
Mar 31, 2024	VANGUARD GROUP INC	3.77%	2.07M	2.8M	52.66K	+2.61%
Mar 31, 2024	NEW LEAF VENTURE PARTNERS, L.L.C.	4.55%	2.5M	3.37M	0	0
Mar 31, 2024	LYNX1 CAPITAL MANAGEMENT LP	8.82%	4.85M	6.54M	4.47M	+1,178.06%
Mar 31, 2024	ORBIMED ADVISORS LLC	18.43%	10.12M	13.67M	0	0
Mar 31, 2024	JPMORGAN CHASE & CO	0%	273	369	-1.1K	-80.17%
Mar 31, 2024	LRI INVESTMENTS, LLC	0%	225	304	225	+100.00%
Mar 31, 2024	ADVISOR GROUP HOLDINGS, INC.	0%	217	293	0	0
Mar 31, 2024	GROUP ONE TRADING, L.P.	0%	47	63	0	0
Mar 31, 2024	TOWER RESEARCH CAPITAL LLC (TRC)	0%	34	46	34	+100.00%
Mar 31, 2024	FEDERATION DES CAISSES DESJARDINS DU QUEBEC	0%	10	14	10	+100.00%
Mar 31, 2024	QUBE RESEARCH & TECHNOLOGIES LTD	0%	4	5	0	0
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0%	1	1	-31	-96.88%
Mar 31, 2024	BARCLAYS PLC	0.02%	13.15K	18K	0	0
Mar 31, 2024	MORGAN STANLEY	0.03%	13.84K	18.68K	0	0
Mar 31, 2024	FMR LLC	0.04%	21.07K	28.45K	-40.95K	-66.03%
Mar 31, 2024	HIGHTOWER ADVISORS, LLC	0.04%	21.76K	29K	-501	-2.25%
Dec 31, 2023		0.03%	18.85K	19.04K	18.85K	+100.00%
Dec 31, 2023	HIGHTOWER ADVISORS, LLC	0.04%	22.26K	23K	1.83K	+8.95%
Dec 31, 2023	CRESSET ASSET MANAGEMENT, LLC	0.04%	23.73K	23.96K	0	0
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.05%	26.9K	27.17K	-553	-2.01%
Dec 31, 2023	XTX TOPCO LTD	0.05%	28.43K	28.71K	7.01K	+32.70%
Dec 31, 2023	TWO SIGMA SECURITIES, LLC	0.07%	40.33K	40.73K	40.33K	+100.00%
Dec 31, 2023	FMR LLC	0.11%	62.02K	62.64K	0	0
Dec 31, 2023	VIRTU FINANCIAL LLC	0.12%	67.7K	68K	67.7K	+100.00%
Dec 31, 2023	GROUP ONE TRADING, L.P.	0%	47	47K	0	0
Dec 31, 2023	CITADEL ADVISORS LLC	0%	100	101	100	+100.00%
Dec 31, 2023	NORTHERN TRUST CORP	0.14%	76.89K	77.65K	23.77K	+44.76%
Dec 31, 2023	ADVISOR GROUP HOLDINGS, INC.	0%	217	219	-59	-21.38%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.02%	13.65K	13.78K	0	0
Dec 31, 2023	FEDERATED HERMES, INC.	0%	0	-	-511	-100.00%
Dec 31, 2023	FIDUCIARY TRUST CO	0.21%	115K	116.15K	0	0
Dec 31, 2023	STATE STREET CORP	0.23%	123.87K	125.11K	0	0
Dec 31, 2023	RBF CAPITAL, LLC	0.26%	142.81K	144.24K	0	0
Dec 31, 2023	TWO SIGMA INVESTMENTS, LP	0.37%	201.15K	203.17K	-27.1K	-11.87%
Dec 31, 2023	TWO SIGMA ADVISERS, LP	0.38%	210.5K	212.61K	-29.7K	-12.36%
Dec 31, 2023	WEISS MULTI-STRATEGY ADVISERS LLC	0.44%	242.9K	245K	-124.8K	-33.94%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	0.61%	332.2K	335.62K	0	0
Dec 31, 2023	LYNX1 CAPITAL MANAGEMENT LP	0.69%	379.16K	382.95K	189.04K	+99.43%
Dec 31, 2023	ACUITAS INVESTMENTS, LLC	0.76%	417.73K	421.91K	-427	-0.10%
Dec 31, 2023	MORGAN STANLEY	0.03%	13.84K	13.98K	-163.08K	-92.18%
Dec 31, 2023	WELLS FARGO & COMPANY/MN	0%	304	307	16	+5.56%
Dec 31, 2023	RHUMBLINE ADVISERS	0%	783	790	0	0
Dec 31, 2023	STEWARD PARTNERS INVESTMENT ADVISORY, LLC	0%	1.01K	1.02K	0	0
Dec 31, 2023	UBS GROUP AG	0%	1.06K	1.07K	1.06K	+100.00%
Dec 31, 2023	JPMORGAN CHASE & CO	0%	1.38K	1.39K	-8.01K	-85.33%
Dec 31, 2023	SIMPLEX TRADING, LLC	0%	2.09K	2K	2.09K	+100.00%
Dec 31, 2023	CITIGROUP INC	0.01%	4.8K	4.85K	4.8K	+100.00%
Dec 31, 2023	BARCLAYS PLC	0.02%	13.15K	13K	0	0
Dec 31, 2023	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.92%	506.6K	511.67K	0	0
Dec 31, 2023	PALE FIRE CAPITAL SE	1.06%	581.26K	587.07K	482.6K	+489.14%
Dec 31, 2023	ACADIAN ASSET MANAGEMENT LLC	1.1%	604.68K	610K	0	0
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	1.44%	788.18K	796.06K	671.76K	+577.03%
Dec 31, 2023	BLACKROCK INC.	1.87%	1.02M	1.03M	10.24K	+1.01%
Dec 31, 2023	RENAISSANCE TECHNOLOGIES LLC	2.23%	1.22M	1.24M	228.95K	+23.02%
Dec 31, 2023	VANGUARD GROUP INC	3.68%	2.02M	2.04M	999	+0.05%
Dec 31, 2023	TANG CAPITAL MANAGEMENT LLC	4.38%	2.4M	2.42M	2M	+500.00%
Dec 31, 2023	NEW LEAF VENTURE PARTNERS, L.L.C.	4.56%	2.5M	2.52M	0	0
Dec 31, 2023	VERSANT VENTURE MANAGEMENT, LLC	9.05%	4.96M	5.01M	0	0
Dec 31, 2023	MARQUETTE ASSET MANAGEMENT, LLC	0.16%	85.5K	86.36K	-550	-0.64%
Dec 31, 2023	ORBIMED ADVISORS LLC	18.48%	10.12M	10.23M	0	0
Dec 31, 2023	D. E. SHAW & CO., INC.	0%	0	-	-10.03K	-100.00%
Dec 31, 2023	US BANCORP \DE\	0%	0	-	-500	-100.00%
Dec 31, 2023	QUBE RESEARCH & TECHNOLOGIES LTD	0%	4	4	0	0
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0%	32	32	31	+3,100.00%

Insiders

Insiders	Designation	Shares Held
ORBIMED CAPITAL GP VII LLC		6.54M
ORBIMED ADVISORS LLC	10 percent owner	6.07M
FRAZIER LIFE SCIENCES IX, L.P.	10 percent owner	5.01M
HERON PATRICK J		5.01M
WOIWODE THOMAS		933.35K
VERSANT VENTURE CAPITAL VI, L.P.	10 percent owner	933.35K
YAMADA TADATAKA	director	656.15K
LYNX1 CAPITAL MANAGEMENT LP	10 percent owner	623.7K
QUIGLEY JILL M.	Chief Operating Officer	295.28K
FORMAN MARK S	CHIEF MEDICAL OFFICER	48.63K
CALE EDGAR B.	GC & Corporate Secretary	46K
FOTOPOULOS ALEXANDROS	Chief Technical Officer	28.69K
KING SIMONA	Chief Financial Officer	23.99K
COUNTOURIOTIS ATHENA	director	18.9K
GOLDSMITH BRUCE A	CEO and President	15.98K
CHOU WILLIAM	PRESIDENT AND CEO	6.52K
MORRIS RICHARD STEVEN	Chief Financial Officer	5.45K
BORTHWICK KATHLEEN	CFO	5.4K
ISLAM SAQIB	director	5K
TOERNSEN MONIKA MARIA	Chief Commercial Officer	3.32K
RATCLIFFE LIAM	director	2.8K
KAPADIA SANDIP	director	0
ROMANO GARY	Chief Medical Officer	0

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Jan 08, 2026	BORTHWICK KATHLEEN	SALE	18.44	2.06K	38.02K	5.4K
Jan 08, 2026	CHOU WILLIAM	SALE	18.44	4.08K	75.16K	6.52K
Sep 15, 2025	LYNX1 CAPITAL MANAGEMENT LP	PURCHASE	6.99	11.9K	83.18K	623.7K
Sep 12, 2025	LYNX1 CAPITAL MANAGEMENT LP	PURCHASE	6.99	19.78K	138.3K	611.8K
Sep 11, 2025	LYNX1 CAPITAL MANAGEMENT LP	PURCHASE	6.96	325	2.26K	592.02K
Jul 24, 2025	LYNX1 CAPITAL MANAGEMENT LP	PURCHASE	5.71	66.42K	379.45K	591.7K
Jul 23, 2025	LYNX1 CAPITAL MANAGEMENT LP	PURCHASE	5.74	49.3K	283.03K	525.27K
Jul 22, 2025	LYNX1 CAPITAL MANAGEMENT LP	PURCHASE	5.44	13.12K	71.34K	475.97K
Jun 26, 2025	ORBIMED ADVISORS LLC	SALE	0.33	213.26K	70.37K	6.07M
Jun 25, 2025	ORBIMED ADVISORS LLC	SALE	0.33	138.8K	45.8K	6.28M
Jun 24, 2025	ORBIMED ADVISORS LLC	SALE	0.35	231.6K	81.06K	6.42M
Apr 24, 2025	ORBIMED ADVISORS LLC	SALE	0.32	68.2K	21.82K	6.65M
Apr 23, 2025	ORBIMED ADVISORS LLC	SALE	0.34	89.33K	30.37K	6.72M
Apr 22, 2025	ORBIMED ADVISORS LLC	SALE	0.34	78.05K	26.54K	6.81M
Apr 17, 2025	ORBIMED ADVISORS LLC	SALE	0.33	77.09K	25.44K	6.89M
Apr 16, 2025	ORBIMED ADVISORS LLC	SALE	0.33	61.64K	20.34K	6.96M
Apr 15, 2025	ORBIMED ADVISORS LLC	SALE	0.38	10.33K	3.92K	7.02M
Feb 11, 2025	BORTHWICK KATHLEEN	SALE	0.53	3.18K	1.69K	41.28K
Jan 14, 2025	ORBIMED ADVISORS LLC	SALE	0.60	79.02K	47.41K	7.03M
Jan 13, 2025	ORBIMED ADVISORS LLC	SALE	0.64	17.99K	11.51K	7.11M
Jan 10, 2025	ORBIMED ADVISORS LLC	SALE	0.66	126.21K	83.3K	7.13M
Jan 08, 2025	ORBIMED ADVISORS LLC	SALE	0.68	75.01K	51K	7.26M
Jan 07, 2025	ORBIMED ADVISORS LLC	SALE	0.71	52.54K	37.3K	7.33M
Jan 06, 2025	ORBIMED ADVISORS LLC	SALE	0.77	19.48K	15K	7.39M
Dec 27, 2024	LYNX1 CAPITAL MANAGEMENT LP	PURCHASE	0.65	373.65K	241.04K	9.26M
Dec 20, 2024	ORBIMED ADVISORS LLC	SALE	0.60	230.32K	138.19K	7.4M
Dec 11, 2024	ORBIMED ADVISORS LLC	SALE	0.80	80	64	7.64M
Dec 10, 2024	ORBIMED ADVISORS LLC	SALE	0.80	8.02K	6.41K	7.64M
Dec 09, 2024	ORBIMED ADVISORS LLC	SALE	0.84	54.18K	45.51K	7.64M
Dec 06, 2024	ORBIMED ADVISORS LLC	SALE	0.82	20.9K	17.14K	7.7M
Dec 04, 2024	ORBIMED ADVISORS LLC	SALE	0.79	76.2K	60.2K	7.72M
Nov 27, 2024	LYNX1 CAPITAL MANAGEMENT LP	PURCHASE	0.67	29.3K	19.66K	8.88M
Nov 26, 2024	LYNX1 CAPITAL MANAGEMENT LP	PURCHASE	0.71	167.06K	118.19K	8.85M
Nov 25, 2024	LYNX1 CAPITAL MANAGEMENT LP	PURCHASE	0.56	260K	146.66K	8.69M
Sep 19, 2024	ORBIMED ADVISORS LLC	SALE	0.71	39.3K	27.9K	7.79M
Sep 18, 2024	ORBIMED ADVISORS LLC	SALE	0.73	25.63K	18.71K	7.83M
Sep 17, 2024	ORBIMED ADVISORS LLC	SALE	0.73	111.4K	81.32K	7.86M
Sep 16, 2024	ORBIMED ADVISORS LLC	SALE	0.74	63.1K	46.69K	7.97M
Feb 13, 2024	FORMAN MARK S	SALE	0.97	1.64K	1.59K	48.63K
Feb 13, 2024	BORTHWICK KATHLEEN	SALE	0.97	1.47K	1.43K	28.47K
Jan 02, 2024	CALE EDGAR B.	SALE	0.91	15.81K	14.39K	46K
Jan 02, 2024	BORTHWICK KATHLEEN	SALE	0.91	10.67K	9.71K	25.94K
Jan 02, 2024	FORMAN MARK S	SALE	0.91	15.81K	14.39K	45.27K
Jul 28, 2023	KING SIMONA	SALE	0.88	11.45K	10.08K	23.99K
Jun 28, 2023	ORBIMED ADVISORS LLC	PURCHASE	0.84	575.2K	483.16K	8.03M
Jun 27, 2023	ORBIMED ADVISORS LLC	PURCHASE	0.84	617.38K	518.6K	7.46M
Jun 16, 2023	FOTOPOULOS ALEXANDROS	SALE	0.93	4.05K	3.78K	28.69K
Apr 18, 2023	KING SIMONA	SALE	1.05	2.05K	2.16K	2.05K
Dec 01, 2022	KAPADIA SANDIP	SALE	1.19	5K	5.96K	0
Nov 22, 2022	FOTOPOULOS ALEXANDROS	SALE	1.33	3.72K	4.95K	20.25K
Sep 19, 2022	TOERNSEN MONIKA MARIA	SALE	1.51	1.68K	2.54K	3.32K
May 04, 2022	ORBIMED ADVISORS LLC	PURCHASE	1.94	303.5K	588.79K	6.84M
May 03, 2022	ORBIMED ADVISORS LLC	PURCHASE	1.93	221.5K	427.5K	6.54M
May 03, 2022	ORBIMED CAPITAL GP VII LLC	PURCHASE	1.93	221.5K	427.5K	6.54M
Mar 21, 2022	GOLDSMITH BRUCE A	PURCHASE	3.15	10K	31.5K	15.98K
Jan 20, 2022	ORBIMED ADVISORS LLC	PURCHASE	5.42	369.1K	2M	6.63M
Jan 19, 2022	ORBIMED ADVISORS LLC	PURCHASE	5.11	43.3K	221.26K	6.27M
Jan 18, 2022	ORBIMED ADVISORS LLC	PURCHASE	5.46	114.7K	626.26K	6.22M
Jan 14, 2022	ORBIMED ADVISORS LLC	PURCHASE	5.60	10.3K	57.68K	6.11M
Jan 13, 2022	ORBIMED ADVISORS LLC	PURCHASE	5.52	41.8K	230.74K	6.1M
Jan 12, 2022	ORBIMED ADVISORS LLC	PURCHASE	5.65	100K	565K	6.06M
Jan 11, 2022	ORBIMED ADVISORS LLC	PURCHASE	5.53	8.2K	45.35K	5.96M
May 21, 2021	GOLDSMITH BRUCE A	PURCHASE	13.12	2K	26.23K	5.98K
May 21, 2021	MORRIS RICHARD STEVEN	PURCHASE	13.82	2.17K	30K	5.45K
Mar 15, 2021	ROMANO GARY	SALE	21.86	1.62K	35.35K	0
Jan 20, 2021	QUIGLEY JILL M.	SALE	30.01	1.3K	39.01K	295.28K
Jan 14, 2021	QUIGLEY JILL M.	SALE	30.10	16.3K	490.57K	296.58K
Mar 24, 2020	COUNTOURIOTIS ATHENA	PURCHASE	14.97	10K	149.75K	18.9K
Mar 03, 2020	QUIGLEY JILL M.	PURCHASE	18.00	1K	18K	1K
Mar 03, 2020	YAMADA TADATAKA	PURCHASE	18.00	6.5K	117K	656.15K
Mar 03, 2020	HERON PATRICK J	PURCHASE	18.00	550K	9.9M	5.01M
Mar 03, 2020	WOIWODE THOMAS	PURCHASE	18.00	225K	4.05M	933.35K
Mar 03, 2020	RATCLIFFE LIAM	PURCHASE	18.00	2.8K	50.4K	2.8K
Mar 03, 2020	VERSANT VENTURE CAPITAL VI, L.P.	PURCHASE	18.00	225K	4.05M	933.35K
Mar 03, 2020	MORRIS RICHARD STEVEN	PURCHASE	18.00	400	7.2K	400
Mar 03, 2020	KAPADIA SANDIP	PURCHASE	18.00	5K	90K	5K
Mar 03, 2020	ISLAM SAQIB	PURCHASE	18.00	5K	90K	5K
Mar 03, 2020	GOLDSMITH BRUCE A	PURCHASE	18.00	1.1K	19.8K	1.1K
Mar 03, 2020	FOTOPOULOS ALEXANDROS	PURCHASE	18.00	5.5K	99K	5.5K
Mar 03, 2020	COUNTOURIOTIS ATHENA	PURCHASE	18.00	8.9K	160.2K	8.9K
Mar 03, 2020	CALE EDGAR B.	PURCHASE	18.00	2K	36K	2K
Mar 03, 2020	FRAZIER LIFE SCIENCES IX, L.P.	PURCHASE	18.00	550K	9.9M	5.01M
Feb 28, 2020	ORBIMED ADVISORS LLC	PURCHASE	18.00	373.3K	6.72M	373.3K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE32.01K3

SALES6.14K2

NET SHARES25.87K1

SHARES HELD1.84M5

% NET SHARES-98.59%-80%

PASG Stock Ownership Breakdown

Passage Bio

Stock Outstanding Shares

Market Insider

Institutional Ownership

Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions

Stock Outstanding Shares

Market Insider

Institutional Ownership

Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions