How many institutions own NUVL stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own NUVL shares is 298, representing 109.13% of the company's common stock.

Who are the major shareholders selling Nuvalent, Inc. stock?

FIRST TURN MANAGEMENT, LLC, in the last quarter, reduced its stake in NUVL by -6.6% restricting it's holding to 368.7 thousand shares of worth nearly $37.09M. ARROWMARK COLORADO HOLDINGS LLC also lessened -18.36% of the NUVL shares from its portfolio, reducing its holding to 296.03 thousand shares of worth $29.78M. BRAIDWELL LP also shunned NUVL shares holding by -18.91% last quarter which brought its holding to 821.41 thousand shares worth $82.63M.

Investors who are buying NUVL stock?

As per its latest 13F filing, FMR LLC increased its stake in NUVL by 8.39% in the last quarter. The institutional holder raised its holding to 10.85 million shares having worth more than $1.09B. also added 100% more shares of NUVL to its portfolio, raising its holding to 269.04 thousand shares of worth $27.06B. AMERICAN CENTURY COMPANIES INC also increased its NUVL shares holding by 3.11% which brought its holding to 374.23 thousand shares worth $37.64M.

NUVL's major insiders: who are they?

The insider with the most stakes in NUVL is Flynn James E , Director by Deputization at the company. Additionally, NUVL stock is highly held by director Hack Andrew A. F. and President and CEO Porter James Richard among others.

Did an insider recently sell NUVL stock?

Company executives, directors, and other insiders own 2.84% percent of Nuvalent, Inc.'s stock. Within the last six months, there have been 44 transaction(s) in which NUVL insiders have sold stock, totaling 506.88K shares. Insiders that have sold shares include NOCI DARLENE, MILLER DEBORAH ANN, and PORTER JAMES RICHARD.

Which insider recently purchased NUVL stock?

There have been 0 transaction(s) during the past 6-months in which Nuvalent, Inc. insiders have bought stock, totalling 0 shares

How much of NUVL does insiders own?

Around 12.04M Nuvalent, Inc. shares are held by insiders, which represents about 2.84% of NUVL stock.

Who is the insider with the largest stake?

NUVL Director by Deputization, Flynn James E holds the largest portfolio of the company's shares. NUVL shares owned by Flynn total nearly 8.3 million.

Which institution holds the most shares in NUVL?

FMR LLC is the largest institutional owner in NUVL which holds 10.85 million shares worth $1.09B or 15.04% of the total NUVL shares outstanding followed by with ownership of 269.04 thousand shares representing 0.37% of the NUVL ownership. FIRST TURN MANAGEMENT, LLC is the third largest stakeholder with 368.7 thousand shares or 0.51% of the ownership worth more than $37.09M.

Is Nuvalent, Inc. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the NUVL is concerned, it is a stock which is optionable.

Is there a short position on NUVL's shares?

Number of NUVL shares short is 5.54M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding NUVL shares are there?

As of today, 66.67M shares of NUVL are outstanding.

Is there many float in NUVL stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, NUVL has 41.56M shares in float.

NUVL short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for NUVL is 11.1.

Nuvalent (NUVL) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares7.69

Short Percent Of Float17.88

Shares Outstanding66.67M

Shares Float41.56M

Shares Short5.54M

Short Ratio11.1

17.88%

Short % of Float

7.69%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

2.84% Percentage of Shares held by All Insiders

109.13% Percentage of Shares held by All Institutions

112.31% Percentage of Float held by Institutions

298

Number of Institutions Holding Shares

Institutional Ownership

About 109.13% of NUVL shares are held by financial institutions. FMR LLC is the top corporate investor, holding 10.85M shares valued at $1.09B. A 15.04% stake in Nuvalent, Inc. is owned by the company. owns 269.04K shares valued at $27.06B, which translates its holding of 0.37% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Dec 31, 2025	FMR LLC	15.04%	10.85M	1.09B	839.65K	+8.39%
Dec 31, 2025		0.37%	269.04K	27.06B	269.04K	+100.00%
Dec 31, 2025	FIRST TURN MANAGEMENT, LLC	0.51%	368.7K	37.09M	-26.06K	-6.60%
Dec 31, 2025	AMERICAN CENTURY COMPANIES INC	0.52%	374.23K	37.64M	11.3K	+3.11%
Dec 31, 2025	UBS GROUP AG	0.55%	399.05K	40.14M	185.93K	+87.24%
Dec 31, 2025	FRANKLIN RESOURCES INC	0.57%	411.35K	41.38M	251.22K	+156.88%
Dec 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.63%	453.31K	45.6M	48.76K	+12.05%
Dec 31, 2025	NORGES BANK	0.8%	574.24K	57.76M	574.24K	+100.00%
Dec 31, 2025	GOLDMAN SACHS GROUP INC	0.82%	594.46K	59.8M	150.02K	+33.76%
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.72%	1.24M	124.58M	144.24K	+13.18%
Dec 31, 2025	STATE STREET CORP	2.58%	1.86M	187.57M	289.93K	+18.41%
Dec 31, 2025	JPMORGAN CHASE & CO	3.06%	2.21M	221.83M	531.24K	+31.73%
Dec 31, 2025	BLACKROCK, INC.	6.66%	4.81M	483.36M	719.47K	+17.61%
Dec 31, 2025	VANGUARD GROUP INC	7.27%	5.24M	527.52M	639.26K	+13.88%
Dec 31, 2025	FRONTIER CAPITAL MANAGEMENT CO LLC	0.37%	270.47K	27.21M	270.47K	+100.00%
Dec 31, 2025	ARROWMARK COLORADO HOLDINGS LLC	0.41%	296.03K	29.78M	-66.56K	-18.36%
Dec 31, 2025	NORTHERN TRUST CORP	0.57%	410.45K	41.29M	28.95K	+7.59%
Dec 31, 2025	INVESCO LTD.	0.61%	439.3K	44.19M	405.54K	+1,201.36%
Dec 31, 2025	HOOD RIVER CAPITAL MANAGEMENT LLC	0.66%	475.44K	47.82M	475.44K	+100.00%
Dec 31, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	0.67%	483.5K	48.64M	266.95K	+123.27%
Dec 31, 2025	FAIRMOUNT FUNDS MANAGEMENT LLC	1.01%	727.56K	73.19M	0	0
Dec 31, 2025	ALLIANCEBERNSTEIN L.P.	1.09%	785.45K	79.01M	735.48K	+1,471.90%
Dec 31, 2025	BRAIDWELL LP	1.14%	821.41K	82.63M	-191.58K	-18.91%
Dec 31, 2025	BELLEVUE GROUP AG	1.44%	1.04M	104.36M	1.04M	+100.00%
Dec 31, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	1.83%	1.32M	132.78M	298.73K	+29.25%
Dec 31, 2025	JANUS HENDERSON GROUP PLC	2.08%	1.5M	150.82M	-689.1K	-31.48%
Dec 31, 2025	POLAR CAPITAL HOLDINGS PLC	2.13%	1.54M	154.59M	514.63K	+50.34%
Dec 31, 2025	PERCEPTIVE ADVISORS LLC	2.31%	1.67M	167.49M	102.77K	+6.58%
Dec 31, 2025	COMMODORE CAPITAL LP	0.76%	550K	55.32M	-850K	-60.71%
Dec 31, 2025	AMERIPRISE FINANCIAL INC	0.78%	564.3K	56.76M	37.25K	+7.07%
Dec 31, 2025	RA CAPITAL MANAGEMENT, L.P.	2.61%	1.88M	189.11M	633.6K	+50.83%
Dec 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	2.98%	2.15M	215.96M	336.52K	+18.59%
Dec 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	3.41%	2.46M	247.63M	160.96K	+7.00%
Dec 31, 2025	PARADIGM BIOCAPITAL ADVISORS LP	7.3%	5.27M	530.05M	0	0
Dec 31, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	23.91%	17.25M	1.74B	-742.57K	-4.13%
Dec 31, 2025	MARSHALL WACE, LLP	0.03%	23.93K	2.41M	23.93K	+100.00%
Dec 31, 2025	SEVEN GRAND MANAGERS, LLC	0.03%	25K	2.51M	25K	+100.00%
Dec 31, 2025	ALYESKA INVESTMENT GROUP, L.P.	0.04%	25.53K	2.57M	-75.53K	-74.74%
Dec 31, 2025	RHENMAN & PARTNERS ASSET MANAGEMENT AB	0.23%	163.35K	16.43M	110.85K	+211.14%
Dec 31, 2025	ABRDN PLC	0.23%	165.18K	16.62M	88.49K	+115.39%
Dec 31, 2025	CITADEL ADVISORS LLC	0.27%	195.16K	19.63M	164.93K	+545.66%
Dec 31, 2025	MORGAN STANLEY	0.37%	267.39K	26.9M	-7.72K	-2.81%
Dec 31, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.04%	27.63K	2.78M	2.54K	+10.14%
Dec 31, 2025	LORD, ABBETT & CO. LLC	0.39%	281.22K	28.29M	281.22K	+100.00%
Dec 31, 2025	TRI LOCUM PARTNERS LP	0.43%	307.37K	30.92M	307.37K	+100.00%
Dec 31, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.89%	643K	64.68M	68.5K	+11.92%
Dec 31, 2025	TEMA ETFS LLC	0.05%	36.46K	3.67M	3.45K	+10.46%
Dec 31, 2025	LEGAL & GENERAL GROUP PLC	0.06%	41.65K	4.19M	-1.63K	-3.77%
Dec 31, 2025	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.06%	42.36K	4.26M	18.57K	+78.08%
Dec 31, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.06%	45.95K	4.62M	-2.04K	-4.24%
Dec 31, 2025	UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH	0.06%	46.69K	4.7M	13.61K	+41.13%
Dec 31, 2025	ENSIGN PEAK ADVISORS, INC	0.08%	54.2K	5.45M	-10.18K	-15.81%
Dec 31, 2025	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	0.08%	61.13K	6.15M	60.82K	+19,555.95%
Dec 31, 2025	SQUAREPOINT OPS LLC	0.09%	61.75K	6.21M	54.32K	+731.60%
Dec 31, 2025	JUMP FINANCIAL, LLC	0.04%	27.96K	2.81M	24.44K	+695.08%
Dec 31, 2025	WOODLINE PARTNERS LP	0.85%	610.46K	61.41M	-459.06K	-42.92%
Dec 31, 2025	WELLS FARGO & COMPANY/MN	0.09%	62.16K	6.25M	31.28K	+101.33%
Dec 31, 2025	RHUMBLINE ADVISERS	0.09%	63.84K	6.42B	-1.38K	-2.11%
Dec 31, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.11%	78.28K	7.86M	13.81K	+21.43%
Dec 31, 2025	SWISS NATIONAL BANK	0.11%	78.9K	7.94M	1.7K	+2.20%
Dec 31, 2025	MILLENNIUM MANAGEMENT LLC	0.11%	81.87K	8.23M	81.87K	+100.00%
Dec 31, 2025	DEUTSCHE BANK AG\	0.12%	83.04K	8.35M	11.34K	+15.81%
Dec 31, 2025	FISHER ASSET MANAGEMENT, LLC	0.14%	100.71K	10.13M	-5.72K	-5.37%
Dec 31, 2025	NUVEEN, LLC	0.15%	107.62K	10.83M	15.99K	+17.45%
Dec 31, 2025	PARKMAN HEALTHCARE PARTNERS LLC	0.16%	118.71K	11.94M	-1.48K	-1.23%
Dec 31, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.17%	124.56K	12.53M	59.14K	+90.40%
Dec 31, 2025	BARCLAYS PLC	0.17%	125.33K	12.61M	-1.55K	-1.22%
Dec 31, 2025	RAYMOND JAMES FINANCIAL INC	0.21%	151.97K	15.26M	20.94K	+15.98%
Dec 31, 2025	TD ASSET MANAGEMENT INC	0.21%	153.36K	15.43M	43.78K	+39.95%
Dec 31, 2025	NICHOLAS INVESTMENT PARTNERS, LP	0.22%	160.48K	16.14M	36.31K	+29.24%
Dec 31, 2025	BANK OF NEW YORK MELLON CORP	0.22%	161.6K	16.26M	16.2K	+11.14%
Dec 31, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.24%	172.53K	17.35M	37.79K	+28.04%
Dec 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.24%	174.07K	17.51M	36.12K	+26.19%
Dec 31, 2025	BANK OF AMERICA CORP /DE/	0.25%	180.37K	18.14M	19.18K	+11.90%
Dec 31, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.43%	311.43K	31.33M	-60.87K	-16.35%
Dec 31, 2025	AFFINITY ASSET ADVISORS, LLC	0.45%	322.63K	32.45M	-61.78K	-16.07%
Dec 31, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.49%	355.68K	35.78M	-28.9K	-7.51%
Dec 31, 2025	CANDRIAM S.C.A.	0.5%	358.01K	36.01M	28.29K	+8.58%
Dec 31, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.05%	32.46K	3.27M	4.4K	+15.67%
Dec 31, 2025	CITIGROUP INC	0.05%	35.83K	3.6M	671	+1.91%
Dec 31, 2025	VERITION FUND MANAGEMENT LLC	0.1%	72.02K	7.24M	66.31K	+1,162.98%
Sep 30, 2025	RHUMBLINE ADVISERS	0.09%	65.21K	5.64M	-817	-1.24%
Sep 30, 2025	DEUTSCHE BANK AG\	0.1%	71.7K	6.2M	41.73K	+139.27%
Sep 30, 2025	ABRDN PLC	0.11%	76.69K	6.63M	0	0
Sep 30, 2025	NORTHERN TRUST CORP	0.53%	381.5K	32.99M	39.72K	+11.62%
Sep 30, 2025	TD ASSET MANAGEMENT INC	0.15%	109.58K	9.48M	10.68K	+10.80%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.22%	161.19K	13.94M	-96.75K	-37.51%
Sep 30, 2025	UBS GROUP AG	0.3%	213.12K	18.43M	76.38K	+55.85%
Sep 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.54%	384.58K	33.26M	-205.26K	-34.80%
Sep 30, 2025	STATE STREET CORP	2.19%	1.57M	136.18M	84.47K	+5.67%
Sep 30, 2025	FRANKLIN RESOURCES INC	0.22%	160.13K	13.85M	504	+0.32%
Sep 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0.13%	92.48K	8M	10.88K	+13.33%
Sep 30, 2025	MORGAN STANLEY	0.38%	275.11K	23.79M	-147.61K	-34.92%
Sep 30, 2025	CANDRIAM S.C.A.	0.46%	329.72K	28.51M	28.46K	+9.45%
Sep 30, 2025	ARROWMARK COLORADO HOLDINGS LLC	0.5%	362.59K	31.36M	-7.27K	-1.97%
Sep 30, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	0.3%	216.56K	18.73M	134	+0.06%
Sep 30, 2025	BAKER BROS. ADVISORS LP	0.2%	143.94K	12.45M	0	0
Sep 30, 2025	AMERICAN CENTURY COMPANIES INC	0.51%	362.93K	31.39M	-11.77K	-3.14%
Sep 30, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.52%	372.3K	32.2M	136.72K	+58.03%
Sep 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.54%	384.42K	33.24M	-30.58K	-7.37%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.56%	404.55K	34.99M	58.05K	+16.75%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	0.62%	444.44K	38.43M	-91.01K	-17.00%
Sep 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.8%	574.5K	49.68M	-3K	-0.52%
Sep 30, 2025	FAIRMOUNT FUNDS MANAGEMENT LLC	1.01%	727.56K	62.92M	0	0
Sep 30, 2025	BRAIDWELL LP	1.41%	1.01M	87.6M	-162.89K	-13.85%
Sep 30, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	1.42%	1.02M	88.32M	-73.33K	-6.70%
Sep 30, 2025	POLAR CAPITAL HOLDINGS PLC	1.42%	1.02M	88.4M	206.14K	+25.26%
Sep 30, 2025	WOODLINE PARTNERS LP	1.49%	1.07M	92.49M	165.29K	+18.28%
Sep 30, 2025	COMMODORE CAPITAL LP	1.95%	1.4M	121.07M	25K	+1.82%
Sep 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	2.52%	1.81M	156.57M	15.05K	+0.84%
Sep 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	3.2%	2.3M	198.98M	724.49K	+45.96%
Sep 30, 2025	PARADIGM BIOCAPITAL ADVISORS LP	7.33%	5.27M	455.7M	0	0
Sep 30, 2025	HIGHVISTA STRATEGIES LLC	0.13%	93.29K	8.07M	42.83K	+84.89%
Sep 30, 2025	ALYESKA INVESTMENT GROUP, L.P.	0.14%	101.07K	8.74M	51.07K	+102.13%
Sep 30, 2025	FISHER ASSET MANAGEMENT, LLC	0.15%	106.42K	9.2M	-8.34K	-7.26%
Sep 30, 2025	PARKMAN HEALTHCARE PARTNERS LLC	0.17%	120.19K	10.39M	567	+0.47%
Sep 30, 2025	NICHOLAS INVESTMENT PARTNERS, LP	0.17%	124.18K	10.74M	20.46K	+19.72%
Sep 30, 2025	BARCLAYS PLC	0.18%	126.88K	10.97M	-22.73K	-15.19%
Sep 30, 2025	AMERIPRISE FINANCIAL INC	0.73%	527.05K	45.58M	42.71K	+8.82%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.52%	1.09M	94.62M	97.15K	+9.75%
Sep 30, 2025	RA CAPITAL MANAGEMENT, L.P.	1.74%	1.25M	107.79M	1.25M	+100.00%
Sep 30, 2025	PERCEPTIVE ADVISORS LLC	2.17%	1.56M	135.11M	187.16K	+13.61%
Sep 30, 2025	JPMORGAN CHASE & CO	2.33%	1.67M	144.77M	476.82K	+39.83%
Sep 30, 2025	VESTAL POINT CAPITAL, LP	1.53%	1.1M	95.13M	25K	+2.33%
Sep 30, 2025	JANUS HENDERSON GROUP PLC	3.05%	2.19M	189.34M	406.09K	+22.78%
Sep 30, 2025	BLACKROCK, INC.	5.69%	4.09M	353.34M	39.54K	+0.98%
Sep 30, 2025	VANGUARD GROUP INC	6.41%	4.61M	398.24M	80.88K	+1.79%
Sep 30, 2025	FMR LLC	13.94%	10.01M	865.94M	44.39K	+0.45%
Sep 30, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	25.04%	17.99M	1.56B	0	0
Sep 30, 2025	RAYMOND JAMES FINANCIAL INC	0.18%	131.03K	11.33M	-7.94K	-5.71%
Sep 30, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.19%	134.74K	11.65M	11.52K	+9.35%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.19%	137.95K	11.93M	2.33K	+1.72%
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.2%	145.4K	12.57M	2.03K	+1.42%
Sep 30, 2025	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0.02%	11.89K	1.03M	2.07K	+21.10%
Sep 30, 2025	LEGATO CAPITAL MANAGEMENT LLC	0.02%	12.65K	1.09M	3.78K	+42.61%
Sep 30, 2025	GUGGENHEIM CAPITAL LLC	0.02%	12.84K	1.11M	1.98K	+18.19%
Sep 30, 2025	HANDELSBANKEN FONDER AB	0.02%	13.9K	1.2M	1.9K	+15.83%
Sep 30, 2025	FIRST TURN MANAGEMENT, LLC	0.55%	394.75K	34.14M	73.96K	+23.05%
Sep 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.02%	14.95K	1.29M	-7.93K	-34.66%
Sep 30, 2025	HUDSON BAY CAPITAL MANAGEMENT LP	0.02%	15K	1.3M	15K	+100.00%
Sep 30, 2025	DEKABANK DEUTSCHE GIROZENTRALE	0.02%	17K	1.4M	0	0
Sep 30, 2025	SG AMERICAS SECURITIES, LLC	0.03%	18.84K	1.63M	18.84K	+100.00%
Sep 30, 2025	BRIDGEWATER ASSOCIATES, LP	0.03%	22.06K	1.91M	22.06K	+100.00%
Sep 30, 2025	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.03%	23.79K	2.06B	23.79K	+100.00%
Sep 30, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.03%	25.09K	2.17M	-619	-2.41%
Sep 30, 2025	JEFFERIES FINANCIAL GROUP INC.	0.04%	25.16K	2.18M	25.16K	+100.00%
Sep 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.04%	28.06K	2.43M	4.33K	+18.23%
Sep 30, 2025	NUVEEN, LLC	0.13%	91.63K	7.92M	-1.14K	-1.23%
Sep 30, 2025	FRED ALGER MANAGEMENT, LLC	0.12%	88.5K	7.65M	-2.94K	-3.21%
Sep 30, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	0.12%	88K	7.61M	-37K	-29.60%
Sep 30, 2025	SWISS NATIONAL BANK	0.11%	77.2K	6.68M	1.4K	+1.85%
Sep 30, 2025	STATE OF NEW JERSEY COMMON PENSION FUND D	0.04%	28.88K	2.5M	3.16K	+12.29%
Sep 30, 2025	DIMENSIONAL FUND ADVISORS LP	0.04%	29.53K	2.55M	7.16K	+32.03%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0.04%	30.87K	2.67M	-12.1K	-28.16%
Sep 30, 2025	ALPS ADVISORS INC	0.04%	30.89K	2.67M	-4.9K	-13.68%
Sep 30, 2025	TEMA ETFS LLC	0.05%	33.01K	2.85M	1.25K	+3.92%
Sep 30, 2025	NEOS INVESTMENT MANAGEMENT LLC	0.05%	33.01K	2.85M	1.25K	+3.92%
Sep 30, 2025	UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH	0.05%	33.08K	2.86M	2.52K	+8.23%
Sep 30, 2025	INVESCO LTD.	0.05%	33.76K	2.92M	-4.28K	-11.25%
Sep 30, 2025	CITIGROUP INC	0.05%	35.16K	3.04M	-104.03K	-74.74%
Sep 30, 2025	LEGAL & GENERAL GROUP PLC	0.06%	43.28K	3.74M	-1.55K	-3.47%
Sep 30, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.07%	47.98K	4.15M	-402	-0.83%
Sep 30, 2025	RHENMAN & PARTNERS ASSET MANAGEMENT AB	0.07%	52.5K	4.54M	0	0
Sep 30, 2025	ENSIGN PEAK ADVISORS, INC	0.09%	64.38K	5.57M	-30.46K	-32.12%
Jun 30, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	0.17%	125K	9.54M	-89.36K	-41.69%
Jun 30, 2025	COMMODORE CAPITAL LP	1.91%	1.38M	104.91M	-480K	-25.88%
Jun 30, 2025	JPMORGAN CHASE & CO	1.67%	1.2M	91.35M	1.1M	+1,073.82%
Jun 30, 2025	PERCEPTIVE ADVISORS LLC	1.91%	1.38M	104.93M	-258.79K	-15.84%
Jun 30, 2025	FMR LLC	13.88%	9.97M	760.62M	31.65K	+0.32%
Jun 30, 2025	VANGUARD GROUP INC	6.3%	4.52M	345.19M	84.29K	+1.90%
Jun 30, 2025	PARADIGM BIOCAPITAL ADVISORS LP	7.33%	5.27M	402.06M	0	0
Jun 30, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	1.52%	1.09M	83.52M	643.79K	+142.82%
Jun 30, 2025	VESTAL POINT CAPITAL, LP	1.5%	1.08M	82.02M	0	0
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.39%	996.85K	76.07M	103.39K	+11.57%
Jun 30, 2025	WOODLINE PARTNERS LP	1.26%	904.23K	68.99M	-301.3K	-24.99%
Jun 30, 2025	POLAR CAPITAL HOLDINGS PLC	1.14%	816.09K	62.27M	-130.64K	-13.80%
Jun 30, 2025	FAIRMOUNT FUNDS MANAGEMENT LLC	1.01%	727.56K	55.51M	0	0
Jun 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.82%	589.83K	45M	35.69K	+6.44%
Jun 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.8%	577.5K	44.06M	180.5K	+45.47%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.75%	535.45K	40.85M	81.83K	+18.04%
Jun 30, 2025	MORGAN STANLEY	0.59%	422.72K	32.25M	74.64K	+21.44%
Jun 30, 2025	NORTHERN TRUST CORP	0.48%	341.77K	26.08M	13.44K	+4.09%
Jun 30, 2025	FIRST TURN MANAGEMENT, LLC	0.45%	320.8K	24.48M	-11.13K	-3.35%
Jun 30, 2025	CANDRIAM S.C.A.	0.42%	301.26K	22.99M	-52.87K	-14.93%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0.36%	257.94K	19.68M	37.92K	+17.24%
Jun 30, 2025	FRANKLIN RESOURCES INC	0.22%	159.63K	12.18M	0	0
Jun 30, 2025	D. E. SHAW & CO., INC.	0.22%	156.79K	11.96M	25.83K	+19.72%
Jun 30, 2025	FARALLON CAPITAL MANAGEMENT LLC	0.21%	150K	11.45M	0	0
Jun 30, 2025	BARCLAYS PLC	0.21%	149.61K	11.42M	53.57K	+55.78%
Jun 30, 2025	BANK OF NEW YORK MELLON CORP	0.2%	143.38K	10.94M	28.55K	+24.86%
Jun 30, 2025	CITIGROUP INC	0.19%	139.19K	10.62M	-97.7K	-41.24%
Jun 30, 2025	RAYMOND JAMES FINANCIAL INC	0.19%	138.97K	10.6M	5.88K	+4.41%
Jun 30, 2025	UBS GROUP AG	0.19%	136.74K	10.43M	27.27K	+24.90%
Jun 30, 2025	BLACKROCK, INC.	5.63%	4.05M	308.73M	297.9K	+7.95%
Jun 30, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.17%	123.22K	9.4M	2.91K	+2.42%
Jun 30, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.33%	235.58K	17.97M	-203.44K	-46.34%
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	2.5%	1.8M	136.99M	344.77K	+23.77%
Jun 30, 2025	JANUS HENDERSON GROUP PLC	2.48%	1.78M	136.05M	472.39K	+36.05%
Jun 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	2.19%	1.58M	120.28M	133.99K	+9.29%
Jun 30, 2025	AMERIPRISE FINANCIAL INC	0.67%	484.34K	36.96M	204K	+72.77%
Jun 30, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	0.3%	216.42K	16.51M	-314.79K	-59.26%
Jun 30, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.24%	169.54K	12.94M	19.6K	+13.07%
Jun 30, 2025	STATE STREET CORP	2.07%	1.49M	113.71M	59.62K	+4.17%
Jun 30, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	2.01%	1.45M	110.43M	0	0
Jun 30, 2025	BRAIDWELL LP	1.64%	1.18M	89.72M	334.93K	+39.83%
Jun 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.58%	415K	31.66M	-45K	-9.78%
Jun 30, 2025	AMERICAN CENTURY COMPANIES INC	0.52%	374.7K	28.59M	92.65K	+32.85%
Jun 30, 2025	NORGES BANK	0.52%	374.6K	28.58M	374.6K	+100.00%
Jun 30, 2025	ARROWMARK COLORADO HOLDINGS LLC	0.51%	369.86K	28.22M	78.75K	+27.05%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.48%	346.51K	26.44M	28.74K	+9.05%
Jun 30, 2025	BAKER BROS. ADVISORS LP	0.2%	143.94K	10.98M	143.94K	+100.00%
Jun 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.19%	135.61K	10.35M	76.83K	+130.72%
Jun 30, 2025	PARKMAN HEALTHCARE PARTNERS LLC	0.17%	119.62K	9.13M	9.64K	+8.76%
Jun 30, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	25.04%	17.99M	1.37B	0	0
Mar 31, 2025	LORD, ABBETT & CO. LLC	0.26%	184.97K	13.12M	-112.62K	-37.84%
Mar 31, 2025	FRED ALGER MANAGEMENT, LLC	0.26%	187.9K	13.33M	-120.16K	-39.00%
Mar 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	2.03%	1.45M	102.88M	152.69K	+11.76%
Mar 31, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	2.02%	1.45M	102.64M	0	0
Mar 31, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.77%	554.14K	39.3M	-87.64K	-13.66%
Mar 31, 2025	MORGAN STANLEY	0.49%	348.08K	24.69M	125.8K	+56.59%
Mar 31, 2025	NORTHERN TRUST CORP	0.46%	328.33K	23.29M	-7.22K	-2.15%
Mar 31, 2025	ARROWMARK COLORADO HOLDINGS LLC	0.41%	291.1K	20.65M	-4.25K	-1.44%
Mar 31, 2025	AMERICAN CENTURY COMPANIES INC	0.39%	282.05K	20M	95.66K	+51.32%
Mar 31, 2025	AMERIPRISE FINANCIAL INC	0.39%	280.34K	19.88M	42.79K	+18.01%
Mar 31, 2025	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.35%	247.05K	17.52M	76.2K	+44.60%
Mar 31, 2025	CITIGROUP INC	0.33%	236.89K	16.8M	112.52K	+90.47%
Mar 31, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	0.3%	214.36K	15.2M	110K	+105.41%
Mar 31, 2025	POLAR CAPITAL HOLDINGS PLC	1.32%	946.72K	67.14M	0	0
Mar 31, 2025	JANE STREET GROUP, LLC	0.27%	191.3K	13.57M	43K	+29.00%
Mar 31, 2025	STEMPOINT CAPITAL LP	0.27%	190.4K	13.5M	45.17K	+31.10%
Mar 31, 2025	FIRST TURN MANAGEMENT, LLC	0.46%	331.93K	23.54M	22.41K	+7.24%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.63%	453.62K	32.17M	159.87K	+54.43%
Mar 31, 2025	AFFINITY ASSET ADVISORS, LLC	0.64%	460K	32.62M	175K	+61.40%
Mar 31, 2025	PERCEPTIVE ADVISORS LLC	2.28%	1.63M	115.88M	-986.01K	-37.63%
Mar 31, 2025	COMMODORE CAPITAL LP	2.59%	1.86M	131.56M	233.4K	+14.39%
Mar 31, 2025	BLACKROCK, INC.	5.23%	3.75M	265.83M	-103.22K	-2.68%
Mar 31, 2025	TWO SIGMA INVESTMENTS, LP	0.22%	159.12K	11.29M	-54.76K	-25.60%
Mar 31, 2025	VANGUARD GROUP INC	6.2%	4.44M	314.87M	-60.03K	-1.33%
Mar 31, 2025	PARADIGM BIOCAPITAL ADVISORS LP	7.36%	5.27M	373.71M	-93.95K	-1.75%
Mar 31, 2025	FMR LLC	13.88%	9.94M	704.75M	282.87K	+2.93%
Mar 31, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	25.12%	17.99M	1.28B	0	0
Mar 31, 2025	FRANKLIN RESOURCES INC	0.22%	159.63K	11.32M	2	0.00%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0.31%	220.02K	15.6M	-42.75K	-16.27%
Mar 31, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.61%	439.02K	31.14M	39K	+9.75%
Mar 31, 2025	FAIRMOUNT FUNDS MANAGEMENT LLC	1.02%	727.56K	51.6M	-590.1K	-44.78%
Mar 31, 2025		0.63%	450K	31.91M	-670.19K	-59.83%
Mar 31, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	0.63%	450.77K	31.97M	450.77K	+100.00%
Mar 31, 2025	FARALLON CAPITAL MANAGEMENT LLC	0.21%	150K	10.64M	0	0
Mar 31, 2025	SCHONFELD STRATEGIC ADVISORS LLC	0.26%	184.8K	13.11M	184.8K	+100.00%
Mar 31, 2025	SAMLYN CAPITAL, LLC	0.43%	309.59K	21.96M	-443	-0.14%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.44%	317.76K	22.54M	-5.81K	-1.79%
Mar 31, 2025	VESTAL POINT CAPITAL, LP	1.5%	1.08M	76.24M	475K	+79.17%
Mar 31, 2025	CANDRIAM S.C.A.	0.49%	354.13K	25.11M	-13.97K	-3.79%
Mar 31, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.55%	397K	28.16M	-283K	-41.62%
Mar 31, 2025	MARSHALL WACE, LLP	0.59%	421.51K	29.89M	60.47K	+16.75%
Mar 31, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	0.6%	427.53K	30.32M	-2.46K	-0.57%
Mar 31, 2025	LOGOS GLOBAL MANAGEMENT LP	0.7%	500K	35.46M	500K	+100.00%
Mar 31, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	0.74%	531.21K	37.67M	-262.21K	-33.05%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.25%	893.46K	63.38M	21.97K	+2.52%
Mar 31, 2025	WOODLINE PARTNERS LP	1.68%	1.21M	85.5M	604	+0.05%
Mar 31, 2025	JANUS HENDERSON GROUP PLC	1.83%	1.31M	95.73M	1.29M	+7,785.15%
Mar 31, 2025	STATE STREET CORP	2%	1.43M	101.46M	-59.02K	-3.96%
Mar 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	2.01%	1.44M	102.29M	157.81K	+12.28%
Mar 31, 2025	BRAIDWELL LP	1.17%	840.95K	59.64M	599.71K	+248.60%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.05%	27.3K	2.05M	-12.97K	-32.21%
Mar 31, 2024	CREDIT SUISSE AG/	0.05%	28.57K	2.15M	680	+2.44%
Mar 31, 2024	SEI INVESTMENTS CO	0.05%	31.06K	2.34B	1.68K	+5.72%
Mar 31, 2024	BALYASNY ASSET MANAGEMENT L.P.	0.05%	31.08K	2.33M	31.08K	+100.00%
Mar 31, 2024	STATE OF NEW JERSEY COMMON PENSION FUND D	0.06%	32.19K	2.42M	32.19K	+100.00%
Mar 31, 2024	JPMORGAN CHASE & CO	0.06%	34.89K	2.62M	-14.46K	-29.30%
Mar 31, 2024	EAM INVESTORS, LLC	0.06%	34.98K	2.63M	-15.2K	-30.29%
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	0.06%	37.17K	2.79M	-28.92K	-43.76%
Mar 31, 2024	HAP TRADING, LLC	0.06%	37.5K	113.44K	37.5K	+100.00%
Mar 31, 2024	RHUMBLINE ADVISERS	0.07%	39.19K	2.94M	1.88K	+5.03%
Mar 31, 2024	EAM GLOBAL INVESTORS LLC	0.08%	45.29K	3.4M	-17.36K	-27.71%
Mar 31, 2024	SWISS NATIONAL BANK	0.09%	50.9K	3.82M	400	+0.79%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.11%	64.21K	4.82M	127	+0.20%
Mar 31, 2024	UBS GROUP AG	0.14%	84.02K	6.31M	3.39K	+4.20%
Mar 31, 2024	RHENMAN & PARTNERS ASSET MANAGEMENT AB	0.15%	87.5K	6.57M	-25.43K	-22.52%
Mar 31, 2024	FRANKLIN RESOURCES INC	0.33%	194.04K	14.57M	18.6K	+10.60%
Mar 31, 2024	BANK OF MONTREAL /CAN/	0.33%	194.18K	14.6M	105.1K	+117.99%
Mar 31, 2024	WELLINGTON MANAGEMENT GROUP LLP	1.02%	593.6K	44.57M	-419.8K	-41.42%
Mar 31, 2024	DRIEHAUS CAPITAL MANAGEMENT LLC	1.16%	672.88K	50.53M	-264.85K	-28.24%
Mar 31, 2024	CITIGROUP INC	0.18%	102.43K	7.69M	33.58K	+48.76%
Mar 31, 2024	D. E. SHAW & CO., INC.	0.77%	445.38K	33.44M	-22.8K	-4.87%
Mar 31, 2024	BLACKROCK INC.	4.65%	2.71M	203.38M	-12.74K	-0.47%
Mar 31, 2024	PERCEPTIVE ADVISORS LLC	4.78%	2.78M	209.01M	-134.54K	-4.61%
Mar 31, 2024	VANGUARD GROUP INC	5.86%	3.41M	256.21M	72.22K	+2.16%
Mar 31, 2024	PARADIGM BIOCAPITAL ADVISORS LP	7.18%	4.18M	313.71M	319.82K	+8.29%
Mar 31, 2024	FMR LLC	15.11%	8.79M	660.41M	69.79K	+0.80%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.16%	90.26K	6.78M	-335	-0.37%
Mar 31, 2024	UBS ASSET MANAGEMENT AMERICAS INC	0.17%	98.12K	7.37M	73.3K	+295.29%
Mar 31, 2024	IKARIAN CAPITAL, LLC	0.17%	101.6K	7.63M	-156.54K	-60.64%
Mar 31, 2024	RAFFERTY ASSET MANAGEMENT, LLC	0.19%	108.67K	8.16M	-18.38K	-14.47%
Mar 31, 2024	CITADEL ADVISORS LLC	0.19%	109.88K	8.25M	-99.26K	-47.46%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.19%	111.92K	8.4M	-7.5K	-6.28%
Mar 31, 2024	NICHOLAS INVESTMENT PARTNERS, LP	0.21%	122.79K	9.22M	43.59K	+55.04%
Mar 31, 2024	ROCK SPRINGS CAPITAL MANAGEMENT LP	0.22%	125.3K	9.41M	125.3K	+100.00%
Mar 31, 2024	SOLEUS CAPITAL MANAGEMENT, L.P.	0.22%	129.29K	9.71M	-193.6K	-59.96%
Mar 31, 2024	CAPTION MANAGEMENT, LLC	0.23%	132K	9.91M	27K	+25.71%
Mar 31, 2024	ARROWMARK COLORADO HOLDINGS LLC	0.24%	140.96K	10.58M	-58.09K	-29.18%
Mar 31, 2024	AFFINITY ASSET ADVISORS, LLC	0.26%	150K	11.26M	-25K	-14.29%
Mar 31, 2024	SILVERARC CAPITAL MANAGEMENT, LLC	0.27%	157.75K	11.85M	-35.25K	-18.26%
Mar 31, 2024	VICTORY CAPITAL MANAGEMENT INC	0.3%	176.25K	13.23M	-8.88K	-4.79%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.31%	178.37K	13.39M	-40.26K	-18.41%
Mar 31, 2024	EAGLE ASSET MANAGEMENT INC	0.32%	183.65K	14.16M	183.65K	+100.00%
Mar 31, 2024	MORGAN STANLEY	0.32%	184.67K	13.87M	-88.45K	-32.39%
Mar 31, 2024	DIMENSIONAL FUND ADVISORS LP	0.33%	192.81K	14.48M	-91.01K	-32.07%
Mar 31, 2024	PICTET ASSET MANAGEMENT HOLDING SA	0.35%	202.36K	15.19M	8.35K	+4.31%
Mar 31, 2024	RUBRIC CAPITAL MANAGEMENT LP	0.45%	261.87K	19.66M	261.87K	+100.00%
Mar 31, 2024	FIRST TURN MANAGEMENT, LLC	0.46%	265.9K	19.97M	10K	+3.91%
Mar 31, 2024	NORTHERN TRUST CORP	0.46%	267.17K	20.06M	-13.41K	-4.78%
Mar 31, 2024	DEEP TRACK CAPITAL, LP	0.47%	274.51K	20.61M	-175.49K	-39.00%
Mar 31, 2024	CANDRIAM S.C.A.	0.49%	284.01K	21.33M	4K	+1.43%
Mar 31, 2024	LORD, ABBETT & CO. LLC	0.78%	452.19K	33.96M	-1.96K	-0.43%
Mar 31, 2024	FRED ALGER MANAGEMENT, LLC	0.94%	544.37K	40.88M	222.42K	+69.08%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.96%	557.8K	41.89M	283.8K	+103.58%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	1.17%	681.6K	51.19M	26.85K	+4.10%
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	1.47%	858.16K	64.44M	-248.22K	-22.44%
Mar 31, 2024	BOXER CAPITAL, LLC	1.92%	1.12M	84.12M	0	0
Mar 31, 2024	DARWIN GLOBAL MANAGEMENT, LTD.	2.47%	1.44M	107.9M	1.38M	+2,390.49%
Mar 31, 2024	FAIRMOUNT FUNDS MANAGEMENT LLC	3.31%	1.92M	144.52M	0	0
Mar 31, 2024	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	4.63%	2.7M	202.54M	-880K	-24.60%
Mar 31, 2024	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	34.34%	19.99M	1.5B	0	0
Mar 31, 2024	INVESCO LTD.	0.34%	195.14K	14.65M	24.54K	+14.39%
Mar 31, 2024	VOYA INVESTMENT MANAGEMENT LLC	0.39%	228.12K	17.13M	141.41K	+163.09%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.42%	242.04K	18.18M	5.16K	+2.18%
Mar 31, 2024	COMMODORE CAPITAL LP	2.56%	1.49M	111.72M	156.72K	+11.77%
Mar 31, 2024	STATE STREET CORP	2.6%	1.51M	113.69M	-187.13K	-11.00%
Mar 31, 2024	FIRST TRUST ADVISORS LP	0.03%	16.65K	1.25M	-538	-3.13%
Mar 31, 2024	DEKABANK DEUTSCHE GIROZENTRALE	0.03%	17K	1.3M	0	0
Mar 31, 2024	PROFUND ADVISORS LLC	0.03%	17.04K	1.28B	-3.66K	-17.67%
Mar 31, 2024	RENAISSANCE CAPITAL LLC	0.03%	17.33K	1.3M	17.33K	+100.00%
Mar 31, 2024	HARBOR CAPITAL ADVISORS, INC.	0.03%	18.98K	1.43M	18.98K	+100.00%
Mar 31, 2024	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.03%	19.22K	1.44M	19.22K	+100.00%
Mar 31, 2024	READYSTATE ASSET MANAGEMENT LP	0.04%	23K	1.73M	23K	+100.00%
Mar 31, 2024	STATE OF WISCONSIN INVESTMENT BOARD	0.04%	24.35K	1.83M	-1.71K	-6.57%
Mar 31, 2024	NEW YORK STATE COMMON RETIREMENT FUND	0.05%	26.83K	2.01M	4.67K	+21.08%
Mar 31, 2024	LEGAL & GENERAL GROUP PLC	0.05%	27.19K	2.04B	-997	-3.54%
Dec 31, 2023	DIMENSIONAL FUND ADVISORS LP	0.5%	283.82K	20.89M	18.26K	+6.88%
Dec 31, 2023	SOLEUS CAPITAL MANAGEMENT, L.P.	0.57%	322.89K	23.76M	168.47K	+109.10%
Dec 31, 2023	DEEP TRACK CAPITAL, LP	0.79%	450K	33.12M	450K	+100.00%
Dec 31, 2023	LORD, ABBETT & CO. LLC	0.8%	454.15K	33.42M	454.15K	+100.00%
Dec 31, 2023	D. E. SHAW & CO., INC.	0.82%	468.18K	34.45M	150.91K	+47.56%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.15%	654.75K	48.19M	109.4K	+20.06%
Dec 31, 2023	DRIEHAUS CAPITAL MANAGEMENT LLC	1.64%	937.73K	69.01M	-301.68K	-24.34%
Dec 31, 2023	WELLINGTON MANAGEMENT GROUP LLP	1.78%	1.01M	74.58M	1.01M	+100.00%
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	1.94%	1.11M	81.42M	299.45K	+37.11%
Dec 31, 2023	BOXER CAPITAL, LLC	1.96%	1.12M	82.43M	-90K	-7.44%
Dec 31, 2023	COMMODORE CAPITAL LP	2.33%	1.33M	97.95M	502.26K	+60.60%
Dec 31, 2023	STATE STREET CORP	2.98%	1.7M	125.19M	440.77K	+34.97%
Dec 31, 2023	FAIRMOUNT FUNDS MANAGEMENT LLC	3.37%	1.92M	141.63M	-527.19K	-21.50%
Dec 31, 2023	BLACKROCK INC.	4.77%	2.72M	200.25M	291.22K	+11.98%
Dec 31, 2023	PERCEPTIVE ADVISORS LLC	5.11%	2.92M	214.73M	454.54K	+18.45%
Dec 31, 2023	VANGUARD GROUP INC	5.85%	3.34M	245.78M	1.21M	+56.49%
Dec 31, 2023	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	6.27%	3.58M	263.25M	0	0
Dec 31, 2023	PARADIGM BIOCAPITAL ADVISORS LP	6.76%	3.86M	283.91M	2.22M	+135.51%
Dec 31, 2023	FMR LLC	15.28%	8.73M	642.08M	1.11M	+14.51%
Dec 31, 2023	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	35.02%	19.99M	1.47B	0	0
Dec 31, 2023	NICHOLAS INVESTMENT PARTNERS, LP	0.14%	79.2K	5.83M	-189.14K	-70.49%
Dec 31, 2023	UBS GROUP AG	0.14%	80.63K	5.93M	61.76K	+327.34%
Dec 31, 2023	JANE STREET GROUP, LLC	0.15%	84.72K	6.23M	29.85K	+54.41%
Dec 31, 2023	VOYA INVESTMENT MANAGEMENT LLC	0.15%	86.71K	6.38M	77.08K	+800.38%
Dec 31, 2023	BARCLAYS PLC	0.15%	88.11K	6.48M	36.86K	+71.94%
Dec 31, 2023	BANK OF MONTREAL /CAN/	0.16%	89.08K	6.69M	89.08K	+100.00%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.16%	90.6K	6.67M	25.88K	+39.98%
Dec 31, 2023	CAPTION MANAGEMENT, LLC	0.18%	105K	7.73M	105K	+100.00%
Dec 31, 2023	RHENMAN & PARTNERS ASSET MANAGEMENT AB	0.2%	112.93K	8.31M	26.92K	+31.30%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.21%	119.41K	8.79M	36.11K	+43.34%
Dec 31, 2023	RAFFERTY ASSET MANAGEMENT, LLC	0.22%	127.05K	9.35M	31.33K	+32.73%
Dec 31, 2023	INVESCO LTD.	0.3%	170.6K	12.55M	-38.09K	-18.25%
Dec 31, 2023	AFFINITY ASSET ADVISORS, LLC	0.31%	175K	12.88M	125K	+250.00%
Dec 31, 2023	FRANKLIN RESOURCES INC	0.31%	175.44K	12.91M	21.39K	+13.89%
Dec 31, 2023	AVORO CAPITAL ADVISORS LLC	0.31%	178.92K	13.17M	-633.58K	-77.98%
Dec 31, 2023	VICTORY CAPITAL MANAGEMENT INC	0.32%	185.12K	13.62M	-23.85K	-11.41%
Dec 31, 2023	SILVERARC CAPITAL MANAGEMENT, LLC	0.34%	193K	14.2M	193K	+100.00%
Dec 31, 2023	ARROWMARK COLORADO HOLDINGS LLC	0.35%	199.05K	14.65M	-70.71K	-26.21%
Dec 31, 2023	CITADEL ADVISORS LLC	0.37%	209.14K	15.39M	208.93K	+100,934.30%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.38%	218.63K	16.09M	138.52K	+172.93%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.41%	236.88K	17.43M	38.9K	+19.65%
Dec 31, 2023		0.34%	194K	14.28M	194K	+100.00%
Dec 31, 2023	IKARIAN CAPITAL, LLC	0.18%	104.4K	7.68M	102.01K	+4,259.08%
Dec 31, 2023	MORGAN STANLEY	0.48%	273.12K	20.1M	100.89K	+58.58%
Dec 31, 2023	CANDRIAM S.C.A.	0.49%	280.01K	20.61M	-70.01K	-20.00%
Dec 31, 2023	NORTHERN TRUST CORP	0.49%	280.57K	20.65M	33.47K	+13.54%
Dec 31, 2023	FRED ALGER MANAGEMENT, LLC	0.56%	321.95K	23.69M	241.92K	+302.25%

Insiders

Among the NUVL insiders holding of 2.84% of the stake in company, FLYNN JAMES E, Director by Deputization, holds the largest shares of 8.3M. HACK ANDREW A. F., director, is the second largest NUVL insider with ownership of 1.45M shares. PORTER JAMES RICHARD, President and CEO, stands third with possession of 278.63K shares of that stake.

Insiders	Designation	Shares Held
FLYNN JAMES E	Director by Deputization	8.3M
HACK ANDREW A. F.	director	1.45M
PORTER JAMES RICHARD	President and CEO	278.63K
SHAIR MATTHEW	director	201.67K
BALCOM ALEXANDRA	Chief Financial Officer	81.73K
PELISH HENRY E.	Chief Scientific Officer	65.89K
MILLER DEBORAH ANN	Chief Legal Officer	59.63K
NOCI DARLENE	Chief Development Officer	58.12K
TURNER CHRISTOPHER DURANT	Chief Medical Officer	55.13K
CONLEY EMILY	director	2.51K
PROTOPAPAS ANNA	director	0

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Jan 29, 2026	NOCI DARLENE	SALE	103.39	63	6.51K	58.12K
Jan 22, 2026	MILLER DEBORAH ANN	SALE	110.16	14.3K	1.58M	59.63K
Jan 21, 2026	MILLER DEBORAH ANN	SALE	109.84	700	76.89K	59.63K
Jan 06, 2026	NOCI DARLENE	SALE	98.40	225	22.14K	40.62K
Jan 06, 2026	PORTER JAMES RICHARD	SALE	98.40	675	66.42K	278.63K
Jan 06, 2026	BALCOM ALEXANDRA	SALE	98.40	225	22.14K	81.73K
Jan 06, 2026	TURNER CHRISTOPHER DURANT	SALE	98.40	225	22.14K	55.13K
Jan 06, 2026	MILLER DEBORAH ANN	SALE	98.40	183	18.01K	42.13K
Jan 06, 2026	PELISH HENRY E.	SALE	98.40	189	18.6K	65.89K
Jan 05, 2026	MILLER DEBORAH ANN	SALE	98.52	326	32.12K	44.72K
Jan 05, 2026	NOCI DARLENE	SALE	98.52	317	31.23K	43.8K
Jan 05, 2026	PELISH HENRY E.	SALE	98.52	186	18.32K	68.55K
Jan 05, 2026	PORTER JAMES RICHARD	SALE	98.52	1.34K	131.72K	288.17K
Jan 05, 2026	TURNER CHRISTOPHER DURANT	SALE	98.52	317	31.23K	58.31K
Jan 05, 2026	BALCOM ALEXANDRA	SALE	98.52	317	31.23K	84.91K
Jan 02, 2026	MILLER DEBORAH ANN	SALE	101.47	540	54.79K	49.09K
Dec 30, 2025	NOCI DARLENE	SALE	101.22	642	64.98K	48.03K
Dec 08, 2025	BALCOM ALEXANDRA	SALE	111.32	100	11.13K	54.65K
Nov 28, 2025	NOCI DARLENE	SALE	108.72	3.36K	364.76K	48.03K
Nov 24, 2025	FLYNN JAMES E	SALE	95.44	371.29K	35.44M	8.3M
Nov 24, 2025	SHAIR MATTHEW	SALE	110.42	336	37.1K	201.67K
Nov 18, 2025	BALCOM ALEXANDRA	SALE	104.54	509	53.21K	61.73K
Nov 17, 2025	BALCOM ALEXANDRA	SALE	103.68	380	39.4K	61.73K
Nov 17, 2025	MILLER DEBORAH ANN	SALE	107.04	608	65.08K	49.09K
Oct 30, 2025	MILLER DEBORAH ANN	SALE	104.78	9.38K	983.05K	49.09K
Oct 30, 2025	NOCI DARLENE	SALE	104.58	218	22.8K	48.03K
Oct 28, 2025	SHAIR MATTHEW	SALE	100.27	9.15K	917.87K	203.32K
Oct 27, 2025	SHAIR MATTHEW	SALE	100.23	4.05K	405.53K	212.48K
Oct 20, 2025	MILLER DEBORAH ANN	SALE	94.91	5K	474.55K	49.09K
Oct 16, 2025	PORTER JAMES RICHARD	SALE	92.63	700	64.84K	249.06K
Oct 16, 2025	MILLER DEBORAH ANN	SALE	92.50	4.9K	453.25K	49.09K
Oct 15, 2025	BALCOM ALEXANDRA	SALE	85.57	1.68K	144.01K	61.73K
Oct 15, 2025	MILLER DEBORAH ANN	SALE	89.98	15.62K	1.41M	49.09K
Oct 15, 2025	PELISH HENRY E.	SALE	90.04	14.21K	1.28M	65.96K
Oct 14, 2025	PELISH HENRY E.	SALE	87.39	400	34.96K	65.96K
Oct 14, 2025	BALCOM ALEXANDRA	SALE	88.90	200	17.78K	61.73K
Oct 13, 2025	PELISH HENRY E.	SALE	89.81	7.64K	685.88K	65.96K
Oct 13, 2025	BALCOM ALEXANDRA	SALE	89.22	1.6K	142.4K	61.73K
Oct 01, 2025	BALCOM ALEXANDRA	SALE	86.37	970	83.78K	61.73K
Sep 30, 2025	BALCOM ALEXANDRA	SALE	85.06	20K	1.7M	61.73K
Sep 29, 2025	NOCI DARLENE	SALE	84.92	417	35.41K	48.03K
Sep 29, 2025	BALCOM ALEXANDRA	SALE	85.01	7.59K	645.06K	61.73K
Sep 15, 2025	PORTER JAMES RICHARD	SALE	80.12	2.1K	168.01K	249.06K
Sep 10, 2025	PELISH HENRY E.	SALE	78.83	3.73K	293.64K	65.96K
Aug 25, 2025	NOCI DARLENE	SALE	75.63	109	8.24K	48.03K
Aug 15, 2025	PORTER JAMES RICHARD	SALE	76.90	100	7.69K	249.06K
Aug 07, 2025	PELISH HENRY E.	SALE	74.85	5.5K	411.68K	60.96K
Jul 30, 2025	NOCI DARLENE	SALE	80.36	4K	321.44K	48.03K
Jul 16, 2025	BALCOM ALEXANDRA	SALE	85.10	14.7K	1.25M	61.73K
Jul 15, 2025	PORTER JAMES RICHARD	SALE	84.53	104	8.79K	249.06K
Jul 15, 2025	BALCOM ALEXANDRA	SALE	85.48	54	4.62K	61.73K
Jul 10, 2025	PELISH HENRY E.	SALE	80.92	240	19.42K	60.96K
Jul 09, 2025	PELISH HENRY E.	SALE	81.90	200	16.38K	60.96K
Jun 27, 2025	PELISH HENRY E.	SALE	79.92	2.17K	173.43K	63.1K
Jun 27, 2025	BALCOM ALEXANDRA	SALE	80.02	20K	1.6M	61.73K
Jun 26, 2025	NOCI DARLENE	SALE	79.15	306	24.22K	48.03K
Jun 25, 2025	PELISH HENRY E.	SALE	79.87	8.63K	689.28K	63.1K
Jun 16, 2025	PORTER JAMES RICHARD	SALE	78.22	200	15.64K	249.06K
Jun 06, 2025	PELISH HENRY E.	SALE	79.82	200	15.96K	63.1K
May 29, 2025	NOCI DARLENE	SALE	71.67	563	40.35K	48.03K
May 15, 2025	PORTER JAMES RICHARD	SALE	70.77	335	23.71K	249.06K
Apr 29, 2025	NOCI DARLENE	SALE	74.56	4K	298.24K	48.03K
Apr 15, 2025	PORTER JAMES RICHARD	SALE	70.73	488	34.52K	249.06K
Mar 27, 2025	NOCI DARLENE	SALE	73.83	900	66.45K	48.03K
Mar 17, 2025	PORTER JAMES RICHARD	SALE	76.69	601	46.09K	249.06K
Mar 07, 2025	NOCI DARLENE	SALE	72.59	1.1K	79.85K	48.03K
Mar 06, 2025	NOCI DARLENE	SALE	72.60	4.31K	312.62K	48.03K
Feb 24, 2025	SHAIR MATTHEW	SALE	79.13	302	23.9K	216.52K
Feb 18, 2025	PORTER JAMES RICHARD	SALE	79.01	800	63.21K	249.06K
Jan 27, 2025	SHAIR MATTHEW	SALE	85.00	108	9.18K	218.52K
Jan 15, 2025	PORTER JAMES RICHARD	SALE	77.28	5.84K	451.47K	249.06K
Jan 06, 2025	NOCI DARLENE	SALE	80.54	2.17K	175.01K	48.03K
Jan 06, 2025	PORTER JAMES RICHARD	SALE	80.54	9.36K	753.85K	249.06K
Jan 06, 2025	MILLER DEBORAH ANN	SALE	80.54	1.6K	129.19K	49.09K
Jan 06, 2025	BALCOM ALEXANDRA	SALE	80.54	2.17K	175.01K	61.73K
Jan 06, 2025	PELISH HENRY E.	SALE	80.54	1.34K	108.17K	59.98K
Jan 06, 2025	TURNER CHRISTOPHER DURANT	SALE	80.54	2.17K	175.01K	62.55K
Dec 23, 2024	SHAIR MATTHEW	SALE	84.17	591	49.74K	220.52K
Dec 16, 2024	PORTER JAMES RICHARD	SALE	86.96	8.03K	698.38K	188.11K
Dec 11, 2024	HACK ANDREW A. F.	SALE	88.00	1.25M	110M	1.45M
Nov 29, 2024	BALCOM ALEXANDRA	SALE	96.25	1.86K	178.83K	33.3K
Nov 25, 2024	SHAIR MATTHEW	SALE	97.40	30	2.92K	222.52K
Nov 15, 2024	PORTER JAMES RICHARD	SALE	89.98	1.11K	99.97K	188.11K
Nov 01, 2024	NOCI DARLENE	SALE	90.03	500	45.02K	33.3K
Oct 31, 2024	BALCOM ALEXANDRA	SALE	90.94	100	9.09K	33.3K
Oct 28, 2024	SHAIR MATTHEW	SALE	93.11	73	6.8K	224.52K
Oct 22, 2024	FLYNN JAMES E	SALE	97.75	1M	97.75M	8.67M
Oct 15, 2024	PORTER JAMES RICHARD	SALE	103.01	814	83.85K	188.11K
Oct 01, 2024	NOCI DARLENE	SALE	104.69	174	18.22K	33.3K
Sep 30, 2024	BALCOM ALEXANDRA	SALE	101.89	2.96K	301.9K	33.3K
Sep 23, 2024	SHAIR MATTHEW	SALE	107.82	23	2.48K	226.52K
Sep 16, 2024	PELISH HENRY E.	SALE	94.80	3.75K	355.88K	60.38K
Sep 16, 2024	MILLER DEBORAH ANN	SALE	102.00	300	30.6K	33.3K
Sep 09, 2024	MILLER DEBORAH ANN	SALE	89.11	161	14.35K	33.3K
Sep 03, 2024	NOCI DARLENE	SALE	85.64	512	43.85K	33.3K
Aug 30, 2024	BALCOM ALEXANDRA	SALE	85.96	288	24.76K	33.3K
Aug 26, 2024	SHAIR MATTHEW	SALE	85.53	156	13.34K	228.52K
Aug 23, 2024	PELISH HENRY E.	SALE	85.08	10.5K	893.34K	66.1K
Aug 23, 2024	CONLEY EMILY	SALE	85.02	3.33K	283.46K	2.51K
Aug 23, 2024	MILLER DEBORAH ANN	SALE	85.04	11K	935.44K	33.3K
Aug 08, 2024	MILLER DEBORAH ANN	SALE	69.95	374	26.16K	33.3K
Aug 01, 2024	NOCI DARLENE	SALE	80.32	63	5.06K	33.3K
Jul 31, 2024	BALCOM ALEXANDRA	SALE	81.31	1.14K	92.29K	33.3K
Jul 29, 2024	SHAIR MATTHEW	SALE	81.71	91	7.44K	230.52K
Jul 15, 2024	CONLEY EMILY	SALE	81.93	205	16.8K	2.51K
Jul 12, 2024	MILLER DEBORAH ANN	SALE	80.16	6K	480.96K	33.3K
Jul 08, 2024	MILLER DEBORAH ANN	SALE	73.84	699	51.61K	33.3K
Jul 01, 2024	NOCI DARLENE	SALE	76.19	542	41.29K	33.3K
Jun 28, 2024	BALCOM ALEXANDRA	SALE	76.73	572	43.89K	33.3K
Jun 24, 2024	SHAIR MATTHEW	SALE	80.98	190	15.39K	232.52K
Jun 14, 2024	CONLEY EMILY	SALE	78.31	223	17.46K	2.51K
Jun 06, 2024	MILLER DEBORAH ANN	SALE	82.33	1.57K	128.93K	33.3K
May 28, 2024	SHAIR MATTHEW	SALE	68.64	16	1.1K	234.52K
May 15, 2024	CONLEY EMILY	SALE	69.09	5K	345.45K	8
May 13, 2024	SHAIR MATTHEW	SALE	66.86	4.46K	298.33K	1.42M
May 06, 2024	SHAIR MATTHEW	SALE	70.27	7.9K	555.13K	1.46M
May 02, 2024	MILLER DEBORAH ANN	SALE	73.13	138	10.09K	33.3K
Apr 29, 2024	SHAIR MATTHEW	SALE	68.57	85	5.83K	236.52K
Apr 22, 2024	SHAIR MATTHEW	SALE	64.52	14.65K	945.22K	1.54M
Apr 15, 2024	SHAIR MATTHEW	SALE	66.17	11.9K	787.42K	1.57M
Apr 15, 2024	CONLEY EMILY	SALE	66.66	6	399.96	8
Apr 08, 2024	SHAIR MATTHEW	SALE	69.64	1K	69.64K	1.61M
Apr 04, 2024	MILLER DEBORAH ANN	SALE	74.81	1.49K	111.54K	33.3K
Apr 01, 2024	SHAIR MATTHEW	SALE	77.19	9.69K	748.28K	1.65M
Mar 28, 2024	MILLER DEBORAH ANN	SALE	75.94	3.04K	231.16K	33.3K
Mar 27, 2024	HACK ANDREW A. F.	SALE	72.31	791.8K	57.25M	2.7M
Mar 25, 2024	SHAIR MATTHEW	SALE	77.37	105	8.12K	238.52K
Mar 22, 2024	NOCI DARLENE	SALE	78.72	600	47.23K	33.3K
Mar 15, 2024	CONLEY EMILY	SALE	84.44	1K	84.44K	8
Dec 28, 2023	SHAIR MATTHEW	SALE	76.14	13.49K	1.03M	1.72M
Dec 27, 2023	SHAIR MATTHEW	SALE	75.17	1K	75.17K	1.77M
Dec 26, 2023	SHAIR MATTHEW	SALE	75.13	68.67K	5.16M	1.77M
Dec 19, 2023	MILLER DEBORAH ANN	SALE	75.00	5K	375K	0
Dec 18, 2023	BALCOM ALEXANDRA	SALE	75.82	30K	2.27M	0
Dec 18, 2023	PROTOPAPAS ANNA	SALE	75.67	5K	378.35K	0
Dec 18, 2023	MILLER DEBORAH ANN	SALE	75.82	33.05K	2.51M	0
Dec 18, 2023	NOCI DARLENE	SALE	75.82	40K	3.03M	0
Nov 28, 2023	SHAIR MATTHEW	SALE	62.37	2.8K	174.51K	1.84M
Nov 01, 2023	NOCI DARLENE	SALE	53.11	976	51.84K	0
Oct 24, 2023	SHAIR MATTHEW	SALE	51.23	10.17K	520.96K	1.85M
Oct 04, 2023	TURNER CHRISTOPHER DURANT	SALE	57.18	500	28.59K	15.98K
Oct 04, 2023	NOCI DARLENE	SALE	57.54	5.4K	310.72K	0
Oct 02, 2023	NOCI DARLENE	SALE	46.01	2.14K	98.65K	111
Sep 15, 2023	MILLER DEBORAH ANN	SALE	47.99	756	36.28K	0
Sep 01, 2023	NOCI DARLENE	SALE	46.86	1.8K	84.35K	0
Aug 15, 2023	MILLER DEBORAH ANN	SALE	43.01	709	30.49K	0
Aug 01, 2023	NOCI DARLENE	SALE	49.69	964	47.9K	2.04K
Jul 31, 2023	BALCOM ALEXANDRA	SALE	49.49	10.85K	536.87K	0
Jul 28, 2023	MILLER DEBORAH ANN	SALE	48.52	6.5K	315.38K	0
Jul 28, 2023	TURNER CHRISTOPHER DURANT	SALE	48.93	2.67K	130.4K	14.51K
Jul 26, 2023	TURNER CHRISTOPHER DURANT	SALE	46.85	2.37K	110.8K	14.51K
Jul 24, 2023	TURNER CHRISTOPHER DURANT	SALE	46.82	200	9.36K	14.51K
Jul 20, 2023	NOCI DARLENE	SALE	45.17	10.94K	494.2K	0
Jul 20, 2023	TURNER CHRISTOPHER DURANT	SALE	46.80	100	4.68K	14.51K
Jul 19, 2023	NOCI DARLENE	SALE	45.04	4.56K	205.34K	0
Jul 17, 2023	MILLER DEBORAH ANN	SALE	43.93	298	13.09K	0
Jul 03, 2023	NOCI DARLENE	SALE	42.12	553	23.29K	0
Jun 16, 2023	NOCI DARLENE	SALE	45.19	2.9K	131.05K	0
Jun 15, 2023	MILLER DEBORAH ANN	SALE	44.86	164	7.36K	0
Jun 15, 2023	NOCI DARLENE	SALE	45.07	1K	45.07K	0
Jun 05, 2023	TURNER CHRISTOPHER DURANT	SALE	44.86	10.24K	459.14K	14.51K
Jun 05, 2023	NOCI DARLENE	SALE	45.00	600	27K	0
Jun 01, 2023	NOCI DARLENE	SALE	41.46	239	9.91K	2.76K
May 15, 2023	MILLER DEBORAH ANN	SALE	40.31	502	20.24K	1.5K
May 09, 2023	MILLER DEBORAH ANN	SALE	39.63	1.33K	52.79K	0
May 05, 2023	MILLER DEBORAH ANN	SALE	39.64	2.8K	110.99K	0
May 01, 2023	NOCI DARLENE	SALE	35.71	28	999.88	2.97K
May 01, 2023	MILLER DEBORAH ANN	SALE	39.61	900	35.65K	0
Apr 17, 2023	MILLER DEBORAH ANN	SALE	29.33	125	3.67K	1.88K
Apr 03, 2023	NOCI DARLENE	SALE	26.57	2.89K	76.73K	112
Mar 15, 2023	MILLER DEBORAH ANN	SALE	28.17	1.84K	51.8K	161
Mar 01, 2023	NOCI DARLENE	SALE	29.81	2.6K	77.51K	400
Feb 15, 2023	MILLER DEBORAH ANN	SALE	29.51	1.84K	54.36K	158
Feb 02, 2023	NOCI DARLENE	SALE	29.37	1.99K	58.39K	1.01K
Jan 17, 2023	MILLER DEBORAH ANN	SALE	32.15	709	22.79K	1.29K
Jan 04, 2023	SHAIR MATTHEW	SALE	27.92	16.02K	447.17K	1.95M
Dec 15, 2022	NOCI DARLENE	SALE	29.53	3.4K	100.4K	800
Dec 15, 2022	MILLER DEBORAH ANN	SALE	29.47	1.32K	39.02K	676
Dec 07, 2022	SHAIR MATTHEW	SALE	30.98	12.71K	393.63K	1.97M
Nov 15, 2022	MILLER DEBORAH ANN	SALE	31.24	600	18.74K	1.4K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES506.88K44

NET SHARES-506.88K44

SHARES HELD12.04M44

% NET SHARES-104.21%0%

Frequently Asked Questions

Stock Outstanding Shares

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares7.69

Short Percent Of Float17.88

Shares Outstanding66.67M

Shares Float41.56M

Shares Short5.54M

Short Ratio11.1

17.88%

Short % of Float

7.69%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

2.84% Percentage of Shares held by All Insiders

109.13% Percentage of Shares held by All Institutions

112.31% Percentage of Float held by Institutions

298

Number of Institutions Holding Shares

Institutional Ownership

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Dec 31, 2025	FMR LLC	15.04%	10.85M	1.09B	839.65K	+8.39%
Dec 31, 2025		0.37%	269.04K	27.06B	269.04K	+100.00%
Dec 31, 2025	FIRST TURN MANAGEMENT, LLC	0.51%	368.7K	37.09M	-26.06K	-6.60%
Dec 31, 2025	AMERICAN CENTURY COMPANIES INC	0.52%	374.23K	37.64M	11.3K	+3.11%
Dec 31, 2025	UBS GROUP AG	0.55%	399.05K	40.14M	185.93K	+87.24%
Dec 31, 2025	FRANKLIN RESOURCES INC	0.57%	411.35K	41.38M	251.22K	+156.88%
Dec 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.63%	453.31K	45.6M	48.76K	+12.05%
Dec 31, 2025	NORGES BANK	0.8%	574.24K	57.76M	574.24K	+100.00%
Dec 31, 2025	GOLDMAN SACHS GROUP INC	0.82%	594.46K	59.8M	150.02K	+33.76%
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.72%	1.24M	124.58M	144.24K	+13.18%
Dec 31, 2025	STATE STREET CORP	2.58%	1.86M	187.57M	289.93K	+18.41%
Dec 31, 2025	JPMORGAN CHASE & CO	3.06%	2.21M	221.83M	531.24K	+31.73%
Dec 31, 2025	BLACKROCK, INC.	6.66%	4.81M	483.36M	719.47K	+17.61%
Dec 31, 2025	VANGUARD GROUP INC	7.27%	5.24M	527.52M	639.26K	+13.88%
Dec 31, 2025	FRONTIER CAPITAL MANAGEMENT CO LLC	0.37%	270.47K	27.21M	270.47K	+100.00%
Dec 31, 2025	ARROWMARK COLORADO HOLDINGS LLC	0.41%	296.03K	29.78M	-66.56K	-18.36%
Dec 31, 2025	NORTHERN TRUST CORP	0.57%	410.45K	41.29M	28.95K	+7.59%
Dec 31, 2025	INVESCO LTD.	0.61%	439.3K	44.19M	405.54K	+1,201.36%
Dec 31, 2025	HOOD RIVER CAPITAL MANAGEMENT LLC	0.66%	475.44K	47.82M	475.44K	+100.00%
Dec 31, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	0.67%	483.5K	48.64M	266.95K	+123.27%
Dec 31, 2025	FAIRMOUNT FUNDS MANAGEMENT LLC	1.01%	727.56K	73.19M	0	0
Dec 31, 2025	ALLIANCEBERNSTEIN L.P.	1.09%	785.45K	79.01M	735.48K	+1,471.90%
Dec 31, 2025	BRAIDWELL LP	1.14%	821.41K	82.63M	-191.58K	-18.91%
Dec 31, 2025	BELLEVUE GROUP AG	1.44%	1.04M	104.36M	1.04M	+100.00%
Dec 31, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	1.83%	1.32M	132.78M	298.73K	+29.25%
Dec 31, 2025	JANUS HENDERSON GROUP PLC	2.08%	1.5M	150.82M	-689.1K	-31.48%
Dec 31, 2025	POLAR CAPITAL HOLDINGS PLC	2.13%	1.54M	154.59M	514.63K	+50.34%
Dec 31, 2025	PERCEPTIVE ADVISORS LLC	2.31%	1.67M	167.49M	102.77K	+6.58%
Dec 31, 2025	COMMODORE CAPITAL LP	0.76%	550K	55.32M	-850K	-60.71%
Dec 31, 2025	AMERIPRISE FINANCIAL INC	0.78%	564.3K	56.76M	37.25K	+7.07%
Dec 31, 2025	RA CAPITAL MANAGEMENT, L.P.	2.61%	1.88M	189.11M	633.6K	+50.83%
Dec 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	2.98%	2.15M	215.96M	336.52K	+18.59%
Dec 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	3.41%	2.46M	247.63M	160.96K	+7.00%
Dec 31, 2025	PARADIGM BIOCAPITAL ADVISORS LP	7.3%	5.27M	530.05M	0	0
Dec 31, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	23.91%	17.25M	1.74B	-742.57K	-4.13%
Dec 31, 2025	MARSHALL WACE, LLP	0.03%	23.93K	2.41M	23.93K	+100.00%
Dec 31, 2025	SEVEN GRAND MANAGERS, LLC	0.03%	25K	2.51M	25K	+100.00%
Dec 31, 2025	ALYESKA INVESTMENT GROUP, L.P.	0.04%	25.53K	2.57M	-75.53K	-74.74%
Dec 31, 2025	RHENMAN & PARTNERS ASSET MANAGEMENT AB	0.23%	163.35K	16.43M	110.85K	+211.14%
Dec 31, 2025	ABRDN PLC	0.23%	165.18K	16.62M	88.49K	+115.39%
Dec 31, 2025	CITADEL ADVISORS LLC	0.27%	195.16K	19.63M	164.93K	+545.66%
Dec 31, 2025	MORGAN STANLEY	0.37%	267.39K	26.9M	-7.72K	-2.81%
Dec 31, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.04%	27.63K	2.78M	2.54K	+10.14%
Dec 31, 2025	LORD, ABBETT & CO. LLC	0.39%	281.22K	28.29M	281.22K	+100.00%
Dec 31, 2025	TRI LOCUM PARTNERS LP	0.43%	307.37K	30.92M	307.37K	+100.00%
Dec 31, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.89%	643K	64.68M	68.5K	+11.92%
Dec 31, 2025	TEMA ETFS LLC	0.05%	36.46K	3.67M	3.45K	+10.46%
Dec 31, 2025	LEGAL & GENERAL GROUP PLC	0.06%	41.65K	4.19M	-1.63K	-3.77%
Dec 31, 2025	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.06%	42.36K	4.26M	18.57K	+78.08%
Dec 31, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.06%	45.95K	4.62M	-2.04K	-4.24%
Dec 31, 2025	UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH	0.06%	46.69K	4.7M	13.61K	+41.13%
Dec 31, 2025	ENSIGN PEAK ADVISORS, INC	0.08%	54.2K	5.45M	-10.18K	-15.81%
Dec 31, 2025	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	0.08%	61.13K	6.15M	60.82K	+19,555.95%
Dec 31, 2025	SQUAREPOINT OPS LLC	0.09%	61.75K	6.21M	54.32K	+731.60%
Dec 31, 2025	JUMP FINANCIAL, LLC	0.04%	27.96K	2.81M	24.44K	+695.08%
Dec 31, 2025	WOODLINE PARTNERS LP	0.85%	610.46K	61.41M	-459.06K	-42.92%
Dec 31, 2025	WELLS FARGO & COMPANY/MN	0.09%	62.16K	6.25M	31.28K	+101.33%
Dec 31, 2025	RHUMBLINE ADVISERS	0.09%	63.84K	6.42B	-1.38K	-2.11%
Dec 31, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.11%	78.28K	7.86M	13.81K	+21.43%
Dec 31, 2025	SWISS NATIONAL BANK	0.11%	78.9K	7.94M	1.7K	+2.20%
Dec 31, 2025	MILLENNIUM MANAGEMENT LLC	0.11%	81.87K	8.23M	81.87K	+100.00%
Dec 31, 2025	DEUTSCHE BANK AG\	0.12%	83.04K	8.35M	11.34K	+15.81%
Dec 31, 2025	FISHER ASSET MANAGEMENT, LLC	0.14%	100.71K	10.13M	-5.72K	-5.37%
Dec 31, 2025	NUVEEN, LLC	0.15%	107.62K	10.83M	15.99K	+17.45%
Dec 31, 2025	PARKMAN HEALTHCARE PARTNERS LLC	0.16%	118.71K	11.94M	-1.48K	-1.23%
Dec 31, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.17%	124.56K	12.53M	59.14K	+90.40%
Dec 31, 2025	BARCLAYS PLC	0.17%	125.33K	12.61M	-1.55K	-1.22%
Dec 31, 2025	RAYMOND JAMES FINANCIAL INC	0.21%	151.97K	15.26M	20.94K	+15.98%
Dec 31, 2025	TD ASSET MANAGEMENT INC	0.21%	153.36K	15.43M	43.78K	+39.95%
Dec 31, 2025	NICHOLAS INVESTMENT PARTNERS, LP	0.22%	160.48K	16.14M	36.31K	+29.24%
Dec 31, 2025	BANK OF NEW YORK MELLON CORP	0.22%	161.6K	16.26M	16.2K	+11.14%
Dec 31, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.24%	172.53K	17.35M	37.79K	+28.04%
Dec 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.24%	174.07K	17.51M	36.12K	+26.19%
Dec 31, 2025	BANK OF AMERICA CORP /DE/	0.25%	180.37K	18.14M	19.18K	+11.90%
Dec 31, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.43%	311.43K	31.33M	-60.87K	-16.35%
Dec 31, 2025	AFFINITY ASSET ADVISORS, LLC	0.45%	322.63K	32.45M	-61.78K	-16.07%
Dec 31, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.49%	355.68K	35.78M	-28.9K	-7.51%
Dec 31, 2025	CANDRIAM S.C.A.	0.5%	358.01K	36.01M	28.29K	+8.58%
Dec 31, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.05%	32.46K	3.27M	4.4K	+15.67%
Dec 31, 2025	CITIGROUP INC	0.05%	35.83K	3.6M	671	+1.91%
Dec 31, 2025	VERITION FUND MANAGEMENT LLC	0.1%	72.02K	7.24M	66.31K	+1,162.98%
Sep 30, 2025	RHUMBLINE ADVISERS	0.09%	65.21K	5.64M	-817	-1.24%
Sep 30, 2025	DEUTSCHE BANK AG\	0.1%	71.7K	6.2M	41.73K	+139.27%
Sep 30, 2025	ABRDN PLC	0.11%	76.69K	6.63M	0	0
Sep 30, 2025	NORTHERN TRUST CORP	0.53%	381.5K	32.99M	39.72K	+11.62%
Sep 30, 2025	TD ASSET MANAGEMENT INC	0.15%	109.58K	9.48M	10.68K	+10.80%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.22%	161.19K	13.94M	-96.75K	-37.51%
Sep 30, 2025	UBS GROUP AG	0.3%	213.12K	18.43M	76.38K	+55.85%
Sep 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.54%	384.58K	33.26M	-205.26K	-34.80%
Sep 30, 2025	STATE STREET CORP	2.19%	1.57M	136.18M	84.47K	+5.67%
Sep 30, 2025	FRANKLIN RESOURCES INC	0.22%	160.13K	13.85M	504	+0.32%
Sep 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0.13%	92.48K	8M	10.88K	+13.33%
Sep 30, 2025	MORGAN STANLEY	0.38%	275.11K	23.79M	-147.61K	-34.92%
Sep 30, 2025	CANDRIAM S.C.A.	0.46%	329.72K	28.51M	28.46K	+9.45%
Sep 30, 2025	ARROWMARK COLORADO HOLDINGS LLC	0.5%	362.59K	31.36M	-7.27K	-1.97%
Sep 30, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	0.3%	216.56K	18.73M	134	+0.06%
Sep 30, 2025	BAKER BROS. ADVISORS LP	0.2%	143.94K	12.45M	0	0
Sep 30, 2025	AMERICAN CENTURY COMPANIES INC	0.51%	362.93K	31.39M	-11.77K	-3.14%
Sep 30, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.52%	372.3K	32.2M	136.72K	+58.03%
Sep 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.54%	384.42K	33.24M	-30.58K	-7.37%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.56%	404.55K	34.99M	58.05K	+16.75%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	0.62%	444.44K	38.43M	-91.01K	-17.00%
Sep 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.8%	574.5K	49.68M	-3K	-0.52%
Sep 30, 2025	FAIRMOUNT FUNDS MANAGEMENT LLC	1.01%	727.56K	62.92M	0	0
Sep 30, 2025	BRAIDWELL LP	1.41%	1.01M	87.6M	-162.89K	-13.85%
Sep 30, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	1.42%	1.02M	88.32M	-73.33K	-6.70%
Sep 30, 2025	POLAR CAPITAL HOLDINGS PLC	1.42%	1.02M	88.4M	206.14K	+25.26%
Sep 30, 2025	WOODLINE PARTNERS LP	1.49%	1.07M	92.49M	165.29K	+18.28%
Sep 30, 2025	COMMODORE CAPITAL LP	1.95%	1.4M	121.07M	25K	+1.82%
Sep 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	2.52%	1.81M	156.57M	15.05K	+0.84%
Sep 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	3.2%	2.3M	198.98M	724.49K	+45.96%
Sep 30, 2025	PARADIGM BIOCAPITAL ADVISORS LP	7.33%	5.27M	455.7M	0	0
Sep 30, 2025	HIGHVISTA STRATEGIES LLC	0.13%	93.29K	8.07M	42.83K	+84.89%
Sep 30, 2025	ALYESKA INVESTMENT GROUP, L.P.	0.14%	101.07K	8.74M	51.07K	+102.13%
Sep 30, 2025	FISHER ASSET MANAGEMENT, LLC	0.15%	106.42K	9.2M	-8.34K	-7.26%
Sep 30, 2025	PARKMAN HEALTHCARE PARTNERS LLC	0.17%	120.19K	10.39M	567	+0.47%
Sep 30, 2025	NICHOLAS INVESTMENT PARTNERS, LP	0.17%	124.18K	10.74M	20.46K	+19.72%
Sep 30, 2025	BARCLAYS PLC	0.18%	126.88K	10.97M	-22.73K	-15.19%
Sep 30, 2025	AMERIPRISE FINANCIAL INC	0.73%	527.05K	45.58M	42.71K	+8.82%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.52%	1.09M	94.62M	97.15K	+9.75%
Sep 30, 2025	RA CAPITAL MANAGEMENT, L.P.	1.74%	1.25M	107.79M	1.25M	+100.00%
Sep 30, 2025	PERCEPTIVE ADVISORS LLC	2.17%	1.56M	135.11M	187.16K	+13.61%
Sep 30, 2025	JPMORGAN CHASE & CO	2.33%	1.67M	144.77M	476.82K	+39.83%
Sep 30, 2025	VESTAL POINT CAPITAL, LP	1.53%	1.1M	95.13M	25K	+2.33%
Sep 30, 2025	JANUS HENDERSON GROUP PLC	3.05%	2.19M	189.34M	406.09K	+22.78%
Sep 30, 2025	BLACKROCK, INC.	5.69%	4.09M	353.34M	39.54K	+0.98%
Sep 30, 2025	VANGUARD GROUP INC	6.41%	4.61M	398.24M	80.88K	+1.79%
Sep 30, 2025	FMR LLC	13.94%	10.01M	865.94M	44.39K	+0.45%
Sep 30, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	25.04%	17.99M	1.56B	0	0
Sep 30, 2025	RAYMOND JAMES FINANCIAL INC	0.18%	131.03K	11.33M	-7.94K	-5.71%
Sep 30, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.19%	134.74K	11.65M	11.52K	+9.35%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.19%	137.95K	11.93M	2.33K	+1.72%
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.2%	145.4K	12.57M	2.03K	+1.42%
Sep 30, 2025	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0.02%	11.89K	1.03M	2.07K	+21.10%
Sep 30, 2025	LEGATO CAPITAL MANAGEMENT LLC	0.02%	12.65K	1.09M	3.78K	+42.61%
Sep 30, 2025	GUGGENHEIM CAPITAL LLC	0.02%	12.84K	1.11M	1.98K	+18.19%
Sep 30, 2025	HANDELSBANKEN FONDER AB	0.02%	13.9K	1.2M	1.9K	+15.83%
Sep 30, 2025	FIRST TURN MANAGEMENT, LLC	0.55%	394.75K	34.14M	73.96K	+23.05%
Sep 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.02%	14.95K	1.29M	-7.93K	-34.66%
Sep 30, 2025	HUDSON BAY CAPITAL MANAGEMENT LP	0.02%	15K	1.3M	15K	+100.00%
Sep 30, 2025	DEKABANK DEUTSCHE GIROZENTRALE	0.02%	17K	1.4M	0	0
Sep 30, 2025	SG AMERICAS SECURITIES, LLC	0.03%	18.84K	1.63M	18.84K	+100.00%
Sep 30, 2025	BRIDGEWATER ASSOCIATES, LP	0.03%	22.06K	1.91M	22.06K	+100.00%
Sep 30, 2025	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.03%	23.79K	2.06B	23.79K	+100.00%
Sep 30, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.03%	25.09K	2.17M	-619	-2.41%
Sep 30, 2025	JEFFERIES FINANCIAL GROUP INC.	0.04%	25.16K	2.18M	25.16K	+100.00%
Sep 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.04%	28.06K	2.43M	4.33K	+18.23%
Sep 30, 2025	NUVEEN, LLC	0.13%	91.63K	7.92M	-1.14K	-1.23%
Sep 30, 2025	FRED ALGER MANAGEMENT, LLC	0.12%	88.5K	7.65M	-2.94K	-3.21%
Sep 30, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	0.12%	88K	7.61M	-37K	-29.60%
Sep 30, 2025	SWISS NATIONAL BANK	0.11%	77.2K	6.68M	1.4K	+1.85%
Sep 30, 2025	STATE OF NEW JERSEY COMMON PENSION FUND D	0.04%	28.88K	2.5M	3.16K	+12.29%
Sep 30, 2025	DIMENSIONAL FUND ADVISORS LP	0.04%	29.53K	2.55M	7.16K	+32.03%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0.04%	30.87K	2.67M	-12.1K	-28.16%
Sep 30, 2025	ALPS ADVISORS INC	0.04%	30.89K	2.67M	-4.9K	-13.68%
Sep 30, 2025	TEMA ETFS LLC	0.05%	33.01K	2.85M	1.25K	+3.92%
Sep 30, 2025	NEOS INVESTMENT MANAGEMENT LLC	0.05%	33.01K	2.85M	1.25K	+3.92%
Sep 30, 2025	UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH	0.05%	33.08K	2.86M	2.52K	+8.23%
Sep 30, 2025	INVESCO LTD.	0.05%	33.76K	2.92M	-4.28K	-11.25%
Sep 30, 2025	CITIGROUP INC	0.05%	35.16K	3.04M	-104.03K	-74.74%
Sep 30, 2025	LEGAL & GENERAL GROUP PLC	0.06%	43.28K	3.74M	-1.55K	-3.47%
Sep 30, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.07%	47.98K	4.15M	-402	-0.83%
Sep 30, 2025	RHENMAN & PARTNERS ASSET MANAGEMENT AB	0.07%	52.5K	4.54M	0	0
Sep 30, 2025	ENSIGN PEAK ADVISORS, INC	0.09%	64.38K	5.57M	-30.46K	-32.12%
Jun 30, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	0.17%	125K	9.54M	-89.36K	-41.69%
Jun 30, 2025	COMMODORE CAPITAL LP	1.91%	1.38M	104.91M	-480K	-25.88%
Jun 30, 2025	JPMORGAN CHASE & CO	1.67%	1.2M	91.35M	1.1M	+1,073.82%
Jun 30, 2025	PERCEPTIVE ADVISORS LLC	1.91%	1.38M	104.93M	-258.79K	-15.84%
Jun 30, 2025	FMR LLC	13.88%	9.97M	760.62M	31.65K	+0.32%
Jun 30, 2025	VANGUARD GROUP INC	6.3%	4.52M	345.19M	84.29K	+1.90%
Jun 30, 2025	PARADIGM BIOCAPITAL ADVISORS LP	7.33%	5.27M	402.06M	0	0
Jun 30, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	1.52%	1.09M	83.52M	643.79K	+142.82%
Jun 30, 2025	VESTAL POINT CAPITAL, LP	1.5%	1.08M	82.02M	0	0
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.39%	996.85K	76.07M	103.39K	+11.57%
Jun 30, 2025	WOODLINE PARTNERS LP	1.26%	904.23K	68.99M	-301.3K	-24.99%
Jun 30, 2025	POLAR CAPITAL HOLDINGS PLC	1.14%	816.09K	62.27M	-130.64K	-13.80%
Jun 30, 2025	FAIRMOUNT FUNDS MANAGEMENT LLC	1.01%	727.56K	55.51M	0	0
Jun 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.82%	589.83K	45M	35.69K	+6.44%
Jun 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.8%	577.5K	44.06M	180.5K	+45.47%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.75%	535.45K	40.85M	81.83K	+18.04%
Jun 30, 2025	MORGAN STANLEY	0.59%	422.72K	32.25M	74.64K	+21.44%
Jun 30, 2025	NORTHERN TRUST CORP	0.48%	341.77K	26.08M	13.44K	+4.09%
Jun 30, 2025	FIRST TURN MANAGEMENT, LLC	0.45%	320.8K	24.48M	-11.13K	-3.35%
Jun 30, 2025	CANDRIAM S.C.A.	0.42%	301.26K	22.99M	-52.87K	-14.93%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0.36%	257.94K	19.68M	37.92K	+17.24%
Jun 30, 2025	FRANKLIN RESOURCES INC	0.22%	159.63K	12.18M	0	0
Jun 30, 2025	D. E. SHAW & CO., INC.	0.22%	156.79K	11.96M	25.83K	+19.72%
Jun 30, 2025	FARALLON CAPITAL MANAGEMENT LLC	0.21%	150K	11.45M	0	0
Jun 30, 2025	BARCLAYS PLC	0.21%	149.61K	11.42M	53.57K	+55.78%
Jun 30, 2025	BANK OF NEW YORK MELLON CORP	0.2%	143.38K	10.94M	28.55K	+24.86%
Jun 30, 2025	CITIGROUP INC	0.19%	139.19K	10.62M	-97.7K	-41.24%
Jun 30, 2025	RAYMOND JAMES FINANCIAL INC	0.19%	138.97K	10.6M	5.88K	+4.41%
Jun 30, 2025	UBS GROUP AG	0.19%	136.74K	10.43M	27.27K	+24.90%
Jun 30, 2025	BLACKROCK, INC.	5.63%	4.05M	308.73M	297.9K	+7.95%
Jun 30, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.17%	123.22K	9.4M	2.91K	+2.42%
Jun 30, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.33%	235.58K	17.97M	-203.44K	-46.34%
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	2.5%	1.8M	136.99M	344.77K	+23.77%
Jun 30, 2025	JANUS HENDERSON GROUP PLC	2.48%	1.78M	136.05M	472.39K	+36.05%
Jun 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	2.19%	1.58M	120.28M	133.99K	+9.29%
Jun 30, 2025	AMERIPRISE FINANCIAL INC	0.67%	484.34K	36.96M	204K	+72.77%
Jun 30, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	0.3%	216.42K	16.51M	-314.79K	-59.26%
Jun 30, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.24%	169.54K	12.94M	19.6K	+13.07%
Jun 30, 2025	STATE STREET CORP	2.07%	1.49M	113.71M	59.62K	+4.17%
Jun 30, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	2.01%	1.45M	110.43M	0	0
Jun 30, 2025	BRAIDWELL LP	1.64%	1.18M	89.72M	334.93K	+39.83%
Jun 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.58%	415K	31.66M	-45K	-9.78%
Jun 30, 2025	AMERICAN CENTURY COMPANIES INC	0.52%	374.7K	28.59M	92.65K	+32.85%
Jun 30, 2025	NORGES BANK	0.52%	374.6K	28.58M	374.6K	+100.00%
Jun 30, 2025	ARROWMARK COLORADO HOLDINGS LLC	0.51%	369.86K	28.22M	78.75K	+27.05%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.48%	346.51K	26.44M	28.74K	+9.05%
Jun 30, 2025	BAKER BROS. ADVISORS LP	0.2%	143.94K	10.98M	143.94K	+100.00%
Jun 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.19%	135.61K	10.35M	76.83K	+130.72%
Jun 30, 2025	PARKMAN HEALTHCARE PARTNERS LLC	0.17%	119.62K	9.13M	9.64K	+8.76%
Jun 30, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	25.04%	17.99M	1.37B	0	0
Mar 31, 2025	LORD, ABBETT & CO. LLC	0.26%	184.97K	13.12M	-112.62K	-37.84%
Mar 31, 2025	FRED ALGER MANAGEMENT, LLC	0.26%	187.9K	13.33M	-120.16K	-39.00%
Mar 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	2.03%	1.45M	102.88M	152.69K	+11.76%
Mar 31, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	2.02%	1.45M	102.64M	0	0
Mar 31, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.77%	554.14K	39.3M	-87.64K	-13.66%
Mar 31, 2025	MORGAN STANLEY	0.49%	348.08K	24.69M	125.8K	+56.59%
Mar 31, 2025	NORTHERN TRUST CORP	0.46%	328.33K	23.29M	-7.22K	-2.15%
Mar 31, 2025	ARROWMARK COLORADO HOLDINGS LLC	0.41%	291.1K	20.65M	-4.25K	-1.44%
Mar 31, 2025	AMERICAN CENTURY COMPANIES INC	0.39%	282.05K	20M	95.66K	+51.32%
Mar 31, 2025	AMERIPRISE FINANCIAL INC	0.39%	280.34K	19.88M	42.79K	+18.01%
Mar 31, 2025	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.35%	247.05K	17.52M	76.2K	+44.60%
Mar 31, 2025	CITIGROUP INC	0.33%	236.89K	16.8M	112.52K	+90.47%
Mar 31, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	0.3%	214.36K	15.2M	110K	+105.41%
Mar 31, 2025	POLAR CAPITAL HOLDINGS PLC	1.32%	946.72K	67.14M	0	0
Mar 31, 2025	JANE STREET GROUP, LLC	0.27%	191.3K	13.57M	43K	+29.00%
Mar 31, 2025	STEMPOINT CAPITAL LP	0.27%	190.4K	13.5M	45.17K	+31.10%
Mar 31, 2025	FIRST TURN MANAGEMENT, LLC	0.46%	331.93K	23.54M	22.41K	+7.24%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.63%	453.62K	32.17M	159.87K	+54.43%
Mar 31, 2025	AFFINITY ASSET ADVISORS, LLC	0.64%	460K	32.62M	175K	+61.40%
Mar 31, 2025	PERCEPTIVE ADVISORS LLC	2.28%	1.63M	115.88M	-986.01K	-37.63%
Mar 31, 2025	COMMODORE CAPITAL LP	2.59%	1.86M	131.56M	233.4K	+14.39%
Mar 31, 2025	BLACKROCK, INC.	5.23%	3.75M	265.83M	-103.22K	-2.68%
Mar 31, 2025	TWO SIGMA INVESTMENTS, LP	0.22%	159.12K	11.29M	-54.76K	-25.60%
Mar 31, 2025	VANGUARD GROUP INC	6.2%	4.44M	314.87M	-60.03K	-1.33%
Mar 31, 2025	PARADIGM BIOCAPITAL ADVISORS LP	7.36%	5.27M	373.71M	-93.95K	-1.75%
Mar 31, 2025	FMR LLC	13.88%	9.94M	704.75M	282.87K	+2.93%
Mar 31, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	25.12%	17.99M	1.28B	0	0
Mar 31, 2025	FRANKLIN RESOURCES INC	0.22%	159.63K	11.32M	2	0.00%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0.31%	220.02K	15.6M	-42.75K	-16.27%
Mar 31, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.61%	439.02K	31.14M	39K	+9.75%
Mar 31, 2025	FAIRMOUNT FUNDS MANAGEMENT LLC	1.02%	727.56K	51.6M	-590.1K	-44.78%
Mar 31, 2025		0.63%	450K	31.91M	-670.19K	-59.83%
Mar 31, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	0.63%	450.77K	31.97M	450.77K	+100.00%
Mar 31, 2025	FARALLON CAPITAL MANAGEMENT LLC	0.21%	150K	10.64M	0	0
Mar 31, 2025	SCHONFELD STRATEGIC ADVISORS LLC	0.26%	184.8K	13.11M	184.8K	+100.00%
Mar 31, 2025	SAMLYN CAPITAL, LLC	0.43%	309.59K	21.96M	-443	-0.14%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.44%	317.76K	22.54M	-5.81K	-1.79%
Mar 31, 2025	VESTAL POINT CAPITAL, LP	1.5%	1.08M	76.24M	475K	+79.17%
Mar 31, 2025	CANDRIAM S.C.A.	0.49%	354.13K	25.11M	-13.97K	-3.79%
Mar 31, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.55%	397K	28.16M	-283K	-41.62%
Mar 31, 2025	MARSHALL WACE, LLP	0.59%	421.51K	29.89M	60.47K	+16.75%
Mar 31, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	0.6%	427.53K	30.32M	-2.46K	-0.57%
Mar 31, 2025	LOGOS GLOBAL MANAGEMENT LP	0.7%	500K	35.46M	500K	+100.00%
Mar 31, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	0.74%	531.21K	37.67M	-262.21K	-33.05%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.25%	893.46K	63.38M	21.97K	+2.52%
Mar 31, 2025	WOODLINE PARTNERS LP	1.68%	1.21M	85.5M	604	+0.05%
Mar 31, 2025	JANUS HENDERSON GROUP PLC	1.83%	1.31M	95.73M	1.29M	+7,785.15%
Mar 31, 2025	STATE STREET CORP	2%	1.43M	101.46M	-59.02K	-3.96%
Mar 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	2.01%	1.44M	102.29M	157.81K	+12.28%
Mar 31, 2025	BRAIDWELL LP	1.17%	840.95K	59.64M	599.71K	+248.60%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.05%	27.3K	2.05M	-12.97K	-32.21%
Mar 31, 2024	CREDIT SUISSE AG/	0.05%	28.57K	2.15M	680	+2.44%
Mar 31, 2024	SEI INVESTMENTS CO	0.05%	31.06K	2.34B	1.68K	+5.72%
Mar 31, 2024	BALYASNY ASSET MANAGEMENT L.P.	0.05%	31.08K	2.33M	31.08K	+100.00%
Mar 31, 2024	STATE OF NEW JERSEY COMMON PENSION FUND D	0.06%	32.19K	2.42M	32.19K	+100.00%
Mar 31, 2024	JPMORGAN CHASE & CO	0.06%	34.89K	2.62M	-14.46K	-29.30%
Mar 31, 2024	EAM INVESTORS, LLC	0.06%	34.98K	2.63M	-15.2K	-30.29%
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	0.06%	37.17K	2.79M	-28.92K	-43.76%
Mar 31, 2024	HAP TRADING, LLC	0.06%	37.5K	113.44K	37.5K	+100.00%
Mar 31, 2024	RHUMBLINE ADVISERS	0.07%	39.19K	2.94M	1.88K	+5.03%
Mar 31, 2024	EAM GLOBAL INVESTORS LLC	0.08%	45.29K	3.4M	-17.36K	-27.71%
Mar 31, 2024	SWISS NATIONAL BANK	0.09%	50.9K	3.82M	400	+0.79%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.11%	64.21K	4.82M	127	+0.20%
Mar 31, 2024	UBS GROUP AG	0.14%	84.02K	6.31M	3.39K	+4.20%
Mar 31, 2024	RHENMAN & PARTNERS ASSET MANAGEMENT AB	0.15%	87.5K	6.57M	-25.43K	-22.52%
Mar 31, 2024	FRANKLIN RESOURCES INC	0.33%	194.04K	14.57M	18.6K	+10.60%
Mar 31, 2024	BANK OF MONTREAL /CAN/	0.33%	194.18K	14.6M	105.1K	+117.99%
Mar 31, 2024	WELLINGTON MANAGEMENT GROUP LLP	1.02%	593.6K	44.57M	-419.8K	-41.42%
Mar 31, 2024	DRIEHAUS CAPITAL MANAGEMENT LLC	1.16%	672.88K	50.53M	-264.85K	-28.24%
Mar 31, 2024	CITIGROUP INC	0.18%	102.43K	7.69M	33.58K	+48.76%
Mar 31, 2024	D. E. SHAW & CO., INC.	0.77%	445.38K	33.44M	-22.8K	-4.87%
Mar 31, 2024	BLACKROCK INC.	4.65%	2.71M	203.38M	-12.74K	-0.47%
Mar 31, 2024	PERCEPTIVE ADVISORS LLC	4.78%	2.78M	209.01M	-134.54K	-4.61%
Mar 31, 2024	VANGUARD GROUP INC	5.86%	3.41M	256.21M	72.22K	+2.16%
Mar 31, 2024	PARADIGM BIOCAPITAL ADVISORS LP	7.18%	4.18M	313.71M	319.82K	+8.29%
Mar 31, 2024	FMR LLC	15.11%	8.79M	660.41M	69.79K	+0.80%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.16%	90.26K	6.78M	-335	-0.37%
Mar 31, 2024	UBS ASSET MANAGEMENT AMERICAS INC	0.17%	98.12K	7.37M	73.3K	+295.29%
Mar 31, 2024	IKARIAN CAPITAL, LLC	0.17%	101.6K	7.63M	-156.54K	-60.64%
Mar 31, 2024	RAFFERTY ASSET MANAGEMENT, LLC	0.19%	108.67K	8.16M	-18.38K	-14.47%
Mar 31, 2024	CITADEL ADVISORS LLC	0.19%	109.88K	8.25M	-99.26K	-47.46%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.19%	111.92K	8.4M	-7.5K	-6.28%
Mar 31, 2024	NICHOLAS INVESTMENT PARTNERS, LP	0.21%	122.79K	9.22M	43.59K	+55.04%
Mar 31, 2024	ROCK SPRINGS CAPITAL MANAGEMENT LP	0.22%	125.3K	9.41M	125.3K	+100.00%
Mar 31, 2024	SOLEUS CAPITAL MANAGEMENT, L.P.	0.22%	129.29K	9.71M	-193.6K	-59.96%
Mar 31, 2024	CAPTION MANAGEMENT, LLC	0.23%	132K	9.91M	27K	+25.71%
Mar 31, 2024	ARROWMARK COLORADO HOLDINGS LLC	0.24%	140.96K	10.58M	-58.09K	-29.18%
Mar 31, 2024	AFFINITY ASSET ADVISORS, LLC	0.26%	150K	11.26M	-25K	-14.29%
Mar 31, 2024	SILVERARC CAPITAL MANAGEMENT, LLC	0.27%	157.75K	11.85M	-35.25K	-18.26%
Mar 31, 2024	VICTORY CAPITAL MANAGEMENT INC	0.3%	176.25K	13.23M	-8.88K	-4.79%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.31%	178.37K	13.39M	-40.26K	-18.41%
Mar 31, 2024	EAGLE ASSET MANAGEMENT INC	0.32%	183.65K	14.16M	183.65K	+100.00%
Mar 31, 2024	MORGAN STANLEY	0.32%	184.67K	13.87M	-88.45K	-32.39%
Mar 31, 2024	DIMENSIONAL FUND ADVISORS LP	0.33%	192.81K	14.48M	-91.01K	-32.07%
Mar 31, 2024	PICTET ASSET MANAGEMENT HOLDING SA	0.35%	202.36K	15.19M	8.35K	+4.31%
Mar 31, 2024	RUBRIC CAPITAL MANAGEMENT LP	0.45%	261.87K	19.66M	261.87K	+100.00%
Mar 31, 2024	FIRST TURN MANAGEMENT, LLC	0.46%	265.9K	19.97M	10K	+3.91%
Mar 31, 2024	NORTHERN TRUST CORP	0.46%	267.17K	20.06M	-13.41K	-4.78%
Mar 31, 2024	DEEP TRACK CAPITAL, LP	0.47%	274.51K	20.61M	-175.49K	-39.00%
Mar 31, 2024	CANDRIAM S.C.A.	0.49%	284.01K	21.33M	4K	+1.43%
Mar 31, 2024	LORD, ABBETT & CO. LLC	0.78%	452.19K	33.96M	-1.96K	-0.43%
Mar 31, 2024	FRED ALGER MANAGEMENT, LLC	0.94%	544.37K	40.88M	222.42K	+69.08%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.96%	557.8K	41.89M	283.8K	+103.58%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	1.17%	681.6K	51.19M	26.85K	+4.10%
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	1.47%	858.16K	64.44M	-248.22K	-22.44%
Mar 31, 2024	BOXER CAPITAL, LLC	1.92%	1.12M	84.12M	0	0
Mar 31, 2024	DARWIN GLOBAL MANAGEMENT, LTD.	2.47%	1.44M	107.9M	1.38M	+2,390.49%
Mar 31, 2024	FAIRMOUNT FUNDS MANAGEMENT LLC	3.31%	1.92M	144.52M	0	0
Mar 31, 2024	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	4.63%	2.7M	202.54M	-880K	-24.60%
Mar 31, 2024	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	34.34%	19.99M	1.5B	0	0
Mar 31, 2024	INVESCO LTD.	0.34%	195.14K	14.65M	24.54K	+14.39%
Mar 31, 2024	VOYA INVESTMENT MANAGEMENT LLC	0.39%	228.12K	17.13M	141.41K	+163.09%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.42%	242.04K	18.18M	5.16K	+2.18%
Mar 31, 2024	COMMODORE CAPITAL LP	2.56%	1.49M	111.72M	156.72K	+11.77%
Mar 31, 2024	STATE STREET CORP	2.6%	1.51M	113.69M	-187.13K	-11.00%
Mar 31, 2024	FIRST TRUST ADVISORS LP	0.03%	16.65K	1.25M	-538	-3.13%
Mar 31, 2024	DEKABANK DEUTSCHE GIROZENTRALE	0.03%	17K	1.3M	0	0
Mar 31, 2024	PROFUND ADVISORS LLC	0.03%	17.04K	1.28B	-3.66K	-17.67%
Mar 31, 2024	RENAISSANCE CAPITAL LLC	0.03%	17.33K	1.3M	17.33K	+100.00%
Mar 31, 2024	HARBOR CAPITAL ADVISORS, INC.	0.03%	18.98K	1.43M	18.98K	+100.00%
Mar 31, 2024	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.03%	19.22K	1.44M	19.22K	+100.00%
Mar 31, 2024	READYSTATE ASSET MANAGEMENT LP	0.04%	23K	1.73M	23K	+100.00%
Mar 31, 2024	STATE OF WISCONSIN INVESTMENT BOARD	0.04%	24.35K	1.83M	-1.71K	-6.57%
Mar 31, 2024	NEW YORK STATE COMMON RETIREMENT FUND	0.05%	26.83K	2.01M	4.67K	+21.08%
Mar 31, 2024	LEGAL & GENERAL GROUP PLC	0.05%	27.19K	2.04B	-997	-3.54%
Dec 31, 2023	DIMENSIONAL FUND ADVISORS LP	0.5%	283.82K	20.89M	18.26K	+6.88%
Dec 31, 2023	SOLEUS CAPITAL MANAGEMENT, L.P.	0.57%	322.89K	23.76M	168.47K	+109.10%
Dec 31, 2023	DEEP TRACK CAPITAL, LP	0.79%	450K	33.12M	450K	+100.00%
Dec 31, 2023	LORD, ABBETT & CO. LLC	0.8%	454.15K	33.42M	454.15K	+100.00%
Dec 31, 2023	D. E. SHAW & CO., INC.	0.82%	468.18K	34.45M	150.91K	+47.56%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.15%	654.75K	48.19M	109.4K	+20.06%
Dec 31, 2023	DRIEHAUS CAPITAL MANAGEMENT LLC	1.64%	937.73K	69.01M	-301.68K	-24.34%
Dec 31, 2023	WELLINGTON MANAGEMENT GROUP LLP	1.78%	1.01M	74.58M	1.01M	+100.00%
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	1.94%	1.11M	81.42M	299.45K	+37.11%
Dec 31, 2023	BOXER CAPITAL, LLC	1.96%	1.12M	82.43M	-90K	-7.44%
Dec 31, 2023	COMMODORE CAPITAL LP	2.33%	1.33M	97.95M	502.26K	+60.60%
Dec 31, 2023	STATE STREET CORP	2.98%	1.7M	125.19M	440.77K	+34.97%
Dec 31, 2023	FAIRMOUNT FUNDS MANAGEMENT LLC	3.37%	1.92M	141.63M	-527.19K	-21.50%
Dec 31, 2023	BLACKROCK INC.	4.77%	2.72M	200.25M	291.22K	+11.98%
Dec 31, 2023	PERCEPTIVE ADVISORS LLC	5.11%	2.92M	214.73M	454.54K	+18.45%
Dec 31, 2023	VANGUARD GROUP INC	5.85%	3.34M	245.78M	1.21M	+56.49%
Dec 31, 2023	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	6.27%	3.58M	263.25M	0	0
Dec 31, 2023	PARADIGM BIOCAPITAL ADVISORS LP	6.76%	3.86M	283.91M	2.22M	+135.51%
Dec 31, 2023	FMR LLC	15.28%	8.73M	642.08M	1.11M	+14.51%
Dec 31, 2023	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	35.02%	19.99M	1.47B	0	0
Dec 31, 2023	NICHOLAS INVESTMENT PARTNERS, LP	0.14%	79.2K	5.83M	-189.14K	-70.49%
Dec 31, 2023	UBS GROUP AG	0.14%	80.63K	5.93M	61.76K	+327.34%
Dec 31, 2023	JANE STREET GROUP, LLC	0.15%	84.72K	6.23M	29.85K	+54.41%
Dec 31, 2023	VOYA INVESTMENT MANAGEMENT LLC	0.15%	86.71K	6.38M	77.08K	+800.38%
Dec 31, 2023	BARCLAYS PLC	0.15%	88.11K	6.48M	36.86K	+71.94%
Dec 31, 2023	BANK OF MONTREAL /CAN/	0.16%	89.08K	6.69M	89.08K	+100.00%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.16%	90.6K	6.67M	25.88K	+39.98%
Dec 31, 2023	CAPTION MANAGEMENT, LLC	0.18%	105K	7.73M	105K	+100.00%
Dec 31, 2023	RHENMAN & PARTNERS ASSET MANAGEMENT AB	0.2%	112.93K	8.31M	26.92K	+31.30%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.21%	119.41K	8.79M	36.11K	+43.34%
Dec 31, 2023	RAFFERTY ASSET MANAGEMENT, LLC	0.22%	127.05K	9.35M	31.33K	+32.73%
Dec 31, 2023	INVESCO LTD.	0.3%	170.6K	12.55M	-38.09K	-18.25%
Dec 31, 2023	AFFINITY ASSET ADVISORS, LLC	0.31%	175K	12.88M	125K	+250.00%
Dec 31, 2023	FRANKLIN RESOURCES INC	0.31%	175.44K	12.91M	21.39K	+13.89%
Dec 31, 2023	AVORO CAPITAL ADVISORS LLC	0.31%	178.92K	13.17M	-633.58K	-77.98%
Dec 31, 2023	VICTORY CAPITAL MANAGEMENT INC	0.32%	185.12K	13.62M	-23.85K	-11.41%
Dec 31, 2023	SILVERARC CAPITAL MANAGEMENT, LLC	0.34%	193K	14.2M	193K	+100.00%
Dec 31, 2023	ARROWMARK COLORADO HOLDINGS LLC	0.35%	199.05K	14.65M	-70.71K	-26.21%
Dec 31, 2023	CITADEL ADVISORS LLC	0.37%	209.14K	15.39M	208.93K	+100,934.30%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.38%	218.63K	16.09M	138.52K	+172.93%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.41%	236.88K	17.43M	38.9K	+19.65%
Dec 31, 2023		0.34%	194K	14.28M	194K	+100.00%
Dec 31, 2023	IKARIAN CAPITAL, LLC	0.18%	104.4K	7.68M	102.01K	+4,259.08%
Dec 31, 2023	MORGAN STANLEY	0.48%	273.12K	20.1M	100.89K	+58.58%
Dec 31, 2023	CANDRIAM S.C.A.	0.49%	280.01K	20.61M	-70.01K	-20.00%
Dec 31, 2023	NORTHERN TRUST CORP	0.49%	280.57K	20.65M	33.47K	+13.54%
Dec 31, 2023	FRED ALGER MANAGEMENT, LLC	0.56%	321.95K	23.69M	241.92K	+302.25%

Insiders

Insiders	Designation	Shares Held
FLYNN JAMES E	Director by Deputization	8.3M
HACK ANDREW A. F.	director	1.45M
PORTER JAMES RICHARD	President and CEO	278.63K
SHAIR MATTHEW	director	201.67K
BALCOM ALEXANDRA	Chief Financial Officer	81.73K
PELISH HENRY E.	Chief Scientific Officer	65.89K
MILLER DEBORAH ANN	Chief Legal Officer	59.63K
NOCI DARLENE	Chief Development Officer	58.12K
TURNER CHRISTOPHER DURANT	Chief Medical Officer	55.13K
CONLEY EMILY	director	2.51K
PROTOPAPAS ANNA	director	0

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Jan 29, 2026	NOCI DARLENE	SALE	103.39	63	6.51K	58.12K
Jan 22, 2026	MILLER DEBORAH ANN	SALE	110.16	14.3K	1.58M	59.63K
Jan 21, 2026	MILLER DEBORAH ANN	SALE	109.84	700	76.89K	59.63K
Jan 06, 2026	NOCI DARLENE	SALE	98.40	225	22.14K	40.62K
Jan 06, 2026	PORTER JAMES RICHARD	SALE	98.40	675	66.42K	278.63K
Jan 06, 2026	BALCOM ALEXANDRA	SALE	98.40	225	22.14K	81.73K
Jan 06, 2026	TURNER CHRISTOPHER DURANT	SALE	98.40	225	22.14K	55.13K
Jan 06, 2026	MILLER DEBORAH ANN	SALE	98.40	183	18.01K	42.13K
Jan 06, 2026	PELISH HENRY E.	SALE	98.40	189	18.6K	65.89K
Jan 05, 2026	MILLER DEBORAH ANN	SALE	98.52	326	32.12K	44.72K
Jan 05, 2026	NOCI DARLENE	SALE	98.52	317	31.23K	43.8K
Jan 05, 2026	PELISH HENRY E.	SALE	98.52	186	18.32K	68.55K
Jan 05, 2026	PORTER JAMES RICHARD	SALE	98.52	1.34K	131.72K	288.17K
Jan 05, 2026	TURNER CHRISTOPHER DURANT	SALE	98.52	317	31.23K	58.31K
Jan 05, 2026	BALCOM ALEXANDRA	SALE	98.52	317	31.23K	84.91K
Jan 02, 2026	MILLER DEBORAH ANN	SALE	101.47	540	54.79K	49.09K
Dec 30, 2025	NOCI DARLENE	SALE	101.22	642	64.98K	48.03K
Dec 08, 2025	BALCOM ALEXANDRA	SALE	111.32	100	11.13K	54.65K
Nov 28, 2025	NOCI DARLENE	SALE	108.72	3.36K	364.76K	48.03K
Nov 24, 2025	FLYNN JAMES E	SALE	95.44	371.29K	35.44M	8.3M
Nov 24, 2025	SHAIR MATTHEW	SALE	110.42	336	37.1K	201.67K
Nov 18, 2025	BALCOM ALEXANDRA	SALE	104.54	509	53.21K	61.73K
Nov 17, 2025	BALCOM ALEXANDRA	SALE	103.68	380	39.4K	61.73K
Nov 17, 2025	MILLER DEBORAH ANN	SALE	107.04	608	65.08K	49.09K
Oct 30, 2025	MILLER DEBORAH ANN	SALE	104.78	9.38K	983.05K	49.09K
Oct 30, 2025	NOCI DARLENE	SALE	104.58	218	22.8K	48.03K
Oct 28, 2025	SHAIR MATTHEW	SALE	100.27	9.15K	917.87K	203.32K
Oct 27, 2025	SHAIR MATTHEW	SALE	100.23	4.05K	405.53K	212.48K
Oct 20, 2025	MILLER DEBORAH ANN	SALE	94.91	5K	474.55K	49.09K
Oct 16, 2025	PORTER JAMES RICHARD	SALE	92.63	700	64.84K	249.06K
Oct 16, 2025	MILLER DEBORAH ANN	SALE	92.50	4.9K	453.25K	49.09K
Oct 15, 2025	BALCOM ALEXANDRA	SALE	85.57	1.68K	144.01K	61.73K
Oct 15, 2025	MILLER DEBORAH ANN	SALE	89.98	15.62K	1.41M	49.09K
Oct 15, 2025	PELISH HENRY E.	SALE	90.04	14.21K	1.28M	65.96K
Oct 14, 2025	PELISH HENRY E.	SALE	87.39	400	34.96K	65.96K
Oct 14, 2025	BALCOM ALEXANDRA	SALE	88.90	200	17.78K	61.73K
Oct 13, 2025	PELISH HENRY E.	SALE	89.81	7.64K	685.88K	65.96K
Oct 13, 2025	BALCOM ALEXANDRA	SALE	89.22	1.6K	142.4K	61.73K
Oct 01, 2025	BALCOM ALEXANDRA	SALE	86.37	970	83.78K	61.73K
Sep 30, 2025	BALCOM ALEXANDRA	SALE	85.06	20K	1.7M	61.73K
Sep 29, 2025	NOCI DARLENE	SALE	84.92	417	35.41K	48.03K
Sep 29, 2025	BALCOM ALEXANDRA	SALE	85.01	7.59K	645.06K	61.73K
Sep 15, 2025	PORTER JAMES RICHARD	SALE	80.12	2.1K	168.01K	249.06K
Sep 10, 2025	PELISH HENRY E.	SALE	78.83	3.73K	293.64K	65.96K
Aug 25, 2025	NOCI DARLENE	SALE	75.63	109	8.24K	48.03K
Aug 15, 2025	PORTER JAMES RICHARD	SALE	76.90	100	7.69K	249.06K
Aug 07, 2025	PELISH HENRY E.	SALE	74.85	5.5K	411.68K	60.96K
Jul 30, 2025	NOCI DARLENE	SALE	80.36	4K	321.44K	48.03K
Jul 16, 2025	BALCOM ALEXANDRA	SALE	85.10	14.7K	1.25M	61.73K
Jul 15, 2025	PORTER JAMES RICHARD	SALE	84.53	104	8.79K	249.06K
Jul 15, 2025	BALCOM ALEXANDRA	SALE	85.48	54	4.62K	61.73K
Jul 10, 2025	PELISH HENRY E.	SALE	80.92	240	19.42K	60.96K
Jul 09, 2025	PELISH HENRY E.	SALE	81.90	200	16.38K	60.96K
Jun 27, 2025	PELISH HENRY E.	SALE	79.92	2.17K	173.43K	63.1K
Jun 27, 2025	BALCOM ALEXANDRA	SALE	80.02	20K	1.6M	61.73K
Jun 26, 2025	NOCI DARLENE	SALE	79.15	306	24.22K	48.03K
Jun 25, 2025	PELISH HENRY E.	SALE	79.87	8.63K	689.28K	63.1K
Jun 16, 2025	PORTER JAMES RICHARD	SALE	78.22	200	15.64K	249.06K
Jun 06, 2025	PELISH HENRY E.	SALE	79.82	200	15.96K	63.1K
May 29, 2025	NOCI DARLENE	SALE	71.67	563	40.35K	48.03K
May 15, 2025	PORTER JAMES RICHARD	SALE	70.77	335	23.71K	249.06K
Apr 29, 2025	NOCI DARLENE	SALE	74.56	4K	298.24K	48.03K
Apr 15, 2025	PORTER JAMES RICHARD	SALE	70.73	488	34.52K	249.06K
Mar 27, 2025	NOCI DARLENE	SALE	73.83	900	66.45K	48.03K
Mar 17, 2025	PORTER JAMES RICHARD	SALE	76.69	601	46.09K	249.06K
Mar 07, 2025	NOCI DARLENE	SALE	72.59	1.1K	79.85K	48.03K
Mar 06, 2025	NOCI DARLENE	SALE	72.60	4.31K	312.62K	48.03K
Feb 24, 2025	SHAIR MATTHEW	SALE	79.13	302	23.9K	216.52K
Feb 18, 2025	PORTER JAMES RICHARD	SALE	79.01	800	63.21K	249.06K
Jan 27, 2025	SHAIR MATTHEW	SALE	85.00	108	9.18K	218.52K
Jan 15, 2025	PORTER JAMES RICHARD	SALE	77.28	5.84K	451.47K	249.06K
Jan 06, 2025	NOCI DARLENE	SALE	80.54	2.17K	175.01K	48.03K
Jan 06, 2025	PORTER JAMES RICHARD	SALE	80.54	9.36K	753.85K	249.06K
Jan 06, 2025	MILLER DEBORAH ANN	SALE	80.54	1.6K	129.19K	49.09K
Jan 06, 2025	BALCOM ALEXANDRA	SALE	80.54	2.17K	175.01K	61.73K
Jan 06, 2025	PELISH HENRY E.	SALE	80.54	1.34K	108.17K	59.98K
Jan 06, 2025	TURNER CHRISTOPHER DURANT	SALE	80.54	2.17K	175.01K	62.55K
Dec 23, 2024	SHAIR MATTHEW	SALE	84.17	591	49.74K	220.52K
Dec 16, 2024	PORTER JAMES RICHARD	SALE	86.96	8.03K	698.38K	188.11K
Dec 11, 2024	HACK ANDREW A. F.	SALE	88.00	1.25M	110M	1.45M
Nov 29, 2024	BALCOM ALEXANDRA	SALE	96.25	1.86K	178.83K	33.3K
Nov 25, 2024	SHAIR MATTHEW	SALE	97.40	30	2.92K	222.52K
Nov 15, 2024	PORTER JAMES RICHARD	SALE	89.98	1.11K	99.97K	188.11K
Nov 01, 2024	NOCI DARLENE	SALE	90.03	500	45.02K	33.3K
Oct 31, 2024	BALCOM ALEXANDRA	SALE	90.94	100	9.09K	33.3K
Oct 28, 2024	SHAIR MATTHEW	SALE	93.11	73	6.8K	224.52K
Oct 22, 2024	FLYNN JAMES E	SALE	97.75	1M	97.75M	8.67M
Oct 15, 2024	PORTER JAMES RICHARD	SALE	103.01	814	83.85K	188.11K
Oct 01, 2024	NOCI DARLENE	SALE	104.69	174	18.22K	33.3K
Sep 30, 2024	BALCOM ALEXANDRA	SALE	101.89	2.96K	301.9K	33.3K
Sep 23, 2024	SHAIR MATTHEW	SALE	107.82	23	2.48K	226.52K
Sep 16, 2024	PELISH HENRY E.	SALE	94.80	3.75K	355.88K	60.38K
Sep 16, 2024	MILLER DEBORAH ANN	SALE	102.00	300	30.6K	33.3K
Sep 09, 2024	MILLER DEBORAH ANN	SALE	89.11	161	14.35K	33.3K
Sep 03, 2024	NOCI DARLENE	SALE	85.64	512	43.85K	33.3K
Aug 30, 2024	BALCOM ALEXANDRA	SALE	85.96	288	24.76K	33.3K
Aug 26, 2024	SHAIR MATTHEW	SALE	85.53	156	13.34K	228.52K
Aug 23, 2024	PELISH HENRY E.	SALE	85.08	10.5K	893.34K	66.1K
Aug 23, 2024	CONLEY EMILY	SALE	85.02	3.33K	283.46K	2.51K
Aug 23, 2024	MILLER DEBORAH ANN	SALE	85.04	11K	935.44K	33.3K
Aug 08, 2024	MILLER DEBORAH ANN	SALE	69.95	374	26.16K	33.3K
Aug 01, 2024	NOCI DARLENE	SALE	80.32	63	5.06K	33.3K
Jul 31, 2024	BALCOM ALEXANDRA	SALE	81.31	1.14K	92.29K	33.3K
Jul 29, 2024	SHAIR MATTHEW	SALE	81.71	91	7.44K	230.52K
Jul 15, 2024	CONLEY EMILY	SALE	81.93	205	16.8K	2.51K
Jul 12, 2024	MILLER DEBORAH ANN	SALE	80.16	6K	480.96K	33.3K
Jul 08, 2024	MILLER DEBORAH ANN	SALE	73.84	699	51.61K	33.3K
Jul 01, 2024	NOCI DARLENE	SALE	76.19	542	41.29K	33.3K
Jun 28, 2024	BALCOM ALEXANDRA	SALE	76.73	572	43.89K	33.3K
Jun 24, 2024	SHAIR MATTHEW	SALE	80.98	190	15.39K	232.52K
Jun 14, 2024	CONLEY EMILY	SALE	78.31	223	17.46K	2.51K
Jun 06, 2024	MILLER DEBORAH ANN	SALE	82.33	1.57K	128.93K	33.3K
May 28, 2024	SHAIR MATTHEW	SALE	68.64	16	1.1K	234.52K
May 15, 2024	CONLEY EMILY	SALE	69.09	5K	345.45K	8
May 13, 2024	SHAIR MATTHEW	SALE	66.86	4.46K	298.33K	1.42M
May 06, 2024	SHAIR MATTHEW	SALE	70.27	7.9K	555.13K	1.46M
May 02, 2024	MILLER DEBORAH ANN	SALE	73.13	138	10.09K	33.3K
Apr 29, 2024	SHAIR MATTHEW	SALE	68.57	85	5.83K	236.52K
Apr 22, 2024	SHAIR MATTHEW	SALE	64.52	14.65K	945.22K	1.54M
Apr 15, 2024	SHAIR MATTHEW	SALE	66.17	11.9K	787.42K	1.57M
Apr 15, 2024	CONLEY EMILY	SALE	66.66	6	399.96	8
Apr 08, 2024	SHAIR MATTHEW	SALE	69.64	1K	69.64K	1.61M
Apr 04, 2024	MILLER DEBORAH ANN	SALE	74.81	1.49K	111.54K	33.3K
Apr 01, 2024	SHAIR MATTHEW	SALE	77.19	9.69K	748.28K	1.65M
Mar 28, 2024	MILLER DEBORAH ANN	SALE	75.94	3.04K	231.16K	33.3K
Mar 27, 2024	HACK ANDREW A. F.	SALE	72.31	791.8K	57.25M	2.7M
Mar 25, 2024	SHAIR MATTHEW	SALE	77.37	105	8.12K	238.52K
Mar 22, 2024	NOCI DARLENE	SALE	78.72	600	47.23K	33.3K
Mar 15, 2024	CONLEY EMILY	SALE	84.44	1K	84.44K	8
Dec 28, 2023	SHAIR MATTHEW	SALE	76.14	13.49K	1.03M	1.72M
Dec 27, 2023	SHAIR MATTHEW	SALE	75.17	1K	75.17K	1.77M
Dec 26, 2023	SHAIR MATTHEW	SALE	75.13	68.67K	5.16M	1.77M
Dec 19, 2023	MILLER DEBORAH ANN	SALE	75.00	5K	375K	0
Dec 18, 2023	BALCOM ALEXANDRA	SALE	75.82	30K	2.27M	0
Dec 18, 2023	PROTOPAPAS ANNA	SALE	75.67	5K	378.35K	0
Dec 18, 2023	MILLER DEBORAH ANN	SALE	75.82	33.05K	2.51M	0
Dec 18, 2023	NOCI DARLENE	SALE	75.82	40K	3.03M	0
Nov 28, 2023	SHAIR MATTHEW	SALE	62.37	2.8K	174.51K	1.84M
Nov 01, 2023	NOCI DARLENE	SALE	53.11	976	51.84K	0
Oct 24, 2023	SHAIR MATTHEW	SALE	51.23	10.17K	520.96K	1.85M
Oct 04, 2023	TURNER CHRISTOPHER DURANT	SALE	57.18	500	28.59K	15.98K
Oct 04, 2023	NOCI DARLENE	SALE	57.54	5.4K	310.72K	0
Oct 02, 2023	NOCI DARLENE	SALE	46.01	2.14K	98.65K	111
Sep 15, 2023	MILLER DEBORAH ANN	SALE	47.99	756	36.28K	0
Sep 01, 2023	NOCI DARLENE	SALE	46.86	1.8K	84.35K	0
Aug 15, 2023	MILLER DEBORAH ANN	SALE	43.01	709	30.49K	0
Aug 01, 2023	NOCI DARLENE	SALE	49.69	964	47.9K	2.04K
Jul 31, 2023	BALCOM ALEXANDRA	SALE	49.49	10.85K	536.87K	0
Jul 28, 2023	MILLER DEBORAH ANN	SALE	48.52	6.5K	315.38K	0
Jul 28, 2023	TURNER CHRISTOPHER DURANT	SALE	48.93	2.67K	130.4K	14.51K
Jul 26, 2023	TURNER CHRISTOPHER DURANT	SALE	46.85	2.37K	110.8K	14.51K
Jul 24, 2023	TURNER CHRISTOPHER DURANT	SALE	46.82	200	9.36K	14.51K
Jul 20, 2023	NOCI DARLENE	SALE	45.17	10.94K	494.2K	0
Jul 20, 2023	TURNER CHRISTOPHER DURANT	SALE	46.80	100	4.68K	14.51K
Jul 19, 2023	NOCI DARLENE	SALE	45.04	4.56K	205.34K	0
Jul 17, 2023	MILLER DEBORAH ANN	SALE	43.93	298	13.09K	0
Jul 03, 2023	NOCI DARLENE	SALE	42.12	553	23.29K	0
Jun 16, 2023	NOCI DARLENE	SALE	45.19	2.9K	131.05K	0
Jun 15, 2023	MILLER DEBORAH ANN	SALE	44.86	164	7.36K	0
Jun 15, 2023	NOCI DARLENE	SALE	45.07	1K	45.07K	0
Jun 05, 2023	TURNER CHRISTOPHER DURANT	SALE	44.86	10.24K	459.14K	14.51K
Jun 05, 2023	NOCI DARLENE	SALE	45.00	600	27K	0
Jun 01, 2023	NOCI DARLENE	SALE	41.46	239	9.91K	2.76K
May 15, 2023	MILLER DEBORAH ANN	SALE	40.31	502	20.24K	1.5K
May 09, 2023	MILLER DEBORAH ANN	SALE	39.63	1.33K	52.79K	0
May 05, 2023	MILLER DEBORAH ANN	SALE	39.64	2.8K	110.99K	0
May 01, 2023	NOCI DARLENE	SALE	35.71	28	999.88	2.97K
May 01, 2023	MILLER DEBORAH ANN	SALE	39.61	900	35.65K	0
Apr 17, 2023	MILLER DEBORAH ANN	SALE	29.33	125	3.67K	1.88K
Apr 03, 2023	NOCI DARLENE	SALE	26.57	2.89K	76.73K	112
Mar 15, 2023	MILLER DEBORAH ANN	SALE	28.17	1.84K	51.8K	161
Mar 01, 2023	NOCI DARLENE	SALE	29.81	2.6K	77.51K	400
Feb 15, 2023	MILLER DEBORAH ANN	SALE	29.51	1.84K	54.36K	158
Feb 02, 2023	NOCI DARLENE	SALE	29.37	1.99K	58.39K	1.01K
Jan 17, 2023	MILLER DEBORAH ANN	SALE	32.15	709	22.79K	1.29K
Jan 04, 2023	SHAIR MATTHEW	SALE	27.92	16.02K	447.17K	1.95M
Dec 15, 2022	NOCI DARLENE	SALE	29.53	3.4K	100.4K	800
Dec 15, 2022	MILLER DEBORAH ANN	SALE	29.47	1.32K	39.02K	676
Dec 07, 2022	SHAIR MATTHEW	SALE	30.98	12.71K	393.63K	1.97M
Nov 15, 2022	MILLER DEBORAH ANN	SALE	31.24	600	18.74K	1.4K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES506.88K44

NET SHARES-506.88K44

SHARES HELD12.04M44

% NET SHARES-104.21%0%

NUVL Stock Ownership Breakdown

Nuvalent

Stock Outstanding Shares

Market Insider

Institutional Ownership

Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions

Stock Outstanding Shares

Market Insider

Institutional Ownership

Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions