How many institutions own MRUS stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own MRUS shares is 294, representing 103.8% of the company's common stock.

Who are the major shareholders selling Merus N.V. stock?

TD ASSET MANAGEMENT INC, in the last quarter, reduced its stake in MRUS by -29.77% restricting it's holding to 62.58 thousand shares of worth nearly $5.89M. MOODY ALDRICH PARTNERS LLC also lessened -16.92% of the MRUS shares from its portfolio, reducing its holding to 76.44 thousand shares of worth $7.20M. ROCK SPRINGS CAPITAL MANAGEMENT LP also shunned MRUS shares holding by -43.87% last quarter which brought its holding to 597.05 thousand shares worth $56.21M.

Investors who are buying MRUS stock?

As per its latest 13F filing, SUSQUEHANNA INTERNATIONAL GROUP, LLP increased its stake in MRUS by 303.68% in the last quarter. The institutional holder raised its holding to 417.4 thousand shares having worth more than $39.30M. PERCEPTIVE ADVISORS LLC also added 91.07% more shares of MRUS to its portfolio, raising its holding to 1.35 million shares of worth $127.39M. ABSOLUTE GESTAO DE INVESTIMENTOS LTDA. also increased its MRUS shares holding by 100% which brought its holding to 330.59 thousand shares worth $31.12M.

MRUS's major insiders: who are they?

The insider with the most stakes in MRUS is BVF PARTNERS L P/IL , 10 percent owner at the company. Additionally, MRUS stock is highly held by EVP & Chief Scientific Officer Throsby Mark and President, CEO & PFO Lundberg Sven Ante among others.

Did an insider recently sell MRUS stock?

Company executives, directors, and other insiders own 2.29% percent of Merus N.V.'s stock. Within the last six months, there have been 2 transaction(s) in which MRUS insiders have sold stock, totaling 10K shares. Insiders that have sold shares include SHUMAN HARRY, SILVERMAN PETER B., and BVF PARTNERS L P/IL.

Which insider recently purchased MRUS stock?

There have been 9 transaction(s) during the past 6-months in which Merus N.V. insiders have bought stock, totalling 77092999 shares

How much of MRUS does insiders own?

Around 577.44M Merus N.V. shares are held by insiders, which represents about 2.29% of MRUS stock.

Who is the insider with the largest stake?

MRUS 10 percent owner, BVF PARTNERS L P/IL holds the largest portfolio of the company's shares. MRUS shares owned by BVF total nearly 232.75 thousand.

Which institution holds the most shares in MRUS?

SUSQUEHANNA INTERNATIONAL GROUP, LLP is the largest institutional owner in MRUS which holds 417.4 thousand shares worth $39.30M or 0.59% of the total MRUS shares outstanding followed by PERCEPTIVE ADVISORS LLC with ownership of 1.35 million shares representing 1.9% of the MRUS ownership. ABSOLUTE GESTAO DE INVESTIMENTOS LTDA. is the third largest stakeholder with 330.59 thousand shares or 0.47% of the ownership worth more than $31.12M.

Is Merus N.V. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the MRUS is concerned, it is a stock which is optionable.

Is there a short position on MRUS's shares?

Number of MRUS shares short is 4.44M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding MRUS shares are there?

As of today, 75.63M shares of MRUS are outstanding.

Is there many float in MRUS stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, MRUS has 65.61M shares in float.

MRUS short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for MRUS is 6.49.

Merus NV (MRUS) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableNo

OptionableYes

Short Percent Of Outstanding Shares5.87

Short Percent Of Float5.9

Shares Outstanding75.63M

Shares Float65.61M

Shares Short4.44M

Short Ratio6.49

5.9%

Short % of Float

5.87%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

2.29% Percentage of Shares held by All Insiders

103.8% Percentage of Shares held by All Institutions

106.23% Percentage of Float held by Institutions

294

Number of Institutions Holding Shares

Institutional Ownership

About 103.8% of MRUS shares are held by financial institutions. SUSQUEHANNA INTERNATIONAL GROUP, LLP is the top corporate investor, holding 417.4K shares valued at $39.30M. A 0.59% stake in Merus N.V. is owned by the company. PERCEPTIVE ADVISORS LLC owns 1.35M shares valued at $127.39M, which translates its holding of 1.9% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Sep 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.59%	417.4K	39.3M	314K	+303.68%
Sep 30, 2025	PERCEPTIVE ADVISORS LLC	1.9%	1.35M	127.39M	644.92K	+91.07%
Sep 30, 2025	ABSOLUTE GESTAO DE INVESTIMENTOS LTDA.	0.47%	330.59K	31.12M	330.59K	+100.00%
Sep 30, 2025	BANK OF MONTREAL /CAN/	0.08%	60.21K	5.67M	38.07K	+171.95%
Sep 30, 2025	TD ASSET MANAGEMENT INC	0.09%	62.58K	5.89M	-26.53K	-29.77%
Sep 30, 2025	HAP TRADING, LLC	0.09%	65K	21.13M	65K	+100.00%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.1%	68K	6.39M	7.05K	+11.56%
Sep 30, 2025	VESTCOR INC	0.1%	70K	6.59M	70K	+100.00%
Sep 30, 2025	FIRST TRUST ADVISORS LP	0.1%	72.99K	6.87M	72.99K	+100.00%
Sep 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0.11%	76.36K	7.19M	44.09K	+136.65%
Sep 30, 2025	MOODY ALDRICH PARTNERS LLC	0.11%	76.44K	7.2M	-15.57K	-16.92%
Sep 30, 2025	ATHOS CAPITAL LTD	0.11%	80K	7.53M	80K	+100.00%
Sep 30, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	0.84%	597.05K	56.21M	-466.56K	-43.87%
Sep 30, 2025	INVESCO LTD.	0.77%	548.52K	51.64M	-284.84K	-34.18%
Sep 30, 2025	SLOTNIK CAPITAL, LLC	0.13%	90K	8.47M	90K	+100.00%
Sep 30, 2025	CREDIT INDUSTRIEL ET COMMERCIAL	0.13%	90K	8.47M	90K	+100.00%
Sep 30, 2025	CITIGROUP INC	0.13%	95.22K	8.97M	60.72K	+175.96%
Sep 30, 2025	PICTON MAHONEY ASSET MANAGEMENT	0.14%	100K	9.42M	100K	+100.00%
Sep 30, 2025	SWISS NATIONAL BANK	0.14%	101.05K	9.51M	8.7K	+9.42%
Sep 30, 2025	GABELLI & CO INVESTMENT ADVISERS, INC.	0.15%	103.45K	9.74M	103.45K	+100.00%
Sep 30, 2025	DEUTSCHE BANK AG\	0.15%	104.11K	9.8M	-9.4K	-8.28%
Sep 30, 2025	GABELLI FUNDS LLC	0.15%	105.05K	9.89M	105.05K	+100.00%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.17%	121.78K	11.47M	-10.79K	-8.14%
Sep 30, 2025	VICTORY CAPITAL MANAGEMENT INC	0.18%	131.43K	12.37M	19.99K	+17.94%
Sep 30, 2025	BARCLAYS PLC	0.2%	144.04K	13.56M	110.39K	+328.14%
Sep 30, 2025	NAN FUNG TRINITY (HK) LTD	0.21%	150.34K	14.15M	0	0
Sep 30, 2025	ABRDN PLC	0.22%	155.15K	14.61M	29.38K	+23.36%
Sep 30, 2025	TIMESSQUARE CAPITAL MANAGEMENT, LLC	0.23%	166K	15.63M	-76.7K	-31.60%
Sep 30, 2025	CARMIGNAC GESTION	0.24%	167.53K	15.77M	-47.19K	-21.98%
Sep 30, 2025	ALLIANZ ASSET MANAGEMENT GMBH	0.27%	192.1K	18.09M	166.1K	+638.85%
Sep 30, 2025	HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND	0.27%	192.5K	18.12M	192.5K	+100.00%
Sep 30, 2025	TWIN SECURITIES, INC.	0.44%	310.26K	29.21M	310.26K	+100.00%
Sep 30, 2025	OCTAGON CAPITAL ADVISORS LP	0.43%	308K	29M	-81K	-20.82%
Sep 30, 2025	ARTIA GLOBAL PARTNERS LP	0.42%	296.75K	27.94M	0	0
Sep 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.4%	285.77K	26.91M	215.77K	+308.24%
Sep 30, 2025	VERSOR INVESTMENTS LP	0.28%	198.79K	18.72M	198.79K	+100.00%
Sep 30, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.3%	210.3K	19.8M	-23.17K	-9.92%
Sep 30, 2025	READYSTATE ASSET MANAGEMENT LP	0.34%	238.7K	22.47M	160.2K	+204.07%
Sep 30, 2025	VANGUARD GROUP INC	0.4%	282.88K	26.63M	17.52K	+6.60%
Sep 30, 2025	FIRST TURN MANAGEMENT, LLC	0.52%	372.02K	35.03M	79.06K	+26.99%
Sep 30, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.59%	422.28K	39.76M	418K	+9,777.82%
Sep 30, 2025	GILEAD SCIENCES, INC.	0.64%	452.53K	42.61M	0	0
Sep 30, 2025	VERITION FUND MANAGEMENT LLC	0.7%	498.9K	46.97M	494.92K	+12,444.63%
Sep 30, 2025	BAKER BROS. ADVISORS LP	0.81%	574.38K	54.08M	0	0
Sep 30, 2025	HUDSON BAY CAPITAL MANAGEMENT LP	1.04%	740.39K	69.71M	725.84K	+4,988.27%
Sep 30, 2025	NOVO HOLDINGS A/S	1.05%	750K	70.61M	0	0
Sep 30, 2025	JPMORGAN CHASE & CO	1.06%	756.01K	71.18M	65.07K	+9.42%
Sep 30, 2025	ALPINE ASSOCIATES MANAGEMENT INC.	1.18%	835.6K	78.67M	835.6K	+100.00%
Sep 30, 2025	AMERIPRISE FINANCIAL INC	1.26%	898.82K	84.62M	-235.04K	-20.73%
Sep 30, 2025	PENTWATER CAPITAL MANAGEMENT LP	1.36%	970K	91.33M	970K	+100.00%
Sep 30, 2025	MAGNETAR FINANCIAL LLC	1.47%	1.05M	98.41M	1.05M	+100.00%
Sep 30, 2025	KRYGER CAPITAL LTD	1.48%	1.05M	99.19M	1.05M	+100.00%
Sep 30, 2025	AVORO CAPITAL ADVISORS LLC	4.98%	3.54M	333.53M	386.95K	+12.26%
Sep 30, 2025	PARADIGM BIOCAPITAL ADVISORS LP	6.15%	4.37M	411.79M	91.82K	+2.14%
Sep 30, 2025	UBS GROUP AG	0.82%	581.07K	54.71M	3.38K	+0.58%
Sep 30, 2025	TUDOR INVESTMENT CORP ET AL	1.03%	731.15K	68.84M	731.15K	+100.00%
Sep 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.65%	459.09K	43.22M	-3.27M	-87.68%
Sep 30, 2025	JANUS HENDERSON GROUP PLC	0.93%	662.14K	62.33M	-167.42K	-20.18%
Sep 30, 2025	TIG ADVISORS, LLC	1.22%	868.15K	81.74M	868.15K	+100.00%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	1.68%	1.2M	112.55M	1.09M	+1,021.21%
Sep 30, 2025	ALLIANCEBERNSTEIN L.P.	1.68%	1.2M	112.63M	93.97K	+8.52%
Sep 30, 2025	FEDERATED HERMES, INC.	1.76%	1.25M	117.61M	-279.43K	-18.28%
Sep 30, 2025	LMR PARTNERS LLP	0.55%	390.47K	36.76M	390.47K	+100.00%
Sep 30, 2025	SOROS FUND MANAGEMENT LLC	0.57%	405K	38.13M	405K	+100.00%
Sep 30, 2025	TANG CAPITAL MANAGEMENT LLC	0.84%	600K	56.49M	0	0
Sep 30, 2025	FIL LTD	0.48%	338K	31.82M	338K	+100.00%
Sep 30, 2025	LYNX1 CAPITAL MANAGEMENT LP	2.16%	1.53M	144.44M	-34.7K	-2.21%
Sep 30, 2025	GLAZER CAPITAL, LLC	2.28%	1.62M	152.46M	1.62M	+100.00%
Sep 30, 2025	WOODLINE PARTNERS LP	2.35%	1.67M	157.62M	131.27K	+8.51%
Sep 30, 2025	RTW INVESTMENTS, LP	2.85%	2.03M	190.68M	-1.98M	-49.38%
Sep 30, 2025	WESTFIELD CAPITAL MANAGEMENT CO LP	3%	2.13M	200.77M	90.1K	+4.41%
Sep 30, 2025	BLACKROCK, INC.	3.06%	2.17M	204.5M	1.12M	+106.67%
Sep 30, 2025	FMR LLC	3.95%	2.81M	264.65M	-4.68M	-62.47%
Sep 30, 2025	HBK INVESTMENTS L P	4.01%	2.85M	268.33M	2.85M	+100.00%
Sep 30, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	4.29%	3.05M	286.87M	-337.71K	-9.98%
Sep 30, 2025	MILLENNIUM MANAGEMENT LLC	0.98%	699.03K	65.81M	683.23K	+4,325.35%
Sep 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.46%	330.23K	31.09M	-585.02K	-63.92%
Sep 30, 2025	MAN GROUP PLC	0.51%	361.7K	34.05M	361.7K	+100.00%
Sep 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.84%	600K	56.49M	-233.4K	-28.01%
Sep 30, 2025	CITADEL ADVISORS LLC	0.86%	614.54K	57.86M	278.94K	+83.12%
Sep 30, 2025	BALYASNY ASSET MANAGEMENT L.P.	0.91%	644.28K	60.66M	644.28K	+100.00%
Sep 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.53%	1.09M	102.36M	-1.17M	-51.94%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.44%	311.57K	29.33M	161.6K	+107.76%
Sep 30, 2025	DEKABANK DEUTSCHE GIROZENTRALE	0.08%	56K	5.13M	0	0
Sep 30, 2025	HIGHBRIDGE CAPITAL MANAGEMENT LLC	0.08%	58.61K	5.52M	58.61K	+100.00%
Sep 30, 2025	GROUPE LA FRANCAISE	0.08%	60K	5.65M	60K	+100.00%
Sep 30, 2025	COMMODORE CAPITAL LP	4.96%	3.53M	331.88M	0	0
Sep 30, 2025	FRANKLIN RESOURCES INC	0.71%	501.62K	47.23M	-1.34M	-72.70%
Jun 30, 2025	PERCEPTIVE ADVISORS LLC	1%	708.18K	37.25M	17.69K	+2.56%
Jun 30, 2025	CORMORANT ASSET MANAGEMENT, LP	1.58%	1.12M	58.91M	380K	+51.35%
Jun 30, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	1.92%	1.37M	71.86M	112.1K	+8.94%
Jun 30, 2025	COMMODORE CAPITAL LP	4.96%	3.53M	185.42M	-947.84K	-21.19%
Jun 30, 2025	RTW INVESTMENTS, LP	5.63%	4M	210.43M	-168.84K	-4.05%
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	3.18%	2.26M	118.98M	1.17M	+106.44%
Jun 30, 2025	VANGUARD GROUP INC	0.37%	265.36K	13.96M	5.57K	+2.14%
Jun 30, 2025	OCTAGON CAPITAL ADVISORS LP	0.55%	389K	20.46M	81K	+26.30%
Jun 30, 2025	DARWIN GLOBAL MANAGEMENT, LTD.	0.56%	395.74K	20.97M	395.74K	+100.00%
Jun 30, 2025	DAFNA CAPITAL MANAGEMENT LLC	0.56%	398.8K	20.98M	-63K	-13.64%
Jun 30, 2025	SOFINNOVA INVESTMENTS, INC.	0.57%	404.56K	21.28M	404.56K	+100.00%
Jun 30, 2025	GILEAD SCIENCES, INC.	0.64%	452.53K	23.8M	0	0
Jun 30, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	4.76%	3.38M	178.03M	210.7K	+6.64%
Jun 30, 2025	BOXER CAPITAL MANAGEMENT, LLC	0.51%	365K	19.2M	-335K	-47.86%
Jun 30, 2025	CITADEL ADVISORS LLC	0.47%	335.59K	17.65B	308.61K	+1,143.45%
Jun 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	5.24%	3.73M	196.03M	-991.45K	-21.01%
Jun 30, 2025	PARADIGM BIOCAPITAL ADVISORS LP	6.02%	4.28M	225.23M	912.26K	+27.07%
Jun 30, 2025	FMR LLC	10.54%	7.49M	393.99M	523.46K	+7.51%
Jun 30, 2025	FRANKLIN RESOURCES INC	2.58%	1.84M	96.66M	-153.62K	-7.71%
Jun 30, 2025	HOLOCENE ADVISORS, LP	3.13%	2.23M	117.05M	351.62K	+18.77%
Jun 30, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	1.04%	741.97K	39.03M	-69.05K	-8.51%
Jun 30, 2025	NOVO HOLDINGS A/S	1.05%	750K	39.45M	-39.13K	-4.96%
Jun 30, 2025	SAMLYN CAPITAL, LLC	1.08%	765.19K	40.25M	-1.61M	-67.84%
Jun 30, 2025	JANUS HENDERSON GROUP PLC	1.17%	829.56K	43.61M	447.75K	+117.27%
Jun 30, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	0.64%	456.27K	24M	-53.5K	-10.49%
Jun 30, 2025	CAPITAL INTERNATIONAL INVESTORS	0.69%	491.24K	25.84M	491.24K	+100.00%
Jun 30, 2025	UBS GROUP AG	0.81%	577.69K	30.39M	-285.05K	-33.04%
Jun 30, 2025	TANG CAPITAL MANAGEMENT LLC	0.84%	600K	31.56M	500K	+500.00%
Jun 30, 2025	AVORO CAPITAL ADVISORS LLC	4.44%	3.16M	165.98M	155.56K	+5.19%
Jun 30, 2025	NAN FUNG TRINITY (HK) LTD	0.21%	150.34K	7.91M	150.34K	+100.00%
Jun 30, 2025	JPMORGAN CHASE & CO	0.97%	690.95K	36.34M	395.82K	+134.12%
Jun 30, 2025	INVESCO LTD.	1.17%	833.36K	43.83M	5.14K	+0.62%
Jun 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	1.17%	833.4K	43.84M	833.4K	+100.00%
Jun 30, 2025	SIREN, L.L.C.	1.2%	853.47K	44.89M	-190K	-18.21%
Jun 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	1.29%	915.25K	48.14M	-116.85K	-11.32%
Jun 30, 2025	BLACKROCK, INC.	1.48%	1.05M	55.28M	-640.93K	-37.88%
Jun 30, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	1.5%	1.06M	55.95M	82.86K	+8.45%
Jun 30, 2025	ARTIA GLOBAL PARTNERS LP	0.42%	296.75K	15.61M	-127.89K	-30.12%
Jun 30, 2025	DEEP TRACK CAPITAL, LP	0.39%	275K	14.47M	275K	+100.00%
Jun 30, 2025	TIMESSQUARE CAPITAL MANAGEMENT, LLC	0.34%	242.7K	12.77M	-101.01K	-29.39%
Jun 30, 2025	CAPTION MANAGEMENT, LLC	0.34%	240K	12.62M	210K	+700.00%
Jun 30, 2025	LORD, ABBETT & CO. LLC	0.32%	226K	11.89M	226K	+100.00%
Jun 30, 2025	PFM HEALTH SCIENCES, LP	0.26%	183.88K	9.67M	183.88K	+100.00%
Jun 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.24%	170.78K	8.98M	170.78K	+100.00%
Jun 30, 2025	PARKMAN HEALTHCARE PARTNERS LLC	0.23%	162.98K	8.57M	134.75K	+477.33%
Jun 30, 2025	FIRST TURN MANAGEMENT, LLC	0.41%	292.96K	15.41M	-171K	-36.86%
Jun 30, 2025	MORGAN STANLEY	0.65%	459.22K	24.15B	-344.37K	-42.85%
Jun 30, 2025	LYNX1 CAPITAL MANAGEMENT LP	2.21%	1.57M	82.52M	0	0
Jun 30, 2025	POLAR CAPITAL HOLDINGS PLC	2.27%	1.61M	84.74M	-95.81K	-5.61%
Jun 30, 2025	AMERIPRISE FINANCIAL INC	1.59%	1.13M	59.64M	1.03M	+1,007.28%
Jun 30, 2025	WOODLINE PARTNERS LP	2.17%	1.54M	81.16M	142.73K	+10.19%
Jun 30, 2025		0.51%	365K	19.2M	-335K	-47.86%
Jun 30, 2025	FEDERATED HERMES, INC.	2.15%	1.53M	80.4M	483.96K	+46.33%
Jun 30, 2025	STATE STREET CORP	0.34%	241.12K	12.68M	8.37K	+3.59%
Jun 30, 2025	WESTFIELD CAPITAL MANAGEMENT CO LP	2.87%	2.04M	107.43M	541.17K	+36.05%
Jun 30, 2025	IMPAX ASSET MANAGEMENT GROUP PLC	0.25%	180K	9.47M	0	0
Jun 30, 2025	DECHENG CAPITAL LLC	0.27%	189.1K	9.95M	0	0
Jun 30, 2025	CARMIGNAC GESTION	0.3%	214.72K	11.3M	93.56K	+77.22%
Jun 30, 2025	SATURN V CAPITAL MANAGEMENT LLC	0.32%	224.26K	11.8M	-98.95K	-30.62%
Jun 30, 2025	STEMPOINT CAPITAL LP	0.37%	266.09K	14M	-80.66K	-23.26%
Jun 30, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.38%	272.86K	14.35M	112.86K	+70.53%
Jun 30, 2025	BAKER BROS. ADVISORS LP	0.81%	574.38K	30.21M	350.88K	+156.99%
Jun 30, 2025	CALIGAN PARTNERS LP	0.92%	657K	34.56M	280.05K	+74.29%
Jun 30, 2025	ALLIANCEBERNSTEIN L.P.	1.55%	1.1M	57.98B	363.07K	+49.11%
Mar 31, 2025	PERCEPTIVE ADVISORS LLC	1%	690.49K	29.06M	390.49K	+130.16%
Mar 31, 2025	VANGUARD GROUP INC	0.38%	259.79K	10.93M	-1.84K	-0.70%
Mar 31, 2025	MARSHALL WACE, LLP	0.38%	259.77K	10.93M	-602.32K	-69.87%
Mar 31, 2025	AVORO CAPITAL ADVISORS LLC	4.35%	3M	126.27M	875K	+41.18%
Mar 31, 2025	SAMLYN CAPITAL, LLC	3.45%	2.38M	100.15M	-288.75K	-10.82%
Mar 31, 2025	FRANKLIN RESOURCES INC	2.89%	1.99M	83.81M	6.66K	+0.34%
Mar 31, 2025	HOLOCENE ADVISORS, LP	2.71%	1.87M	78.86M	-6.39K	-0.34%
Mar 31, 2025	POLAR CAPITAL HOLDINGS PLC	2.47%	1.71M	71.84M	624	+0.04%
Mar 31, 2025	FMR LLC	10.09%	6.97M	293.24M	67.39K	+0.98%
Mar 31, 2025	WESTFIELD CAPITAL MANAGEMENT CO LP	2.18%	1.5M	63.19M	508.06K	+51.16%
Mar 31, 2025	WOODLINE PARTNERS LP	2.03%	1.4M	58.93M	211.65K	+17.81%
Mar 31, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	1.82%	1.25M	52.79M	-26.19K	-2.05%
Mar 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.59%	1.1M	46.12M	-21.08K	-1.89%
Mar 31, 2025	FEDERATED HERMES, INC.	1.51%	1.04M	43.97M	-548.75K	-34.44%
Mar 31, 2025	SIREN, L.L.C.	1.51%	1.04M	43.92M	259.06K	+33.03%
Mar 31, 2025	UBS GROUP AG	1.25%	862.75K	36.31M	-244.69K	-22.10%
Mar 31, 2025	INVESCO LTD.	1.2%	828.22K	34.86M	41.85K	+5.32%
Mar 31, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	1.18%	811.02K	34.14M	130.18K	+19.12%
Mar 31, 2025	NOVO HOLDINGS A/S	1.14%	789.13K	33.21M	39.13K	+5.22%
Mar 31, 2025	CORMORANT ASSET MANAGEMENT, LP	1.07%	740K	31.15M	0	0
Mar 31, 2025	ALLIANCEBERNSTEIN L.P.	1.07%	739.29K	31.12M	-57.67K	-7.24%
Mar 31, 2025	CAPTION MANAGEMENT, LLC	0.39%	270K	11.36M	240K	+800.00%
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	0.85%	586.43K	24.68M	-297.13K	-33.63%
Mar 31, 2025	TWO SIGMA ADVISERS, LP	0.8%	554.4K	23.33M	-166.4K	-23.09%
Mar 31, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	0.74%	509.76K	21.46M	-298.82K	-36.96%
Mar 31, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	0.56%	385.82K	16.24M	73.5K	+23.53%
Mar 31, 2025	STEMPOINT CAPITAL LP	0.5%	346.76K	14.59M	-268.06K	-43.60%
Mar 31, 2025	TIMESSQUARE CAPITAL MANAGEMENT, LLC	0.5%	343.71K	14.47M	12.51K	+3.78%
Mar 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	6.84%	4.72M	198.59M	1.22M	+34.90%
Mar 31, 2025	COMMODORE CAPITAL LP	6.48%	4.47M	188.26M	598.66K	+15.45%
Mar 31, 2025	GREAT POINT PARTNERS LLC	0.34%	237.16K	9.98M	79.06K	+50.01%
Mar 31, 2025	RTW INVESTMENTS, LP	6.04%	4.17M	175.49M	0	0
Mar 31, 2025	PARADIGM BIOCAPITAL ADVISORS LP	4.88%	3.37M	141.83M	1.68M	+99.40%
Mar 31, 2025	GILEAD SCIENCES, INC.	0.66%	452.53K	19.05M	0	0
Mar 31, 2025	ARTIA GLOBAL PARTNERS LP	0.62%	424.64K	17.87M	-39.2K	-8.45%
Mar 31, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	0.54%	373.1K	15.7M	0	0
Mar 31, 2025	TWO SIGMA INVESTMENTS, LP	0.47%	325.86K	13.72M	-181.88K	-35.82%
Mar 31, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	4.6%	3.17M	133.59M	201.14K	+6.77%
Mar 31, 2025	BLACKROCK, INC.	2.45%	1.69M	71.21M	104.71K	+6.60%
Mar 31, 2025	LYNX1 CAPITAL MANAGEMENT LP	2.27%	1.57M	66.03M	-12K	-0.76%
Mar 31, 2025	DAFNA CAPITAL MANAGEMENT LLC	0.67%	461.8K	19.44M	10K	+2.21%
Mar 31, 2025	JANUS HENDERSON GROUP PLC	0.55%	381.81K	17M	360.52K	+1,693.38%
Mar 31, 2025	CALIGAN PARTNERS LP	0.55%	376.95K	15.87M	121.95K	+47.83%
Mar 31, 2025	SATURN V CAPITAL MANAGEMENT LLC	0.47%	323.21K	13.6M	88.57K	+37.75%
Mar 31, 2025	AFFINITY ASSET ADVISORS, LLC	0.47%	321.96K	13.55M	-67.28K	-17.28%
Mar 31, 2025	PICTET ASSET MANAGEMENT HOLDING SA	1.5%	1.03M	43.44M	274	+0.03%
Mar 31, 2025	JPMORGAN CHASE & CO	0.43%	295.12K	12.42M	269.94K	+1,072.05%
Mar 31, 2025	MORGAN STANLEY	1.16%	803.59K	33.82M	228.39K	+39.71%
Mar 31, 2025	OCTAGON CAPITAL ADVISORS LP	0.45%	308K	12.96M	0	0
Mar 31, 2025	FIRST TURN MANAGEMENT, LLC	0.67%	463.96K	19.53M	178.8K	+62.70%
Mar 31, 2024	LYNX1 CAPITAL MANAGEMENT LP	2.92%	1.51M	67.95M	373.78K	+32.93%
Mar 31, 2024	SPHERA FUNDS MANAGEMENT LTD.	0.29%	149.33K	6.72M	-81K	-35.17%
Mar 31, 2024	MILLENNIUM MANAGEMENT LLC	0.29%	150.27K	6.77M	-543.06K	-78.33%
Mar 31, 2024	TD ASSET MANAGEMENT INC	0.29%	151.17K	6.81M	151.17K	+100.00%
Mar 31, 2024	VANGUARD GROUP INC	0.3%	156.15K	7.03M	4.19K	+2.76%
Mar 31, 2024	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.32%	165K	7.43M	165K	+100.00%
Mar 31, 2024	SOLEUS CAPITAL MANAGEMENT, L.P.	0.38%	195.58K	8.81M	-107K	-35.36%
Mar 31, 2024	GREAT POINT PARTNERS LLC	0.43%	223.29K	10.05M	203.29K	+1,016.44%
Mar 31, 2024	STEMPOINT CAPITAL LP	0.45%	233.87K	10.53M	-267.94K	-53.39%
Mar 31, 2024	STATE STREET CORP	0.47%	244.68K	11.02M	8.99K	+3.81%
Mar 31, 2024	AQUILO CAPITAL MANAGEMENT, LLC	0.49%	255.11K	11.49M	-100K	-28.16%
Mar 31, 2024	ALLY BRIDGE GROUP (NY) LLC	0.5%	255.93K	11.52M	-19K	-6.91%
Mar 31, 2024	D. E. SHAW & CO., INC.	0.53%	273.53K	12.32M	214.49K	+363.34%
Mar 31, 2024	TRI LOCUM PARTNERS LP	0.55%	286.32K	12.89M	286.32K	+100.00%
Mar 31, 2024	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.63%	325K	14.63M	-5K	-1.52%
Mar 31, 2024	CITADEL ADVISORS LLC	0.68%	352.21K	15.86M	71.96K	+25.68%
Mar 31, 2024	WOODLINE PARTNERS LP	1.3%	670.8K	30.21M	427.57K	+175.79%
Mar 31, 2024	TWO SIGMA INVESTMENTS, LP	1.38%	712.11K	32.07M	397.06K	+126.03%
Mar 31, 2024	CORMORANT ASSET MANAGEMENT, LP	1.39%	715K	32.2M	715K	+100.00%
Mar 31, 2024	FAIRMOUNT FUNDS MANAGEMENT LLC	1.39%	717.25K	32.3M	0	0
Mar 31, 2024	TWO SIGMA ADVISERS, LP	1.39%	718.5K	32.35M	287K	+66.51%
Mar 31, 2024	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	1.41%	729.02K	32.83M	729.02K	+100.00%
Mar 31, 2024	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	1.45%	746.48K	33.61M	0	0
Mar 31, 2024	AVORO CAPITAL ADVISORS LLC	1.72%	888.89K	40.03M	0	0
Mar 31, 2024	HOLOCENE ADVISORS, LP	1.82%	939.58K	42.31M	939.58K	+100.00%
Mar 31, 2024	MORGAN STANLEY	1.89%	977.86K	44.03M	561.31K	+134.76%
Mar 31, 2024	ROCK SPRINGS CAPITAL MANAGEMENT LP	2.22%	1.15M	51.63M	274.49K	+31.48%
Mar 31, 2024	MEDICXI VENTURES MANAGEMENT (JERSEY) LTD	2.27%	1.17M	52.64M	-430.97K	-26.94%
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	2.3%	1.19M	53.38M	1.19M	+100.00%
Mar 31, 2024	DRIEHAUS CAPITAL MANAGEMENT LLC	2.38%	1.23M	55.23M	-84.52K	-6.45%
Mar 31, 2024	WELLINGTON MANAGEMENT GROUP LLP	2.42%	1.25M	56.23M	-760.76K	-37.86%
Mar 31, 2024	BLACKROCK INC.	2.84%	1.47M	66.1M	38.03K	+2.66%
Mar 31, 2024	SAMLYN CAPITAL, LLC	4.02%	2.08M	93.51M	-1.34M	-39.15%
Mar 31, 2024	FEDERATED HERMES, INC.	4.36%	2.25M	101.26M	-1.39M	-38.17%
Mar 31, 2024	SATURN V CAPITAL MANAGEMENT LLC	0.73%	376.63K	16.96M	-12.7K	-3.26%
Mar 31, 2024	DAFNA CAPITAL MANAGEMENT LLC	0.73%	379K	17.07M	-75.88K	-16.68%
Mar 31, 2024	ARTAL GROUP S.A.	0.88%	455.08K	20.49M	455.08K	+100.00%
Mar 31, 2024	JANUS HENDERSON GROUP PLC	1.05%	542.58K	24.43M	11.54K	+2.17%
Mar 31, 2024	5AM VENTURE MANAGEMENT, LLC	1.06%	548.83K	24.71M	27.29K	+5.23%
Mar 31, 2024	SILVERARC CAPITAL MANAGEMENT, LLC	1.1%	566.29K	25.5M	-79.29K	-12.28%
Mar 31, 2024	PICTET ASSET MANAGEMENT HOLDING SA	1.22%	629.68K	28.35M	-603.13K	-48.92%
Mar 31, 2024	ARIZONA STATE RETIREMENT SYSTEM	0.02%	10.31K	464.39K	14	+0.14%
Mar 31, 2024	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.02%	11.11K	500K	4.43K	+66.34%
Mar 31, 2024	ADVISOR GROUP HOLDINGS, INC.	0.02%	11.78K	530.45K	3.18K	+37.00%
Mar 31, 2024	HRT FINANCIAL LP	0.02%	12.39K	557K	-25.39K	-67.21%
Mar 31, 2024	VICTORY CAPITAL MANAGEMENT INC	0.02%	12.55K	565.13K	1.78K	+16.53%
Mar 31, 2024	SUSQUEHANNA PORTFOLIO STRATEGIES, LLC	0.04%	18.93K	852.6K	18.93K	+100.00%
Mar 31, 2024	STATE OF WISCONSIN INVESTMENT BOARD	0.04%	22.73K	1.02M	-2.89K	-11.27%
Mar 31, 2024	HEALTHINVEST PARTNERS AB	0.05%	24.33K	1.1M	0	0
Mar 31, 2024	SANDERS MORRIS HARRIS LLC	0.05%	24.87K	1.12M	0	0
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.06%	31.15K	1.4M	31.15K	+100.00%
Mar 31, 2024	LEGAL & GENERAL GROUP PLC	0.07%	34.62K	1.56B	0	0
Mar 31, 2024	CARMIGNAC GESTION	0.08%	39.17K	1.76M	-364.69K	-90.30%
Mar 31, 2024	SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC	0.08%	39.91K	1.8M	39.91K	+100.00%
Mar 31, 2024	ALPS ADVISORS INC	0.08%	40.83K	1.84M	700	+1.74%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.09%	46.57K	2.1M	2.9K	+6.63%
Mar 31, 2024	CREDIT SUISSE AG/	0.09%	48.69K	2.19M	3.7K	+8.23%
Mar 31, 2024	FIRST TRUST ADVISORS LP	0.1%	51.06K	2.3M	15.88K	+45.13%
Mar 31, 2024	NORTHERN TRUST CORP	0.1%	51.58K	2.32M	-3.06K	-5.60%
Mar 31, 2024	HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND	0.1%	52K	2.34M	52K	+100.00%
Mar 31, 2024	DEKABANK DEUTSCHE GIROZENTRALE	0.11%	56K	2.44M	0	0
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	0.11%	57.46K	2.59M	3.85K	+7.18%
Mar 31, 2024	STATE OF NEW JERSEY COMMON PENSION FUND D	0.11%	58.57K	2.64M	58.57K	+100.00%
Mar 31, 2024	TREXQUANT INVESTMENT LP	0.12%	63.56K	2.86M	23.07K	+56.97%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.14%	71.95K	3.24M	71.95K	+100.00%
Mar 31, 2024	SWISS NATIONAL BANK	0.14%	74.05K	3.33M	1.4K	+1.93%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.08%	41.7K	1.88M	41.7K	+100.00%
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	0.16%	83.26K	3.75M	-85.84K	-50.76%
Mar 31, 2024	NAN FUNG GROUP HOLDINGS LTD	0.17%	89.52K	4.03M	-47.52K	-34.68%
Mar 31, 2024	ALGERT GLOBAL LLC	0.19%	97.77K	4.4M	28.84K	+41.84%
Mar 31, 2024	PLATINUM INVESTMENT MANAGEMENT LTD	0.19%	99.49K	4.48M	-42.54K	-29.95%
Mar 31, 2024	DECHENG CAPITAL LLC	0.2%	101.8K	4.58M	101.8K	+100.00%
Mar 31, 2024	BNP PARIBAS ARBITRAGE, SNC	0.2%	102.89K	4.63M	40.06K	+63.76%
Mar 31, 2024	JPMORGAN CHASE & CO	0.21%	109.43K	4.93M	98.33K	+886.21%
Mar 31, 2024	ALTITUDE CREST PARTNERS INC.	0.21%	109.84K	4.95M	109.84K	+100.00%
Mar 31, 2024	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.24%	124.63K	5.61M	85.54K	+218.85%
Mar 31, 2024	BVF INC/IL	2.27%	1.17M	52.79M	-1.58M	-57.41%
Mar 31, 2024	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	5.13%	2.65M	119.3M	-370.5K	-12.27%
Mar 31, 2024	RTW INVESTMENTS, LP	7.96%	4.11M	185.05M	1.74M	+73.13%
Mar 31, 2024	COMMODORE CAPITAL LP	8.45%	4.36M	196.33M	-387.37K	-8.16%
Mar 31, 2024	INVESCO LTD.	0.25%	128.25K	5.78M	80.89K	+170.77%
Mar 31, 2024	FMR LLC	3.22%	1.66M	74.86M	932.09K	+127.60%
Mar 31, 2024	VR ADVISER, LLC	3.47%	1.79M	80.61M	-358K	-16.67%
Mar 31, 2024	FRANKLIN RESOURCES INC	3.63%	1.87M	84.35M	-9.84K	-0.52%
Mar 31, 2024	BOXER CAPITAL, LLC	3.68%	1.9M	85.56M	0	0
Dec 31, 2023	LYNX1 CAPITAL MANAGEMENT LP	2.11%	1.14M	31.22M	-15K	-1.30%
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	1.29%	693.33K	19.07M	64.13K	+10.19%
Dec 31, 2023	FAIRMOUNT FUNDS MANAGEMENT LLC	1.33%	717.25K	19.72M	-1.16M	-61.88%
Dec 31, 2023	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	1.39%	746.48K	20.53M	0	0
Dec 31, 2023	ROCK SPRINGS CAPITAL MANAGEMENT LP	1.62%	872.07K	23.98M	33.64K	+4.01%
Dec 31, 2023	FMR LLC	1.36%	730.45K	20.09M	-44.5K	-5.74%
Dec 31, 2023		0.93%	501.81K	13.8M	501.81K	+100.00%
Dec 31, 2023	BALYASNY ASSET MANAGEMENT L.P.	2.29%	1.23M	33.91M	372.88K	+43.34%
Dec 31, 2023	DRIEHAUS CAPITAL MANAGEMENT LLC	2.43%	1.31M	36.05M	175.82K	+15.49%
Dec 31, 2023	BLACKROCK INC.	2.65%	1.43M	39.32M	-36.04K	-2.46%
Dec 31, 2023	MEDICXI VENTURES MANAGEMENT (JERSEY) LTD	2.97%	1.6M	44M	0	0
Dec 31, 2023	FRANKLIN RESOURCES INC	3.5%	1.88M	51.79M	-8.84K	-0.47%
Dec 31, 2023	BOXER CAPITAL, LLC	3.53%	1.9M	52.25M	0	0
Dec 31, 2023	WELLINGTON MANAGEMENT GROUP LLP	3.73%	2.01M	55.26M	2.01M	+100.00%
Dec 31, 2023	VR ADVISER, LLC	3.99%	2.15M	59.08M	422K	+24.45%
Dec 31, 2023	RTW INVESTMENTS, LP	4.41%	2.37M	65.27M	376.86K	+18.87%
Dec 31, 2023	BVF INC/IL	5.11%	2.75M	75.69M	0	0
Dec 31, 2023	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	5.61%	3.02M	83.05M	-857.04K	-22.11%
Dec 31, 2023	SAMLYN CAPITAL, LLC	6.33%	3.41M	93.84M	155.89K	+4.79%
Dec 31, 2023	FEDERATED HERMES, INC.	6.75%	3.64M	100.03M	751.61K	+26.05%
Dec 31, 2023	COMMODORE CAPITAL LP	8.81%	4.75M	130.55M	319.3K	+7.21%
Dec 31, 2023	UBS OCONNOR LLC	0.23%	121.3K	3.34M	-30.81K	-20.25%
Dec 31, 2023	CUBIST SYSTEMATIC STRATEGIES, LLC	0.23%	126.51K	3.48M	126.51K	+100.00%
Dec 31, 2023	HIGHVISTA STRATEGIES LLC	0.25%	133.57K	3.67M	10.94K	+8.92%
Dec 31, 2023	NAN FUNG GROUP HOLDINGS LTD	0.25%	137.04K	3.77M	0	0
Dec 31, 2023	PLATINUM INVESTMENT MANAGEMENT LTD	0.26%	142.03K	3.91M	0	0
Dec 31, 2023	VANGUARD GROUP INC	0.28%	151.96K	4.18M	-27.09K	-15.13%
Dec 31, 2023	PARKMAN HEALTHCARE PARTNERS LLC	0.29%	157.82K	4.34M	27.08K	+20.72%
Dec 31, 2023	ALLIANCEBERNSTEIN L.P.	0.31%	169.1K	4.65M	-23.19K	-12.06%
Dec 31, 2023	SPHERA FUNDS MANAGEMENT LTD.	0.43%	230.33K	6.33M	-23K	-9.08%
Dec 31, 2023	STATE STREET CORP	0.44%	235.69K	6.48M	15.91K	+7.24%
Dec 31, 2023	WOODLINE PARTNERS LP	0.45%	243.23K	6.69M	0	0
Dec 31, 2023	ALLY BRIDGE GROUP (NY) LLC	0.51%	274.92K	7.56M	53.54K	+24.18%
Dec 31, 2023	CITADEL ADVISORS LLC	0.52%	280.25K	7.71M	277.07K	+8,699.09%
Dec 31, 2023	SOLEUS CAPITAL MANAGEMENT, L.P.	0.56%	302.58K	8.32M	-81.91K	-21.30%
Dec 31, 2023	TWO SIGMA INVESTMENTS, LP	0.58%	315.05K	8.66M	256.86K	+441.42%
Dec 31, 2023	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.61%	330K	9.08M	230K	+230.00%
Dec 31, 2023	AQUILO CAPITAL MANAGEMENT, LLC	0.66%	355.11K	9.77M	-75K	-17.44%
Dec 31, 2023	BRAIDWELL LP	0.69%	370.68K	10.19M	370.68K	+100.00%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.72%	386.94K	10.64M	180.97K	+87.86%
Dec 31, 2023	SATURN V CAPITAL MANAGEMENT LLC	0.72%	389.33K	10.71M	349.27K	+871.73%
Dec 31, 2023	AVORO CAPITAL ADVISORS LLC	1.65%	888.89K	24.44M	444.44K	+100.00%
Dec 31, 2023	CARMIGNAC GESTION	0.75%	403.86K	11.13M	-50.47K	-11.11%
Dec 31, 2023	MORGAN STANLEY	0.77%	416.54K	11.45M	69.65K	+20.08%
Dec 31, 2023	TWO SIGMA ADVISERS, LP	0.8%	431.5K	11.87M	212.4K	+96.94%
Dec 31, 2023	DAFNA CAPITAL MANAGEMENT LLC	0.84%	454.87K	12.51M	-30K	-6.19%
Dec 31, 2023	5AM VENTURE MANAGEMENT, LLC	0.97%	521.53K	14.34M	521.53K	+100.00%
Dec 31, 2023	JANUS HENDERSON GROUP PLC	0.99%	531.04K	14.6M	332.76K	+167.81%
Dec 31, 2023	SILVERARC CAPITAL MANAGEMENT, LLC	1.2%	645.58K	17.75M	145.58K	+29.12%

Insiders

Among the MRUS insiders holding of 2.29% of the stake in company, BVF PARTNERS L P/IL, 10 percent owner, holds the largest shares of 232.75K. THROSBY MARK, EVP & Chief Scientific Officer, is the second largest MRUS insider with ownership of 45.52K shares. LUNDBERG SVEN ANTE, President, CEO & PFO, stands third with possession of 40.58K shares of that stake.

Insiders	Designation	Shares Held
BVF PARTNERS L P/IL	10 percent owner	232.75K
THROSBY MARK	EVP & Chief Scientific Officer	45.52K
LUNDBERG SVEN ANTE	President, CEO & PFO	40.58K
DE KRUIF JOHN	SVP & Chief Technology Officer	15.28K
SHUMAN HARRY	VP Controller, PAO	11K
BAKKER LEX	SVP, Chief Development Officer	8.67K
GENMAB A/S	10 percent owner	0
SILVERMAN PETER B.	COO & GC	0

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Dec 29, 2025	GENMAB A/S	PURCHASE	97.00	75.87M	7.36B	0
Dec 26, 2025	GENMAB A/S	PURCHASE	97.00	2.98K	288.87K	72.83M
Dec 24, 2025	GENMAB A/S	PURCHASE	97.00	96.08K	9.32M	72.69M
Dec 23, 2025	GENMAB A/S	PURCHASE	97.00	561.04K	54.42M	72.59M
Dec 22, 2025	GENMAB A/S	PURCHASE	97.00	15.71K	1.52M	72.03M
Dec 19, 2025	GENMAB A/S	PURCHASE	97.00	66.26K	6.43M	72.01M
Dec 18, 2025	GENMAB A/S	PURCHASE	97.00	212.18K	20.58M	71.95M
Dec 17, 2025	GENMAB A/S	PURCHASE	97.00	150.8K	14.63M	71.73M
Dec 16, 2025	GENMAB A/S	PURCHASE	97.00	120.75K	11.71M	71.58M
Nov 26, 2025	SHUMAN HARRY	SALE	96.10	1.7K	163.37K	11K
Nov 25, 2025	SHUMAN HARRY	SALE	95.92	8.3K	796.14K	11K
Jul 17, 2025	SILVERMAN PETER B.	SALE	60.00	25K	1.5M	0
Jul 10, 2025	SILVERMAN PETER B.	SALE	55.00	16.81K	924.28K	0
Jun 20, 2025	SILVERMAN PETER B.	SALE	52.76	34K	1.79M	0
Mar 21, 2025	SHUMAN HARRY	SALE	48.55	1K	48.55K	11K
Aug 21, 2024	SHUMAN HARRY	SALE	54.00	2.5K	135K	7K
Jun 27, 2024	SILVERMAN PETER B.	SALE	60.00	10K	600K	0
Jun 17, 2024	SILVERMAN PETER B.	SALE	56.52	62K	3.5M	0
Jun 12, 2024	SHUMAN HARRY	SALE	57.84	7.3K	422.23K	7K
Jun 10, 2024	SHUMAN HARRY	SALE	53.22	1K	53.22K	7K
Jun 04, 2024	SHUMAN HARRY	SALE	53.12	1K	53.12K	7K
Dec 19, 2023	SHUMAN HARRY	SALE	26.68	115	3.07K	7K
Dec 15, 2023	SILVERMAN PETER B.	SALE	25.00	22.39K	559.65K	0
Dec 08, 2023	SHUMAN HARRY	SALE	24.44	250	6.11K	7.12K
Dec 01, 2023	SHUMAN HARRY	SALE	24.58	575	14.13K	7.37K
Jun 01, 2023	SHUMAN HARRY	SALE	21.48	575	12.35K	5.44K
Dec 13, 2022	SHUMAN HARRY	SALE	13.85	168	2.33K	3.52K
Dec 01, 2022	SHUMAN HARRY	SALE	15.35	575	8.83K	3.69K
Nov 03, 2022	LUNDBERG SVEN ANTE	PURCHASE	14.38	14.71K	211.43K	40.58K
Aug 25, 2022	SHUMAN HARRY	SALE	24.33	165	4.01K	1.76K
Aug 22, 2022	LUNDBERG SVEN ANTE	PURCHASE	22.92	5.83K	133.56K	25.87K
Aug 19, 2022	LUNDBERG SVEN ANTE	PURCHASE	22.99	704	16.19K	20.04K
Jul 12, 2022	LUNDBERG SVEN ANTE	PURCHASE	22.97	4.34K	99.68K	19.34K
Jun 01, 2022	SHUMAN HARRY	SALE	18.31	575	10.53K	1.93K
Mar 10, 2022	SILVERMAN PETER B.	SALE	26.95	60K	1.62M	0
Oct 08, 2021	BVF PARTNERS L P/IL	SALE	27.79	8.93K	248.11K	232.75K
Oct 07, 2021	BVF PARTNERS L P/IL	SALE	27.53	69.53K	1.91M	241.68K
Aug 12, 2021	DE KRUIF JOHN	SALE	19.34	2.79K	53.9K	15.28K
Jul 02, 2021	BVF PARTNERS L P/IL	SALE	20.75	150.81K	3.13M	311.21K
Jul 01, 2021	BAKKER LEX	SALE	21.00	560	11.76K	8.67K
Mar 30, 2021	BVF PARTNERS L P/IL	PURCHASE	19.75	26.89K	531.16K	462.02K
Mar 22, 2021	BVF PARTNERS L P/IL	PURCHASE	22.75	7.74K	176.18K	435.12K
Mar 16, 2021	BVF PARTNERS L P/IL	PURCHASE	23.00	1.17K	26.93K	427.38K
Jan 21, 2021	BVF PARTNERS L P/IL	PURCHASE	24.75	43.42K	1.07M	426.21K
Dec 18, 2020	BVF PARTNERS L P/IL	PURCHASE	16.05	45.03K	722.76K	2.25M
Sep 15, 2020	BVF PARTNERS L P/IL	PURCHASE	11.75	10.26K	120.53K	382.78K
Sep 10, 2020	BVF PARTNERS L P/IL	PURCHASE	11.10	12.82K	142.23K	372.53K
Sep 03, 2020	BVF PARTNERS L P/IL	PURCHASE	11.17	14.34K	160.17K	359.71K
Jul 07, 2020	THROSBY MARK	SALE	15.46	368	5.69K	45.52K
Jun 08, 2020	BVF PARTNERS L P/IL	PURCHASE	15.20	6.97K	105.9K	345.37K
Jun 02, 2020	THROSBY MARK	SALE	14.19	368	5.22K	45.18K
Jun 01, 2020	BVF PARTNERS L P/IL	PURCHASE	14.00	94.1K	1.32M	338.4K
May 06, 2020	THROSBY MARK	SALE	14.54	368	5.35K	44.84K
Apr 02, 2020	THROSBY MARK	SALE	10.93	368	4.02K	44.5K
Mar 04, 2020	THROSBY MARK	SALE	18.10	368	6.66K	44.16K
Feb 24, 2020	THROSBY MARK	SALE	17.74	57.09K	1.01M	43.82K
Feb 18, 2020	DE KRUIF JOHN	SALE	18.98	1.27K	24.07K	11.65K
Jan 16, 2020	BVF PARTNERS L P/IL	PURCHASE	16.15	19.73K	318.59K	244.3K
Jan 13, 2020	BVF PARTNERS L P/IL	PURCHASE	14.98	5.41K	80.97K	224.58K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE77.09M9

SALES10K2

NET SHARES77.08M7

SHARES HELD577.44M11

% NET SHARES-86.65%-36.36%

Frequently Asked Questions

Stock Outstanding Shares

ShortableNo

OptionableYes

Short Percent Of Outstanding Shares5.87

Short Percent Of Float5.9

Shares Outstanding75.63M

Shares Float65.61M

Shares Short4.44M

Short Ratio6.49

5.9%

Short % of Float

5.87%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

2.29% Percentage of Shares held by All Insiders

103.8% Percentage of Shares held by All Institutions

106.23% Percentage of Float held by Institutions

294

Number of Institutions Holding Shares

Institutional Ownership

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Sep 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.59%	417.4K	39.3M	314K	+303.68%
Sep 30, 2025	PERCEPTIVE ADVISORS LLC	1.9%	1.35M	127.39M	644.92K	+91.07%
Sep 30, 2025	ABSOLUTE GESTAO DE INVESTIMENTOS LTDA.	0.47%	330.59K	31.12M	330.59K	+100.00%
Sep 30, 2025	BANK OF MONTREAL /CAN/	0.08%	60.21K	5.67M	38.07K	+171.95%
Sep 30, 2025	TD ASSET MANAGEMENT INC	0.09%	62.58K	5.89M	-26.53K	-29.77%
Sep 30, 2025	HAP TRADING, LLC	0.09%	65K	21.13M	65K	+100.00%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.1%	68K	6.39M	7.05K	+11.56%
Sep 30, 2025	VESTCOR INC	0.1%	70K	6.59M	70K	+100.00%
Sep 30, 2025	FIRST TRUST ADVISORS LP	0.1%	72.99K	6.87M	72.99K	+100.00%
Sep 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0.11%	76.36K	7.19M	44.09K	+136.65%
Sep 30, 2025	MOODY ALDRICH PARTNERS LLC	0.11%	76.44K	7.2M	-15.57K	-16.92%
Sep 30, 2025	ATHOS CAPITAL LTD	0.11%	80K	7.53M	80K	+100.00%
Sep 30, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	0.84%	597.05K	56.21M	-466.56K	-43.87%
Sep 30, 2025	INVESCO LTD.	0.77%	548.52K	51.64M	-284.84K	-34.18%
Sep 30, 2025	SLOTNIK CAPITAL, LLC	0.13%	90K	8.47M	90K	+100.00%
Sep 30, 2025	CREDIT INDUSTRIEL ET COMMERCIAL	0.13%	90K	8.47M	90K	+100.00%
Sep 30, 2025	CITIGROUP INC	0.13%	95.22K	8.97M	60.72K	+175.96%
Sep 30, 2025	PICTON MAHONEY ASSET MANAGEMENT	0.14%	100K	9.42M	100K	+100.00%
Sep 30, 2025	SWISS NATIONAL BANK	0.14%	101.05K	9.51M	8.7K	+9.42%
Sep 30, 2025	GABELLI & CO INVESTMENT ADVISERS, INC.	0.15%	103.45K	9.74M	103.45K	+100.00%
Sep 30, 2025	DEUTSCHE BANK AG\	0.15%	104.11K	9.8M	-9.4K	-8.28%
Sep 30, 2025	GABELLI FUNDS LLC	0.15%	105.05K	9.89M	105.05K	+100.00%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.17%	121.78K	11.47M	-10.79K	-8.14%
Sep 30, 2025	VICTORY CAPITAL MANAGEMENT INC	0.18%	131.43K	12.37M	19.99K	+17.94%
Sep 30, 2025	BARCLAYS PLC	0.2%	144.04K	13.56M	110.39K	+328.14%
Sep 30, 2025	NAN FUNG TRINITY (HK) LTD	0.21%	150.34K	14.15M	0	0
Sep 30, 2025	ABRDN PLC	0.22%	155.15K	14.61M	29.38K	+23.36%
Sep 30, 2025	TIMESSQUARE CAPITAL MANAGEMENT, LLC	0.23%	166K	15.63M	-76.7K	-31.60%
Sep 30, 2025	CARMIGNAC GESTION	0.24%	167.53K	15.77M	-47.19K	-21.98%
Sep 30, 2025	ALLIANZ ASSET MANAGEMENT GMBH	0.27%	192.1K	18.09M	166.1K	+638.85%
Sep 30, 2025	HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND	0.27%	192.5K	18.12M	192.5K	+100.00%
Sep 30, 2025	TWIN SECURITIES, INC.	0.44%	310.26K	29.21M	310.26K	+100.00%
Sep 30, 2025	OCTAGON CAPITAL ADVISORS LP	0.43%	308K	29M	-81K	-20.82%
Sep 30, 2025	ARTIA GLOBAL PARTNERS LP	0.42%	296.75K	27.94M	0	0
Sep 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.4%	285.77K	26.91M	215.77K	+308.24%
Sep 30, 2025	VERSOR INVESTMENTS LP	0.28%	198.79K	18.72M	198.79K	+100.00%
Sep 30, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.3%	210.3K	19.8M	-23.17K	-9.92%
Sep 30, 2025	READYSTATE ASSET MANAGEMENT LP	0.34%	238.7K	22.47M	160.2K	+204.07%
Sep 30, 2025	VANGUARD GROUP INC	0.4%	282.88K	26.63M	17.52K	+6.60%
Sep 30, 2025	FIRST TURN MANAGEMENT, LLC	0.52%	372.02K	35.03M	79.06K	+26.99%
Sep 30, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.59%	422.28K	39.76M	418K	+9,777.82%
Sep 30, 2025	GILEAD SCIENCES, INC.	0.64%	452.53K	42.61M	0	0
Sep 30, 2025	VERITION FUND MANAGEMENT LLC	0.7%	498.9K	46.97M	494.92K	+12,444.63%
Sep 30, 2025	BAKER BROS. ADVISORS LP	0.81%	574.38K	54.08M	0	0
Sep 30, 2025	HUDSON BAY CAPITAL MANAGEMENT LP	1.04%	740.39K	69.71M	725.84K	+4,988.27%
Sep 30, 2025	NOVO HOLDINGS A/S	1.05%	750K	70.61M	0	0
Sep 30, 2025	JPMORGAN CHASE & CO	1.06%	756.01K	71.18M	65.07K	+9.42%
Sep 30, 2025	ALPINE ASSOCIATES MANAGEMENT INC.	1.18%	835.6K	78.67M	835.6K	+100.00%
Sep 30, 2025	AMERIPRISE FINANCIAL INC	1.26%	898.82K	84.62M	-235.04K	-20.73%
Sep 30, 2025	PENTWATER CAPITAL MANAGEMENT LP	1.36%	970K	91.33M	970K	+100.00%
Sep 30, 2025	MAGNETAR FINANCIAL LLC	1.47%	1.05M	98.41M	1.05M	+100.00%
Sep 30, 2025	KRYGER CAPITAL LTD	1.48%	1.05M	99.19M	1.05M	+100.00%
Sep 30, 2025	AVORO CAPITAL ADVISORS LLC	4.98%	3.54M	333.53M	386.95K	+12.26%
Sep 30, 2025	PARADIGM BIOCAPITAL ADVISORS LP	6.15%	4.37M	411.79M	91.82K	+2.14%
Sep 30, 2025	UBS GROUP AG	0.82%	581.07K	54.71M	3.38K	+0.58%
Sep 30, 2025	TUDOR INVESTMENT CORP ET AL	1.03%	731.15K	68.84M	731.15K	+100.00%
Sep 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.65%	459.09K	43.22M	-3.27M	-87.68%
Sep 30, 2025	JANUS HENDERSON GROUP PLC	0.93%	662.14K	62.33M	-167.42K	-20.18%
Sep 30, 2025	TIG ADVISORS, LLC	1.22%	868.15K	81.74M	868.15K	+100.00%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	1.68%	1.2M	112.55M	1.09M	+1,021.21%
Sep 30, 2025	ALLIANCEBERNSTEIN L.P.	1.68%	1.2M	112.63M	93.97K	+8.52%
Sep 30, 2025	FEDERATED HERMES, INC.	1.76%	1.25M	117.61M	-279.43K	-18.28%
Sep 30, 2025	LMR PARTNERS LLP	0.55%	390.47K	36.76M	390.47K	+100.00%
Sep 30, 2025	SOROS FUND MANAGEMENT LLC	0.57%	405K	38.13M	405K	+100.00%
Sep 30, 2025	TANG CAPITAL MANAGEMENT LLC	0.84%	600K	56.49M	0	0
Sep 30, 2025	FIL LTD	0.48%	338K	31.82M	338K	+100.00%
Sep 30, 2025	LYNX1 CAPITAL MANAGEMENT LP	2.16%	1.53M	144.44M	-34.7K	-2.21%
Sep 30, 2025	GLAZER CAPITAL, LLC	2.28%	1.62M	152.46M	1.62M	+100.00%
Sep 30, 2025	WOODLINE PARTNERS LP	2.35%	1.67M	157.62M	131.27K	+8.51%
Sep 30, 2025	RTW INVESTMENTS, LP	2.85%	2.03M	190.68M	-1.98M	-49.38%
Sep 30, 2025	WESTFIELD CAPITAL MANAGEMENT CO LP	3%	2.13M	200.77M	90.1K	+4.41%
Sep 30, 2025	BLACKROCK, INC.	3.06%	2.17M	204.5M	1.12M	+106.67%
Sep 30, 2025	FMR LLC	3.95%	2.81M	264.65M	-4.68M	-62.47%
Sep 30, 2025	HBK INVESTMENTS L P	4.01%	2.85M	268.33M	2.85M	+100.00%
Sep 30, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	4.29%	3.05M	286.87M	-337.71K	-9.98%
Sep 30, 2025	MILLENNIUM MANAGEMENT LLC	0.98%	699.03K	65.81M	683.23K	+4,325.35%
Sep 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.46%	330.23K	31.09M	-585.02K	-63.92%
Sep 30, 2025	MAN GROUP PLC	0.51%	361.7K	34.05M	361.7K	+100.00%
Sep 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.84%	600K	56.49M	-233.4K	-28.01%
Sep 30, 2025	CITADEL ADVISORS LLC	0.86%	614.54K	57.86M	278.94K	+83.12%
Sep 30, 2025	BALYASNY ASSET MANAGEMENT L.P.	0.91%	644.28K	60.66M	644.28K	+100.00%
Sep 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.53%	1.09M	102.36M	-1.17M	-51.94%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.44%	311.57K	29.33M	161.6K	+107.76%
Sep 30, 2025	DEKABANK DEUTSCHE GIROZENTRALE	0.08%	56K	5.13M	0	0
Sep 30, 2025	HIGHBRIDGE CAPITAL MANAGEMENT LLC	0.08%	58.61K	5.52M	58.61K	+100.00%
Sep 30, 2025	GROUPE LA FRANCAISE	0.08%	60K	5.65M	60K	+100.00%
Sep 30, 2025	COMMODORE CAPITAL LP	4.96%	3.53M	331.88M	0	0
Sep 30, 2025	FRANKLIN RESOURCES INC	0.71%	501.62K	47.23M	-1.34M	-72.70%
Jun 30, 2025	PERCEPTIVE ADVISORS LLC	1%	708.18K	37.25M	17.69K	+2.56%
Jun 30, 2025	CORMORANT ASSET MANAGEMENT, LP	1.58%	1.12M	58.91M	380K	+51.35%
Jun 30, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	1.92%	1.37M	71.86M	112.1K	+8.94%
Jun 30, 2025	COMMODORE CAPITAL LP	4.96%	3.53M	185.42M	-947.84K	-21.19%
Jun 30, 2025	RTW INVESTMENTS, LP	5.63%	4M	210.43M	-168.84K	-4.05%
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	3.18%	2.26M	118.98M	1.17M	+106.44%
Jun 30, 2025	VANGUARD GROUP INC	0.37%	265.36K	13.96M	5.57K	+2.14%
Jun 30, 2025	OCTAGON CAPITAL ADVISORS LP	0.55%	389K	20.46M	81K	+26.30%
Jun 30, 2025	DARWIN GLOBAL MANAGEMENT, LTD.	0.56%	395.74K	20.97M	395.74K	+100.00%
Jun 30, 2025	DAFNA CAPITAL MANAGEMENT LLC	0.56%	398.8K	20.98M	-63K	-13.64%
Jun 30, 2025	SOFINNOVA INVESTMENTS, INC.	0.57%	404.56K	21.28M	404.56K	+100.00%
Jun 30, 2025	GILEAD SCIENCES, INC.	0.64%	452.53K	23.8M	0	0
Jun 30, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	4.76%	3.38M	178.03M	210.7K	+6.64%
Jun 30, 2025	BOXER CAPITAL MANAGEMENT, LLC	0.51%	365K	19.2M	-335K	-47.86%
Jun 30, 2025	CITADEL ADVISORS LLC	0.47%	335.59K	17.65B	308.61K	+1,143.45%
Jun 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	5.24%	3.73M	196.03M	-991.45K	-21.01%
Jun 30, 2025	PARADIGM BIOCAPITAL ADVISORS LP	6.02%	4.28M	225.23M	912.26K	+27.07%
Jun 30, 2025	FMR LLC	10.54%	7.49M	393.99M	523.46K	+7.51%
Jun 30, 2025	FRANKLIN RESOURCES INC	2.58%	1.84M	96.66M	-153.62K	-7.71%
Jun 30, 2025	HOLOCENE ADVISORS, LP	3.13%	2.23M	117.05M	351.62K	+18.77%
Jun 30, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	1.04%	741.97K	39.03M	-69.05K	-8.51%
Jun 30, 2025	NOVO HOLDINGS A/S	1.05%	750K	39.45M	-39.13K	-4.96%
Jun 30, 2025	SAMLYN CAPITAL, LLC	1.08%	765.19K	40.25M	-1.61M	-67.84%
Jun 30, 2025	JANUS HENDERSON GROUP PLC	1.17%	829.56K	43.61M	447.75K	+117.27%
Jun 30, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	0.64%	456.27K	24M	-53.5K	-10.49%
Jun 30, 2025	CAPITAL INTERNATIONAL INVESTORS	0.69%	491.24K	25.84M	491.24K	+100.00%
Jun 30, 2025	UBS GROUP AG	0.81%	577.69K	30.39M	-285.05K	-33.04%
Jun 30, 2025	TANG CAPITAL MANAGEMENT LLC	0.84%	600K	31.56M	500K	+500.00%
Jun 30, 2025	AVORO CAPITAL ADVISORS LLC	4.44%	3.16M	165.98M	155.56K	+5.19%
Jun 30, 2025	NAN FUNG TRINITY (HK) LTD	0.21%	150.34K	7.91M	150.34K	+100.00%
Jun 30, 2025	JPMORGAN CHASE & CO	0.97%	690.95K	36.34M	395.82K	+134.12%
Jun 30, 2025	INVESCO LTD.	1.17%	833.36K	43.83M	5.14K	+0.62%
Jun 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	1.17%	833.4K	43.84M	833.4K	+100.00%
Jun 30, 2025	SIREN, L.L.C.	1.2%	853.47K	44.89M	-190K	-18.21%
Jun 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	1.29%	915.25K	48.14M	-116.85K	-11.32%
Jun 30, 2025	BLACKROCK, INC.	1.48%	1.05M	55.28M	-640.93K	-37.88%
Jun 30, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	1.5%	1.06M	55.95M	82.86K	+8.45%
Jun 30, 2025	ARTIA GLOBAL PARTNERS LP	0.42%	296.75K	15.61M	-127.89K	-30.12%
Jun 30, 2025	DEEP TRACK CAPITAL, LP	0.39%	275K	14.47M	275K	+100.00%
Jun 30, 2025	TIMESSQUARE CAPITAL MANAGEMENT, LLC	0.34%	242.7K	12.77M	-101.01K	-29.39%
Jun 30, 2025	CAPTION MANAGEMENT, LLC	0.34%	240K	12.62M	210K	+700.00%
Jun 30, 2025	LORD, ABBETT & CO. LLC	0.32%	226K	11.89M	226K	+100.00%
Jun 30, 2025	PFM HEALTH SCIENCES, LP	0.26%	183.88K	9.67M	183.88K	+100.00%
Jun 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.24%	170.78K	8.98M	170.78K	+100.00%
Jun 30, 2025	PARKMAN HEALTHCARE PARTNERS LLC	0.23%	162.98K	8.57M	134.75K	+477.33%
Jun 30, 2025	FIRST TURN MANAGEMENT, LLC	0.41%	292.96K	15.41M	-171K	-36.86%
Jun 30, 2025	MORGAN STANLEY	0.65%	459.22K	24.15B	-344.37K	-42.85%
Jun 30, 2025	LYNX1 CAPITAL MANAGEMENT LP	2.21%	1.57M	82.52M	0	0
Jun 30, 2025	POLAR CAPITAL HOLDINGS PLC	2.27%	1.61M	84.74M	-95.81K	-5.61%
Jun 30, 2025	AMERIPRISE FINANCIAL INC	1.59%	1.13M	59.64M	1.03M	+1,007.28%
Jun 30, 2025	WOODLINE PARTNERS LP	2.17%	1.54M	81.16M	142.73K	+10.19%
Jun 30, 2025		0.51%	365K	19.2M	-335K	-47.86%
Jun 30, 2025	FEDERATED HERMES, INC.	2.15%	1.53M	80.4M	483.96K	+46.33%
Jun 30, 2025	STATE STREET CORP	0.34%	241.12K	12.68M	8.37K	+3.59%
Jun 30, 2025	WESTFIELD CAPITAL MANAGEMENT CO LP	2.87%	2.04M	107.43M	541.17K	+36.05%
Jun 30, 2025	IMPAX ASSET MANAGEMENT GROUP PLC	0.25%	180K	9.47M	0	0
Jun 30, 2025	DECHENG CAPITAL LLC	0.27%	189.1K	9.95M	0	0
Jun 30, 2025	CARMIGNAC GESTION	0.3%	214.72K	11.3M	93.56K	+77.22%
Jun 30, 2025	SATURN V CAPITAL MANAGEMENT LLC	0.32%	224.26K	11.8M	-98.95K	-30.62%
Jun 30, 2025	STEMPOINT CAPITAL LP	0.37%	266.09K	14M	-80.66K	-23.26%
Jun 30, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.38%	272.86K	14.35M	112.86K	+70.53%
Jun 30, 2025	BAKER BROS. ADVISORS LP	0.81%	574.38K	30.21M	350.88K	+156.99%
Jun 30, 2025	CALIGAN PARTNERS LP	0.92%	657K	34.56M	280.05K	+74.29%
Jun 30, 2025	ALLIANCEBERNSTEIN L.P.	1.55%	1.1M	57.98B	363.07K	+49.11%
Mar 31, 2025	PERCEPTIVE ADVISORS LLC	1%	690.49K	29.06M	390.49K	+130.16%
Mar 31, 2025	VANGUARD GROUP INC	0.38%	259.79K	10.93M	-1.84K	-0.70%
Mar 31, 2025	MARSHALL WACE, LLP	0.38%	259.77K	10.93M	-602.32K	-69.87%
Mar 31, 2025	AVORO CAPITAL ADVISORS LLC	4.35%	3M	126.27M	875K	+41.18%
Mar 31, 2025	SAMLYN CAPITAL, LLC	3.45%	2.38M	100.15M	-288.75K	-10.82%
Mar 31, 2025	FRANKLIN RESOURCES INC	2.89%	1.99M	83.81M	6.66K	+0.34%
Mar 31, 2025	HOLOCENE ADVISORS, LP	2.71%	1.87M	78.86M	-6.39K	-0.34%
Mar 31, 2025	POLAR CAPITAL HOLDINGS PLC	2.47%	1.71M	71.84M	624	+0.04%
Mar 31, 2025	FMR LLC	10.09%	6.97M	293.24M	67.39K	+0.98%
Mar 31, 2025	WESTFIELD CAPITAL MANAGEMENT CO LP	2.18%	1.5M	63.19M	508.06K	+51.16%
Mar 31, 2025	WOODLINE PARTNERS LP	2.03%	1.4M	58.93M	211.65K	+17.81%
Mar 31, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	1.82%	1.25M	52.79M	-26.19K	-2.05%
Mar 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.59%	1.1M	46.12M	-21.08K	-1.89%
Mar 31, 2025	FEDERATED HERMES, INC.	1.51%	1.04M	43.97M	-548.75K	-34.44%
Mar 31, 2025	SIREN, L.L.C.	1.51%	1.04M	43.92M	259.06K	+33.03%
Mar 31, 2025	UBS GROUP AG	1.25%	862.75K	36.31M	-244.69K	-22.10%
Mar 31, 2025	INVESCO LTD.	1.2%	828.22K	34.86M	41.85K	+5.32%
Mar 31, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	1.18%	811.02K	34.14M	130.18K	+19.12%
Mar 31, 2025	NOVO HOLDINGS A/S	1.14%	789.13K	33.21M	39.13K	+5.22%
Mar 31, 2025	CORMORANT ASSET MANAGEMENT, LP	1.07%	740K	31.15M	0	0
Mar 31, 2025	ALLIANCEBERNSTEIN L.P.	1.07%	739.29K	31.12M	-57.67K	-7.24%
Mar 31, 2025	CAPTION MANAGEMENT, LLC	0.39%	270K	11.36M	240K	+800.00%
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	0.85%	586.43K	24.68M	-297.13K	-33.63%
Mar 31, 2025	TWO SIGMA ADVISERS, LP	0.8%	554.4K	23.33M	-166.4K	-23.09%
Mar 31, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	0.74%	509.76K	21.46M	-298.82K	-36.96%
Mar 31, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	0.56%	385.82K	16.24M	73.5K	+23.53%
Mar 31, 2025	STEMPOINT CAPITAL LP	0.5%	346.76K	14.59M	-268.06K	-43.60%
Mar 31, 2025	TIMESSQUARE CAPITAL MANAGEMENT, LLC	0.5%	343.71K	14.47M	12.51K	+3.78%
Mar 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	6.84%	4.72M	198.59M	1.22M	+34.90%
Mar 31, 2025	COMMODORE CAPITAL LP	6.48%	4.47M	188.26M	598.66K	+15.45%
Mar 31, 2025	GREAT POINT PARTNERS LLC	0.34%	237.16K	9.98M	79.06K	+50.01%
Mar 31, 2025	RTW INVESTMENTS, LP	6.04%	4.17M	175.49M	0	0
Mar 31, 2025	PARADIGM BIOCAPITAL ADVISORS LP	4.88%	3.37M	141.83M	1.68M	+99.40%
Mar 31, 2025	GILEAD SCIENCES, INC.	0.66%	452.53K	19.05M	0	0
Mar 31, 2025	ARTIA GLOBAL PARTNERS LP	0.62%	424.64K	17.87M	-39.2K	-8.45%
Mar 31, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	0.54%	373.1K	15.7M	0	0
Mar 31, 2025	TWO SIGMA INVESTMENTS, LP	0.47%	325.86K	13.72M	-181.88K	-35.82%
Mar 31, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	4.6%	3.17M	133.59M	201.14K	+6.77%
Mar 31, 2025	BLACKROCK, INC.	2.45%	1.69M	71.21M	104.71K	+6.60%
Mar 31, 2025	LYNX1 CAPITAL MANAGEMENT LP	2.27%	1.57M	66.03M	-12K	-0.76%
Mar 31, 2025	DAFNA CAPITAL MANAGEMENT LLC	0.67%	461.8K	19.44M	10K	+2.21%
Mar 31, 2025	JANUS HENDERSON GROUP PLC	0.55%	381.81K	17M	360.52K	+1,693.38%
Mar 31, 2025	CALIGAN PARTNERS LP	0.55%	376.95K	15.87M	121.95K	+47.83%
Mar 31, 2025	SATURN V CAPITAL MANAGEMENT LLC	0.47%	323.21K	13.6M	88.57K	+37.75%
Mar 31, 2025	AFFINITY ASSET ADVISORS, LLC	0.47%	321.96K	13.55M	-67.28K	-17.28%
Mar 31, 2025	PICTET ASSET MANAGEMENT HOLDING SA	1.5%	1.03M	43.44M	274	+0.03%
Mar 31, 2025	JPMORGAN CHASE & CO	0.43%	295.12K	12.42M	269.94K	+1,072.05%
Mar 31, 2025	MORGAN STANLEY	1.16%	803.59K	33.82M	228.39K	+39.71%
Mar 31, 2025	OCTAGON CAPITAL ADVISORS LP	0.45%	308K	12.96M	0	0
Mar 31, 2025	FIRST TURN MANAGEMENT, LLC	0.67%	463.96K	19.53M	178.8K	+62.70%
Mar 31, 2024	LYNX1 CAPITAL MANAGEMENT LP	2.92%	1.51M	67.95M	373.78K	+32.93%
Mar 31, 2024	SPHERA FUNDS MANAGEMENT LTD.	0.29%	149.33K	6.72M	-81K	-35.17%
Mar 31, 2024	MILLENNIUM MANAGEMENT LLC	0.29%	150.27K	6.77M	-543.06K	-78.33%
Mar 31, 2024	TD ASSET MANAGEMENT INC	0.29%	151.17K	6.81M	151.17K	+100.00%
Mar 31, 2024	VANGUARD GROUP INC	0.3%	156.15K	7.03M	4.19K	+2.76%
Mar 31, 2024	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.32%	165K	7.43M	165K	+100.00%
Mar 31, 2024	SOLEUS CAPITAL MANAGEMENT, L.P.	0.38%	195.58K	8.81M	-107K	-35.36%
Mar 31, 2024	GREAT POINT PARTNERS LLC	0.43%	223.29K	10.05M	203.29K	+1,016.44%
Mar 31, 2024	STEMPOINT CAPITAL LP	0.45%	233.87K	10.53M	-267.94K	-53.39%
Mar 31, 2024	STATE STREET CORP	0.47%	244.68K	11.02M	8.99K	+3.81%
Mar 31, 2024	AQUILO CAPITAL MANAGEMENT, LLC	0.49%	255.11K	11.49M	-100K	-28.16%
Mar 31, 2024	ALLY BRIDGE GROUP (NY) LLC	0.5%	255.93K	11.52M	-19K	-6.91%
Mar 31, 2024	D. E. SHAW & CO., INC.	0.53%	273.53K	12.32M	214.49K	+363.34%
Mar 31, 2024	TRI LOCUM PARTNERS LP	0.55%	286.32K	12.89M	286.32K	+100.00%
Mar 31, 2024	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.63%	325K	14.63M	-5K	-1.52%
Mar 31, 2024	CITADEL ADVISORS LLC	0.68%	352.21K	15.86M	71.96K	+25.68%
Mar 31, 2024	WOODLINE PARTNERS LP	1.3%	670.8K	30.21M	427.57K	+175.79%
Mar 31, 2024	TWO SIGMA INVESTMENTS, LP	1.38%	712.11K	32.07M	397.06K	+126.03%
Mar 31, 2024	CORMORANT ASSET MANAGEMENT, LP	1.39%	715K	32.2M	715K	+100.00%
Mar 31, 2024	FAIRMOUNT FUNDS MANAGEMENT LLC	1.39%	717.25K	32.3M	0	0
Mar 31, 2024	TWO SIGMA ADVISERS, LP	1.39%	718.5K	32.35M	287K	+66.51%
Mar 31, 2024	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	1.41%	729.02K	32.83M	729.02K	+100.00%
Mar 31, 2024	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	1.45%	746.48K	33.61M	0	0
Mar 31, 2024	AVORO CAPITAL ADVISORS LLC	1.72%	888.89K	40.03M	0	0
Mar 31, 2024	HOLOCENE ADVISORS, LP	1.82%	939.58K	42.31M	939.58K	+100.00%
Mar 31, 2024	MORGAN STANLEY	1.89%	977.86K	44.03M	561.31K	+134.76%
Mar 31, 2024	ROCK SPRINGS CAPITAL MANAGEMENT LP	2.22%	1.15M	51.63M	274.49K	+31.48%
Mar 31, 2024	MEDICXI VENTURES MANAGEMENT (JERSEY) LTD	2.27%	1.17M	52.64M	-430.97K	-26.94%
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	2.3%	1.19M	53.38M	1.19M	+100.00%
Mar 31, 2024	DRIEHAUS CAPITAL MANAGEMENT LLC	2.38%	1.23M	55.23M	-84.52K	-6.45%
Mar 31, 2024	WELLINGTON MANAGEMENT GROUP LLP	2.42%	1.25M	56.23M	-760.76K	-37.86%
Mar 31, 2024	BLACKROCK INC.	2.84%	1.47M	66.1M	38.03K	+2.66%
Mar 31, 2024	SAMLYN CAPITAL, LLC	4.02%	2.08M	93.51M	-1.34M	-39.15%
Mar 31, 2024	FEDERATED HERMES, INC.	4.36%	2.25M	101.26M	-1.39M	-38.17%
Mar 31, 2024	SATURN V CAPITAL MANAGEMENT LLC	0.73%	376.63K	16.96M	-12.7K	-3.26%
Mar 31, 2024	DAFNA CAPITAL MANAGEMENT LLC	0.73%	379K	17.07M	-75.88K	-16.68%
Mar 31, 2024	ARTAL GROUP S.A.	0.88%	455.08K	20.49M	455.08K	+100.00%
Mar 31, 2024	JANUS HENDERSON GROUP PLC	1.05%	542.58K	24.43M	11.54K	+2.17%
Mar 31, 2024	5AM VENTURE MANAGEMENT, LLC	1.06%	548.83K	24.71M	27.29K	+5.23%
Mar 31, 2024	SILVERARC CAPITAL MANAGEMENT, LLC	1.1%	566.29K	25.5M	-79.29K	-12.28%
Mar 31, 2024	PICTET ASSET MANAGEMENT HOLDING SA	1.22%	629.68K	28.35M	-603.13K	-48.92%
Mar 31, 2024	ARIZONA STATE RETIREMENT SYSTEM	0.02%	10.31K	464.39K	14	+0.14%
Mar 31, 2024	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.02%	11.11K	500K	4.43K	+66.34%
Mar 31, 2024	ADVISOR GROUP HOLDINGS, INC.	0.02%	11.78K	530.45K	3.18K	+37.00%
Mar 31, 2024	HRT FINANCIAL LP	0.02%	12.39K	557K	-25.39K	-67.21%
Mar 31, 2024	VICTORY CAPITAL MANAGEMENT INC	0.02%	12.55K	565.13K	1.78K	+16.53%
Mar 31, 2024	SUSQUEHANNA PORTFOLIO STRATEGIES, LLC	0.04%	18.93K	852.6K	18.93K	+100.00%
Mar 31, 2024	STATE OF WISCONSIN INVESTMENT BOARD	0.04%	22.73K	1.02M	-2.89K	-11.27%
Mar 31, 2024	HEALTHINVEST PARTNERS AB	0.05%	24.33K	1.1M	0	0
Mar 31, 2024	SANDERS MORRIS HARRIS LLC	0.05%	24.87K	1.12M	0	0
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.06%	31.15K	1.4M	31.15K	+100.00%
Mar 31, 2024	LEGAL & GENERAL GROUP PLC	0.07%	34.62K	1.56B	0	0
Mar 31, 2024	CARMIGNAC GESTION	0.08%	39.17K	1.76M	-364.69K	-90.30%
Mar 31, 2024	SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC	0.08%	39.91K	1.8M	39.91K	+100.00%
Mar 31, 2024	ALPS ADVISORS INC	0.08%	40.83K	1.84M	700	+1.74%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.09%	46.57K	2.1M	2.9K	+6.63%
Mar 31, 2024	CREDIT SUISSE AG/	0.09%	48.69K	2.19M	3.7K	+8.23%
Mar 31, 2024	FIRST TRUST ADVISORS LP	0.1%	51.06K	2.3M	15.88K	+45.13%
Mar 31, 2024	NORTHERN TRUST CORP	0.1%	51.58K	2.32M	-3.06K	-5.60%
Mar 31, 2024	HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND	0.1%	52K	2.34M	52K	+100.00%
Mar 31, 2024	DEKABANK DEUTSCHE GIROZENTRALE	0.11%	56K	2.44M	0	0
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	0.11%	57.46K	2.59M	3.85K	+7.18%
Mar 31, 2024	STATE OF NEW JERSEY COMMON PENSION FUND D	0.11%	58.57K	2.64M	58.57K	+100.00%
Mar 31, 2024	TREXQUANT INVESTMENT LP	0.12%	63.56K	2.86M	23.07K	+56.97%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.14%	71.95K	3.24M	71.95K	+100.00%
Mar 31, 2024	SWISS NATIONAL BANK	0.14%	74.05K	3.33M	1.4K	+1.93%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.08%	41.7K	1.88M	41.7K	+100.00%
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	0.16%	83.26K	3.75M	-85.84K	-50.76%
Mar 31, 2024	NAN FUNG GROUP HOLDINGS LTD	0.17%	89.52K	4.03M	-47.52K	-34.68%
Mar 31, 2024	ALGERT GLOBAL LLC	0.19%	97.77K	4.4M	28.84K	+41.84%
Mar 31, 2024	PLATINUM INVESTMENT MANAGEMENT LTD	0.19%	99.49K	4.48M	-42.54K	-29.95%
Mar 31, 2024	DECHENG CAPITAL LLC	0.2%	101.8K	4.58M	101.8K	+100.00%
Mar 31, 2024	BNP PARIBAS ARBITRAGE, SNC	0.2%	102.89K	4.63M	40.06K	+63.76%
Mar 31, 2024	JPMORGAN CHASE & CO	0.21%	109.43K	4.93M	98.33K	+886.21%
Mar 31, 2024	ALTITUDE CREST PARTNERS INC.	0.21%	109.84K	4.95M	109.84K	+100.00%
Mar 31, 2024	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.24%	124.63K	5.61M	85.54K	+218.85%
Mar 31, 2024	BVF INC/IL	2.27%	1.17M	52.79M	-1.58M	-57.41%
Mar 31, 2024	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	5.13%	2.65M	119.3M	-370.5K	-12.27%
Mar 31, 2024	RTW INVESTMENTS, LP	7.96%	4.11M	185.05M	1.74M	+73.13%
Mar 31, 2024	COMMODORE CAPITAL LP	8.45%	4.36M	196.33M	-387.37K	-8.16%
Mar 31, 2024	INVESCO LTD.	0.25%	128.25K	5.78M	80.89K	+170.77%
Mar 31, 2024	FMR LLC	3.22%	1.66M	74.86M	932.09K	+127.60%
Mar 31, 2024	VR ADVISER, LLC	3.47%	1.79M	80.61M	-358K	-16.67%
Mar 31, 2024	FRANKLIN RESOURCES INC	3.63%	1.87M	84.35M	-9.84K	-0.52%
Mar 31, 2024	BOXER CAPITAL, LLC	3.68%	1.9M	85.56M	0	0
Dec 31, 2023	LYNX1 CAPITAL MANAGEMENT LP	2.11%	1.14M	31.22M	-15K	-1.30%
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	1.29%	693.33K	19.07M	64.13K	+10.19%
Dec 31, 2023	FAIRMOUNT FUNDS MANAGEMENT LLC	1.33%	717.25K	19.72M	-1.16M	-61.88%
Dec 31, 2023	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	1.39%	746.48K	20.53M	0	0
Dec 31, 2023	ROCK SPRINGS CAPITAL MANAGEMENT LP	1.62%	872.07K	23.98M	33.64K	+4.01%
Dec 31, 2023	FMR LLC	1.36%	730.45K	20.09M	-44.5K	-5.74%
Dec 31, 2023		0.93%	501.81K	13.8M	501.81K	+100.00%
Dec 31, 2023	BALYASNY ASSET MANAGEMENT L.P.	2.29%	1.23M	33.91M	372.88K	+43.34%
Dec 31, 2023	DRIEHAUS CAPITAL MANAGEMENT LLC	2.43%	1.31M	36.05M	175.82K	+15.49%
Dec 31, 2023	BLACKROCK INC.	2.65%	1.43M	39.32M	-36.04K	-2.46%
Dec 31, 2023	MEDICXI VENTURES MANAGEMENT (JERSEY) LTD	2.97%	1.6M	44M	0	0
Dec 31, 2023	FRANKLIN RESOURCES INC	3.5%	1.88M	51.79M	-8.84K	-0.47%
Dec 31, 2023	BOXER CAPITAL, LLC	3.53%	1.9M	52.25M	0	0
Dec 31, 2023	WELLINGTON MANAGEMENT GROUP LLP	3.73%	2.01M	55.26M	2.01M	+100.00%
Dec 31, 2023	VR ADVISER, LLC	3.99%	2.15M	59.08M	422K	+24.45%
Dec 31, 2023	RTW INVESTMENTS, LP	4.41%	2.37M	65.27M	376.86K	+18.87%
Dec 31, 2023	BVF INC/IL	5.11%	2.75M	75.69M	0	0
Dec 31, 2023	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	5.61%	3.02M	83.05M	-857.04K	-22.11%
Dec 31, 2023	SAMLYN CAPITAL, LLC	6.33%	3.41M	93.84M	155.89K	+4.79%
Dec 31, 2023	FEDERATED HERMES, INC.	6.75%	3.64M	100.03M	751.61K	+26.05%
Dec 31, 2023	COMMODORE CAPITAL LP	8.81%	4.75M	130.55M	319.3K	+7.21%
Dec 31, 2023	UBS OCONNOR LLC	0.23%	121.3K	3.34M	-30.81K	-20.25%
Dec 31, 2023	CUBIST SYSTEMATIC STRATEGIES, LLC	0.23%	126.51K	3.48M	126.51K	+100.00%
Dec 31, 2023	HIGHVISTA STRATEGIES LLC	0.25%	133.57K	3.67M	10.94K	+8.92%
Dec 31, 2023	NAN FUNG GROUP HOLDINGS LTD	0.25%	137.04K	3.77M	0	0
Dec 31, 2023	PLATINUM INVESTMENT MANAGEMENT LTD	0.26%	142.03K	3.91M	0	0
Dec 31, 2023	VANGUARD GROUP INC	0.28%	151.96K	4.18M	-27.09K	-15.13%
Dec 31, 2023	PARKMAN HEALTHCARE PARTNERS LLC	0.29%	157.82K	4.34M	27.08K	+20.72%
Dec 31, 2023	ALLIANCEBERNSTEIN L.P.	0.31%	169.1K	4.65M	-23.19K	-12.06%
Dec 31, 2023	SPHERA FUNDS MANAGEMENT LTD.	0.43%	230.33K	6.33M	-23K	-9.08%
Dec 31, 2023	STATE STREET CORP	0.44%	235.69K	6.48M	15.91K	+7.24%
Dec 31, 2023	WOODLINE PARTNERS LP	0.45%	243.23K	6.69M	0	0
Dec 31, 2023	ALLY BRIDGE GROUP (NY) LLC	0.51%	274.92K	7.56M	53.54K	+24.18%
Dec 31, 2023	CITADEL ADVISORS LLC	0.52%	280.25K	7.71M	277.07K	+8,699.09%
Dec 31, 2023	SOLEUS CAPITAL MANAGEMENT, L.P.	0.56%	302.58K	8.32M	-81.91K	-21.30%
Dec 31, 2023	TWO SIGMA INVESTMENTS, LP	0.58%	315.05K	8.66M	256.86K	+441.42%
Dec 31, 2023	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.61%	330K	9.08M	230K	+230.00%
Dec 31, 2023	AQUILO CAPITAL MANAGEMENT, LLC	0.66%	355.11K	9.77M	-75K	-17.44%
Dec 31, 2023	BRAIDWELL LP	0.69%	370.68K	10.19M	370.68K	+100.00%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.72%	386.94K	10.64M	180.97K	+87.86%
Dec 31, 2023	SATURN V CAPITAL MANAGEMENT LLC	0.72%	389.33K	10.71M	349.27K	+871.73%
Dec 31, 2023	AVORO CAPITAL ADVISORS LLC	1.65%	888.89K	24.44M	444.44K	+100.00%
Dec 31, 2023	CARMIGNAC GESTION	0.75%	403.86K	11.13M	-50.47K	-11.11%
Dec 31, 2023	MORGAN STANLEY	0.77%	416.54K	11.45M	69.65K	+20.08%
Dec 31, 2023	TWO SIGMA ADVISERS, LP	0.8%	431.5K	11.87M	212.4K	+96.94%
Dec 31, 2023	DAFNA CAPITAL MANAGEMENT LLC	0.84%	454.87K	12.51M	-30K	-6.19%
Dec 31, 2023	5AM VENTURE MANAGEMENT, LLC	0.97%	521.53K	14.34M	521.53K	+100.00%
Dec 31, 2023	JANUS HENDERSON GROUP PLC	0.99%	531.04K	14.6M	332.76K	+167.81%
Dec 31, 2023	SILVERARC CAPITAL MANAGEMENT, LLC	1.2%	645.58K	17.75M	145.58K	+29.12%

Insiders

Insiders	Designation	Shares Held
BVF PARTNERS L P/IL	10 percent owner	232.75K
THROSBY MARK	EVP & Chief Scientific Officer	45.52K
LUNDBERG SVEN ANTE	President, CEO & PFO	40.58K
DE KRUIF JOHN	SVP & Chief Technology Officer	15.28K
SHUMAN HARRY	VP Controller, PAO	11K
BAKKER LEX	SVP, Chief Development Officer	8.67K
GENMAB A/S	10 percent owner	0
SILVERMAN PETER B.	COO & GC	0

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Dec 29, 2025	GENMAB A/S	PURCHASE	97.00	75.87M	7.36B	0
Dec 26, 2025	GENMAB A/S	PURCHASE	97.00	2.98K	288.87K	72.83M
Dec 24, 2025	GENMAB A/S	PURCHASE	97.00	96.08K	9.32M	72.69M
Dec 23, 2025	GENMAB A/S	PURCHASE	97.00	561.04K	54.42M	72.59M
Dec 22, 2025	GENMAB A/S	PURCHASE	97.00	15.71K	1.52M	72.03M
Dec 19, 2025	GENMAB A/S	PURCHASE	97.00	66.26K	6.43M	72.01M
Dec 18, 2025	GENMAB A/S	PURCHASE	97.00	212.18K	20.58M	71.95M
Dec 17, 2025	GENMAB A/S	PURCHASE	97.00	150.8K	14.63M	71.73M
Dec 16, 2025	GENMAB A/S	PURCHASE	97.00	120.75K	11.71M	71.58M
Nov 26, 2025	SHUMAN HARRY	SALE	96.10	1.7K	163.37K	11K
Nov 25, 2025	SHUMAN HARRY	SALE	95.92	8.3K	796.14K	11K
Jul 17, 2025	SILVERMAN PETER B.	SALE	60.00	25K	1.5M	0
Jul 10, 2025	SILVERMAN PETER B.	SALE	55.00	16.81K	924.28K	0
Jun 20, 2025	SILVERMAN PETER B.	SALE	52.76	34K	1.79M	0
Mar 21, 2025	SHUMAN HARRY	SALE	48.55	1K	48.55K	11K
Aug 21, 2024	SHUMAN HARRY	SALE	54.00	2.5K	135K	7K
Jun 27, 2024	SILVERMAN PETER B.	SALE	60.00	10K	600K	0
Jun 17, 2024	SILVERMAN PETER B.	SALE	56.52	62K	3.5M	0
Jun 12, 2024	SHUMAN HARRY	SALE	57.84	7.3K	422.23K	7K
Jun 10, 2024	SHUMAN HARRY	SALE	53.22	1K	53.22K	7K
Jun 04, 2024	SHUMAN HARRY	SALE	53.12	1K	53.12K	7K
Dec 19, 2023	SHUMAN HARRY	SALE	26.68	115	3.07K	7K
Dec 15, 2023	SILVERMAN PETER B.	SALE	25.00	22.39K	559.65K	0
Dec 08, 2023	SHUMAN HARRY	SALE	24.44	250	6.11K	7.12K
Dec 01, 2023	SHUMAN HARRY	SALE	24.58	575	14.13K	7.37K
Jun 01, 2023	SHUMAN HARRY	SALE	21.48	575	12.35K	5.44K
Dec 13, 2022	SHUMAN HARRY	SALE	13.85	168	2.33K	3.52K
Dec 01, 2022	SHUMAN HARRY	SALE	15.35	575	8.83K	3.69K
Nov 03, 2022	LUNDBERG SVEN ANTE	PURCHASE	14.38	14.71K	211.43K	40.58K
Aug 25, 2022	SHUMAN HARRY	SALE	24.33	165	4.01K	1.76K
Aug 22, 2022	LUNDBERG SVEN ANTE	PURCHASE	22.92	5.83K	133.56K	25.87K
Aug 19, 2022	LUNDBERG SVEN ANTE	PURCHASE	22.99	704	16.19K	20.04K
Jul 12, 2022	LUNDBERG SVEN ANTE	PURCHASE	22.97	4.34K	99.68K	19.34K
Jun 01, 2022	SHUMAN HARRY	SALE	18.31	575	10.53K	1.93K
Mar 10, 2022	SILVERMAN PETER B.	SALE	26.95	60K	1.62M	0
Oct 08, 2021	BVF PARTNERS L P/IL	SALE	27.79	8.93K	248.11K	232.75K
Oct 07, 2021	BVF PARTNERS L P/IL	SALE	27.53	69.53K	1.91M	241.68K
Aug 12, 2021	DE KRUIF JOHN	SALE	19.34	2.79K	53.9K	15.28K
Jul 02, 2021	BVF PARTNERS L P/IL	SALE	20.75	150.81K	3.13M	311.21K
Jul 01, 2021	BAKKER LEX	SALE	21.00	560	11.76K	8.67K
Mar 30, 2021	BVF PARTNERS L P/IL	PURCHASE	19.75	26.89K	531.16K	462.02K
Mar 22, 2021	BVF PARTNERS L P/IL	PURCHASE	22.75	7.74K	176.18K	435.12K
Mar 16, 2021	BVF PARTNERS L P/IL	PURCHASE	23.00	1.17K	26.93K	427.38K
Jan 21, 2021	BVF PARTNERS L P/IL	PURCHASE	24.75	43.42K	1.07M	426.21K
Dec 18, 2020	BVF PARTNERS L P/IL	PURCHASE	16.05	45.03K	722.76K	2.25M
Sep 15, 2020	BVF PARTNERS L P/IL	PURCHASE	11.75	10.26K	120.53K	382.78K
Sep 10, 2020	BVF PARTNERS L P/IL	PURCHASE	11.10	12.82K	142.23K	372.53K
Sep 03, 2020	BVF PARTNERS L P/IL	PURCHASE	11.17	14.34K	160.17K	359.71K
Jul 07, 2020	THROSBY MARK	SALE	15.46	368	5.69K	45.52K
Jun 08, 2020	BVF PARTNERS L P/IL	PURCHASE	15.20	6.97K	105.9K	345.37K
Jun 02, 2020	THROSBY MARK	SALE	14.19	368	5.22K	45.18K
Jun 01, 2020	BVF PARTNERS L P/IL	PURCHASE	14.00	94.1K	1.32M	338.4K
May 06, 2020	THROSBY MARK	SALE	14.54	368	5.35K	44.84K
Apr 02, 2020	THROSBY MARK	SALE	10.93	368	4.02K	44.5K
Mar 04, 2020	THROSBY MARK	SALE	18.10	368	6.66K	44.16K
Feb 24, 2020	THROSBY MARK	SALE	17.74	57.09K	1.01M	43.82K
Feb 18, 2020	DE KRUIF JOHN	SALE	18.98	1.27K	24.07K	11.65K
Jan 16, 2020	BVF PARTNERS L P/IL	PURCHASE	16.15	19.73K	318.59K	244.3K
Jan 13, 2020	BVF PARTNERS L P/IL	PURCHASE	14.98	5.41K	80.97K	224.58K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE77.09M9

SALES10K2

NET SHARES77.08M7

SHARES HELD577.44M11

% NET SHARES-86.65%-36.36%

MRUS Stock Ownership Breakdown

Merus NV

Stock Outstanding Shares

Market Insider

Institutional Ownership

Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions

Stock Outstanding Shares

Market Insider

Institutional Ownership

Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions