How many institutions own MLTX stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own MLTX shares is 180, representing 75.64% of the company's common stock.

Who are the major shareholders selling MoonLake Immunotherapeutics stock?

BVF INC/IL, in the last quarter, reduced its stake in MLTX by -18.99% restricting it's holding to 16 million shares of worth nearly $298.26M. D. E. SHAW & CO., INC. also lessened -3.63% of the MLTX shares from its portfolio, reducing its holding to 2.39 million shares of worth $44.56M. DIMENSIONAL FUND ADVISORS LP also shunned MLTX shares holding by -85.67% last quarter which brought its holding to 26.31 thousand shares worth $490.36K.

Investors who are buying MLTX stock?

As per its latest 13F filing, INVESCO LTD. increased its stake in MLTX by 100% in the last quarter. The institutional holder raised its holding to 139.57 thousand shares having worth more than $2.60M. TD ASSET MANAGEMENT INC also added 12.59% more shares of MLTX to its portfolio, raising its holding to 142.71 thousand shares of worth $2.66M. CANDRIAM S.C.A. also increased its MLTX shares holding by 509.05% which brought its holding to 818.13 thousand shares worth $15.25M.

MLTX's major insiders: who are they?

The insider with the most stakes in MLTX is Santos da Silva Jorge , Chief Executive Officer at the company. Additionally, MLTX stock is highly held by Chief Scientific Officer Reich Kristian and Former 10% Owner Chen Bihua among others.

Did an insider recently sell MLTX stock?

Company executives, directors, and other insiders own 10.41% percent of MoonLake Immunotherapeutics's stock. Within the last six months, there have been 12 transaction(s) in which MLTX insiders have sold stock, totaling 670.28K shares. Insiders that have sold shares include BODENSTEDT MATTHIAS, REICH KRISTIAN, and SANTOS DA SILVA JORGE.

Which insider recently purchased MLTX stock?

There have been 0 transaction(s) during the past 6-months in which MoonLake Immunotherapeutics insiders have bought stock, totalling 0 shares

How much of MLTX does insiders own?

Around 22.61M MoonLake Immunotherapeutics shares are held by insiders, which represents about 10.41% of MLTX stock.

Who is the insider with the largest stake?

MLTX Chief Executive Officer, Santos da Silva Jorge holds the largest portfolio of the company's shares. MLTX shares owned by Santos total nearly 2.92 million.

Which institution holds the most shares in MLTX?

INVESCO LTD. is the largest institutional owner in MLTX which holds 139.57 thousand shares worth $2.60M or 0.22% of the total MLTX shares outstanding followed by TD ASSET MANAGEMENT INC with ownership of 142.71 thousand shares representing 0.22% of the MLTX ownership. CANDRIAM S.C.A. is the third largest stakeholder with 818.13 thousand shares or 1.27% of the ownership worth more than $15.25M.

Is MoonLake Immunotherapeutics stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the MLTX is concerned, it is a stock which is optionable.

Is there a short position on MLTX's shares?

Number of MLTX shares short is 6.13M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding MLTX shares are there?

As of today, 63.50M shares of MLTX are outstanding.

Is there many float in MLTX stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, MLTX has 24.16M shares in float.

MLTX short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for MLTX is 12.16.

MoonLake Immunotherapeutics (MLTX) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares9.66

Short Percent Of Float21.68

Shares Outstanding63.50M

Shares Float24.16M

Shares Short6.13M

Short Ratio12.16

21.68%

Short % of Float

9.66%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

10.41% Percentage of Shares held by All Insiders

75.64% Percentage of Shares held by All Institutions

84.42% Percentage of Float held by Institutions

180

Number of Institutions Holding Shares

Institutional Ownership

About 75.64% of MLTX shares are held by financial institutions. INVESCO LTD. is the top corporate investor, holding 139.57K shares valued at $2.60M. A 0.22% stake in MoonLake Immunotherapeutics is owned by the company. TD ASSET MANAGEMENT INC owns 142.71K shares valued at $2.66M, which translates its holding of 0.22% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Mar 31, 2026	INVESCO LTD.	0.22%	139.57K	2.6M	139.57K	+100.00%
Mar 31, 2026	TD ASSET MANAGEMENT INC	0.22%	142.71K	2.66M	15.96K	+12.59%
Mar 31, 2026	CANDRIAM S.C.A.	1.27%	818.13K	15.25M	683.8K	+509.05%
Mar 31, 2026	BLACKROCK, INC.	1.59%	1.02M	19.05M	735.26K	+256.55%
Mar 31, 2026	JPMORGAN CHASE & CO	1.69%	1.09M	18.43M	250.78K	+29.93%
Mar 31, 2026	BVF INC/IL	24.82%	16M	298.26M	-3.75M	-18.99%
Mar 31, 2026	DEEP TRACK CAPITAL, LP	9.94%	6.41M	119.46M	1.8M	+39.02%
Mar 31, 2026	CORMORANT ASSET MANAGEMENT, LP	6.95%	4.48M	83.52M	125K	+2.87%
Mar 31, 2026	JANUS HENDERSON GROUP PLC	5.35%	3.45M	64.3M	1.36M	+64.68%
Mar 31, 2026	D. E. SHAW & CO., INC.	3.71%	2.39M	44.56M	-90.11K	-3.63%
Mar 31, 2026	DIMENSIONAL FUND ADVISORS LP	0.04%	26.31K	490.36K	-157.25K	-85.67%
Mar 31, 2026	NUVEEN, LLC	0.05%	33.42K	622.89K	-604.02K	-94.76%
Mar 31, 2026	LEGAL & GENERAL GROUP PLC	0.03%	20.56K	383.22K	4.48K	+27.87%
Mar 31, 2026	NORTHERN TRUST CORP	0.03%	19.48K	363.05K	998	+5.40%
Mar 31, 2026	AXQ CAPITAL, LP	0.03%	19.24K	358.65K	19.24K	+100.00%
Mar 31, 2026	VANGUARD ASSET MANAGEMENT, LTD	0.04%	23.83K	444.15K	23.83K	+100.00%
Mar 31, 2026	OPTIMIZE FINANCIAL INC	0.04%	24.42K	455.17K	24.42K	+100.00%
Mar 31, 2026	VIRTUS INVESTMENT ADVISERS, INC.	0.03%	18.44K	343.65K	449	+2.50%
Mar 31, 2026	ACADIAN ASSET MANAGEMENT LLC	0.03%	16.53K	305K	16.53K	+100.00%
Mar 31, 2026	FOX RUN MANAGEMENT, L.L.C.	0.03%	16.52K	279.65K	-55.44K	-77.05%
Mar 31, 2026	WINTON GROUP LTD	0.02%	15.67K	292.09K	15.67K	+100.00%
Mar 31, 2026	CITIGROUP INC	0.02%	13.69K	255.2K	12.78K	+1,404.51%
Mar 31, 2026	WELLS FARGO & COMPANY/MN	0.02%	12.52K	233.37K	2.52K	+25.20%
Mar 31, 2026	ENTROPY TECHNOLOGIES, LP	0.02%	11.85K	220.96K	-18.45K	-60.88%
Mar 31, 2026	IMC-CHICAGO, LLC	0.02%	11.35K	211.6K	-25.12K	-68.87%
Mar 31, 2026	CAPITAL FUND MANAGEMENT S.A.	0.02%	11.26K	209.89K	11.26K	+100.00%
Mar 31, 2026	STATE OF NEW JERSEY COMMON PENSION FUND D	0.02%	10.86K	202.51K	10.86K	+100.00%
Mar 31, 2026	VIRTU FINANCIAL LLC	0.02%	10.53K	196K	-2.06K	-16.34%
Mar 31, 2026	SG AMERICAS SECURITIES, LLC	0.01%	9.35K	174K	-12.54K	-57.28%
Mar 31, 2026	BIOIMPACT CAPITAL LLC	2.81%	1.81M	33.76M	1.81M	+100.00%
Mar 31, 2026	WEISS ASSET MANAGEMENT LP	2.65%	1.71M	31.84M	1.38M	+413.07%
Mar 31, 2026	PRICE T ROWE ASSOCIATES INC /MD/	2.01%	1.29M	24.14M	335.31K	+34.94%
Mar 31, 2026	GOLDMAN SACHS GROUP INC	1.75%	1.13M	21.07M	859.57K	+317.58%
Mar 31, 2026	ALGERT GLOBAL LLC	0.23%	151.26K	2.82M	-70.36K	-31.75%
Mar 31, 2026	RICE HALL JAMES & ASSOCIATES, LLC	0.26%	167.77K	3.13M	40.3K	+31.62%
Mar 31, 2026	BOXER CAPITAL MANAGEMENT, LLC	0.43%	275K	5.13M	0	0
Mar 31, 2026	MORGAN STANLEY	0.95%	614.48K	11.45M	-430.1K	-41.17%
Mar 31, 2026	GROUP ONE TRADING, L.P.	0.03%	21.56K	401.93K	-8.91K	-29.25%
Mar 31, 2026	CONGRESS ASSET MANAGEMENT CO /MA	0.28%	178.56K	3.33M	107.46K	+151.15%
Mar 31, 2026	ACUTA CAPITAL PARTNERS, LLC	0.3%	191.76K	3.57M	132.48K	+223.48%
Mar 31, 2026	MILLENNIUM MANAGEMENT LLC	0.89%	576.09K	10.74M	-226.63K	-28.23%
Mar 31, 2026	JEFFERIES FINANCIAL GROUP INC.	0.78%	500K	9.32M	0	0
Mar 31, 2026	BALYASNY ASSET MANAGEMENT L.P.	1.65%	1.07M	19.86M	-505.46K	-32.17%
Mar 31, 2026	VIVO CAPITAL, LLC	1.55%	1M	18.64M	0	0
Mar 31, 2026	BANK OF AMERICA CORP /DE/	1.12%	724.79K	13.51M	711.26K	+5,255.75%
Mar 31, 2026	CITADEL ADVISORS LLC	1.03%	664K	12.38M	-828.8K	-55.52%
Mar 31, 2026	GREAT POINT PARTNERS LLC	0.78%	500K	9.32M	500K	+100.00%
Mar 31, 2026	MARINER, LLC	0.07%	44.95K	837.84K	24.79K	+122.98%
Mar 31, 2026	AVIDITY PARTNERS MANAGEMENT LP	0.08%	50K	819K	50K	+100.00%
Mar 31, 2026	ALPS ADVISORS INC	0.09%	58.4K	1.09M	226	+0.39%
Mar 31, 2026	SWISS NATIONAL BANK	0.1%	61.5K	1.15M	0	0
Mar 31, 2026	ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	0.11%	70.14K	1.31M	70.14K	+100.00%
Mar 31, 2026	POINT72 ASSET MANAGEMENT, L.P.	2.12%	1.37M	25.51M	596.02K	+77.15%
Mar 31, 2026	LOGOS GLOBAL MANAGEMENT LP	2.33%	1.5M	27.96M	-250K	-14.29%
Mar 31, 2026		0.27%	174.25K	3.25M	174.25K	+100.00%
Mar 31, 2026	RHENMAN & PARTNERS ASSET MANAGEMENT AB	0.37%	239.5K	4.46M	-124.5K	-34.20%
Mar 31, 2026	BNP PARIBAS ARBITRAGE, SNC	0.37%	239.84K	4.47M	228.53K	+2,020.58%
Mar 31, 2026	SUSQUEHANNA PORTFOLIO STRATEGIES, LLC	0.39%	253.97K	4.73M	0	0
Mar 31, 2026	HIGHVISTA STRATEGIES LLC	0.3%	193.96K	3.62M	193.96K	+100.00%
Mar 31, 2026	EXOME ASSET MANAGEMENT LLC	0.33%	215.38K	4.01M	215.38K	+100.00%
Mar 31, 2026	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.41%	265.6K	4.95M	69.9K	+35.72%
Mar 31, 2026	JUMP FINANCIAL, LLC	0.51%	325.97K	6.08M	-99.59K	-23.40%
Mar 31, 2026	TREXQUANT INVESTMENT LP	0.77%	495.34K	9.23M	311.02K	+168.74%
Mar 31, 2026	HRT FINANCIAL LP	0.76%	487.58K	9.09M	-148.32K	-23.32%
Mar 31, 2026	ADAR1 CAPITAL MANAGEMENT, LLC	0.71%	457.14K	8.52M	457.14K	+100.00%
Mar 31, 2026	GRANAHAN INVESTMENT MANAGEMENT, LLC	0.34%	220.6K	4.11M	22.29K	+11.24%
Mar 31, 2026	HOLOCENE ADVISORS, LP	0.93%	600K	11.18M	600K	+100.00%
Mar 31, 2026	TWO SIGMA INVESTMENTS, LP	1.74%	1.12M	20.92M	337.5K	+43.00%
Mar 31, 2026	JANE STREET GROUP, LLC	0.7%	453.63K	8.46M	-1.23M	-73.03%
Mar 31, 2026	CASDIN CAPITAL, LLC	0.7%	450K	8.39M	450K	+100.00%
Mar 31, 2026	LONGAEVA PARTNERS L.P.	0.64%	410K	7.64M	410K	+100.00%
Mar 31, 2026	RENAISSANCE TECHNOLOGIES LLC	0.43%	276.77K	5.16M	142.3K	+105.82%
Mar 31, 2026	VOLEON CAPITAL MANAGEMENT LP	0.58%	373.02K	6.95M	-126.08K	-25.26%
Mar 31, 2026	FIRST TURN MANAGEMENT, LLC	0.49%	315.56K	5.88M	52.92K	+20.15%
Mar 31, 2026	WALLEYE CAPITAL LLC	0.5%	320.47K	5.97M	244.72K	+323.05%
Mar 31, 2026	UBS ASSET MANAGEMENT AMERICAS INC	0.12%	74.16K	1.38M	74.16K	+100.00%
Mar 31, 2026	GSA CAPITAL PARTNERS LLP	0.12%	80.23K	1.5M	-9K	-10.09%
Mar 31, 2026	HEADLANDS TECHNOLOGIES LLC	0.15%	97.13K	1.81M	97.13K	+100.00%
Mar 31, 2026	CENTIVA CAPITAL, LP	0.18%	115.9K	2.16M	10.2K	+9.65%
Mar 31, 2026	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.19%	120.31K	2.24M	-92.69K	-43.52%
Mar 31, 2026	Y-INTERCEPT (HONG KONG) LTD	0.2%	127.09K	2.37M	31.12K	+32.42%
Dec 31, 2025	BVF INC/IL	31.17%	19.75M	260.32M	0	0
Dec 31, 2025	BOXER CAPITAL MANAGEMENT, LLC	0.43%	275K	3.62M	25K	+10.00%
Dec 31, 2025	WALLEYE CAPITAL LLC	0.09%	54.6K	719.63K	43K	+370.69%
Dec 31, 2025	JUMP FINANCIAL, LLC	0.67%	425.56K	5.61M	425.56K	+100.00%
Dec 31, 2025	EAGLE HEALTH INVESTMENTS LP	0.3%	187.6K	2.47M	187.6K	+100.00%
Dec 31, 2025	TWO SIGMA ADVISERS, LP	0.21%	131.7K	1.74M	92.38K	+234.91%
Dec 31, 2025	TD ASSET MANAGEMENT INC	0.2%	126.74K	1.67M	20.13K	+18.89%
Dec 31, 2025	SQUAREPOINT OPS LLC	0.19%	121.64K	1.6M	90.95K	+296.35%
Dec 31, 2025	CENTIVA CAPITAL, LP	0.17%	105.7K	1.39M	-27.2K	-20.47%
Dec 31, 2025	TUDOR INVESTMENT CORP ET AL	0.16%	103.52K	1.36M	103.52K	+100.00%
Dec 31, 2025	Y-INTERCEPT (HONG KONG) LTD	0.15%	95.97K	1.26M	95.97K	+100.00%
Dec 31, 2025	GSA CAPITAL PARTNERS LLP	0.14%	89.24K	1.18M	89.24K	+100.00%
Dec 31, 2025	WALLEYE TRADING LLC	0.14%	87.39K	1.15M	33.69K	+62.74%
Dec 31, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.14%	85.57K	1.13M	20.31K	+31.13%
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.11%	72.61K	956.44M	10.22K	+16.38%
Dec 31, 2025	FOX RUN MANAGEMENT, L.L.C.	0.11%	71.96K	948.46K	60.56K	+531.25%
Dec 31, 2025	CONGRESS ASSET MANAGEMENT CO /MA	0.11%	71.1K	937.05K	-2.27K	-3.09%
Dec 31, 2025	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	0.1%	61.95K	817K	61.68K	+22,675.00%
Dec 31, 2025	SWISS NATIONAL BANK	0.1%	61.5K	810.57K	18.5K	+43.02%
Dec 31, 2025	ALPS ADVISORS INC	0.09%	58.17K	766.67K	27.41K	+89.13%
Dec 31, 2025	STATE STREET CORP	0.08%	50.97K	671.82K	-1.91K	-3.62%
Dec 31, 2025	BARCLAYS PLC	0.08%	50.25K	662.31K	50.24K	+313,968.75%
Dec 31, 2025	LOGOS GLOBAL MANAGEMENT LP	2.76%	1.75M	23.07M	1.75M	+100.00%
Dec 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.31%	195.7K	2.58M	87.6K	+81.04%
Dec 31, 2025	FMR LLC	0.25%	156.28K	2.06M	-570.66K	-78.50%
Dec 31, 2025		0.28%	175.73K	2.32M	175.73K	+100.00%
Dec 31, 2025	DIMENSIONAL FUND ADVISORS LP	0.29%	183.55K	2.42M	172.55K	+1,568.35%
Dec 31, 2025	TREXQUANT INVESTMENT LP	0.29%	184.32K	2.43M	184.32K	+100.00%
Dec 31, 2025	UBS GROUP AG	0.38%	239.02K	3.15M	154.67K	+183.38%
Dec 31, 2025	SCHONFELD STRATEGIC ADVISORS LLC	0.51%	322.26K	4.25M	-643.14K	-66.62%
Dec 31, 2025	JANE STREET GROUP, LLC	2.65%	1.68M	22.17M	1.66M	+7,553.78%
Dec 31, 2025	SG AMERICAS SECURITIES, LLC	0.03%	21.89K	288K	4.36K	+24.89%
Dec 31, 2025	AXIOM INVESTORS LLC /DE	0.04%	26K	342.65K	818	+3.25%
Dec 31, 2025	SIMPLEX TRADING, LLC	0.05%	28.97K	381.85K	-29.26K	-50.24%
Dec 31, 2025	ENTROPY TECHNOLOGIES, LP	0.05%	30.3K	399.35K	30.3K	+100.00%
Dec 31, 2025	GROUP ONE TRADING, L.P.	0.05%	30.48K	401.67K	15.01K	+97.01%
Dec 31, 2025	IMC-CHICAGO, LLC	0.06%	36.47K	480.65K	36.47K	+100.00%
Dec 31, 2025	J. GOLDMAN & CO LP	0.52%	328.4K	4.33M	291.2K	+782.80%
Dec 31, 2025	WEISS ASSET MANAGEMENT LP	0.53%	332.96K	4.39M	332.96K	+100.00%
Dec 31, 2025	STEMPOINT CAPITAL LP	0.55%	348.4K	4.59M	348.4K	+100.00%
Dec 31, 2025	CITADEL ADVISORS LLC	0.6%	380.89K	5.02M	331.56K	+672.06%
Dec 31, 2025	TWO SIGMA INVESTMENTS, LP	1.24%	784.81K	10.34M	330.54K	+72.76%
Dec 31, 2025	GRANAHAN INVESTMENT MANAGEMENT, LLC	0.31%	198.31K	2.61M	198.31K	+100.00%
Dec 31, 2025	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.34%	213K	2.81M	213K	+100.00%
Dec 31, 2025	ALGERT GLOBAL LLC	0.35%	221.62K	2.92M	221.62K	+100.00%
Dec 31, 2025	SUSQUEHANNA PORTFOLIO STRATEGIES, LLC	0.4%	253.97K	3.35M	253.97K	+100.00%
Dec 31, 2025	683 CAPITAL MANAGEMENT, LLC	0.4%	255.4K	3.37M	255.4K	+100.00%
Dec 31, 2025	VOLEON CAPITAL MANAGEMENT LP	0.79%	499.1K	6.58M	458.83K	+1,139.29%
Dec 31, 2025	POINT72 ASSET MANAGEMENT, L.P.	1.22%	772.5K	10.18M	762.7K	+7,782.65%
Dec 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.51%	959.55K	12.65M	136.6K	+16.60%
Dec 31, 2025	BALYASNY ASSET MANAGEMENT L.P.	2.48%	1.57M	20.71M	-128.16K	-7.54%
Dec 31, 2025	JANUS HENDERSON GROUP PLC	3.31%	2.1M	27.66M	2.08M	+18,782.77%
Dec 31, 2025	D. E. SHAW & CO., INC.	3.91%	2.48M	32.7M	2.48M	+100.00%
Dec 31, 2025	CORMORANT ASSET MANAGEMENT, LP	6.87%	4.36M	57.4M	2.36M	+118.41%
Dec 31, 2025	FIRST TURN MANAGEMENT, LLC	0.41%	262.64K	3.46M	0	0
Dec 31, 2025	CAMPBELL & CO INVESTMENT ADVISER LLC	0.02%	13.45K	177.25K	13.45K	+100.00%
Dec 31, 2025	ZURCHER KANTONALBANK (ZURICH CANTONALBANK)	0.02%	13.59K	179.14K	7.67K	+129.63%
Dec 31, 2025	SKOPOS LABS, INC.	0.02%	14.92K	204.33K	14.92K	+100.00%
Dec 31, 2025	LEGAL & GENERAL GROUP PLC	0.03%	16.08K	211.91K	-4.83K	-23.09%
Dec 31, 2025	MARINER, LLC	0.03%	20.16K	265.69K	20.16K	+100.00%
Dec 31, 2025	VANGUARD GROUP INC	0.42%	266.15K	3.51M	145.91K	+121.34%
Dec 31, 2025	GOLDMAN SACHS GROUP INC	0.43%	270.67K	3.57M	-92.21K	-25.41%
Dec 31, 2025	BLACKROCK, INC.	0.45%	286.59K	3.78M	161.21K	+128.58%
Dec 31, 2025	RHENMAN & PARTNERS ASSET MANAGEMENT AB	0.57%	364K	4.8M	157K	+75.85%
Dec 31, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	0.63%	400K	5.27M	400K	+100.00%
Dec 31, 2025	JEFFERIES FINANCIAL GROUP INC.	0.79%	500K	6.59M	475K	+1,900.00%
Dec 31, 2025	HRT FINANCIAL LP	1%	635.9K	8.38M	492.63K	+343.83%
Dec 31, 2025	NUVEEN, LLC	1.01%	637.43K	8.4M	1.74K	+0.27%
Dec 31, 2025	JPMORGAN CHASE & CO	1.32%	837.74K	11.04M	663.58K	+381.01%
Dec 31, 2025	VIVO CAPITAL, LLC	1.58%	1M	13.18M	1M	+100.00%
Dec 31, 2025	MORGAN STANLEY	1.65%	1.04M	13.77M	787.93K	+307.00%
Dec 31, 2025	DEEP TRACK CAPITAL, LP	7.27%	4.61M	60.76M	4.61M	+100.00%
Dec 31, 2025	MILLENNIUM MANAGEMENT LLC	1.27%	802.72K	10.58M	713.55K	+800.20%
Dec 31, 2025	CANDRIAM S.C.A.	0.21%	134.33K	1.77M	687	+0.51%
Dec 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0.21%	134.47K	1.77M	134.47K	+100.00%
Sep 30, 2025	MORGAN STANLEY	0.41%	256.66K	1.84M	213.42K	+493.57%
Sep 30, 2025	JANE STREET GROUP, LLC	1.28%	812.7K	5.83M	737.6K	+982.16%
Sep 30, 2025	GROUP ONE TRADING, L.P.	0.02%	15.47K	110.91M	15.47K	+100.00%
Sep 30, 2025	NUVEEN, LLC	1%	635.7K	4.56M	-155.86K	-19.69%
Sep 30, 2025	TD ASSET MANAGEMENT INC	0.17%	106.61K	764.39K	-79.54K	-42.73%
Sep 30, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	0.24%	151.5K	1.09M	117.18K	+341.50%
Sep 30, 2025	JPMORGAN CHASE & CO	0.28%	174.16K	1.25M	134.76K	+342.07%
Sep 30, 2025	EXOME ASSET MANAGEMENT LLC	0.28%	178.08K	1.28M	178.08K	+100.00%
Sep 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.17%	108.1K	775.08K	25.7K	+31.19%
Sep 30, 2025	SCHRODER INVESTMENT MANAGEMENT GROUP	0.31%	195.49K	1.22M	176.1K	+908.20%
Sep 30, 2025	CITADEL ADVISORS LLC	0.31%	195.6K	1.4M	176.7K	+934.92%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	0.57%	362.87K	2.6M	-912.7K	-71.55%
Sep 30, 2025	IKARIAN CAPITAL, LLC	0.69%	435.84K	3.12M	435.84K	+100.00%
Sep 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.3%	822.96K	5.9M	-1.79M	-68.51%
Sep 30, 2025	SCHONFELD STRATEGIC ADVISORS LLC	1.53%	965.41K	6.92M	965.41K	+100.00%
Sep 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	2.37%	1.5M	10.76M	1.5M	+100.00%
Sep 30, 2025	BALYASNY ASSET MANAGEMENT L.P.	2.69%	1.7M	12.18M	1.28M	+301.55%
Sep 30, 2025	CORMORANT ASSET MANAGEMENT, LP	3.15%	1.99M	14.3M	-6.5M	-76.52%
Sep 30, 2025	AVORO CAPITAL ADVISORS LLC	3.16%	2M	14.34M	-2.15M	-51.81%
Sep 30, 2025	ASSETMARK, INC	0%	888	6.37K	888	+100.00%
Sep 30, 2025	SBI SECURITIES CO., LTD.	0%	952	6.83K	952	+100.00%
Sep 30, 2025	US BANCORP \DE\	0%	1.31K	9.41K	-1.44K	-52.24%
Sep 30, 2025	DEUTSCHE BANK AG\	0%	2.34K	16.78K	785	+50.48%
Sep 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0%	2.36K	16.9K	-3.1K	-56.83%
Sep 30, 2025	ADVISORS ASSET MANAGEMENT, INC.	0.01%	3.99K	28.64K	-15	-0.37%
Sep 30, 2025	KLP KAPITALFORVALTNING AS	0.01%	4.5K	32.27K	0	0
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0.01%	5.21K	37.34K	4.48K	+618.34%
Sep 30, 2025	ENSIGN PEAK ADVISORS, INC	0.01%	5.54K	39.72K	-3.6K	-39.39%
Sep 30, 2025	COVESTOR LTD	0.01%	6.44K	46K	6.44K	+100.00%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.01%	7.3K	52.31K	1.16K	+18.87%
Sep 30, 2025	BARCLAYS PLC	0.01%	8K	57.36K	-2K	-20.00%
Sep 30, 2025	CITIGROUP INC	0.01%	8.02K	57.51K	5.05K	+169.98%
Sep 30, 2025	HANDELSBANKEN FONDER AB	0.02%	10.6K	76K	0	0
Sep 30, 2025	DIMENSIONAL FUND ADVISORS LP	0.02%	11K	78.89K	-41.72K	-79.13%
Sep 30, 2025	FOX RUN MANAGEMENT, L.L.C.	0.02%	11.4K	81.74K	11.4K	+100.00%
Sep 30, 2025	HARBOR CAPITAL ADVISORS, INC.	0.02%	13.71K	98K	-37.7K	-73.34%
Sep 30, 2025	ERSTE ASSET MANAGEMENT GMBH	0.02%	15K	93.68K	0	0
Sep 30, 2025	MYDA ADVISORS LLC	0.02%	15K	107.55K	15K	+100.00%
Sep 30, 2025	VANGUARD GROUP INC	0.19%	120.24K	862.14K	-626	-0.52%
Sep 30, 2025	CANDRIAM S.C.A.	0.21%	133.64K	958.21K	-11.19K	-7.72%
Sep 30, 2025	CATALIO CAPITAL MANAGEMENT, LP	0.21%	133.13K	954.55K	-29.47K	-18.12%
Sep 30, 2025	BLACKROCK, INC.	0.2%	125.38K	898.98K	-201.96K	-61.70%
Sep 30, 2025	SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC	0.16%	100K	717K	100K	+100.00%
Sep 30, 2025	WALLEYE TRADING LLC	0.23%	146.1K	1.05M	146.1K	+100.00%
Sep 30, 2025	TORONTO DOMINION BANK	0.5%	316K	2.27M	316K	+100.00%
Sep 30, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.1%	65.26K	467.89K	-44.71K	-40.66%
Sep 30, 2025	LION POINT CAPITAL, LP	0.11%	67.5K	483.98K	67.5K	+100.00%
Sep 30, 2025	SG AMERICAS SECURITIES, LLC	0.03%	17.53K	126K	17.53K	+100.00%
Sep 30, 2025	VICTORY CAPITAL MANAGEMENT INC	0.03%	18.79K	134.72K	-119.58K	-86.42%
Sep 30, 2025	LEGAL & GENERAL GROUP PLC	0.03%	20.91K	149.89K	0	0
Sep 30, 2025	HUDSON BAY CAPITAL MANAGEMENT LP	0.03%	20K	143.4K	-85K	-80.95%
Sep 30, 2025	JEFFERIES FINANCIAL GROUP INC.	0.04%	25K	179.25K	19.81K	+381.79%
Sep 30, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.05%	30K	215.1K	-52.02K	-63.42%
Sep 30, 2025	ALPS ADVISORS INC	0.05%	30.76K	220.52K	-3.53K	-10.31%
Sep 30, 2025	FRANKLIN RESOURCES INC	0.05%	33.58K	240.75K	33.58K	+100.00%
Sep 30, 2025	HAP TRADING, LLC	0.03%	20K	104K	20K	+100.00%
Sep 30, 2025	SWISS NATIONAL BANK	0.07%	43K	308.31K	700	+1.65%
Sep 30, 2025	SIMPLEX TRADING, LLC	0.09%	58.23K	417K	58.23K	+100.00%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.1%	62.39K	447.01K	2.83K	+4.76%
Sep 30, 2025	FMR LLC	1.15%	726.93K	5.21M	-5M	-87.31%
Sep 30, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.39%	244K	1.75M	215.5K	+756.14%
Sep 30, 2025	RHENMAN & PARTNERS ASSET MANAGEMENT AB	0.33%	207K	1.48M	162K	+360.00%
Sep 30, 2025	FIRST TURN MANAGEMENT, LLC	0.42%	262.64K	1.88M	262.64K	+100.00%
Sep 30, 2025	VERITION FUND MANAGEMENT LLC	0.43%	272.77K	1.96M	249.24K	+1,059.38%
Sep 30, 2025	D. E. SHAW & CO., INC.	0.15%	92.3K	661.79K	92.3K	+100.00%
Sep 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.21%	131.99K	946.38K	-15.73K	-10.65%
Sep 30, 2025	CENTIVA CAPITAL, LP	0.21%	132.9K	952.89K	132.9K	+100.00%
Sep 30, 2025	RICE HALL JAMES & ASSOCIATES, LLC	0.21%	134.84K	966.77K	-7.49K	-5.26%
Sep 30, 2025	CLEARBRIDGE INVESTMENTS, LLC	0.21%	135.5K	971.51K	107.07K	+376.65%
Sep 30, 2025	MARSHALL WACE, LLP	0.51%	321.11K	2.3M	-208.1K	-39.32%
Sep 30, 2025	TWO SIGMA INVESTMENTS, LP	0.72%	454.27K	3.26M	454.27K	+100.00%
Sep 30, 2025	BVF INC/IL	31.21%	19.75M	141.62M	0	0
Sep 30, 2025	ALLY BRIDGE GROUP (NY) LLC	0.11%	69K	494.73K	69K	+100.00%
Sep 30, 2025	PRINCIPAL FINANCIAL GROUP INC	0.11%	70.94K	508.66K	70.94K	+100.00%
Sep 30, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.11%	71.01K	509.14K	71.01K	+100.00%
Sep 30, 2025	CONGRESS ASSET MANAGEMENT CO /MA	0.12%	73.37K	526.03K	514	+0.71%
Sep 30, 2025	UBS GROUP AG	0.13%	84.35K	604.77K	4K	+4.97%
Sep 30, 2025	HRT FINANCIAL LP	0.23%	143.28K	1.03M	143.28K	+100.00%
Sep 30, 2025	LMR PARTNERS LLP	0.23%	145.2K	1.04M	145.2K	+100.00%
Sep 30, 2025	CAPTION MANAGEMENT, LLC	0.39%	249.8K	1.79M	21.1K	+9.23%
Sep 30, 2025	BOXER CAPITAL MANAGEMENT, LLC	0.4%	250K	1.79M	250K	+100.00%
Jun 30, 2025	OCTAGON CAPITAL ADVISORS LP	0.23%	148K	6.99M	-148K	-50.00%
Jun 30, 2025	VESTAL POINT CAPITAL, LP	0.87%	550K	25.96M	350K	+175.00%
Jun 30, 2025	BALYASNY ASSET MANAGEMENT L.P.	0.67%	423.17K	19.97M	344.34K	+436.78%
Jun 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.29%	186.57K	8.81M	186.57K	+100.00%
Jun 30, 2025	CONGRESS ASSET MANAGEMENT CO /MA	0.12%	72.85K	3.44M	121	+0.17%
Jun 30, 2025	MOODY ALDRICH PARTNERS LLC	0.09%	54.42K	2.57M	-829	-1.50%
Jun 30, 2025	RHENMAN & PARTNERS ASSET MANAGEMENT AB	0.07%	45K	2.12M	0	0
Jun 30, 2025	MORGAN STANLEY	0.07%	43.24K	2.04B	-11.09K	-20.42%
Jun 30, 2025	AVIDITY PARTNERS MANAGEMENT LP	0.06%	39K	1.84M	39K	+100.00%
Jun 30, 2025	TUDOR INVESTMENT CORP ET AL	0.05%	31.71K	1.5M	122	+0.39%
Jun 30, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.13%	82.02K	3.87M	82.02K	+100.00%
Jun 30, 2025	FMR LLC	9.06%	5.73M	270.48M	-596.47K	-9.43%
Jun 30, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.11%	70.9K	3.35M	42.4K	+148.77%
Jun 30, 2025	BVF INC/IL	31.21%	19.75M	932.26M	0	0
Jun 30, 2025	FEDERATED HERMES, INC.	1.97%	1.25M	58.93M	-20.78K	-1.64%
Jun 30, 2025	RTW INVESTMENTS, LP	1.17%	741.09K	34.98M	741.09K	+100.00%
Jun 30, 2025	WOODLINE PARTNERS LP	0.49%	310.6K	14.66M	14.45K	+4.88%
Jun 30, 2025	POLAR CAPITAL HOLDINGS PLC	0.39%	247.5K	11.68M	-852.5K	-77.50%
Jun 30, 2025	AMERIPRISE FINANCIAL INC	0.32%	200.32K	9.46M	-1.2K	-0.60%
Jun 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.23%	147.72K	6.97M	-174.39K	-54.14%
Jun 30, 2025	VICTORY CAPITAL MANAGEMENT INC	0.22%	138.37K	6.53M	-119.78K	-46.40%
Jun 30, 2025	VANGUARD GROUP INC	0.19%	120.87K	5.71M	6.85K	+6.01%
Jun 30, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.17%	109.97K	5.19M	-14.94K	-11.96%
Jun 30, 2025	HUDSON BAY CAPITAL MANAGEMENT LP	0.17%	105K	4.96M	25K	+31.25%
Jun 30, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.2%	125K	5.9M	125K	+100.00%
Jun 30, 2025	CORMORANT ASSET MANAGEMENT, LP	13.42%	8.49M	400.92M	0	0
Jun 30, 2025	ALLIANCEBERNSTEIN L.P.	1.8%	1.14M	53.71M	171.93K	+17.80%
Jun 30, 2025	PARADIGM BIOCAPITAL ADVISORS LP	1.39%	878.32K	41.46M	250.9K	+39.99%
Jun 30, 2025	HOOD RIVER CAPITAL MANAGEMENT LLC	1.07%	675.45K	31.88M	12.46K	+1.88%
Jun 30, 2025	BLACKROCK, INC.	0.52%	327.34K	15.45M	41.13K	+14.37%
Jun 30, 2025	BIOIMPACT CAPITAL LLC	0.5%	313.57K	14.8M	-2.48K	-0.78%
Jun 30, 2025		0.26%	162.6K	7.67M	47.98K	+41.86%
Jun 30, 2025	JENNISON ASSOCIATES LLC	0.1%	62.32K	2.94M	62.32K	+100.00%
Jun 30, 2025	HARBOR CAPITAL ADVISORS, INC.	0.08%	51.41K	2.43M	-50.61K	-49.61%
Jun 30, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	0.05%	34.31K	1.62M	28.89K	+532.63%
Jun 30, 2025	ALPS ADVISORS INC	0.05%	34.29K	1.62M	-12.81K	-27.20%
Jun 30, 2025	AVORO CAPITAL ADVISORS LLC	6.56%	4.15M	195.88M	1.38M	+49.81%
Jun 30, 2025	WESTFIELD CAPITAL MANAGEMENT CO LP	1.99%	1.26M	59.44M	-175.39K	-12.22%
Jun 30, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.39%	246.11K	11.62M	-146.81K	-37.36%
Jun 30, 2025	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.32%	200K	9.44M	0	0
Jun 30, 2025	MARSHALL WACE, LLP	0.84%	529.21K	24.98M	-111.71K	-17.43%
Jun 30, 2025	SIREN, L.L.C.	0.8%	508.27K	23.99M	508.27K	+100.00%
Jun 30, 2025	CAPTION MANAGEMENT, LLC	0.36%	228.7K	10.79M	198.7K	+662.33%
Jun 30, 2025	FRED ALGER MANAGEMENT, LLC	0.47%	295.62K	13.95M	-347.26K	-54.02%
Jun 30, 2025	SATURN V CAPITAL MANAGEMENT LLC	0.46%	290.78K	13.73M	-53.07K	-15.43%
Jun 30, 2025	5AM VENTURE MANAGEMENT, LLC	0.45%	282.31K	13.33M	0	0
Jun 30, 2025	LOGOS GLOBAL MANAGEMENT LP	0.32%	200K	9.44M	-150K	-42.86%
Jun 30, 2025	TD ASSET MANAGEMENT INC	0.29%	186.15K	8.79M	-30.75K	-14.18%
Jun 30, 2025	IKARIAN CAPITAL, LLC	0.15%	94.5K	4.46M	0	0
Jun 30, 2025	AXA S.A.	0.13%	83.84K	3.96M	-20.21K	-19.42%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.13%	82.4K	3.89M	75.6K	+1,111.76%
Jun 30, 2025	GRANAHAN INVESTMENT MANAGEMENT, LLC	0.13%	80.36K	3.79M	-61.86K	-43.49%
Jun 30, 2025	CANDRIAM S.C.A.	0.23%	144.83K	6.84M	-29.69K	-17.01%
Jun 30, 2025	RICE HALL JAMES & ASSOCIATES, LLC	0.22%	142.32K	6.72M	4.8K	+3.49%
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	4.13%	2.61M	123.35M	-360.6K	-12.13%
Jun 30, 2025	CITADEL ADVISORS LLC	2.65%	1.67M	79.01M	195.41K	+13.22%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	2.02%	1.28M	60.21M	-17.04K	-1.32%
Jun 30, 2025	NUVEEN, LLC	1.25%	791.56K	37.36M	118.21K	+17.56%
Jun 30, 2025	CATALIO CAPITAL MANAGEMENT, LP	0.26%	162.6K	7.67M	47.98K	+41.86%
Mar 31, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.2%	124.9K	4.88M	-17.8K	-12.47%
Mar 31, 2025	CANDRIAM S.C.A.	0.28%	174.52K	6.82M	-52.96K	-23.28%
Mar 31, 2025	FIRST TURN MANAGEMENT, LLC	0.28%	179.2K	7M	179.2K	+100.00%
Mar 31, 2025	HOLOCENE ADVISORS, LP	0.3%	188.99K	7.38M	-1.4M	-88.08%
Mar 31, 2025	WOODLINE PARTNERS LP	0.47%	296.15K	11.57M	2.61K	+0.89%
Mar 31, 2025	BIOIMPACT CAPITAL LLC	0.5%	316.05K	12.35M	819	+0.26%
Mar 31, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.51%	322.11K	12.58M	-24.5K	-7.07%
Mar 31, 2025	SATURN V CAPITAL MANAGEMENT LLC	0.54%	343.85K	13.43M	-2.26K	-0.65%
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	0.54%	344.32K	13.45M	344.32K	+100.00%
Mar 31, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.62%	392.92K	15.35M	-55.94K	-12.46%
Mar 31, 2025	FINEPOINT CAPITAL LP	0.69%	435.79K	17.03M	-12.15K	-2.71%
Mar 31, 2025	CAMBER CAPITAL MANAGEMENT LP	0.7%	441K	17.23M	0	0
Mar 31, 2025	PARADIGM BIOCAPITAL ADVISORS LP	0.99%	627.42K	24.51M	-1.14M	-64.60%
Mar 31, 2025	MARSHALL WACE, LLP	1.01%	640.92K	25.04M	-604.38K	-48.53%
Mar 31, 2025	FRED ALGER MANAGEMENT, LLC	1.02%	642.88K	25.12M	-30.89K	-4.58%
Mar 31, 2025	ALLIANCEBERNSTEIN L.P.	1.53%	966.09K	37.75M	-56.51K	-5.53%
Mar 31, 2025	POLAR CAPITAL HOLDINGS PLC	1.74%	1.1M	42.98M	0	0
Mar 31, 2025	JANE STREET GROUP, LLC	0.14%	90.8K	3.55M	78.7K	+650.41%
Mar 31, 2025	FEDERATED HERMES, INC.	2.01%	1.27M	49.59M	-10.7K	-0.84%
Mar 31, 2025	AVORO CAPITAL ADVISORS LLC	4.38%	2.77M	108.23M	0	0
Mar 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	4.7%	2.97M	116.19M	-369.81K	-11.06%
Mar 31, 2025	CORMORANT ASSET MANAGEMENT, LP	13.43%	8.49M	331.87M	0	0
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0.14%	91.17K	3.56M	45.63K	+100.21%
Mar 31, 2025	STATE STREET CORP	0.15%	93.4K	3.65M	1.85K	+2.02%
Mar 31, 2025	IKARIAN CAPITAL, LLC	0.15%	94.5K	3.69M	94.5K	+100.00%
Mar 31, 2025	HARBOR CAPITAL ADVISORS, INC.	0.16%	102.02K	3.99M	22.37K	+28.09%
Mar 31, 2025	AXA S.A.	0.16%	104.04K	4.06M	-134	-0.13%
Mar 31, 2025	FRANKLIN RESOURCES INC	0.3%	191.5K	7.48M	191.5K	+100.00%
Mar 31, 2025	VESTAL POINT CAPITAL, LP	0.32%	200K	7.81M	200K	+100.00%
Mar 31, 2025	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.32%	200K	7.81M	0	0
Mar 31, 2025	AMERIPRISE FINANCIAL INC	0.32%	201.52K	7.87M	-2.85K	-1.40%
Mar 31, 2025	TD ASSET MANAGEMENT INC	0.34%	216.9K	8.47M	-44.73K	-17.10%
Mar 31, 2025	VICTORY CAPITAL MANAGEMENT INC	0.41%	258.15K	10.09M	79.65K	+44.62%
Mar 31, 2025	BLACKROCK, INC.	0.45%	286.21K	11.18M	-82.64K	-22.40%
Mar 31, 2025	OCTAGON CAPITAL ADVISORS LP	0.47%	296K	11.56M	296K	+100.00%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	2.04%	1.29M	50.5M	-382.06K	-22.81%
Mar 31, 2025	WESTFIELD CAPITAL MANAGEMENT CO LP	2.27%	1.43M	56.06M	123.15K	+9.39%
Mar 31, 2025	CITADEL ADVISORS LLC	2.34%	1.48M	57.77M	-708.23K	-32.39%
Mar 31, 2025	BVF INC/IL	31.24%	19.75M	771.68M	0	0
Mar 31, 2025	BALYASNY ASSET MANAGEMENT L.P.	0.12%	78.84K	3.08M	-127.73K	-61.84%
Mar 31, 2025	RICE HALL JAMES & ASSOCIATES, LLC	0.22%	137.52K	5.37M	26.38K	+23.74%
Mar 31, 2025	FMR LLC	10.01%	6.33M	247.2M	-14.38K	-0.23%
Mar 31, 2025	CAPTION MANAGEMENT, LLC	0.22%	138.6K	5.42M	138.6K	+100.00%
Mar 31, 2025	GRANAHAN INVESTMENT MANAGEMENT, LLC	0.22%	142.22K	5.56M	5.78K	+4.24%
Mar 31, 2025	HOOD RIVER CAPITAL MANAGEMENT LLC	1.05%	662.98K	25.9M	13.39K	+2.06%
Mar 31, 2025	HUDSON BAY CAPITAL MANAGEMENT LP	0.13%	80K	3.13M	72.5K	+966.67%
Mar 31, 2025	VANGUARD GROUP INC	0.18%	114.02K	4.45M	-1.4K	-1.21%
Mar 31, 2025		0.18%	114.62K	4.48M	114.62K	+100.00%
Mar 31, 2025	UBS GROUP AG	0.19%	120.77K	4.72M	92.85K	+332.58%
Mar 31, 2024	JEFFERIES FINANCIAL GROUP INC.	0.02%	8.8K	442.02K	-8.6K	-49.43%
Mar 31, 2024	STATE OF WISCONSIN INVESTMENT BOARD	0.03%	13.38K	672.28K	-1.71K	-11.34%
Mar 31, 2024	GROUP ONE TRADING, L.P.	0.03%	13.52K	679.11K	13.52K	+100.00%
Mar 31, 2024	SG AMERICAS SECURITIES, LLC	0.03%	14.46K	726K	14.46K	+100.00%
Mar 31, 2024	UBS GROUP AG	0.03%	14.75K	740.99K	14.11K	+2,201.40%
Mar 31, 2024	CREDIT SUISSE AG/	0.04%	19.2K	964.62K	0	0
Mar 31, 2024	RESOLUTE CAPITAL ASSET PARTNERS LLC	0.05%	24.54K	1.23M	24.54K	+100.00%
Mar 31, 2024	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.05%	25.13K	1.26M	7.89K	+45.78%
Mar 31, 2024	CLEARBRIDGE INVESTMENTS, LLC	0.06%	28.55K	1.43M	28.55K	+100.00%
Mar 31, 2024	CENTERBOOK PARTNERS LP	0.06%	29.09K	1.46M	6.31K	+27.71%
Mar 31, 2024	HRT FINANCIAL LP	0.07%	31.94K	1.6M	16.65K	+108.89%
Mar 31, 2024	AVORO CAPITAL ADVISORS LLC	5.25%	2.58M	129.59M	0	0
Mar 31, 2024	BVF INC/IL	44.28%	21.75M	1.09B	0	0
Mar 31, 2024	JANE STREET GROUP, LLC	0.18%	90.17K	4.53M	12.22K	+15.68%
Mar 31, 2024	STEMPOINT CAPITAL LP	0.18%	90.65K	4.55M	-77.2K	-46.00%
Mar 31, 2024	VANGUARD GROUP INC	0.19%	92.3K	4.64M	18.64K	+25.31%
Mar 31, 2024	ROYAL BANK OF CANADA	0.2%	97.47K	4.9M	70.69K	+263.87%
Mar 31, 2024	BLUE OWL CAPITAL HOLDINGS LP	0.2%	100K	5.02M	35K	+53.85%
Mar 31, 2024	AXA S.A.	0.21%	104.26K	5.24M	29	+0.03%
Mar 31, 2024	MONASHEE INVESTMENT MANAGEMENT LLC	0.23%	115K	5.78M	115K	+100.00%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.26%	125.9K	6.32M	38.3K	+43.72%
Mar 31, 2024	MORGAN STANLEY	0.47%	229.18K	11.51M	162.67K	+244.56%
Mar 31, 2024	NATIONALE-NEDERLANDEN POWSZECHNE TOWARZYSTWO EMERYTALNE S.A.	0.47%	229.23K	11.51M	238	+0.10%
Mar 31, 2024	CANDRIAM S.C.A.	0.49%	239K	12M	54K	+29.19%
Mar 31, 2024	WELLINGTON MANAGEMENT GROUP LLP	0.56%	276.44K	13.89M	19.25K	+7.48%
Mar 31, 2024	5AM VENTURE MANAGEMENT, LLC	0.57%	282.31K	14.18M	-20.32K	-6.71%
Mar 31, 2024	BIOIMPACT CAPITAL LLC	0.6%	296.05K	14.87M	1.47K	+0.50%
Mar 31, 2024	GHOST TREE CAPITAL, LLC	0.61%	300K	15.07M	220K	+275.00%
Mar 31, 2024	PERCEPTIVE ADVISORS LLC	0.69%	339.01K	17.03M	256.61K	+311.43%
Mar 31, 2024	FINEPOINT CAPITAL LP	0.73%	360.92K	18.13M	-534.08K	-59.67%
Mar 31, 2024	MARSHALL WACE, LLP	1.04%	510.95K	25.66M	510.95K	+100.00%
Mar 31, 2024	FRED ALGER MANAGEMENT, LLC	1.36%	666.72K	33.49M	-143.86K	-17.75%
Mar 31, 2024	FMR LLC	8.9%	4.37M	219.54M	522.97K	+13.59%
Mar 31, 2024	PARKMAN HEALTHCARE PARTNERS LLC	0.21%	101.07K	5.08M	19.06K	+23.24%
Mar 31, 2024	WALLEYE CAPITAL LLC	0.28%	136.43K	6.85M	136.43K	+100.00%
Mar 31, 2024	SCHONFELD STRATEGIC ADVISORS LLC	0.29%	143.45K	7.21M	-16.95K	-10.57%
Mar 31, 2024	VICTORY CAPITAL MANAGEMENT INC	0.31%	150.65K	7.57M	-3.96K	-2.56%
Mar 31, 2024	IKARIAN CAPITAL, LLC	0.32%	158K	7.94M	-42.6K	-21.24%
Mar 31, 2024	WOODLINE PARTNERS LP	0.42%	207.42K	10.42M	85.66K	+70.36%
Mar 31, 2024	TIMESSQUARE CAPITAL MANAGEMENT, LLC	0.43%	209.49K	10.52M	-279.32K	-57.14%
Mar 31, 2024	GRANAHAN INVESTMENT MANAGEMENT, LLC	0.44%	215.82K	10.84M	89.04K	+70.24%
Mar 31, 2024	BLACKROCK INC.	0.83%	408.28K	20.51M	26.55K	+6.96%
Mar 31, 2024	POLAR CAPITAL HOLDINGS PLC	1.75%	857.96K	43.1M	-79.16K	-8.45%
Mar 31, 2024	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	2.23%	1.1M	55.01M	-125.5K	-10.28%
Mar 31, 2024	HOLOCENE ADVISORS, LP	2.96%	1.45M	73.08M	493.54K	+51.34%
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	4.35%	2.14M	107.29M	-178.13K	-7.70%
Mar 31, 2024	ADAGE CAPITAL PARTNERS GP, L.L.C.	4.65%	2.28M	114.77M	759.2K	+49.76%
Mar 31, 2024	CITADEL ADVISORS LLC	4.7%	2.31M	116M	300.77K	+14.97%
Mar 31, 2024	CORMORANT ASSET MANAGEMENT, LP	17.29%	8.49M	426.66M	0	0
Mar 31, 2024	NORTHERN TRUST CORP	0.01%	5.71K	287.01K	-1.49K	-20.66%
Mar 31, 2024	LPL FINANCIAL LLC	0.01%	6.65K	333.83K	-620	-8.53%
Mar 31, 2024	PEARL RIVER CAPITAL, LLC	0.01%	6.75K	339.05K	2.46K	+57.27%
Mar 31, 2024	PNC FINANCIAL SERVICES GROUP, INC.	0.01%	6.81K	342.27K	667	+10.85%
Mar 31, 2024	HARBOR CAPITAL ADVISORS, INC.	0.02%	8.21K	412K	8.21K	+100.00%
Mar 31, 2024	NEW YORK STATE COMMON RETIREMENT FUND	0.02%	8.27K	415K	8.18K	+8,983.52%
Mar 31, 2024	ENVESTNET ASSET MANAGEMENT INC	0.02%	8.44K	424.04K	-675	-7.40%
Mar 31, 2024	TREXQUANT INVESTMENT LP	0.02%	9.7K	487.08K	9.7K	+100.00%
Mar 31, 2024	QUBE RESEARCH & TECHNOLOGIES LTD	0.02%	11.3K	567.6K	11.3K	+100.00%
Mar 31, 2024	ALLIANZ ASSET MANAGEMENT GMBH	0.03%	12.3K	617.83K	0	0
Mar 31, 2024	SWISS NATIONAL BANK	0.07%	35.3K	1.77M	0	0
Mar 31, 2024	ALPS ADVISORS INC	0.09%	42.27K	2.12M	3.38K	+8.68%
Mar 31, 2024	SECTORAL ASSET MANAGEMENT INC	0.09%	46.3K	2.33M	16.29K	+54.29%
Mar 31, 2024	ENSIGN PEAK ADVISORS, INC	0.11%	53.19K	2.67M	-461	-0.86%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	0.11%	54.03K	2.71M	5.25K	+10.77%
Mar 31, 2024	AFFINITY ASSET ADVISORS, LLC	0.15%	75K	3.77M	4.01K	+5.65%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.17%	82.83K	4.16M	-1.09K	-1.30%
Mar 31, 2024	BALYASNY ASSET MANAGEMENT L.P.	0.86%	424.7K	21.33M	-173.82K	-29.04%
Mar 31, 2024	PICTET ASSET MANAGEMENT HOLDING SA	1.02%	499.84K	25.11M	-116.72K	-18.93%
Mar 31, 2024	WESTFIELD CAPITAL MANAGEMENT CO LP	1.85%	910.87K	45.75M	298.82K	+48.82%
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	1.95%	955.51K	48M	46.36K	+5.10%
Mar 31, 2024	FEDERATED HERMES, INC.	2.24%	1.1M	55.24M	39.23K	+3.70%
Mar 31, 2024	LORD, ABBETT & CO. LLC	0.18%	86.49K	4.34M	-72.83K	-45.71%
Mar 31, 2024	DUQUESNE FAMILY OFFICE LLC	0.18%	87.5K	4.4M	87.5K	+100.00%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.32%	158.16K	7.94M	7.03K	+4.65%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.4%	195.87K	9.84M	-444	-0.23%
Mar 31, 2024	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.41%	200K	10.05M	200K	+100.00%
Mar 31, 2024	TD ASSET MANAGEMENT INC	0.42%	204.09K	10.25M	-5.05K	-2.41%
Dec 31, 2023	FRED ALGER MANAGEMENT, LLC	1.51%	810.59K	48.95M	-22.37K	-2.69%
Dec 31, 2023	ALLIANCEBERNSTEIN L.P.	1.7%	909.15K	54.9M	437.83K	+92.89%
Dec 31, 2023	POLAR CAPITAL HOLDINGS PLC	1.75%	937.12K	56.59M	-1.9K	-0.20%
Dec 31, 2023	HOLOCENE ADVISORS, LP	1.8%	961.33K	58.05M	855.51K	+808.44%
Dec 31, 2023	DARWIN GLOBAL MANAGEMENT, LTD.	1.94%	1.04M	62.76M	1.04M	+100.00%
Dec 31, 2023	FEDERATED HERMES, INC.	1.98%	1.06M	64.05M	-23.72K	-2.19%
Dec 31, 2023	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	2.28%	1.22M	73.71M	5.88K	+0.48%
Dec 31, 2023	ADAGE CAPITAL PARTNERS GP, L.L.C.	2.85%	1.53M	92.14M	-426.99K	-21.87%
Dec 31, 2023	CITADEL ADVISORS LLC	3.75%	2.01M	121.3M	-25.74K	-1.27%
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	4.32%	2.31M	139.74M	196.14K	+9.26%
Dec 31, 2023	AVORO CAPITAL ADVISORS LLC	4.82%	2.58M	155.81M	580K	+29.00%
Dec 31, 2023	FMR LLC	7.19%	3.85M	232.36M	450.43K	+13.26%
Dec 31, 2023	CORMORANT ASSET MANAGEMENT, LP	15.87%	8.49M	512.96M	352.05K	+4.32%
Dec 31, 2023	BVF INC/IL	40.64%	21.75M	1.31B	0	0
Dec 31, 2023	PARKMAN HEALTHCARE PARTNERS LLC	0.15%	82.01K	4.95M	28.72K	+53.88%
Dec 31, 2023	PERCEPTIVE ADVISORS LLC	0.15%	82.4K	4.98M	82.4K	+100.00%
Dec 31, 2023	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.16%	83.92K	5.07M	10.21K	+13.85%
Dec 31, 2023	SOROS FUND MANAGEMENT LLC	0.19%	100K	6.04M	44K	+78.57%
Dec 31, 2023	AXA S.A.	0.19%	104.23K	6.29M	-19.17K	-15.53%
Dec 31, 2023	TIG ADVISORS, LLC	0.2%	105.9K	6.4M	105.9K	+100.00%
Dec 31, 2023	SOFINNOVA INVESTMENTS, INC.	0.21%	113.76K	6.87M	-179.05K	-61.15%
Dec 31, 2023	WOODLINE PARTNERS LP	0.23%	121.75K	7.35M	20.01K	+19.66%
Dec 31, 2023	GRANAHAN INVESTMENT MANAGEMENT, LLC	0.24%	126.77K	7.66M	42.21K	+49.92%
Dec 31, 2023	D. E. SHAW & CO., INC.	0.24%	128.7K	7.77M	128.7K	+100.00%
Dec 31, 2023	ALLY BRIDGE GROUP (NY) LLC	0.27%	143.48K	8.66M	-39.63K	-21.64%
Dec 31, 2023	LOGOS GLOBAL MANAGEMENT LP	0.28%	150K	9.06M	150K	+100.00%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.28%	151.13K	9.13M	54.45K	+56.31%
Dec 31, 2023	VICTORY CAPITAL MANAGEMENT INC	0.29%	154.61K	9.34M	-28.37K	-15.50%
Dec 31, 2023	SENATOR INVESTMENT GROUP LP	0.29%	155K	9.36M	155K	+100.00%
Dec 31, 2023	LORD, ABBETT & CO. LLC	0.3%	159.32K	9.62M	-16.72K	-9.50%
Dec 31, 2023	FINEPOINT CAPITAL LP	1.67%	895K	62.74K	563.58K	+170.05%
Dec 31, 2023	SCHONFELD STRATEGIC ADVISORS LLC	0.3%	160.4K	9.69M	-180.3K	-52.92%
Dec 31, 2023	CANDRIAM S.C.A.	0.35%	185K	11.17M	185K	+100.00%
Dec 31, 2023	NUVEEN ASSET MANAGEMENT, LLC	0.37%	196.32K	11.86M	56.32K	+40.23%
Dec 31, 2023	CAPTION MANAGEMENT, LLC	0.37%	200K	12.08M	-180.9K	-47.49%
Dec 31, 2023	IKARIAN CAPITAL, LLC	0.37%	200.6K	12.11M	200.6K	+100.00%
Dec 31, 2023	TD ASSET MANAGEMENT INC	0.39%	209.14K	12.63M	8.75K	+4.37%
Dec 31, 2023	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.41%	220K	13.29M	-280K	-56.00%
Dec 31, 2023	INVESCO LTD.	0.45%	238.23K	14.39M	-12K	-4.80%
Dec 31, 2023	GHOST TREE CAPITAL, LLC	0.47%	250K	15.1M	250K	+100.00%
Dec 31, 2023	WELLINGTON MANAGEMENT GROUP LLP	0.48%	257.19K	15.53M	257.19K	+100.00%
Dec 31, 2023	BIOIMPACT CAPITAL LLC	0.55%	294.58K	17.79M	386	+0.13%
Dec 31, 2023	5AM VENTURE MANAGEMENT, LLC	0.57%	302.63K	18.28M	-10.58K	-3.38%
Dec 31, 2023	BLACKROCK INC.	0.71%	381.73K	23.05M	-367.15K	-49.03%
Dec 31, 2023	TIMESSQUARE CAPITAL MANAGEMENT, LLC	0.91%	488.81K	29.52M	77.59K	+18.87%
Dec 31, 2023	BALYASNY ASSET MANAGEMENT L.P.	1.12%	598.51K	36.14M	364.26K	+155.50%
Dec 31, 2023	WESTFIELD CAPITAL MANAGEMENT CO LP	1.14%	612.05K	36.96M	220.77K	+56.42%
Dec 31, 2023		0.31%	167.85K	10.14M	167.85K	+100.00%

Insiders

Among the MLTX insiders holding of 10.41% of the stake in company, SANTOS DA SILVA JORGE, Chief Executive Officer, holds the largest shares of 2.92M. REICH KRISTIAN, Chief Scientific Officer, is the second largest MLTX insider with ownership of 2.82M shares. CHEN BIHUA, Former 10% Owner, stands third with possession of 1.99M shares of that stake.

Insiders	Designation	Shares Held
SANTOS DA SILVA JORGE	Chief Executive Officer	2.92M
REICH KRISTIAN	Chief Scientific Officer	2.82M
CHEN BIHUA	Former 10% Owner	1.99M
BODENSTEDT MATTHIAS	Chief Financial Officer	1.15M
BVF PARTNERS L P/IL		1.04M
HELIX HOLDINGS LLC		430K
STURGE SIMON	director	171.98K
MOUKHEIBIR CATHERINE	director	0

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Jun 18, 2026	BODENSTEDT MATTHIAS	SALE	19.60	2.79K	54.76K	1.15M
Jun 17, 2026	BODENSTEDT MATTHIAS	SALE	19.68	15.08K	296.81K	1.16M
Jun 17, 2026	REICH KRISTIAN	SALE	19.43	50K	971.5K	2.82M
Jun 16, 2026	REICH KRISTIAN	SALE	18.70	50K	935K	2.87M
Jun 15, 2026	REICH KRISTIAN	SALE	18.89	50K	944.5K	2.92M
May 11, 2026	BODENSTEDT MATTHIAS	SALE	20.02	13.65K	273.33K	1.17M
Apr 14, 2026	BODENSTEDT MATTHIAS	SALE	19.56	2.43K	47.45K	1.19M
Apr 13, 2026	SANTOS DA SILVA JORGE	SALE	18.23	51.87K	945.64K	2.92M
Apr 10, 2026	BODENSTEDT MATTHIAS	SALE	19.51	1.93K	37.56K	1.19M
Apr 10, 2026	SANTOS DA SILVA JORGE	SALE	18.41	98.13K	1.81M	2.98M
Apr 09, 2026	BODENSTEDT MATTHIAS	SALE	18.94	85.87K	1.63M	1.19M
Mar 31, 2026	BVF PARTNERS L P/IL	SALE	16.79	248.53K	4.17M	1.04M
Dec 09, 2025	SANTOS DA SILVA JORGE	SALE	14.49	70K	1.01M	2.88M
Dec 09, 2025	REICH KRISTIAN	SALE	14.43	72.91K	1.05M	0
Dec 08, 2025	SANTOS DA SILVA JORGE	SALE	15.08	130K	1.96M	2.95M
Dec 08, 2025	REICH KRISTIAN	SALE	15.08	130K	1.96M	72.91K
Oct 08, 2025	BODENSTEDT MATTHIAS	PURCHASE	9.09	10.87K	98.81K	627.54K
Sep 30, 2025	CHEN BIHUA	SALE	6.96	5.83K	40.56K	1.99M
Sep 29, 2025	CHEN BIHUA	SALE	6.61	2.8M	18.51M	2M
Jul 03, 2025	MOUKHEIBIR CATHERINE	SALE	48.79	23.5K	1.15M	0
Oct 04, 2024	STURGE SIMON	SALE	53.72	171K	9.19M	171.98K
Oct 04, 2024	BVF PARTNERS L P/IL	SALE	50.00	132.55K	6.63M	1.29M
Feb 29, 2024	SANTOS DA SILVA JORGE	SALE	55.89	4.74K	264.92K	2.98M
Feb 28, 2024	REICH KRISTIAN	SALE	55.00	28.09K	1.54M	41.98K
Feb 28, 2024	SANTOS DA SILVA JORGE	SALE	55.00	56.07K	3.08M	2.99M
Feb 27, 2024	SANTOS DA SILVA JORGE	SALE	55.00	62.81K	3.45M	3.04M
Feb 27, 2024	REICH KRISTIAN	SALE	55.00	29.43K	1.62M	70.07K
Feb 21, 2024	SANTOS DA SILVA JORGE	SALE	55.27	1.13K	62.18K	3.11M
Feb 21, 2024	REICH KRISTIAN	SALE	55.30	569	31.47K	99.5K
Feb 20, 2024	REICH KRISTIAN	SALE	57.43	10K	574.3K	100.07K
Feb 20, 2024	SANTOS DA SILVA JORGE	SALE	57.44	20K	1.15M	3.11M
Feb 16, 2024	SANTOS DA SILVA JORGE	SALE	60.15	20K	1.2M	3.13M
Feb 16, 2024	REICH KRISTIAN	SALE	60.15	10K	601.5K	110.07K
Feb 15, 2024	REICH KRISTIAN	SALE	60.16	10K	601.6K	120.07K
Feb 15, 2024	SANTOS DA SILVA JORGE	SALE	60.18	20K	1.2M	3.15M
Feb 14, 2024	REICH KRISTIAN	SALE	62.43	10K	624.3K	130.07K
Dec 20, 2023	BODENSTEDT MATTHIAS	SALE	58.34	5.26K	307.1K	520.9K
Dec 19, 2023	BODENSTEDT MATTHIAS	SALE	59.22	94.74K	5.61M	526.17K
Oct 05, 2023	CHEN BIHUA	PURCHASE	59.90	58.84K	3.52M	8.49M
Oct 04, 2023	CHEN BIHUA	PURCHASE	57.32	67.81K	3.89M	8.44M
Oct 03, 2023	CHEN BIHUA	PURCHASE	57.25	150.49K	8.62M	8.37M
Oct 02, 2023	CHEN BIHUA	PURCHASE	57.37	74.91K	4.3M	8.22M
Jun 30, 2023	CHEN BIHUA	PURCHASE	50.00	800K	40M	4.93M
Jun 26, 2023	CHEN BIHUA	PURCHASE	36.91	1.48K	54.66K	3.68M
Apr 05, 2022	CHEN BIHUA	PURCHASE	10.00	2.85M	28.5M	2.85M
Oct 22, 2020	CHEN BIHUA	PURCHASE	10.00	430K	4.3M	430K
Oct 22, 2020	HELIX HOLDINGS LLC	PURCHASE	10.00	430K	4.3M	430K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES670.28K12

NET SHARES-670.28K12

SHARES HELD22.61M12

% NET SHARES-102.96%0%

Frequently Asked Questions