How many institutions own LYEL stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own LYEL shares is 93, representing 50.02% of the company's common stock.

Who are the major shareholders selling Lyell Immunopharma, Inc. stock?

BOOTHBAY FUND MANAGEMENT, LLC, in the last quarter, reduced its stake in LYEL by -22.22% restricting it's holding to 9.52 thousand shares of worth nearly $292.90K. TWO SIGMA INVESTMENTS, LP also lessened -25.02% of the LYEL shares from its portfolio, reducing its holding to 15.62 thousand shares of worth $480.66K. RENAISSANCE TECHNOLOGIES LLC also shunned LYEL shares holding by -38.29% last quarter which brought its holding to 39.49 thousand shares worth $1.22M.

Investors who are buying LYEL stock?

As per its latest 13F filing, QUBE RESEARCH & TECHNOLOGIES LTD increased its stake in LYEL by 100% in the last quarter. The institutional holder raised its holding to 9.05 thousand shares having worth more than $278.59K. JANE STREET GROUP, LLC also added 100% more shares of LYEL to its portfolio, raising its holding to 12.41 thousand shares of worth $381.95K. CANADA PENSION PLAN INVESTMENT BOARD also increased its LYEL shares holding by 9.18% which brought its holding to 32.11 thousand shares worth $988.38K.

LYEL's major insiders: who are they?

The insider with the most stakes in LYEL is ARCH Venture Partners IX, LLC , 10 percent owner at the company. Additionally, LYEL stock is highly held by 10 percent owner ARCH Venture Fund XIII, L.P. and director Klausner Richard among others.

Did an insider recently sell LYEL stock?

Company executives, directors, and other insiders own 20.56% percent of Lyell Immunopharma, Inc.'s stock. Within the last six months, there have been 13 transaction(s) in which LYEL insiders have sold stock, totaling 14.27K shares. Insiders that have sold shares include SEELY LYNN, LEE GARY K., and HILL STEPHEN J..

Which insider recently purchased LYEL stock?

There have been 2 transaction(s) during the past 6-months in which Lyell Immunopharma, Inc. insiders have bought stock, totalling 976180 shares

How much of LYEL does insiders own?

Around 3.22M Lyell Immunopharma, Inc. shares are held by insiders, which represents about 20.56% of LYEL stock.

Who is the insider with the largest stake?

LYEL 10 percent owner, ARCH Venture Partners IX, LLC holds the largest portfolio of the company's shares. LYEL shares owned by ARCH total nearly 1.43 million.

Which institution holds the most shares in LYEL?

BOOTHBAY FUND MANAGEMENT, LLC is the largest institutional owner in LYEL which holds 9.52 thousand shares worth $292.90K or 0.05% of the total LYEL shares outstanding followed by QUBE RESEARCH & TECHNOLOGIES LTD with ownership of 9.05 thousand shares representing 0.05% of the LYEL ownership. JANE STREET GROUP, LLC is the third largest stakeholder with 12.41 thousand shares or 0.07% of the ownership worth more than $381.95K.

Is Lyell Immunopharma, Inc. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the LYEL is concerned, it is a stock which is optionable.

Is there a short position on LYEL's shares?

Number of LYEL shares short is 132.97K. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding LYEL shares are there?

As of today, 19.21M shares of LYEL are outstanding.

Is there many float in LYEL stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, LYEL has 12.05M shares in float.

LYEL short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for LYEL is 2.04.

Lyell Immunopharma (LYEL) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares0.69

Short Percent Of Float0.85

Shares Outstanding19.21M

Shares Float12.05M

Shares Short132.97K

Short Ratio2.04

0.85%

Short % of Float

0.69%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

20.56% Percentage of Shares held by All Insiders

50.02% Percentage of Shares held by All Institutions

62.96% Percentage of Float held by Institutions

Number of Institutions Holding Shares

Institutional Ownership

About 50.02% of LYEL shares are held by financial institutions. BOOTHBAY FUND MANAGEMENT, LLC is the top corporate investor, holding 9.52K shares valued at $292.90K. A 0.05% stake in Lyell Immunopharma, Inc. is owned by the company. QUBE RESEARCH & TECHNOLOGIES LTD owns 9.05K shares valued at $278.59K, which translates its holding of 0.05% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Dec 31, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.05%	9.52K	292.9K	-2.72K	-22.22%
Dec 31, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.05%	9.05K	278.59K	9.05K	+100.00%
Dec 31, 2025	JANE STREET GROUP, LLC	0.07%	12.41K	381.95K	12.41K	+100.00%
Dec 31, 2025	TWO SIGMA INVESTMENTS, LP	0.09%	15.62K	480.66K	-5.21K	-25.02%
Dec 31, 2025	CANADA PENSION PLAN INVESTMENT BOARD	0.18%	32.11K	988.38K	2.7K	+9.18%
Dec 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0.22%	39.49K	1.22M	-24.5K	-38.29%
Dec 31, 2025	CITADEL ADVISORS LLC	0.09%	16K	492.48K	-750	-4.48%
Dec 31, 2025	CLARIUS GROUP, LLC	0.11%	19.96K	614.31K	0	0
Dec 31, 2025	IKARIAN CAPITAL, LLC	0.22%	41.08K	1.26M	-2.72K	-6.21%
Dec 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.47%	85.42K	2.63M	5.91K	+7.44%
Dec 31, 2025	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.05%	8.51K	261.97K	8.51K	+100.00%
Dec 31, 2025	BANK OF AMERICA CORP /DE/	0.04%	8.05K	247.63K	3.37K	+71.94%
Dec 31, 2025	RAYMOND JAMES FINANCIAL INC	0.04%	7.9K	243.16K	7.9K	+100.00%
Dec 31, 2025	DIADEMA PARTNERS LP	0.02%	3.8K	116.96K	3.8K	+100.00%
Dec 31, 2025	VENBIO PARTNERS LLC	1.85%	337.7K	10.39M	-135.78K	-28.68%
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.89%	163K	5.02M	32.74K	+25.13%
Dec 31, 2025	INVESCO LTD.	0.54%	98.65K	3.04M	98.65K	+100.00%
Dec 31, 2025	NORTHERN TRUST CORP	0.17%	30.28K	932.02K	2.15K	+7.65%
Dec 31, 2025	SUSQUEHANNA PORTFOLIO STRATEGIES, LLC	0.11%	20.8K	640.22K	0	0
Dec 31, 2025	BBR PARTNERS, LLC	0.04%	6.83K	210.35K	6.83K	+100.00%
Dec 31, 2025	ORLAND PROPERTIES LTD	4.13%	754.7K	23.23M	0	0
Dec 31, 2025	FORESITE CAPITAL MANAGEMENT V, LLC	2.61%	477.08K	14.68M	0	0
Dec 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.05%	8.4K	258.55K	8.4K	+100.00%
Dec 31, 2025	GOLDMAN SACHS GROUP INC	0.53%	96.68K	2.98M	96.68K	+100.00%
Dec 31, 2025	JOHNSON & JOHNSON	0.3%	54.89K	1.69M	0	0
Dec 31, 2025	CITIGROUP INC	0.02%	4.23K	130.29K	3.2K	+310.97%
Dec 31, 2025	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.02%	3.46K	106.41K	90	+2.67%
Dec 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.02%	3.17K	97.57K	2.82K	+792.96%
Dec 31, 2025	ACADIAN ASSET MANAGEMENT LLC	0.01%	1.66K	51K	-9.73K	-85.45%
Dec 31, 2025	JPMORGAN CHASE & CO	0.01%	1.62K	49.74K	1.13K	+229.80%
Dec 31, 2025	MIRAE ASSET GLOBAL INVESTMENTS CO., LTD.	0.01%	1.03K	31.73K	288	+38.76%
Dec 31, 2025	JONES FINANCIAL COMPANIES LLLP	0.01%	1.03K	31.55K	-975	-48.75%
Dec 31, 2025	ADVISORS ASSET MANAGEMENT, INC.	0%	567	17.45K	0	0
Dec 31, 2025	GF FUND MANAGEMENT CO. LTD.	0%	416	12.8K	3	+0.73%
Dec 31, 2025	WELLS FARGO & COMPANY/MN	0%	125	3.85K	125	+100.00%
Dec 31, 2025	GSK PLC	8.28%	1.51M	46.56M	1.51M	+100.00%
Dec 31, 2025	MAI CAPITAL MANAGEMENT	0%	100	3.08K	0	0
Dec 31, 2025	US BANCORP \DE\	0%	58	1.79K	0	0
Dec 31, 2025		5.52%	1.01M	31.03B	1.01M	+100.00%
Dec 31, 2025	NISA INVESTMENT ADVISORS, LLC	0%	25	770	0	0
Dec 31, 2025	GAMMA INVESTING LLC	0%	35	1.08K	0	0
Dec 31, 2025	SIMPLEX TRADING, LLC	0%	37	1.14K	-125	-77.16%
Dec 31, 2025	ADVISOR GROUP HOLDINGS, INC.	0%	124	3.82K	124	+100.00%
Dec 31, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0.01%	1.19K	36.75M	-664	-35.74%
Dec 31, 2025	CANDRIAM S.C.A.	0.04%	7.62K	234.46K	7.62K	+100.00%
Dec 31, 2025	UBS GROUP AG	0.07%	13.2K	406.39K	-8.04K	-37.84%
Dec 31, 2025	DAIWA SECURITIES GROUP INC.	0%	45	1K	0	0
Dec 31, 2025	ROYAL BANK OF CANADA	0%	24	1K	-4.16K	-99.43%
Dec 31, 2025	CWM, LLC	0%	20	1K	-22	-52.38%
Dec 31, 2025	ORBIMED ADVISORS LLC	0%	0	-	-51.73K	-100.00%
Dec 31, 2025	RANGELEY CAPITAL, LLC	0%	0	-	-10K	-100.00%
Dec 31, 2025	TREXQUANT INVESTMENT LP	0%	0	-	-10.28K	-100.00%
Dec 31, 2025	IFP ADVISORS, INC	0%	0	-	-1	-100.00%
Dec 31, 2025	MIC CAPITAL MANAGEMENT UK LLP	0.48%	87.03K	2.68M	0	0
Dec 31, 2025	MARSHALL WACE, LLP	0.4%	73.32K	2.26M	73.32K	+100.00%
Dec 31, 2025	ARCH VENTURE MANAGEMENT, LLC	15.1%	2.76M	84.92M	0	0
Dec 31, 2025	MILLENNIUM MANAGEMENT LLC	0.32%	58.65K	1.81M	-66.71K	-53.21%
Dec 31, 2025	STATE STREET CORP	0.28%	51.47K	1.58M	17.72K	+52.50%
Dec 31, 2025	MORGAN STANLEY	0.24%	42.95K	1.32M	5.93K	+16.02%
Dec 31, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.1%	18K	554.04K	0	0
Dec 31, 2025	BARCLAYS PLC	0.09%	15.97K	491.47K	14.78K	+1,239.51%
Dec 31, 2025	VANGUARD GROUP INC	4.52%	826.43K	25.44M	47.43K	+6.09%
Dec 31, 2025	ALPHABET INC.	1.61%	293.26K	9.03M	0	0
Dec 31, 2025	BLACKROCK, INC.	1%	181.84K	5.6M	5.03K	+2.85%
Dec 31, 2025	SC CHINA HOLDING LTD	0.83%	152.3K	3.94M	0	0
Dec 31, 2025	RBF CAPITAL, LLC	0.41%	74.59K	2.3M	-21.05K	-22.01%
Dec 31, 2025	FORESITE CAPITAL MANAGEMENT IV, LLC	4.38%	800.4K	24.64M	0	0
Dec 31, 2025	ALMITAS CAPITAL LLC	3.16%	577.81K	17.78M	0	0
Dec 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	0.07%	13.13K	405K	0	0
Dec 31, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.06%	11.48K	353.35K	11.48K	+100.00%
Sep 30, 2025	BLACKROCK, INC.	1.2%	176.81K	2.87M	31.95K	+22.05%
Sep 30, 2025	US BANCORP \DE\	0%	58	942	0	0
Sep 30, 2025	MAI CAPITAL MANAGEMENT	0%	100	1.62K	0	0
Sep 30, 2025	SIMPLEX TRADING, LLC	0%	162	2K	-136	-45.64%
Sep 30, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0.01%	1.86K	30.17K	-245	-11.65%
Sep 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.11%	16.16K	262.42K	16.16K	+100.00%
Sep 30, 2025	CITADEL ADVISORS LLC	0.11%	16.75K	272.02K	760	+4.75%
Sep 30, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.12%	18K	292.32K	0	0
Sep 30, 2025	TWO SIGMA INVESTMENTS, LP	0.14%	20.83K	338.23K	10.77K	+107.05%
Sep 30, 2025	UBS GROUP AG	0.14%	21.24K	344.97K	-4.39K	-17.13%
Sep 30, 2025	JONES FINANCIAL COMPANIES LLLP	0.01%	2K	25.66K	0	0
Sep 30, 2025	ROYAL BANK OF CANADA	0.03%	4.19K	68K	4.19K	+100.00%
Sep 30, 2025	NORTHERN TRUST CORP	0.19%	28.13K	456.8K	9.48K	+50.87%
Sep 30, 2025	CANADA PENSION PLAN INVESTMENT BOARD	0.2%	29.41K	477.64K	0	0
Sep 30, 2025	MIC CAPITAL MANAGEMENT UK LLP	0.59%	87.03K	1.41M	0	0
Sep 30, 2025	JOHNSON & JOHNSON	0.28%	41.17K	668.52K	41.17K	+100.00%
Sep 30, 2025	ORLAND PROPERTIES LTD	5.1%	754.7K	12.26M	754.7K	+100.00%
Sep 30, 2025	ARCH VENTURE MANAGEMENT, LLC	18.65%	2.76M	44.81M	938.44K	+51.54%
Sep 30, 2025	VANGUARD GROUP INC	5.27%	779K	12.65M	336.38K	+76.00%
Sep 30, 2025	MWG MANAGEMENT LTD.	6.81%	1.01M	16.37M	1.01M	+100.00%
Sep 30, 2025	VSM WEALTH ADVISORY, LLC	0%	0	-	-250	-100.00%
Sep 30, 2025	TRUE WEALTH DESIGN, LLC	0%	0	-	-23	-100.00%
Sep 30, 2025	EVERSOURCE WEALTH ADVISORS, LLC	0%	0	-	-1	-100.00%
Sep 30, 2025	MARSHALL WACE, LLP	0%	0	-	-10.58K	-100.00%
Sep 30, 2025	SHELL ASSET MANAGEMENT CO	0%	0	-	-320	-100.00%
Sep 30, 2025	TD ASSET MANAGEMENT INC	0%	0	-	-50.23K	-100.00%
Sep 30, 2025	INVESCO LTD.	0%	0	-	-12.81K	-100.00%
Sep 30, 2025	PNC FINANCIAL SERVICES GROUP, INC.	0%	0	-	-4	-100.00%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0%	0	-	-1.97K	-100.00%
Sep 30, 2025	NISA INVESTMENT ADVISORS, LLC	0%	25	406	0	0
Sep 30, 2025	GAMMA INVESTING LLC	0%	35	568	0	0
Sep 30, 2025	FMR LLC	0.02%	2.72K	44.21K	-355	-11.54%
Sep 30, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.08%	12.23K	198.68K	0	0
Sep 30, 2025	RBF CAPITAL, LLC	0.65%	95.63K	1.55M	-4.37K	-4.37%
Sep 30, 2025	MILLENNIUM MANAGEMENT LLC	0.85%	125.36K	2.04M	73.13K	+140.02%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.88%	130.26K	2.12M	26.99K	+26.13%
Sep 30, 2025	DAIWA SECURITIES GROUP INC.	0%	45	1K	45	+100.00%
Sep 30, 2025	ALPHABET INC.	1.98%	293.26K	4.76M	0	0
Sep 30, 2025	FORESITE CAPITAL MANAGEMENT V, LLC	3.23%	477.08K	7.75M	70.43K	+17.32%
Sep 30, 2025	STATE STREET CORP	0.23%	33.75K	548.13K	-95	-0.28%
Sep 30, 2025	MORGAN STANLEY	0.25%	37.02K	601.2K	11.32K	+44.06%
Sep 30, 2025	IKARIAN CAPITAL, LLC	0.3%	43.8K	711.3K	0	0
Sep 30, 2025	ORBIMED ADVISORS LLC	0.35%	51.73K	840.05K	0	0
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.43%	63.99K	1.04M	-3.2K	-4.76%
Sep 30, 2025	ALMITAS CAPITAL LLC	3.91%	577.81K	9.38M	-2.19K	-0.38%
Sep 30, 2025	FORESITE CAPITAL MANAGEMENT IV, LLC	5.41%	800.4K	13M	0	0
Sep 30, 2025	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.02%	3.37K	54.68K	401	+13.52%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.54%	79.51K	1.29M	18.01K	+29.28%
Sep 30, 2025	CLARIUS GROUP, LLC	0.13%	19.96K	324.12K	820	+4.28%
Sep 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	0.09%	13.13K	214K	-292.93K	-95.71%
Sep 30, 2025	TREXQUANT INVESTMENT LP	0.07%	10.28K	166.87K	10.28K	+100.00%
Sep 30, 2025	RANGELEY CAPITAL, LLC	0.07%	10K	162.4K	10K	+100.00%
Sep 30, 2025	SUSQUEHANNA PORTFOLIO STRATEGIES, LLC	0.14%	20.8K	337.79K	-900	-4.15%
Sep 30, 2025	ACADIAN ASSET MANAGEMENT LLC	0.08%	11.39K	184K	-15.98K	-58.38%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.03%	4.68K	75.99K	-19.08K	-80.31%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0%	355	5.77K	2	+0.57%
Sep 30, 2025	GF FUND MANAGEMENT CO. LTD.	0%	413	6.71K	413	+100.00%
Sep 30, 2025	JPMORGAN CHASE & CO	0%	490	7.96K	-2.88K	-85.46%
Sep 30, 2025	ADVISORS ASSET MANAGEMENT, INC.	0%	567	9.21K	-8	-1.39%
Sep 30, 2025	MIRAE ASSET GLOBAL INVESTMENTS CO., LTD.	0.01%	743	12.07K	173	+30.35%
Sep 30, 2025	CITIGROUP INC	0.01%	1.03K	16.73K	-1.03K	-49.88%
Sep 30, 2025	BARCLAYS PLC	0.01%	1.19K	19.36K	37	+3.20%
Sep 30, 2025	SC CHINA HOLDING LTD	1.03%	152.3K	73.1K	0	0
Sep 30, 2025	VENBIO PARTNERS LLC	3.2%	473.48K	7.69M	0	0
Sep 30, 2025	CWM, LLC	0%	42	1K	-373	-89.88%
Jun 30, 2025	IKARIAN CAPITAL, LLC	0.01%	43.8K	387.18K	43.8K	+100.00%
Jun 30, 2025	VENBIO PARTNERS LLC	0.16%	473.48K	4.19M	473.48K	+100.00%
Jun 30, 2025	ALMITAS CAPITAL LLC	0.2%	580K	5.13M	580K	+100.00%
Jun 30, 2025	WALLEYE CAPITAL LLC	0.2%	29.23K	258.39K	29.23K	+100.00%
Jun 30, 2025	ORLAND PROPERTIES LTD	0.26%	754.7K	6.67M	-14.34M	-95.00%
Jun 30, 2025	INVESCO LTD.	0.09%	12.81K	113.23K	12.81K	+100.00%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0.16%	23.76K	210.02K	23.76K	+100.00%
Jun 30, 2025	STATE STREET CORP	0.23%	33.85K	299.21K	33.85K	+100.00%
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	0.1%	306.06K	2.71M	306.06K	+100.00%
Jun 30, 2025	NORTHERN TRUST CORP	0.13%	18.64K	164.81K	18.64K	+100.00%
Jun 30, 2025	CLARIUS GROUP, LLC	0.01%	19.14K	169.18K	19.14K	+100.00%
Jun 30, 2025	GAMMA INVESTING LLC	0%	35	309	35	+100.00%
Jun 30, 2025	US BANCORP \DE\	0%	0	-	-1.17K	-100.00%
Jun 30, 2025	JPMORGAN CHASE & CO	0%	0	-	-194.65K	-100.00%
Jun 30, 2025	EVERSOURCE WEALTH ADVISORS, LLC	0%	1	9	1	+100.00%
Jun 30, 2025	TRUE WEALTH DESIGN, LLC	0%	23	204	23	+100.00%
Jun 30, 2025	NISA INVESTMENT ADVISORS, LLC	0%	25	221	25	+100.00%
Jun 30, 2025	MIRAE ASSET GLOBAL INVESTMENTS CO., LTD.	0%	570	5.04K	570	+100.00%
Jun 30, 2025	FMR LLC	0.02%	3.08K	27.2K	3.08K	+100.00%
Jun 30, 2025	MORGAN STANLEY	0.17%	25.7K	227.17K	25.7K	+100.00%
Jun 30, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.17%	24.42K	215.86K	24.42K	+100.00%
Jun 30, 2025	VANGUARD GROUP INC	0.15%	442.63K	3.91M	442.63K	+100.00%
Jun 30, 2025	CITADEL ADVISORS LLC	0.11%	15.99K	141.35K	15.99K	+100.00%
Jun 30, 2025	SC CHINA HOLDING LTD	0.05%	152.3K	1.35M	152.3K	+100.00%
Jun 30, 2025	BLACKROCK, INC.	0.05%	144.86K	1.28M	144.86K	+100.00%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.04%	103.27K	913.26K	103.27K	+100.00%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.02%	61.5K	543.69K	61.5K	+100.00%
Jun 30, 2025	ORBIMED ADVISORS LLC	0.02%	51.73K	457.27K	51.73K	+100.00%
Jun 30, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0.01%	2.1K	18.59K	2.1K	+100.00%
Jun 30, 2025	JOHNSON & JOHNSON	0.01%	41.17K	368.02K	-782.15K	-95.00%
Jun 30, 2025	CITIGROUP INC	0.01%	2.06K	18.17K	2.06K	+100.00%
Jun 30, 2025	CANADA PENSION PLAN INVESTMENT BOARD	0.01%	29.41K	259.99K	29.41K	+100.00%
Jun 30, 2025	TD ASSET MANAGEMENT INC	0.02%	50.23K	444.05K	50.23K	+100.00%
Jun 30, 2025	MIC CAPITAL MANAGEMENT UK LLP	0.03%	87.03K	769.33K	87.03K	+100.00%
Jun 30, 2025	RBF CAPITAL, LLC	0.03%	100K	884K	100K	+100.00%
Jun 30, 2025	MARSHALL WACE, LLP	0.07%	10.58K	93.53K	10.58K	+100.00%
Jun 30, 2025	ALPHABET INC.	0.1%	293.26K	2.59M	293.26K	+100.00%
Jun 30, 2025	FORESITE CAPITAL MANAGEMENT V, LLC	0.14%	406.65K	3.59M	406.65K	+100.00%
Jun 30, 2025	FORESITE CAPITAL MANAGEMENT IV, LLC	0.27%	800.4K	7.08M	800.4K	+100.00%
Jun 30, 2025	MWG MANAGEMENT LTD.	0.34%	1.01M	8.91M	-19.15M	-95.00%
Jun 30, 2025	WELLS FARGO & COMPANY/MN	0.01%	1.97K	17.41K	1.97K	+100.00%
Jun 30, 2025	IFP ADVISORS, INC	0%	3	27	3	+100.00%
Jun 30, 2025	MAI CAPITAL MANAGEMENT	0%	100	884	100	+100.00%
Jun 30, 2025		0%	250	2.21K	250	+100.00%
Jun 30, 2025	SHELL ASSET MANAGEMENT CO	0%	320	3K	320	+100.00%
Jun 30, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.01%	18K	159.12K	18K	+100.00%
Jun 30, 2025	MILLENNIUM MANAGEMENT LLC	0.35%	52.23K	461.7K	52.23K	+100.00%
Jun 30, 2025	UBS GROUP AG	0.17%	25.63K	226.61K	25.63K	+100.00%
Jun 30, 2025	DECHENG CAPITAL LLC	0.2%	595.47K	5.26M	-11.31M	-95.00%
Jun 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.45%	67.19K	593.96K	67.19K	+100.00%
Jun 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0%	353	3.12M	353	+100.00%
Jun 30, 2025	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.02%	2.97K	26.22K	2.97K	+100.00%
Jun 30, 2025	JACOBS LEVY EQUITY MANAGEMENT, INC	0.01%	39.62K	350.25K	39.62K	+100.00%
Jun 30, 2025	SUSQUEHANNA PORTFOLIO STRATEGIES, LLC	0.01%	21.7K	191.83K	21.7K	+100.00%
Jun 30, 2025	JONES FINANCIAL COMPANIES LLLP	0.01%	2K	17.88K	2K	+100.00%
Jun 30, 2025	RAYMOND JAMES FINANCIAL INC	0.05%	7.9K	69.84K	7.9K	+100.00%
Jun 30, 2025	TWO SIGMA INVESTMENTS, LP	0.07%	10.06K	88.92K	10.06K	+100.00%
Jun 30, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.08%	12.23K	108.15K	12.23K	+100.00%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.15%	22.4K	198.02K	22.4K	+100.00%
Jun 30, 2025	BARCLAYS PLC	0%	1.16K	10K	1.16K	+100.00%
Jun 30, 2025	ARCH VENTURE MANAGEMENT, LLC	0.62%	1.82M	16.11M	1.82M	+100.00%
Jun 30, 2025	WOODLINE PARTNERS LP	0.67%	98.43K	870.08K	98.43K	+100.00%
Jun 30, 2025	ACADIAN ASSET MANAGEMENT LLC	0.01%	27.37K	241K	27.37K	+100.00%
Jun 30, 2025	TAKEDA PHARMACEUTICAL CO LTD	0.01%	41.17K	363.91K	-782.15K	-95.00%
Mar 31, 2025	BBR PARTNERS, LLC	0.06%	164.04K	88.25K	0	0
Mar 31, 2025	JACOBS LEVY EQUITY MANAGEMENT, INC	0.01%	558.98K	300.73K	-826.32K	-59.65%
Mar 31, 2025	BANK OF NEW YORK MELLON CORP	0.18%	525.78K	282.87K	0	0
Mar 31, 2025	WELLS FARGO & COMPANY/MN	0.03%	96.45K	51.89K	2.13K	+2.26%
Mar 31, 2025	CANADA PENSION PLAN INVESTMENT BOARD	0.01%	588.24K	316.47K	0	0
Mar 31, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0%	244.71K	131.66K	-161.52K	-39.76%
Mar 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	0.11%	6.48M	3.49M	-431.91K	-6.25%
Mar 31, 2025	RHUMBLINE ADVISERS	0.08%	235.69K	126.79K	-45.44K	-16.16%
Mar 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0%	234.94K	126.4K	50.8K	+27.59%
Mar 31, 2025	ALLIANCEBERNSTEIN L.P.	0.07%	220.79K	118.79K	0	0
Mar 31, 2025	SQUAREPOINT OPS LLC	0.07%	198.32K	106.7K	198.32K	+100.00%
Mar 31, 2025	JPMORGAN CHASE & CO	0.07%	194.65K	104.72K	-238.61K	-55.07%
Mar 31, 2025	RAYMOND JAMES FINANCIAL INC	0.05%	158K	85K	158K	+100.00%
Mar 31, 2025	CITIGROUP INC	0.04%	117.91K	63.43K	-13.97K	-10.59%
Mar 31, 2025	UBS GROUP AG	0.04%	110.4K	59.4K	-753.89K	-87.23%
Mar 31, 2025	DECHENG CAPITAL LLC	0.2%	11.91M	6.41M	0	0
Mar 31, 2025	TD ASSET MANAGEMENT INC	0.02%	1M	540.5K	0	0
Mar 31, 2025	IKARIAN CAPITAL, LLC	0.01%	876.04K	471.31K	-400K	-31.35%
Mar 31, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.01%	513.83K	276.44K	-38.02K	-6.89%
Mar 31, 2025	INVESCO LTD.	0.01%	378.88K	203.84K	-28.33K	-6.96%
Mar 31, 2025	BARCLAYS PLC	0.06%	183.47K	99K	-74.91K	-28.99%
Mar 31, 2025	AQR CAPITAL MANAGEMENT LLC	0.06%	174.28K	93.76K	154.33K	+773.49%
Mar 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.06%	166.25K	89.44K	-87.42K	-34.46%
Mar 31, 2025	FORESITE CAPITAL MANAGEMENT IV, LLC	0.27%	16.01M	8.61M	7.68M	+92.29%
Mar 31, 2025	ALPHABET INC.	0.1%	5.87M	3.17M	0	0
Mar 31, 2025	CITADEL ADVISORS LLC	0.08%	4.51M	2.35M	752.11K	+20.03%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.49%	4.4M	2.37M	261.88K	+6.33%
Mar 31, 2025	STATE STREET CORP	0.06%	3.7M	1.99M	-46.23K	-1.23%
Mar 31, 2025	SC CHINA HOLDING LTD	0.05%	3.05M	1.46M	0	0
Mar 31, 2025	NORTHERN TRUST CORP	0.02%	1.3M	696.75K	-15.15K	-1.16%
Mar 31, 2025	JOHNSON & JOHNSON	0.01%	823.32K	442.95K	0	0
Mar 31, 2025	ACADIAN ASSET MANAGEMENT LLC	0.01%	660.9K	354K	443.61K	+204.16%
Mar 31, 2025		0.01%	641.17K	344.95K	641.17K	+100.00%
Mar 31, 2025	TWO SIGMA INVESTMENTS, LP	0.01%	387.68K	208.57K	183.18K	+89.57%
Mar 31, 2025	EXCHANGE TRADED CONCEPTS, LLC	0%	246.35K	132.54K	111.3K	+82.41%
Mar 31, 2025	BLACKROCK, INC.	0.22%	12.72M	6.84M	-544.3K	-4.10%
Mar 31, 2025	ORLAND PROPERTIES LTD	0.26%	15.09M	8.15M	0	0
Mar 31, 2025	VANGUARD GROUP INC	3.3%	9.74M	5.24M	-28.35K	-0.29%
Mar 31, 2025	VENBIO PARTNERS LLC	0.12%	7.1M	3.82M	0	0
Mar 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0.03%	1.77M	951.45K	156.35K	+9.70%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.54%	1.6M	863.32K	-41.11K	-2.50%
Mar 31, 2025	MORGAN STANLEY	0.01%	866.4K	466.13K	-347.88K	-28.65%
Mar 31, 2025	CLARIUS GROUP, LLC	0.01%	399.17K	214.75K	0	0
Mar 31, 2025	TWO SIGMA ADVISERS, LP	0.01%	391.2K	210.47K	84.8K	+27.68%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.12%	358.59K	192.92K	-268.73K	-42.84%
Mar 31, 2025	MIRAE ASSET GLOBAL ETFS HOLDINGS LTD.	0.01%	295.65K	159.06K	-12.9K	-4.18%
Mar 31, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.04%	124.7K	67.09K	55.48K	+80.14%
Mar 31, 2025	TUDOR INVESTMENT CORP ET AL	0.04%	124.32K	66.88K	0	0
Mar 31, 2025	FORESITE CAPITAL MANAGEMENT V, LLC	0.14%	8.13M	4.38M	0	0
Mar 31, 2025	MWG MANAGEMENT LTD.	0.34%	20.16M	10.85M	0	0
Mar 31, 2025	DEUTSCHE BANK AG\	0.03%	82.44K	44.52K	0	0
Mar 31, 2025	COREBRIDGE FINANCIAL, INC.	0.03%	78.73K	42.36K	-1.17K	-1.46%
Mar 31, 2025	SG AMERICAS SECURITIES, LLC	0.02%	71.88K	39K	-44.87K	-38.43%
Mar 31, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.02%	50.33K	27.08K	-2.61K	-4.92%
Mar 31, 2025	PRUDENTIAL FINANCIAL INC	0.02%	48.06K	25.86K	0	0
Mar 31, 2025	PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO	0.01%	34.31K	18.46K	-65K	-65.45%
Mar 31, 2025	VANGUARD PERSONALIZED INDEXING MANAGEMENT, LLC	0.01%	32.89K	17.69K	10.51K	+46.97%
Mar 31, 2025	AE WEALTH MANAGEMENT LLC	0.01%	25K	13.45K	0	0
Mar 31, 2025	AMERITAS INVESTMENT PARTNERS, INC.	0.01%	17.11K	9.21K	0	0
Mar 31, 2025	ALMITAS CAPITAL LLC	0.04%	2.48M	1.34M	1.43M	+136.32%
Mar 31, 2025	MIC CAPITAL MANAGEMENT UK LLP	0.03%	1.74M	936.43K	0	0
Mar 31, 2025	TAKEDA PHARMACEUTICAL CO LTD	0.01%	823.32K	442.95K	0	0
Mar 31, 2025	LEGAL & GENERAL GROUP PLC	0.01%	15.01K	8.07K	0	0
Mar 31, 2025	DIMENSIONAL FUND ADVISORS LP	0%	13.46K	7.24K	0	0
Mar 31, 2025	VISTA WEALTH MANAGEMENT GROUP, LLC	0%	13.04K	7.02K	0	0
Mar 31, 2025	ADVISORS ASSET MANAGEMENT, INC.	0%	11.62K	6.25K	11.62K	+100.00%
Mar 31, 2024	CITADEL ADVISORS LLC	0.31%	786.34K	1.75M	-2.69M	-77.39%
Mar 31, 2024	BARCLAYS PLC	0.06%	146.54K	326K	-116.53K	-44.30%
Mar 31, 2024	BBR PARTNERS, LLC	0.06%	164.04K	365.81K	0	0
Mar 31, 2024	CAXTON ASSOCIATES LP	0.07%	174.66K	389.49K	136.61K	+359.07%
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	0.07%	174.83K	389.87K	-9.42K	-5.11%
Mar 31, 2024	NEW YORK LIFE INVESTMENT MANAGEMENT LLC	0.07%	183.81K	409.89K	36.34K	+24.64%
Mar 31, 2024	JANE STREET GROUP, LLC	0.07%	187.25K	417.56K	-116.82K	-38.42%
Mar 31, 2024	UBS GROUP AG	0.08%	199.18K	444.17K	-19.66K	-8.98%
Mar 31, 2024	ORBIMED ADVISORS LLC	0.08%	199.5K	444.89K	199.5K	+100.00%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.09%	219.48K	489.44K	-1.44M	-86.78%
Mar 31, 2024	AMERICAN CENTURY COMPANIES INC	0.09%	236.67K	527.78K	91.23K	+62.72%
Mar 31, 2024	BALYASNY ASSET MANAGEMENT L.P.	0.09%	236.75K	527.96K	236.75K	+100.00%
Mar 31, 2024	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.1%	245.08K	547K	194.18K	+381.44%
Mar 31, 2024	SWISS NATIONAL BANK	0.1%	247.4K	551.7K	0	0
Mar 31, 2024	RHUMBLINE ADVISERS	0.11%	278.17K	620.31K	7.29K	+2.69%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.11%	282.58K	630.15K	-196.8K	-41.05%
Mar 31, 2024	D. E. SHAW & CO., INC.	0.15%	373.61K	833.14K	373.61K	+100.00%
Mar 31, 2024	CLARIUS GROUP, LLC	0.16%	399.17K	890.15K	0	0
Mar 31, 2024	INVESCO LTD.	0.16%	409.41K	912.98K	98.3K	+31.60%
Mar 31, 2024	RENAISSANCE TECHNOLOGIES LLC	0.17%	423.5K	944K	351K	+484.14%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.17%	425.68K	949.26K	-202.02K	-32.18%
Mar 31, 2024	TWO SIGMA INVESTMENTS, LP	0.17%	428.59K	955.76K	187.1K	+77.48%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.19%	483.45K	1.08M	19.13K	+4.12%
Mar 31, 2024	MORGAN STANLEY	0.22%	545.37K	1.22M	-2.23K	-0.41%
Mar 31, 2024	CANADA PENSION PLAN INVESTMENT BOARD	0.23%	588.24K	1.31M	0	0
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.25%	633.48K	1.41M	-27.54K	-4.17%
Mar 31, 2024	JPMORGAN CHASE & CO	0.26%	654.62K	1.46M	492.03K	+302.61%
Mar 31, 2024	BAILLIE GIFFORD & CO	0.26%	656.16K	1.46M	-34.71K	-5.02%
Mar 31, 2024	SHELL ASSET MANAGEMENT CO	0.05%	138.96K	310K	-5.03K	-3.50%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.34%	852.06K	1.9M	122.57K	+16.80%
Mar 31, 2024	INVENOMIC CAPITAL MANAGEMENT LP	0.34%	871.53K	1.94M	125.11K	+16.76%
Mar 31, 2024	TD ASSET MANAGEMENT INC	0.38%	963.84K	2.15M	47.61K	+5.20%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.51%	1.28M	2.85M	12.55K	+0.99%
Mar 31, 2024	NORTHERN TRUST CORP	0.57%	1.44M	3.22M	-33.54K	-2.27%
Mar 31, 2024	MASSACHUSETTS FINANCIAL SERVICES CO /MA/	0.61%	1.54M	3.44M	186.16K	+13.74%
Mar 31, 2024	MIC CAPITAL MANAGEMENT UK LLP	0.69%	1.74M	3.88M	0	0
Mar 31, 2024	MILLENNIUM MANAGEMENT LLC	0.8%	2.04M	4.54M	1.14M	+126.54%
Mar 31, 2024	SC CHINA HOLDING LTD	1.2%	3.05M	7.43M	0	0
Mar 31, 2024	OPALEYE MANAGEMENT INC.	1.33%	3.36M	7.48M	3.36M	+100.00%
Mar 31, 2024	STATE STREET CORP	1.47%	3.72M	8.29M	178.88K	+5.05%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	1.59%	4.02M	8.96M	79.67K	+2.02%
Mar 31, 2024	ALPHABET INC.	2.32%	5.87M	13.08M	0	0
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	2.66%	6.73M	15.01M	92.59K	+1.39%
Mar 31, 2024	WUXI APPTEC CO., LTD.	3.23%	8.18M	18.24M	0	0
Mar 31, 2024	FORESITE CAPITAL MANAGEMENT IV, LLC	3.29%	8.33M	18.56M	0	0
Mar 31, 2024	VANGUARD GROUP INC	5.29%	13.39M	29.86M	-215.6K	-1.58%
Mar 31, 2024	BLACKROCK INC.	5.49%	13.89M	30.98M	-409.59K	-2.86%
Mar 31, 2024	ORLAND PROPERTIES LTD	5.96%	15.09M	33.66M	0	0
Mar 31, 2024	FMR LLC	1.09%	2.77M	6.18M	-19.47K	-0.70%
Mar 31, 2024	NEW YORK STATE COMMON RETIREMENT FUND	0.02%	50.04K	112K	-1.25K	-2.43%
Mar 31, 2024	PRINCIPAL FINANCIAL GROUP INC	0.02%	58.25K	129.91K	-4.66K	-7.41%
Mar 31, 2024	WELLS FARGO & COMPANY/MN	0.02%	61.24K	136.57K	7.87K	+14.75%
Mar 31, 2024	SG AMERICAS SECURITIES, LLC	0.03%	68.27K	152K	-30.96K	-31.20%
Mar 31, 2024	ACADIAN ASSET MANAGEMENT LLC	0.03%	77.95K	173K	77.95K	+100.00%
Mar 31, 2024	FRANKLIN RESOURCES INC	0.03%	83.22K	185.57K	0	0
Mar 31, 2024	AMERICAN INTERNATIONAL GROUP, INC.	0.03%	85.52K	190.72K	-735	-0.85%
Mar 31, 2024	SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC	0.03%	85.75K	191.23K	85.75K	+100.00%
Mar 31, 2024	METLIFE INVESTMENT MANAGEMENT, LLC	0.04%	91.09K	203.14K	-1.01K	-1.09%
Mar 31, 2024	STATE OF WISCONSIN INVESTMENT BOARD	0.04%	92.56K	206.42K	-11.01K	-10.63%
Mar 31, 2024	PRUDENTIAL FINANCIAL INC	0.04%	95.96K	213.98K	43.9K	+84.33%
Mar 31, 2024	CORNERCAP INVESTMENT COUNSEL INC	0.04%	97.13K	216.59K	0	0
Mar 31, 2024	XTX TOPCO LTD	0.04%	110.72K	246.9K	-44.67K	-28.75%
Mar 31, 2024	LIGHTHOUSE INVESTMENT PARTNERS, LLC	0.05%	123K	274.29K	123K	+100.00%
Mar 31, 2024	CREDIT SUISSE AG/	0.05%	123.26K	274.86K	7.04K	+6.05%
Mar 31, 2024	LEGAL & GENERAL GROUP PLC	0.05%	123.53K	275.47M	2.36K	+1.95%
Mar 31, 2024	EXCHANGE TRADED CONCEPTS, LLC	0.05%	128.93K	287.51K	45.97K	+55.42%
Mar 31, 2024	VESTAL POINT CAPITAL, LP	0.05%	130K	289.9K	130K	+100.00%
Mar 31, 2024	MWG MANAGEMENT LTD.	7.97%	20.16M	44.96M	0	0
Dec 31, 2023	CREDIT SUISSE AG/	0.05%	116.22K	225.47K	-14.82K	-11.31%
Dec 31, 2023	LEGAL & GENERAL GROUP PLC	0.05%	121.17K	235.46K	0	0
Dec 31, 2023	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0.06%	140.13K	271.84K	-8.47K	-5.70%
Dec 31, 2023	SHELL ASSET MANAGEMENT CO	0.06%	143.99K	279K	-43.17K	-23.07%
Dec 31, 2023	AMERICAN CENTURY COMPANIES INC	0.06%	145.45K	282.16K	24.49K	+20.25%
Dec 31, 2023	NEW YORK LIFE INVESTMENT MANAGEMENT LLC	0.06%	147.47K	286.09K	-3.4K	-2.25%
Dec 31, 2023	XTX TOPCO LTD	0.06%	155.39K	301.46K	40.67K	+35.45%
Dec 31, 2023	JPMORGAN CHASE & CO	0.06%	162.59K	315.43K	-91.87K	-36.10%
Dec 31, 2023	BBR PARTNERS, LLC	0.07%	164.04K	318.24K	0	0
Dec 31, 2023	ALLIANCEBERNSTEIN L.P.	0.07%	184.25K	357.45K	9.59K	+5.49%
Dec 31, 2023	UBS GROUP AG	0.09%	218.84K	424.55K	23.76K	+12.18%
Dec 31, 2023	MIRAE ASSET GLOBAL INVESTMENTS CO., LTD.	0.09%	225.51K	437.48K	205.94K	+1,052.66%
Dec 31, 2023	TWO SIGMA INVESTMENTS, LP	0.1%	241.49K	468.48K	191.59K	+383.94%
Dec 31, 2023	BARCLAYS PLC	0.1%	263.07K	510K	17.83K	+7.27%
Dec 31, 2023	RHUMBLINE ADVISERS	0.11%	270.89K	525.51K	2.06K	+0.77%
Dec 31, 2023	JANE STREET GROUP, LLC	0.12%	304.07K	589.89K	289.32K	+1,961.48%
Dec 31, 2023	SQUAREPOINT OPS LLC	0.12%	304.78K	591.27K	250.83K	+464.98%
Dec 31, 2023	INVESCO LTD.	0.12%	311.11K	603.55K	18.4K	+6.29%
Dec 31, 2023	CLARIUS GROUP, LLC	0.16%	399.17K	774.39K	0	0
Dec 31, 2023	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.18%	464.33K	900.79K	0	0
Dec 31, 2023	HRT FINANCIAL LP	0.2%	496.71K	963K	496.71K	+100.00%
Dec 31, 2023	MORGAN STANLEY	0.22%	547.6K	1.06M	292.66K	+114.79%
Dec 31, 2023	CANADA PENSION PLAN INVESTMENT BOARD	0.23%	588.24K	1.14M	0	0
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.25%	627.7K	1.22M	90.08K	+16.76%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.26%	661.02K	1.28M	-544	-0.08%
Dec 31, 2023	BAILLIE GIFFORD & CO	0.27%	690.87K	1.34M	-41.77K	-5.70%
Dec 31, 2023	NUVEEN ASSET MANAGEMENT, LLC	0.29%	729.49K	1.42M	-1.77K	-0.24%
Dec 31, 2023	INVENOMIC CAPITAL MANAGEMENT LP	0.3%	746.42K	1.45M	746.42K	+100.00%
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	0.36%	899.02K	1.74M	703.5K	+359.82%
Dec 31, 2023	TD ASSET MANAGEMENT INC	0.36%	916.23K	1.78M	0	0
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.5%	1.27M	2.46M	16.15K	+1.29%
Dec 31, 2023	MASSACHUSETTS FINANCIAL SERVICES CO /MA/	0.54%	1.35M	2.63M	-8.51K	-0.62%
Dec 31, 2023	NORTHERN TRUST CORP	0.59%	1.48M	2.86M	-7.67K	-0.52%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.66%	1.66M	3.22M	932.49K	+128.07%
Dec 31, 2023	MIC CAPITAL MANAGEMENT UK LLP	0.69%	1.74M	3.38M	0	0
Dec 31, 2023	FMR LLC	1.11%	2.79M	5.41M	-58.7K	-2.06%
Dec 31, 2023	SC CHINA HOLDING LTD	1.21%	3.05M	6.4M	0	0
Dec 31, 2023	CITADEL ADVISORS LLC	1.38%	3.48M	6.75M	2.73M	+365.40%
Dec 31, 2023	STATE STREET CORP	1.41%	3.54M	6.87M	-3.27M	-48.03%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.57%	3.94M	7.64M	280.87K	+7.68%
Dec 31, 2023	ALPHABET INC.	2.33%	5.87M	11.38M	0	0
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	2.64%	6.64M	12.88M	-47.31K	-0.71%
Dec 31, 2023		3.26%	8.18M	15.87M	8.18M	+100.00%
Dec 31, 2023	FORESITE CAPITAL MANAGEMENT IV, LLC	3.31%	8.33M	16.15M	-459.81K	-5.23%
Dec 31, 2023	VANGUARD GROUP INC	5.41%	13.6M	26.39M	-3.31M	-19.55%
Dec 31, 2023	BLACKROCK INC.	5.69%	14.3M	27.75M	881.98K	+6.57%
Dec 31, 2023	SWISS NATIONAL BANK	0.1%	247.4K	479.96K	-24.3K	-8.94%
Dec 31, 2023	ORLAND PROPERTIES LTD	6.01%	15.09M	29.28M	0	0
Dec 31, 2023	MWG MANAGEMENT LTD.	8.02%	20.16M	39.11M	0	0
Dec 31, 2023	MARINER, LLC	0.05%	114.9K	222.91K	35.62K	+44.92%

Insiders

Among the LYEL insiders holding of 20.56% of the stake in company, ARCH VENTURE PARTNERS IX, LLC, 10 percent owner, holds the largest shares of 1.43M. ARCH VENTURE FUND XIII, L.P., 10 percent owner, is the second largest LYEL insider with ownership of 1.43M shares. KLAUSNER RICHARD, director, stands third with possession of 843.37K shares of that stake.

Insiders	Designation	Shares Held
ARCH VENTURE PARTNERS IX, LLC	10 percent owner	1.43M
ARCH VENTURE FUND XIII, L.P.	10 percent owner	1.43M
KLAUSNER RICHARD	director	843.37K
RAMACHANDRA SUMANT	director	200K
SEELY LYNN	President and CEO	74.27K
BRAWLEY OTIS W	director	35.64K
HILL STEPHEN J.	Chief Operating Officer	17.8K
FRIEDMAN CATHY	director	17.65K
LEE GARY K.	Chief Scientific Officer	16.94K
BULIS VERONICA SANCHEZ	VP, Corporate Controller	15.64K
NEWTON CHARLES W.	Chief Financial Officer	15.31K

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Mar 06, 2026	ARCH VENTURE FUND XIII, L.P.	PURCHASE	25.61	488.09K	12.5M	1.43M
Mar 06, 2026	ARCH VENTURE PARTNERS IX, LLC	PURCHASE	25.61	488.09K	12.5M	1.43M
Feb 11, 2026	SEELY LYNN	SALE	23.39	7.46K	174.37K	74.27K
Feb 11, 2026	LEE GARY K.	SALE	23.39	1.67K	39.08K	16.94K
Feb 11, 2026	HILL STEPHEN J.	SALE	23.39	1.24K	28.91K	17.8K
Feb 10, 2026	SEELY LYNN	SALE	23.12	438	10.13K	81.72K
Feb 10, 2026	LEE GARY K.	SALE	23.12	147	3.4K	18.61K
Feb 10, 2026	HILL STEPHEN J.	SALE	23.12	109	2.52K	19.03K
Feb 10, 2026	BULIS VERONICA SANCHEZ	SALE	23.12	254	5.87K	15.64K
Dec 30, 2025	BULIS VERONICA SANCHEZ	SALE	32.32	936	30.25K	7.14K
Dec 24, 2025	BULIS VERONICA SANCHEZ	SALE	38.67	1.14K	43.93K	8.08K
Nov 10, 2025	SEELY LYNN	SALE	16.11	412	6.64K	67.16K
Nov 10, 2025	HILL STEPHEN J.	SALE	16.12	95	1.53K	15.75K
Nov 10, 2025	LEE GARY K.	SALE	16.16	138	2.23K	15.37K
Nov 10, 2025	BULIS VERONICA SANCHEZ	SALE	16.10	239	3.85K	9.21K
Aug 21, 2025	SEELY LYNN	SALE	10.54	7.26K	76.52K	67.57K
Aug 21, 2025	HILL STEPHEN J.	SALE	10.54	1K	10.59K	15.85K
Aug 21, 2025	NEWTON CHARLES W.	SALE	10.54	1.45K	15.32K	15.31K
Aug 21, 2025	LEE GARY K.	SALE	10.54	1.45K	15.32K	15.5K
Aug 12, 2025	SEELY LYNN	SALE	10.34	406	4.2K	34.83K
Aug 12, 2025	NEWTON CHARLES W.	SALE	10.34	136	1.41K	8.76K
Aug 12, 2025	LEE GARY K.	SALE	10.34	136	1.41K	8.96K
Aug 12, 2025	HILL STEPHEN J.	SALE	10.34	94	971.77	8.85K
Aug 11, 2025	NEWTON CHARLES W.	SALE	10.53	131	1.38K	8.9K
Aug 11, 2025	HILL STEPHEN J.	SALE	10.53	91	957.87	8.94K
Aug 11, 2025	LEE GARY K.	SALE	10.53	131	1.38K	9.09K
Aug 11, 2025	SEELY LYNN	SALE	10.53	391	4.12K	35.23K
Mar 31, 2025	BRAWLEY OTIS W	PURCHASE	0.56	35.64K	19.96K	35.64K
Mar 21, 2025	RAMACHANDRA SUMANT	PURCHASE	0.58	200K	115.22K	200K
Mar 17, 2025	NEWTON CHARLES W.	PURCHASE	0.56	200K	111.62K	200K
Mar 14, 2025	KLAUSNER RICHARD	PURCHASE	0.60	158K	94.94K	843.37K
Mar 14, 2025	SEELY LYNN	PURCHASE	0.61	175K	106.19K	712.5K
Aug 15, 2023	KLAUSNER RICHARD	SALE	2.28	58.02K	132.29K	930.88K
Jun 21, 2021	FRIEDMAN CATHY	PURCHASE	17.00	17.65K	300.02K	17.65K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE976.18K2

SALES14.27K13

NET SHARES961.91K11

SHARES HELD3.22M15

% NET SHARES-70.12%-26.67%

Frequently Asked Questions