How many institutions own KRYS stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own KRYS shares is 391, representing 100.94% of the company's common stock.

Who are the major shareholders selling Krystal Biotech, Inc. stock?

UBS ASSET MANAGEMENT AMERICAS INC, in the last quarter, reduced its stake in KRYS by -59.28% restricting it's holding to 234.32 thousand shares of worth nearly $32.21M. NUVEEN, LLC also lessened -19.71% of the KRYS shares from its portfolio, reducing its holding to 188.02 thousand shares of worth $25.85M. CHARLES SCHWAB INVESTMENT MANAGEMENT INC also shunned KRYS shares holding by -1.73% last quarter which brought its holding to 246.18 thousand shares worth $33.84M.

Investors who are buying KRYS stock?

As per its latest 13F filing, FIRST TRUST ADVISORS LP increased its stake in KRYS by 571.31% in the last quarter. The institutional holder raised its holding to 222.37 thousand shares having worth more than $30.57M. NORGES BANK also added 100% more shares of KRYS to its portfolio, raising its holding to 282.71 thousand shares of worth $38.86M. GEODE CAPITAL MANAGEMENT, LLC also increased its KRYS shares holding by 1.17% which brought its holding to 619.55 thousand shares worth $85.17M.

KRYS's major insiders: who are they?

The insider with the most stakes in KRYS is Krishnan Krish S , President and CEO at the company. Additionally, KRYS stock is highly held by President, R&D Krishnan Suma and director JANNEY DANIEL among others.

Did an insider recently sell KRYS stock?

Company executives, directors, and other insiders own 11.86% percent of Krystal Biotech, Inc.'s stock. Within the last six months, there have been 10 transaction(s) in which KRYS insiders have sold stock, totaling 5.86K shares. Insiders that have sold shares include KRISHNAN SUMA, KRISHNAN KRISH S, and ROMANO KATHRYN.

Which insider recently purchased KRYS stock?

There have been 0 transaction(s) during the past 6-months in which Krystal Biotech, Inc. insiders have bought stock, totalling 0 shares

How much of KRYS does insiders own?

Around 14.48M Krystal Biotech, Inc. shares are held by insiders, which represents about 11.86% of KRYS stock.

Who is the insider with the largest stake?

KRYS President and CEO, Krishnan Krish S holds the largest portfolio of the company's shares. KRYS shares owned by Krishnan total nearly 1.44 million.

Which institution holds the most shares in KRYS?

UBS ASSET MANAGEMENT AMERICAS INC is the largest institutional owner in KRYS which holds 234.32 thousand shares worth $32.21M or 0.81% of the total KRYS shares outstanding followed by NUVEEN, LLC with ownership of 188.02 thousand shares representing 0.65% of the KRYS ownership. FIRST TRUST ADVISORS LP is the third largest stakeholder with 222.37 thousand shares or 0.77% of the ownership worth more than $30.57M.

Is Krystal Biotech, Inc. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the KRYS is concerned, it is a stock which is optionable.

Is there a short position on KRYS's shares?

Number of KRYS shares short is 3.40M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding KRYS shares are there?

As of today, 28.94M shares of KRYS are outstanding.

Is there many float in KRYS stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, KRYS has 22.98M shares in float.

KRYS short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for KRYS is 11.72.

Krystal Biotech (KRYS) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares11.74

Short Percent Of Float19.67

Shares Outstanding28.94M

Shares Float22.98M

Shares Short3.40M

Short Ratio11.72

19.67%

Short % of Float

11.74%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

11.86% Percentage of Shares held by All Insiders

100.94% Percentage of Shares held by All Institutions

114.52% Percentage of Float held by Institutions

391

Number of Institutions Holding Shares

Institutional Ownership

About 100.94% of KRYS shares are held by financial institutions. UBS ASSET MANAGEMENT AMERICAS INC is the top corporate investor, holding 234.32K shares valued at $32.21M. A 0.81% stake in Krystal Biotech, Inc. is owned by the company. NUVEEN, LLC owns 188.02K shares valued at $25.85M, which translates its holding of 0.65% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Jun 30, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.81%	234.32K	32.21M	-341.19K	-59.28%
Jun 30, 2025	NUVEEN, LLC	0.65%	188.02K	25.85M	-46.16K	-19.71%
Jun 30, 2025	FIRST TRUST ADVISORS LP	0.77%	222.37K	30.57M	189.25K	+571.31%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.85%	246.18K	33.84M	-4.33K	-1.73%
Jun 30, 2025	NORTHERN TRUST CORP	0.87%	251.41K	34.56M	-8.59K	-3.30%
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	0.9%	261.38K	35.93M	-149.48K	-36.38%
Jun 30, 2025	NORGES BANK	0.98%	282.71K	38.86M	282.71K	+100.00%
Jun 30, 2025	DIMENSIONAL FUND ADVISORS LP	1.75%	505.89K	69.54M	-28.03K	-5.25%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.14%	619.55K	85.17M	7.19K	+1.17%
Jun 30, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	2.38%	688.46K	94.64M	0	0
Jun 30, 2025	CAPITAL WORLD INVESTORS	3.26%	942.25K	129.52M	-12.22K	-1.28%
Jun 30, 2025	MORGAN STANLEY	0.81%	234.42K	32.22B	-63.78K	-21.39%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	1.83%	530.36K	72.9B	296.72K	+127.00%
Jun 30, 2025	STATE STREET CORP	4.69%	1.36M	186.31M	128.64K	+10.49%
Jun 30, 2025	AVORO CAPITAL ADVISORS LLC	9.2%	2.66M	365.64M	-71K	-2.60%
Jun 30, 2025	VANGUARD GROUP INC	9.76%	2.82M	388.03M	-2.39K	-0.08%
Jun 30, 2025	JPMORGAN CHASE & CO	0.32%	91.15K	12.53M	-9.62K	-9.55%
Jun 30, 2025	LEGAL & GENERAL GROUP PLC	0.24%	68.39K	9.4M	1.88K	+2.83%
Jun 30, 2025	RAYMOND JAMES FINANCIAL INC	0.24%	68.74K	9.45M	2.77K	+4.21%
Jun 30, 2025	RHUMBLINE ADVISERS	0.24%	70.75K	9.73M	2.03K	+2.95%
Jun 30, 2025	BARCLAYS PLC	0.32%	92.87K	12.77M	47.87K	+106.39%
Jun 30, 2025	S SQUARED TECHNOLOGY, LLC	0.38%	109.22K	15.01M	12K	+12.34%
Jun 30, 2025	CAPTION MANAGEMENT, LLC	0.42%	120K	16.5M	-101.8K	-45.90%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.41%	119.4K	16.41M	91.6K	+329.50%
Jun 30, 2025	VICTORY CAPITAL MANAGEMENT INC	0.28%	80.12K	11.01M	7.31K	+10.04%
Jun 30, 2025	C WORLDWIDE GROUP HOLDING A/S	0.3%	85.81K	11.8M	0	0
Jun 30, 2025	PUBLIC SECTOR PENSION INVESTMENT BOARD	0.3%	86.69K	11.92M	6.42K	+8.00%
Jun 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.31%	89.8K	12.34M	78.6K	+701.79%
Jun 30, 2025	WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC	0.32%	91.1K	12.52M	91.1K	+100.00%
Jun 30, 2025	ABRDN PLC	0.38%	108.52K	14.92M	71.22K	+190.93%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0.42%	121.81K	16.74M	29.25K	+31.60%
Jun 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.45%	130.54K	17.94M	65.28K	+100.02%
Jun 30, 2025	READYSTATE ASSET MANAGEMENT LP	0.51%	147.98K	20.34M	147.98K	+100.00%
Jun 30, 2025	SEGALL BRYANT & HAMILL, LLC	0.51%	148.61K	20.43M	3.28K	+2.25%
Jun 30, 2025	BRAIDWELL LP	2.52%	727.81K	100.04M	327.07K	+81.61%
Jun 30, 2025	GW&K INVESTMENT MANAGEMENT, LLC	0.1%	30.18K	4.15M	-3.93K	-11.51%
Jun 30, 2025	MAN GROUP PLC	0.11%	30.48K	4.19M	30.48K	+100.00%
Jun 30, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.12%	34.67K	4.77M	10.5K	+43.48%
Jun 30, 2025	STATE OF WISCONSIN INVESTMENT BOARD	0.12%	36.09K	4.96M	11.91K	+49.23%
Jun 30, 2025	KENNEDY CAPITAL MANAGEMENT LLC	0.13%	38.15K	5.24M	-3.37K	-8.12%
Jun 30, 2025	MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC	0.13%	38.36K	5.27M	1.93K	+5.29%
Jun 30, 2025	PALISADES INVESTMENT PARTNERS, LLC	0.14%	40.2K	5.53M	-493	-1.21%
Jun 30, 2025	CI PRIVATE WEALTH, LLC	0.14%	40.54K	5.57M	-1.59K	-3.77%
Jun 30, 2025	ALYESKA INVESTMENT GROUP, L.P.	0.19%	53.93K	7.41M	53.93K	+100.00%
Jun 30, 2025	SKANDINAVISKA ENSKILDA BANKEN AB (PUBL)	0.21%	59.98K	8.24M	0	0
Jun 30, 2025	DECHENG CAPITAL LLC	0.23%	66K	9.07M	1K	+1.54%
Jun 30, 2025	HANDELSBANKEN FONDER AB	0.23%	66.8K	9.18M	-7.5K	-10.09%
Jun 30, 2025	BLACKROCK, INC.	13.3%	3.85M	528.56M	-98.01K	-2.49%
Jun 30, 2025	FMR LLC	14.99%	4.33M	595.86M	13.93K	+0.32%
Jun 30, 2025	MIRAE ASSET GLOBAL ETFS HOLDINGS LTD.	0.05%	15.28K	2.1M	-610	-3.84%
Jun 30, 2025	DEKABANK DEUTSCHE GIROZENTRALE	0.05%	15.5K	2.15M	0	0
Jun 30, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	3.19%	922.96K	126.87M	481.2K	+108.93%
Jun 30, 2025	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0.07%	20.13K	2.77B	0	0
Jun 30, 2025	GREAT WEST LIFE ASSURANCE CO /CAN/	0.07%	20.85K	2.86M	-3.76K	-15.29%
Jun 30, 2025	EFG ASSET MANAGEMENT (NORTH AMERICA) CORP.	0.08%	22.88K	3.14M	5.51K	+31.70%
Jun 30, 2025	VERITION FUND MANAGEMENT LLC	0.09%	26.51K	3.64M	7.89K	+42.36%
Jun 30, 2025	LOS ANGELES CAPITAL MANAGEMENT LLC	0.09%	26.64K	3.66M	1.71K	+6.86%
Jun 30, 2025	ALLIANCEBERNSTEIN L.P.	0.11%	31.12K	4.28B	0	0
Jun 30, 2025	UBS GROUP AG	0.34%	97.24K	13.37M	16.12K	+19.87%
Jun 30, 2025	PRINCIPAL FINANCIAL GROUP INC	0.49%	140.88K	19.37M	14.55K	+11.51%
Jun 30, 2025	WOODLINE PARTNERS LP	0.52%	150.62K	20.7M	-71.43K	-32.17%
Jun 30, 2025	BANK OF NEW YORK MELLON CORP	0.56%	160.52K	22.06M	-8.66K	-5.12%
Jun 30, 2025	NANTAHALA CAPITAL MANAGEMENT, LLC	0.69%	200K	27.49M	200K	+100.00%
Jun 30, 2025	VIRGINIA RETIREMENT SYSTEMS ET AL	0.03%	7.8K	1.07M	0	0
Jun 30, 2025	TEALWOOD ASSET MANAGEMENT INC	0.03%	8.18K	1.13M	8.18K	+100.00%
Jun 30, 2025	TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY	0.03%	8.33K	1.15M	-681	-7.56%
Jun 30, 2025	ORBIMED ADVISORS LLC	0.03%	9.2K	1.26M	-14.3K	-60.85%
Jun 30, 2025	YOUSIF CAPITAL MANAGEMENT, LLC	0.03%	9.6K	1.32M	30	+0.31%
Jun 30, 2025	SCHRODER INVESTMENT MANAGEMENT GROUP	0.04%	10.23K	1.41M	-2.82K	-21.61%
Jun 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.04%	10.98K	1.51M	-1.1K	-9.11%
Jun 30, 2025	TORRAY INVESTMENT PARTNERS LLC	0.04%	11.57K	1.59M	11.57K	+100.00%
Jun 30, 2025	LOUISIANA STATE EMPLOYEES RETIREMENT SYSTEM	0.04%	11.9K	1.64M	0	0
Jun 30, 2025	EVOLUTIONARY TREE CAPITAL MANAGEMENT, LLC	0.04%	12.3K	1.69M	-1.05K	-7.85%
Jun 30, 2025	ILLINOIS MUNICIPAL RETIREMENT FUND	0.04%	12.31K	1.69M	-451	-3.53%
Jun 30, 2025	RHENMAN & PARTNERS ASSET MANAGEMENT AB	0.04%	12.75K	1.75M	-5K	-28.17%
Jun 30, 2025	STATE OF NEW JERSEY COMMON PENSION FUND D	0.05%	15.03K	2.07M	4.68K	+45.23%
Jun 30, 2025	HOOD RIVER CAPITAL MANAGEMENT LLC	1.84%	533.02K	73.27M	8.38K	+1.60%
Jun 30, 2025	FIERA CAPITAL CORP	0.05%	15.51K	2.13M	-134	-0.86%
Jun 30, 2025	ALPS ADVISORS INC	0.06%	17.46K	2.4M	15.54K	+809.48%
Jun 30, 2025	EDGESTREAM PARTNERS, L.P.	0.07%	19.68K	2.7M	19.68K	+100.00%
Jun 30, 2025	TD ASSET MANAGEMENT INC	0.07%	20.08K	2.76M	-20.19K	-50.13%
Jun 30, 2025	HEALTHINVEST PARTNERS AB	0.07%	20.16K	2.77M	-3.33K	-14.19%
Jun 30, 2025	SYNOVUS FINANCIAL CORP	0.07%	20.64K	2.84M	20.64K	+100.00%
Jun 30, 2025	BIONDO INVESTMENT ADVISORS, LLC	0.07%	21.24K	2.92M	21.24K	+100.00%
Jun 30, 2025		0.65%	188.02K	25.85M	-46.16K	-19.71%
Jun 30, 2025	REDMILE GROUP, LLC	2.29%	663.47K	91.2M	-74.2K	-10.06%
Jun 30, 2025	INVESCO LTD.	0.25%	70.89K	9.74M	-183.6K	-72.14%
Jun 30, 2025	MARSHALL WACE, LLP	0.39%	112.38K	15.45M	95.16K	+552.47%
Jun 30, 2025	LOGOS GLOBAL MANAGEMENT LP	0.35%	100K	13.75M	100K	+100.00%
Jun 30, 2025	TIMESSQUARE CAPITAL MANAGEMENT, LLC	0.4%	114.2K	15.7M	-27.98K	-19.68%
Mar 31, 2025	C WORLDWIDE GROUP HOLDING A/S	0.3%	85.81K	15.47M	-20K	-18.90%
Mar 31, 2025		0.81%	234.18K	42.22M	234.18K	+100.00%
Mar 31, 2025	UBS ASSET MANAGEMENT AMERICAS INC	2%	575.51K	103.76M	365.3K	+173.79%
Mar 31, 2025	HOOD RIVER CAPITAL MANAGEMENT LLC	1.82%	524.64K	94.59M	11.92K	+2.32%
Mar 31, 2025	SEGALL BRYANT & HAMILL, LLC	0.5%	145.34K	26.2M	-3.97K	-2.66%
Mar 31, 2025	TIMESSQUARE CAPITAL MANAGEMENT, LLC	0.49%	142.18K	25.64M	-16.69K	-10.50%
Mar 31, 2025	1832 ASSET MANAGEMENT L.P.	0.47%	136K	24.52M	136K	+100.00%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0.32%	92.56K	16.69M	16.76K	+22.11%
Mar 31, 2025	SQUAREPOINT OPS LLC	0.28%	82K	14.78M	72.44K	+757.82%
Mar 31, 2025	UBS GROUP AG	0.28%	81.12K	14.63M	-19.01K	-18.99%
Mar 31, 2025	PUBLIC SECTOR PENSION INVESTMENT BOARD	0.28%	80.26K	14.47M	17.25K	+27.38%
Mar 31, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.22%	64.6K	11.65M	-10.1K	-13.52%
Mar 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.43%	410.86K	74.08M	-98.6K	-19.35%
Mar 31, 2025	WOODLINE PARTNERS LP	0.77%	222.04K	40.03M	941	+0.43%
Mar 31, 2025	CAPTION MANAGEMENT, LLC	0.77%	221.8K	39.99M	143.3K	+182.55%
Mar 31, 2025	HANDELSBANKEN FONDER AB	0.26%	74.3K	13.4M	-11K	-12.90%
Mar 31, 2025	RHUMBLINE ADVISERS	0.24%	68.73K	12.39M	-409	-0.59%
Mar 31, 2025	LEGAL & GENERAL GROUP PLC	0.23%	66.51K	11.99M	-2.92K	-4.20%
Mar 31, 2025	RAYMOND JAMES FINANCIAL INC	0.23%	65.96K	11.89M	-36.1K	-35.37%
Mar 31, 2025	LORD, ABBETT & CO. LLC	0.52%	151.23K	27.27M	-64.4K	-29.87%
Mar 31, 2025	PRINCIPAL FINANCIAL GROUP INC	0.44%	126.34K	22.78M	2.88K	+2.34%
Mar 31, 2025	AVORO CAPITAL ADVISORS LLC	9.48%	2.73M	492.4M	102.18K	+3.89%
Mar 31, 2025	STATE STREET CORP	4.26%	1.23M	221.18M	-52.27K	-4.09%
Mar 31, 2025	CAPITAL WORLD INVESTORS	3.31%	954.47K	172.09M	75.27K	+8.56%
Mar 31, 2025	REDMILE GROUP, LLC	2.56%	737.68K	133M	-15.5K	-2.06%
Mar 31, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	2.39%	688.46K	124.13M	-100K	-12.68%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.13%	612.35K	110.43M	20.76K	+3.51%
Mar 31, 2025	MORGAN STANLEY	1.03%	298.21K	53.77M	41.93K	+16.36%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.87%	250.51K	45.17M	7.34K	+3.02%
Mar 31, 2025	CITIGROUP INC	0.26%	73.53K	13.26M	-26.11K	-26.20%
Mar 31, 2025	AMERIPRISE FINANCIAL INC	0.21%	60.51K	10.91M	-52.97K	-46.68%
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	0.21%	60.39K	10.89M	41.43K	+218.57%
Mar 31, 2025	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.21%	60K	10.82M	5K	+9.09%
Mar 31, 2025	EVENTIDE ASSET MANAGEMENT, LLC	0.33%	95.78K	17.27M	0	0
Mar 31, 2025	VICTORY CAPITAL MANAGEMENT INC	0.25%	72.82K	13.13M	-8.51K	-10.47%
Mar 31, 2025	BLACKROCK, INC.	13.68%	3.94M	710.95M	-90.71K	-2.25%
Mar 31, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	1.53%	441.76K	79.65M	83.38K	+23.27%
Mar 31, 2025	JPMORGAN CHASE & CO	0.35%	100.77K	18.17M	-51.06K	-33.63%
Mar 31, 2025	S SQUARED TECHNOLOGY, LLC	0.34%	97.22K	17.53M	2K	+2.10%
Mar 31, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	0.64%	185.55K	33.46M	185.55K	+100.00%
Mar 31, 2025	BANK OF NEW YORK MELLON CORP	0.59%	169.18K	30.5M	-167	-0.10%
Mar 31, 2025	FMR LLC	15%	4.32M	779.05M	6.82K	+0.16%
Mar 31, 2025	VANGUARD GROUP INC	9.8%	2.83M	509.4M	-53.17K	-1.85%
Mar 31, 2025	DIMENSIONAL FUND ADVISORS LP	1.85%	533.92K	96.27M	-54.68K	-9.29%
Mar 31, 2025	BRAIDWELL LP	1.39%	400.74K	72.25M	200.24K	+99.87%
Mar 31, 2025	NORTHERN TRUST CORP	0.9%	260K	46.88M	-2.27K	-0.86%
Mar 31, 2025	INVESCO LTD.	0.88%	254.49K	45.88M	-20.71K	-7.53%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.81%	233.64K	42.13M	-43.54K	-15.71%
Mar 31, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.23%	65.26K	11.77M	-46.83K	-41.78%
Mar 31, 2025	DECHENG CAPITAL LLC	0.23%	65K	11.72M	-11.77K	-15.33%
Mar 31, 2024	DIMENSIONAL FUND ADVISORS LP	2.11%	572.92K	101.94M	22.11K	+4.01%
Mar 31, 2024	VICTORY CAPITAL MANAGEMENT INC	0.5%	134.82K	23.99M	-38.06K	-22.01%
Mar 31, 2024	C WORLDWIDE GROUP HOLDING A/S	0.5%	135.81K	24.16M	-50K	-26.91%
Mar 31, 2024	EVENTIDE ASSET MANAGEMENT, LLC	0.5%	136.49K	24.28M	0	0
Mar 31, 2024	PICTET ASSET MANAGEMENT HOLDING SA	0.53%	142.96K	25.44M	-49.92K	-25.88%
Mar 31, 2024	ALLSPRING GLOBAL INVESTMENTS HOLDINGS, LLC	0.58%	158.43K	28.19M	99.1K	+167.05%
Mar 31, 2024	BAKER BROS. ADVISORS LP	0.63%	169.93K	30.24M	0	0
Mar 31, 2024	JPMORGAN CHASE & CO	0.64%	175.13K	31.16M	-38.39K	-17.98%
Mar 31, 2024	BRAIDWELL LP	0.65%	177.09K	31.51M	-19.11K	-9.74%
Mar 31, 2024	SCHRODER INVESTMENT MANAGEMENT GROUP	0.15%	39.48K	7.03M	-35.46K	-47.32%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.15%	41.3K	7.35M	12.05K	+41.19%
Mar 31, 2024	VESTAL POINT CAPITAL, LP	0.17%	45K	8.01M	45K	+100.00%
Mar 31, 2024	SCOUT INVESTMENTS, INC.	0.19%	50.98K	8.98M	50.98K	+100.00%
Mar 31, 2024	UBS GROUP AG	0.19%	51.03K	9.08M	20.27K	+65.89%
Mar 31, 2024	CITIGROUP INC	0.19%	52.12K	9.27M	15.55K	+42.53%
Mar 31, 2024	RAFFERTY ASSET MANAGEMENT, LLC	0.2%	53.37K	9.5M	-30.65K	-36.48%
Mar 31, 2024	VERITION FUND MANAGEMENT LLC	0.23%	61.8K	11M	-34.16K	-35.60%
Mar 31, 2024	DECHENG CAPITAL LLC	0.24%	65.77K	11.7M	0	0
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.7%	188.9K	33.61M	3.87K	+2.09%
Mar 31, 2024	NORTHERN TRUST CORP	0.76%	205.08K	36.49M	-4.12K	-1.97%
Mar 31, 2024	SKANDINAVISKA ENSKILDA BANKEN AB (PUBL)	0.8%	217.75K	38.74M	-26.31K	-10.78%
Mar 31, 2024	MORGAN STANLEY	0.81%	218.83K	38.94M	-100.89K	-31.56%
Mar 31, 2024	WOODLINE PARTNERS LP	1.01%	275.46K	49.01M	-206.52K	-42.85%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	1.6%	434.57K	77.32M	206.52K	+90.56%
Mar 31, 2024	CREDIT SUISSE AG/	1.19%	321.95K	57.28M	-152.54K	-32.15%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	1.22%	330.44K	58.79M	14.98K	+4.75%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.37%	101.56K	18.07M	93.52K	+1,162.83%
Mar 31, 2024	IKARIAN CAPITAL, LLC	0.37%	100K	17.79M	0	0
Mar 31, 2024	TIMESSQUARE CAPITAL MANAGEMENT, LLC	0.36%	97.16K	17.29M	-153.31K	-61.21%
Mar 31, 2024	CAPITAL WORLD INVESTORS	0.36%	97.15K	17.29M	97.15K	+100.00%
Mar 31, 2024	MAN GROUP PLC	0.35%	95.86K	17.06M	45.02K	+88.56%
Mar 31, 2024	JANE STREET GROUP, LLC	0.35%	93.75K	16.68M	43.13K	+85.20%
Mar 31, 2024	S SQUARED TECHNOLOGY, LLC	0.33%	90.22K	16.05M	-20K	-18.15%
Mar 31, 2024	INVESCO LTD.	0.33%	89.63K	15.95M	35.4K	+65.28%
Mar 31, 2024	SOLEUS CAPITAL MANAGEMENT, L.P.	0.31%	84.1K	14.96M	44.1K	+110.25%
Mar 31, 2024	D. E. SHAW & CO., INC.	0.3%	82.03K	14.6M	14.89K	+22.17%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.33%	89.84K	15.99M	-8.81K	-8.93%
Mar 31, 2024	FMR LLC	15.63%	4.24M	755.12M	1.86M	+77.87%
Mar 31, 2024	AVORO CAPITAL ADVISORS LLC	9.41%	2.56M	454.71M	-10K	-0.39%
Mar 31, 2024	VANGUARD GROUP INC	8.96%	2.43M	432.86M	-3K	-0.12%
Mar 31, 2024	BLACKROCK INC.	6.65%	1.81M	321.23M	-4.17K	-0.23%
Mar 31, 2024	REDMILE GROUP, LLC	5.55%	1.51M	268.36M	-224.94K	-12.98%
Mar 31, 2024	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	3.64%	988.46K	175.88M	0	0
Mar 31, 2024	STATE STREET CORP	3.48%	944.55K	168.06M	-292.95K	-23.67%
Mar 31, 2024	JENNISON ASSOCIATES LLC	2.47%	670.74K	119.34M	-53.61K	-7.40%
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	2.43%	658.62K	117.19M	231.26K	+54.11%
Mar 31, 2024	FRANKLIN RESOURCES INC	0.48%	131.47K	23.39M	104.92K	+395.23%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	1.94%	525.75K	93.56M	14.5K	+2.84%
Mar 31, 2024	HOOD RIVER CAPITAL MANAGEMENT LLC	1.83%	495.59K	88.18M	37.07K	+8.09%
Mar 31, 2024	LORD, ABBETT & CO. LLC	1.81%	492.23K	87.58M	-126.23K	-20.41%
Mar 31, 2024	BOOTHBAY FUND MANAGEMENT, LLC	0.38%	102.8K	18.29M	3.6K	+3.63%
Mar 31, 2024	ROCK SPRINGS CAPITAL MANAGEMENT LP	0.38%	103.97K	18.5M	0	0
Mar 31, 2024	HANDELSBANKEN FONDER AB	0.39%	105.2K	18.72M	-18K	-14.61%
Mar 31, 2024	DRIEHAUS CAPITAL MANAGEMENT LLC	0.41%	110.2K	19.61M	-86.19K	-43.89%
Mar 31, 2024	BALYASNY ASSET MANAGEMENT L.P.	0.46%	124.2K	22.1M	-132.4K	-51.60%
Mar 31, 2024	FIRST TURN MANAGEMENT, LLC	0.48%	130.85K	23.28M	-111.34K	-45.97%
Mar 31, 2024	TD ASSET MANAGEMENT INC	0.25%	69.16K	12.31B	28.2K	+68.84%
Mar 31, 2024	AFFINITY ASSET ADVISORS, LLC	0.1%	26.75K	4.76M	1.75K	+6.98%
Mar 31, 2024	EAM GLOBAL INVESTORS LLC	0.11%	28.84K	5.13M	28.84K	+100.00%
Mar 31, 2024	RHUMBLINE ADVISERS	0.12%	32.1K	5.71M	314	+0.99%
Mar 31, 2024	HENNION & WALSH ASSET MANAGEMENT, INC.	0.12%	33.15K	5.9M	1.76K	+5.59%
Mar 31, 2024	SEI INVESTMENTS CO	0.12%	33.75K	6.01B	18.97K	+128.30%
Mar 31, 2024	MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC	0.13%	34.19K	6.08M	-2.2K	-6.04%
Mar 31, 2024	CI PRIVATE WEALTH, LLC	0.13%	35.97K	6.4M	35.97K	+100.00%
Mar 31, 2024	SWISS NATIONAL BANK	0.13%	36.2K	6.44M	300	+0.84%
Mar 31, 2024	GW&K INVESTMENT MANAGEMENT, LLC	0.14%	37.53K	6.68M	37.53K	+100.00%
Mar 31, 2024	PRUDENTIAL FINANCIAL INC	0.14%	37.85K	6.73M	-1.71K	-4.33%
Mar 31, 2024	ABRDN PLC	0.14%	39.02K	6.94M	39.02K	+100.00%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.81%	228.05K	28.29M	43.71K	+23.71%
Dec 31, 2023		0.23%	65.77K	8.16M	65.77K	+100.00%
Dec 31, 2023	SKANDINAVISKA ENSKILDA BANKEN AB (PUBL)	0.87%	244.06K	30.28M	0	0
Dec 31, 2023	TIMESSQUARE CAPITAL MANAGEMENT, LLC	0.89%	250.47K	31.07M	127.44K	+103.58%
Dec 31, 2023	BALYASNY ASSET MANAGEMENT L.P.	0.92%	256.6K	31.83M	223.96K	+686.12%
Dec 31, 2023	NUVEEN ASSET MANAGEMENT, LLC	1.13%	315.47K	39.14M	53.23K	+20.30%
Dec 31, 2023	MORGAN STANLEY	1.14%	319.72K	39.66M	31.17K	+10.80%
Dec 31, 2023	IKARIAN CAPITAL, LLC	0.36%	100K	12.41M	100K	+100.00%
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	1.52%	427.36K	53.02M	171.16K	+66.80%
Dec 31, 2023	REDMILE GROUP, LLC	6.18%	1.73M	215.02M	-270.18K	-13.49%
Dec 31, 2023	HOOD RIVER CAPITAL MANAGEMENT LLC	1.64%	458.51K	56.88M	-1.98K	-0.43%
Dec 31, 2023	BLACKROCK INC.	6.45%	1.81M	224.49M	107.3K	+6.30%
Dec 31, 2023	FMR LLC	8.51%	2.39M	295.99M	-243.49K	-9.26%
Dec 31, 2023	VANGUARD GROUP INC	8.69%	2.44M	302.18M	35.63K	+1.48%
Dec 31, 2023	AVORO CAPITAL ADVISORS LLC	9.15%	2.57M	318.28M	0	0
Dec 31, 2023	D. E. SHAW & CO., INC.	0.24%	67.14K	8.33M	11.38K	+20.42%
Dec 31, 2023	MARSHALL WACE, LLP	0.25%	70.9K	8.8M	61.37K	+644.13%
Dec 31, 2023	SCHRODER INVESTMENT MANAGEMENT GROUP	0.27%	74.95K	9.3M	74.95K	+100.00%
Dec 31, 2023	EVERSEPT PARTNERS, LP	0.29%	80.8K	10.02M	-27.97K	-25.72%
Dec 31, 2023	RAFFERTY ASSET MANAGEMENT, LLC	0.3%	84.02K	10.42M	12.22K	+17.01%
Dec 31, 2023	C WORLDWIDE GROUP HOLDING A/S	0.66%	185.81K	23.05M	0	0
Dec 31, 2023	BRAIDWELL LP	0.7%	196.2K	24.34M	118.7K	+153.17%
Dec 31, 2023	DRIEHAUS CAPITAL MANAGEMENT LLC	0.7%	196.39K	24.36M	-2.3K	-1.16%
Dec 31, 2023	NORTHERN TRUST CORP	0.75%	209.2K	25.95M	-4.06K	-1.91%
Dec 31, 2023	JPMORGAN CHASE & CO	0.76%	213.52K	26.49M	-7.97K	-3.60%
Dec 31, 2023	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.3%	85K	10.55M	15K	+21.43%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.33%	91.19K	11.31M	27.97K	+44.24%
Dec 31, 2023	VERITION FUND MANAGEMENT LLC	0.34%	95.96K	11.9M	-31.11K	-24.48%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.35%	98.65K	12.24M	431	+0.44%
Dec 31, 2023	BOOTHBAY FUND MANAGEMENT, LLC	0.35%	99.2K	12.31M	82.1K	+480.12%
Dec 31, 2023	ORBIMED ADVISORS LLC	0.37%	103.7K	12.87M	103.7K	+100.00%
Dec 31, 2023	ROCK SPRINGS CAPITAL MANAGEMENT LP	0.37%	103.97K	12.9M	13.41K	+14.81%
Dec 31, 2023	S SQUARED TECHNOLOGY, LLC	0.39%	110.22K	13.67M	2K	+1.85%
Dec 31, 2023	HANDELSBANKEN FONDER AB	0.44%	123.2K	15.28M	10.4K	+9.22%
Dec 31, 2023	EVENTIDE ASSET MANAGEMENT, LLC	0.49%	136.49K	16.93M	136.49K	+100.00%
Dec 31, 2023	FRED ALGER MANAGEMENT, LLC	0.57%	160.34K	19.89M	-7.15K	-4.27%
Dec 31, 2023	BAKER BROS. ADVISORS LP	0.61%	169.93K	21.08M	0	0
Dec 31, 2023	VICTORY CAPITAL MANAGEMENT INC	0.62%	172.88K	21.45M	-36.61K	-17.48%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.66%	185.04K	22.96M	5.26K	+2.92%
Dec 31, 2023	CREDIT SUISSE AG/	1.69%	474.48K	58.86M	240.86K	+103.10%
Dec 31, 2023	WOODLINE PARTNERS LP	1.72%	481.98K	59.79M	160.04K	+49.71%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.82%	511.25K	63.43M	28.01K	+5.80%
Dec 31, 2023	DIMENSIONAL FUND ADVISORS LP	1.96%	550.81K	68.34M	30.17K	+5.79%
Dec 31, 2023	LORD, ABBETT & CO. LLC	2.21%	618.46K	76.73M	-52.85K	-7.87%
Dec 31, 2023	JENNISON ASSOCIATES LLC	2.58%	724.34K	89.86M	383.5K	+112.51%
Dec 31, 2023	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	3.52%	988.46K	122.63M	0	0
Dec 31, 2023	STATE STREET CORP	4.41%	1.24M	153.52M	205.67K	+19.93%

Insiders

Among the KRYS insiders holding of 11.86% of the stake in company, KRISHNAN KRISH S, President and CEO, holds the largest shares of 1.44M. KRISHNAN SUMA, President, R&D, is the second largest KRYS insider with ownership of 1.44M shares. JANNEY DANIEL, director, stands third with possession of 107.36K shares of that stake.

Insiders	Designation	Shares Held
KRISHNAN KRISH S	President and CEO	1.44M
KRISHNAN SUMA	President, R&D	1.44M
JANNEY DANIEL	director	107.36K
ROMANO KATHRYN	Chief Accounting Officer	12.6K
ROMANO KATHRYN	Chief Accounting Officer	12.56K
ORTH ANDREW C.	Chief Commercial Officer	433
GANGOLLI JULIAN S	director	0

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Jul 16, 2025	KRISHNAN SUMA	SALE	150.00	1.53K	229.35K	1.44M
Jul 16, 2025	KRISHNAN KRISH S	SALE	150.00	1.53K	229.35K	1.44M
Jul 15, 2025	KRISHNAN KRISH S	SALE	151.79	800	121.43K	1.44M
Jul 15, 2025	KRISHNAN SUMA	SALE	151.79	800	121.43K	1.44M
Jul 14, 2025	KRISHNAN SUMA	SALE	151.00	100	15.1K	1.44M
Jul 14, 2025	KRISHNAN KRISH S	SALE	151.00	100	15.1K	1.44M
Jul 10, 2025	KRISHNAN KRISH S	SALE	151.39	300	45.42K	1.46M
Jul 10, 2025	KRISHNAN SUMA	SALE	151.39	300	45.42K	1.46M
Jul 09, 2025	KRISHNAN SUMA	SALE	150.14	200	30.03K	1.46M
Jul 09, 2025	KRISHNAN KRISH S	SALE	150.14	200	30.03K	1.46M
Mar 13, 2025	KRISHNAN KRISH S	SALE	179.55	1.33K	238.98K	1.46M
Mar 13, 2025	KRISHNAN SUMA	SALE	179.55	1.33K	238.98K	1.46M
Feb 27, 2025	ROMANO KATHRYN	SALE	175.22	750	131.42K	12.6K
Dec 13, 2024	KRISHNAN SUMA	SALE	171.62	620	106.41K	1.48M
Dec 13, 2024	KRISHNAN KRISH S	SALE	171.62	620	106.41K	1.48M
Sep 12, 2024	KRISHNAN KRISH S	SALE	201.52	1.9K	381.88K	1.5M
Sep 12, 2024	KRISHNAN SUMA	SALE	201.52	1.9K	381.88K	1.5M
Jun 11, 2024	KRISHNAN SUMA	SALE	178.14	1.87K	333.31K	1.53M
Jun 11, 2024	KRISHNAN KRISH S	SALE	178.14	1.87K	333.31K	1.53M
May 20, 2024	GANGOLLI JULIAN S	SALE	165.76	1.98K	328.2K	0
Mar 11, 2024	KRISHNAN KRISH S	SALE	174.13	800	139.31K	1.55M
Mar 11, 2024	KRISHNAN SUMA	SALE	174.13	800	139.31K	1.55M
Feb 28, 2024	ROMANO KATHRYN	SALE	171.66	134	23K	12.94K
Feb 26, 2024	ROMANO KATHRYN	SALE	140.00	3.09K	432.18K	12.56K
Jan 22, 2024	ROMANO KATHRYN	SALE	130.00	2.5K	325K	12.56K
Dec 11, 2023	KRISHNAN SUMA	SALE	107.66	100	10.77K	1.57M
Dec 11, 2023	KRISHNAN KRISH S	SALE	107.66	100	10.77K	1.63M
Sep 11, 2023	KRISHNAN KRISH S	SALE	129.10	2.11K	272.4K	1.6M
Sep 11, 2023	KRISHNAN SUMA	SALE	129.10	2.11K	272.4K	1.6M
Jun 09, 2023	JANNEY DANIEL	SALE	128.53	10K	1.29M	107.36K
Jun 09, 2023	ORTH ANDREW C.	SALE	128.94	6.91K	890.49K	433
Jun 08, 2023	JANNEY DANIEL	SALE	127.86	5K	639.31K	126.3K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES5.86K10

NET SHARES-5.86K10

SHARES HELD14.48M10

% NET SHARES-100.04%0%

Frequently Asked Questions

Stock Outstanding Shares

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares11.74

Short Percent Of Float19.67

Shares Outstanding28.94M

Shares Float22.98M

Shares Short3.40M

Short Ratio11.72

19.67%

Short % of Float

11.74%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

11.86% Percentage of Shares held by All Insiders

100.94% Percentage of Shares held by All Institutions

114.52% Percentage of Float held by Institutions

391

Number of Institutions Holding Shares

Institutional Ownership

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Jun 30, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.81%	234.32K	32.21M	-341.19K	-59.28%
Jun 30, 2025	NUVEEN, LLC	0.65%	188.02K	25.85M	-46.16K	-19.71%
Jun 30, 2025	FIRST TRUST ADVISORS LP	0.77%	222.37K	30.57M	189.25K	+571.31%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.85%	246.18K	33.84M	-4.33K	-1.73%
Jun 30, 2025	NORTHERN TRUST CORP	0.87%	251.41K	34.56M	-8.59K	-3.30%
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	0.9%	261.38K	35.93M	-149.48K	-36.38%
Jun 30, 2025	NORGES BANK	0.98%	282.71K	38.86M	282.71K	+100.00%
Jun 30, 2025	DIMENSIONAL FUND ADVISORS LP	1.75%	505.89K	69.54M	-28.03K	-5.25%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.14%	619.55K	85.17M	7.19K	+1.17%
Jun 30, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	2.38%	688.46K	94.64M	0	0
Jun 30, 2025	CAPITAL WORLD INVESTORS	3.26%	942.25K	129.52M	-12.22K	-1.28%
Jun 30, 2025	MORGAN STANLEY	0.81%	234.42K	32.22B	-63.78K	-21.39%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	1.83%	530.36K	72.9B	296.72K	+127.00%
Jun 30, 2025	STATE STREET CORP	4.69%	1.36M	186.31M	128.64K	+10.49%
Jun 30, 2025	AVORO CAPITAL ADVISORS LLC	9.2%	2.66M	365.64M	-71K	-2.60%
Jun 30, 2025	VANGUARD GROUP INC	9.76%	2.82M	388.03M	-2.39K	-0.08%
Jun 30, 2025	JPMORGAN CHASE & CO	0.32%	91.15K	12.53M	-9.62K	-9.55%
Jun 30, 2025	LEGAL & GENERAL GROUP PLC	0.24%	68.39K	9.4M	1.88K	+2.83%
Jun 30, 2025	RAYMOND JAMES FINANCIAL INC	0.24%	68.74K	9.45M	2.77K	+4.21%
Jun 30, 2025	RHUMBLINE ADVISERS	0.24%	70.75K	9.73M	2.03K	+2.95%
Jun 30, 2025	BARCLAYS PLC	0.32%	92.87K	12.77M	47.87K	+106.39%
Jun 30, 2025	S SQUARED TECHNOLOGY, LLC	0.38%	109.22K	15.01M	12K	+12.34%
Jun 30, 2025	CAPTION MANAGEMENT, LLC	0.42%	120K	16.5M	-101.8K	-45.90%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.41%	119.4K	16.41M	91.6K	+329.50%
Jun 30, 2025	VICTORY CAPITAL MANAGEMENT INC	0.28%	80.12K	11.01M	7.31K	+10.04%
Jun 30, 2025	C WORLDWIDE GROUP HOLDING A/S	0.3%	85.81K	11.8M	0	0
Jun 30, 2025	PUBLIC SECTOR PENSION INVESTMENT BOARD	0.3%	86.69K	11.92M	6.42K	+8.00%
Jun 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.31%	89.8K	12.34M	78.6K	+701.79%
Jun 30, 2025	WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC	0.32%	91.1K	12.52M	91.1K	+100.00%
Jun 30, 2025	ABRDN PLC	0.38%	108.52K	14.92M	71.22K	+190.93%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0.42%	121.81K	16.74M	29.25K	+31.60%
Jun 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.45%	130.54K	17.94M	65.28K	+100.02%
Jun 30, 2025	READYSTATE ASSET MANAGEMENT LP	0.51%	147.98K	20.34M	147.98K	+100.00%
Jun 30, 2025	SEGALL BRYANT & HAMILL, LLC	0.51%	148.61K	20.43M	3.28K	+2.25%
Jun 30, 2025	BRAIDWELL LP	2.52%	727.81K	100.04M	327.07K	+81.61%
Jun 30, 2025	GW&K INVESTMENT MANAGEMENT, LLC	0.1%	30.18K	4.15M	-3.93K	-11.51%
Jun 30, 2025	MAN GROUP PLC	0.11%	30.48K	4.19M	30.48K	+100.00%
Jun 30, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.12%	34.67K	4.77M	10.5K	+43.48%
Jun 30, 2025	STATE OF WISCONSIN INVESTMENT BOARD	0.12%	36.09K	4.96M	11.91K	+49.23%
Jun 30, 2025	KENNEDY CAPITAL MANAGEMENT LLC	0.13%	38.15K	5.24M	-3.37K	-8.12%
Jun 30, 2025	MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC	0.13%	38.36K	5.27M	1.93K	+5.29%
Jun 30, 2025	PALISADES INVESTMENT PARTNERS, LLC	0.14%	40.2K	5.53M	-493	-1.21%
Jun 30, 2025	CI PRIVATE WEALTH, LLC	0.14%	40.54K	5.57M	-1.59K	-3.77%
Jun 30, 2025	ALYESKA INVESTMENT GROUP, L.P.	0.19%	53.93K	7.41M	53.93K	+100.00%
Jun 30, 2025	SKANDINAVISKA ENSKILDA BANKEN AB (PUBL)	0.21%	59.98K	8.24M	0	0
Jun 30, 2025	DECHENG CAPITAL LLC	0.23%	66K	9.07M	1K	+1.54%
Jun 30, 2025	HANDELSBANKEN FONDER AB	0.23%	66.8K	9.18M	-7.5K	-10.09%
Jun 30, 2025	BLACKROCK, INC.	13.3%	3.85M	528.56M	-98.01K	-2.49%
Jun 30, 2025	FMR LLC	14.99%	4.33M	595.86M	13.93K	+0.32%
Jun 30, 2025	MIRAE ASSET GLOBAL ETFS HOLDINGS LTD.	0.05%	15.28K	2.1M	-610	-3.84%
Jun 30, 2025	DEKABANK DEUTSCHE GIROZENTRALE	0.05%	15.5K	2.15M	0	0
Jun 30, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	3.19%	922.96K	126.87M	481.2K	+108.93%
Jun 30, 2025	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0.07%	20.13K	2.77B	0	0
Jun 30, 2025	GREAT WEST LIFE ASSURANCE CO /CAN/	0.07%	20.85K	2.86M	-3.76K	-15.29%
Jun 30, 2025	EFG ASSET MANAGEMENT (NORTH AMERICA) CORP.	0.08%	22.88K	3.14M	5.51K	+31.70%
Jun 30, 2025	VERITION FUND MANAGEMENT LLC	0.09%	26.51K	3.64M	7.89K	+42.36%
Jun 30, 2025	LOS ANGELES CAPITAL MANAGEMENT LLC	0.09%	26.64K	3.66M	1.71K	+6.86%
Jun 30, 2025	ALLIANCEBERNSTEIN L.P.	0.11%	31.12K	4.28B	0	0
Jun 30, 2025	UBS GROUP AG	0.34%	97.24K	13.37M	16.12K	+19.87%
Jun 30, 2025	PRINCIPAL FINANCIAL GROUP INC	0.49%	140.88K	19.37M	14.55K	+11.51%
Jun 30, 2025	WOODLINE PARTNERS LP	0.52%	150.62K	20.7M	-71.43K	-32.17%
Jun 30, 2025	BANK OF NEW YORK MELLON CORP	0.56%	160.52K	22.06M	-8.66K	-5.12%
Jun 30, 2025	NANTAHALA CAPITAL MANAGEMENT, LLC	0.69%	200K	27.49M	200K	+100.00%
Jun 30, 2025	VIRGINIA RETIREMENT SYSTEMS ET AL	0.03%	7.8K	1.07M	0	0
Jun 30, 2025	TEALWOOD ASSET MANAGEMENT INC	0.03%	8.18K	1.13M	8.18K	+100.00%
Jun 30, 2025	TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY	0.03%	8.33K	1.15M	-681	-7.56%
Jun 30, 2025	ORBIMED ADVISORS LLC	0.03%	9.2K	1.26M	-14.3K	-60.85%
Jun 30, 2025	YOUSIF CAPITAL MANAGEMENT, LLC	0.03%	9.6K	1.32M	30	+0.31%
Jun 30, 2025	SCHRODER INVESTMENT MANAGEMENT GROUP	0.04%	10.23K	1.41M	-2.82K	-21.61%
Jun 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.04%	10.98K	1.51M	-1.1K	-9.11%
Jun 30, 2025	TORRAY INVESTMENT PARTNERS LLC	0.04%	11.57K	1.59M	11.57K	+100.00%
Jun 30, 2025	LOUISIANA STATE EMPLOYEES RETIREMENT SYSTEM	0.04%	11.9K	1.64M	0	0
Jun 30, 2025	EVOLUTIONARY TREE CAPITAL MANAGEMENT, LLC	0.04%	12.3K	1.69M	-1.05K	-7.85%
Jun 30, 2025	ILLINOIS MUNICIPAL RETIREMENT FUND	0.04%	12.31K	1.69M	-451	-3.53%
Jun 30, 2025	RHENMAN & PARTNERS ASSET MANAGEMENT AB	0.04%	12.75K	1.75M	-5K	-28.17%
Jun 30, 2025	STATE OF NEW JERSEY COMMON PENSION FUND D	0.05%	15.03K	2.07M	4.68K	+45.23%
Jun 30, 2025	HOOD RIVER CAPITAL MANAGEMENT LLC	1.84%	533.02K	73.27M	8.38K	+1.60%
Jun 30, 2025	FIERA CAPITAL CORP	0.05%	15.51K	2.13M	-134	-0.86%
Jun 30, 2025	ALPS ADVISORS INC	0.06%	17.46K	2.4M	15.54K	+809.48%
Jun 30, 2025	EDGESTREAM PARTNERS, L.P.	0.07%	19.68K	2.7M	19.68K	+100.00%
Jun 30, 2025	TD ASSET MANAGEMENT INC	0.07%	20.08K	2.76M	-20.19K	-50.13%
Jun 30, 2025	HEALTHINVEST PARTNERS AB	0.07%	20.16K	2.77M	-3.33K	-14.19%
Jun 30, 2025	SYNOVUS FINANCIAL CORP	0.07%	20.64K	2.84M	20.64K	+100.00%
Jun 30, 2025	BIONDO INVESTMENT ADVISORS, LLC	0.07%	21.24K	2.92M	21.24K	+100.00%
Jun 30, 2025		0.65%	188.02K	25.85M	-46.16K	-19.71%
Jun 30, 2025	REDMILE GROUP, LLC	2.29%	663.47K	91.2M	-74.2K	-10.06%
Jun 30, 2025	INVESCO LTD.	0.25%	70.89K	9.74M	-183.6K	-72.14%
Jun 30, 2025	MARSHALL WACE, LLP	0.39%	112.38K	15.45M	95.16K	+552.47%
Jun 30, 2025	LOGOS GLOBAL MANAGEMENT LP	0.35%	100K	13.75M	100K	+100.00%
Jun 30, 2025	TIMESSQUARE CAPITAL MANAGEMENT, LLC	0.4%	114.2K	15.7M	-27.98K	-19.68%
Mar 31, 2025	C WORLDWIDE GROUP HOLDING A/S	0.3%	85.81K	15.47M	-20K	-18.90%
Mar 31, 2025		0.81%	234.18K	42.22M	234.18K	+100.00%
Mar 31, 2025	UBS ASSET MANAGEMENT AMERICAS INC	2%	575.51K	103.76M	365.3K	+173.79%
Mar 31, 2025	HOOD RIVER CAPITAL MANAGEMENT LLC	1.82%	524.64K	94.59M	11.92K	+2.32%
Mar 31, 2025	SEGALL BRYANT & HAMILL, LLC	0.5%	145.34K	26.2M	-3.97K	-2.66%
Mar 31, 2025	TIMESSQUARE CAPITAL MANAGEMENT, LLC	0.49%	142.18K	25.64M	-16.69K	-10.50%
Mar 31, 2025	1832 ASSET MANAGEMENT L.P.	0.47%	136K	24.52M	136K	+100.00%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0.32%	92.56K	16.69M	16.76K	+22.11%
Mar 31, 2025	SQUAREPOINT OPS LLC	0.28%	82K	14.78M	72.44K	+757.82%
Mar 31, 2025	UBS GROUP AG	0.28%	81.12K	14.63M	-19.01K	-18.99%
Mar 31, 2025	PUBLIC SECTOR PENSION INVESTMENT BOARD	0.28%	80.26K	14.47M	17.25K	+27.38%
Mar 31, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.22%	64.6K	11.65M	-10.1K	-13.52%
Mar 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.43%	410.86K	74.08M	-98.6K	-19.35%
Mar 31, 2025	WOODLINE PARTNERS LP	0.77%	222.04K	40.03M	941	+0.43%
Mar 31, 2025	CAPTION MANAGEMENT, LLC	0.77%	221.8K	39.99M	143.3K	+182.55%
Mar 31, 2025	HANDELSBANKEN FONDER AB	0.26%	74.3K	13.4M	-11K	-12.90%
Mar 31, 2025	RHUMBLINE ADVISERS	0.24%	68.73K	12.39M	-409	-0.59%
Mar 31, 2025	LEGAL & GENERAL GROUP PLC	0.23%	66.51K	11.99M	-2.92K	-4.20%
Mar 31, 2025	RAYMOND JAMES FINANCIAL INC	0.23%	65.96K	11.89M	-36.1K	-35.37%
Mar 31, 2025	LORD, ABBETT & CO. LLC	0.52%	151.23K	27.27M	-64.4K	-29.87%
Mar 31, 2025	PRINCIPAL FINANCIAL GROUP INC	0.44%	126.34K	22.78M	2.88K	+2.34%
Mar 31, 2025	AVORO CAPITAL ADVISORS LLC	9.48%	2.73M	492.4M	102.18K	+3.89%
Mar 31, 2025	STATE STREET CORP	4.26%	1.23M	221.18M	-52.27K	-4.09%
Mar 31, 2025	CAPITAL WORLD INVESTORS	3.31%	954.47K	172.09M	75.27K	+8.56%
Mar 31, 2025	REDMILE GROUP, LLC	2.56%	737.68K	133M	-15.5K	-2.06%
Mar 31, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	2.39%	688.46K	124.13M	-100K	-12.68%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.13%	612.35K	110.43M	20.76K	+3.51%
Mar 31, 2025	MORGAN STANLEY	1.03%	298.21K	53.77M	41.93K	+16.36%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.87%	250.51K	45.17M	7.34K	+3.02%
Mar 31, 2025	CITIGROUP INC	0.26%	73.53K	13.26M	-26.11K	-26.20%
Mar 31, 2025	AMERIPRISE FINANCIAL INC	0.21%	60.51K	10.91M	-52.97K	-46.68%
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	0.21%	60.39K	10.89M	41.43K	+218.57%
Mar 31, 2025	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.21%	60K	10.82M	5K	+9.09%
Mar 31, 2025	EVENTIDE ASSET MANAGEMENT, LLC	0.33%	95.78K	17.27M	0	0
Mar 31, 2025	VICTORY CAPITAL MANAGEMENT INC	0.25%	72.82K	13.13M	-8.51K	-10.47%
Mar 31, 2025	BLACKROCK, INC.	13.68%	3.94M	710.95M	-90.71K	-2.25%
Mar 31, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	1.53%	441.76K	79.65M	83.38K	+23.27%
Mar 31, 2025	JPMORGAN CHASE & CO	0.35%	100.77K	18.17M	-51.06K	-33.63%
Mar 31, 2025	S SQUARED TECHNOLOGY, LLC	0.34%	97.22K	17.53M	2K	+2.10%
Mar 31, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	0.64%	185.55K	33.46M	185.55K	+100.00%
Mar 31, 2025	BANK OF NEW YORK MELLON CORP	0.59%	169.18K	30.5M	-167	-0.10%
Mar 31, 2025	FMR LLC	15%	4.32M	779.05M	6.82K	+0.16%
Mar 31, 2025	VANGUARD GROUP INC	9.8%	2.83M	509.4M	-53.17K	-1.85%
Mar 31, 2025	DIMENSIONAL FUND ADVISORS LP	1.85%	533.92K	96.27M	-54.68K	-9.29%
Mar 31, 2025	BRAIDWELL LP	1.39%	400.74K	72.25M	200.24K	+99.87%
Mar 31, 2025	NORTHERN TRUST CORP	0.9%	260K	46.88M	-2.27K	-0.86%
Mar 31, 2025	INVESCO LTD.	0.88%	254.49K	45.88M	-20.71K	-7.53%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.81%	233.64K	42.13M	-43.54K	-15.71%
Mar 31, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.23%	65.26K	11.77M	-46.83K	-41.78%
Mar 31, 2025	DECHENG CAPITAL LLC	0.23%	65K	11.72M	-11.77K	-15.33%
Mar 31, 2024	DIMENSIONAL FUND ADVISORS LP	2.11%	572.92K	101.94M	22.11K	+4.01%
Mar 31, 2024	VICTORY CAPITAL MANAGEMENT INC	0.5%	134.82K	23.99M	-38.06K	-22.01%
Mar 31, 2024	C WORLDWIDE GROUP HOLDING A/S	0.5%	135.81K	24.16M	-50K	-26.91%
Mar 31, 2024	EVENTIDE ASSET MANAGEMENT, LLC	0.5%	136.49K	24.28M	0	0
Mar 31, 2024	PICTET ASSET MANAGEMENT HOLDING SA	0.53%	142.96K	25.44M	-49.92K	-25.88%
Mar 31, 2024	ALLSPRING GLOBAL INVESTMENTS HOLDINGS, LLC	0.58%	158.43K	28.19M	99.1K	+167.05%
Mar 31, 2024	BAKER BROS. ADVISORS LP	0.63%	169.93K	30.24M	0	0
Mar 31, 2024	JPMORGAN CHASE & CO	0.64%	175.13K	31.16M	-38.39K	-17.98%
Mar 31, 2024	BRAIDWELL LP	0.65%	177.09K	31.51M	-19.11K	-9.74%
Mar 31, 2024	SCHRODER INVESTMENT MANAGEMENT GROUP	0.15%	39.48K	7.03M	-35.46K	-47.32%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.15%	41.3K	7.35M	12.05K	+41.19%
Mar 31, 2024	VESTAL POINT CAPITAL, LP	0.17%	45K	8.01M	45K	+100.00%
Mar 31, 2024	SCOUT INVESTMENTS, INC.	0.19%	50.98K	8.98M	50.98K	+100.00%
Mar 31, 2024	UBS GROUP AG	0.19%	51.03K	9.08M	20.27K	+65.89%
Mar 31, 2024	CITIGROUP INC	0.19%	52.12K	9.27M	15.55K	+42.53%
Mar 31, 2024	RAFFERTY ASSET MANAGEMENT, LLC	0.2%	53.37K	9.5M	-30.65K	-36.48%
Mar 31, 2024	VERITION FUND MANAGEMENT LLC	0.23%	61.8K	11M	-34.16K	-35.60%
Mar 31, 2024	DECHENG CAPITAL LLC	0.24%	65.77K	11.7M	0	0
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.7%	188.9K	33.61M	3.87K	+2.09%
Mar 31, 2024	NORTHERN TRUST CORP	0.76%	205.08K	36.49M	-4.12K	-1.97%
Mar 31, 2024	SKANDINAVISKA ENSKILDA BANKEN AB (PUBL)	0.8%	217.75K	38.74M	-26.31K	-10.78%
Mar 31, 2024	MORGAN STANLEY	0.81%	218.83K	38.94M	-100.89K	-31.56%
Mar 31, 2024	WOODLINE PARTNERS LP	1.01%	275.46K	49.01M	-206.52K	-42.85%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	1.6%	434.57K	77.32M	206.52K	+90.56%
Mar 31, 2024	CREDIT SUISSE AG/	1.19%	321.95K	57.28M	-152.54K	-32.15%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	1.22%	330.44K	58.79M	14.98K	+4.75%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.37%	101.56K	18.07M	93.52K	+1,162.83%
Mar 31, 2024	IKARIAN CAPITAL, LLC	0.37%	100K	17.79M	0	0
Mar 31, 2024	TIMESSQUARE CAPITAL MANAGEMENT, LLC	0.36%	97.16K	17.29M	-153.31K	-61.21%
Mar 31, 2024	CAPITAL WORLD INVESTORS	0.36%	97.15K	17.29M	97.15K	+100.00%
Mar 31, 2024	MAN GROUP PLC	0.35%	95.86K	17.06M	45.02K	+88.56%
Mar 31, 2024	JANE STREET GROUP, LLC	0.35%	93.75K	16.68M	43.13K	+85.20%
Mar 31, 2024	S SQUARED TECHNOLOGY, LLC	0.33%	90.22K	16.05M	-20K	-18.15%
Mar 31, 2024	INVESCO LTD.	0.33%	89.63K	15.95M	35.4K	+65.28%
Mar 31, 2024	SOLEUS CAPITAL MANAGEMENT, L.P.	0.31%	84.1K	14.96M	44.1K	+110.25%
Mar 31, 2024	D. E. SHAW & CO., INC.	0.3%	82.03K	14.6M	14.89K	+22.17%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.33%	89.84K	15.99M	-8.81K	-8.93%
Mar 31, 2024	FMR LLC	15.63%	4.24M	755.12M	1.86M	+77.87%
Mar 31, 2024	AVORO CAPITAL ADVISORS LLC	9.41%	2.56M	454.71M	-10K	-0.39%
Mar 31, 2024	VANGUARD GROUP INC	8.96%	2.43M	432.86M	-3K	-0.12%
Mar 31, 2024	BLACKROCK INC.	6.65%	1.81M	321.23M	-4.17K	-0.23%
Mar 31, 2024	REDMILE GROUP, LLC	5.55%	1.51M	268.36M	-224.94K	-12.98%
Mar 31, 2024	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	3.64%	988.46K	175.88M	0	0
Mar 31, 2024	STATE STREET CORP	3.48%	944.55K	168.06M	-292.95K	-23.67%
Mar 31, 2024	JENNISON ASSOCIATES LLC	2.47%	670.74K	119.34M	-53.61K	-7.40%
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	2.43%	658.62K	117.19M	231.26K	+54.11%
Mar 31, 2024	FRANKLIN RESOURCES INC	0.48%	131.47K	23.39M	104.92K	+395.23%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	1.94%	525.75K	93.56M	14.5K	+2.84%
Mar 31, 2024	HOOD RIVER CAPITAL MANAGEMENT LLC	1.83%	495.59K	88.18M	37.07K	+8.09%
Mar 31, 2024	LORD, ABBETT & CO. LLC	1.81%	492.23K	87.58M	-126.23K	-20.41%
Mar 31, 2024	BOOTHBAY FUND MANAGEMENT, LLC	0.38%	102.8K	18.29M	3.6K	+3.63%
Mar 31, 2024	ROCK SPRINGS CAPITAL MANAGEMENT LP	0.38%	103.97K	18.5M	0	0
Mar 31, 2024	HANDELSBANKEN FONDER AB	0.39%	105.2K	18.72M	-18K	-14.61%
Mar 31, 2024	DRIEHAUS CAPITAL MANAGEMENT LLC	0.41%	110.2K	19.61M	-86.19K	-43.89%
Mar 31, 2024	BALYASNY ASSET MANAGEMENT L.P.	0.46%	124.2K	22.1M	-132.4K	-51.60%
Mar 31, 2024	FIRST TURN MANAGEMENT, LLC	0.48%	130.85K	23.28M	-111.34K	-45.97%
Mar 31, 2024	TD ASSET MANAGEMENT INC	0.25%	69.16K	12.31B	28.2K	+68.84%
Mar 31, 2024	AFFINITY ASSET ADVISORS, LLC	0.1%	26.75K	4.76M	1.75K	+6.98%
Mar 31, 2024	EAM GLOBAL INVESTORS LLC	0.11%	28.84K	5.13M	28.84K	+100.00%
Mar 31, 2024	RHUMBLINE ADVISERS	0.12%	32.1K	5.71M	314	+0.99%
Mar 31, 2024	HENNION & WALSH ASSET MANAGEMENT, INC.	0.12%	33.15K	5.9M	1.76K	+5.59%
Mar 31, 2024	SEI INVESTMENTS CO	0.12%	33.75K	6.01B	18.97K	+128.30%
Mar 31, 2024	MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC	0.13%	34.19K	6.08M	-2.2K	-6.04%
Mar 31, 2024	CI PRIVATE WEALTH, LLC	0.13%	35.97K	6.4M	35.97K	+100.00%
Mar 31, 2024	SWISS NATIONAL BANK	0.13%	36.2K	6.44M	300	+0.84%
Mar 31, 2024	GW&K INVESTMENT MANAGEMENT, LLC	0.14%	37.53K	6.68M	37.53K	+100.00%
Mar 31, 2024	PRUDENTIAL FINANCIAL INC	0.14%	37.85K	6.73M	-1.71K	-4.33%
Mar 31, 2024	ABRDN PLC	0.14%	39.02K	6.94M	39.02K	+100.00%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.81%	228.05K	28.29M	43.71K	+23.71%
Dec 31, 2023		0.23%	65.77K	8.16M	65.77K	+100.00%
Dec 31, 2023	SKANDINAVISKA ENSKILDA BANKEN AB (PUBL)	0.87%	244.06K	30.28M	0	0
Dec 31, 2023	TIMESSQUARE CAPITAL MANAGEMENT, LLC	0.89%	250.47K	31.07M	127.44K	+103.58%
Dec 31, 2023	BALYASNY ASSET MANAGEMENT L.P.	0.92%	256.6K	31.83M	223.96K	+686.12%
Dec 31, 2023	NUVEEN ASSET MANAGEMENT, LLC	1.13%	315.47K	39.14M	53.23K	+20.30%
Dec 31, 2023	MORGAN STANLEY	1.14%	319.72K	39.66M	31.17K	+10.80%
Dec 31, 2023	IKARIAN CAPITAL, LLC	0.36%	100K	12.41M	100K	+100.00%
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	1.52%	427.36K	53.02M	171.16K	+66.80%
Dec 31, 2023	REDMILE GROUP, LLC	6.18%	1.73M	215.02M	-270.18K	-13.49%
Dec 31, 2023	HOOD RIVER CAPITAL MANAGEMENT LLC	1.64%	458.51K	56.88M	-1.98K	-0.43%
Dec 31, 2023	BLACKROCK INC.	6.45%	1.81M	224.49M	107.3K	+6.30%
Dec 31, 2023	FMR LLC	8.51%	2.39M	295.99M	-243.49K	-9.26%
Dec 31, 2023	VANGUARD GROUP INC	8.69%	2.44M	302.18M	35.63K	+1.48%
Dec 31, 2023	AVORO CAPITAL ADVISORS LLC	9.15%	2.57M	318.28M	0	0
Dec 31, 2023	D. E. SHAW & CO., INC.	0.24%	67.14K	8.33M	11.38K	+20.42%
Dec 31, 2023	MARSHALL WACE, LLP	0.25%	70.9K	8.8M	61.37K	+644.13%
Dec 31, 2023	SCHRODER INVESTMENT MANAGEMENT GROUP	0.27%	74.95K	9.3M	74.95K	+100.00%
Dec 31, 2023	EVERSEPT PARTNERS, LP	0.29%	80.8K	10.02M	-27.97K	-25.72%
Dec 31, 2023	RAFFERTY ASSET MANAGEMENT, LLC	0.3%	84.02K	10.42M	12.22K	+17.01%
Dec 31, 2023	C WORLDWIDE GROUP HOLDING A/S	0.66%	185.81K	23.05M	0	0
Dec 31, 2023	BRAIDWELL LP	0.7%	196.2K	24.34M	118.7K	+153.17%
Dec 31, 2023	DRIEHAUS CAPITAL MANAGEMENT LLC	0.7%	196.39K	24.36M	-2.3K	-1.16%
Dec 31, 2023	NORTHERN TRUST CORP	0.75%	209.2K	25.95M	-4.06K	-1.91%
Dec 31, 2023	JPMORGAN CHASE & CO	0.76%	213.52K	26.49M	-7.97K	-3.60%
Dec 31, 2023	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.3%	85K	10.55M	15K	+21.43%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.33%	91.19K	11.31M	27.97K	+44.24%
Dec 31, 2023	VERITION FUND MANAGEMENT LLC	0.34%	95.96K	11.9M	-31.11K	-24.48%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.35%	98.65K	12.24M	431	+0.44%
Dec 31, 2023	BOOTHBAY FUND MANAGEMENT, LLC	0.35%	99.2K	12.31M	82.1K	+480.12%
Dec 31, 2023	ORBIMED ADVISORS LLC	0.37%	103.7K	12.87M	103.7K	+100.00%
Dec 31, 2023	ROCK SPRINGS CAPITAL MANAGEMENT LP	0.37%	103.97K	12.9M	13.41K	+14.81%
Dec 31, 2023	S SQUARED TECHNOLOGY, LLC	0.39%	110.22K	13.67M	2K	+1.85%
Dec 31, 2023	HANDELSBANKEN FONDER AB	0.44%	123.2K	15.28M	10.4K	+9.22%
Dec 31, 2023	EVENTIDE ASSET MANAGEMENT, LLC	0.49%	136.49K	16.93M	136.49K	+100.00%
Dec 31, 2023	FRED ALGER MANAGEMENT, LLC	0.57%	160.34K	19.89M	-7.15K	-4.27%
Dec 31, 2023	BAKER BROS. ADVISORS LP	0.61%	169.93K	21.08M	0	0
Dec 31, 2023	VICTORY CAPITAL MANAGEMENT INC	0.62%	172.88K	21.45M	-36.61K	-17.48%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.66%	185.04K	22.96M	5.26K	+2.92%
Dec 31, 2023	CREDIT SUISSE AG/	1.69%	474.48K	58.86M	240.86K	+103.10%
Dec 31, 2023	WOODLINE PARTNERS LP	1.72%	481.98K	59.79M	160.04K	+49.71%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.82%	511.25K	63.43M	28.01K	+5.80%
Dec 31, 2023	DIMENSIONAL FUND ADVISORS LP	1.96%	550.81K	68.34M	30.17K	+5.79%
Dec 31, 2023	LORD, ABBETT & CO. LLC	2.21%	618.46K	76.73M	-52.85K	-7.87%
Dec 31, 2023	JENNISON ASSOCIATES LLC	2.58%	724.34K	89.86M	383.5K	+112.51%
Dec 31, 2023	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	3.52%	988.46K	122.63M	0	0
Dec 31, 2023	STATE STREET CORP	4.41%	1.24M	153.52M	205.67K	+19.93%

Insiders

Insiders	Designation	Shares Held
KRISHNAN KRISH S	President and CEO	1.44M
KRISHNAN SUMA	President, R&D	1.44M
JANNEY DANIEL	director	107.36K
ROMANO KATHRYN	Chief Accounting Officer	12.6K
ROMANO KATHRYN	Chief Accounting Officer	12.56K
ORTH ANDREW C.	Chief Commercial Officer	433
GANGOLLI JULIAN S	director	0

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Jul 16, 2025	KRISHNAN SUMA	SALE	150.00	1.53K	229.35K	1.44M
Jul 16, 2025	KRISHNAN KRISH S	SALE	150.00	1.53K	229.35K	1.44M
Jul 15, 2025	KRISHNAN KRISH S	SALE	151.79	800	121.43K	1.44M
Jul 15, 2025	KRISHNAN SUMA	SALE	151.79	800	121.43K	1.44M
Jul 14, 2025	KRISHNAN SUMA	SALE	151.00	100	15.1K	1.44M
Jul 14, 2025	KRISHNAN KRISH S	SALE	151.00	100	15.1K	1.44M
Jul 10, 2025	KRISHNAN KRISH S	SALE	151.39	300	45.42K	1.46M
Jul 10, 2025	KRISHNAN SUMA	SALE	151.39	300	45.42K	1.46M
Jul 09, 2025	KRISHNAN SUMA	SALE	150.14	200	30.03K	1.46M
Jul 09, 2025	KRISHNAN KRISH S	SALE	150.14	200	30.03K	1.46M
Mar 13, 2025	KRISHNAN KRISH S	SALE	179.55	1.33K	238.98K	1.46M
Mar 13, 2025	KRISHNAN SUMA	SALE	179.55	1.33K	238.98K	1.46M
Feb 27, 2025	ROMANO KATHRYN	SALE	175.22	750	131.42K	12.6K
Dec 13, 2024	KRISHNAN SUMA	SALE	171.62	620	106.41K	1.48M
Dec 13, 2024	KRISHNAN KRISH S	SALE	171.62	620	106.41K	1.48M
Sep 12, 2024	KRISHNAN KRISH S	SALE	201.52	1.9K	381.88K	1.5M
Sep 12, 2024	KRISHNAN SUMA	SALE	201.52	1.9K	381.88K	1.5M
Jun 11, 2024	KRISHNAN SUMA	SALE	178.14	1.87K	333.31K	1.53M
Jun 11, 2024	KRISHNAN KRISH S	SALE	178.14	1.87K	333.31K	1.53M
May 20, 2024	GANGOLLI JULIAN S	SALE	165.76	1.98K	328.2K	0
Mar 11, 2024	KRISHNAN KRISH S	SALE	174.13	800	139.31K	1.55M
Mar 11, 2024	KRISHNAN SUMA	SALE	174.13	800	139.31K	1.55M
Feb 28, 2024	ROMANO KATHRYN	SALE	171.66	134	23K	12.94K
Feb 26, 2024	ROMANO KATHRYN	SALE	140.00	3.09K	432.18K	12.56K
Jan 22, 2024	ROMANO KATHRYN	SALE	130.00	2.5K	325K	12.56K
Dec 11, 2023	KRISHNAN SUMA	SALE	107.66	100	10.77K	1.57M
Dec 11, 2023	KRISHNAN KRISH S	SALE	107.66	100	10.77K	1.63M
Sep 11, 2023	KRISHNAN KRISH S	SALE	129.10	2.11K	272.4K	1.6M
Sep 11, 2023	KRISHNAN SUMA	SALE	129.10	2.11K	272.4K	1.6M
Jun 09, 2023	JANNEY DANIEL	SALE	128.53	10K	1.29M	107.36K
Jun 09, 2023	ORTH ANDREW C.	SALE	128.94	6.91K	890.49K	433
Jun 08, 2023	JANNEY DANIEL	SALE	127.86	5K	639.31K	126.3K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES5.86K10

NET SHARES-5.86K10

SHARES HELD14.48M10

% NET SHARES-100.04%0%

KRYS Stock Ownership Breakdown

Krystal Biotech

Stock Outstanding Shares

Market Insider

Institutional Ownership

Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions

Stock Outstanding Shares

Market Insider

Institutional Ownership

Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions