How many institutions own KALA stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own KALA shares is 34, representing 51.86% of the company's common stock.

Who are the major shareholders selling KALA BIO, Inc. stock?

GEODE CAPITAL MANAGEMENT, LLC, in the last quarter, reduced its stake in KALA by -9.94% restricting it's holding to 61.16 thousand shares of worth nearly $34.01K. VANGUARD GROUP INC also lessened -56.83% of the KALA shares from its portfolio, reducing its holding to 91.01 thousand shares of worth $50.60K. TOWER RESEARCH CAPITAL LLC (TRC) also shunned KALA shares holding by -100% last quarter which brought its holding to 0 shares worth -.

Investors who are buying KALA stock?

As per its latest 13F filing, CITIGROUP INC increased its stake in KALA by 1,508.32% in the last quarter. The institutional holder raised its holding to 11.6 thousand shares having worth more than $6.45K. UBS GROUP AG also added 191.83% more shares of KALA to its portfolio, raising its holding to 23.91 thousand shares of worth $13.29K. TWO SIGMA INVESTMENTS, LP also increased its KALA shares holding by 100% which brought its holding to 26.9 thousand shares worth $14.95K.

KALA's major insiders: who are they?

The insider with the most stakes in KALA is Shah Rajeev M. , at the company. Additionally, KALA stock is highly held by 10 percent owner RA CAPITAL MANAGEMENT, L.P. and RA CAPITAL MANAGEMENT, LLC among others.

Did an insider recently sell KALA stock?

Company executives, directors, and other insiders own 1.75% percent of KALA BIO, Inc.'s stock. Within the last six months, there have been 8 transaction(s) in which KALA insiders have sold stock, totaling 375.43K shares. Insiders that have sold shares include REUMUTH MARY, IWICKI MARK T, and BRAZZELL ROMULUS K.

Which insider recently purchased KALA stock?

There have been 0 transaction(s) during the past 6-months in which KALA BIO, Inc. insiders have bought stock, totalling 0 shares

How much of KALA does insiders own?

Around 419.56K KALA BIO, Inc. shares are held by insiders, which represents about 1.75% of KALA stock.

Who is the insider with the largest stake?

KALA , Shah Rajeev M. holds the largest portfolio of the company's shares. KALA shares owned by Shah total nearly 7.04 million.

Which institution holds the most shares in KALA?

CITIGROUP INC is the largest institutional owner in KALA which holds 11.6 thousand shares worth $6.45K or 0.16% of the total KALA shares outstanding followed by BLACKROCK, INC. with ownership of 21.41 thousand shares representing 0.3% of the KALA ownership. UBS GROUP AG is the third largest stakeholder with 23.91 thousand shares or 0.34% of the ownership worth more than $13.29K.

Is KALA BIO, Inc. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the KALA is concerned, it is a stock which is not optionable.

Is there a short position on KALA's shares?

Number of KALA shares short is 348.23K. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding KALA shares are there?

As of today, 7.02M shares of KALA are outstanding.

Is there many float in KALA stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, KALA has 4.25M shares in float.

KALA short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for KALA is 1.71.

KALA BIO (KALA) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableNo

Short Percent Of Outstanding Shares5.4

Short Percent Of Float6.87

Shares Outstanding7.02M

Shares Float4.25M

Shares Short348.23K

Short Ratio1.71

6.87%

Short % of Float

5.4%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

1.75% Percentage of Shares held by All Insiders

51.86% Percentage of Shares held by All Institutions

52.79% Percentage of Float held by Institutions

Number of Institutions Holding Shares

Institutional Ownership

About 51.86% of KALA shares are held by financial institutions. CITIGROUP INC is the top corporate investor, holding 11.6K shares valued at $6.45K. A 0.16% stake in KALA BIO, Inc. is owned by the company. BLACKROCK, INC. owns 21.41K shares valued at $11.90K, which translates its holding of 0.3% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Dec 31, 2025	CITIGROUP INC	0.16%	11.6K	6.45K	10.88K	+1,508.32%
Dec 31, 2025	BLACKROCK, INC.	0.3%	21.41K	11.9K	0	0
Dec 31, 2025	UBS GROUP AG	0.34%	23.91K	13.29K	15.72K	+191.83%
Dec 31, 2025	TWO SIGMA INVESTMENTS, LP	0.38%	26.9K	14.95K	26.9K	+100.00%
Dec 31, 2025	BAKER BROS. ADVISORS LP	25.62%	1.8M	1M	818.96K	+83.14%
Dec 31, 2025	XTX TOPCO LTD	0.4%	28.28K	15.72K	28.28K	+100.00%
Dec 31, 2025	STATE STREET CORP	0.41%	28.58K	15.89K	0	0
Dec 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0.58%	40.91K	22.74K	40.91K	+100.00%
Dec 31, 2025	CITADEL ADVISORS LLC	0.8%	56.38K	31.34K	56.38K	+100.00%
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.87%	61.16K	34.01K	-6.75K	-9.94%
Dec 31, 2025	VANGUARD GROUP INC	1.29%	91.01K	50.6K	-119.82K	-56.83%
Dec 31, 2025	JANE STREET GROUP, LLC	2.05%	144.35K	80.24K	144.35K	+100.00%
Dec 31, 2025	STEWARD PARTNERS INVESTMENT ADVISORY, LLC	0%	120	67	0	0
Dec 31, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0%	0	-	-5.08K	-100.00%
Dec 31, 2025	STONEX GROUP INC.	0.17%	12.26K	6.81K	12.26K	+100.00%
Dec 31, 2025	SG AMERICAS SECURITIES, LLC	0.15%	10.36K	6K	10.36K	+100.00%
Dec 31, 2025	CAITONG INTERNATIONAL ASSET MANAGEMENT CO., LTD	0%	0	-	-736	-100.00%
Dec 31, 2025	LEGACY WEALTH MANAGMENT, LLC/ID	0%	25	14	0	0
Dec 31, 2025	INTERNATIONAL ASSETS INVESTMENT MANAGEMENT, LLC	0%	110	61	110	+100.00%
Dec 31, 2025	COVESTOR LTD	0.02%	1.26K	1K	0	0
Dec 31, 2025	WOODLINE PARTNERS LP	3.18%	224.17K	124.62K	-23.29K	-9.41%
Dec 31, 2025	PNC FINANCIAL SERVICES GROUP, INC.	0%	0	-	-46	-100.00%
Dec 31, 2025	MAI CAPITAL MANAGEMENT	0%	300	167	0	0
Dec 31, 2025	MORGAN STANLEY	0.01%	607	338	-926	-60.40%
Dec 31, 2025	NORTHERN TRUST CORP	0.16%	11.52K	6.41K	0	0
Dec 31, 2025	TWO SIGMA SECURITIES, LLC	0.19%	13.11K	7.29K	13.11K	+100.00%
Dec 31, 2025	BANK OF AMERICA CORP /DE/	0%	296	165	-1.23K	-80.56%
Dec 31, 2025	JPMORGAN CHASE & CO	0%	51	29	0	0
Dec 31, 2025	VIRTU FINANCIAL LLC	1.21%	85.51K	48K	85.51K	+100.00%
Dec 31, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	2.01%	141.48K	78.65K	-515	-0.36%
Dec 31, 2025	MAREX GROUP PLC	0%	0	-	-14.5K	-100.00%
Dec 31, 2025	SBI SECURITIES CO., LTD.	0%	8	4	0	0
Sep 30, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0.08%	5.08K	7.77K	3.93K	+344.09%
Sep 30, 2025	PNC FINANCIAL SERVICES GROUP, INC.	0%	46	70	46	+100.00%
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0%	0	-	-17.4K	-100.00%
Sep 30, 2025	ADVISOR GROUP HOLDINGS, INC.	0%	0	-	-100	-100.00%
Sep 30, 2025	CORMORANT ASSET MANAGEMENT, LP	0%	0	-	-603.03K	-100.00%
Sep 30, 2025	PERCEPTIVE ADVISORS LLC	0%	0	-	-55.23K	-100.00%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0%	0	-	-98	-100.00%
Sep 30, 2025	UBS OCONNOR LLC	0%	0	-	-138.56K	-100.00%
Sep 30, 2025	MORGAN STANLEY	0.02%	1.53K	2.35K	561	+57.72%
Sep 30, 2025	UBS GROUP AG	0.13%	8.19K	12.54K	8.16K	+23,997.06%
Sep 30, 2025	VANGUARD GROUP INC	3.24%	210.83K	322.56K	40.45K	+23.74%
Sep 30, 2025	JPMORGAN CHASE & CO	0%	51	78	-186	-78.48%
Sep 30, 2025	SBI SECURITIES CO., LTD.	0%	8	12	0	0
Sep 30, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	2.18%	142K	217.25K	-7.84K	-5.23%
Sep 30, 2025	MAREX GROUP PLC	0.22%	14.5K	35.02K	14.5K	+100.00%
Sep 30, 2025	AIGH CAPITAL MANAGEMENT LLC	0%	0	-	-300K	-100.00%
Sep 30, 2025	SR ONE CAPITAL MANAGEMENT, LP	0%	0	-	-598.94K	-100.00%
Sep 30, 2025	RAYMOND JAMES FINANCIAL INC	0%	0	-	-7	-100.00%
Sep 30, 2025	LEGACY WEALTH MANAGMENT, LLC/ID	0%	25	39	0	0
Sep 30, 2025	BLACKROCK, INC.	0.33%	21.41K	32.75K	51	+0.24%
Sep 30, 2025	CAITONG INTERNATIONAL ASSET MANAGEMENT CO., LTD	0.01%	736	1.13K	736	+100.00%
Sep 30, 2025	MAI CAPITAL MANAGEMENT	0%	300	459	0	0
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.02%	1.52K	2.33K	1.43K	+1,454.08%
Sep 30, 2025	WOODLINE PARTNERS LP	3.8%	247.47K	378.62K	-52.68K	-17.55%
Sep 30, 2025	BAKER BROS. ADVISORS LP	15.12%	985.09K	1.51M	-216.8K	-18.04%
Sep 30, 2025	XTX TOPCO LTD	0%	0	-	-12.99K	-100.00%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.04%	67.91K	103.95K	11.55K	+20.48%
Sep 30, 2025	NORTHERN TRUST CORP	0.18%	11.52K	17.63K	1.13K	+10.82%
Sep 30, 2025	COVESTOR LTD	0.02%	1.26K	2K	126	+11.07%
Sep 30, 2025	CITIGROUP INC	0.01%	721	1.1K	721	+100.00%
Sep 30, 2025	STEWARD PARTNERS INVESTMENT ADVISORY, LLC	0%	120	184	0	0
Sep 30, 2025	STATE STREET CORP	0.44%	28.58K	43.72K	28.58K	+100.00%
Jun 30, 2025	JPMORGAN CHASE & CO	0%	237	1.13K	177	+295.00%
Jun 30, 2025	SR ONE CAPITAL MANAGEMENT, LP	9.2%	598.94K	2.85M	0	0
Jun 30, 2025	WOODLINE PARTNERS LP	4.61%	300.15K	1.43M	41.38K	+15.99%
Jun 30, 2025	NORTHERN TRUST CORP	0.16%	10.4K	49.5K	0	0
Jun 30, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0.02%	1.14K	5.44K	922	+417.19%
Jun 30, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	2.3%	149.83K	713.19K	-149.13K	-49.88%
Jun 30, 2025	BLACKROCK, INC.	0.33%	21.36K	101.66K	0	0
Jun 30, 2025	UBS OCONNOR LLC	2.13%	138.56K	659.53K	-32.36K	-18.93%
Jun 30, 2025	MAI CAPITAL MANAGEMENT	0%	300	1.43K	0	0
Jun 30, 2025	BAKER BROS. ADVISORS LP	18.45%	1.2M	5.72M	0	0
Jun 30, 2025	CORMORANT ASSET MANAGEMENT, LP	9.26%	603.03K	2.87M	0	0
Jun 30, 2025	PERCEPTIVE ADVISORS LLC	0.85%	55.23K	262.88K	-222.38K	-80.11%
Jun 30, 2025	STEWARD PARTNERS INVESTMENT ADVISORY, LLC	0%	120	571	0	0
Jun 30, 2025	COVESTOR LTD	0.02%	1.14K	5K	-2	-0.18%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0%	98	466	49	+100.00%
Jun 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0%	98	466	0	0
Jun 30, 2025	RAYMOND JAMES FINANCIAL INC	0%	7	33	7	+100.00%
Jun 30, 2025	UBS GROUP AG	0%	34	162	-3.38K	-99.00%
Jun 30, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0%	0	-	-246.08K	-100.00%
Jun 30, 2025	READYSTATE ASSET MANAGEMENT LP	0%	0	-	-42.46K	-100.00%
Jun 30, 2025		0%	0	-	-8	-100.00%
Jun 30, 2025	AIGH CAPITAL MANAGEMENT LLC	4.61%	300K	1.43M	103.65K	+52.79%
Jun 30, 2025	MORGAN STANLEY	0.01%	972	4.63K	0	0
Jun 30, 2025	XTX TOPCO LTD	0.2%	12.99K	61.83K	12.99K	+100.00%
Jun 30, 2025	VANGUARD GROUP INC	2.62%	170.38K	810.99K	17.6K	+11.52%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.87%	56.37K	268.34K	1.53K	+2.80%
Jun 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.27%	17.4K	82.82K	17.4K	+100.00%
Jun 30, 2025	ADVISOR GROUP HOLDINGS, INC.	0%	100	476	100	+100.00%
Jun 30, 2025	LEGACY INVESTMENT SOLUTIONS, LLC	0%	25	119	25	+100.00%
Jun 30, 2025	LEGACY WEALTH MANAGMENT, LLC/ID	0%	25	119	0	0
Jun 30, 2025	SBI SECURITIES CO., LTD.	0%	8	38	0	0
Jun 30, 2025	CURIO WEALTH, LLC	0%	0	-	-1	-100.00%
Jun 30, 2025	BINNACLE INVESTMENTS INC	0%	0	-	-8	-100.00%
Mar 31, 2025	BAKER BROS. ADVISORS LP	18.94%	1.2M	6.89M	0	0
Mar 31, 2025	ADVISOR GROUP HOLDINGS, INC.	0%	0	-	-100	-100.00%
Mar 31, 2025	BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY	0%	0	-	-21.13K	-100.00%
Mar 31, 2025	CWM, LLC	0%	0	-	-200	-100.00%
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	0%	0	-	-136.06K	-100.00%
Mar 31, 2025	TWO SIGMA INVESTMENTS, LP	0%	0	-	-11.88K	-100.00%
Mar 31, 2025	GROUP ONE TRADING, L.P.	0%	0	-	-22	-100.00%
Mar 31, 2025	JPMORGAN CHASE & CO	0%	60	344	0	0
Mar 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0%	98	562	0	0
Mar 31, 2025	STEWARD PARTNERS INVESTMENT ADVISORY, LLC	0%	120	688	0	0
Mar 31, 2025	CHEVIOT VALUE MANAGEMENT, LLC	0%	153	555	153	+100.00%
Mar 31, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0%	221	1.27K	-491	-68.96%
Mar 31, 2025	MAI CAPITAL MANAGEMENT	0%	300	1.72K	0	0
Mar 31, 2025	UBS GROUP AG	0.05%	3.41K	19.56K	259	+8.21%
Mar 31, 2025	MORGAN STANLEY	0.02%	972	5.57K	0	0
Mar 31, 2025	COVESTOR LTD	0.02%	1.14K	7K	171	+17.65%
Mar 31, 2025	CITIGROUP INC	0%	0	-	-5.68K	-100.00%
Mar 31, 2025		0%	1	139	-19	-95.00%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0%	49	281	12	+32.43%
Mar 31, 2025	AIGH CAPITAL MANAGEMENT LLC	3.09%	196.35K	1.13M	75.05K	+61.87%
Mar 31, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	3.88%	246.08K	1.41M	15.01K	+6.50%
Mar 31, 2025	PERCEPTIVE ADVISORS LLC	4.37%	277.61K	1.59M	277.61K	+100.00%
Mar 31, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	4.71%	298.96K	1.71M	78.58K	+35.66%
Mar 31, 2025	SR ONE CAPITAL MANAGEMENT, LP	9.44%	598.94K	3.43M	0	0
Mar 31, 2025	CORMORANT ASSET MANAGEMENT, LP	9.5%	603.03K	3.46M	0	0
Mar 31, 2025	COMPAGNIE LOMBARD ODIER SCMA	0%	0	-	-400	-100.00%
Mar 31, 2025	PARALLEL ADVISORS, LLC	0%	1	6	0	0
Mar 31, 2025	NORTHERN TRUST CORP	0.16%	10.4K	59.59K	10.4K	+100.00%
Mar 31, 2025	BLACKROCK, INC.	0.34%	21.36K	122.37K	0	0
Mar 31, 2025	READYSTATE ASSET MANAGEMENT LP	0.67%	42.46K	243.29K	42.46K	+100.00%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.86%	54.83K	314.24K	7.19K	+15.09%
Mar 31, 2025	VANGUARD GROUP INC	2.41%	152.78K	875.4K	99.21K	+185.19%
Mar 31, 2025	WOODLINE PARTNERS LP	4.08%	258.77K	1.48M	258.77K	+100.00%
Mar 31, 2025	UBS OCONNOR LLC	2.69%	170.92K	979.35K	-8.02K	-4.48%
Mar 31, 2024	PARALLEL ADVISORS, LLC	0%	1	8	0	0
Dec 31, 2023	PARALLEL ADVISORS, LLC	0%	1	7	0	0
Sep 30, 2023	FIDUCIARY ALLIANCE LLC	0%	0	-	-95	-100.00%
Sep 30, 2023	WORTH ASSET MANAGEMENT, LLC	0%	0	-	-10	-100.00%
Sep 30, 2023	PARALLEL ADVISORS, LLC	0%	1	9	0	0

Insiders

Among the KALA insiders holding of 1.75% of the stake in company, SHAH RAJEEV M., , holds the largest shares of 7.04M. RA CAPITAL MANAGEMENT, L.P., 10 percent owner, is the second largest KALA insider with ownership of 7.04M shares. RA CAPITAL MANAGEMENT, LLC, , stands third with possession of 4.54M shares of that stake.

Insiders	Designation	Shares Held
SHAH RAJEEV M.		7.04M
RA CAPITAL MANAGEMENT, L.P.	10 percent owner	7.04M
RA CAPITAL MANAGEMENT, LLC		4.54M
ORBIMED ADVISORS LLC	10 percent owner	3.45M
GRUNBERG GREGORY	director	2.53M
LONGITUDE CAPITAL PARTNERS II, LLC	10 percent owner	2.27M
CDK ASSOCIATES, L.L.C.	10 percent owner	215K
CHEN HONGMING	CHIEF SCIENTIFIC OFFICER	204.52K
IWICKI MARK T	director	103.54K
TRACHTENBERG ERIC	SEE REMARKS	68.07K
BAKER BROS. ADVISORS LP	Former 10% owner	46.48K
KHARABI DARIUS	CHIEF BUSINESS OFFICER	41.76K
BRAZZELL ROMULUS K	SEE REMARKS	35.95K
BAZEMORE TODD	director	35.93K
REUMUTH MARY	CHIEF FINANCIAL OFFICER	28.91K
ROSEN HOWARD B	director	8.24K

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Oct 23, 2025	REUMUTH MARY	SALE	0.82	967	792.94	28.91K
Oct 23, 2025	IWICKI MARK T	SALE	0.81	154.89K	125.46K	103.54K
Oct 22, 2025	BRAZZELL ROMULUS K	SALE	0.83	46.75K	38.8K	35.95K
Oct 22, 2025	KHARABI DARIUS	SALE	0.83	20.81K	17.27K	41.76K
Oct 22, 2025	BAZEMORE TODD	SALE	0.83	47.77K	39.65K	35.93K
Oct 22, 2025	REUMUTH MARY	SALE	0.83	32.23K	26.75K	29.87K
Oct 01, 2025	BAKER BROS. ADVISORS LP	SALE	1.38	50.64K	70.08K	46.48K
Sep 30, 2025	BAKER BROS. ADVISORS LP	SALE	1.60	21.38K	34.11K	97.12K
Jun 24, 2025	IWICKI MARK T	SALE	4.01	13.23K	53.04K	258.43K
Jun 24, 2025	KHARABI DARIUS	SALE	4.01	4.51K	18.09K	62.57K
Jun 24, 2025	REUMUTH MARY	SALE	4.01	3.63K	14.56K	62.1K
Jun 24, 2025	BAZEMORE TODD	SALE	4.01	4.06K	16.27K	83.7K
Jun 24, 2025	BRAZZELL ROMULUS K	SALE	4.01	5.25K	21.06K	82.7K
Jun 03, 2025	IWICKI MARK T	SALE	3.74	10.87K	40.64K	269.21K
Jun 03, 2025	KHARABI DARIUS	SALE	3.74	730	2.73K	67.08K
Jun 03, 2025	REUMUTH MARY	SALE	3.74	2.85K	10.66K	65.73K
Jun 03, 2025	BRAZZELL ROMULUS K	SALE	3.74	3.69K	13.79K	87.95K
Jun 03, 2025	BAZEMORE TODD	SALE	3.74	3.39K	12.68K	87.76K
Jan 06, 2025	IWICKI MARK T	SALE	7.63	5.78K	44.09K	280.08K
Jan 06, 2025	BAZEMORE TODD	SALE	7.63	1.99K	15.21K	0
Jan 06, 2025	KHARABI DARIUS	SALE	7.63	2.02K	15.42K	67.81K
Jan 06, 2025	REUMUTH MARY	SALE	7.63	1.71K	13.02K	68.58K
Jan 06, 2025	BRAZZELL ROMULUS K	SALE	7.63	2.45K	18.66K	92.42K
Dec 30, 2024	BAKER BROS. ADVISORS LP	PURCHASE	6.44	30.62K	197.19K	118.5K
Jun 26, 2024	KHARABI DARIUS	SALE	4.75	5.16K	24.5K	59.73K
Jun 26, 2024	BAZEMORE TODD	SALE	4.75	4.65K	22.1K	83.04K
Jun 26, 2024	IWICKI MARK T	SALE	4.75	15.17K	72.05K	263.76K
Jun 26, 2024	BRAZZELL ROMULUS K	SALE	4.75	5.49K	26.07K	83.98K
Jun 26, 2024	REUMUTH MARY	SALE	4.75	4.16K	19.77K	60.19K
May 31, 2024	REUMUTH MARY	SALE	6.09	1.79K	10.88K	64.35K
May 31, 2024	BAZEMORE TODD	SALE	6.09	2.09K	12.75K	87.69K
May 31, 2024	BRAZZELL ROMULUS K	SALE	6.09	2K	12.19K	89.47K
May 31, 2024	IWICKI MARK T	SALE	6.09	7.39K	45.02K	278.92K
May 31, 2024	KHARABI DARIUS	SALE	6.09	231	1.41K	64.89K
Jan 04, 2024	IWICKI MARK T	SALE	6.73	4.54K	30.55K	286.32K
Jan 04, 2024	REUMUTH MARY	SALE	6.74	1.23K	8.27K	66.14K
Jan 04, 2024	BAZEMORE TODD	SALE	6.74	1.41K	9.47K	0
Jan 04, 2024	TRACHTENBERG ERIC	SALE	6.74	1.23K	8.27K	68.07K
Jan 04, 2024	BRAZZELL ROMULUS K	SALE	6.74	1.62K	10.9K	91.47K
Jan 04, 2024	KHARABI DARIUS	SALE	6.73	1.39K	9.32K	65.12K
Jan 04, 2023	IWICKI MARK T	SALE	28.54	198	5.65K	45.97K
Jan 04, 2023	BRAZZELL ROMULUS K	SALE	28.53	73	2.08K	18.54K
Jan 04, 2023	TRACHTENBERG ERIC	SALE	28.55	60	1.71K	11.5K
Jan 04, 2023	REUMUTH MARY	SALE	28.54	60	1.71K	11.88K
Jan 04, 2023	BAZEMORE TODD	SALE	28.54	62	1.77K	14.84K
Oct 26, 2022	IWICKI MARK T	SALE	6.52	561	3.66K	4.46K
Oct 26, 2022	BRAZZELL ROMULUS K	SALE	6.51	261	1.7K	5.81K
Oct 26, 2022	REUMUTH MARY	SALE	6.51	194	1.26K	2.42K
Oct 26, 2022	TRACHTENBERG ERIC	SALE	6.52	194	1.26K	2.03K
Oct 26, 2022	BAZEMORE TODD	SALE	6.51	214	1.39K	2.1K
Jun 27, 2022	TRACHTENBERG ERIC	SALE	0.37	2.61K	966.81	111.2K
Jun 27, 2022	BAZEMORE TODD	SALE	0.37	3.09K	1.14K	115.5K
Jun 27, 2022	IWICKI MARK T	SALE	0.37	7.98K	2.95K	251.18K
Jun 27, 2022	BRAZZELL ROMULUS K	SALE	0.37	3.14K	1.16K	285.2K
Jun 27, 2022	REUMUTH MARY	SALE	0.37	2.61K	966.81	130.6K
May 26, 2022	RA CAPITAL MANAGEMENT, L.P.	SALE	0.36	1.01M	365.67K	7.04M
May 26, 2022	SHAH RAJEEV M.	SALE	0.36	1.01M	365.67K	7.04M
May 25, 2022	RA CAPITAL MANAGEMENT, L.P.	SALE	0.42	1.43M	602.49K	8.05M
May 24, 2022	RA CAPITAL MANAGEMENT, L.P.	SALE	0.51	144.81K	73.85K	9.48M
May 23, 2022	SHAH RAJEEV M.	SALE	0.65	1.25M	812.5K	9.62M
May 23, 2022	RA CAPITAL MANAGEMENT, L.P.	SALE	0.65	1.25M	812.5K	9.62M
Jan 04, 2022	REUMUTH MARY	SALE	1.30	2.85K	3.71K	133.21K
Jan 04, 2022	TRACHTENBERG ERIC	SALE	1.30	2.85K	3.71K	113.82K
Jan 04, 2022	IWICKI MARK T	SALE	1.30	9.52K	12.37K	259.16K
Jan 04, 2022	BRAZZELL ROMULUS K	SALE	1.30	3.5K	4.56K	288.35K
Jan 04, 2022	BAZEMORE TODD	SALE	1.30	3.45K	4.49K	118.59K
Oct 27, 2021	CHEN HONGMING	SALE	1.82	21.05K	38.31K	204.52K
Oct 26, 2021	BRAZZELL ROMULUS K	SALE	1.80	12.76K	22.96K	291.85K
Oct 26, 2021	REUMUTH MARY	SALE	1.80	9.45K	17.01K	136.06K
Oct 26, 2021	CHEN HONGMING	SALE	1.80	9.45K	17.01K	225.57K
Oct 26, 2021	TRACHTENBERG ERIC	SALE	1.80	9.45K	17.01K	116.67K
Oct 26, 2021	IWICKI MARK T	SALE	1.80	27.6K	49.68K	268.68K
Oct 26, 2021	BAZEMORE TODD	SALE	1.80	12.54K	22.58K	122.05K
Jun 29, 2021	CHEN HONGMING	SALE	5.56	5.55K	30.85K	235.02K
Jun 28, 2021	IWICKI MARK T	SALE	5.77	7.59K	43.77K	296.27K
Jun 28, 2021	BRAZZELL ROMULUS K	SALE	5.77	3.03K	17.51K	300.96K
Jun 28, 2021	TRACHTENBERG ERIC	SALE	5.77	2.45K	14.15K	126.12K
Jun 28, 2021	REUMUTH MARY	SALE	5.77	2.45K	14.15K	145.51K
Jun 28, 2021	CHEN HONGMING	SALE	5.77	2.45K	14.15K	240.56K
Jun 28, 2021	BAZEMORE TODD	SALE	5.77	2.91K	16.8K	0
Oct 22, 2020	BAZEMORE TODD	PURCHASE	7.60	40	304	42
Jun 05, 2020	BAZEMORE TODD	PURCHASE	13.39	2	26.78	2
Mar 16, 2020	BAZEMORE TODD	PURCHASE	5.75	10K	57.5K	10K
Mar 13, 2020	SHAH RAJEEV M.	PURCHASE	7.89	6.34M	50M	10.87M
Mar 13, 2020	RA CAPITAL MANAGEMENT, L.P.	PURCHASE	7.89	6.34M	50M	10.87M
Mar 13, 2020	GRUNBERG GREGORY	PURCHASE	7.89	2.53M	20M	2.53M
May 30, 2019	ROSEN HOWARD B	PURCHASE	5.42	5K	27.1K	8.24K
Oct 05, 2018	GRUNBERG GREGORY	PURCHASE	8.25	606.06K	5M	2.88M
Oct 03, 2018	SHAH RAJEEV M.	PURCHASE	8.25	2.42M	20M	4.54M
Oct 03, 2018	RA CAPITAL MANAGEMENT, LLC	PURCHASE	8.25	2.42M	20M	4.54M
Feb 08, 2018	ORBIMED ADVISORS LLC	PURCHASE	12.93	25K	323.25K	3.45M
Feb 02, 2018	ORBIMED ADVISORS LLC	PURCHASE	14.73	37.84K	557.38K	3.42M
Feb 01, 2018	ORBIMED ADVISORS LLC	PURCHASE	14.99	22.84K	342.37K	3.39M
Jan 31, 2018	ORBIMED ADVISORS LLC	PURCHASE	15.00	339.4K	5.09M	3.36M
Jan 29, 2018	ORBIMED ADVISORS LLC	PURCHASE	14.99	50K	749.5K	3.02M
Jan 26, 2018	ORBIMED ADVISORS LLC	PURCHASE	14.93	22.76K	339.81K	2.97M
Jan 24, 2018	ORBIMED ADVISORS LLC	PURCHASE	14.91	64.64K	963.74K	2.95M
Jan 23, 2018	ORBIMED ADVISORS LLC	PURCHASE	14.99	4.36K	65.4K	2.89M
Jan 22, 2018	ORBIMED ADVISORS LLC	PURCHASE	14.98	75K	1.12M	2.88M
Jan 19, 2018	ORBIMED ADVISORS LLC	PURCHASE	14.95	74.93K	1.12M	2.81M
Jan 12, 2018	ORBIMED ADVISORS LLC	PURCHASE	15.40	28.45K	438.07K	2.69M
Jan 11, 2018	ORBIMED ADVISORS LLC	PURCHASE	13.65	41.7K	569.21K	2.66M
Jan 10, 2018	ORBIMED ADVISORS LLC	PURCHASE	12.83	170.34K	2.19M	2.62M
Jul 25, 2017	GRUNBERG GREGORY	PURCHASE	15.00	215K	3.23M	2.27M
Jul 25, 2017	LONGITUDE CAPITAL PARTNERS II, LLC	PURCHASE	15.00	215K	3.23M	2.27M
Jul 25, 2017	ORBIMED ADVISORS LLC	PURCHASE	15.00	319.33K	4.79M	2.38M
Jul 25, 2017	RA CAPITAL MANAGEMENT, LLC	PURCHASE	15.00	533.33K	8M	2.11M
Jul 25, 2017	SHAH RAJEEV M.	PURCHASE	15.00	533.33K	8M	2.11M
Jul 20, 2017	CDK ASSOCIATES, L.L.C.	PURCHASE	15.00	215K	3.23M	215K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES375.43K8

NET SHARES-375.43K8

SHARES HELD419.56K8

% NET SHARES-189.48%0%

Frequently Asked Questions

Stock Outstanding Shares

ShortableYes

OptionableNo

Short Percent Of Outstanding Shares5.4

Short Percent Of Float6.87

Shares Outstanding7.02M

Shares Float4.25M

Shares Short348.23K

Short Ratio1.71

6.87%

Short % of Float

5.4%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

1.75% Percentage of Shares held by All Insiders

51.86% Percentage of Shares held by All Institutions

52.79% Percentage of Float held by Institutions

Number of Institutions Holding Shares

Institutional Ownership

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Dec 31, 2025	CITIGROUP INC	0.16%	11.6K	6.45K	10.88K	+1,508.32%
Dec 31, 2025	BLACKROCK, INC.	0.3%	21.41K	11.9K	0	0
Dec 31, 2025	UBS GROUP AG	0.34%	23.91K	13.29K	15.72K	+191.83%
Dec 31, 2025	TWO SIGMA INVESTMENTS, LP	0.38%	26.9K	14.95K	26.9K	+100.00%
Dec 31, 2025	BAKER BROS. ADVISORS LP	25.62%	1.8M	1M	818.96K	+83.14%
Dec 31, 2025	XTX TOPCO LTD	0.4%	28.28K	15.72K	28.28K	+100.00%
Dec 31, 2025	STATE STREET CORP	0.41%	28.58K	15.89K	0	0
Dec 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0.58%	40.91K	22.74K	40.91K	+100.00%
Dec 31, 2025	CITADEL ADVISORS LLC	0.8%	56.38K	31.34K	56.38K	+100.00%
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.87%	61.16K	34.01K	-6.75K	-9.94%
Dec 31, 2025	VANGUARD GROUP INC	1.29%	91.01K	50.6K	-119.82K	-56.83%
Dec 31, 2025	JANE STREET GROUP, LLC	2.05%	144.35K	80.24K	144.35K	+100.00%
Dec 31, 2025	STEWARD PARTNERS INVESTMENT ADVISORY, LLC	0%	120	67	0	0
Dec 31, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0%	0	-	-5.08K	-100.00%
Dec 31, 2025	STONEX GROUP INC.	0.17%	12.26K	6.81K	12.26K	+100.00%
Dec 31, 2025	SG AMERICAS SECURITIES, LLC	0.15%	10.36K	6K	10.36K	+100.00%
Dec 31, 2025	CAITONG INTERNATIONAL ASSET MANAGEMENT CO., LTD	0%	0	-	-736	-100.00%
Dec 31, 2025	LEGACY WEALTH MANAGMENT, LLC/ID	0%	25	14	0	0
Dec 31, 2025	INTERNATIONAL ASSETS INVESTMENT MANAGEMENT, LLC	0%	110	61	110	+100.00%
Dec 31, 2025	COVESTOR LTD	0.02%	1.26K	1K	0	0
Dec 31, 2025	WOODLINE PARTNERS LP	3.18%	224.17K	124.62K	-23.29K	-9.41%
Dec 31, 2025	PNC FINANCIAL SERVICES GROUP, INC.	0%	0	-	-46	-100.00%
Dec 31, 2025	MAI CAPITAL MANAGEMENT	0%	300	167	0	0
Dec 31, 2025	MORGAN STANLEY	0.01%	607	338	-926	-60.40%
Dec 31, 2025	NORTHERN TRUST CORP	0.16%	11.52K	6.41K	0	0
Dec 31, 2025	TWO SIGMA SECURITIES, LLC	0.19%	13.11K	7.29K	13.11K	+100.00%
Dec 31, 2025	BANK OF AMERICA CORP /DE/	0%	296	165	-1.23K	-80.56%
Dec 31, 2025	JPMORGAN CHASE & CO	0%	51	29	0	0
Dec 31, 2025	VIRTU FINANCIAL LLC	1.21%	85.51K	48K	85.51K	+100.00%
Dec 31, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	2.01%	141.48K	78.65K	-515	-0.36%
Dec 31, 2025	MAREX GROUP PLC	0%	0	-	-14.5K	-100.00%
Dec 31, 2025	SBI SECURITIES CO., LTD.	0%	8	4	0	0
Sep 30, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0.08%	5.08K	7.77K	3.93K	+344.09%
Sep 30, 2025	PNC FINANCIAL SERVICES GROUP, INC.	0%	46	70	46	+100.00%
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0%	0	-	-17.4K	-100.00%
Sep 30, 2025	ADVISOR GROUP HOLDINGS, INC.	0%	0	-	-100	-100.00%
Sep 30, 2025	CORMORANT ASSET MANAGEMENT, LP	0%	0	-	-603.03K	-100.00%
Sep 30, 2025	PERCEPTIVE ADVISORS LLC	0%	0	-	-55.23K	-100.00%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0%	0	-	-98	-100.00%
Sep 30, 2025	UBS OCONNOR LLC	0%	0	-	-138.56K	-100.00%
Sep 30, 2025	MORGAN STANLEY	0.02%	1.53K	2.35K	561	+57.72%
Sep 30, 2025	UBS GROUP AG	0.13%	8.19K	12.54K	8.16K	+23,997.06%
Sep 30, 2025	VANGUARD GROUP INC	3.24%	210.83K	322.56K	40.45K	+23.74%
Sep 30, 2025	JPMORGAN CHASE & CO	0%	51	78	-186	-78.48%
Sep 30, 2025	SBI SECURITIES CO., LTD.	0%	8	12	0	0
Sep 30, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	2.18%	142K	217.25K	-7.84K	-5.23%
Sep 30, 2025	MAREX GROUP PLC	0.22%	14.5K	35.02K	14.5K	+100.00%
Sep 30, 2025	AIGH CAPITAL MANAGEMENT LLC	0%	0	-	-300K	-100.00%
Sep 30, 2025	SR ONE CAPITAL MANAGEMENT, LP	0%	0	-	-598.94K	-100.00%
Sep 30, 2025	RAYMOND JAMES FINANCIAL INC	0%	0	-	-7	-100.00%
Sep 30, 2025	LEGACY WEALTH MANAGMENT, LLC/ID	0%	25	39	0	0
Sep 30, 2025	BLACKROCK, INC.	0.33%	21.41K	32.75K	51	+0.24%
Sep 30, 2025	CAITONG INTERNATIONAL ASSET MANAGEMENT CO., LTD	0.01%	736	1.13K	736	+100.00%
Sep 30, 2025	MAI CAPITAL MANAGEMENT	0%	300	459	0	0
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.02%	1.52K	2.33K	1.43K	+1,454.08%
Sep 30, 2025	WOODLINE PARTNERS LP	3.8%	247.47K	378.62K	-52.68K	-17.55%
Sep 30, 2025	BAKER BROS. ADVISORS LP	15.12%	985.09K	1.51M	-216.8K	-18.04%
Sep 30, 2025	XTX TOPCO LTD	0%	0	-	-12.99K	-100.00%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.04%	67.91K	103.95K	11.55K	+20.48%
Sep 30, 2025	NORTHERN TRUST CORP	0.18%	11.52K	17.63K	1.13K	+10.82%
Sep 30, 2025	COVESTOR LTD	0.02%	1.26K	2K	126	+11.07%
Sep 30, 2025	CITIGROUP INC	0.01%	721	1.1K	721	+100.00%
Sep 30, 2025	STEWARD PARTNERS INVESTMENT ADVISORY, LLC	0%	120	184	0	0
Sep 30, 2025	STATE STREET CORP	0.44%	28.58K	43.72K	28.58K	+100.00%
Jun 30, 2025	JPMORGAN CHASE & CO	0%	237	1.13K	177	+295.00%
Jun 30, 2025	SR ONE CAPITAL MANAGEMENT, LP	9.2%	598.94K	2.85M	0	0
Jun 30, 2025	WOODLINE PARTNERS LP	4.61%	300.15K	1.43M	41.38K	+15.99%
Jun 30, 2025	NORTHERN TRUST CORP	0.16%	10.4K	49.5K	0	0
Jun 30, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0.02%	1.14K	5.44K	922	+417.19%
Jun 30, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	2.3%	149.83K	713.19K	-149.13K	-49.88%
Jun 30, 2025	BLACKROCK, INC.	0.33%	21.36K	101.66K	0	0
Jun 30, 2025	UBS OCONNOR LLC	2.13%	138.56K	659.53K	-32.36K	-18.93%
Jun 30, 2025	MAI CAPITAL MANAGEMENT	0%	300	1.43K	0	0
Jun 30, 2025	BAKER BROS. ADVISORS LP	18.45%	1.2M	5.72M	0	0
Jun 30, 2025	CORMORANT ASSET MANAGEMENT, LP	9.26%	603.03K	2.87M	0	0
Jun 30, 2025	PERCEPTIVE ADVISORS LLC	0.85%	55.23K	262.88K	-222.38K	-80.11%
Jun 30, 2025	STEWARD PARTNERS INVESTMENT ADVISORY, LLC	0%	120	571	0	0
Jun 30, 2025	COVESTOR LTD	0.02%	1.14K	5K	-2	-0.18%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0%	98	466	49	+100.00%
Jun 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0%	98	466	0	0
Jun 30, 2025	RAYMOND JAMES FINANCIAL INC	0%	7	33	7	+100.00%
Jun 30, 2025	UBS GROUP AG	0%	34	162	-3.38K	-99.00%
Jun 30, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0%	0	-	-246.08K	-100.00%
Jun 30, 2025	READYSTATE ASSET MANAGEMENT LP	0%	0	-	-42.46K	-100.00%
Jun 30, 2025		0%	0	-	-8	-100.00%
Jun 30, 2025	AIGH CAPITAL MANAGEMENT LLC	4.61%	300K	1.43M	103.65K	+52.79%
Jun 30, 2025	MORGAN STANLEY	0.01%	972	4.63K	0	0
Jun 30, 2025	XTX TOPCO LTD	0.2%	12.99K	61.83K	12.99K	+100.00%
Jun 30, 2025	VANGUARD GROUP INC	2.62%	170.38K	810.99K	17.6K	+11.52%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.87%	56.37K	268.34K	1.53K	+2.80%
Jun 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.27%	17.4K	82.82K	17.4K	+100.00%
Jun 30, 2025	ADVISOR GROUP HOLDINGS, INC.	0%	100	476	100	+100.00%
Jun 30, 2025	LEGACY INVESTMENT SOLUTIONS, LLC	0%	25	119	25	+100.00%
Jun 30, 2025	LEGACY WEALTH MANAGMENT, LLC/ID	0%	25	119	0	0
Jun 30, 2025	SBI SECURITIES CO., LTD.	0%	8	38	0	0
Jun 30, 2025	CURIO WEALTH, LLC	0%	0	-	-1	-100.00%
Jun 30, 2025	BINNACLE INVESTMENTS INC	0%	0	-	-8	-100.00%
Mar 31, 2025	BAKER BROS. ADVISORS LP	18.94%	1.2M	6.89M	0	0
Mar 31, 2025	ADVISOR GROUP HOLDINGS, INC.	0%	0	-	-100	-100.00%
Mar 31, 2025	BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY	0%	0	-	-21.13K	-100.00%
Mar 31, 2025	CWM, LLC	0%	0	-	-200	-100.00%
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	0%	0	-	-136.06K	-100.00%
Mar 31, 2025	TWO SIGMA INVESTMENTS, LP	0%	0	-	-11.88K	-100.00%
Mar 31, 2025	GROUP ONE TRADING, L.P.	0%	0	-	-22	-100.00%
Mar 31, 2025	JPMORGAN CHASE & CO	0%	60	344	0	0
Mar 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0%	98	562	0	0
Mar 31, 2025	STEWARD PARTNERS INVESTMENT ADVISORY, LLC	0%	120	688	0	0
Mar 31, 2025	CHEVIOT VALUE MANAGEMENT, LLC	0%	153	555	153	+100.00%
Mar 31, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0%	221	1.27K	-491	-68.96%
Mar 31, 2025	MAI CAPITAL MANAGEMENT	0%	300	1.72K	0	0
Mar 31, 2025	UBS GROUP AG	0.05%	3.41K	19.56K	259	+8.21%
Mar 31, 2025	MORGAN STANLEY	0.02%	972	5.57K	0	0
Mar 31, 2025	COVESTOR LTD	0.02%	1.14K	7K	171	+17.65%
Mar 31, 2025	CITIGROUP INC	0%	0	-	-5.68K	-100.00%
Mar 31, 2025		0%	1	139	-19	-95.00%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0%	49	281	12	+32.43%
Mar 31, 2025	AIGH CAPITAL MANAGEMENT LLC	3.09%	196.35K	1.13M	75.05K	+61.87%
Mar 31, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	3.88%	246.08K	1.41M	15.01K	+6.50%
Mar 31, 2025	PERCEPTIVE ADVISORS LLC	4.37%	277.61K	1.59M	277.61K	+100.00%
Mar 31, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	4.71%	298.96K	1.71M	78.58K	+35.66%
Mar 31, 2025	SR ONE CAPITAL MANAGEMENT, LP	9.44%	598.94K	3.43M	0	0
Mar 31, 2025	CORMORANT ASSET MANAGEMENT, LP	9.5%	603.03K	3.46M	0	0
Mar 31, 2025	COMPAGNIE LOMBARD ODIER SCMA	0%	0	-	-400	-100.00%
Mar 31, 2025	PARALLEL ADVISORS, LLC	0%	1	6	0	0
Mar 31, 2025	NORTHERN TRUST CORP	0.16%	10.4K	59.59K	10.4K	+100.00%
Mar 31, 2025	BLACKROCK, INC.	0.34%	21.36K	122.37K	0	0
Mar 31, 2025	READYSTATE ASSET MANAGEMENT LP	0.67%	42.46K	243.29K	42.46K	+100.00%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.86%	54.83K	314.24K	7.19K	+15.09%
Mar 31, 2025	VANGUARD GROUP INC	2.41%	152.78K	875.4K	99.21K	+185.19%
Mar 31, 2025	WOODLINE PARTNERS LP	4.08%	258.77K	1.48M	258.77K	+100.00%
Mar 31, 2025	UBS OCONNOR LLC	2.69%	170.92K	979.35K	-8.02K	-4.48%
Mar 31, 2024	PARALLEL ADVISORS, LLC	0%	1	8	0	0
Dec 31, 2023	PARALLEL ADVISORS, LLC	0%	1	7	0	0
Sep 30, 2023	FIDUCIARY ALLIANCE LLC	0%	0	-	-95	-100.00%
Sep 30, 2023	WORTH ASSET MANAGEMENT, LLC	0%	0	-	-10	-100.00%
Sep 30, 2023	PARALLEL ADVISORS, LLC	0%	1	9	0	0

Insiders

Insiders	Designation	Shares Held
SHAH RAJEEV M.		7.04M
RA CAPITAL MANAGEMENT, L.P.	10 percent owner	7.04M
RA CAPITAL MANAGEMENT, LLC		4.54M
ORBIMED ADVISORS LLC	10 percent owner	3.45M
GRUNBERG GREGORY	director	2.53M
LONGITUDE CAPITAL PARTNERS II, LLC	10 percent owner	2.27M
CDK ASSOCIATES, L.L.C.	10 percent owner	215K
CHEN HONGMING	CHIEF SCIENTIFIC OFFICER	204.52K
IWICKI MARK T	director	103.54K
TRACHTENBERG ERIC	SEE REMARKS	68.07K
BAKER BROS. ADVISORS LP	Former 10% owner	46.48K
KHARABI DARIUS	CHIEF BUSINESS OFFICER	41.76K
BRAZZELL ROMULUS K	SEE REMARKS	35.95K
BAZEMORE TODD	director	35.93K
REUMUTH MARY	CHIEF FINANCIAL OFFICER	28.91K
ROSEN HOWARD B	director	8.24K

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Oct 23, 2025	REUMUTH MARY	SALE	0.82	967	792.94	28.91K
Oct 23, 2025	IWICKI MARK T	SALE	0.81	154.89K	125.46K	103.54K
Oct 22, 2025	BRAZZELL ROMULUS K	SALE	0.83	46.75K	38.8K	35.95K
Oct 22, 2025	KHARABI DARIUS	SALE	0.83	20.81K	17.27K	41.76K
Oct 22, 2025	BAZEMORE TODD	SALE	0.83	47.77K	39.65K	35.93K
Oct 22, 2025	REUMUTH MARY	SALE	0.83	32.23K	26.75K	29.87K
Oct 01, 2025	BAKER BROS. ADVISORS LP	SALE	1.38	50.64K	70.08K	46.48K
Sep 30, 2025	BAKER BROS. ADVISORS LP	SALE	1.60	21.38K	34.11K	97.12K
Jun 24, 2025	IWICKI MARK T	SALE	4.01	13.23K	53.04K	258.43K
Jun 24, 2025	KHARABI DARIUS	SALE	4.01	4.51K	18.09K	62.57K
Jun 24, 2025	REUMUTH MARY	SALE	4.01	3.63K	14.56K	62.1K
Jun 24, 2025	BAZEMORE TODD	SALE	4.01	4.06K	16.27K	83.7K
Jun 24, 2025	BRAZZELL ROMULUS K	SALE	4.01	5.25K	21.06K	82.7K
Jun 03, 2025	IWICKI MARK T	SALE	3.74	10.87K	40.64K	269.21K
Jun 03, 2025	KHARABI DARIUS	SALE	3.74	730	2.73K	67.08K
Jun 03, 2025	REUMUTH MARY	SALE	3.74	2.85K	10.66K	65.73K
Jun 03, 2025	BRAZZELL ROMULUS K	SALE	3.74	3.69K	13.79K	87.95K
Jun 03, 2025	BAZEMORE TODD	SALE	3.74	3.39K	12.68K	87.76K
Jan 06, 2025	IWICKI MARK T	SALE	7.63	5.78K	44.09K	280.08K
Jan 06, 2025	BAZEMORE TODD	SALE	7.63	1.99K	15.21K	0
Jan 06, 2025	KHARABI DARIUS	SALE	7.63	2.02K	15.42K	67.81K
Jan 06, 2025	REUMUTH MARY	SALE	7.63	1.71K	13.02K	68.58K
Jan 06, 2025	BRAZZELL ROMULUS K	SALE	7.63	2.45K	18.66K	92.42K
Dec 30, 2024	BAKER BROS. ADVISORS LP	PURCHASE	6.44	30.62K	197.19K	118.5K
Jun 26, 2024	KHARABI DARIUS	SALE	4.75	5.16K	24.5K	59.73K
Jun 26, 2024	BAZEMORE TODD	SALE	4.75	4.65K	22.1K	83.04K
Jun 26, 2024	IWICKI MARK T	SALE	4.75	15.17K	72.05K	263.76K
Jun 26, 2024	BRAZZELL ROMULUS K	SALE	4.75	5.49K	26.07K	83.98K
Jun 26, 2024	REUMUTH MARY	SALE	4.75	4.16K	19.77K	60.19K
May 31, 2024	REUMUTH MARY	SALE	6.09	1.79K	10.88K	64.35K
May 31, 2024	BAZEMORE TODD	SALE	6.09	2.09K	12.75K	87.69K
May 31, 2024	BRAZZELL ROMULUS K	SALE	6.09	2K	12.19K	89.47K
May 31, 2024	IWICKI MARK T	SALE	6.09	7.39K	45.02K	278.92K
May 31, 2024	KHARABI DARIUS	SALE	6.09	231	1.41K	64.89K
Jan 04, 2024	IWICKI MARK T	SALE	6.73	4.54K	30.55K	286.32K
Jan 04, 2024	REUMUTH MARY	SALE	6.74	1.23K	8.27K	66.14K
Jan 04, 2024	BAZEMORE TODD	SALE	6.74	1.41K	9.47K	0
Jan 04, 2024	TRACHTENBERG ERIC	SALE	6.74	1.23K	8.27K	68.07K
Jan 04, 2024	BRAZZELL ROMULUS K	SALE	6.74	1.62K	10.9K	91.47K
Jan 04, 2024	KHARABI DARIUS	SALE	6.73	1.39K	9.32K	65.12K
Jan 04, 2023	IWICKI MARK T	SALE	28.54	198	5.65K	45.97K
Jan 04, 2023	BRAZZELL ROMULUS K	SALE	28.53	73	2.08K	18.54K
Jan 04, 2023	TRACHTENBERG ERIC	SALE	28.55	60	1.71K	11.5K
Jan 04, 2023	REUMUTH MARY	SALE	28.54	60	1.71K	11.88K
Jan 04, 2023	BAZEMORE TODD	SALE	28.54	62	1.77K	14.84K
Oct 26, 2022	IWICKI MARK T	SALE	6.52	561	3.66K	4.46K
Oct 26, 2022	BRAZZELL ROMULUS K	SALE	6.51	261	1.7K	5.81K
Oct 26, 2022	REUMUTH MARY	SALE	6.51	194	1.26K	2.42K
Oct 26, 2022	TRACHTENBERG ERIC	SALE	6.52	194	1.26K	2.03K
Oct 26, 2022	BAZEMORE TODD	SALE	6.51	214	1.39K	2.1K
Jun 27, 2022	TRACHTENBERG ERIC	SALE	0.37	2.61K	966.81	111.2K
Jun 27, 2022	BAZEMORE TODD	SALE	0.37	3.09K	1.14K	115.5K
Jun 27, 2022	IWICKI MARK T	SALE	0.37	7.98K	2.95K	251.18K
Jun 27, 2022	BRAZZELL ROMULUS K	SALE	0.37	3.14K	1.16K	285.2K
Jun 27, 2022	REUMUTH MARY	SALE	0.37	2.61K	966.81	130.6K
May 26, 2022	RA CAPITAL MANAGEMENT, L.P.	SALE	0.36	1.01M	365.67K	7.04M
May 26, 2022	SHAH RAJEEV M.	SALE	0.36	1.01M	365.67K	7.04M
May 25, 2022	RA CAPITAL MANAGEMENT, L.P.	SALE	0.42	1.43M	602.49K	8.05M
May 24, 2022	RA CAPITAL MANAGEMENT, L.P.	SALE	0.51	144.81K	73.85K	9.48M
May 23, 2022	SHAH RAJEEV M.	SALE	0.65	1.25M	812.5K	9.62M
May 23, 2022	RA CAPITAL MANAGEMENT, L.P.	SALE	0.65	1.25M	812.5K	9.62M
Jan 04, 2022	REUMUTH MARY	SALE	1.30	2.85K	3.71K	133.21K
Jan 04, 2022	TRACHTENBERG ERIC	SALE	1.30	2.85K	3.71K	113.82K
Jan 04, 2022	IWICKI MARK T	SALE	1.30	9.52K	12.37K	259.16K
Jan 04, 2022	BRAZZELL ROMULUS K	SALE	1.30	3.5K	4.56K	288.35K
Jan 04, 2022	BAZEMORE TODD	SALE	1.30	3.45K	4.49K	118.59K
Oct 27, 2021	CHEN HONGMING	SALE	1.82	21.05K	38.31K	204.52K
Oct 26, 2021	BRAZZELL ROMULUS K	SALE	1.80	12.76K	22.96K	291.85K
Oct 26, 2021	REUMUTH MARY	SALE	1.80	9.45K	17.01K	136.06K
Oct 26, 2021	CHEN HONGMING	SALE	1.80	9.45K	17.01K	225.57K
Oct 26, 2021	TRACHTENBERG ERIC	SALE	1.80	9.45K	17.01K	116.67K
Oct 26, 2021	IWICKI MARK T	SALE	1.80	27.6K	49.68K	268.68K
Oct 26, 2021	BAZEMORE TODD	SALE	1.80	12.54K	22.58K	122.05K
Jun 29, 2021	CHEN HONGMING	SALE	5.56	5.55K	30.85K	235.02K
Jun 28, 2021	IWICKI MARK T	SALE	5.77	7.59K	43.77K	296.27K
Jun 28, 2021	BRAZZELL ROMULUS K	SALE	5.77	3.03K	17.51K	300.96K
Jun 28, 2021	TRACHTENBERG ERIC	SALE	5.77	2.45K	14.15K	126.12K
Jun 28, 2021	REUMUTH MARY	SALE	5.77	2.45K	14.15K	145.51K
Jun 28, 2021	CHEN HONGMING	SALE	5.77	2.45K	14.15K	240.56K
Jun 28, 2021	BAZEMORE TODD	SALE	5.77	2.91K	16.8K	0
Oct 22, 2020	BAZEMORE TODD	PURCHASE	7.60	40	304	42
Jun 05, 2020	BAZEMORE TODD	PURCHASE	13.39	2	26.78	2
Mar 16, 2020	BAZEMORE TODD	PURCHASE	5.75	10K	57.5K	10K
Mar 13, 2020	SHAH RAJEEV M.	PURCHASE	7.89	6.34M	50M	10.87M
Mar 13, 2020	RA CAPITAL MANAGEMENT, L.P.	PURCHASE	7.89	6.34M	50M	10.87M
Mar 13, 2020	GRUNBERG GREGORY	PURCHASE	7.89	2.53M	20M	2.53M
May 30, 2019	ROSEN HOWARD B	PURCHASE	5.42	5K	27.1K	8.24K
Oct 05, 2018	GRUNBERG GREGORY	PURCHASE	8.25	606.06K	5M	2.88M
Oct 03, 2018	SHAH RAJEEV M.	PURCHASE	8.25	2.42M	20M	4.54M
Oct 03, 2018	RA CAPITAL MANAGEMENT, LLC	PURCHASE	8.25	2.42M	20M	4.54M
Feb 08, 2018	ORBIMED ADVISORS LLC	PURCHASE	12.93	25K	323.25K	3.45M
Feb 02, 2018	ORBIMED ADVISORS LLC	PURCHASE	14.73	37.84K	557.38K	3.42M
Feb 01, 2018	ORBIMED ADVISORS LLC	PURCHASE	14.99	22.84K	342.37K	3.39M
Jan 31, 2018	ORBIMED ADVISORS LLC	PURCHASE	15.00	339.4K	5.09M	3.36M
Jan 29, 2018	ORBIMED ADVISORS LLC	PURCHASE	14.99	50K	749.5K	3.02M
Jan 26, 2018	ORBIMED ADVISORS LLC	PURCHASE	14.93	22.76K	339.81K	2.97M
Jan 24, 2018	ORBIMED ADVISORS LLC	PURCHASE	14.91	64.64K	963.74K	2.95M
Jan 23, 2018	ORBIMED ADVISORS LLC	PURCHASE	14.99	4.36K	65.4K	2.89M
Jan 22, 2018	ORBIMED ADVISORS LLC	PURCHASE	14.98	75K	1.12M	2.88M
Jan 19, 2018	ORBIMED ADVISORS LLC	PURCHASE	14.95	74.93K	1.12M	2.81M
Jan 12, 2018	ORBIMED ADVISORS LLC	PURCHASE	15.40	28.45K	438.07K	2.69M
Jan 11, 2018	ORBIMED ADVISORS LLC	PURCHASE	13.65	41.7K	569.21K	2.66M
Jan 10, 2018	ORBIMED ADVISORS LLC	PURCHASE	12.83	170.34K	2.19M	2.62M
Jul 25, 2017	GRUNBERG GREGORY	PURCHASE	15.00	215K	3.23M	2.27M
Jul 25, 2017	LONGITUDE CAPITAL PARTNERS II, LLC	PURCHASE	15.00	215K	3.23M	2.27M
Jul 25, 2017	ORBIMED ADVISORS LLC	PURCHASE	15.00	319.33K	4.79M	2.38M
Jul 25, 2017	RA CAPITAL MANAGEMENT, LLC	PURCHASE	15.00	533.33K	8M	2.11M
Jul 25, 2017	SHAH RAJEEV M.	PURCHASE	15.00	533.33K	8M	2.11M
Jul 20, 2017	CDK ASSOCIATES, L.L.C.	PURCHASE	15.00	215K	3.23M	215K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES375.43K8

NET SHARES-375.43K8

SHARES HELD419.56K8

% NET SHARES-189.48%0%

KALA Stock Ownership Breakdown

KALA BIO

Stock Outstanding Shares

Market Insider

Institutional Ownership

Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions

Stock Outstanding Shares

Market Insider

Institutional Ownership

Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions