How many institutions own INSM stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own INSM shares is 678, representing 101.27% of the company's common stock.

Who are the major shareholders selling Insmed Incorporated stock?

D. E. SHAW & CO., INC., in the last quarter, reduced its stake in INSM by -23.09% restricting it's holding to 4.35 million shares of worth nearly $757.25M. DUQUESNE FAMILY OFFICE LLC also lessened -38.86% of the INSM shares from its portfolio, reducing its holding to 1.48 million shares of worth $257.88M. GW&K INVESTMENT MANAGEMENT, LLC also shunned INSM shares holding by -19.8% last quarter which brought its holding to 482.67 thousand shares worth $84.01M.

Investors who are buying INSM stock?

As per its latest 13F filing, UBS GROUP AG increased its stake in INSM by 13.45% in the last quarter. The institutional holder raised its holding to 1.87 million shares having worth more than $325.04M. BNP PARIBAS ARBITRAGE, SNC also added 111.25% more shares of INSM to its portfolio, raising its holding to 915.42 thousand shares of worth $159.32M. GEODE CAPITAL MANAGEMENT, LLC also increased its INSM shares holding by 14.35% which brought its holding to 4.3 million shares worth $751.94M.

INSM's major insiders: who are they?

The insider with the most stakes in INSM is Lewis William , Chair and CEO at the company. Additionally, INSM stock is highly held by director SHAROKY MELVIN MD and Chief Commercial Officer Wise John Drayton among others.

Did an insider recently sell INSM stock?

Company executives, directors, and other insiders own 0.65% percent of Insmed Incorporated's stock. Within the last six months, there have been 41 transaction(s) in which INSM insiders have sold stock, totaling 120.22K shares. Insiders that have sold shares include LEWIS WILLIAM, SMITH MICHAEL ALEXANDER, and FLAMMER MARTINA M.D..

Which insider recently purchased INSM stock?

There have been 0 transaction(s) during the past 6-months in which Insmed Incorporated insiders have bought stock, totalling 0 shares

How much of INSM does insiders own?

Around 5.85M Insmed Incorporated shares are held by insiders, which represents about 0.65% of INSM stock.

Who is the insider with the largest stake?

INSM Chair and CEO, Lewis William holds the largest portfolio of the company's shares. INSM shares owned by Lewis total nearly 301.19 thousand.

Which institution holds the most shares in INSM?

UBS GROUP AG is the largest institutional owner in INSM which holds 1.87 million shares worth $325.04M or 0.88% of the total INSM shares outstanding followed by BNP PARIBAS ARBITRAGE, SNC with ownership of 915.42 thousand shares representing 0.43% of the INSM ownership. GEODE CAPITAL MANAGEMENT, LLC is the third largest stakeholder with 4.3 million shares or 2.03% of the ownership worth more than $751.94M.

Is Insmed Incorporated stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the INSM is concerned, it is a stock which is optionable.

Is there a short position on INSM's shares?

Number of INSM shares short is 9.54M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding INSM shares are there?

As of today, 211.38M shares of INSM are outstanding.

Is there many float in INSM stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, INSM has 190.42M shares in float.

INSM short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for INSM is 3.67.

Insmed (INSM) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares4.52

Short Percent Of Float5

Shares Outstanding211.38M

Shares Float190.42M

Shares Short9.54M

Short Ratio3.67

Short % of Float

4.52%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

0.65% Percentage of Shares held by All Insiders

101.27% Percentage of Shares held by All Institutions

101.93% Percentage of Float held by Institutions

678

Number of Institutions Holding Shares

Institutional Ownership

About 101.27% of INSM shares are held by financial institutions. UBS GROUP AG is the top corporate investor, holding 1.87M shares valued at $325.04M. A 0.88% stake in Insmed Incorporated is owned by the company. BNP PARIBAS ARBITRAGE, SNC owns 915.42K shares valued at $159.32M, which translates its holding of 0.43% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Dec 31, 2025	UBS GROUP AG	0.88%	1.87M	325.04M	221.4K	+13.45%
Dec 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.43%	915.42K	159.32M	482.08K	+111.25%
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.03%	4.3M	751.94M	539.63K	+14.35%
Dec 31, 2025	RTW INVESTMENTS, LP	2.29%	4.84M	842.85M	1.76M	+57.00%
Dec 31, 2025	D. E. SHAW & CO., INC.	2.05%	4.35M	757.25M	-1.31M	-23.09%
Dec 31, 2025	ORBIS ALLAN GRAY LTD	1.97%	4.18M	727.48M	929.09K	+28.58%
Dec 31, 2025	NORGES BANK	1.37%	2.91M	506.63M	2.91M	+100.00%
Dec 31, 2025	DUQUESNE FAMILY OFFICE LLC	0.7%	1.48M	257.88M	-941.68K	-38.86%
Dec 31, 2025	AQR CAPITAL MANAGEMENT LLC	0.22%	468.26K	81.5M	180.97K	+62.99%
Dec 31, 2025	CASTLE HOOK PARTNERS LP	0.59%	1.25M	218.17M	162.16K	+14.86%
Dec 31, 2025	SWISS NATIONAL BANK	0.27%	579.11K	100.79M	207.81K	+55.97%
Dec 31, 2025	WELLS FARGO & COMPANY/MN	0.28%	586.65K	102.1M	72.8K	+14.17%
Dec 31, 2025	DEUTSCHE BANK AG\	0.28%	590.03K	102.69M	385.68K	+188.73%
Dec 31, 2025	GW&K INVESTMENT MANAGEMENT, LLC	0.23%	482.67K	84.01M	-119.13K	-19.80%
Dec 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.4%	849.6K	147.86M	1.2K	+0.14%
Dec 31, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.45%	958.96K	167.26M	-181.86K	-15.94%
Dec 31, 2025	FIERA CAPITAL CORP	0.47%	992.89K	172.8M	183.77K	+22.71%
Dec 31, 2025	BANK OF NEW YORK MELLON CORP	0.66%	1.39M	241.92M	251.14K	+22.05%
Dec 31, 2025	EVENTIDE ASSET MANAGEMENT, LLC	0.23%	483.59K	84.16M	-521.52K	-51.89%
Dec 31, 2025	TIMESSQUARE CAPITAL MANAGEMENT, LLC	0.23%	490.51K	85.37M	65.42K	+15.39%
Dec 31, 2025	ROYAL BANK OF CANADA	0.24%	506.81K	88.21M	-848.52K	-62.61%
Dec 31, 2025	LEGAL & GENERAL GROUP PLC	0.26%	540.31K	94.04M	332.29K	+159.74%
Dec 31, 2025	JANE STREET GROUP, LLC	0.22%	463.6K	80.68B	-318.8K	-40.75%
Dec 31, 2025	JENNISON ASSOCIATES LLC	0.27%	562.3K	97.86M	-40.48K	-6.72%
Dec 31, 2025	MILLENNIUM MANAGEMENT LLC	0.62%	1.31M	228.28M	-1.02M	-43.85%
Dec 31, 2025	BANK OF AMERICA CORP /DE/	0.81%	1.73M	300.34M	123.88K	+7.73%
Dec 31, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.13%	276.28K	48.08M	-169.59K	-38.04%
Dec 31, 2025	NATIONAL PENSION SERVICE	0.13%	280.44K	48.81M	280.44K	+100.00%
Dec 31, 2025	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	0.16%	328.33K	57.16M	129.63K	+65.24%
Dec 31, 2025	PROSHARE ADVISORS LLC	0.16%	340.74K	59.3M	333.21K	+4,425.10%
Dec 31, 2025	FEDERATED HERMES, INC.	0.3%	632.3K	110.05M	304.08K	+92.64%
Dec 31, 2025	VICTORY CAPITAL MANAGEMENT INC	0.31%	646.71K	112.55M	291.81K	+82.22%
Dec 31, 2025	NUVEEN, LLC	0.31%	650.4K	113.2M	62.28K	+10.59%
Dec 31, 2025	LORD, ABBETT & CO. LLC	0.34%	720.9K	125.47M	-723.76K	-50.10%
Dec 31, 2025	MORGAN STANLEY	0.77%	1.63M	284.02M	668.28K	+69.35%
Dec 31, 2025	AMERIPRISE FINANCIAL INC	0.93%	1.97M	342.66M	-753.02K	-27.67%
Dec 31, 2025	INVESCO LTD.	1.29%	2.73M	474.58M	722.99K	+36.08%
Dec 31, 2025	FRANKLIN RESOURCES INC	1.3%	2.76M	479.57M	615.81K	+28.78%
Dec 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.91%	4.04M	703.03M	-2.89M	-41.72%
Dec 31, 2025	STATE STREET CORP	2.46%	5.2M	905.31M	1.22M	+30.55%
Dec 31, 2025	CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM	0.17%	354.91K	61.77M	44.02K	+14.16%
Dec 31, 2025	SEI INVESTMENTS CO	0.42%	890.17K	154.92M	296.29K	+49.89%
Dec 31, 2025	AFFINITY ASSET ADVISORS, LLC	0.21%	450K	78.32M	0	0
Dec 31, 2025	BARCLAYS PLC	0.21%	444.71K	77.4M	330.51K	+289.42%
Dec 31, 2025	SUMITOMO MITSUI TRUST HOLDINGS, INC.	0.21%	435.44K	75.78M	435.44K	+100.00%
Dec 31, 2025	CITADEL ADVISORS LLC	0.55%	1.16M	201.42M	-900.35K	-43.76%
Dec 31, 2025	VANGUARD GROUP INC	9.95%	21.08M	3.67B	1.14M	+5.72%
Dec 31, 2025	JEFFERIES FINANCIAL GROUP INC.	0.44%	926.34K	161.22M	818.24K	+756.95%
Dec 31, 2025	DARWIN GLOBAL MANAGEMENT, LTD.	9.89%	20.93M	3.64B	475.83K	+2.33%
Dec 31, 2025	FMR LLC	4.69%	9.93M	1.73B	746.97K	+8.14%
Dec 31, 2025	BAKER BROS. ADVISORS LP	3.11%	6.59M	1.15B	-110.74K	-1.65%
Dec 31, 2025	ARTISAN PARTNERS LIMITED PARTNERSHIP	2.29%	4.84M	843.01M	-93.93K	-1.90%
Dec 31, 2025	CAPITAL INTERNATIONAL INVESTORS	2.43%	5.15M	896.6M	-2.4M	-31.80%
Dec 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.49%	1.03M	178.8M	52.08K	+5.34%
Dec 31, 2025	GOLDMAN SACHS GROUP INC	0.59%	1.24M	216.63M	415.4K	+50.09%
Dec 31, 2025	JPMORGAN CHASE & CO	10.96%	23.2M	4.04B	151.84K	+0.66%
Dec 31, 2025	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.59%	1.25M	217.55M	-350K	-21.88%
Dec 31, 2025	NORTHERN TRUST CORP	0.58%	1.24M	215.54M	165.5K	+15.42%
Dec 31, 2025	WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC	0.58%	1.22M	212.52M	-333.96K	-21.48%
Dec 31, 2025	MACQUARIE MANAGEMENT HOLDINGS, INC.	0.56%	1.18M	205.89B	1.18M	+100.00%
Dec 31, 2025	NWI MANAGEMENT LP	0.47%	988.46K	172.03M	-32.54K	-3.19%
Dec 31, 2025	TWO SIGMA INVESTMENTS, LP	0.45%	962.16K	167.45M	189.38K	+24.51%
Dec 31, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.45%	943.31K	164.17M	430.56K	+83.97%
Dec 31, 2025	AMUNDI	0.43%	917K	159.59M	599.9K	+189.19%
Dec 31, 2025	SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC	0.43%	909.08K	158.22M	-132.77K	-12.74%
Dec 31, 2025	FIL LTD	0.4%	838.51K	145.93M	-13.45K	-1.58%
Dec 31, 2025	CLEARBRIDGE INVESTMENTS, LLC	0.39%	819.01K	142.54M	-249.01K	-23.31%
Dec 31, 2025	HOLOCENE ADVISORS, LP	0.38%	801.17K	139.43M	-282.52K	-26.07%
Dec 31, 2025	JANUS HENDERSON GROUP PLC	0.38%	800.56K	139.33M	-402.23K	-33.44%
Dec 31, 2025	RAYMOND JAMES FINANCIAL INC	0.37%	779.25K	135.65M	19.28K	+2.54%
Dec 31, 2025	PRINCIPAL FINANCIAL GROUP INC	0.36%	771.36K	134.25M	-92.94K	-10.75%
Dec 31, 2025	BLACKROCK, INC.	7.11%	15.07M	2.62B	2.7M	+21.84%
Dec 31, 2025	WESTFIELD CAPITAL MANAGEMENT CO LP	0.2%	432.52K	75.28M	-55.41K	-11.36%
Dec 31, 2025	CANDRIAM S.C.A.	0.19%	401.04K	69.8M	3.45K	+0.87%
Dec 31, 2025	DIMENSIONAL FUND ADVISORS LP	0.19%	399.07K	69.46M	12.4K	+3.21%
Dec 31, 2025	MARSHALL WACE, LLP	0.18%	389.88K	67.85M	-268.77K	-40.81%
Dec 31, 2025	ENSIGN PEAK ADVISORS, INC	0.18%	382.2K	66.52M	-259.83K	-40.47%
Dec 31, 2025	GATEWAY INVESTMENT ADVISERS LLC	0.17%	365K	63.52M	365K	+100.00%
Dec 31, 2025	SAMLYN CAPITAL, LLC	0.17%	369.58K	64.32M	76.93K	+26.29%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0.27%	513.85K	74M	254.64K	+98.24%
Sep 30, 2025	NUVEEN, LLC	0.31%	588.12K	84.7M	-865	-0.15%
Sep 30, 2025	ROYAL BANK OF CANADA	0.64%	1.36M	195.18M	927.53K	+216.81%
Sep 30, 2025	FIERA CAPITAL CORP	0.38%	809.12K	116.52M	61.08K	+8.17%
Sep 30, 2025	FMR LLC	4.34%	9.18M	1.32B	4.09M	+80.26%
Sep 30, 2025	D. E. SHAW & CO., INC.	2.67%	5.66M	814.73M	2.23M	+65.30%
Sep 30, 2025	ARTISAN PARTNERS LIMITED PARTNERSHIP	2.33%	4.94M	711.08M	1.62M	+48.98%
Sep 30, 2025	DUQUESNE FAMILY OFFICE LLC	1.14%	2.42M	349M	170K	+7.54%
Sep 30, 2025	LORD, ABBETT & CO. LLC	0.68%	1.44M	208.05M	-101.2K	-6.55%
Sep 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.59%	1.25M	180.37M	-1.61M	-56.20%
Sep 30, 2025	JANUS HENDERSON GROUP PLC	0.57%	1.2M	173.21M	-1.09M	-47.55%
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.54%	1.14M	164.01M	-58.57K	-4.89%
Sep 30, 2025	TWO SIGMA INVESTMENTS, LP	0.41%	772.78K	111.29M	396.27K	+105.25%
Sep 30, 2025	STATE STREET CORP	1.88%	3.98M	573.79M	-293.53K	-6.86%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.78%	3.76M	541.5M	418.72K	+12.53%
Sep 30, 2025	ORBIS ALLAN GRAY LTD	1.54%	3.25M	468.16M	1.73M	+113.29%
Sep 30, 2025	MILLENNIUM MANAGEMENT LLC	1.1%	2.34M	336.42M	214.4K	+10.10%
Sep 30, 2025	JPMORGAN CHASE & CO	12.18%	23.05M	3.32B	7.41M	+47.40%
Sep 30, 2025	VANGUARD GROUP INC	9.41%	19.94M	2.87B	2.29M	+12.99%
Sep 30, 2025	ENSIGN PEAK ADVISORS, INC	0.34%	642.03K	92.46M	77.65K	+13.76%
Sep 30, 2025	JENNISON ASSOCIATES LLC	0.32%	602.78K	86.81M	-112.83K	-15.77%
Sep 30, 2025	GW&K INVESTMENT MANAGEMENT, LLC	0.32%	601.8K	86.67M	-672.51K	-52.77%
Sep 30, 2025	SEI INVESTMENTS CO	0.31%	593.89K	85.53M	160.26K	+36.96%
Sep 30, 2025	ALLIANCEBERNSTEIN L.P.	0.41%	868.77K	125.11M	-474.44K	-35.32%
Sep 30, 2025	HOOD RIVER CAPITAL MANAGEMENT LLC	0.42%	881.4K	126.93M	-18.2K	-2.02%
Sep 30, 2025	MORGAN STANLEY	0.46%	963.63K	138.77M	-80.16K	-7.68%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.46%	975.28K	140.45M	-324.29K	-24.95%
Sep 30, 2025	PRINCIPAL FINANCIAL GROUP INC	0.41%	864.29K	124.47M	-483.73K	-35.88%
Sep 30, 2025	MACQUARIE GROUP LTD	0.34%	649.85K	93.58M	-481.08K	-42.54%
Sep 30, 2025	MAVERICK CAPITAL LTD	0.35%	656.54K	94.55M	-147.59K	-18.35%
Sep 30, 2025	MARSHALL WACE, LLP	0.35%	658.65K	94.85M	-454.71K	-40.84%
Sep 30, 2025	PERCEPTIVE ADVISORS LLC	0.37%	702.13K	101.11M	51.88K	+7.98%
Sep 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.38%	718.04K	103.41M	-441.66K	-38.08%
Sep 30, 2025	ARTIA GLOBAL PARTNERS LP	0.39%	732.21K	105.45M	-20.5K	-2.72%
Sep 30, 2025	RAYMOND JAMES FINANCIAL INC	0.4%	759.98K	109.44M	-24.57K	-3.13%
Sep 30, 2025	DARWIN GLOBAL MANAGEMENT, LTD.	9.66%	20.46M	2.9B	1.11M	+5.75%
Sep 30, 2025	FIL LTD	0.4%	851.95K	122.69M	-313.51K	-26.90%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.85%	1.6M	230.68M	375.07K	+30.57%
Sep 30, 2025	JANE STREET GROUP, LLC	0.37%	782.4K	112.67M	44.6K	+6.05%
Sep 30, 2025	CLEARBRIDGE INVESTMENTS, LLC	0.5%	1.07M	153.81M	-356.54K	-25.03%
Sep 30, 2025	NORTHERN TRUST CORP	0.51%	1.07M	154.51M	103.14K	+10.64%
Sep 30, 2025	HOLOCENE ADVISORS, LP	0.51%	1.08M	156.06M	-933.13K	-46.27%
Sep 30, 2025	CASTLE HOOK PARTNERS LP	0.52%	1.09M	157.17M	638.75K	+141.11%
Sep 30, 2025	WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC	0.73%	1.56M	223.94M	-110.55K	-6.64%
Sep 30, 2025	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.76%	1.6M	230.42M	0	0
Sep 30, 2025	UBS GROUP AG	0.78%	1.65M	237.07M	1.35M	+460.99%
Sep 30, 2025	INVESCO LTD.	0.95%	2M	288.58M	107.54K	+5.67%
Sep 30, 2025	CITADEL ADVISORS LLC	0.97%	2.06M	296.32M	524.36K	+34.20%
Sep 30, 2025	FRANKLIN RESOURCES INC	1.01%	2.14M	308.14M	-210.41K	-8.95%
Sep 30, 2025	BLACKROCK, INC.	5.84%	12.36M	1.78B	1.22M	+10.97%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	0.39%	829.32K	119.43M	-981.58K	-54.20%
Sep 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.4%	848.4K	122.18M	-153.2K	-15.30%
Sep 30, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.73%	1.54M	222.4M	462.27K	+42.72%
Sep 30, 2025	BAKER BROS. ADVISORS LP	3.17%	6.7M	965.37M	-1.01M	-13.09%
Sep 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	3.27%	6.93M	998.2M	-4.3M	-38.28%
Sep 30, 2025	AMERIPRISE FINANCIAL INC	1.29%	2.72M	391.98M	-236.09K	-7.98%
Sep 30, 2025	RTW INVESTMENTS, LP	1.46%	3.08M	444.21M	0	0
Sep 30, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.11%	206.65K	29.76M	-42.41K	-17.03%
Sep 30, 2025	LEGAL & GENERAL GROUP PLC	0.11%	208.02K	29.96M	170	+0.08%
Sep 30, 2025	RHUMBLINE ADVISERS	0.11%	212.9K	30.66M	4.56K	+2.19%
Sep 30, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.12%	219.84K	31.66M	-187.84K	-46.08%
Sep 30, 2025	ALLSPRING GLOBAL INVESTMENTS HOLDINGS, LLC	0.12%	227.63K	33.53M	-76.68K	-25.20%
Sep 30, 2025	ABRDN PLC	0.12%	234.62K	33.79M	-75.13K	-24.25%
Sep 30, 2025	FIRST TRUST ADVISORS LP	0.13%	240.65K	34.66M	193.25K	+407.78%
Sep 30, 2025	EAGLE HEALTH INVESTMENTS LP	0.14%	271.6K	39.11M	-157K	-36.63%
Sep 30, 2025	PATIENT SQUARE CAPITAL LP	0.17%	326.4K	47M	-32.4K	-9.03%
Sep 30, 2025	FEDERATED HERMES, INC.	0.17%	328.22K	47.27M	219.84K	+202.83%
Sep 30, 2025	ENVESTNET ASSET MANAGEMENT INC	0.18%	342.79K	49.36M	-23.04K	-6.30%
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.19%	352.89K	50.82M	44.2K	+14.32%
Sep 30, 2025	VICTORY CAPITAL MANAGEMENT INC	0.19%	354.91K	51.11M	172.13K	+94.18%
Sep 30, 2025	SWISS NATIONAL BANK	0.2%	371.3K	53.47M	23.9K	+6.88%
Sep 30, 2025	ING GROEP NV	0.2%	373.5K	53.79M	373.5K	+100.00%
Sep 30, 2025	DIMENSIONAL FUND ADVISORS LP	0.2%	386.67K	55.67M	-25.07K	-6.09%
Sep 30, 2025	CANDRIAM S.C.A.	0.21%	397.59K	57.26M	-41.1K	-9.37%
Sep 30, 2025	TD ASSET MANAGEMENT INC	0.21%	398.26K	57.35M	3.06K	+0.77%
Sep 30, 2025	TIMESSQUARE CAPITAL MANAGEMENT, LLC	0.22%	425.09K	61.22M	-448.41K	-51.33%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.23%	433.34K	62.41M	-320.82K	-42.54%
Sep 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.24%	445.88K	64.21M	18.12K	+4.24%
Sep 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.24%	450K	64.8M	-25K	-5.26%
Sep 30, 2025	WESTFIELD CAPITAL MANAGEMENT CO LP	0.26%	487.93K	70.27M	-851.36K	-63.57%
Sep 30, 2025	LOOMIS SAYLES & CO L P	0.26%	492.3K	70.9M	-301.27K	-37.96%
Sep 30, 2025	NWI MANAGEMENT LP	0.54%	1.02M	147.03M	301K	+41.81%
Sep 30, 2025	CAPITAL INTERNATIONAL INVESTORS	3.57%	7.55M	1.09B	74.99K	+1.00%
Sep 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.54%	1.14M	163.94M	-412.8K	-26.57%
Sep 30, 2025	SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC	0.49%	1.04M	150.04M	32.91K	+3.26%
Sep 30, 2025	EVENTIDE ASSET MANAGEMENT, LLC	0.47%	1.01M	144.74M	-191.39K	-16.00%
Jun 30, 2025	AMERIPRISE FINANCIAL INC	1.56%	2.96M	297.69M	6.35K	+0.22%
Jun 30, 2025	MILLENNIUM MANAGEMENT LLC	1.12%	2.12M	213.53M	1.44M	+212.39%
Jun 30, 2025	WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC	0.88%	1.67M	167.63M	-647.62K	-28.00%
Jun 30, 2025	PRINCIPAL FINANCIAL GROUP INC	0.71%	1.35M	135.67M	-407.35K	-23.21%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0.65%	1.23M	123.46M	-126.26K	-9.33%
Jun 30, 2025	NORGES BANK	1.02%	1.93M	194.73M	1.93M	+100.00%
Jun 30, 2025		0.31%	588.99K	59.28M	-569.11K	-49.14%
Jun 30, 2025	ALYESKA INVESTMENT GROUP, L.P.	0.32%	603.7K	60.76M	-131.3K	-17.86%
Jun 30, 2025	LORD, ABBETT & CO. LLC	0.82%	1.55M	155.58M	195.27K	+14.46%
Jun 30, 2025	PERCEPTIVE ADVISORS LLC	0.34%	650.25K	65.44M	140.95K	+27.68%
Jun 30, 2025	NOVO HOLDINGS A/S	0.36%	680K	68.44M	-44.67K	-6.16%
Jun 30, 2025	POLAR CAPITAL HOLDINGS PLC	0.37%	697.96K	70.24M	-30.8K	-4.23%
Jun 30, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	0.37%	700.7K	70.52M	242.7K	+52.99%
Jun 30, 2025	FIERA CAPITAL CORP	0.4%	748.04K	75.28M	168.8K	+29.14%
Jun 30, 2025	ARTIA GLOBAL PARTNERS LP	0.4%	752.71K	75.75M	434.47K	+136.52%
Jun 30, 2025	MAVERICK CAPITAL LTD	0.42%	804.13K	80.93M	379.01K	+89.15%
Jun 30, 2025	SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC	0.53%	1.01M	101.54M	304.57K	+43.24%
Jun 30, 2025	FIL LTD	0.62%	1.17M	117.29M	-1.22M	-51.24%
Jun 30, 2025	EVENTIDE ASSET MANAGEMENT, LLC	0.63%	1.2M	120.41M	14.82K	+1.25%
Jun 30, 2025	ARTISAN PARTNERS LIMITED PARTNERSHIP	1.75%	3.31M	333.56M	97.07K	+3.02%
Jun 30, 2025	D. E. SHAW & CO., INC.	1.81%	3.42M	344.45B	2.69M	+365.74%
Jun 30, 2025	ORBIS ALLAN GRAY LTD	0.81%	1.52M	153.39M	1.52M	+100.00%
Jun 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.82%	1.55M	156.19M	-459.7K	-22.83%
Jun 30, 2025	INVESCO LTD.	1%	1.9M	190.85M	105.01K	+5.86%
Jun 30, 2025	FRANKLIN RESOURCES INC	1.24%	2.35M	236.52M	201.85K	+9.40%
Jun 30, 2025	MACQUARIE GROUP LTD	0.6%	1.13M	113.82M	-1.23M	-52.12%
Jun 30, 2025	JANE STREET GROUP, LLC	0.71%	1.35M	136.16M	1.23M	+985.93%
Jun 30, 2025	CLEARBRIDGE INVESTMENTS, LLC	0.75%	1.42M	143.37M	-404.17K	-22.10%
Jun 30, 2025	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.85%	1.6M	161.02M	50K	+3.23%
Jun 30, 2025	JANUS HENDERSON GROUP PLC	1.21%	2.29M	230.78M	747.72K	+48.38%
Jun 30, 2025	STATE STREET CORP	2.26%	4.28M	430.53M	-1.47M	-25.57%
Jun 30, 2025	WESTFIELD CAPITAL MANAGEMENT CO LP	0.71%	1.34M	134.79M	-67.32K	-4.79%
Jun 30, 2025	TIMESSQUARE CAPITAL MANAGEMENT, LLC	0.46%	873.49K	87.91M	-190.66K	-17.92%
Jun 30, 2025	GW&K INVESTMENT MANAGEMENT, LLC	0.67%	1.27M	128.25M	-103.41K	-7.51%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.69%	1.3M	130.79M	-303.09K	-18.91%
Jun 30, 2025	MORGAN STANLEY	0.55%	1.04M	105.05B	-15.87K	-1.50%
Jun 30, 2025	ALLIANCEBERNSTEIN L.P.	0.71%	1.34M	135.18B	-1.08M	-44.58%
Jun 30, 2025	CITADEL ADVISORS LLC	0.81%	1.53M	154.31B	1.16M	+309.08%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.96%	1.81M	182.25B	408.27K	+29.11%
Jun 30, 2025	JPMORGAN CHASE & CO	8.26%	15.64M	1.57B	9.28M	+146.09%
Jun 30, 2025	VANGUARD GROUP INC	9.32%	17.64M	1.78B	-623.63K	-3.41%
Jun 30, 2025	HOOD RIVER CAPITAL MANAGEMENT LLC	0.48%	899.6K	90.54M	-658.68K	-42.27%
Jun 30, 2025	NORTHERN TRUST CORP	0.51%	969.8K	97.6M	-714.04K	-42.41%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.53%	1M	100.8M	665.6K	+198.10%
Jun 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.25%	475K	47.8M	335K	+239.29%
Jun 30, 2025	HOLOCENE ADVISORS, LP	1.07%	2.02M	202.97M	-9.62K	-0.47%
Jun 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	1.51%	2.86M	287.78M	-587.49K	-17.04%
Jun 30, 2025	FMR LLC	2.69%	5.09M	512.59M	1.7M	+50.05%
Jun 30, 2025	LOOMIS SAYLES & CO L P	0.42%	793.57K	79.86M	-215.9K	-21.39%
Jun 30, 2025	CANDRIAM S.C.A.	0.23%	438.69K	44.15M	-16.72K	-3.67%
Jun 30, 2025	CASTLE HOOK PARTNERS LP	0.24%	452.66K	45.56M	452.66K	+100.00%
Jun 30, 2025	BAKER BROS. ADVISORS LP	4.07%	7.71M	776.23M	2.33M	+43.35%
Jun 30, 2025	DARWIN GLOBAL MANAGEMENT, LTD.	10.22%	19.34M	1.92B	3.95M	+25.63%
Jun 30, 2025	PALO ALTO INVESTORS LP	0.46%	865.11K	87.06M	-122.04K	-12.36%
Jun 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.61%	1.16M	116.71M	-62.93K	-5.15%
Jun 30, 2025	BANK OF NEW YORK MELLON CORP	0.63%	1.2M	120.51M	40.72K	+3.52%
Jun 30, 2025	DEEP TRACK CAPITAL, LP	0.92%	1.75M	176.12M	1.5M	+586.95%
Jun 30, 2025	MARSHALL WACE, LLP	0.59%	1.11M	112.05M	417.12K	+59.91%
Jun 30, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.57%	1.08M	108.9M	1.08M	+100.00%
Jun 30, 2025	BLACKROCK, INC.	5.89%	11.14M	1.12B	-4.91M	-30.57%
Jun 30, 2025	WEISS ASSET MANAGEMENT LP	0.18%	339.83K	34.2M	339.83K	+100.00%
Jun 30, 2025	CAPTION MANAGEMENT, LLC	0.15%	282.1K	28.39M	134.3K	+90.87%
Jun 30, 2025	LOS ANGELES CAPITAL MANAGEMENT LLC	0.17%	330.8K	33.29M	318.72K	+2,637.50%
Jun 30, 2025	SOFINNOVA INVESTMENTS, INC.	0.17%	313.92K	31.59M	9.67K	+3.18%
Jun 30, 2025	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.17%	313.05K	31.51M	310.38K	+11,594.17%
Jun 30, 2025	ABRDN PLC	0.16%	309.75K	31.17M	-26.61K	-7.91%
Jun 30, 2025	HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND	0.13%	250.1K	25.17M	250.1K	+100.00%
Jun 30, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.13%	249.06K	25.07M	-72.31K	-22.50%
Jun 30, 2025	SUVRETTA CAPITAL MANAGEMENT, LLC	0.13%	238.78K	24.03M	-1.25M	-84.00%
Jun 30, 2025	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.12%	226.14K	22.76M	211K	+1,393.38%
Jun 30, 2025	Y-INTERCEPT (HONG KONG) LTD	0.12%	224.3K	22.57M	224.3K	+100.00%
Jun 30, 2025	RAYMOND JAMES FINANCIAL INC	0.41%	784.55K	78.96M	375.61K	+91.85%
Jun 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.4%	754.16K	75.9B	292.5K	+63.36%
Jun 30, 2025	HRT FINANCIAL LP	0.39%	729.6K	73.43M	729.6K	+100.00%
Jun 30, 2025	NWI MANAGEMENT LP	0.38%	720K	72.46M	270K	+60.00%
Jun 30, 2025	JENNISON ASSOCIATES LLC	0.38%	715.61K	72.02M	-32.71K	-4.37%
Jun 30, 2025	ENSIGN PEAK ADVISORS, INC	0.3%	564.39K	56.8M	-25.01K	-4.24%
Jun 30, 2025	CORMORANT ASSET MANAGEMENT, LP	0.29%	540K	54.35M	15K	+2.86%
Jun 30, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	0.28%	525K	52.84M	9.1K	+1.76%
Jun 30, 2025	LONG FOCUS CAPITAL MANAGEMENT, LLC	0.27%	520.2K	52.35M	-110.6K	-17.53%
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	5.93%	11.23M	1.13B	-1.69M	-13.10%
Jun 30, 2025	CAPITAL INTERNATIONAL INVESTORS	3.95%	7.48M	752.67M	280.37K	+3.89%
Jun 30, 2025	RTW INVESTMENTS, LP	1.63%	3.08M	310.43M	70K	+2.32%
Jun 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.26%	490.67K	49.38M	490.67K	+100.00%
Jun 30, 2025	ALKEON CAPITAL MANAGEMENT LLC	0.26%	500K	50.32M	500K	+100.00%
Jun 30, 2025	BROWN ADVISORY INC	0.31%	579.85K	58.36M	-92.6K	-13.77%
Jun 30, 2025	DUQUESNE FAMILY OFFICE LLC	1.19%	2.25M	226.79M	884.39K	+64.60%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.76%	3.34M	336.26M	-948.03K	-22.11%
Mar 31, 2025	EVENTIDE ASSET MANAGEMENT, LLC	0.65%	1.18M	90.16M	80.68K	+7.33%
Mar 31, 2025	HOLOCENE ADVISORS, LP	1.12%	2.03M	154.6M	1.34M	+194.66%
Mar 31, 2025	AMERIPRISE FINANCIAL INC	1.63%	2.95M	225.17M	101.53K	+3.56%
Mar 31, 2025	FIL LTD	1.32%	2.39M	182.35M	-247.96K	-9.40%
Mar 31, 2025	ALLIANCEBERNSTEIN L.P.	1.34%	2.42M	184.89M	59.95K	+2.54%
Mar 31, 2025	DUQUESNE FAMILY OFFICE LLC	0.76%	1.37M	104.45M	775.58K	+130.69%
Mar 31, 2025	MORGAN STANLEY	0.59%	1.06M	80.84M	-291.71K	-21.59%
Mar 31, 2025	LOOMIS SAYLES & CO L P	0.56%	1.01M	77.01M	-165.33K	-14.07%
Mar 31, 2025	PALO ALTO INVESTORS LP	0.55%	987.15K	75.31M	-616.31K	-38.44%
Mar 31, 2025	JANE STREET GROUP, LLC	0.41%	742K	56.61M	7.5K	+1.02%
Mar 31, 2025	ALYESKA INVESTMENT GROUP, L.P.	0.41%	735K	56.07M	-200.78K	-21.46%
Mar 31, 2025	CLEARBRIDGE INVESTMENTS, LLC	1.01%	1.83M	139.51M	-49.72K	-2.65%
Mar 31, 2025	INVESCO LTD.	0.99%	1.79M	136.66M	775.23K	+76.30%
Mar 31, 2025	CAPITAL INTERNATIONAL INVESTORS	3.98%	7.2M	549.17M	81.49K	+1.15%
Mar 31, 2025	MACQUARIE GROUP LTD	1.31%	2.36M	180.21B	48.95K	+2.12%
Mar 31, 2025	WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC	1.28%	2.31M	176.48M	-120.23K	-4.94%
Mar 31, 2025	VANGUARD GROUP INC	10.1%	18.27M	1.39B	49.15K	+0.27%
Mar 31, 2025	PRINCIPAL FINANCIAL GROUP INC	0.97%	1.76M	133.92M	-62.27K	-3.43%
Mar 31, 2025	PICTET ASSET MANAGEMENT HOLDING SA	1.11%	2.01M	153.85M	53.61K	+2.74%
Mar 31, 2025	NORTHERN TRUST CORP	0.93%	1.68M	128.46M	-66.8K	-3.82%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.89%	1.6M	122.27M	56.05K	+3.62%
Mar 31, 2025	JANUS HENDERSON GROUP PLC	0.85%	1.55M	120.53M	99.72K	+6.90%
Mar 31, 2025	SUVRETTA CAPITAL MANAGEMENT, LLC	0.83%	1.49M	113.85M	-119.18K	-7.40%
Mar 31, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	0.82%	1.48M	112.68M	-505.76K	-25.51%
Mar 31, 2025	WESTFIELD CAPITAL MANAGEMENT CO LP	0.78%	1.41M	107.31M	468.06K	+49.87%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.78%	1.4M	107.01M	-317.43K	-18.45%
Mar 31, 2025	GW&K INVESTMENT MANAGEMENT, LLC	0.76%	1.38M	105.11M	242.33K	+21.34%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0.75%	1.35M	103.22M	245.33K	+22.15%
Mar 31, 2025	HOOD RIVER CAPITAL MANAGEMENT LLC	0.86%	1.56M	118.88M	32.66K	+2.14%
Mar 31, 2025	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.86%	1.55M	118.25M	0	0
Mar 31, 2025	BLACKROCK, INC.	8.87%	16.05M	1.22B	15.94K	+0.10%
Mar 31, 2025	DARWIN GLOBAL MANAGEMENT, LTD.	8.51%	15.4M	1.2B	2.44M	+18.81%
Mar 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	7.15%	12.92M	985.94M	219.13K	+1.72%
Mar 31, 2025	LORD, ABBETT & CO. LLC	0.75%	1.35M	103.04M	-106.62K	-7.32%
Mar 31, 2025	JPMORGAN CHASE & CO	3.51%	6.35M	484.75M	3.07M	+93.35%
Mar 31, 2025	STATE STREET CORP	3.18%	5.75M	438.46M	-358.86K	-5.88%
Mar 31, 2025	BAKER BROS. ADVISORS LP	2.98%	5.38M	410.49M	373.76K	+7.47%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.37%	4.29M	327.26M	201.59K	+4.93%
Mar 31, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	1.91%	3.45M	262.97M	1.8M	+109.21%
Mar 31, 2025	FMR LLC	1.88%	3.39M	258.96M	-1.46M	-30.10%
Mar 31, 2025	ARTISAN PARTNERS LIMITED PARTNERSHIP	1.78%	3.22M	245.45M	90.93K	+2.91%
Mar 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.68%	1.22M	93.27M	470.4K	+62.53%
Mar 31, 2025	FRANKLIN RESOURCES INC	1.19%	2.15M	163.89M	-11.82K	-0.55%
Mar 31, 2025		0.64%	1.16M	88.35M	1.16M	+100.00%
Mar 31, 2025	BANK OF NEW YORK MELLON CORP	0.64%	1.16M	88.25M	-281.72K	-19.58%
Mar 31, 2025	VESTAL POINT CAPITAL, LP	0.59%	1.08M	82.01M	175K	+19.44%
Mar 31, 2025	TIMESSQUARE CAPITAL MANAGEMENT, LLC	0.59%	1.06M	81.18M	379.76K	+55.49%
Mar 31, 2025	AMERICAN CENTURY COMPANIES INC	0.48%	872.12K	66.53M	59.34K	+7.30%
Mar 31, 2025	JENNISON ASSOCIATES LLC	0.41%	748.31K	57.09M	-25.5K	-3.30%
Mar 31, 2025	RTW INVESTMENTS, LP	1.67%	3.01M	229.98M	0	0
Mar 31, 2024	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	2.38%	3.45M	93.64M	-2.4M	-41.00%
Mar 31, 2024	FRANKLIN RESOURCES INC	2.46%	3.57M	96.77M	170.29K	+5.01%
Mar 31, 2024	MACQUARIE GROUP LTD	2.69%	3.9M	105.79M	-751.99K	-16.17%
Mar 31, 2024	WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC	2.91%	4.21M	114.35M	-41.97K	-0.99%
Mar 31, 2024	FMR LLC	6.44%	9.32M	252.82M	4.23M	+83.02%
Mar 31, 2024	BLACKROCK INC.	8.15%	11.8M	320.13M	307.42K	+2.68%
Mar 31, 2024	VANGUARD GROUP INC	10.02%	14.51M	393.64M	383.71K	+2.72%
Mar 31, 2024	GREAT POINT PARTNERS LLC	0.54%	775.59K	21.04M	549.67K	+243.31%
Mar 31, 2024	PICTET ASSET MANAGEMENT HOLDING SA	1.06%	1.53M	41.51M	-431.79K	-22.01%
Mar 31, 2024	CAPITAL INTERNATIONAL INVESTORS	1.12%	1.62M	43.97M	1.62M	+100.00%
Mar 31, 2024	RTW INVESTMENTS, LP	1.29%	1.87M	50.6M	0	0
Mar 31, 2024	SUVRETTA CAPITAL MANAGEMENT, LLC	1.4%	2.02M	54.88M	-661.49K	-24.64%
Mar 31, 2024	CAPTION MANAGEMENT, LLC	0.42%	609.7K	16.54M	595.6K	+4,224.11%
Mar 31, 2024	HUDSON BAY CAPITAL MANAGEMENT LP	0.43%	626.81K	17.01M	159.31K	+34.08%
Mar 31, 2024	EMERALD ADVISERS, LLC	0.44%	630.18K	17.1M	-300.67K	-32.30%
Mar 31, 2024	EVENTIDE ASSET MANAGEMENT, LLC	0.44%	635.19K	17.23M	0	0
Mar 31, 2024	AMERICAN CENTURY COMPANIES INC	0.49%	702.62K	19.06M	40.42K	+6.10%
Mar 31, 2024	TWO SIGMA ADVISERS, LP	0.49%	716.4K	19.44M	87.2K	+13.86%
Mar 31, 2024	FIL LTD	0.5%	720.25K	19.54M	28.81K	+4.17%
Mar 31, 2024	FRONTIER CAPITAL MANAGEMENT CO LLC	0.52%	747.33K	20.28M	747.33K	+100.00%
Mar 31, 2024	VESTAL POINT CAPITAL, LP	0.52%	750K	20.35M	-150K	-16.67%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.52%	753.61K	20.45M	-8.16K	-1.07%
Mar 31, 2024	CITADEL ADVISORS LLC	0.64%	927.56K	25.16M	-118.65K	-11.34%
Mar 31, 2024	CLEARBRIDGE INVESTMENTS, LLC	0.64%	930.41K	25.24M	930.41K	+100.00%
Mar 31, 2024	MORGAN STANLEY	0.65%	939.6K	25.49M	-595.14K	-38.78%
Mar 31, 2024	HOOD RIVER CAPITAL MANAGEMENT LLC	0.66%	962.5K	26.11M	56.68K	+6.26%
Mar 31, 2024	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	0.67%	972.31K	26.38M	76.37K	+8.52%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.69%	996.13K	27.02M	-47.7K	-4.57%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.78%	1.13M	30.57M	-1.67K	-0.15%
Mar 31, 2024	ASSENAGON ASSET MANAGEMENT S.A.	0.84%	1.21M	32.87M	927.04K	+325.83%
Mar 31, 2024	GW&K INVESTMENT MANAGEMENT, LLC	0.88%	1.27M	34.45M	-21.87K	-1.69%
Mar 31, 2024	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.9%	1.3M	35.27M	950K	+271.43%
Mar 31, 2024	MARSHALL WACE, LLP	0.92%	1.33M	36.08M	-109.72K	-7.62%
Mar 31, 2024	NORTHERN TRUST CORP	0.92%	1.34M	36.27M	-35.45K	-2.58%
Mar 31, 2024	NOVO HOLDINGS A/S	0.92%	1.34M	36.34M	0	0
Mar 31, 2024	FIRST TRUST ADVISORS LP	0.99%	1.44M	38.99M	1.34M	+1,398.12%
Mar 31, 2024	PRINCIPAL FINANCIAL GROUP INC	0.99%	1.44M	39.05M	79.72K	+5.86%
Mar 31, 2024	LOOMIS SAYLES & CO L P	1.03%	1.49M	40.47M	-839.71K	-36.02%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	1.42%	2.05M	55.65M	-305.55K	-12.96%
Mar 31, 2024	BELLEVUE GROUP AG	1.48%	2.14M	58.11M	-149.12K	-6.51%
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	1.48%	2.15M	58.23M	-1.42K	-0.07%
Mar 31, 2024	JANUS HENDERSON GROUP PLC	1.54%	2.23M	60.49M	826.37K	+58.90%
Mar 31, 2024	AMERIPRISE FINANCIAL INC	1.89%	2.74M	74.21M	452.85K	+19.84%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	2.18%	3.16M	85.85M	94.37K	+3.07%
Mar 31, 2024	PALO ALTO INVESTORS LP	3.05%	4.42M	120.01M	-1.09M	-19.75%
Mar 31, 2024	DEEP TRACK CAPITAL, LP	3.3%	4.78M	129.78M	-566.32K	-10.59%
Mar 31, 2024	STATE STREET CORP	4.08%	5.91M	160.21M	-24.81K	-0.42%
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	7.44%	10.77M	292.17M	5.6K	+0.05%
Mar 31, 2024	RHUMBLINE ADVISERS	0.14%	207.66K	5.63M	3.97K	+1.95%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.16%	232.68K	6.31M	20.65K	+9.74%
Mar 31, 2024	BNP PARIBAS ARBITRAGE, SNC	0.17%	239.98K	6.51M	18.41K	+8.31%
Mar 31, 2024	ALLY BRIDGE GROUP (NY) LLC	0.17%	250K	6.78M	250K	+100.00%
Mar 31, 2024	SWISS NATIONAL BANK	0.19%	268.4K	7.28M	-800	-0.30%
Mar 31, 2024	STEMPOINT CAPITAL LP	0.19%	272.45K	7.39M	98.87K	+56.96%
Mar 31, 2024	SCOUT INVESTMENTS, INC.	0.19%	275.67K	7.37M	-17.53K	-5.98%
Mar 31, 2024	JPMORGAN CHASE & CO	0.2%	289.53K	7.85M	-92.96K	-24.30%
Mar 31, 2024	PEREGRINE CAPITAL MANAGEMENT LLC	0.2%	290.17K	7.87M	86	+0.03%
Mar 31, 2024	WCM INVESTMENT MANAGEMENT, LLC	0.22%	320K	8.68M	24.67K	+8.35%
Mar 31, 2024	BLEICHROEDER LP	0.22%	325K	8.82M	0	0
Mar 31, 2024	CITIGROUP INC	0.23%	326.57K	8.86M	183.29K	+127.92%
Mar 31, 2024	RAFFERTY ASSET MANAGEMENT, LLC	0.23%	329.64K	8.94M	8.55K	+2.66%
Mar 31, 2024	ENSIGN PEAK ADVISORS, INC	0.24%	341.57K	9.27M	271.56K	+387.89%
Mar 31, 2024	C WORLDWIDE GROUP HOLDING A/S	0.24%	343.11K	9.31M	0	0
Mar 31, 2024	UBS GROUP AG	0.26%	381.06K	10.34M	80.88K	+26.94%
Mar 31, 2024	CANDRIAM S.C.A.	0.27%	390.2K	10.59M	80K	+25.79%
Mar 31, 2024	TD ASSET MANAGEMENT INC	0.3%	427.18K	11.59B	-36.35K	-7.84%
Mar 31, 2024	LONG FOCUS CAPITAL MANAGEMENT, LLC	0.3%	431.65K	11.71M	60K	+16.14%
Mar 31, 2024	EMERALD MUTUAL FUND ADVISERS TRUST	0.33%	484.71K	13.15M	-263.63K	-35.23%
Mar 31, 2024	PANAGORA ASSET MANAGEMENT INC	0.36%	514.83K	13.97M	85.83K	+20.01%
Mar 31, 2024	EAGLE ASSET MANAGEMENT INC	0.36%	524.37K	14.01M	-24.26K	-4.42%
Mar 31, 2024	BALYASNY ASSET MANAGEMENT L.P.	0.31%	450.39K	12.22M	-493.04K	-52.26%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.37%	537.23K	14.58M	160.02K	+42.42%
Mar 31, 2024	OCTAGON CAPITAL ADVISORS LP	0.79%	1.14M	30.93M	-144K	-11.22%
Mar 31, 2024	SIO CAPITAL MANAGEMENT, LLC	0.94%	1.36M	36.97M	501K	+58.14%
Dec 31, 2023	FMR LLC	3.56%	5.09M	157.79M	786.66K	+18.27%
Dec 31, 2023	PALO ALTO INVESTORS LP	3.86%	5.51M	170.81M	-377.77K	-6.41%
Dec 31, 2023	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	4.09%	5.85M	181.31M	-2.47M	-29.72%
Dec 31, 2023	STATE STREET CORP	4.15%	5.93M	183.77M	875.55K	+17.32%
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	7.53%	10.76M	333.57M	356.56K	+3.43%
Dec 31, 2023	BLACKROCK INC.	8.04%	11.49M	356.15M	1.1M	+10.60%
Dec 31, 2023	VANGUARD GROUP INC	9.89%	14.13M	437.75M	-219.99K	-1.53%
Dec 31, 2023	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.42%	600K	18.59M	0	0
Dec 31, 2023	TWO SIGMA ADVISERS, LP	0.44%	629.2K	19.5M	-196.2K	-23.77%
Dec 31, 2023	EVENTIDE ASSET MANAGEMENT, LLC	0.44%	635.19K	19.68M	0	0
Dec 31, 2023	FIRST LIGHT ASSET MANAGEMENT, LLC	0.45%	646.06K	20.02M	2.47K	+0.38%
Dec 31, 2023	D. E. SHAW & CO., INC.	0.45%	646.91K	20.05M	450.18K	+228.83%
Dec 31, 2023	AMERICAN CENTURY COMPANIES INC	0.46%	662.2K	20.52M	47.67K	+7.76%
Dec 31, 2023	FIL LTD	0.48%	691.43K	21.43M	-139.77K	-16.82%
Dec 31, 2023	EMERALD MUTUAL FUND ADVISERS TRUST	0.52%	748.34K	23.19M	3.61K	+0.48%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.53%	761.77K	23.61M	-101.75K	-11.78%
Dec 31, 2023	SIO CAPITAL MANAGEMENT, LLC	0.6%	861.7K	26.7M	861.7K	+100.00%
Dec 31, 2023	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	0.63%	895.95K	27.77M	39.75K	+4.64%
Dec 31, 2023	HOOD RIVER CAPITAL MANAGEMENT LLC	0.63%	905.82K	28.07M	905.82K	+100.00%
Dec 31, 2023	EMERALD ADVISERS, LLC	0.65%	930.85K	28.85M	-6.67K	-0.71%
Dec 31, 2023	BALYASNY ASSET MANAGEMENT L.P.	0.66%	943.43K	29.24M	862.06K	+1,059.35%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.73%	1.04M	32.35M	-165.2K	-13.66%
Dec 31, 2023	CITADEL ADVISORS LLC	0.73%	1.05M	32.42M	466.83K	+80.57%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.79%	1.13M	34.97M	28.63K	+2.60%
Dec 31, 2023	OCTAGON CAPITAL ADVISORS LP	0.9%	1.28M	39.79M	0	0
Dec 31, 2023	SAMLYN CAPITAL, LLC	0.9%	1.29M	39.88M	-94.19K	-6.82%
Dec 31, 2023	GW&K INVESTMENT MANAGEMENT, LLC	0.9%	1.29M	40.03M	-60.5K	-4.47%
Dec 31, 2023	NOVO HOLDINGS A/S	0.94%	1.34M	41.51M	0	0
Dec 31, 2023	PRINCIPAL FINANCIAL GROUP INC	0.95%	1.36M	42.13M	69.28K	+5.37%
Dec 31, 2023	NORTHERN TRUST CORP	0.96%	1.37M	42.53M	25.81K	+1.92%
Dec 31, 2023	JANUS HENDERSON GROUP PLC	0.98%	1.4M	43.48M	-511.71K	-26.72%
Dec 31, 2023	MARSHALL WACE, LLP	1.01%	1.44M	44.62M	874.01K	+154.48%
Dec 31, 2023	NORGES BANK	1.02%	1.45M	45.03M	1.45M	+100.00%
Dec 31, 2023	MORGAN STANLEY	1.07%	1.53M	47.56M	856.02K	+126.12%
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	1.12%	1.61M	49.74M	-569.83K	-26.20%
Dec 31, 2023	HOLOCENE ADVISORS, LP	1.13%	1.61M	50.04M	-193.63K	-10.71%
Dec 31, 2023	RTW INVESTMENTS, LP	1.31%	1.87M	57.8M	0	0
Dec 31, 2023		0.63%	900K	27.89M	900K	+100.00%
Dec 31, 2023	ALLIANCEBERNSTEIN L.P.	1.5%	2.15M	66.56M	-146.89K	-6.40%
Dec 31, 2023	AMERIPRISE FINANCIAL INC	1.6%	2.28M	70.73M	405.78K	+21.62%
Dec 31, 2023	BELLEVUE GROUP AG	1.6%	2.29M	71M	-871.78K	-27.56%
Dec 31, 2023	LOOMIS SAYLES & CO L P	1.63%	2.33M	72.25M	-51.53K	-2.16%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	1.65%	2.36M	73.04M	-174.86K	-6.91%
Dec 31, 2023	SUVRETTA CAPITAL MANAGEMENT, LLC	1.88%	2.68M	83.19M	-761.85K	-22.11%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	2.15%	3.07M	95.13M	195.68K	+6.81%
Dec 31, 2023	FRANKLIN RESOURCES INC	2.38%	3.4M	105.26M	-15.11K	-0.44%
Dec 31, 2023	WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC	2.98%	4.26M	131.91M	14.75K	+0.35%
Dec 31, 2023	MACQUARIE GROUP LTD	3.26%	4.65M	144.15M	-2.28K	-0.05%
Dec 31, 2023	DEEP TRACK CAPITAL, LP	3.74%	5.35M	165.8M	-650K	-10.83%

Insiders

Among the INSM insiders holding of 0.65% of the stake in company, LEWIS WILLIAM, Chair and CEO, holds the largest shares of 301.19K. SHAROKY MELVIN MD, director, is the second largest INSM insider with ownership of 243.95K shares. WISE JOHN DRAYTON, Chief Commercial Officer, stands third with possession of 133.02K shares of that stake.

Insiders	Designation	Shares Held
LEWIS WILLIAM	Chair and CEO	301.19K
SHAROKY MELVIN MD	director	243.95K
WISE JOHN DRAYTON	Chief Commercial Officer	133.02K
ADSETT ROGER	Chief Operating Officer	106.81K
MCGIRR DAVID W J	director	97.72K
FLAMMER MARTINA M.D.	Chief Medical Officer	83.24K
BONSTEIN SARA	Chief Financial Officer	79.76K
ANDERSON ELIZABETH M	director	58.73K
LEE LEO	director	54.68K
SMITH MICHAEL ALEXANDER	Chief Legal Officer	51.87K
SCHAEFFER ORLOV S NICOLE	Chief People Strategy Officer	41.75K
DESJARDINS CLARISSA	director	3.03K

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Mar 05, 2026	LEWIS WILLIAM	SALE	147.54	2.13K	313.97K	301.19K
Feb 24, 2026	SMITH MICHAEL ALEXANDER	SALE	156.53	15.77K	2.47M	51.87K
Feb 19, 2026	LEWIS WILLIAM	SALE	153.38	1.03K	157.98K	301.19K
Feb 09, 2026	LEWIS WILLIAM	SALE	148.83	1.29K	191.54K	301.19K
Feb 05, 2026	FLAMMER MARTINA M.D.	SALE	152.44	869	132.47K	83.24K
Feb 03, 2026	LEWIS WILLIAM	SALE	156.34	3.01K	470.43K	303.88K
Feb 03, 2026	BONSTEIN SARA	SALE	156.34	748	116.94K	79.76K
Feb 03, 2026	FLAMMER MARTINA M.D.	SALE	155.77	795	123.84K	84.11K
Feb 03, 2026	ADSETT ROGER	SALE	156.17	791	123.53K	106.81K
Feb 03, 2026	SMITH MICHAEL ALEXANDER	SALE	156.27	640	100.01K	56.4K
Feb 02, 2026	FLAMMER MARTINA M.D.	SALE	156.86	100	15.69K	84.91K
Jan 20, 2026	LEWIS WILLIAM	SALE	160.70	254	40.82K	306.89K
Jan 12, 2026	LEWIS WILLIAM	SALE	174.86	315	55.08K	306.89K
Jan 09, 2026	FLAMMER MARTINA M.D.	SALE	186.19	1.89K	351.34K	84.91K
Jan 08, 2026	LEWIS WILLIAM	SALE	174.17	3.22K	561.35K	315.41K
Jan 08, 2026	FLAMMER MARTINA M.D.	SALE	174.17	3.25K	566.23K	86.79K
Jan 08, 2026	ADSETT ROGER	SALE	174.17	2.06K	358.62K	107.6K
Jan 08, 2026	SMITH MICHAEL ALEXANDER	SALE	174.17	1.05K	183.4K	57.04K
Jan 08, 2026	BONSTEIN SARA	SALE	174.17	1.45K	252.02K	80.51K
Jan 07, 2026	LEWIS WILLIAM	SALE	175.07	2.36K	412.64K	318.63K
Jan 07, 2026	ADSETT ROGER	SALE	175.07	802	140.41K	109.66K
Jan 07, 2026	SMITH MICHAEL ALEXANDER	SALE	175.07	709	124.12K	58.09K
Jan 07, 2026	BONSTEIN SARA	SALE	175.07	1.68K	293.77K	81.95K
Jan 07, 2026	FLAMMER MARTINA M.D.	SALE	175.84	1.43K	252.15K	91.71K
Jan 06, 2026	FLAMMER MARTINA M.D.	SALE	173.33	1.62K	279.93K	93.14K
Jan 06, 2026	LEWIS WILLIAM	SALE	173.33	4.1K	709.96K	320.99K
Jan 06, 2026	BONSTEIN SARA	SALE	173.33	1.52K	262.94K	83.63K
Jan 06, 2026	ADSETT ROGER	SALE	173.33	1.43K	247.69K	110.46K
Jan 06, 2026	SMITH MICHAEL ALEXANDER	SALE	173.33	1.4K	241.97K	58.8K
Jan 05, 2026	FLAMMER MARTINA M.D.	SALE	175.73	702	123.36K	94.75K
Jan 02, 2026	SCHAEFFER ORLOV S NICOLE	SALE	177.78	200	35.56K	41.75K
Dec 18, 2025	LEWIS WILLIAM	SALE	171.20	51	8.73K	303.91K
Dec 05, 2025	SHAROKY MELVIN MD	SALE	205.01	20K	4.1M	243.95K
Dec 04, 2025	LEWIS WILLIAM	SALE	207.42	1.04K	215.72K	303.91K
Dec 01, 2025	FLAMMER MARTINA M.D.	SALE	207.03	5.89K	1.22M	84.67K
Nov 24, 2025	ANDERSON ELIZABETH M	SALE	204.58	5K	1.02M	58.73K
Nov 17, 2025	LEE LEO	SALE	197.40	15.17K	3M	54.68K
Nov 14, 2025	ANDERSON ELIZABETH M	SALE	195.87	10K	1.96M	63.73K
Nov 12, 2025	SCHAEFFER ORLOV S NICOLE	SALE	195.88	164	32.12K	36.46K
Nov 11, 2025	FLAMMER MARTINA M.D.	SALE	191.04	2.91K	556.5K	83.11K
Nov 03, 2025	SMITH MICHAEL ALEXANDER	SALE	187.97	1.4K	263.16K	54.9K
Sep 12, 2025	SHAROKY MELVIN MD	SALE	145.39	10K	1.45M	262.68K
Sep 12, 2025	SCHAEFFER ORLOV S NICOLE	SALE	147.46	6.16K	908.06K	36.46K
Sep 02, 2025	SMITH MICHAEL ALEXANDER	SALE	145.89	1.18K	172.59K	54.9K
Sep 02, 2025	FLAMMER MARTINA M.D.	SALE	146.05	34.62K	5.06M	83.11K
Aug 20, 2025	SHAROKY MELVIN MD	SALE	129.50	10K	1.3M	274.52K
Aug 19, 2025	ADSETT ROGER	SALE	128.27	4.81K	616.59K	105.64K
Aug 18, 2025	LEWIS WILLIAM	SALE	129.47	1.42K	183.33K	233.92K
Aug 14, 2025	SCHAEFFER ORLOV S NICOLE	SALE	128.16	700	89.71K	79.76K
Aug 12, 2025	SHAROKY MELVIN MD	SALE	121.58	10K	1.22M	290.62K
Aug 04, 2025	FLAMMER MARTINA M.D.	SALE	109.50	8.72K	954.29K	83.11K
Aug 04, 2025	LEWIS WILLIAM	SALE	110.91	1.94K	214.94K	233.92K
Jul 21, 2025	BONSTEIN SARA	SALE	103.03	26.31K	2.71M	73.51K
Jul 15, 2025	SMITH MICHAEL ALEXANDER	SALE	102.51	933	95.64K	66.39K
Jul 15, 2025	LEWIS WILLIAM	SALE	103.32	170	17.56K	233.92K
Jul 11, 2025	SMITH MICHAEL ALEXANDER	SALE	96.41	748	72.11K	67.33K
Jul 07, 2025	BONSTEIN SARA	SALE	96.19	22.18K	2.13M	84.02K
Jul 01, 2025	LEWIS WILLIAM	SALE	99.61	815	81.18K	233.92K
Jun 23, 2025	BONSTEIN SARA	SALE	102.15	8.66K	884.72K	93.54K
Jun 16, 2025	ADSETT ROGER	SALE	99.32	4.19K	415.75K	130.64K
Jun 16, 2025	LEWIS WILLIAM	SALE	101.23	41.78K	4.23M	233.92K
Jun 11, 2025	SCHAEFFER ORLOV S NICOLE	SALE	96.02	500	48.01K	89.41K
Jun 11, 2025	FLAMMER MARTINA M.D.	SALE	94.50	19.42K	1.84M	83.11K
Jun 10, 2025	BONSTEIN SARA	SALE	91.66	100	9.17K	103.41K
Jun 10, 2025	SCHAEFFER ORLOV S NICOLE	SALE	88.64	38.3K	3.39M	118.58K
Jun 10, 2025	FLAMMER MARTINA M.D.	SALE	88.64	25.74K	2.28M	83.11K
Jun 05, 2025	SMITH MICHAEL ALEXANDER	SALE	73.50	1.88K	138.11K	67.72K
Jun 04, 2025	MCGIRR DAVID W J	SALE	73.27	3K	219.81K	97.72K
Jun 03, 2025	SCHAEFFER ORLOV S NICOLE	SALE	71.50	1.64K	117.4K	118.58K
Jun 03, 2025	MCGIRR DAVID W J	SALE	71.30	3.25K	231.73K	100.72K
Jun 03, 2025	LEWIS WILLIAM	SALE	71.50	5.47K	391.25K	308.76K
Jun 03, 2025	FLAMMER MARTINA M.D.	SALE	71.50	1.69K	120.55K	83.11K
Jun 03, 2025	BONSTEIN SARA	SALE	71.50	1.58K	112.9K	113.29K
Jun 03, 2025	ADSETT ROGER	SALE	71.50	1.86K	132.99K	141.32K
Jun 03, 2025	SMITH MICHAEL ALEXANDER	SALE	71.50	1.45K	103.53K	69.6K
Jun 02, 2025	LEWIS WILLIAM	SALE	71.94	1.43K	102.87K	233.92K
May 30, 2025	SMITH MICHAEL ALEXANDER	SALE	70.00	20K	1.4M	71.05K
May 21, 2025	DESJARDINS CLARISSA	PURCHASE	66.35	1.13K	74.98K	3.03K
May 20, 2025	DESJARDINS CLARISSA	PURCHASE	66.87	1.9K	126.72K	1.9K
May 20, 2025	LEWIS WILLIAM	SALE	68.54	1.72K	117.61K	233.92K
May 16, 2025	FLAMMER MARTINA M.D.	SALE	67.53	1.8K	121.49K	84.8K
May 15, 2025	FLAMMER MARTINA M.D.	SALE	65.47	9.93K	649.79K	86.6K
May 14, 2025	BONSTEIN SARA	SALE	65.61	1.63K	107.21K	108.36K
May 14, 2025	ADSETT ROGER	SALE	65.61	1.93K	126.3K	136.68K
May 14, 2025	LEWIS WILLIAM	SALE	65.61	3.77K	247.42K	312.97K
May 14, 2025	SMITH MICHAEL ALEXANDER	SALE	65.61	409	26.83K	91.79K
May 14, 2025	FLAMMER MARTINA M.D.	SALE	65.61	1.74K	114.42K	90.01K
May 14, 2025	SCHAEFFER ORLOV S NICOLE	SALE	65.61	1.24K	81.09K	114.64K
May 13, 2025	ADSETT ROGER	SALE	67.81	7.48K	507.35K	138.6K
May 13, 2025	SCHAEFFER ORLOV S NICOLE	SALE	67.81	5K	338.98K	115.88K
May 13, 2025	SMITH MICHAEL ALEXANDER	SALE	67.81	4.41K	298.84K	92.2K
May 13, 2025	BONSTEIN SARA	SALE	67.81	8.87K	601.47K	109.99K
May 13, 2025	FLAMMER MARTINA M.D.	SALE	67.81	8.41K	570.15K	91.76K
May 13, 2025	LEWIS WILLIAM	SALE	67.70	7.7K	521.22K	316.74K
May 01, 2025	LEWIS WILLIAM	SALE	72.78	4.2K	305.75K	233.92K
Apr 15, 2025	LEWIS WILLIAM	SALE	71.30	600	42.78K	233.92K
Apr 01, 2025	LEWIS WILLIAM	SALE	75.26	805	60.58K	233.92K
Mar 17, 2025	LEWIS WILLIAM	SALE	77.83	2.74K	213.02K	233.92K
Mar 03, 2025	LEWIS WILLIAM	SALE	80.90	46	3.72K	233.92K
Feb 18, 2025	BONSTEIN SARA	SALE	81.00	700	56.7K	118.86K
Feb 18, 2025	LEWIS WILLIAM	SALE	81.81	300	24.54K	233.92K
Feb 12, 2025	BONSTEIN SARA	SALE	80.00	5.02K	401.52K	137.19K
Feb 11, 2025	BONSTEIN SARA	SALE	80.00	13.3K	1.06M	142.2K
Feb 10, 2025	ADSETT ROGER	SALE	79.33	26.14K	2.07M	146.08K
Feb 10, 2025	FLAMMER MARTINA M.D.	SALE	79.33	23.01K	1.83M	100.17K
Feb 07, 2025	FLAMMER MARTINA M.D.	SALE	79.59	60	4.78K	137.99K
Feb 07, 2025	WISE JOHN DRAYTON	SALE	78.91	10	789.1	133.02K
Feb 07, 2025	ADSETT ROGER	SALE	79.57	100	7.96K	189.06K
Feb 06, 2025	SCHAEFFER ORLOV S NICOLE	SALE	80.90	23.5K	1.9M	120.88K
Feb 06, 2025	ADSETT ROGER	SALE	80.90	45.61K	3.69M	189.16K
Feb 06, 2025	WISE JOHN DRAYTON	SALE	80.90	7.91K	639.92K	133.03K
Feb 06, 2025	LEWIS WILLIAM	SALE	80.90	79.35K	6.42M	453.89K
Feb 06, 2025	BONSTEIN SARA	SALE	80.90	28.39K	2.3M	155.51K
Feb 06, 2025	FLAMMER MARTINA M.D.	SALE	80.90	33.06K	2.67M	138.05K
Feb 06, 2025	SMITH MICHAEL ALEXANDER	SALE	80.90	20.65K	1.67M	96.61K
Feb 03, 2025	LEWIS WILLIAM	SALE	78.40	2.58K	202.35K	233.92K
Jan 30, 2025	SCHAEFFER ORLOV S NICOLE	SALE	80.00	91.14K	7.29M	97.08K
Jan 15, 2025	LEWIS WILLIAM	SALE	71.01	631	44.81K	233.92K
Jan 14, 2025	FLAMMER MARTINA M.D.	SALE	68.72	1.38K	95.11K	100.17K
Jan 14, 2025	SCHAEFFER ORLOV S NICOLE	SALE	68.72	872	59.92K	97.08K
Jan 14, 2025	ADSETT ROGER	SALE	68.72	1.46K	100.13K	146.08K
Jan 10, 2025	FLAMMER MARTINA M.D.	SALE	63.62	4.8K	305.44K	101.55K
Jan 10, 2025	ADSETT ROGER	SALE	63.62	3.6K	229.29K	147.54K
Jan 10, 2025	SCHAEFFER ORLOV S NICOLE	SALE	63.62	3.09K	196.71K	97.96K
Jan 10, 2025	WISE JOHN DRAYTON	SALE	65.40	287	18.77K	125.56K
Jan 10, 2025	LEWIS WILLIAM	SALE	63.36	2.98K	188.69K	392.59K
Jan 10, 2025	SMITH MICHAEL ALEXANDER	SALE	63.38	319	20.22K	69.97K
Jan 10, 2025	BONSTEIN SARA	SALE	63.72	1.07K	67.93K	118.86K
Jan 08, 2025	WISE JOHN DRAYTON	SALE	66.21	392	25.95K	119.19K
Jan 08, 2025	FLAMMER MARTINA M.D.	SALE	66.16	1.7K	112.6K	101.06K
Jan 08, 2025	SCHAEFFER ORLOV S NICOLE	SALE	65.84	1.21K	79.6K	96.31K
Jan 08, 2025	ADSETT ROGER	SALE	66.10	1.88K	124.4K	145.78K
Jan 08, 2025	LEWIS WILLIAM	SALE	65.96	4K	263.77K	372.74K
Jan 08, 2025	BONSTEIN SARA	SALE	66.05	1.46K	96.7K	113.27K
Jan 08, 2025	SMITH MICHAEL ALEXANDER	SALE	66.21	1.06K	70.45K	64.58K
Jan 07, 2025	ADSETT ROGER	SALE	65.95	2.44K	161.18K	147.67K
Jan 07, 2025	LEWIS WILLIAM	SALE	66.02	8.22K	542.55K	376.74K
Jan 07, 2025	SMITH MICHAEL ALEXANDER	SALE	65.98	2.31K	152.15K	65.64K
Jan 07, 2025	WISE JOHN DRAYTON	SALE	65.87	2.91K	191.55K	119.58K
Jan 07, 2025	FLAMMER MARTINA M.D.	SALE	65.91	3.34K	220.4K	102.77K
Jan 07, 2025	SCHAEFFER ORLOV S NICOLE	SALE	65.88	2.6K	171.02K	97.52K
Jan 07, 2025	BONSTEIN SARA	SALE	65.70	3.47K	227.98K	114.74K
Jan 02, 2025	LEWIS WILLIAM	SALE	69.86	6.83K	477.14K	233.92K
Dec 19, 2024	LEWIS WILLIAM	SALE	70.61	1.59K	112.27K	233.92K
Dec 12, 2024	LEWIS WILLIAM	SALE	74.22	181	13.43K	233.92K
Sep 16, 2024	FLAMMER MARTINA M.D.	SALE	74.92	13.44K	1.01M	106.13K
Sep 13, 2024	SMITH MICHAEL ALEXANDER	SALE	74.75	9K	672.75K	67.86K
Sep 13, 2024	FLAMMER MARTINA M.D.	SALE	74.90	26.97K	2.02M	106.13K
Sep 10, 2024	SCHAEFFER ORLOV S NICOLE	SALE	71.88	9.58K	688.75K	100.1K
Sep 06, 2024	FLAMMER MARTINA M.D.	SALE	72.61	9.06K	658.14K	106.13K
Aug 12, 2024	SMITH MICHAEL ALEXANDER	SALE	73.65	20.42K	1.5M	88.73K
Aug 12, 2024	SCHAEFFER ORLOV S NICOLE	SALE	72.49	9.47K	686.41K	100.1K
Jun 10, 2024	FLAMMER MARTINA M.D.	SALE	60.00	21.2K	1.27M	106.13K
Jun 03, 2024	SCHAEFFER ORLOV S NICOLE	SALE	55.33	55K	3.04M	108.76K
May 30, 2024	FLAMMER MARTINA M.D.	SALE	55.00	21.2K	1.17M	106.13K
May 29, 2024	BONSTEIN SARA	SALE	50.00	220.56K	11.03M	117.48K
May 28, 2024	SMITH MICHAEL ALEXANDER	SALE	49.53	44.72K	2.22M	88.83K
May 28, 2024	SCHAEFFER ORLOV S NICOLE	SALE	49.53	27.5K	1.36M	108.76K
May 28, 2024	FLAMMER MARTINA M.D.	SALE	49.62	103.81K	5.15M	106.13K
May 28, 2024	WISE JOHN DRAYTON	SALE	50.00	6.25K	312.5K	121.66K
May 28, 2024	BONSTEIN SARA	SALE	50.01	20.72K	1.04M	338.05K
May 17, 2024	ADSETT ROGER	SALE	25.09	5.95K	149.16K	149.28K
May 17, 2024	FLAMMER MARTINA M.D.	SALE	25.09	4.64K	116.47K	106.13K
May 14, 2024	SCHAEFFER ORLOV S NICOLE	SALE	25.53	6.51K	166.15K	108.76K
May 14, 2024	SMITH MICHAEL ALEXANDER	SALE	25.40	5.09K	129.36K	94.58K
May 14, 2024	FLAMMER MARTINA M.D.	SALE	25.47	10.64K	271K	110.78K
May 14, 2024	WISE JOHN DRAYTON	SALE	25.47	5.09K	129.59K	123.26K
May 14, 2024	LEWIS WILLIAM	SALE	25.52	22.2K	566.49K	384.13K
May 14, 2024	BONSTEIN SARA	SALE	25.32	11.09K	280.75K	117.48K
May 14, 2024	ADSETT ROGER	SALE	25.50	7.86K	200.35K	155.22K
Jan 12, 2024	ADSETT ROGER	SALE	28.63	5.25K	150.34K	148.56K
Jan 12, 2024	FLAMMER MARTINA M.D.	SALE	28.63	4.67K	133.62K	106.9K
Jan 10, 2024	ADSETT ROGER	SALE	28.90	3.54K	102.19K	153.81K
Jan 10, 2024	FLAMMER MARTINA M.D.	SALE	28.90	1.25K	35.98K	111.57K
Jan 09, 2024	LEWIS WILLIAM	SALE	28.72	9.89K	283.95K	363.65K
Jan 09, 2024	FLAMMER MARTINA M.D.	SALE	29.01	4.72K	136.78K	112.81K
Jan 09, 2024	ADSETT ROGER	SALE	29.25	3.84K	112.23K	157.35K
Jan 09, 2024	BONSTEIN SARA	SALE	29.18	4.5K	131.22K	114.05K
Jan 09, 2024	SCHAEFFER ORLOV S NICOLE	SALE	28.74	3.17K	90.96K	101.98K
Jan 09, 2024	WISE JOHN DRAYTON	SALE	28.78	1.86K	53.56K	113.83K
Jan 09, 2024	SMITH MICHAEL ALEXANDER	SALE	28.76	2.37K	68.25K	86.36K
Jan 08, 2024	LEWIS WILLIAM	SALE	29.88	20.17K	602.65K	373.54K
Jan 05, 2024	LEWIS WILLIAM	SALE	29.26	6.98K	204.2K	373.54K
Jan 05, 2024	WISE JOHN DRAYTON	SALE	29.32	1.17K	34.22K	115.69K
Jan 05, 2024	SCHAEFFER ORLOV S NICOLE	SALE	29.28	1.46K	42.66K	105.15K
Jan 05, 2024	ADSETT ROGER	SALE	29.21	3.04K	88.86K	161.18K
Jan 05, 2024	FLAMMER MARTINA M.D.	SALE	29.20	1.39K	40.48K	117.53K
Jan 05, 2024	SMITH MICHAEL ALEXANDER	SALE	29.30	627	18.37K	88.74K
Jan 03, 2024	WISE JOHN DRAYTON	SALE	29.19	20.07K	585.87K	103.98K
Dec 28, 2023	SCHAEFFER ORLOV S NICOLE	SALE	32.00	22.29K	713.22K	94.55K
Dec 22, 2023	FLAMMER MARTINA M.D.	SALE	30.00	28.31K	849.3K	106.04K
Dec 22, 2023	BONSTEIN SARA	SALE	30.00	13.2K	395.97K	105.24K
Oct 27, 2023	LEWIS WILLIAM	SALE	25.08	1.32K	33.16K	0
Jul 11, 2023	SMITH MICHAEL ALEXANDER	SALE	20.18	740	14.93K	77.14K
Jun 13, 2023	FLAMMER MARTINA M.D.	SALE	19.27	8.87K	170.89K	106.04K
Jun 13, 2023	ADSETT ROGER	SALE	19.32	8.98K	173.51K	151.35K
May 25, 2023	WISE JOHN DRAYTON	SALE	18.95	3.37K	63.79K	102.68K
May 17, 2023	SMITH MICHAEL ALEXANDER	SALE	18.18	1.26K	22.96K	77.08K
May 17, 2023	LEWIS WILLIAM	SALE	18.12	7.1K	128.63K	341.35K
May 17, 2023	SCHAEFFER ORLOV S NICOLE	SALE	18.16	1.97K	35.81K	93.53K
May 17, 2023	WISE JOHN DRAYTON	SALE	18.17	1.91K	34.76K	106.05K
May 17, 2023	ADSETT ROGER	SALE	18.12	2.45K	44.36K	160.33K
May 16, 2023	SCHAEFFER ORLOV S NICOLE	SALE	18.45	1.22K	22.45K	95.5K
May 16, 2023	ADSETT ROGER	SALE	18.39	1.52K	27.97K	162.78K
May 16, 2023	BONSTEIN SARA	SALE	18.47	1.61K	29.74K	117.62K
May 16, 2023	SMITH MICHAEL ALEXANDER	SALE	18.43	475	8.75K	78.35K
May 16, 2023	LEWIS WILLIAM	SALE	18.41	3.71K	68.37K	348.44K
May 16, 2023	FLAMMER MARTINA M.D.	SALE	18.43	1.72K	31.66K	114.91K
May 16, 2023	WISE JOHN DRAYTON	SALE	18.44	381	7.03K	107.96K
May 15, 2023	FLAMMER MARTINA M.D.	SALE	19.28	2.58K	49.67K	116.62K
May 15, 2023	SCHAEFFER ORLOV S NICOLE	SALE	19.22	1.83K	35.17K	96.71K
May 15, 2023	SHAROKY MELVIN MD	PURCHASE	19.29	10K	192.9K	10K
May 15, 2023	ADSETT ROGER	SALE	19.27	2.85K	54.86K	164.3K
May 15, 2023	SMITH MICHAEL ALEXANDER	SALE	19.24	1.9K	36.5K	78.82K
May 15, 2023	WISE JOHN DRAYTON	SALE	19.29	593	11.44K	108.34K
May 15, 2023	LEWIS WILLIAM	SALE	19.23	6.05K	116.3K	352.16K
May 15, 2023	BONSTEIN SARA	SALE	19.30	2.21K	42.65K	119.23K
Jan 10, 2023	BONSTEIN SARA	SALE	18.12	2.86K	51.77K	66.03K
Jan 10, 2023	WISE JOHN DRAYTON	SALE	17.96	779	13.99K	77.27K
Jan 10, 2023	ADSETT ROGER	SALE	17.99	3.19K	57.46K	135.49K
Jan 10, 2023	SMITH MICHAEL ALEXANDER	SALE	17.93	1.84K	32.92K	54.33K
Jan 10, 2023	SCHAEFFER ORLOV S NICOLE	SALE	17.95	2.44K	43.71K	72.16K
Jan 10, 2023	LEWIS WILLIAM	SALE	18.00	6.99K	125.89K	265.07K
Jan 10, 2023	FLAMMER MARTINA M.D.	SALE	18.06	3.44K	62.11K	72.76K
Jan 05, 2023	ADSETT ROGER	SALE	19.75	3.04K	60.12K	131.08K
Jan 05, 2023	SMITH MICHAEL ALEXANDER	SALE	19.72	720	14.2K	49.84K
Jan 05, 2023	LEWIS WILLIAM	SALE	19.80	7.01K	138.76K	249.71K
Jan 05, 2023	SCHAEFFER ORLOV S NICOLE	SALE	19.73	1.45K	28.57K	68.26K
Jan 05, 2023	WISE JOHN DRAYTON	SALE	19.74	1.16K	22.9K	70.45K
Jan 05, 2023	FLAMMER MARTINA M.D.	SALE	19.73	1.37K	27.11K	65.06K
Nov 22, 2022	WISE JOHN DRAYTON	SALE	18.84	7.15K	134.78K	71.61K
Nov 22, 2022	ADSETT ROGER	SALE	18.80	11.86K	222.87K	134.13K
Nov 01, 2022	SHAROKY MELVIN MD	PURCHASE	17.70	10K	177K	15.9K
Oct 31, 2022	SHAROKY MELVIN MD	PURCHASE	17.53	20K	350.6K	281.02K
Oct 31, 2022	LEE LEO	PURCHASE	17.69	45K	796.05K	98.27K
Aug 10, 2022	WISE JOHN DRAYTON	SALE	27.79	258	7.17K	78.77K
Aug 08, 2022	LEWIS WILLIAM	SALE	27.75	161.19K	4.47M	0
Jul 12, 2022	SMITH MICHAEL ALEXANDER	SALE	23.40	941	22.02K	50.46K
Jul 07, 2022	LEWIS WILLIAM	SALE	23.00	96.61K	2.22M	256.72K
May 17, 2022	LEWIS WILLIAM	SALE	20.18	6K	121K	255.83K
May 16, 2022	ADSETT ROGER	SALE	18.45	1.39K	25.72K	148K
May 16, 2022	LEWIS WILLIAM	SALE	18.35	3.4K	62.35K	261.82K
May 16, 2022	SMITH MICHAEL ALEXANDER	SALE	20.37	1.06K	21.49K	50.58K
May 16, 2022	SCHAEFFER ORLOV S NICOLE	SALE	18.41	1.11K	20.51K	70.49K
May 16, 2022	FLAMMER MARTINA M.D.	SALE	18.51	1.57K	29.13K	66.43K
May 16, 2022	BONSTEIN SARA	SALE	18.51	1.43K	26.52K	54.68K
May 11, 2022	SHAROKY MELVIN MD	PURCHASE	17.20	20K	344K	262.62K
Mar 23, 2022	LEWIS WILLIAM	SALE	23.16	65.41K	1.51M	217.62K
Jan 12, 2022	ADSETT ROGER	SALE	24.58	1.22K	29.91K	121.94K
Jan 11, 2022	SCHAEFFER ORLOV S NICOLE	SALE	25.11	925	23.23K	56.96K
Jan 11, 2022	BONSTEIN SARA	SALE	25.11	1.15K	28.98K	35.98K
Jan 11, 2022	FLAMMER MARTINA M.D.	SALE	25.11	1.5K	37.54K	46.04K
Jan 11, 2022	LEWIS WILLIAM	SALE	25.11	2.87K	72.14K	217.62K
Jan 11, 2022	SMITH MICHAEL ALEXANDER	SALE	25.11	407	10.22K	37.43K
Jan 06, 2022	ADSETT ROGER	SALE	26.00	1.76K	45.73K	105.42K
Jan 06, 2022	LEWIS WILLIAM	SALE	26.00	5.34K	138.76K	189.76K
Jan 05, 2022	LEWIS WILLIAM	SALE	27.61	7.13K	196.75K	195.09K
Jan 05, 2022	ADSETT ROGER	SALE	27.61	3.07K	84.71K	107.18K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES120.22K41

NET SHARES-120.22K41

SHARES HELD5.85M41

% NET SHARES-102.05%0%

Frequently Asked Questions

Stock Outstanding Shares

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares4.52

Short Percent Of Float5

Shares Outstanding211.38M

Shares Float190.42M

Shares Short9.54M

Short Ratio3.67

Short % of Float

4.52%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

0.65% Percentage of Shares held by All Insiders

101.27% Percentage of Shares held by All Institutions

101.93% Percentage of Float held by Institutions

678

Number of Institutions Holding Shares

Institutional Ownership

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Dec 31, 2025	UBS GROUP AG	0.88%	1.87M	325.04M	221.4K	+13.45%
Dec 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.43%	915.42K	159.32M	482.08K	+111.25%
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.03%	4.3M	751.94M	539.63K	+14.35%
Dec 31, 2025	RTW INVESTMENTS, LP	2.29%	4.84M	842.85M	1.76M	+57.00%
Dec 31, 2025	D. E. SHAW & CO., INC.	2.05%	4.35M	757.25M	-1.31M	-23.09%
Dec 31, 2025	ORBIS ALLAN GRAY LTD	1.97%	4.18M	727.48M	929.09K	+28.58%
Dec 31, 2025	NORGES BANK	1.37%	2.91M	506.63M	2.91M	+100.00%
Dec 31, 2025	DUQUESNE FAMILY OFFICE LLC	0.7%	1.48M	257.88M	-941.68K	-38.86%
Dec 31, 2025	AQR CAPITAL MANAGEMENT LLC	0.22%	468.26K	81.5M	180.97K	+62.99%
Dec 31, 2025	CASTLE HOOK PARTNERS LP	0.59%	1.25M	218.17M	162.16K	+14.86%
Dec 31, 2025	SWISS NATIONAL BANK	0.27%	579.11K	100.79M	207.81K	+55.97%
Dec 31, 2025	WELLS FARGO & COMPANY/MN	0.28%	586.65K	102.1M	72.8K	+14.17%
Dec 31, 2025	DEUTSCHE BANK AG\	0.28%	590.03K	102.69M	385.68K	+188.73%
Dec 31, 2025	GW&K INVESTMENT MANAGEMENT, LLC	0.23%	482.67K	84.01M	-119.13K	-19.80%
Dec 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.4%	849.6K	147.86M	1.2K	+0.14%
Dec 31, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.45%	958.96K	167.26M	-181.86K	-15.94%
Dec 31, 2025	FIERA CAPITAL CORP	0.47%	992.89K	172.8M	183.77K	+22.71%
Dec 31, 2025	BANK OF NEW YORK MELLON CORP	0.66%	1.39M	241.92M	251.14K	+22.05%
Dec 31, 2025	EVENTIDE ASSET MANAGEMENT, LLC	0.23%	483.59K	84.16M	-521.52K	-51.89%
Dec 31, 2025	TIMESSQUARE CAPITAL MANAGEMENT, LLC	0.23%	490.51K	85.37M	65.42K	+15.39%
Dec 31, 2025	ROYAL BANK OF CANADA	0.24%	506.81K	88.21M	-848.52K	-62.61%
Dec 31, 2025	LEGAL & GENERAL GROUP PLC	0.26%	540.31K	94.04M	332.29K	+159.74%
Dec 31, 2025	JANE STREET GROUP, LLC	0.22%	463.6K	80.68B	-318.8K	-40.75%
Dec 31, 2025	JENNISON ASSOCIATES LLC	0.27%	562.3K	97.86M	-40.48K	-6.72%
Dec 31, 2025	MILLENNIUM MANAGEMENT LLC	0.62%	1.31M	228.28M	-1.02M	-43.85%
Dec 31, 2025	BANK OF AMERICA CORP /DE/	0.81%	1.73M	300.34M	123.88K	+7.73%
Dec 31, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.13%	276.28K	48.08M	-169.59K	-38.04%
Dec 31, 2025	NATIONAL PENSION SERVICE	0.13%	280.44K	48.81M	280.44K	+100.00%
Dec 31, 2025	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	0.16%	328.33K	57.16M	129.63K	+65.24%
Dec 31, 2025	PROSHARE ADVISORS LLC	0.16%	340.74K	59.3M	333.21K	+4,425.10%
Dec 31, 2025	FEDERATED HERMES, INC.	0.3%	632.3K	110.05M	304.08K	+92.64%
Dec 31, 2025	VICTORY CAPITAL MANAGEMENT INC	0.31%	646.71K	112.55M	291.81K	+82.22%
Dec 31, 2025	NUVEEN, LLC	0.31%	650.4K	113.2M	62.28K	+10.59%
Dec 31, 2025	LORD, ABBETT & CO. LLC	0.34%	720.9K	125.47M	-723.76K	-50.10%
Dec 31, 2025	MORGAN STANLEY	0.77%	1.63M	284.02M	668.28K	+69.35%
Dec 31, 2025	AMERIPRISE FINANCIAL INC	0.93%	1.97M	342.66M	-753.02K	-27.67%
Dec 31, 2025	INVESCO LTD.	1.29%	2.73M	474.58M	722.99K	+36.08%
Dec 31, 2025	FRANKLIN RESOURCES INC	1.3%	2.76M	479.57M	615.81K	+28.78%
Dec 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.91%	4.04M	703.03M	-2.89M	-41.72%
Dec 31, 2025	STATE STREET CORP	2.46%	5.2M	905.31M	1.22M	+30.55%
Dec 31, 2025	CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM	0.17%	354.91K	61.77M	44.02K	+14.16%
Dec 31, 2025	SEI INVESTMENTS CO	0.42%	890.17K	154.92M	296.29K	+49.89%
Dec 31, 2025	AFFINITY ASSET ADVISORS, LLC	0.21%	450K	78.32M	0	0
Dec 31, 2025	BARCLAYS PLC	0.21%	444.71K	77.4M	330.51K	+289.42%
Dec 31, 2025	SUMITOMO MITSUI TRUST HOLDINGS, INC.	0.21%	435.44K	75.78M	435.44K	+100.00%
Dec 31, 2025	CITADEL ADVISORS LLC	0.55%	1.16M	201.42M	-900.35K	-43.76%
Dec 31, 2025	VANGUARD GROUP INC	9.95%	21.08M	3.67B	1.14M	+5.72%
Dec 31, 2025	JEFFERIES FINANCIAL GROUP INC.	0.44%	926.34K	161.22M	818.24K	+756.95%
Dec 31, 2025	DARWIN GLOBAL MANAGEMENT, LTD.	9.89%	20.93M	3.64B	475.83K	+2.33%
Dec 31, 2025	FMR LLC	4.69%	9.93M	1.73B	746.97K	+8.14%
Dec 31, 2025	BAKER BROS. ADVISORS LP	3.11%	6.59M	1.15B	-110.74K	-1.65%
Dec 31, 2025	ARTISAN PARTNERS LIMITED PARTNERSHIP	2.29%	4.84M	843.01M	-93.93K	-1.90%
Dec 31, 2025	CAPITAL INTERNATIONAL INVESTORS	2.43%	5.15M	896.6M	-2.4M	-31.80%
Dec 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.49%	1.03M	178.8M	52.08K	+5.34%
Dec 31, 2025	GOLDMAN SACHS GROUP INC	0.59%	1.24M	216.63M	415.4K	+50.09%
Dec 31, 2025	JPMORGAN CHASE & CO	10.96%	23.2M	4.04B	151.84K	+0.66%
Dec 31, 2025	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.59%	1.25M	217.55M	-350K	-21.88%
Dec 31, 2025	NORTHERN TRUST CORP	0.58%	1.24M	215.54M	165.5K	+15.42%
Dec 31, 2025	WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC	0.58%	1.22M	212.52M	-333.96K	-21.48%
Dec 31, 2025	MACQUARIE MANAGEMENT HOLDINGS, INC.	0.56%	1.18M	205.89B	1.18M	+100.00%
Dec 31, 2025	NWI MANAGEMENT LP	0.47%	988.46K	172.03M	-32.54K	-3.19%
Dec 31, 2025	TWO SIGMA INVESTMENTS, LP	0.45%	962.16K	167.45M	189.38K	+24.51%
Dec 31, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.45%	943.31K	164.17M	430.56K	+83.97%
Dec 31, 2025	AMUNDI	0.43%	917K	159.59M	599.9K	+189.19%
Dec 31, 2025	SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC	0.43%	909.08K	158.22M	-132.77K	-12.74%
Dec 31, 2025	FIL LTD	0.4%	838.51K	145.93M	-13.45K	-1.58%
Dec 31, 2025	CLEARBRIDGE INVESTMENTS, LLC	0.39%	819.01K	142.54M	-249.01K	-23.31%
Dec 31, 2025	HOLOCENE ADVISORS, LP	0.38%	801.17K	139.43M	-282.52K	-26.07%
Dec 31, 2025	JANUS HENDERSON GROUP PLC	0.38%	800.56K	139.33M	-402.23K	-33.44%
Dec 31, 2025	RAYMOND JAMES FINANCIAL INC	0.37%	779.25K	135.65M	19.28K	+2.54%
Dec 31, 2025	PRINCIPAL FINANCIAL GROUP INC	0.36%	771.36K	134.25M	-92.94K	-10.75%
Dec 31, 2025	BLACKROCK, INC.	7.11%	15.07M	2.62B	2.7M	+21.84%
Dec 31, 2025	WESTFIELD CAPITAL MANAGEMENT CO LP	0.2%	432.52K	75.28M	-55.41K	-11.36%
Dec 31, 2025	CANDRIAM S.C.A.	0.19%	401.04K	69.8M	3.45K	+0.87%
Dec 31, 2025	DIMENSIONAL FUND ADVISORS LP	0.19%	399.07K	69.46M	12.4K	+3.21%
Dec 31, 2025	MARSHALL WACE, LLP	0.18%	389.88K	67.85M	-268.77K	-40.81%
Dec 31, 2025	ENSIGN PEAK ADVISORS, INC	0.18%	382.2K	66.52M	-259.83K	-40.47%
Dec 31, 2025	GATEWAY INVESTMENT ADVISERS LLC	0.17%	365K	63.52M	365K	+100.00%
Dec 31, 2025	SAMLYN CAPITAL, LLC	0.17%	369.58K	64.32M	76.93K	+26.29%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0.27%	513.85K	74M	254.64K	+98.24%
Sep 30, 2025	NUVEEN, LLC	0.31%	588.12K	84.7M	-865	-0.15%
Sep 30, 2025	ROYAL BANK OF CANADA	0.64%	1.36M	195.18M	927.53K	+216.81%
Sep 30, 2025	FIERA CAPITAL CORP	0.38%	809.12K	116.52M	61.08K	+8.17%
Sep 30, 2025	FMR LLC	4.34%	9.18M	1.32B	4.09M	+80.26%
Sep 30, 2025	D. E. SHAW & CO., INC.	2.67%	5.66M	814.73M	2.23M	+65.30%
Sep 30, 2025	ARTISAN PARTNERS LIMITED PARTNERSHIP	2.33%	4.94M	711.08M	1.62M	+48.98%
Sep 30, 2025	DUQUESNE FAMILY OFFICE LLC	1.14%	2.42M	349M	170K	+7.54%
Sep 30, 2025	LORD, ABBETT & CO. LLC	0.68%	1.44M	208.05M	-101.2K	-6.55%
Sep 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.59%	1.25M	180.37M	-1.61M	-56.20%
Sep 30, 2025	JANUS HENDERSON GROUP PLC	0.57%	1.2M	173.21M	-1.09M	-47.55%
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.54%	1.14M	164.01M	-58.57K	-4.89%
Sep 30, 2025	TWO SIGMA INVESTMENTS, LP	0.41%	772.78K	111.29M	396.27K	+105.25%
Sep 30, 2025	STATE STREET CORP	1.88%	3.98M	573.79M	-293.53K	-6.86%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.78%	3.76M	541.5M	418.72K	+12.53%
Sep 30, 2025	ORBIS ALLAN GRAY LTD	1.54%	3.25M	468.16M	1.73M	+113.29%
Sep 30, 2025	MILLENNIUM MANAGEMENT LLC	1.1%	2.34M	336.42M	214.4K	+10.10%
Sep 30, 2025	JPMORGAN CHASE & CO	12.18%	23.05M	3.32B	7.41M	+47.40%
Sep 30, 2025	VANGUARD GROUP INC	9.41%	19.94M	2.87B	2.29M	+12.99%
Sep 30, 2025	ENSIGN PEAK ADVISORS, INC	0.34%	642.03K	92.46M	77.65K	+13.76%
Sep 30, 2025	JENNISON ASSOCIATES LLC	0.32%	602.78K	86.81M	-112.83K	-15.77%
Sep 30, 2025	GW&K INVESTMENT MANAGEMENT, LLC	0.32%	601.8K	86.67M	-672.51K	-52.77%
Sep 30, 2025	SEI INVESTMENTS CO	0.31%	593.89K	85.53M	160.26K	+36.96%
Sep 30, 2025	ALLIANCEBERNSTEIN L.P.	0.41%	868.77K	125.11M	-474.44K	-35.32%
Sep 30, 2025	HOOD RIVER CAPITAL MANAGEMENT LLC	0.42%	881.4K	126.93M	-18.2K	-2.02%
Sep 30, 2025	MORGAN STANLEY	0.46%	963.63K	138.77M	-80.16K	-7.68%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.46%	975.28K	140.45M	-324.29K	-24.95%
Sep 30, 2025	PRINCIPAL FINANCIAL GROUP INC	0.41%	864.29K	124.47M	-483.73K	-35.88%
Sep 30, 2025	MACQUARIE GROUP LTD	0.34%	649.85K	93.58M	-481.08K	-42.54%
Sep 30, 2025	MAVERICK CAPITAL LTD	0.35%	656.54K	94.55M	-147.59K	-18.35%
Sep 30, 2025	MARSHALL WACE, LLP	0.35%	658.65K	94.85M	-454.71K	-40.84%
Sep 30, 2025	PERCEPTIVE ADVISORS LLC	0.37%	702.13K	101.11M	51.88K	+7.98%
Sep 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.38%	718.04K	103.41M	-441.66K	-38.08%
Sep 30, 2025	ARTIA GLOBAL PARTNERS LP	0.39%	732.21K	105.45M	-20.5K	-2.72%
Sep 30, 2025	RAYMOND JAMES FINANCIAL INC	0.4%	759.98K	109.44M	-24.57K	-3.13%
Sep 30, 2025	DARWIN GLOBAL MANAGEMENT, LTD.	9.66%	20.46M	2.9B	1.11M	+5.75%
Sep 30, 2025	FIL LTD	0.4%	851.95K	122.69M	-313.51K	-26.90%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.85%	1.6M	230.68M	375.07K	+30.57%
Sep 30, 2025	JANE STREET GROUP, LLC	0.37%	782.4K	112.67M	44.6K	+6.05%
Sep 30, 2025	CLEARBRIDGE INVESTMENTS, LLC	0.5%	1.07M	153.81M	-356.54K	-25.03%
Sep 30, 2025	NORTHERN TRUST CORP	0.51%	1.07M	154.51M	103.14K	+10.64%
Sep 30, 2025	HOLOCENE ADVISORS, LP	0.51%	1.08M	156.06M	-933.13K	-46.27%
Sep 30, 2025	CASTLE HOOK PARTNERS LP	0.52%	1.09M	157.17M	638.75K	+141.11%
Sep 30, 2025	WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC	0.73%	1.56M	223.94M	-110.55K	-6.64%
Sep 30, 2025	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.76%	1.6M	230.42M	0	0
Sep 30, 2025	UBS GROUP AG	0.78%	1.65M	237.07M	1.35M	+460.99%
Sep 30, 2025	INVESCO LTD.	0.95%	2M	288.58M	107.54K	+5.67%
Sep 30, 2025	CITADEL ADVISORS LLC	0.97%	2.06M	296.32M	524.36K	+34.20%
Sep 30, 2025	FRANKLIN RESOURCES INC	1.01%	2.14M	308.14M	-210.41K	-8.95%
Sep 30, 2025	BLACKROCK, INC.	5.84%	12.36M	1.78B	1.22M	+10.97%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	0.39%	829.32K	119.43M	-981.58K	-54.20%
Sep 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.4%	848.4K	122.18M	-153.2K	-15.30%
Sep 30, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.73%	1.54M	222.4M	462.27K	+42.72%
Sep 30, 2025	BAKER BROS. ADVISORS LP	3.17%	6.7M	965.37M	-1.01M	-13.09%
Sep 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	3.27%	6.93M	998.2M	-4.3M	-38.28%
Sep 30, 2025	AMERIPRISE FINANCIAL INC	1.29%	2.72M	391.98M	-236.09K	-7.98%
Sep 30, 2025	RTW INVESTMENTS, LP	1.46%	3.08M	444.21M	0	0
Sep 30, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.11%	206.65K	29.76M	-42.41K	-17.03%
Sep 30, 2025	LEGAL & GENERAL GROUP PLC	0.11%	208.02K	29.96M	170	+0.08%
Sep 30, 2025	RHUMBLINE ADVISERS	0.11%	212.9K	30.66M	4.56K	+2.19%
Sep 30, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.12%	219.84K	31.66M	-187.84K	-46.08%
Sep 30, 2025	ALLSPRING GLOBAL INVESTMENTS HOLDINGS, LLC	0.12%	227.63K	33.53M	-76.68K	-25.20%
Sep 30, 2025	ABRDN PLC	0.12%	234.62K	33.79M	-75.13K	-24.25%
Sep 30, 2025	FIRST TRUST ADVISORS LP	0.13%	240.65K	34.66M	193.25K	+407.78%
Sep 30, 2025	EAGLE HEALTH INVESTMENTS LP	0.14%	271.6K	39.11M	-157K	-36.63%
Sep 30, 2025	PATIENT SQUARE CAPITAL LP	0.17%	326.4K	47M	-32.4K	-9.03%
Sep 30, 2025	FEDERATED HERMES, INC.	0.17%	328.22K	47.27M	219.84K	+202.83%
Sep 30, 2025	ENVESTNET ASSET MANAGEMENT INC	0.18%	342.79K	49.36M	-23.04K	-6.30%
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.19%	352.89K	50.82M	44.2K	+14.32%
Sep 30, 2025	VICTORY CAPITAL MANAGEMENT INC	0.19%	354.91K	51.11M	172.13K	+94.18%
Sep 30, 2025	SWISS NATIONAL BANK	0.2%	371.3K	53.47M	23.9K	+6.88%
Sep 30, 2025	ING GROEP NV	0.2%	373.5K	53.79M	373.5K	+100.00%
Sep 30, 2025	DIMENSIONAL FUND ADVISORS LP	0.2%	386.67K	55.67M	-25.07K	-6.09%
Sep 30, 2025	CANDRIAM S.C.A.	0.21%	397.59K	57.26M	-41.1K	-9.37%
Sep 30, 2025	TD ASSET MANAGEMENT INC	0.21%	398.26K	57.35M	3.06K	+0.77%
Sep 30, 2025	TIMESSQUARE CAPITAL MANAGEMENT, LLC	0.22%	425.09K	61.22M	-448.41K	-51.33%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.23%	433.34K	62.41M	-320.82K	-42.54%
Sep 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.24%	445.88K	64.21M	18.12K	+4.24%
Sep 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.24%	450K	64.8M	-25K	-5.26%
Sep 30, 2025	WESTFIELD CAPITAL MANAGEMENT CO LP	0.26%	487.93K	70.27M	-851.36K	-63.57%
Sep 30, 2025	LOOMIS SAYLES & CO L P	0.26%	492.3K	70.9M	-301.27K	-37.96%
Sep 30, 2025	NWI MANAGEMENT LP	0.54%	1.02M	147.03M	301K	+41.81%
Sep 30, 2025	CAPITAL INTERNATIONAL INVESTORS	3.57%	7.55M	1.09B	74.99K	+1.00%
Sep 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.54%	1.14M	163.94M	-412.8K	-26.57%
Sep 30, 2025	SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC	0.49%	1.04M	150.04M	32.91K	+3.26%
Sep 30, 2025	EVENTIDE ASSET MANAGEMENT, LLC	0.47%	1.01M	144.74M	-191.39K	-16.00%
Jun 30, 2025	AMERIPRISE FINANCIAL INC	1.56%	2.96M	297.69M	6.35K	+0.22%
Jun 30, 2025	MILLENNIUM MANAGEMENT LLC	1.12%	2.12M	213.53M	1.44M	+212.39%
Jun 30, 2025	WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC	0.88%	1.67M	167.63M	-647.62K	-28.00%
Jun 30, 2025	PRINCIPAL FINANCIAL GROUP INC	0.71%	1.35M	135.67M	-407.35K	-23.21%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0.65%	1.23M	123.46M	-126.26K	-9.33%
Jun 30, 2025	NORGES BANK	1.02%	1.93M	194.73M	1.93M	+100.00%
Jun 30, 2025		0.31%	588.99K	59.28M	-569.11K	-49.14%
Jun 30, 2025	ALYESKA INVESTMENT GROUP, L.P.	0.32%	603.7K	60.76M	-131.3K	-17.86%
Jun 30, 2025	LORD, ABBETT & CO. LLC	0.82%	1.55M	155.58M	195.27K	+14.46%
Jun 30, 2025	PERCEPTIVE ADVISORS LLC	0.34%	650.25K	65.44M	140.95K	+27.68%
Jun 30, 2025	NOVO HOLDINGS A/S	0.36%	680K	68.44M	-44.67K	-6.16%
Jun 30, 2025	POLAR CAPITAL HOLDINGS PLC	0.37%	697.96K	70.24M	-30.8K	-4.23%
Jun 30, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	0.37%	700.7K	70.52M	242.7K	+52.99%
Jun 30, 2025	FIERA CAPITAL CORP	0.4%	748.04K	75.28M	168.8K	+29.14%
Jun 30, 2025	ARTIA GLOBAL PARTNERS LP	0.4%	752.71K	75.75M	434.47K	+136.52%
Jun 30, 2025	MAVERICK CAPITAL LTD	0.42%	804.13K	80.93M	379.01K	+89.15%
Jun 30, 2025	SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC	0.53%	1.01M	101.54M	304.57K	+43.24%
Jun 30, 2025	FIL LTD	0.62%	1.17M	117.29M	-1.22M	-51.24%
Jun 30, 2025	EVENTIDE ASSET MANAGEMENT, LLC	0.63%	1.2M	120.41M	14.82K	+1.25%
Jun 30, 2025	ARTISAN PARTNERS LIMITED PARTNERSHIP	1.75%	3.31M	333.56M	97.07K	+3.02%
Jun 30, 2025	D. E. SHAW & CO., INC.	1.81%	3.42M	344.45B	2.69M	+365.74%
Jun 30, 2025	ORBIS ALLAN GRAY LTD	0.81%	1.52M	153.39M	1.52M	+100.00%
Jun 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.82%	1.55M	156.19M	-459.7K	-22.83%
Jun 30, 2025	INVESCO LTD.	1%	1.9M	190.85M	105.01K	+5.86%
Jun 30, 2025	FRANKLIN RESOURCES INC	1.24%	2.35M	236.52M	201.85K	+9.40%
Jun 30, 2025	MACQUARIE GROUP LTD	0.6%	1.13M	113.82M	-1.23M	-52.12%
Jun 30, 2025	JANE STREET GROUP, LLC	0.71%	1.35M	136.16M	1.23M	+985.93%
Jun 30, 2025	CLEARBRIDGE INVESTMENTS, LLC	0.75%	1.42M	143.37M	-404.17K	-22.10%
Jun 30, 2025	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.85%	1.6M	161.02M	50K	+3.23%
Jun 30, 2025	JANUS HENDERSON GROUP PLC	1.21%	2.29M	230.78M	747.72K	+48.38%
Jun 30, 2025	STATE STREET CORP	2.26%	4.28M	430.53M	-1.47M	-25.57%
Jun 30, 2025	WESTFIELD CAPITAL MANAGEMENT CO LP	0.71%	1.34M	134.79M	-67.32K	-4.79%
Jun 30, 2025	TIMESSQUARE CAPITAL MANAGEMENT, LLC	0.46%	873.49K	87.91M	-190.66K	-17.92%
Jun 30, 2025	GW&K INVESTMENT MANAGEMENT, LLC	0.67%	1.27M	128.25M	-103.41K	-7.51%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.69%	1.3M	130.79M	-303.09K	-18.91%
Jun 30, 2025	MORGAN STANLEY	0.55%	1.04M	105.05B	-15.87K	-1.50%
Jun 30, 2025	ALLIANCEBERNSTEIN L.P.	0.71%	1.34M	135.18B	-1.08M	-44.58%
Jun 30, 2025	CITADEL ADVISORS LLC	0.81%	1.53M	154.31B	1.16M	+309.08%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.96%	1.81M	182.25B	408.27K	+29.11%
Jun 30, 2025	JPMORGAN CHASE & CO	8.26%	15.64M	1.57B	9.28M	+146.09%
Jun 30, 2025	VANGUARD GROUP INC	9.32%	17.64M	1.78B	-623.63K	-3.41%
Jun 30, 2025	HOOD RIVER CAPITAL MANAGEMENT LLC	0.48%	899.6K	90.54M	-658.68K	-42.27%
Jun 30, 2025	NORTHERN TRUST CORP	0.51%	969.8K	97.6M	-714.04K	-42.41%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.53%	1M	100.8M	665.6K	+198.10%
Jun 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.25%	475K	47.8M	335K	+239.29%
Jun 30, 2025	HOLOCENE ADVISORS, LP	1.07%	2.02M	202.97M	-9.62K	-0.47%
Jun 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	1.51%	2.86M	287.78M	-587.49K	-17.04%
Jun 30, 2025	FMR LLC	2.69%	5.09M	512.59M	1.7M	+50.05%
Jun 30, 2025	LOOMIS SAYLES & CO L P	0.42%	793.57K	79.86M	-215.9K	-21.39%
Jun 30, 2025	CANDRIAM S.C.A.	0.23%	438.69K	44.15M	-16.72K	-3.67%
Jun 30, 2025	CASTLE HOOK PARTNERS LP	0.24%	452.66K	45.56M	452.66K	+100.00%
Jun 30, 2025	BAKER BROS. ADVISORS LP	4.07%	7.71M	776.23M	2.33M	+43.35%
Jun 30, 2025	DARWIN GLOBAL MANAGEMENT, LTD.	10.22%	19.34M	1.92B	3.95M	+25.63%
Jun 30, 2025	PALO ALTO INVESTORS LP	0.46%	865.11K	87.06M	-122.04K	-12.36%
Jun 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.61%	1.16M	116.71M	-62.93K	-5.15%
Jun 30, 2025	BANK OF NEW YORK MELLON CORP	0.63%	1.2M	120.51M	40.72K	+3.52%
Jun 30, 2025	DEEP TRACK CAPITAL, LP	0.92%	1.75M	176.12M	1.5M	+586.95%
Jun 30, 2025	MARSHALL WACE, LLP	0.59%	1.11M	112.05M	417.12K	+59.91%
Jun 30, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.57%	1.08M	108.9M	1.08M	+100.00%
Jun 30, 2025	BLACKROCK, INC.	5.89%	11.14M	1.12B	-4.91M	-30.57%
Jun 30, 2025	WEISS ASSET MANAGEMENT LP	0.18%	339.83K	34.2M	339.83K	+100.00%
Jun 30, 2025	CAPTION MANAGEMENT, LLC	0.15%	282.1K	28.39M	134.3K	+90.87%
Jun 30, 2025	LOS ANGELES CAPITAL MANAGEMENT LLC	0.17%	330.8K	33.29M	318.72K	+2,637.50%
Jun 30, 2025	SOFINNOVA INVESTMENTS, INC.	0.17%	313.92K	31.59M	9.67K	+3.18%
Jun 30, 2025	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.17%	313.05K	31.51M	310.38K	+11,594.17%
Jun 30, 2025	ABRDN PLC	0.16%	309.75K	31.17M	-26.61K	-7.91%
Jun 30, 2025	HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND	0.13%	250.1K	25.17M	250.1K	+100.00%
Jun 30, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.13%	249.06K	25.07M	-72.31K	-22.50%
Jun 30, 2025	SUVRETTA CAPITAL MANAGEMENT, LLC	0.13%	238.78K	24.03M	-1.25M	-84.00%
Jun 30, 2025	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.12%	226.14K	22.76M	211K	+1,393.38%
Jun 30, 2025	Y-INTERCEPT (HONG KONG) LTD	0.12%	224.3K	22.57M	224.3K	+100.00%
Jun 30, 2025	RAYMOND JAMES FINANCIAL INC	0.41%	784.55K	78.96M	375.61K	+91.85%
Jun 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.4%	754.16K	75.9B	292.5K	+63.36%
Jun 30, 2025	HRT FINANCIAL LP	0.39%	729.6K	73.43M	729.6K	+100.00%
Jun 30, 2025	NWI MANAGEMENT LP	0.38%	720K	72.46M	270K	+60.00%
Jun 30, 2025	JENNISON ASSOCIATES LLC	0.38%	715.61K	72.02M	-32.71K	-4.37%
Jun 30, 2025	ENSIGN PEAK ADVISORS, INC	0.3%	564.39K	56.8M	-25.01K	-4.24%
Jun 30, 2025	CORMORANT ASSET MANAGEMENT, LP	0.29%	540K	54.35M	15K	+2.86%
Jun 30, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	0.28%	525K	52.84M	9.1K	+1.76%
Jun 30, 2025	LONG FOCUS CAPITAL MANAGEMENT, LLC	0.27%	520.2K	52.35M	-110.6K	-17.53%
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	5.93%	11.23M	1.13B	-1.69M	-13.10%
Jun 30, 2025	CAPITAL INTERNATIONAL INVESTORS	3.95%	7.48M	752.67M	280.37K	+3.89%
Jun 30, 2025	RTW INVESTMENTS, LP	1.63%	3.08M	310.43M	70K	+2.32%
Jun 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.26%	490.67K	49.38M	490.67K	+100.00%
Jun 30, 2025	ALKEON CAPITAL MANAGEMENT LLC	0.26%	500K	50.32M	500K	+100.00%
Jun 30, 2025	BROWN ADVISORY INC	0.31%	579.85K	58.36M	-92.6K	-13.77%
Jun 30, 2025	DUQUESNE FAMILY OFFICE LLC	1.19%	2.25M	226.79M	884.39K	+64.60%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.76%	3.34M	336.26M	-948.03K	-22.11%
Mar 31, 2025	EVENTIDE ASSET MANAGEMENT, LLC	0.65%	1.18M	90.16M	80.68K	+7.33%
Mar 31, 2025	HOLOCENE ADVISORS, LP	1.12%	2.03M	154.6M	1.34M	+194.66%
Mar 31, 2025	AMERIPRISE FINANCIAL INC	1.63%	2.95M	225.17M	101.53K	+3.56%
Mar 31, 2025	FIL LTD	1.32%	2.39M	182.35M	-247.96K	-9.40%
Mar 31, 2025	ALLIANCEBERNSTEIN L.P.	1.34%	2.42M	184.89M	59.95K	+2.54%
Mar 31, 2025	DUQUESNE FAMILY OFFICE LLC	0.76%	1.37M	104.45M	775.58K	+130.69%
Mar 31, 2025	MORGAN STANLEY	0.59%	1.06M	80.84M	-291.71K	-21.59%
Mar 31, 2025	LOOMIS SAYLES & CO L P	0.56%	1.01M	77.01M	-165.33K	-14.07%
Mar 31, 2025	PALO ALTO INVESTORS LP	0.55%	987.15K	75.31M	-616.31K	-38.44%
Mar 31, 2025	JANE STREET GROUP, LLC	0.41%	742K	56.61M	7.5K	+1.02%
Mar 31, 2025	ALYESKA INVESTMENT GROUP, L.P.	0.41%	735K	56.07M	-200.78K	-21.46%
Mar 31, 2025	CLEARBRIDGE INVESTMENTS, LLC	1.01%	1.83M	139.51M	-49.72K	-2.65%
Mar 31, 2025	INVESCO LTD.	0.99%	1.79M	136.66M	775.23K	+76.30%
Mar 31, 2025	CAPITAL INTERNATIONAL INVESTORS	3.98%	7.2M	549.17M	81.49K	+1.15%
Mar 31, 2025	MACQUARIE GROUP LTD	1.31%	2.36M	180.21B	48.95K	+2.12%
Mar 31, 2025	WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC	1.28%	2.31M	176.48M	-120.23K	-4.94%
Mar 31, 2025	VANGUARD GROUP INC	10.1%	18.27M	1.39B	49.15K	+0.27%
Mar 31, 2025	PRINCIPAL FINANCIAL GROUP INC	0.97%	1.76M	133.92M	-62.27K	-3.43%
Mar 31, 2025	PICTET ASSET MANAGEMENT HOLDING SA	1.11%	2.01M	153.85M	53.61K	+2.74%
Mar 31, 2025	NORTHERN TRUST CORP	0.93%	1.68M	128.46M	-66.8K	-3.82%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.89%	1.6M	122.27M	56.05K	+3.62%
Mar 31, 2025	JANUS HENDERSON GROUP PLC	0.85%	1.55M	120.53M	99.72K	+6.90%
Mar 31, 2025	SUVRETTA CAPITAL MANAGEMENT, LLC	0.83%	1.49M	113.85M	-119.18K	-7.40%
Mar 31, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	0.82%	1.48M	112.68M	-505.76K	-25.51%
Mar 31, 2025	WESTFIELD CAPITAL MANAGEMENT CO LP	0.78%	1.41M	107.31M	468.06K	+49.87%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.78%	1.4M	107.01M	-317.43K	-18.45%
Mar 31, 2025	GW&K INVESTMENT MANAGEMENT, LLC	0.76%	1.38M	105.11M	242.33K	+21.34%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0.75%	1.35M	103.22M	245.33K	+22.15%
Mar 31, 2025	HOOD RIVER CAPITAL MANAGEMENT LLC	0.86%	1.56M	118.88M	32.66K	+2.14%
Mar 31, 2025	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.86%	1.55M	118.25M	0	0
Mar 31, 2025	BLACKROCK, INC.	8.87%	16.05M	1.22B	15.94K	+0.10%
Mar 31, 2025	DARWIN GLOBAL MANAGEMENT, LTD.	8.51%	15.4M	1.2B	2.44M	+18.81%
Mar 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	7.15%	12.92M	985.94M	219.13K	+1.72%
Mar 31, 2025	LORD, ABBETT & CO. LLC	0.75%	1.35M	103.04M	-106.62K	-7.32%
Mar 31, 2025	JPMORGAN CHASE & CO	3.51%	6.35M	484.75M	3.07M	+93.35%
Mar 31, 2025	STATE STREET CORP	3.18%	5.75M	438.46M	-358.86K	-5.88%
Mar 31, 2025	BAKER BROS. ADVISORS LP	2.98%	5.38M	410.49M	373.76K	+7.47%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.37%	4.29M	327.26M	201.59K	+4.93%
Mar 31, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	1.91%	3.45M	262.97M	1.8M	+109.21%
Mar 31, 2025	FMR LLC	1.88%	3.39M	258.96M	-1.46M	-30.10%
Mar 31, 2025	ARTISAN PARTNERS LIMITED PARTNERSHIP	1.78%	3.22M	245.45M	90.93K	+2.91%
Mar 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.68%	1.22M	93.27M	470.4K	+62.53%
Mar 31, 2025	FRANKLIN RESOURCES INC	1.19%	2.15M	163.89M	-11.82K	-0.55%
Mar 31, 2025		0.64%	1.16M	88.35M	1.16M	+100.00%
Mar 31, 2025	BANK OF NEW YORK MELLON CORP	0.64%	1.16M	88.25M	-281.72K	-19.58%
Mar 31, 2025	VESTAL POINT CAPITAL, LP	0.59%	1.08M	82.01M	175K	+19.44%
Mar 31, 2025	TIMESSQUARE CAPITAL MANAGEMENT, LLC	0.59%	1.06M	81.18M	379.76K	+55.49%
Mar 31, 2025	AMERICAN CENTURY COMPANIES INC	0.48%	872.12K	66.53M	59.34K	+7.30%
Mar 31, 2025	JENNISON ASSOCIATES LLC	0.41%	748.31K	57.09M	-25.5K	-3.30%
Mar 31, 2025	RTW INVESTMENTS, LP	1.67%	3.01M	229.98M	0	0
Mar 31, 2024	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	2.38%	3.45M	93.64M	-2.4M	-41.00%
Mar 31, 2024	FRANKLIN RESOURCES INC	2.46%	3.57M	96.77M	170.29K	+5.01%
Mar 31, 2024	MACQUARIE GROUP LTD	2.69%	3.9M	105.79M	-751.99K	-16.17%
Mar 31, 2024	WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC	2.91%	4.21M	114.35M	-41.97K	-0.99%
Mar 31, 2024	FMR LLC	6.44%	9.32M	252.82M	4.23M	+83.02%
Mar 31, 2024	BLACKROCK INC.	8.15%	11.8M	320.13M	307.42K	+2.68%
Mar 31, 2024	VANGUARD GROUP INC	10.02%	14.51M	393.64M	383.71K	+2.72%
Mar 31, 2024	GREAT POINT PARTNERS LLC	0.54%	775.59K	21.04M	549.67K	+243.31%
Mar 31, 2024	PICTET ASSET MANAGEMENT HOLDING SA	1.06%	1.53M	41.51M	-431.79K	-22.01%
Mar 31, 2024	CAPITAL INTERNATIONAL INVESTORS	1.12%	1.62M	43.97M	1.62M	+100.00%
Mar 31, 2024	RTW INVESTMENTS, LP	1.29%	1.87M	50.6M	0	0
Mar 31, 2024	SUVRETTA CAPITAL MANAGEMENT, LLC	1.4%	2.02M	54.88M	-661.49K	-24.64%
Mar 31, 2024	CAPTION MANAGEMENT, LLC	0.42%	609.7K	16.54M	595.6K	+4,224.11%
Mar 31, 2024	HUDSON BAY CAPITAL MANAGEMENT LP	0.43%	626.81K	17.01M	159.31K	+34.08%
Mar 31, 2024	EMERALD ADVISERS, LLC	0.44%	630.18K	17.1M	-300.67K	-32.30%
Mar 31, 2024	EVENTIDE ASSET MANAGEMENT, LLC	0.44%	635.19K	17.23M	0	0
Mar 31, 2024	AMERICAN CENTURY COMPANIES INC	0.49%	702.62K	19.06M	40.42K	+6.10%
Mar 31, 2024	TWO SIGMA ADVISERS, LP	0.49%	716.4K	19.44M	87.2K	+13.86%
Mar 31, 2024	FIL LTD	0.5%	720.25K	19.54M	28.81K	+4.17%
Mar 31, 2024	FRONTIER CAPITAL MANAGEMENT CO LLC	0.52%	747.33K	20.28M	747.33K	+100.00%
Mar 31, 2024	VESTAL POINT CAPITAL, LP	0.52%	750K	20.35M	-150K	-16.67%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.52%	753.61K	20.45M	-8.16K	-1.07%
Mar 31, 2024	CITADEL ADVISORS LLC	0.64%	927.56K	25.16M	-118.65K	-11.34%
Mar 31, 2024	CLEARBRIDGE INVESTMENTS, LLC	0.64%	930.41K	25.24M	930.41K	+100.00%
Mar 31, 2024	MORGAN STANLEY	0.65%	939.6K	25.49M	-595.14K	-38.78%
Mar 31, 2024	HOOD RIVER CAPITAL MANAGEMENT LLC	0.66%	962.5K	26.11M	56.68K	+6.26%
Mar 31, 2024	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	0.67%	972.31K	26.38M	76.37K	+8.52%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.69%	996.13K	27.02M	-47.7K	-4.57%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.78%	1.13M	30.57M	-1.67K	-0.15%
Mar 31, 2024	ASSENAGON ASSET MANAGEMENT S.A.	0.84%	1.21M	32.87M	927.04K	+325.83%
Mar 31, 2024	GW&K INVESTMENT MANAGEMENT, LLC	0.88%	1.27M	34.45M	-21.87K	-1.69%
Mar 31, 2024	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.9%	1.3M	35.27M	950K	+271.43%
Mar 31, 2024	MARSHALL WACE, LLP	0.92%	1.33M	36.08M	-109.72K	-7.62%
Mar 31, 2024	NORTHERN TRUST CORP	0.92%	1.34M	36.27M	-35.45K	-2.58%
Mar 31, 2024	NOVO HOLDINGS A/S	0.92%	1.34M	36.34M	0	0
Mar 31, 2024	FIRST TRUST ADVISORS LP	0.99%	1.44M	38.99M	1.34M	+1,398.12%
Mar 31, 2024	PRINCIPAL FINANCIAL GROUP INC	0.99%	1.44M	39.05M	79.72K	+5.86%
Mar 31, 2024	LOOMIS SAYLES & CO L P	1.03%	1.49M	40.47M	-839.71K	-36.02%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	1.42%	2.05M	55.65M	-305.55K	-12.96%
Mar 31, 2024	BELLEVUE GROUP AG	1.48%	2.14M	58.11M	-149.12K	-6.51%
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	1.48%	2.15M	58.23M	-1.42K	-0.07%
Mar 31, 2024	JANUS HENDERSON GROUP PLC	1.54%	2.23M	60.49M	826.37K	+58.90%
Mar 31, 2024	AMERIPRISE FINANCIAL INC	1.89%	2.74M	74.21M	452.85K	+19.84%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	2.18%	3.16M	85.85M	94.37K	+3.07%
Mar 31, 2024	PALO ALTO INVESTORS LP	3.05%	4.42M	120.01M	-1.09M	-19.75%
Mar 31, 2024	DEEP TRACK CAPITAL, LP	3.3%	4.78M	129.78M	-566.32K	-10.59%
Mar 31, 2024	STATE STREET CORP	4.08%	5.91M	160.21M	-24.81K	-0.42%
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	7.44%	10.77M	292.17M	5.6K	+0.05%
Mar 31, 2024	RHUMBLINE ADVISERS	0.14%	207.66K	5.63M	3.97K	+1.95%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.16%	232.68K	6.31M	20.65K	+9.74%
Mar 31, 2024	BNP PARIBAS ARBITRAGE, SNC	0.17%	239.98K	6.51M	18.41K	+8.31%
Mar 31, 2024	ALLY BRIDGE GROUP (NY) LLC	0.17%	250K	6.78M	250K	+100.00%
Mar 31, 2024	SWISS NATIONAL BANK	0.19%	268.4K	7.28M	-800	-0.30%
Mar 31, 2024	STEMPOINT CAPITAL LP	0.19%	272.45K	7.39M	98.87K	+56.96%
Mar 31, 2024	SCOUT INVESTMENTS, INC.	0.19%	275.67K	7.37M	-17.53K	-5.98%
Mar 31, 2024	JPMORGAN CHASE & CO	0.2%	289.53K	7.85M	-92.96K	-24.30%
Mar 31, 2024	PEREGRINE CAPITAL MANAGEMENT LLC	0.2%	290.17K	7.87M	86	+0.03%
Mar 31, 2024	WCM INVESTMENT MANAGEMENT, LLC	0.22%	320K	8.68M	24.67K	+8.35%
Mar 31, 2024	BLEICHROEDER LP	0.22%	325K	8.82M	0	0
Mar 31, 2024	CITIGROUP INC	0.23%	326.57K	8.86M	183.29K	+127.92%
Mar 31, 2024	RAFFERTY ASSET MANAGEMENT, LLC	0.23%	329.64K	8.94M	8.55K	+2.66%
Mar 31, 2024	ENSIGN PEAK ADVISORS, INC	0.24%	341.57K	9.27M	271.56K	+387.89%
Mar 31, 2024	C WORLDWIDE GROUP HOLDING A/S	0.24%	343.11K	9.31M	0	0
Mar 31, 2024	UBS GROUP AG	0.26%	381.06K	10.34M	80.88K	+26.94%
Mar 31, 2024	CANDRIAM S.C.A.	0.27%	390.2K	10.59M	80K	+25.79%
Mar 31, 2024	TD ASSET MANAGEMENT INC	0.3%	427.18K	11.59B	-36.35K	-7.84%
Mar 31, 2024	LONG FOCUS CAPITAL MANAGEMENT, LLC	0.3%	431.65K	11.71M	60K	+16.14%
Mar 31, 2024	EMERALD MUTUAL FUND ADVISERS TRUST	0.33%	484.71K	13.15M	-263.63K	-35.23%
Mar 31, 2024	PANAGORA ASSET MANAGEMENT INC	0.36%	514.83K	13.97M	85.83K	+20.01%
Mar 31, 2024	EAGLE ASSET MANAGEMENT INC	0.36%	524.37K	14.01M	-24.26K	-4.42%
Mar 31, 2024	BALYASNY ASSET MANAGEMENT L.P.	0.31%	450.39K	12.22M	-493.04K	-52.26%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.37%	537.23K	14.58M	160.02K	+42.42%
Mar 31, 2024	OCTAGON CAPITAL ADVISORS LP	0.79%	1.14M	30.93M	-144K	-11.22%
Mar 31, 2024	SIO CAPITAL MANAGEMENT, LLC	0.94%	1.36M	36.97M	501K	+58.14%
Dec 31, 2023	FMR LLC	3.56%	5.09M	157.79M	786.66K	+18.27%
Dec 31, 2023	PALO ALTO INVESTORS LP	3.86%	5.51M	170.81M	-377.77K	-6.41%
Dec 31, 2023	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	4.09%	5.85M	181.31M	-2.47M	-29.72%
Dec 31, 2023	STATE STREET CORP	4.15%	5.93M	183.77M	875.55K	+17.32%
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	7.53%	10.76M	333.57M	356.56K	+3.43%
Dec 31, 2023	BLACKROCK INC.	8.04%	11.49M	356.15M	1.1M	+10.60%
Dec 31, 2023	VANGUARD GROUP INC	9.89%	14.13M	437.75M	-219.99K	-1.53%
Dec 31, 2023	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.42%	600K	18.59M	0	0
Dec 31, 2023	TWO SIGMA ADVISERS, LP	0.44%	629.2K	19.5M	-196.2K	-23.77%
Dec 31, 2023	EVENTIDE ASSET MANAGEMENT, LLC	0.44%	635.19K	19.68M	0	0
Dec 31, 2023	FIRST LIGHT ASSET MANAGEMENT, LLC	0.45%	646.06K	20.02M	2.47K	+0.38%
Dec 31, 2023	D. E. SHAW & CO., INC.	0.45%	646.91K	20.05M	450.18K	+228.83%
Dec 31, 2023	AMERICAN CENTURY COMPANIES INC	0.46%	662.2K	20.52M	47.67K	+7.76%
Dec 31, 2023	FIL LTD	0.48%	691.43K	21.43M	-139.77K	-16.82%
Dec 31, 2023	EMERALD MUTUAL FUND ADVISERS TRUST	0.52%	748.34K	23.19M	3.61K	+0.48%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.53%	761.77K	23.61M	-101.75K	-11.78%
Dec 31, 2023	SIO CAPITAL MANAGEMENT, LLC	0.6%	861.7K	26.7M	861.7K	+100.00%
Dec 31, 2023	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	0.63%	895.95K	27.77M	39.75K	+4.64%
Dec 31, 2023	HOOD RIVER CAPITAL MANAGEMENT LLC	0.63%	905.82K	28.07M	905.82K	+100.00%
Dec 31, 2023	EMERALD ADVISERS, LLC	0.65%	930.85K	28.85M	-6.67K	-0.71%
Dec 31, 2023	BALYASNY ASSET MANAGEMENT L.P.	0.66%	943.43K	29.24M	862.06K	+1,059.35%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.73%	1.04M	32.35M	-165.2K	-13.66%
Dec 31, 2023	CITADEL ADVISORS LLC	0.73%	1.05M	32.42M	466.83K	+80.57%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.79%	1.13M	34.97M	28.63K	+2.60%
Dec 31, 2023	OCTAGON CAPITAL ADVISORS LP	0.9%	1.28M	39.79M	0	0
Dec 31, 2023	SAMLYN CAPITAL, LLC	0.9%	1.29M	39.88M	-94.19K	-6.82%
Dec 31, 2023	GW&K INVESTMENT MANAGEMENT, LLC	0.9%	1.29M	40.03M	-60.5K	-4.47%
Dec 31, 2023	NOVO HOLDINGS A/S	0.94%	1.34M	41.51M	0	0
Dec 31, 2023	PRINCIPAL FINANCIAL GROUP INC	0.95%	1.36M	42.13M	69.28K	+5.37%
Dec 31, 2023	NORTHERN TRUST CORP	0.96%	1.37M	42.53M	25.81K	+1.92%
Dec 31, 2023	JANUS HENDERSON GROUP PLC	0.98%	1.4M	43.48M	-511.71K	-26.72%
Dec 31, 2023	MARSHALL WACE, LLP	1.01%	1.44M	44.62M	874.01K	+154.48%
Dec 31, 2023	NORGES BANK	1.02%	1.45M	45.03M	1.45M	+100.00%
Dec 31, 2023	MORGAN STANLEY	1.07%	1.53M	47.56M	856.02K	+126.12%
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	1.12%	1.61M	49.74M	-569.83K	-26.20%
Dec 31, 2023	HOLOCENE ADVISORS, LP	1.13%	1.61M	50.04M	-193.63K	-10.71%
Dec 31, 2023	RTW INVESTMENTS, LP	1.31%	1.87M	57.8M	0	0
Dec 31, 2023		0.63%	900K	27.89M	900K	+100.00%
Dec 31, 2023	ALLIANCEBERNSTEIN L.P.	1.5%	2.15M	66.56M	-146.89K	-6.40%
Dec 31, 2023	AMERIPRISE FINANCIAL INC	1.6%	2.28M	70.73M	405.78K	+21.62%
Dec 31, 2023	BELLEVUE GROUP AG	1.6%	2.29M	71M	-871.78K	-27.56%
Dec 31, 2023	LOOMIS SAYLES & CO L P	1.63%	2.33M	72.25M	-51.53K	-2.16%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	1.65%	2.36M	73.04M	-174.86K	-6.91%
Dec 31, 2023	SUVRETTA CAPITAL MANAGEMENT, LLC	1.88%	2.68M	83.19M	-761.85K	-22.11%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	2.15%	3.07M	95.13M	195.68K	+6.81%
Dec 31, 2023	FRANKLIN RESOURCES INC	2.38%	3.4M	105.26M	-15.11K	-0.44%
Dec 31, 2023	WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC	2.98%	4.26M	131.91M	14.75K	+0.35%
Dec 31, 2023	MACQUARIE GROUP LTD	3.26%	4.65M	144.15M	-2.28K	-0.05%
Dec 31, 2023	DEEP TRACK CAPITAL, LP	3.74%	5.35M	165.8M	-650K	-10.83%

Insiders

Insiders	Designation	Shares Held
LEWIS WILLIAM	Chair and CEO	301.19K
SHAROKY MELVIN MD	director	243.95K
WISE JOHN DRAYTON	Chief Commercial Officer	133.02K
ADSETT ROGER	Chief Operating Officer	106.81K
MCGIRR DAVID W J	director	97.72K
FLAMMER MARTINA M.D.	Chief Medical Officer	83.24K
BONSTEIN SARA	Chief Financial Officer	79.76K
ANDERSON ELIZABETH M	director	58.73K
LEE LEO	director	54.68K
SMITH MICHAEL ALEXANDER	Chief Legal Officer	51.87K
SCHAEFFER ORLOV S NICOLE	Chief People Strategy Officer	41.75K
DESJARDINS CLARISSA	director	3.03K

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Mar 05, 2026	LEWIS WILLIAM	SALE	147.54	2.13K	313.97K	301.19K
Feb 24, 2026	SMITH MICHAEL ALEXANDER	SALE	156.53	15.77K	2.47M	51.87K
Feb 19, 2026	LEWIS WILLIAM	SALE	153.38	1.03K	157.98K	301.19K
Feb 09, 2026	LEWIS WILLIAM	SALE	148.83	1.29K	191.54K	301.19K
Feb 05, 2026	FLAMMER MARTINA M.D.	SALE	152.44	869	132.47K	83.24K
Feb 03, 2026	LEWIS WILLIAM	SALE	156.34	3.01K	470.43K	303.88K
Feb 03, 2026	BONSTEIN SARA	SALE	156.34	748	116.94K	79.76K
Feb 03, 2026	FLAMMER MARTINA M.D.	SALE	155.77	795	123.84K	84.11K
Feb 03, 2026	ADSETT ROGER	SALE	156.17	791	123.53K	106.81K
Feb 03, 2026	SMITH MICHAEL ALEXANDER	SALE	156.27	640	100.01K	56.4K
Feb 02, 2026	FLAMMER MARTINA M.D.	SALE	156.86	100	15.69K	84.91K
Jan 20, 2026	LEWIS WILLIAM	SALE	160.70	254	40.82K	306.89K
Jan 12, 2026	LEWIS WILLIAM	SALE	174.86	315	55.08K	306.89K
Jan 09, 2026	FLAMMER MARTINA M.D.	SALE	186.19	1.89K	351.34K	84.91K
Jan 08, 2026	LEWIS WILLIAM	SALE	174.17	3.22K	561.35K	315.41K
Jan 08, 2026	FLAMMER MARTINA M.D.	SALE	174.17	3.25K	566.23K	86.79K
Jan 08, 2026	ADSETT ROGER	SALE	174.17	2.06K	358.62K	107.6K
Jan 08, 2026	SMITH MICHAEL ALEXANDER	SALE	174.17	1.05K	183.4K	57.04K
Jan 08, 2026	BONSTEIN SARA	SALE	174.17	1.45K	252.02K	80.51K
Jan 07, 2026	LEWIS WILLIAM	SALE	175.07	2.36K	412.64K	318.63K
Jan 07, 2026	ADSETT ROGER	SALE	175.07	802	140.41K	109.66K
Jan 07, 2026	SMITH MICHAEL ALEXANDER	SALE	175.07	709	124.12K	58.09K
Jan 07, 2026	BONSTEIN SARA	SALE	175.07	1.68K	293.77K	81.95K
Jan 07, 2026	FLAMMER MARTINA M.D.	SALE	175.84	1.43K	252.15K	91.71K
Jan 06, 2026	FLAMMER MARTINA M.D.	SALE	173.33	1.62K	279.93K	93.14K
Jan 06, 2026	LEWIS WILLIAM	SALE	173.33	4.1K	709.96K	320.99K
Jan 06, 2026	BONSTEIN SARA	SALE	173.33	1.52K	262.94K	83.63K
Jan 06, 2026	ADSETT ROGER	SALE	173.33	1.43K	247.69K	110.46K
Jan 06, 2026	SMITH MICHAEL ALEXANDER	SALE	173.33	1.4K	241.97K	58.8K
Jan 05, 2026	FLAMMER MARTINA M.D.	SALE	175.73	702	123.36K	94.75K
Jan 02, 2026	SCHAEFFER ORLOV S NICOLE	SALE	177.78	200	35.56K	41.75K
Dec 18, 2025	LEWIS WILLIAM	SALE	171.20	51	8.73K	303.91K
Dec 05, 2025	SHAROKY MELVIN MD	SALE	205.01	20K	4.1M	243.95K
Dec 04, 2025	LEWIS WILLIAM	SALE	207.42	1.04K	215.72K	303.91K
Dec 01, 2025	FLAMMER MARTINA M.D.	SALE	207.03	5.89K	1.22M	84.67K
Nov 24, 2025	ANDERSON ELIZABETH M	SALE	204.58	5K	1.02M	58.73K
Nov 17, 2025	LEE LEO	SALE	197.40	15.17K	3M	54.68K
Nov 14, 2025	ANDERSON ELIZABETH M	SALE	195.87	10K	1.96M	63.73K
Nov 12, 2025	SCHAEFFER ORLOV S NICOLE	SALE	195.88	164	32.12K	36.46K
Nov 11, 2025	FLAMMER MARTINA M.D.	SALE	191.04	2.91K	556.5K	83.11K
Nov 03, 2025	SMITH MICHAEL ALEXANDER	SALE	187.97	1.4K	263.16K	54.9K
Sep 12, 2025	SHAROKY MELVIN MD	SALE	145.39	10K	1.45M	262.68K
Sep 12, 2025	SCHAEFFER ORLOV S NICOLE	SALE	147.46	6.16K	908.06K	36.46K
Sep 02, 2025	SMITH MICHAEL ALEXANDER	SALE	145.89	1.18K	172.59K	54.9K
Sep 02, 2025	FLAMMER MARTINA M.D.	SALE	146.05	34.62K	5.06M	83.11K
Aug 20, 2025	SHAROKY MELVIN MD	SALE	129.50	10K	1.3M	274.52K
Aug 19, 2025	ADSETT ROGER	SALE	128.27	4.81K	616.59K	105.64K
Aug 18, 2025	LEWIS WILLIAM	SALE	129.47	1.42K	183.33K	233.92K
Aug 14, 2025	SCHAEFFER ORLOV S NICOLE	SALE	128.16	700	89.71K	79.76K
Aug 12, 2025	SHAROKY MELVIN MD	SALE	121.58	10K	1.22M	290.62K
Aug 04, 2025	FLAMMER MARTINA M.D.	SALE	109.50	8.72K	954.29K	83.11K
Aug 04, 2025	LEWIS WILLIAM	SALE	110.91	1.94K	214.94K	233.92K
Jul 21, 2025	BONSTEIN SARA	SALE	103.03	26.31K	2.71M	73.51K
Jul 15, 2025	SMITH MICHAEL ALEXANDER	SALE	102.51	933	95.64K	66.39K
Jul 15, 2025	LEWIS WILLIAM	SALE	103.32	170	17.56K	233.92K
Jul 11, 2025	SMITH MICHAEL ALEXANDER	SALE	96.41	748	72.11K	67.33K
Jul 07, 2025	BONSTEIN SARA	SALE	96.19	22.18K	2.13M	84.02K
Jul 01, 2025	LEWIS WILLIAM	SALE	99.61	815	81.18K	233.92K
Jun 23, 2025	BONSTEIN SARA	SALE	102.15	8.66K	884.72K	93.54K
Jun 16, 2025	ADSETT ROGER	SALE	99.32	4.19K	415.75K	130.64K
Jun 16, 2025	LEWIS WILLIAM	SALE	101.23	41.78K	4.23M	233.92K
Jun 11, 2025	SCHAEFFER ORLOV S NICOLE	SALE	96.02	500	48.01K	89.41K
Jun 11, 2025	FLAMMER MARTINA M.D.	SALE	94.50	19.42K	1.84M	83.11K
Jun 10, 2025	BONSTEIN SARA	SALE	91.66	100	9.17K	103.41K
Jun 10, 2025	SCHAEFFER ORLOV S NICOLE	SALE	88.64	38.3K	3.39M	118.58K
Jun 10, 2025	FLAMMER MARTINA M.D.	SALE	88.64	25.74K	2.28M	83.11K
Jun 05, 2025	SMITH MICHAEL ALEXANDER	SALE	73.50	1.88K	138.11K	67.72K
Jun 04, 2025	MCGIRR DAVID W J	SALE	73.27	3K	219.81K	97.72K
Jun 03, 2025	SCHAEFFER ORLOV S NICOLE	SALE	71.50	1.64K	117.4K	118.58K
Jun 03, 2025	MCGIRR DAVID W J	SALE	71.30	3.25K	231.73K	100.72K
Jun 03, 2025	LEWIS WILLIAM	SALE	71.50	5.47K	391.25K	308.76K
Jun 03, 2025	FLAMMER MARTINA M.D.	SALE	71.50	1.69K	120.55K	83.11K
Jun 03, 2025	BONSTEIN SARA	SALE	71.50	1.58K	112.9K	113.29K
Jun 03, 2025	ADSETT ROGER	SALE	71.50	1.86K	132.99K	141.32K
Jun 03, 2025	SMITH MICHAEL ALEXANDER	SALE	71.50	1.45K	103.53K	69.6K
Jun 02, 2025	LEWIS WILLIAM	SALE	71.94	1.43K	102.87K	233.92K
May 30, 2025	SMITH MICHAEL ALEXANDER	SALE	70.00	20K	1.4M	71.05K
May 21, 2025	DESJARDINS CLARISSA	PURCHASE	66.35	1.13K	74.98K	3.03K
May 20, 2025	DESJARDINS CLARISSA	PURCHASE	66.87	1.9K	126.72K	1.9K
May 20, 2025	LEWIS WILLIAM	SALE	68.54	1.72K	117.61K	233.92K
May 16, 2025	FLAMMER MARTINA M.D.	SALE	67.53	1.8K	121.49K	84.8K
May 15, 2025	FLAMMER MARTINA M.D.	SALE	65.47	9.93K	649.79K	86.6K
May 14, 2025	BONSTEIN SARA	SALE	65.61	1.63K	107.21K	108.36K
May 14, 2025	ADSETT ROGER	SALE	65.61	1.93K	126.3K	136.68K
May 14, 2025	LEWIS WILLIAM	SALE	65.61	3.77K	247.42K	312.97K
May 14, 2025	SMITH MICHAEL ALEXANDER	SALE	65.61	409	26.83K	91.79K
May 14, 2025	FLAMMER MARTINA M.D.	SALE	65.61	1.74K	114.42K	90.01K
May 14, 2025	SCHAEFFER ORLOV S NICOLE	SALE	65.61	1.24K	81.09K	114.64K
May 13, 2025	ADSETT ROGER	SALE	67.81	7.48K	507.35K	138.6K
May 13, 2025	SCHAEFFER ORLOV S NICOLE	SALE	67.81	5K	338.98K	115.88K
May 13, 2025	SMITH MICHAEL ALEXANDER	SALE	67.81	4.41K	298.84K	92.2K
May 13, 2025	BONSTEIN SARA	SALE	67.81	8.87K	601.47K	109.99K
May 13, 2025	FLAMMER MARTINA M.D.	SALE	67.81	8.41K	570.15K	91.76K
May 13, 2025	LEWIS WILLIAM	SALE	67.70	7.7K	521.22K	316.74K
May 01, 2025	LEWIS WILLIAM	SALE	72.78	4.2K	305.75K	233.92K
Apr 15, 2025	LEWIS WILLIAM	SALE	71.30	600	42.78K	233.92K
Apr 01, 2025	LEWIS WILLIAM	SALE	75.26	805	60.58K	233.92K
Mar 17, 2025	LEWIS WILLIAM	SALE	77.83	2.74K	213.02K	233.92K
Mar 03, 2025	LEWIS WILLIAM	SALE	80.90	46	3.72K	233.92K
Feb 18, 2025	BONSTEIN SARA	SALE	81.00	700	56.7K	118.86K
Feb 18, 2025	LEWIS WILLIAM	SALE	81.81	300	24.54K	233.92K
Feb 12, 2025	BONSTEIN SARA	SALE	80.00	5.02K	401.52K	137.19K
Feb 11, 2025	BONSTEIN SARA	SALE	80.00	13.3K	1.06M	142.2K
Feb 10, 2025	ADSETT ROGER	SALE	79.33	26.14K	2.07M	146.08K
Feb 10, 2025	FLAMMER MARTINA M.D.	SALE	79.33	23.01K	1.83M	100.17K
Feb 07, 2025	FLAMMER MARTINA M.D.	SALE	79.59	60	4.78K	137.99K
Feb 07, 2025	WISE JOHN DRAYTON	SALE	78.91	10	789.1	133.02K
Feb 07, 2025	ADSETT ROGER	SALE	79.57	100	7.96K	189.06K
Feb 06, 2025	SCHAEFFER ORLOV S NICOLE	SALE	80.90	23.5K	1.9M	120.88K
Feb 06, 2025	ADSETT ROGER	SALE	80.90	45.61K	3.69M	189.16K
Feb 06, 2025	WISE JOHN DRAYTON	SALE	80.90	7.91K	639.92K	133.03K
Feb 06, 2025	LEWIS WILLIAM	SALE	80.90	79.35K	6.42M	453.89K
Feb 06, 2025	BONSTEIN SARA	SALE	80.90	28.39K	2.3M	155.51K
Feb 06, 2025	FLAMMER MARTINA M.D.	SALE	80.90	33.06K	2.67M	138.05K
Feb 06, 2025	SMITH MICHAEL ALEXANDER	SALE	80.90	20.65K	1.67M	96.61K
Feb 03, 2025	LEWIS WILLIAM	SALE	78.40	2.58K	202.35K	233.92K
Jan 30, 2025	SCHAEFFER ORLOV S NICOLE	SALE	80.00	91.14K	7.29M	97.08K
Jan 15, 2025	LEWIS WILLIAM	SALE	71.01	631	44.81K	233.92K
Jan 14, 2025	FLAMMER MARTINA M.D.	SALE	68.72	1.38K	95.11K	100.17K
Jan 14, 2025	SCHAEFFER ORLOV S NICOLE	SALE	68.72	872	59.92K	97.08K
Jan 14, 2025	ADSETT ROGER	SALE	68.72	1.46K	100.13K	146.08K
Jan 10, 2025	FLAMMER MARTINA M.D.	SALE	63.62	4.8K	305.44K	101.55K
Jan 10, 2025	ADSETT ROGER	SALE	63.62	3.6K	229.29K	147.54K
Jan 10, 2025	SCHAEFFER ORLOV S NICOLE	SALE	63.62	3.09K	196.71K	97.96K
Jan 10, 2025	WISE JOHN DRAYTON	SALE	65.40	287	18.77K	125.56K
Jan 10, 2025	LEWIS WILLIAM	SALE	63.36	2.98K	188.69K	392.59K
Jan 10, 2025	SMITH MICHAEL ALEXANDER	SALE	63.38	319	20.22K	69.97K
Jan 10, 2025	BONSTEIN SARA	SALE	63.72	1.07K	67.93K	118.86K
Jan 08, 2025	WISE JOHN DRAYTON	SALE	66.21	392	25.95K	119.19K
Jan 08, 2025	FLAMMER MARTINA M.D.	SALE	66.16	1.7K	112.6K	101.06K
Jan 08, 2025	SCHAEFFER ORLOV S NICOLE	SALE	65.84	1.21K	79.6K	96.31K
Jan 08, 2025	ADSETT ROGER	SALE	66.10	1.88K	124.4K	145.78K
Jan 08, 2025	LEWIS WILLIAM	SALE	65.96	4K	263.77K	372.74K
Jan 08, 2025	BONSTEIN SARA	SALE	66.05	1.46K	96.7K	113.27K
Jan 08, 2025	SMITH MICHAEL ALEXANDER	SALE	66.21	1.06K	70.45K	64.58K
Jan 07, 2025	ADSETT ROGER	SALE	65.95	2.44K	161.18K	147.67K
Jan 07, 2025	LEWIS WILLIAM	SALE	66.02	8.22K	542.55K	376.74K
Jan 07, 2025	SMITH MICHAEL ALEXANDER	SALE	65.98	2.31K	152.15K	65.64K
Jan 07, 2025	WISE JOHN DRAYTON	SALE	65.87	2.91K	191.55K	119.58K
Jan 07, 2025	FLAMMER MARTINA M.D.	SALE	65.91	3.34K	220.4K	102.77K
Jan 07, 2025	SCHAEFFER ORLOV S NICOLE	SALE	65.88	2.6K	171.02K	97.52K
Jan 07, 2025	BONSTEIN SARA	SALE	65.70	3.47K	227.98K	114.74K
Jan 02, 2025	LEWIS WILLIAM	SALE	69.86	6.83K	477.14K	233.92K
Dec 19, 2024	LEWIS WILLIAM	SALE	70.61	1.59K	112.27K	233.92K
Dec 12, 2024	LEWIS WILLIAM	SALE	74.22	181	13.43K	233.92K
Sep 16, 2024	FLAMMER MARTINA M.D.	SALE	74.92	13.44K	1.01M	106.13K
Sep 13, 2024	SMITH MICHAEL ALEXANDER	SALE	74.75	9K	672.75K	67.86K
Sep 13, 2024	FLAMMER MARTINA M.D.	SALE	74.90	26.97K	2.02M	106.13K
Sep 10, 2024	SCHAEFFER ORLOV S NICOLE	SALE	71.88	9.58K	688.75K	100.1K
Sep 06, 2024	FLAMMER MARTINA M.D.	SALE	72.61	9.06K	658.14K	106.13K
Aug 12, 2024	SMITH MICHAEL ALEXANDER	SALE	73.65	20.42K	1.5M	88.73K
Aug 12, 2024	SCHAEFFER ORLOV S NICOLE	SALE	72.49	9.47K	686.41K	100.1K
Jun 10, 2024	FLAMMER MARTINA M.D.	SALE	60.00	21.2K	1.27M	106.13K
Jun 03, 2024	SCHAEFFER ORLOV S NICOLE	SALE	55.33	55K	3.04M	108.76K
May 30, 2024	FLAMMER MARTINA M.D.	SALE	55.00	21.2K	1.17M	106.13K
May 29, 2024	BONSTEIN SARA	SALE	50.00	220.56K	11.03M	117.48K
May 28, 2024	SMITH MICHAEL ALEXANDER	SALE	49.53	44.72K	2.22M	88.83K
May 28, 2024	SCHAEFFER ORLOV S NICOLE	SALE	49.53	27.5K	1.36M	108.76K
May 28, 2024	FLAMMER MARTINA M.D.	SALE	49.62	103.81K	5.15M	106.13K
May 28, 2024	WISE JOHN DRAYTON	SALE	50.00	6.25K	312.5K	121.66K
May 28, 2024	BONSTEIN SARA	SALE	50.01	20.72K	1.04M	338.05K
May 17, 2024	ADSETT ROGER	SALE	25.09	5.95K	149.16K	149.28K
May 17, 2024	FLAMMER MARTINA M.D.	SALE	25.09	4.64K	116.47K	106.13K
May 14, 2024	SCHAEFFER ORLOV S NICOLE	SALE	25.53	6.51K	166.15K	108.76K
May 14, 2024	SMITH MICHAEL ALEXANDER	SALE	25.40	5.09K	129.36K	94.58K
May 14, 2024	FLAMMER MARTINA M.D.	SALE	25.47	10.64K	271K	110.78K
May 14, 2024	WISE JOHN DRAYTON	SALE	25.47	5.09K	129.59K	123.26K
May 14, 2024	LEWIS WILLIAM	SALE	25.52	22.2K	566.49K	384.13K
May 14, 2024	BONSTEIN SARA	SALE	25.32	11.09K	280.75K	117.48K
May 14, 2024	ADSETT ROGER	SALE	25.50	7.86K	200.35K	155.22K
Jan 12, 2024	ADSETT ROGER	SALE	28.63	5.25K	150.34K	148.56K
Jan 12, 2024	FLAMMER MARTINA M.D.	SALE	28.63	4.67K	133.62K	106.9K
Jan 10, 2024	ADSETT ROGER	SALE	28.90	3.54K	102.19K	153.81K
Jan 10, 2024	FLAMMER MARTINA M.D.	SALE	28.90	1.25K	35.98K	111.57K
Jan 09, 2024	LEWIS WILLIAM	SALE	28.72	9.89K	283.95K	363.65K
Jan 09, 2024	FLAMMER MARTINA M.D.	SALE	29.01	4.72K	136.78K	112.81K
Jan 09, 2024	ADSETT ROGER	SALE	29.25	3.84K	112.23K	157.35K
Jan 09, 2024	BONSTEIN SARA	SALE	29.18	4.5K	131.22K	114.05K
Jan 09, 2024	SCHAEFFER ORLOV S NICOLE	SALE	28.74	3.17K	90.96K	101.98K
Jan 09, 2024	WISE JOHN DRAYTON	SALE	28.78	1.86K	53.56K	113.83K
Jan 09, 2024	SMITH MICHAEL ALEXANDER	SALE	28.76	2.37K	68.25K	86.36K
Jan 08, 2024	LEWIS WILLIAM	SALE	29.88	20.17K	602.65K	373.54K
Jan 05, 2024	LEWIS WILLIAM	SALE	29.26	6.98K	204.2K	373.54K
Jan 05, 2024	WISE JOHN DRAYTON	SALE	29.32	1.17K	34.22K	115.69K
Jan 05, 2024	SCHAEFFER ORLOV S NICOLE	SALE	29.28	1.46K	42.66K	105.15K
Jan 05, 2024	ADSETT ROGER	SALE	29.21	3.04K	88.86K	161.18K
Jan 05, 2024	FLAMMER MARTINA M.D.	SALE	29.20	1.39K	40.48K	117.53K
Jan 05, 2024	SMITH MICHAEL ALEXANDER	SALE	29.30	627	18.37K	88.74K
Jan 03, 2024	WISE JOHN DRAYTON	SALE	29.19	20.07K	585.87K	103.98K
Dec 28, 2023	SCHAEFFER ORLOV S NICOLE	SALE	32.00	22.29K	713.22K	94.55K
Dec 22, 2023	FLAMMER MARTINA M.D.	SALE	30.00	28.31K	849.3K	106.04K
Dec 22, 2023	BONSTEIN SARA	SALE	30.00	13.2K	395.97K	105.24K
Oct 27, 2023	LEWIS WILLIAM	SALE	25.08	1.32K	33.16K	0
Jul 11, 2023	SMITH MICHAEL ALEXANDER	SALE	20.18	740	14.93K	77.14K
Jun 13, 2023	FLAMMER MARTINA M.D.	SALE	19.27	8.87K	170.89K	106.04K
Jun 13, 2023	ADSETT ROGER	SALE	19.32	8.98K	173.51K	151.35K
May 25, 2023	WISE JOHN DRAYTON	SALE	18.95	3.37K	63.79K	102.68K
May 17, 2023	SMITH MICHAEL ALEXANDER	SALE	18.18	1.26K	22.96K	77.08K
May 17, 2023	LEWIS WILLIAM	SALE	18.12	7.1K	128.63K	341.35K
May 17, 2023	SCHAEFFER ORLOV S NICOLE	SALE	18.16	1.97K	35.81K	93.53K
May 17, 2023	WISE JOHN DRAYTON	SALE	18.17	1.91K	34.76K	106.05K
May 17, 2023	ADSETT ROGER	SALE	18.12	2.45K	44.36K	160.33K
May 16, 2023	SCHAEFFER ORLOV S NICOLE	SALE	18.45	1.22K	22.45K	95.5K
May 16, 2023	ADSETT ROGER	SALE	18.39	1.52K	27.97K	162.78K
May 16, 2023	BONSTEIN SARA	SALE	18.47	1.61K	29.74K	117.62K
May 16, 2023	SMITH MICHAEL ALEXANDER	SALE	18.43	475	8.75K	78.35K
May 16, 2023	LEWIS WILLIAM	SALE	18.41	3.71K	68.37K	348.44K
May 16, 2023	FLAMMER MARTINA M.D.	SALE	18.43	1.72K	31.66K	114.91K
May 16, 2023	WISE JOHN DRAYTON	SALE	18.44	381	7.03K	107.96K
May 15, 2023	FLAMMER MARTINA M.D.	SALE	19.28	2.58K	49.67K	116.62K
May 15, 2023	SCHAEFFER ORLOV S NICOLE	SALE	19.22	1.83K	35.17K	96.71K
May 15, 2023	SHAROKY MELVIN MD	PURCHASE	19.29	10K	192.9K	10K
May 15, 2023	ADSETT ROGER	SALE	19.27	2.85K	54.86K	164.3K
May 15, 2023	SMITH MICHAEL ALEXANDER	SALE	19.24	1.9K	36.5K	78.82K
May 15, 2023	WISE JOHN DRAYTON	SALE	19.29	593	11.44K	108.34K
May 15, 2023	LEWIS WILLIAM	SALE	19.23	6.05K	116.3K	352.16K
May 15, 2023	BONSTEIN SARA	SALE	19.30	2.21K	42.65K	119.23K
Jan 10, 2023	BONSTEIN SARA	SALE	18.12	2.86K	51.77K	66.03K
Jan 10, 2023	WISE JOHN DRAYTON	SALE	17.96	779	13.99K	77.27K
Jan 10, 2023	ADSETT ROGER	SALE	17.99	3.19K	57.46K	135.49K
Jan 10, 2023	SMITH MICHAEL ALEXANDER	SALE	17.93	1.84K	32.92K	54.33K
Jan 10, 2023	SCHAEFFER ORLOV S NICOLE	SALE	17.95	2.44K	43.71K	72.16K
Jan 10, 2023	LEWIS WILLIAM	SALE	18.00	6.99K	125.89K	265.07K
Jan 10, 2023	FLAMMER MARTINA M.D.	SALE	18.06	3.44K	62.11K	72.76K
Jan 05, 2023	ADSETT ROGER	SALE	19.75	3.04K	60.12K	131.08K
Jan 05, 2023	SMITH MICHAEL ALEXANDER	SALE	19.72	720	14.2K	49.84K
Jan 05, 2023	LEWIS WILLIAM	SALE	19.80	7.01K	138.76K	249.71K
Jan 05, 2023	SCHAEFFER ORLOV S NICOLE	SALE	19.73	1.45K	28.57K	68.26K
Jan 05, 2023	WISE JOHN DRAYTON	SALE	19.74	1.16K	22.9K	70.45K
Jan 05, 2023	FLAMMER MARTINA M.D.	SALE	19.73	1.37K	27.11K	65.06K
Nov 22, 2022	WISE JOHN DRAYTON	SALE	18.84	7.15K	134.78K	71.61K
Nov 22, 2022	ADSETT ROGER	SALE	18.80	11.86K	222.87K	134.13K
Nov 01, 2022	SHAROKY MELVIN MD	PURCHASE	17.70	10K	177K	15.9K
Oct 31, 2022	SHAROKY MELVIN MD	PURCHASE	17.53	20K	350.6K	281.02K
Oct 31, 2022	LEE LEO	PURCHASE	17.69	45K	796.05K	98.27K
Aug 10, 2022	WISE JOHN DRAYTON	SALE	27.79	258	7.17K	78.77K
Aug 08, 2022	LEWIS WILLIAM	SALE	27.75	161.19K	4.47M	0
Jul 12, 2022	SMITH MICHAEL ALEXANDER	SALE	23.40	941	22.02K	50.46K
Jul 07, 2022	LEWIS WILLIAM	SALE	23.00	96.61K	2.22M	256.72K
May 17, 2022	LEWIS WILLIAM	SALE	20.18	6K	121K	255.83K
May 16, 2022	ADSETT ROGER	SALE	18.45	1.39K	25.72K	148K
May 16, 2022	LEWIS WILLIAM	SALE	18.35	3.4K	62.35K	261.82K
May 16, 2022	SMITH MICHAEL ALEXANDER	SALE	20.37	1.06K	21.49K	50.58K
May 16, 2022	SCHAEFFER ORLOV S NICOLE	SALE	18.41	1.11K	20.51K	70.49K
May 16, 2022	FLAMMER MARTINA M.D.	SALE	18.51	1.57K	29.13K	66.43K
May 16, 2022	BONSTEIN SARA	SALE	18.51	1.43K	26.52K	54.68K
May 11, 2022	SHAROKY MELVIN MD	PURCHASE	17.20	20K	344K	262.62K
Mar 23, 2022	LEWIS WILLIAM	SALE	23.16	65.41K	1.51M	217.62K
Jan 12, 2022	ADSETT ROGER	SALE	24.58	1.22K	29.91K	121.94K
Jan 11, 2022	SCHAEFFER ORLOV S NICOLE	SALE	25.11	925	23.23K	56.96K
Jan 11, 2022	BONSTEIN SARA	SALE	25.11	1.15K	28.98K	35.98K
Jan 11, 2022	FLAMMER MARTINA M.D.	SALE	25.11	1.5K	37.54K	46.04K
Jan 11, 2022	LEWIS WILLIAM	SALE	25.11	2.87K	72.14K	217.62K
Jan 11, 2022	SMITH MICHAEL ALEXANDER	SALE	25.11	407	10.22K	37.43K
Jan 06, 2022	ADSETT ROGER	SALE	26.00	1.76K	45.73K	105.42K
Jan 06, 2022	LEWIS WILLIAM	SALE	26.00	5.34K	138.76K	189.76K
Jan 05, 2022	LEWIS WILLIAM	SALE	27.61	7.13K	196.75K	195.09K
Jan 05, 2022	ADSETT ROGER	SALE	27.61	3.07K	84.71K	107.18K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES120.22K41

NET SHARES-120.22K41

SHARES HELD5.85M41

% NET SHARES-102.05%0%

INSM Stock Ownership Breakdown

Insmed

Stock Outstanding Shares

Market Insider

Institutional Ownership

Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions

Stock Outstanding Shares

Market Insider

Institutional Ownership

Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions