How many institutions own ESPR stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own ESPR shares is 210, representing 50.62% of the company's common stock.

Who are the major shareholders selling Esperion Therapeutics, Inc. stock?

PRINCIPAL FINANCIAL GROUP INC, in the last quarter, reduced its stake in ESPR by -51.68% restricting it's holding to 190.06 thousand shares of worth nearly $503.65K. SIMPLEX TRADING, LLC also lessened -12.31% of the ESPR shares from its portfolio, reducing its holding to 202.09 thousand shares of worth $535.00K. TWO SEAS CAPITAL LP also shunned ESPR shares holding by -2.06% last quarter which brought its holding to 9.75 million shares worth $25.84M.

Investors who are buying ESPR stock?

As per its latest 13F filing, GEODE CAPITAL MANAGEMENT, LLC increased its stake in ESPR by 3.65% in the last quarter. The institutional holder raised its holding to 4.75 million shares having worth more than $12.59M. VOLEON CAPITAL MANAGEMENT LP also added 100% more shares of ESPR to its portfolio, raising its holding to 207.88 thousand shares of worth $550.88K. AQR CAPITAL MANAGEMENT LLC also increased its ESPR shares holding by 54.53% which brought its holding to 284.91 thousand shares worth $755.00K.

ESPR's major insiders: who are they?

The insider with the most stakes in ESPR is BIOTECH TARGET N V , 10 percent owner at the company. Additionally, ESPR stock is highly held by director JANNEY DANIEL and President and CEO Koenig Sheldon L. among others.

Did an insider recently sell ESPR stock?

Company executives, directors, and other insiders own 0.56% percent of Esperion Therapeutics, Inc.'s stock. Within the last six months, there have been 8 transaction(s) in which ESPR insiders have sold stock, totaling 105.15K shares. Insiders that have sold shares include KOENIG SHELDON L., HALLADAY BENJAMIN, and LOOKER BENJAMIN.

Which insider recently purchased ESPR stock?

There have been 0 transaction(s) during the past 6-months in which Esperion Therapeutics, Inc. insiders have bought stock, totalling 0 shares

How much of ESPR does insiders own?

Around 5.59M Esperion Therapeutics, Inc. shares are held by insiders, which represents about 0.56% of ESPR stock.

Who is the insider with the largest stake?

ESPR 10 percent owner, BIOTECH TARGET N V holds the largest portfolio of the company's shares. ESPR shares owned by BIOTECH total nearly 4.48 million.

Which institution holds the most shares in ESPR?

GEODE CAPITAL MANAGEMENT, LLC is the largest institutional owner in ESPR which holds 4.75 million shares worth $12.59M or 2.41% of the total ESPR shares outstanding followed by PENTWATER CAPITAL MANAGEMENT LP with ownership of 181.29 thousand shares representing 0.09% of the ESPR ownership. PRINCIPAL FINANCIAL GROUP INC is the third largest stakeholder with 190.06 thousand shares or 0.1% of the ownership worth more than $503.65K.

Is Esperion Therapeutics, Inc. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the ESPR is concerned, it is a stock which is optionable.

Is there a short position on ESPR's shares?

Number of ESPR shares short is 23.13M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding ESPR shares are there?

As of today, 201.62M shares of ESPR are outstanding.

Is there many float in ESPR stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, ESPR has 199.76M shares in float.

ESPR short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for ESPR is 4.77.

Esperion Therapeutics (ESPR) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares11.55

Short Percent Of Float11.6

Shares Outstanding201.62M

Shares Float199.76M

Shares Short23.13M

Short Ratio4.77

11.6%

Short % of Float

11.55%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

0.56% Percentage of Shares held by All Insiders

50.62% Percentage of Shares held by All Institutions

50.9% Percentage of Float held by Institutions

210

Number of Institutions Holding Shares

Institutional Ownership

About 50.62% of ESPR shares are held by financial institutions. GEODE CAPITAL MANAGEMENT, LLC is the top corporate investor, holding 4.75M shares valued at $12.59M. A 2.41% stake in Esperion Therapeutics, Inc. is owned by the company. PENTWATER CAPITAL MANAGEMENT LP owns 181.29K shares valued at $480.42K, which translates its holding of 0.09% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.41%	4.75M	12.59M	167.41K	+3.65%
Sep 30, 2025	PENTWATER CAPITAL MANAGEMENT LP	0.09%	181.29K	480.42K	0	0
Sep 30, 2025	PRINCIPAL FINANCIAL GROUP INC	0.1%	190.06K	503.65K	-203.23K	-51.68%
Sep 30, 2025	NJ STATE EMPLOYEES DEFERRED COMPENSATION PLAN	0.1%	195.13K	517.08K	0	0
Sep 30, 2025	SIMPLEX TRADING, LLC	0.1%	202.09K	535K	-28.37K	-12.31%
Sep 30, 2025	VOLEON CAPITAL MANAGEMENT LP	0.11%	207.88K	550.88K	207.88K	+100.00%
Sep 30, 2025	TWO SEAS CAPITAL LP	4.95%	9.75M	25.84M	-205.25K	-2.06%
Sep 30, 2025	AQR CAPITAL MANAGEMENT LLC	0.14%	284.91K	755K	100.54K	+54.53%
Sep 30, 2025	ROYAL BANK OF CANADA	0.46%	909.23K	2.41M	-257.29K	-22.06%
Sep 30, 2025	UBS GROUP AG	0.63%	1.25M	3.3M	-290.9K	-18.92%
Sep 30, 2025	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.76%	1.5M	3.98M	1.5M	+100.00%
Sep 30, 2025	NORTHERN TRUST CORP	0.94%	1.85M	4.9M	64.31K	+3.60%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	0.87%	1.71M	4.53M	910.05K	+113.93%
Sep 30, 2025	ROYCE & ASSOCIATES LP	1.17%	2.29M	6.08M	2.29M	+100.00%
Sep 30, 2025	MARSHALL WACE, LLP	1.28%	2.52M	6.68M	-2.79M	-52.54%
Sep 30, 2025	AIGH CAPITAL MANAGEMENT LLC	1.52%	3M	7.95M	3M	+100.00%
Sep 30, 2025	DAVIDSON KEMPNER CAPITAL MANAGEMENT LP	0.11%	222.48K	589.58K	0	0
Sep 30, 2025	HIGHBRIDGE CAPITAL MANAGEMENT LLC	0.13%	254.27K	673.8K	0	0
Sep 30, 2025	BREVAN HOWARD CAPITAL MANAGEMENT LP	0.13%	263.28K	697.68K	184.56K	+234.47%
Sep 30, 2025	MACKENZIE FINANCIAL CORP	0.14%	272.96K	723.34K	261.26K	+2,232.97%
Sep 30, 2025	RHUMBLINE ADVISERS	0.14%	277.49K	735.34K	1.8K	+0.65%
Sep 30, 2025	SQUAREPOINT OPS LLC	0.15%	296.81K	786.55K	82.43K	+38.45%
Sep 30, 2025	MARINER, LLC	0.15%	302.51K	801.66K	302.51K	+100.00%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.15%	304.57K	807.12K	-531.77K	-63.58%
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.24%	463.09K	1.23M	36.03K	+8.44%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.3%	586.42K	1.55M	-30.72K	-4.98%
Sep 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.35%	681.29K	1.81M	681.29K	+100.00%
Sep 30, 2025	MILLENNIUM MANAGEMENT LLC	0.5%	974.86K	2.58M	522.21K	+115.37%
Sep 30, 2025	NUVEEN, LLC	1.89%	3.71M	9.83M	3.29M	+778.12%
Sep 30, 2025	VANGUARD GROUP INC	6.14%	12.09M	32.04M	375.62K	+3.21%
Sep 30, 2025	BLACKROCK, INC.	7.54%	14.83M	39.31M	120.73K	+0.82%
Sep 30, 2025	DIAMETRIC CAPITAL, LP	0.12%	236.15K	625.78K	-442.68K	-65.21%
Sep 30, 2025	CAPITAL ADVISORS WEALTH MANAGEMENT, LLC	0.02%	42.56K	112.77K	0	0
Sep 30, 2025	PRUDENTIAL FINANCIAL INC	0.02%	43.71K	115.83K	14.5K	+49.64%
Sep 30, 2025	SAVANT CAPITAL, LLC	0.02%	43.96K	116.48K	22.08K	+100.93%
Sep 30, 2025	BOOMFISH WEALTH GROUP, LLC	0.02%	45.31K	120.06K	0	0
Sep 30, 2025	LOS ANGELES CAPITAL MANAGEMENT LLC	0.02%	48.17K	127.66K	0	0
Sep 30, 2025	PRIVATE ADVISOR GROUP, LLC	0.03%	53.61K	142.06K	13.5K	+33.66%
Sep 30, 2025	CITIGROUP INC	0.03%	57.11K	151.35K	-22.94K	-28.66%
Sep 30, 2025	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0.03%	57.62K	152.69K	19.63K	+51.67%
Sep 30, 2025	PINNACLE ASSOCIATES LTD	0.03%	61.11K	161.93K	0	0
Sep 30, 2025	FMR LLC	0.03%	63.32K	167.81K	3.29K	+5.48%
Sep 30, 2025	WINTON GROUP LTD	0.04%	70.9K	187.87K	70.9K	+100.00%
Sep 30, 2025	SEI INVESTMENTS CO	0.04%	77.75K	206.04K	77.75K	+100.00%
Sep 30, 2025	ADVENT CAPITAL MANAGEMENT /DE/	0.04%	80K	212M	80K	+100.00%
Sep 30, 2025	WOLVERINE ASSET MANAGEMENT LLC	0.05%	88.91K	235.6K	0	0
Sep 30, 2025	TOCQUEVILLE ASSET MANAGEMENT L.P.	0.05%	91K	241.15K	27.5K	+43.31%
Sep 30, 2025	HEADLANDS TECHNOLOGIES LLC	0.05%	96.26K	255.08K	96.26K	+100.00%
Sep 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.05%	99.49K	263.65K	-23.55K	-19.14%
Sep 30, 2025	SG AMERICAS SECURITIES, LLC	0.05%	103.71K	275K	80.04K	+338.14%
Sep 30, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.05%	106.48K	282.16K	-16.03K	-13.08%
Sep 30, 2025	PARALLEL ADVISORS, LLC	0.06%	117.42K	311.17K	-10K	-7.85%
Sep 30, 2025	DEUTSCHE BANK AG\	0.06%	118.42K	313.81K	21.16K	+21.76%
Sep 30, 2025	HIGHTOWER ADVISORS, LLC	0.06%	120.01K	318.03K	1.67K	+1.41%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0.07%	145.85K	386.51K	22.41K	+18.15%
Sep 30, 2025	ALLIANCEBERNSTEIN L.P.	0.11%	211.76K	561.16K	-68K	-24.31%
Sep 30, 2025	WOODLINE PARTNERS LP	0.19%	382.09K	1.01M	-1.12M	-74.59%
Sep 30, 2025	VICTORY CAPITAL MANAGEMENT INC	0.22%	426.87K	1.13M	403.66K	+1,739.78%
Sep 30, 2025	LOGOS GLOBAL MANAGEMENT LP	0.38%	750K	1.99M	750K	+100.00%
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.39%	773.9K	2.05M	481.5K	+164.67%
Sep 30, 2025	JPMORGAN CHASE & CO	0.48%	945.49K	2.51M	384.1K	+68.42%
Sep 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.13%	256.2K	678.93K	212.3K	+483.60%
Sep 30, 2025	TWO SIGMA ADVISERS, LP	0.97%	1.91M	5.06M	-185.7K	-8.87%
Sep 30, 2025	JANE STREET GROUP, LLC	0.99%	1.95M	5.18M	1.35M	+223.47%
Sep 30, 2025	TWO SIGMA INVESTMENTS, LP	1.14%	2.24M	5.93M	410.62K	+22.46%
Sep 30, 2025	MORGAN STANLEY	2.06%	4.06M	10.75M	3M	+284.24%
Sep 30, 2025	STATE STREET CORP	2.28%	4.48M	11.87M	720.11K	+19.16%
Sep 30, 2025	PENDERFUND CAPITAL MANAGEMENT LTD.	3.39%	6.68M	17.69M	0	0
Sep 30, 2025	WASATCH ADVISORS LP	3.59%	7.06M	18.71M	-3.28M	-31.71%
Sep 30, 2025	WALLEYE CAPITAL LLC	0.16%	319.19K	845.86K	319.19K	+100.00%
Sep 30, 2025	SUMMIT WEALTH GROUP, LLC	0.16%	323K	855.95K	0	0
Sep 30, 2025	BARCLAYS PLC	0.17%	335.61K	889.36K	-26.1K	-7.22%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.18%	357.36K	947K	334.79K	+1,483.40%
Sep 30, 2025	CITADEL ADVISORS LLC	0.21%	422.9K	1.12M	48.1K	+12.83%
Sep 30, 2025	INVESCO LTD.	0.31%	619.77K	1.64M	125.84K	+25.48%
Sep 30, 2025	GROUP ONE TRADING, L.P.	0.08%	162.59K	430.86K	-65.54K	-28.73%
Sep 30, 2025	UMB BANK, N.A.	0.09%	170K	450.5K	0	0
Sep 30, 2025	QUANTBOT TECHNOLOGIES LP	0.09%	179.64K	476.04K	179.64K	+100.00%
Jun 30, 2025	J.W. COLE ADVISORS, INC.	0.02%	43.9K	43.22K	0	0
Jun 30, 2025	CAPITAL ADVISORS WEALTH MANAGEMENT, LLC	0.02%	42.56K	41.89K	0	0
Jun 30, 2025	CFS INVESTMENT ADVISORY SERVICES, LLC	0.01%	24.55K	24K	0	0
Jun 30, 2025	MML INVESTORS SERVICES, LLC	0.01%	22.75K	22K	5.6K	+32.62%
Jun 30, 2025	PENTWATER CAPITAL MANAGEMENT LP	0.09%	181.29K	178.46K	0	0
Jun 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.01%	22.57K	22.22M	-249.04K	-91.69%
Jun 30, 2025	SIMPLEX TRADING, LLC	0.12%	230.46K	226K	83.72K	+57.05%
Jun 30, 2025	SQUAREPOINT OPS LLC	0.11%	214.39K	211.04K	-663.02K	-75.57%
Jun 30, 2025	UMB BANK, N.A.	0.09%	170K	167.35K	170K	+100.00%
Jun 30, 2025	PARALLEL ADVISORS, LLC	0.06%	127.42K	125.44K	117.42K	+1,174.24%
Jun 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.06%	123.04K	121.12K	28.7K	+30.42%
Jun 30, 2025	RAYMOND JAMES FINANCIAL INC	0.02%	41.06K	40.42K	0	0
Jun 30, 2025	PRIVATE ADVISOR GROUP, LLC	0.02%	40.11K	39.48K	0	0
Jun 30, 2025	PSI ADVISORS, LLC	0.02%	38.17K	37.58K	24.67K	+182.76%
Jun 30, 2025	SIVIA CAPITAL PARTNERS, LLC	0.01%	25.74K	25.34K	25.74K	+100.00%
Jun 30, 2025	WOLVERINE TRADING, LLC	0.01%	25.2K	25.04K	300	+1.20%
Jun 30, 2025	DIAMETRIC CAPITAL, LP	0.34%	678.82K	668.23K	248.65K	+57.80%
Jun 30, 2025	INVESCO LTD.	0.25%	493.93K	486.22K	238.45K	+93.33%
Jun 30, 2025	NJ STATE EMPLOYEES DEFERRED COMPENSATION PLAN	0.1%	195.13K	192.08K	0	0
Jun 30, 2025	GROUP ONE TRADING, L.P.	0.12%	228.13K	224.57K	78.4K	+52.37%
Jun 30, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.13%	249.5K	245.51K	249.5K	+100.00%
Jun 30, 2025	HIGHBRIDGE CAPITAL MANAGEMENT LLC	0.13%	254.27K	250.3K	0	0
Jun 30, 2025	PRELUDE CAPITAL MANAGEMENT, LLC	0.13%	265.59K	261.45K	97.28K	+57.80%
Jun 30, 2025	RHUMBLINE ADVISERS	0.14%	275.69K	271.27K	39.66K	+16.80%
Jun 30, 2025	NUVEEN, LLC	0.21%	422.61K	416.02K	-2.67M	-86.31%
Jun 30, 2025	BANK OF NEW YORK MELLON CORP	0.22%	427.06K	420.4K	11.92K	+2.87%
Jun 30, 2025	MILLENNIUM MANAGEMENT LLC	0.23%	452.65K	445.59K	-508.39K	-52.90%
Jun 30, 2025	JPMORGAN CHASE & CO	0.29%	561.4K	552.64K	-1.36M	-70.79%
Jun 30, 2025	JANE STREET GROUP, LLC	0.31%	603.78K	594.36K	423.55K	+235.01%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.31%	617.14K	607.51K	62.92K	+11.35%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0.42%	836.34K	822.96K	-690.92K	-45.24%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.12%	229K	224.42K	-53.1K	-18.82%
Jun 30, 2025	UBS GROUP AG	0.78%	1.54M	1.51M	867.29K	+129.46%
Jun 30, 2025	BLACKROCK, INC.	7.47%	14.71M	14.48M	220.05K	+1.52%
Jun 30, 2025	ROYAL BANK OF CANADA	0.59%	1.17M	1.15M	1.16M	+17,375.97%
Jun 30, 2025	WOODLINE PARTNERS LP	0.76%	1.5M	1.48M	0	0
Jun 30, 2025	NORTHERN TRUST CORP	0.91%	1.78M	1.76M	245.12K	+15.93%
Jun 30, 2025	TWO SIGMA INVESTMENTS, LP	0.93%	1.83M	1.8M	-903.29K	-33.07%
Jun 30, 2025	AQR CAPITAL MANAGEMENT LLC	0.09%	184.37K	181.49M	122.48K	+197.91%
Jun 30, 2025	CIBC WORLD MARKETS CORP	0.01%	24.6K	24.22K	-17.32K	-41.32%
Jun 30, 2025	ALLIANCEBERNSTEIN L.P.	0.14%	279.76K	275.4M	120.5K	+75.66%
Jun 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.15%	292.4K	287.84K	292.4K	+100.00%
Jun 30, 2025	SUMMIT WEALTH GROUP, LLC	0.16%	323K	318K	30K	+10.24%
Jun 30, 2025	BARCLAYS PLC	0.18%	361.71K	356K	125.58K	+53.18%
Jun 30, 2025	CITADEL ADVISORS LLC	0.19%	374.8K	368.95M	-21.6K	-5.45%
Jun 30, 2025	PRINCIPAL FINANCIAL GROUP INC	0.2%	393.29K	387.16K	380.03K	+2,866.88%
Jun 30, 2025		0.21%	422.61K	416.02K	-2.67M	-86.31%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.41%	798.75K	786.29M	-728.53K	-47.70%
Jun 30, 2025	MORGAN STANLEY	0.54%	1.06M	1.04B	-5.53M	-83.98%
Jun 30, 2025	TWO SIGMA ADVISERS, LP	1.06%	2.09M	2.06M	-433.3K	-17.15%
Jun 30, 2025	INDABA CAPITAL MANAGEMENT, L.P.	1.52%	3M	2.95M	0	0
Jun 30, 2025	STATE STREET CORP	1.91%	3.76M	3.7M	-789.53K	-17.36%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.33%	4.58M	4.51M	137.69K	+3.10%
Jun 30, 2025	PENDERFUND CAPITAL MANAGEMENT LTD.	3.39%	6.68M	6.57M	4.68M	+233.83%
Jun 30, 2025	TWO SEAS CAPITAL LP	5.06%	9.95M	9.8M	3.02M	+43.63%
Jun 30, 2025	WASATCH ADVISORS LP	5.25%	10.34M	10.18M	-591K	-5.41%
Jun 30, 2025	VANGUARD GROUP INC	5.95%	11.72M	11.53M	229.1K	+1.99%
Jun 30, 2025	MIRAE ASSET GLOBAL ETFS HOLDINGS LTD.	0.05%	107.55K	105.87K	-4.8K	-4.27%
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	0.07%	134.51K	132K	8.96K	+7.14%
Jun 30, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.06%	122.5K	120.59K	47.72K	+63.80%
Jun 30, 2025	WELLS FARGO & COMPANY/MN	0.06%	123.45K	121.52K	-1.09M	-89.86%
Jun 30, 2025	HIGHTOWER ADVISORS, LLC	0.06%	118.34K	116.49K	-6.55K	-5.24%
Jun 30, 2025	STATE OF WYOMING	0.06%	122.53K	120.62K	32.6K	+36.24%
Jun 30, 2025	NORTH STAR INVESTMENT MANAGEMENT CORP.	0.01%	25K	24.61K	25K	+100.00%
Jun 30, 2025	DAVIDSON KEMPNER CAPITAL MANAGEMENT LP	0.11%	222.48K	219.01K	0	0
Jun 30, 2025	SJS INVESTMENT CONSULTING INC.	0.01%	25K	24.61K	0	0
Jun 30, 2025	MARSHALL WACE, LLP	2.7%	5.31M	5.21M	1.68M	+46.22%
Jun 30, 2025	BREVAN HOWARD CAPITAL MANAGEMENT LP	0.04%	78.72K	77.14K	45.78K	+139.02%
Jun 30, 2025	VIRTU FINANCIAL LLC	0.04%	76.62K	75K	40.71K	+113.38%
Jun 30, 2025	SUMMIT FINANCIAL, LLC	0.04%	74.79K	74.31K	9.59K	+14.71%
Jun 30, 2025	TOCQUEVILLE ASSET MANAGEMENT L.P.	0.03%	63.5K	62.51K	-1.5K	-2.31%
Jun 30, 2025	PINNACLE ASSOCIATES LTD	0.03%	61.11K	60.15K	-320	-0.52%
Jun 30, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.25%	485.6K	478.03K	342.07K	+238.31%
Jun 30, 2025	FMR LLC	0.03%	60.03K	59.1M	-13.14K	-17.96%
Jun 30, 2025	FOUNDATIONS INVESTMENT ADVISORS, LLC	0.03%	50.16K	49.38K	-15	-0.03%
Jun 30, 2025	LOS ANGELES CAPITAL MANAGEMENT LLC	0.02%	48.17K	47.42K	0	0
Jun 30, 2025	CONGRESS WEALTH MANAGEMENT LLC / DE /	0.02%	46.3K	45.58K	0	0
Jun 30, 2025	QUADRATURE CAPITAL LTD	0.02%	46.27K	45.63K	-4.16K	-8.25%
Jun 30, 2025	BOOMFISH WEALTH GROUP, LLC	0.02%	45.31K	44.6K	10.31K	+29.46%
Mar 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.14%	271.61K	391.12K	118.4K	+77.28%
Mar 31, 2025	TWO SIGMA ADVISERS, LP	1.29%	2.53M	3.64M	-1.09M	-30.12%
Mar 31, 2025	WELLS FARGO & COMPANY/MN	0.62%	1.22M	1.75M	1.11M	+1,023.18%
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	0.49%	961.04K	1.38M	131.15K	+15.80%
Mar 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.39%	761.98K	1.1M	201.7K	+36.00%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.28%	554.22K	798.07K	0	0
Mar 31, 2025	BARCLAYS PLC	0.12%	236.13K	340K	-123.1K	-34.27%
Mar 31, 2025	BANK OF NEW YORK MELLON CORP	0.21%	415.14K	597.8K	-12.39K	-2.90%
Mar 31, 2025	CITADEL ADVISORS LLC	0.2%	396.4K	570.82K	-219.9K	-35.68%
Mar 31, 2025	SUMMIT WEALTH GROUP, LLC	0.15%	293K	422K	136K	+86.62%
Mar 31, 2025	DIAMETRIC CAPITAL, LP	0.22%	430.18K	619.45K	76.17K	+21.52%
Mar 31, 2025	RHUMBLINE ADVISERS	0.12%	236.03K	339.87K	-10.88K	-4.41%
Mar 31, 2025	DAVIDSON KEMPNER CAPITAL MANAGEMENT LP	0.11%	222.48K	320.37K	0	0
Mar 31, 2025	NJ STATE EMPLOYEES DEFERRED COMPENSATION PLAN	0.1%	195.13K	280.98K	0	0
Mar 31, 2025	CITIGROUP INC	0.1%	186.65K	268.77K	-5.48K	-2.85%
Mar 31, 2025	ALLIANCEBERNSTEIN L.P.	0.08%	159.26K	229.33K	0	0
Mar 31, 2025	PENDERFUND CAPITAL MANAGEMENT LTD.	1.02%	2M	10.79M	2M	+100.00%
Mar 31, 2025	JPMORGAN CHASE & CO	0.98%	1.92M	2.77M	-532.51K	-21.70%
Mar 31, 2025	SQUAREPOINT OPS LLC	0.45%	877.41K	1.26M	538.38K	+158.80%
Mar 31, 2025	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.42%	822.62K	1.18M	-109.39K	-11.74%
Mar 31, 2025	MORGAN STANLEY	3.36%	6.59M	9.48M	277.26K	+4.39%
Mar 31, 2025	STATE STREET CORP	2.32%	4.55M	6.55M	44.01K	+0.98%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.27%	4.45M	6.4M	106.35K	+2.45%
Mar 31, 2025	MARSHALL WACE, LLP	1.85%	3.63M	5.23M	3.63M	+100.00%
Mar 31, 2025		1.57%	3.09M	4.45M	3.09M	+100.00%
Mar 31, 2025	INDABA CAPITAL MANAGEMENT, L.P.	1.53%	3M	4.32M	0	0
Mar 31, 2025	RHENMAN & PARTNERS ASSET MANAGEMENT AB	0.54%	1.07M	1.54M	-848.51K	-44.31%
Mar 31, 2025	HRT FINANCIAL LP	0.34%	669.83K	964K	109.28K	+19.50%
Mar 31, 2025	NORTHERN TRUST CORP	0.78%	1.54M	2.22M	-1.08K	-0.07%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.78%	1.53M	2.2M	-1.23M	-44.53%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0.78%	1.53M	2.2M	-102.72K	-6.30%
Mar 31, 2025	WOODLINE PARTNERS LP	0.77%	1.5M	2.17M	8	0.00%
Mar 31, 2025	UBS GROUP AG	0.34%	669.92K	964.68K	-207.02K	-23.61%
Mar 31, 2025	D. E. SHAW & CO., INC.	0.14%	275.71K	397.02K	24.12K	+9.59%
Mar 31, 2025	BLACKROCK, INC.	7.39%	14.49M	20.87M	257.6K	+1.81%
Mar 31, 2025	VANGUARD GROUP INC	5.86%	11.49M	16.54M	-228.02K	-1.95%
Mar 31, 2025	WASATCH ADVISORS LP	5.57%	10.93M	15.74M	-13.55M	-55.35%
Mar 31, 2025	BELLEVUE GROUP AG	4.94%	9.69M	13.96M	-250K	-2.51%
Mar 31, 2025	TWO SEAS CAPITAL LP	3.53%	6.93M	9.98M	700K	+11.23%
Mar 31, 2025	TWO SIGMA INVESTMENTS, LP	1.39%	2.73M	3.93M	-809.07K	-22.85%
Mar 31, 2025	GRAHAM CAPITAL MANAGEMENT, L.P.	0.25%	487.74K	702.34K	295.32K	+153.48%
Mar 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.14%	282.1K	406.22K	-201.6K	-41.68%
Mar 31, 2025	INVESCO LTD.	0.13%	255.48K	367.89K	157.65K	+161.14%
Mar 31, 2025	HIGHBRIDGE CAPITAL MANAGEMENT LLC	0.13%	254.27K	366.14K	0	0
Mar 31, 2025	PENTWATER CAPITAL MANAGEMENT LP	0.09%	181.29K	261.06K	0	0
Mar 31, 2025	JANE STREET GROUP, LLC	0.09%	180.23K	259.53K	59.64K	+49.46%
Mar 31, 2025	PRELUDE CAPITAL MANAGEMENT, LLC	0.09%	168.31K	242.36K	48.63K	+40.64%
Mar 31, 2025	GROUP ONE TRADING, L.P.	0.08%	149.72K	215.6K	52.59K	+54.14%
Mar 31, 2024	WELLINGTON MANAGEMENT GROUP LLP	0.32%	360.83K	967.02K	360.83K	+100.00%
Mar 31, 2024	JACOBS LEVY EQUITY MANAGEMENT, INC	0.63%	704.1K	1.89M	-353.79K	-33.44%
Mar 31, 2024	SCHONFELD STRATEGIC ADVISORS LLC	0.84%	947.51K	2.54M	-143.82K	-13.18%
Mar 31, 2024	JANE STREET GROUP, LLC	0.87%	983.34K	2.64M	707.7K	+256.74%
Mar 31, 2024	PARKMAN HEALTHCARE PARTNERS LLC	1.02%	1.14M	3.06M	-282.31K	-19.81%
Mar 31, 2024	PLATINUM INVESTMENT MANAGEMENT LTD	1.42%	1.6M	4.28M	-1.21M	-43.16%
Mar 31, 2024	QUBE RESEARCH & TECHNOLOGIES LTD	1.43%	1.61M	4.31M	1.17M	+269.29%
Mar 31, 2024	MORGAN STANLEY	1.46%	1.64M	4.4M	537.36K	+48.63%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	1.56%	1.75M	4.7M	640.95K	+57.63%
Mar 31, 2024	JPMORGAN CHASE & CO	1.86%	2.09M	5.59M	222.63K	+11.95%
Mar 31, 2024	RENAISSANCE TECHNOLOGIES LLC	1.88%	2.12M	5.67M	696.4K	+49.04%
Mar 31, 2024	MARSHALL WACE, LLP	1.97%	2.22M	5.94M	1.76M	+384.09%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	2.99%	3.36M	9.02M	2.31M	+218.16%
Mar 31, 2024	GREAT POINT PARTNERS LLC	7.12%	8M	21.44M	8M	+100.00%
Mar 31, 2024	PRINCIPAL FINANCIAL GROUP INC	0.03%	29.15K	78.13K	-4.48K	-13.33%
Mar 31, 2024	BOOMFISH WEALTH GROUP, LLC	0.03%	29.9K	80.12K	29.9K	+100.00%
Mar 31, 2024	PRUDENTIAL FINANCIAL INC	0.03%	32.06K	85.92K	-1.2K	-3.61%
Mar 31, 2024	OMERS ADMINISTRATION CORP	0.03%	32.2K	86.3K	32.2K	+100.00%
Mar 31, 2024	EATON FINANCIAL HOLDINGS COMPANY, LLC	0.03%	34.03K	91.2K	0	0
Mar 31, 2024	CTC ALTERNATIVE STRATEGIES, LTD.	0.03%	37.1K	99.43K	37.1K	+100.00%
Mar 31, 2024	DAIWA SECURITIES GROUP INC.	0.03%	38.5K	103K	0	0
Mar 31, 2024	JUMP FINANCIAL, LLC	0.03%	38.76K	103.88K	12.94K	+50.11%
Mar 31, 2024	TOCQUEVILLE ASSET MANAGEMENT L.P.	0.04%	39.75K	106.53K	39.75K	+100.00%
Mar 31, 2024	VERITION FUND MANAGEMENT LLC	0.04%	41K	109.88K	41K	+100.00%
Mar 31, 2024	XTX TOPCO LTD	0.04%	42.82K	114.76K	42.82K	+100.00%
Mar 31, 2024	BELPOINTE ASSET MANAGEMENT LLC	0.04%	47K	125.96K	47K	+100.00%
Mar 31, 2024	BANK OF MONTREAL /CAN/	0.05%	50.9K	138.96K	50.9K	+100.00%
Mar 31, 2024	RAYMOND JAMES & ASSOCIATES	0.05%	56.88K	152.43K	17.53K	+44.54%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.05%	57.99K	155.42K	0	0
Mar 31, 2024	JEFFERIES FINANCIAL GROUP INC.	0.03%	38.7K	103.72K	38.7K	+100.00%
Mar 31, 2024	ADVISOR GROUP HOLDINGS, INC.	0.07%	78.63K	210.73K	6.54K	+9.07%
Mar 31, 2024	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.07%	83.4K	224K	83.4K	+100.00%
Mar 31, 2024	RUSSELL INVESTMENTS GROUP, LTD.	0.08%	84.37K	226.1K	-329	-0.39%
Mar 31, 2024	WOLVERINE ASSET MANAGEMENT LLC	0.08%	87.38K	234.19K	0	0
Mar 31, 2024	SUSQUEHANNA PORTFOLIO STRATEGIES, LLC	0.08%	92.3K	247.36K	92.3K	+100.00%
Mar 31, 2024	STONERIDGE INVESTMENT PARTNERS LLC	0.08%	93.4K	250K	64.15K	+219.25%
Mar 31, 2024	FMR LLC	0.09%	105.17K	281.86K	-171.68K	-62.01%
Mar 31, 2024	GROUP ONE TRADING, L.P.	0.11%	120.76K	323.63K	120.76K	+100.00%
Mar 31, 2024	BALYASNY ASSET MANAGEMENT L.P.	0.14%	159.04K	426.22K	121.85K	+327.66%
Mar 31, 2024	SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC	0.15%	166.46K	446.11K	166.46K	+100.00%
Mar 31, 2024	MARATHON TRADING INVESTMENT MANAGEMENT LLC	0.15%	170.5K	456.94K	149.5K	+711.90%
Mar 31, 2024	HIGHTOWER ADVISORS, LLC	0.17%	187.17K	496K	137.6K	+277.59%
Mar 31, 2024	VANGUARD GROUP INC	7.85%	8.83M	23.66M	3.69M	+71.80%
Mar 31, 2024	WASATCH ADVISORS LP	8.12%	9.13M	24.47M	238.54K	+2.68%
Mar 31, 2024	ORBIMED ADVISORS LLC	12.2%	13.71M	36.74M	13.71M	+100.00%
Mar 31, 2024	CUBIST SYSTEMATIC STRATEGIES, LLC	0.24%	273.29K	732.42K	88.32K	+47.75%
Mar 31, 2024	SQUAREPOINT OPS LLC	0.27%	300.3K	804.8K	212.59K	+242.37%
Mar 31, 2024	NORTHERN TRUST CORP	0.27%	308.68K	827.25K	72.08K	+30.47%
Mar 31, 2024	HRT FINANCIAL LP	0.39%	442.03K	1.18M	394.06K	+821.45%
Mar 31, 2024	GSA CAPITAL PARTNERS LLP	0.4%	449.13K	1.2M	-679.02K	-60.19%
Mar 31, 2024	STATE STREET CORP	0.49%	551.25K	1.48M	167.5K	+43.65%
Mar 31, 2024	WALLEYE TRADING LLC	0.51%	575K	1.54M	-478.7K	-45.43%
Mar 31, 2024	TWO SIGMA ADVISERS, LP	3.18%	3.57M	9.57M	1.42M	+66.30%
Mar 31, 2024	MILLENNIUM MANAGEMENT LLC	5.05%	5.68M	15.23M	2.23M	+64.71%
Mar 31, 2024	WOODLINE PARTNERS LP	7.05%	7.92M	21.23M	7.63M	+2,628.21%
Mar 31, 2024	BELLEVUE GROUP AG	8.85%	9.94M	26.65M	5.74M	+136.52%
Mar 31, 2024	MAN GROUP PLC	0.39%	440.77K	1.18M	223.79K	+103.13%
Mar 31, 2024	BLACKROCK INC.	2.53%	2.84M	7.61M	725.92K	+34.36%
Mar 31, 2024	MEDITOR GROUP LTD	3.37%	3.79M	10.16M	0	0
Mar 31, 2024	TWO SIGMA INVESTMENTS, LP	3.54%	3.98M	10.65M	1.64M	+70.30%
Mar 31, 2024	TWO SEAS CAPITAL LP	3.71%	4.17M	11.16M	-3.52M	-45.80%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	4.04%	4.55M	12.18M	4.37M	+2,474.69%
Mar 31, 2024	D. E. SHAW & CO., INC.	4.58%	5.14M	13.78M	3.93M	+323.96%
Mar 31, 2024	NJ STATE EMPLOYEES DEFERRED COMPENSATION PLAN	0.17%	195.13K	522.94K	0	0
Mar 31, 2024	POINT72 ASSET MANAGEMENT, L.P.	0.18%	200K	536K	200K	+100.00%
Mar 31, 2024	CITIGROUP INC	0.18%	200K	536K	197.3K	+7,307.41%
Mar 31, 2024	DAVIDSON KEMPNER CAPITAL MANAGEMENT LP	0.2%	222.48K	594.03K	0	0
Mar 31, 2024	HAP TRADING, LLC	0.2%	225K	309.38K	100K	+80.00%
Mar 31, 2024	CAPTION MANAGEMENT, LLC	0.2%	225K	603K	0	0
Mar 31, 2024	WALLEYE CAPITAL LLC	0.2%	227.63K	610.05K	13.63K	+6.37%
Mar 31, 2024	CITADEL ADVISORS LLC	0.21%	238K	637.84K	98.8K	+70.98%
Mar 31, 2024	PARALLEL ADVISORS, LLC	0.21%	239K	640.52K	-239K	-50.00%
Mar 31, 2024	PINNACLE ASSOCIATES LTD	0.25%	285.2K	764.35K	1.95K	+0.69%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.36%	409.1K	1.1M	105.2K	+34.62%
Dec 31, 2023	CITADEL ADVISORS LLC	0.41%	462.28K	1.38M	-189.27K	-29.05%
Dec 31, 2023	PARALLEL ADVISORS, LLC	0.43%	478K	1.43M	0	0
Dec 31, 2023	WHITEFORT CAPITAL MANAGEMENT, LP	0.79%	885.52K	2.65M	885.52K	+100.00%
Dec 31, 2023	WALLEYE TRADING LLC	0.94%	1.05M	3.15M	949.6K	+912.20%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.95%	1.06M	3.16M	-119.6K	-10.16%
Dec 31, 2023	JACOBS LEVY EQUITY MANAGEMENT, INC	0.95%	1.06M	3.16M	-1.21M	-53.28%
Dec 31, 2023	MEDITOR GROUP LTD	3.39%	3.79M	11.34M	0	0
Dec 31, 2023	STATE STREET CORP	0.34%	383.75K	1.15M	81.3K	+26.88%
Dec 31, 2023	MARINER INVESTMENT GROUP LLC	0.36%	400K	510K	400K	+100.00%
Dec 31, 2023	BELLEVUE GROUP AG	3.76%	4.2M	12.57M	0	0
Dec 31, 2023	VANGUARD GROUP INC	4.59%	5.14M	15.36M	396.39K	+8.36%
Dec 31, 2023	TWO SEAS CAPITAL LP	6.87%	7.69M	22.98M	13.95K	+0.18%
Dec 31, 2023	WASATCH ADVISORS LP	7.95%	8.89M	26.58M	-2.63M	-22.86%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.16%	176.54K	527.84K	72.03K	+68.93%
Dec 31, 2023	CUBIST SYSTEMATIC STRATEGIES, LLC	0.17%	184.97K	553.06K	72.17K	+63.98%
Dec 31, 2023	NJ STATE EMPLOYEES DEFERRED COMPENSATION PLAN	0.17%	195.13K	583.42K	0	0
Dec 31, 2023	WALLEYE CAPITAL LLC	0.19%	214K	639.86K	214K	+100.00%
Dec 31, 2023	UBS GROUP AG	0.19%	215K	642.85K	215K	+100.00%
Dec 31, 2023	MAN GROUP PLC	0.19%	216.99K	648.79K	167.56K	+339.03%
Dec 31, 2023	HIGHBRIDGE CAPITAL MANAGEMENT LLC	0.2%	221.72K	662.95M	-32.54K	-12.80%
Dec 31, 2023	DAVIDSON KEMPNER CAPITAL MANAGEMENT LP	0.2%	222.48K	663K	0	0
Dec 31, 2023	QUBE RESEARCH & TECHNOLOGIES LTD	0.39%	435.24K	1.3M	403.68K	+1,279.00%
Dec 31, 2023	MARSHALL WACE, LLP	0.41%	457.76K	1.37M	-1.12M	-70.92%
Dec 31, 2023	CAPTION MANAGEMENT, LLC	0.2%	225K	672.75K	-148.8K	-39.81%
Dec 31, 2023	NORTHERN TRUST CORP	0.21%	236.59K	707.41K	7.88K	+3.45%
Dec 31, 2023	MONACO ASSET MANAGEMENT SAM	0.22%	243.64K	728.49K	-928.14K	-79.21%
Dec 31, 2023	JANE STREET GROUP, LLC	0.25%	275.65K	824.19K	7.16K	+2.67%
Dec 31, 2023	FMR LLC	0.25%	276.85K	827.77K	23.79K	+9.40%
Dec 31, 2023	PINNACLE ASSOCIATES LTD	0.25%	283.26K	846.93K	-5.87K	-2.03%
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	0.17%	194.5K	581.56K	-5.5K	-2.75%
Dec 31, 2023	WOODLINE PARTNERS LP	0.26%	290.38K	868.24K	290.38K	+100.00%
Dec 31, 2023	IKARIAN CAPITAL, LLC	0.3%	337.64K	1.01M	-1.4M	-80.57%
Dec 31, 2023	UBS OCONNOR LLC	0.47%	527.12K	1.58M	-104.82K	-16.59%
Dec 31, 2023	SCHONFELD STRATEGIC ADVISORS LLC	0.98%	1.09M	3.26M	-140.5K	-11.41%
Dec 31, 2023	MORGAN STANLEY	0.99%	1.11M	3.3M	-998.78K	-47.48%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	0.99%	1.11M	3.33M	142.01K	+14.64%
Dec 31, 2023	GSA CAPITAL PARTNERS LLP	1.01%	1.13M	3.37M	11.49K	+1.03%
Dec 31, 2023	D. E. SHAW & CO., INC.	1.08%	1.21M	3.63M	1.21M	+100.00%
Dec 31, 2023	RENAISSANCE TECHNOLOGIES LLC	1.27%	1.42M	4.25M	1.21M	+588.85%
Dec 31, 2023	PARKMAN HEALTHCARE PARTNERS LLC	1.27%	1.43M	4.26M	-571.87K	-28.64%
Dec 31, 2023	TANG CAPITAL MANAGEMENT LLC	1.65%	1.85M	5.53M	0	0
Dec 31, 2023	JPMORGAN CHASE & CO	1.66%	1.86M	5.57M	-1.86K	-0.10%
Dec 31, 2023	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.31%	352.05K	1.05M	-61.65K	-14.90%
Dec 31, 2023	CITIGROUP INC	0.34%	377.99K	1.13M	363.06K	+2,431.25%
Dec 31, 2023	BLACKROCK INC.	1.89%	2.11M	6.32M	145.02K	+7.37%
Dec 31, 2023	TWO SIGMA ADVISERS, LP	1.92%	2.15M	6.42M	610.3K	+39.73%
Dec 31, 2023	TWO SIGMA INVESTMENTS, LP	2.09%	2.33M	6.98M	876.48K	+60.12%
Dec 31, 2023	PLATINUM INVESTMENT MANAGEMENT LTD	2.51%	2.81M	8.4M	-378.96K	-11.88%
Dec 31, 2023	ARMISTICE CAPITAL, LLC	2.86%	3.2M	9.57M	3.2M	+100.00%

Insiders

Among the ESPR insiders holding of 0.56% of the stake in company, BIOTECH TARGET N V, 10 percent owner, holds the largest shares of 4.48M. JANNEY DANIEL, director, is the second largest ESPR insider with ownership of 1.48M shares. KOENIG SHELDON L., President and CEO, stands third with possession of 1.47M shares of that stake.

Insiders	Designation	Shares Held
BIOTECH TARGET N V	10 percent owner	4.48M
JANNEY DANIEL	director	1.48M
KOENIG SHELDON L.	President and CEO	1.47M
BOXER CAPITAL, LLC	10 percent owner	1.1M
NEWTON ROGER S	director	548.73K
HALLADAY BENJAMIN	Chief Financial Officer	467.53K
LOOKER BENJAMIN	General Counsel	385.91K
WARREN ERIC	Chief Commercial Officer	370.22K
FOODY JOANNE M.	Chief Medical Officer	272.86K
MAYLEBEN TIMOTHY M	President & CEO	112K
CARROLL J MARTIN	director	36.5K
BARTRAM RICHARD	Chief Financial Officer	11.09K
ROCAMBOLI STEPHEN	director	8.11K
VITULLO NICOLE	director	0

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Dec 17, 2025	KOENIG SHELDON L.	SALE	3.67	48.24K	177.2K	1.47M
Dec 17, 2025	HALLADAY BENJAMIN	SALE	3.67	7.34K	26.9K	467.53K
Dec 17, 2025	LOOKER BENJAMIN	SALE	3.67	6.52K	23.9K	385.91K
Sep 17, 2025	LOOKER BENJAMIN	SALE	2.80	6.27K	17.57K	393.67K
Sep 17, 2025	KOENIG SHELDON L.	SALE	2.79	28.43K	79.25K	1.52M
Sep 17, 2025	HALLADAY BENJAMIN	SALE	2.81	7.05K	19.79K	474.86K
Jul 17, 2025	LOOKER BENJAMIN	SALE	1.13	1.3K	1.47K	399.94K
Jul 17, 2025	HALLADAY BENJAMIN	SALE	1.11	11	12.27	474.46K
Jun 17, 2025	HALLADAY BENJAMIN	SALE	1.15	7.23K	8.33K	474.47K
Jun 17, 2025	KOENIG SHELDON L.	SALE	1.11	30.47K	33.8K	1.54M
Jun 17, 2025	LOOKER BENJAMIN	SALE	1.15	6.42K	7.4K	401.24K
Apr 17, 2025	WARREN ERIC	SALE	0.98	108	105.62	370.22K
Apr 17, 2025	HALLADAY BENJAMIN	SALE	0.96	8	7.71	481.7K
Mar 18, 2025	KOENIG SHELDON L.	SALE	1.50	13.05K	19.62K	1.57M
Mar 18, 2025	HALLADAY BENJAMIN	SALE	1.48	3.54K	5.24K	481.71K
Mar 18, 2025	WARREN ERIC	SALE	1.49	2.43K	3.62K	370.33K
Feb 19, 2025	HALLADAY BENJAMIN	SALE	1.86	11	20.46	240.67K
Feb 19, 2025	WARREN ERIC	SALE	1.87	239	446.45	159.76K
Jan 17, 2025	WARREN ERIC	SALE	2.26	123	277.98	160K
Jan 17, 2025	HALLADAY BENJAMIN	SALE	2.27	9	20.39	240.68K
Dec 17, 2024	KOENIG SHELDON L.	SALE	2.47	12.45K	30.69K	739.82K
Dec 17, 2024	WARREN ERIC	SALE	2.43	2.23K	5.43K	160.12K
Dec 17, 2024	HALLADAY BENJAMIN	SALE	2.42	3.25K	7.87K	240.69K
Nov 19, 2024	WARREN ERIC	SALE	2.17	197	426.51	162.36K
Oct 17, 2024	WARREN ERIC	SALE	2.12	107	226.73	162.55K
Sep 17, 2024	WARREN ERIC	SALE	1.78	2.61K	4.65K	162.66K
Sep 17, 2024	KOENIG SHELDON L.	SALE	1.80	14.55K	26.13K	752.27K
Aug 19, 2024	WARREN ERIC	SALE	1.95	211	410.61	165.27K
Jul 17, 2024	FOODY JOANNE M.	SALE	2.60	917	2.38K	272.86K
Jul 17, 2024	WARREN ERIC	SALE	2.59	108	279.4	165.48K
Jun 18, 2024	FOODY JOANNE M.	SALE	2.87	3.29K	9.42K	273.78K
Jun 18, 2024	WARREN ERIC	SALE	2.86	2.54K	7.25K	165.59K
May 17, 2024	WARREN ERIC	SALE	2.48	192	476.74	168.13K
Sep 20, 2023	WARREN ERIC	SALE	1.25	742	923.79	68.32K
Aug 18, 2023	WARREN ERIC	SALE	1.41	243	343.6	69.06K
Jul 19, 2023	WARREN ERIC	SALE	1.58	106	168.01	69.3K
Jun 21, 2023	WARREN ERIC	SALE	1.48	603	894.25	69.41K
May 17, 2023	WARREN ERIC	SALE	1.62	219	355.66	70.01K
May 11, 2023	CARROLL J MARTIN	PURCHASE	1.57	23.09K	36.29K	36.5K
May 10, 2023	CARROLL J MARTIN	PURCHASE	1.49	8.41K	12.55K	13.41K
May 10, 2023	ROCAMBOLI STEPHEN	PURCHASE	1.50	8.11K	12.13K	8.11K
May 09, 2023	KOENIG SHELDON L.	PURCHASE	1.26	20K	25.19K	312.82K
Apr 19, 2023	LOOKER BENJAMIN	SALE	1.27	1.29K	1.64K	83.66K
Apr 19, 2023	FOODY JOANNE M.	SALE	1.27	938	1.19K	127.06K
Apr 19, 2023	WARREN ERIC	SALE	1.28	115	146.97	70.23K
Mar 17, 2023	FOODY JOANNE M.	SALE	1.78	3.81K	6.79K	128K
Mar 17, 2023	WARREN ERIC	SALE	1.78	526	937.49	70.35K
Mar 17, 2023	KOENIG SHELDON L.	SALE	1.78	7K	12.48K	292.82K
Mar 07, 2023	WARREN ERIC	SALE	5.05	5.09K	25.73K	48.57K
Mar 07, 2023	FOODY JOANNE M.	SALE	5.07	3.88K	19.67K	103.06K
Mar 07, 2023	KOENIG SHELDON L.	SALE	5.06	5.44K	27.51K	194.82K
Jan 18, 2023	FOODY JOANNE M.	SALE	6.99	1.19K	8.32K	106.94K
Jan 18, 2023	LOOKER BENJAMIN	SALE	7.00	6.35K	44.4K	64.45K
Oct 18, 2022	WARREN ERIC	SALE	7.69	107	822.83	53.66K
Oct 18, 2022	FOODY JOANNE M.	SALE	7.69	942	7.24K	108.14K
Sep 19, 2022	KOENIG SHELDON L.	SALE	6.94	3.39K	23.55K	198.26K
Sep 19, 2022	WARREN ERIC	SALE	6.92	255	1.76K	53.77K
Aug 31, 2022	WARREN ERIC	PURCHASE	7.46	1K	7.46K	54.02K
Aug 17, 2022	WARREN ERIC	SALE	6.82	199	1.36K	53.02K
Aug 05, 2022	KOENIG SHELDON L.	PURCHASE	5.80	8.61K	49.95K	198.77K
Jul 19, 2022	WARREN ERIC	SALE	6.58	431	2.84K	53.22K
Jul 19, 2022	FOODY JOANNE M.	SALE	6.55	3.9K	25.55K	109.08K
Jun 17, 2022	KOENIG SHELDON L.	SALE	4.99	4.55K	22.72K	190.17K
Jun 17, 2022	WARREN ERIC	SALE	4.90	256	1.25K	53.65K
Jun 02, 2022	CARROLL J MARTIN	PURCHASE	5.64	5K	28.18K	5K
May 17, 2022	WARREN ERIC	SALE	5.98	196	1.17K	53.91K
Mar 17, 2022	KOENIG SHELDON L.	SALE	4.58	571	2.62K	194.72K
May 24, 2021	BIOTECH TARGET N V	PURCHASE	20.22	100K	2.02M	4.48M
May 19, 2021	BIOTECH TARGET N V	PURCHASE	20.37	200K	4.07M	4.38M
May 06, 2021	BIOTECH TARGET N V	PURCHASE	20.57	80K	1.65M	4.18M
May 05, 2021	BIOTECH TARGET N V	PURCHASE	20.02	150K	3M	4.1M
Nov 03, 2020	BIOTECH TARGET N V	PURCHASE	25.31	200K	5.06M	3.95M
Mar 11, 2020	MAYLEBEN TIMOTHY M	PURCHASE	43.00	2.5K	107.5K	112K
Feb 28, 2020	MAYLEBEN TIMOTHY M	PURCHASE	49.00	5K	245K	109.5K
Jan 23, 2020	BIOTECH TARGET N V	PURCHASE	52.12	20K	1.04M	3.75M
Nov 06, 2019	MAYLEBEN TIMOTHY M	PURCHASE	36.98	5K	184.9K	83.66K
Nov 06, 2019	BIOTECH TARGET N V	PURCHASE	37.30	75K	2.8M	3.73M
Sep 06, 2019	MAYLEBEN TIMOTHY M	PURCHASE	35.25	2.5K	88.13K	78.66K
Sep 04, 2019	MAYLEBEN TIMOTHY M	PURCHASE	34.22	4.85K	166.04K	76.02K
Sep 04, 2019	BIOTECH TARGET N V	PURCHASE	33.78	80K	2.7M	3.65M
Aug 01, 2019	MAYLEBEN TIMOTHY M	PURCHASE	39.56	5K	197.8K	71.16K
Jul 23, 2019	BIOTECH TARGET N V	PURCHASE	42.65	50K	2.13M	3.57M
Jun 28, 2019	MAYLEBEN TIMOTHY M	PURCHASE	46.00	5K	230K	66.16K
Apr 03, 2019	BARTRAM RICHARD	SALE	43.62	1.5K	65.43K	11.09K
Mar 29, 2019	MAYLEBEN TIMOTHY M	PURCHASE	40.00	5K	200K	61.16K
Mar 20, 2019	MAYLEBEN TIMOTHY M	PURCHASE	43.48	5K	217.4K	56.16K
Mar 19, 2019	VITULLO NICOLE	SALE	45.25	1.7K	76.93K	0
Mar 14, 2019	MAYLEBEN TIMOTHY M	PURCHASE	48.73	5K	243.65K	51.16K
Mar 14, 2019	BIOTECH TARGET N V	PURCHASE	49.89	50K	2.49M	3.52M
Mar 12, 2019	NEWTON ROGER S	SALE	50.06	25K	1.25M	548.73K
Jan 04, 2019	BIOTECH TARGET N V	PURCHASE	41.29	80K	3.3M	3.47M
Dec 24, 2018	BIOTECH TARGET N V	PURCHASE	39.91	50K	2M	3.39M
Dec 17, 2018	BIOTECH TARGET N V	PURCHASE	47.73	60K	2.86M	3.34M
Nov 05, 2018	BOXER CAPITAL, LLC	SALE	60.28	5K	301.4K	1.1M
Nov 02, 2018	BOXER CAPITAL, LLC	SALE	55.25	37.5K	2.07M	1.16M
Nov 02, 2018	NEWTON ROGER S	SALE	50.76	227	11.52K	573.73K
Nov 01, 2018	NEWTON ROGER S	SALE	50.01	2.6K	130.03K	573.95K
Oct 18, 2018	NEWTON ROGER S	SALE	50.00	100	5K	576.55K
Oct 17, 2018	NEWTON ROGER S	SALE	50.02	12.67K	633.9K	576.65K
Oct 16, 2018	NEWTON ROGER S	SALE	50.01	9.4K	470.09K	589.33K
Aug 27, 2018	NEWTON ROGER S	SALE	50.65	12.1K	612.87K	598.73K
Aug 17, 2018	NEWTON ROGER S	SALE	50.06	7.3K	365.44K	616.43K
Aug 03, 2018	BIOTECH TARGET N V	PURCHASE	46.14	50K	2.31M	3.28M
Jul 12, 2018	BIOTECH TARGET N V	PURCHASE	41.77	50K	2.09M	3.23M
Jun 29, 2018	BIOTECH TARGET N V	PURCHASE	39.48	50K	1.97M	3.18M
Jun 21, 2018	BIOTECH TARGET N V	PURCHASE	38.57	60K	2.31M	3.13M
Jun 07, 2018	BIOTECH TARGET N V	PURCHASE	37.79	60K	2.27M	3.07M
Jun 05, 2018	BIOTECH TARGET N V	PURCHASE	38.47	60K	2.31M	3.01M
May 21, 2018	BIOTECH TARGET N V	PURCHASE	38.77	80K	3.1M	2.95M
May 18, 2018	BIOTECH TARGET N V	PURCHASE	42.24	50K	2.11M	2.87M
Mar 29, 2018	NEWTON ROGER S	SALE	70.71	200	14.14K	623.73K
Jan 25, 2018	VITULLO NICOLE	SALE	71.79	11.67K	838.08K	15.33K
Dec 06, 2017	VITULLO NICOLE	SALE	53.85	9.33K	502.21K	25.93K
Mar 21, 2017	JANNEY DANIEL	SALE	45.43	111.31K	5.06M	1.48M

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES105.15K8

NET SHARES-105.15K8

SHARES HELD5.59M8

% NET SHARES-101.88%0%

Frequently Asked Questions