How many institutions own ELVN stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own ELVN shares is 184, representing 102.25% of the company's common stock.

Who are the major shareholders selling Enliven Therapeutics, Inc. stock?

NUVEEN, LLC, in the last quarter, reduced its stake in ELVN by -2.58% restricting it's holding to 105.45 thousand shares of worth nearly $1.62M. HIGHVISTA STRATEGIES LLC also lessened -68.15% of the ELVN shares from its portfolio, reducing its holding to 82.54 thousand shares of worth $1.27M. NORTHERN TRUST CORP also shunned ELVN shares holding by -10.7% last quarter which brought its holding to 352.24 thousand shares worth $5.42M.

Investors who are buying ELVN stock?

As per its latest 13F filing, AMERICAN CENTURY COMPANIES INC increased its stake in ELVN by 297.88% in the last quarter. The institutional holder raised its holding to 45.79 thousand shares having worth more than $705.20K. EXODUSPOINT CAPITAL MANAGEMENT, LP also added 25.51% more shares of ELVN to its portfolio, raising its holding to 60.42 thousand shares of worth $930.39K. WELLINGTON MANAGEMENT GROUP LLP also increased its ELVN shares holding by 19.64% which brought its holding to 129.88 thousand shares worth $2.00M.

ELVN's major insiders: who are they?

The insider with the most stakes in ELVN is RA CAPITAL MANAGEMENT, L.P. , Former 10% owner at the company. Additionally, ELVN stock is highly held by 10 percent owner Leonard Braden Michael and 10 percent owner COMMODORE CAPITAL LP among others.

Did an insider recently sell ELVN stock?

Company executives, directors, and other insiders own 8.88% percent of Enliven Therapeutics, Inc.'s stock. Within the last six months, there have been 25 transaction(s) in which ELVN insiders have sold stock, totaling 274.33K shares. Insiders that have sold shares include COLLINS HELEN LOUISE, HOHL BENJAMIN, and HEYMAN RICHARD A..

Which insider recently purchased ELVN stock?

There have been 0 transaction(s) during the past 6-months in which Enliven Therapeutics, Inc. insiders have bought stock, totalling 0 shares

How much of ELVN does insiders own?

Around 10.75M Enliven Therapeutics, Inc. shares are held by insiders, which represents about 8.88% of ELVN stock.

Who is the insider with the largest stake?

ELVN Former 10% owner, RA CAPITAL MANAGEMENT, L.P. holds the largest portfolio of the company's shares. ELVN shares owned by RA total nearly 2.12 million.

Which institution holds the most shares in ELVN?

AMERICAN CENTURY COMPANIES INC is the largest institutional owner in ELVN which holds 45.79 thousand shares worth $705.20K or 0.07% of the total ELVN shares outstanding followed by NUVEEN, LLC with ownership of 105.45 thousand shares representing 0.17% of the ELVN ownership. HIGHVISTA STRATEGIES LLC is the third largest stakeholder with 82.54 thousand shares or 0.13% of the ownership worth more than $1.27M.

Is Enliven Therapeutics, Inc. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the ELVN is concerned, it is a stock which is optionable.

Is there a short position on ELVN's shares?

Number of ELVN shares short is 5.08M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding ELVN shares are there?

As of today, 59.24M shares of ELVN are outstanding.

Is there many float in ELVN stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, ELVN has 36.32M shares in float.

ELVN short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for ELVN is 11.7.

Enliven Therapeutics (ELVN) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares8.61

Short Percent Of Float12.28

Shares Outstanding59.24M

Shares Float36.32M

Shares Short5.08M

Short Ratio11.7

12.28%

Short % of Float

8.61%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

8.88% Percentage of Shares held by All Insiders

102.25% Percentage of Shares held by All Institutions

112.22% Percentage of Float held by Institutions

184

Number of Institutions Holding Shares

Institutional Ownership

About 102.25% of ELVN shares are held by financial institutions. AMERICAN CENTURY COMPANIES INC is the top corporate investor, holding 45.79K shares valued at $705.20K. A 0.07% stake in Enliven Therapeutics, Inc. is owned by the company. NUVEEN, LLC owns 105.45K shares valued at $1.62M, which translates its holding of 0.17% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Dec 31, 2025	AMERICAN CENTURY COMPANIES INC	0.07%	45.79K	705.2K	34.28K	+297.88%
Dec 31, 2025	NUVEEN, LLC	0.17%	105.45K	1.62M	-2.8K	-2.58%
Dec 31, 2025	HIGHVISTA STRATEGIES LLC	0.13%	82.54K	1.27M	-176.6K	-68.15%
Dec 31, 2025	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.1%	60.42K	930.39K	12.28K	+25.51%
Dec 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.21%	129.88K	2M	21.32K	+19.64%
Dec 31, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.37%	226.77K	3.49M	60K	+35.98%
Dec 31, 2025	NORTHERN TRUST CORP	0.57%	352.24K	5.42M	-42.21K	-10.70%
Dec 31, 2025	STATE STREET CORP	1.7%	1.05M	16.21M	87.73K	+9.09%
Dec 31, 2025	VIRTUS INVESTMENT ADVISERS, INC.	0.03%	15.78K	242.98K	9.99K	+172.65%
Dec 31, 2025	CITIGROUP INC	0.03%	18.49K	284.73K	6.74K	+57.41%
Dec 31, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.03%	19.34K	297.77K	-24.67K	-56.06%
Dec 31, 2025	SQUAREPOINT OPS LLC	0.03%	20.76K	319.75K	-15.08K	-42.08%
Dec 31, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.04%	24.56K	378.16K	0	0
Dec 31, 2025	LEGAL & GENERAL GROUP PLC	0.04%	27.06K	416.71K	-6.71K	-19.86%
Dec 31, 2025	DEUTSCHE BANK AG\	0.05%	31.42K	483.87K	6.23K	+24.74%
Dec 31, 2025	BANK OF AMERICA CORP /DE/	0.05%	32.71K	503.75M	9.17K	+38.94%
Dec 31, 2025	RHUMBLINE ADVISERS	0.08%	50.51K	777.83M	-9.65K	-16.04%
Dec 31, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.09%	55.21K	850.23K	3.53K	+6.82%
Dec 31, 2025	SWISS NATIONAL BANK	0.1%	64.27K	989.8K	1.1K	+1.74%
Dec 31, 2025	LIGHTHOUSE INVESTMENT PARTNERS, LLC	0.1%	65K	1M	65K	+100.00%
Dec 31, 2025	BARCLAYS PLC	0.11%	69.88K	1.08M	13.66K	+24.30%
Dec 31, 2025	BANK OF NEW YORK MELLON CORP	0.18%	110.57K	1.7M	-5.05K	-4.37%
Dec 31, 2025	AVIDITY PARTNERS MANAGEMENT LP	0.23%	140.3K	2.16M	0	0
Dec 31, 2025	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.31%	194.74K	3M	159.96K	+459.92%
Dec 31, 2025	EXOME ASSET MANAGEMENT LLC	0.36%	222.31K	3.42M	222.31K	+100.00%
Dec 31, 2025	GOLDMAN SACHS GROUP INC	0.38%	237.2K	3.65M	-25.07K	-9.56%
Dec 31, 2025	MILLENNIUM MANAGEMENT LLC	0.48%	296.95K	4.57M	-84.46K	-22.14%
Dec 31, 2025	PATIENT SQUARE CAPITAL LP	0.5%	308.14K	4.75M	57.3K	+22.84%
Dec 31, 2025	LOGOS GLOBAL MANAGEMENT LP	0.55%	340K	5.24M	0	0
Dec 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.57%	355.19K	5.47M	-8.01K	-2.21%
Dec 31, 2025	DIMENSIONAL FUND ADVISORS LP	0.64%	398.89K	6.14M	238.43K	+148.59%
Dec 31, 2025	MORGAN STANLEY	0.66%	411.82K	6.34M	153.44K	+59.38%
Dec 31, 2025		0.32%	199.31K	3.07B	199.31K	+100.00%
Dec 31, 2025	CANDRIAM S.C.A.	0.73%	453.02K	6.98M	-156.33K	-25.66%
Dec 31, 2025	JPMORGAN CHASE & CO	0.03%	20.7K	318.79K	-4.12K	-16.59%
Dec 31, 2025	TUDOR INVESTMENT CORP ET AL	0.05%	29.67K	456.96K	13.37K	+82.01%
Dec 31, 2025	JUMP FINANCIAL, LLC	0.07%	45.35K	698.45K	45.35K	+100.00%
Dec 31, 2025	FRANKLIN RESOURCES INC	0.03%	20.17K	310.57K	-410.07K	-95.31%
Dec 31, 2025	JANE STREET GROUP, LLC	0.16%	101.97K	1.57M	101.97K	+100.00%
Dec 31, 2025	BAKER BROS. ADVISORS LP	0.44%	271.41K	4.18M	156.57K	+136.35%
Dec 31, 2025	BLACKSTONE INC.	1.54%	954.95K	14.71M	-365.65K	-27.69%
Dec 31, 2025	5AM VENTURE MANAGEMENT, LLC	1.24%	772.48K	11.9M	0	0
Dec 31, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	1.65%	1.03M	15.79M	1.03M	+100.00%
Dec 31, 2025	CITADEL ADVISORS LLC	2.29%	1.42M	21.93M	263.84K	+22.74%
Dec 31, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	1.29%	798.41K	12.3M	112.3K	+16.37%
Dec 31, 2025	UBS GROUP AG	0.09%	57.87K	891.17K	-21.64K	-27.22%
Dec 31, 2025	XTX TOPCO LTD	0.1%	60.7K	934.81K	60.7K	+100.00%
Dec 31, 2025	WOODLINE PARTNERS LP	0.48%	301.02K	4.64M	524	+0.17%
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.69%	1.05M	16.15M	-36.29K	-3.34%
Dec 31, 2025	NOVO HOLDINGS A/S	2.38%	1.48M	22.79M	53.74K	+3.77%
Dec 31, 2025	POINT72 ASSET MANAGEMENT, L.P.	2.42%	1.5M	23.17M	464.19K	+44.62%
Dec 31, 2025	JANUS HENDERSON GROUP PLC	2.69%	1.67M	25.74M	-121.86K	-6.79%
Dec 31, 2025	VR ADVISER, LLC	5.2%	3.23M	49.69M	0	0
Dec 31, 2025	POLAR CAPITAL HOLDINGS PLC	5.66%	3.51M	54.11M	418.67K	+13.53%
Dec 31, 2025	FAIRMOUNT FUNDS MANAGEMENT LLC	5.98%	3.71M	57.16M	0	0
Dec 31, 2025	VESTAL POINT CAPITAL, LP	6.17%	3.83M	58.98M	2.67M	+230.17%
Dec 31, 2025	COMMODORE CAPITAL LP	7.56%	4.69M	72.27M	0	0
Dec 31, 2025	FMR LLC	11.45%	7.11M	109.46M	-21.56K	-0.30%
Dec 31, 2025	ORBIMED ADVISORS LLC	12.82%	7.96M	122.58M	0	0
Dec 31, 2025	PICTET ASSET MANAGEMENT HOLDING SA	2.1%	1.3M	20.07M	-94.85K	-6.78%
Dec 31, 2025	MARSHALL WACE, LLP	0.6%	371.91K	5.73M	31.42K	+9.23%
Dec 31, 2025	CAPITAL RESEARCH GLOBAL INVESTORS	2.1%	1.3M	20.09M	-11.12K	-0.85%
Dec 31, 2025	VANGUARD GROUP INC	4.51%	2.8M	43.15M	248.65K	+9.74%
Dec 31, 2025	BLACKROCK, INC.	5.82%	3.61M	55.65M	94.8K	+2.69%
Dec 31, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.01%	9.1K	140.09K	-6K	-39.74%
Dec 31, 2025	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.02%	9.67K	148.93K	-712	-6.86%
Dec 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.02%	9.67K	148.95K	528	+5.77%
Dec 31, 2025	PROFUND ADVISORS LLC	0.02%	10.18K	156.76K	10.18K	+100.00%
Dec 31, 2025	LANDSCAPE CAPITAL MANAGEMENT, L.L.C.	0.02%	10.3K	158.64K	0	0
Dec 31, 2025	QUEST PARTNERS LLC	0.02%	10.34K	159.19K	5.64K	+119.89%
Dec 31, 2025	STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM	0.02%	10.48K	161.39K	0	0
Dec 31, 2025	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0.02%	11.16K	171.9K	123	+1.11%
Dec 31, 2025	FOX RUN MANAGEMENT, L.L.C.	0.02%	12.43K	191.45K	12.43K	+100.00%
Dec 31, 2025	SG AMERICAS SECURITIES, LLC	0.02%	14.04K	216K	-8.21K	-36.90%
Dec 31, 2025	AXQ CAPITAL, LP	0.02%	14.24K	219.36K	14.24K	+100.00%
Dec 31, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.03%	16.73K	257.63K	2.26K	+15.59%
Dec 31, 2025	PRUDENTIAL FINANCIAL INC	0.06%	35.58K	547.93K	35.58K	+100.00%
Dec 31, 2025	WELLS FARGO & COMPANY/MN	0.07%	43.06K	663.06K	17.23K	+66.73%
Sep 30, 2025	CITADEL ADVISORS LLC	1.87%	1.16M	23.76M	-309.92K	-21.08%
Sep 30, 2025	KLP KAPITALFORVALTNING AS	0.01%	6.8K	139.2K	0	0
Sep 30, 2025	QUEST PARTNERS LLC	0.01%	4.7K	96.23K	4.7K	+100.00%
Sep 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0.01%	3.64K	74.55K	-25.91K	-87.67%
Sep 30, 2025	AMERITAS INVESTMENT PARTNERS, INC.	0.01%	3.45K	70.6K	0	0
Sep 30, 2025	BIT CAPITAL GMBH	0.01%	3.18K	65.12K	0	0
Sep 30, 2025	MIRAE ASSET GLOBAL INVESTMENTS CO., LTD.	0%	2.29K	46.88K	394	+20.78%
Sep 30, 2025	LOGOS GLOBAL MANAGEMENT LP	0.55%	340K	6.96M	-10K	-2.86%
Sep 30, 2025	WOODLINE PARTNERS LP	0.48%	300.5K	6.15M	-800.16K	-72.70%
Sep 30, 2025	CORMORANT ASSET MANAGEMENT, LP	0.32%	200K	4.09M	0	0
Sep 30, 2025	FMR LLC	11.48%	7.13M	145.93M	-430.71K	-5.70%
Sep 30, 2025	NEOS INVESTMENT MANAGEMENT LLC	0.08%	40.31K	825.23K	7.74K	+23.74%
Sep 30, 2025	TEMA ETFS LLC	0.08%	40.31K	825.23K	7.74K	+23.74%
Sep 30, 2025	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.07%	34.78K	711.93M	34.78K	+100.00%
Sep 30, 2025	LEGAL & GENERAL GROUP PLC	0.06%	33.77K	691.17K	1.54K	+4.78%
Sep 30, 2025	TD ASSET MANAGEMENT INC	0.05%	27.52K	563.29K	-39.39K	-58.87%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0.05%	25.82K	528.62K	9.17K	+55.04%
Sep 30, 2025	DEUTSCHE BANK AG\	0.05%	25.19K	515.62K	2.71K	+12.08%
Sep 30, 2025	JPMORGAN CHASE & CO	0.05%	24.82K	508.03K	5.75K	+30.18%
Sep 30, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.05%	24.56K	502.66K	3.35K	+15.77%
Sep 30, 2025	INVESCO LTD.	0.04%	23.1K	472.78K	1.14K	+5.19%
Sep 30, 2025	SG AMERICAS SECURITIES, LLC	0.04%	22.24K	455K	-14.13K	-38.85%
Sep 30, 2025	WINTON GROUP LTD	0.03%	16.46K	336.9K	16.46K	+100.00%
Sep 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.03%	15.1K	309.04K	5.3K	+54.10%
Sep 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.03%	14.47K	296.26K	-29	-0.20%
Sep 30, 2025	CITIGROUP INC	0.02%	11.75K	240.44K	-6.39K	-35.24%
Sep 30, 2025	AMERICAN CENTURY COMPANIES INC	0.02%	11.51K	235.59K	11.51K	+100.00%
Sep 30, 2025	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0.02%	11.04K	225.97K	2.74K	+32.98%
Sep 30, 2025	FEDERATED HERMES, INC.	0.02%	10.81K	221.3K	-5.29K	-32.84%
Sep 30, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.02%	10.68K	218.52K	675	+6.75%
Sep 30, 2025	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.02%	10.38K	212.54K	528	+5.36%
Sep 30, 2025	LANDSCAPE CAPITAL MANAGEMENT, L.L.C.	0.02%	10.3K	210.86K	10.3K	+100.00%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.02%	9.14K	187.18K	5.42K	+145.67%
Sep 30, 2025	QUANTBOT TECHNOLOGIES LP	0%	2.15K	43.93K	-2.33K	-52.07%
Sep 30, 2025	GF FUND MANAGEMENT CO. LTD.	0%	1.27K	26.08K	23	+1.84%
Sep 30, 2025	AMALGAMATED BANK	0%	1.22K	25K	0	0
Sep 30, 2025	FRANKLIN RESOURCES INC	0.69%	430.24K	8.81M	0	0
Sep 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.64%	400K	8.19M	0	0
Sep 30, 2025	NORTHERN TRUST CORP	0.64%	394.45K	8.07M	69.82K	+21.51%
Sep 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	0.37%	231.3K	4.74M	-296.95K	-56.21%
Sep 30, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.27%	166.77K	3.41M	38.25K	+29.76%
Sep 30, 2025	DIMENSIONAL FUND ADVISORS LP	0.26%	160.46K	3.28M	113.61K	+242.49%
Sep 30, 2025	PFM HEALTH SCIENCES, LP	0.25%	156.46K	3.2M	156.46K	+100.00%
Sep 30, 2025	5AM VENTURE MANAGEMENT, LLC	1.24%	772.48K	15.81M	0	0
Sep 30, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	1.1%	686.11K	14.04M	-15.3K	-2.18%
Sep 30, 2025	CANDRIAM S.C.A.	0.98%	609.35K	12.47M	192.7K	+46.25%
Sep 30, 2025	MILLENNIUM MANAGEMENT LLC	0.61%	381.41K	7.81M	62.96K	+19.77%
Sep 30, 2025	BAKER BROS. ADVISORS LP	0.18%	114.83K	2.35M	0	0
Sep 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.17%	108.56K	2.22M	14.55K	+15.47%
Sep 30, 2025	COMMODORE CAPITAL LP	7.56%	4.69M	96.06M	0	0
Sep 30, 2025	FAIRMOUNT FUNDS MANAGEMENT LLC	5.98%	3.71M	75.97M	0	0
Sep 30, 2025	BLACKROCK, INC.	5.67%	3.52M	72.02M	551.39K	+18.58%
Sep 30, 2025	VR ADVISER, LLC	5.2%	3.23M	66.04M	-800K	-19.87%
Sep 30, 2025	VESTAL POINT CAPITAL, LP	1.87%	1.16M	23.75M	910K	+364.00%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.75%	1.09M	22.21M	202.26K	+22.91%
Sep 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	1.68%	1.04M	21.3M	-312.67K	-23.11%
Sep 30, 2025	STATE STREET CORP	1.55%	965.14K	19.76M	148.9K	+18.24%
Sep 30, 2025	MARSHALL WACE, LLP	0.55%	340.48K	6.97M	7.15K	+2.14%
Sep 30, 2025	CAPITAL RESEARCH GLOBAL INVESTORS	2.12%	1.32M	26.93M	0	0
Sep 30, 2025	FIRST TURN MANAGEMENT, LLC	1.26%	783.41K	16.04M	273.42K	+53.61%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.58%	363.2K	7.43M	57.54K	+18.83%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	0.42%	262.27K	5.37M	72.77K	+38.40%
Sep 30, 2025	HIGHVISTA STRATEGIES LLC	0.42%	259.14K	5.3M	117.62K	+83.11%
Sep 30, 2025	SWISS NATIONAL BANK	0.1%	63.17K	1.29M	1.3K	+2.10%
Sep 30, 2025	MORGAN STANLEY	0.42%	258.38K	5.29M	3.54K	+1.39%
Sep 30, 2025	PATIENT SQUARE CAPITAL LP	0.4%	250.84K	5.13M	5K	+2.03%
Sep 30, 2025	AVIDITY PARTNERS MANAGEMENT LP	0.23%	140.3K	2.87M	129K	+1,141.59%
Sep 30, 2025	AMERIPRISE FINANCIAL INC	0.2%	123.34K	2.52M	64.09K	+108.18%
Sep 30, 2025	NUVEEN, LLC	0.17%	108.24K	2.22M	18.53K	+20.66%
Sep 30, 2025	UBS GROUP AG	0.13%	79.51K	1.63M	-58.77K	-42.50%
Sep 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.12%	73K	1.49M	-23K	-23.96%
Sep 30, 2025	POLAR CAPITAL HOLDINGS PLC	4.98%	3.1M	63.35M	44.71K	+1.47%
Sep 30, 2025	VANGUARD GROUP INC	4.11%	2.55M	52.26M	142.38K	+5.91%
Sep 30, 2025	JANUS HENDERSON GROUP PLC	2.89%	1.79M	36.7M	77.17K	+4.50%
Sep 30, 2025	NOVO HOLDINGS A/S	2.3%	1.43M	29.2M	341.83K	+31.52%
Sep 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	2.25%	1.4M	28.62M	430.59K	+44.50%
Sep 30, 2025	BLACKSTONE INC.	2.13%	1.32M	27.03M	0	0
Sep 30, 2025	DUQUESNE FAMILY OFFICE LLC	1.53%	947.41K	19.39M	484.41K	+104.62%
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.19%	115.62K	2.37M	17.49K	+17.82%
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.11%	59K	1.21M	35.1K	+146.86%
Sep 30, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.1%	51.68K	1.06M	-31.37K	-37.77%
Sep 30, 2025	TREXQUANT INVESTMENT LP	0.1%	50.49K	1.03M	24.97K	+97.80%
Sep 30, 2025	BARCLAYS PLC	0.11%	70.69K	1.45M	-2.1K	-2.88%
Sep 30, 2025	ORBIMED ADVISORS LLC	12.82%	7.96M	162.93M	0	0
Sep 30, 2025	RHUMBLINE ADVISERS	0.12%	60.16K	1.23M	9.88K	+19.65%
Jun 30, 2025	BAKER BROS. ADVISORS LP	0.22%	114.83K	2.3M	0	0
Jun 30, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.16%	83.05K	1.67M	47.16K	+131.36%
Jun 30, 2025		0.17%	89.71K	1.8M	-14.39K	-13.82%
Jun 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.18%	96K	1.93M	-354K	-78.67%
Jun 30, 2025	BANK OF NEW YORK MELLON CORP	0.19%	98.13K	1.97M	4.56K	+4.88%
Jun 30, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.25%	128.52K	2.58M	16.77K	+15.01%
Jun 30, 2025	UBS GROUP AG	0.27%	138.28K	2.77M	67.84K	+96.32%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.36%	189.51K	3.8M	-22.25K	-10.51%
Jun 30, 2025	CORMORANT ASSET MANAGEMENT, LP	0.38%	200K	4.01M	-50K	-20.00%
Jun 30, 2025	ORBIMED ADVISORS LLC	15.28%	7.96M	159.67M	0	0
Jun 30, 2025	FMR LLC	14.51%	7.56M	151.65M	950.37K	+14.38%
Jun 30, 2025	COMMODORE CAPITAL LP	9.01%	4.69M	94.14M	17.81K	+0.38%
Jun 30, 2025	VR ADVISER, LLC	7.73%	4.03M	80.77M	0	0
Jun 30, 2025	POLAR CAPITAL HOLDINGS PLC	5.85%	3.05M	61.19M	685K	+28.96%
Jun 30, 2025	AVIDITY PARTNERS MANAGEMENT LP	0.02%	11.3K	226.68K	0	0
Jun 30, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.02%	10K	200.6K	10K	+100.00%
Jun 30, 2025	FAIRMOUNT FUNDS MANAGEMENT LLC	7.12%	3.71M	74.45M	508.65K	+15.88%
Jun 30, 2025	BLACKROCK, INC.	5.69%	2.97M	59.52M	-31K	-1.03%
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.01%	528.25K	10.6M	512.09K	+3,168.87%
Jun 30, 2025	FIRST TURN MANAGEMENT, LLC	0.98%	509.99K	10.23M	-25.11K	-4.69%
Jun 30, 2025	TCG CROSSOVER MANAGEMENT, LLC	0.96%	498K	9.99M	498K	+100.00%
Jun 30, 2025	VANGUARD GROUP INC	4.63%	2.41M	48.36M	438.4K	+22.23%
Jun 30, 2025	JANUS HENDERSON GROUP PLC	3.29%	1.72M	34.41M	145.91K	+9.29%
Jun 30, 2025	CITADEL ADVISORS LLC	2.82%	1.47M	29.5M	347.29K	+30.92%
Jun 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	2.6%	1.35M	27.14M	1.21M	+867.05%
Jun 30, 2025	BLACKSTONE INC.	2.53%	1.32M	26.49M	558.29K	+73.24%
Jun 30, 2025	CAPITAL RESEARCH GLOBAL INVESTORS	2.52%	1.32M	26.39M	1.32M	+100.00%
Jun 30, 2025	STATE STREET CORP	1.57%	816.24K	16.37M	35.34K	+4.53%
Jun 30, 2025	CANDRIAM S.C.A.	0.8%	416.65K	8.36M	416.65K	+100.00%
Jun 30, 2025	WOODLINE PARTNERS LP	2.11%	1.1M	22.08M	295.5K	+36.70%
Jun 30, 2025	NOVO HOLDINGS A/S	2.08%	1.08M	21.75M	1.08M	+100.00%
Jun 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	1.86%	967.5K	19.41M	0	0
Jun 30, 2025	NUVEEN, LLC	0.17%	89.71K	1.8M	-14.39K	-13.82%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.69%	882.75K	17.71M	63.58K	+7.76%
Jun 30, 2025	RA CAPITAL MANAGEMENT, L.P.	1.63%	848.99K	17.03M	0	0
Jun 30, 2025	5AM VENTURE MANAGEMENT, LLC	1.48%	772.48K	15.5M	-550K	-41.59%
Jun 30, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	1.35%	701.41K	14.07M	235.54K	+50.56%
Jun 30, 2025	DUQUESNE FAMILY OFFICE LLC	0.89%	463K	9.29M	463K	+100.00%
Jun 30, 2025	FRANKLIN RESOURCES INC	0.83%	430.24K	8.63M	410.03K	+2,029.27%
Jun 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.77%	400K	8.02M	400K	+100.00%
Jun 30, 2025	LOGOS GLOBAL MANAGEMENT LP	0.67%	350K	7.02M	110K	+45.83%
Jun 30, 2025	NORTHERN TRUST CORP	0.62%	324.63K	6.51M	-14.02K	-4.14%
Jun 30, 2025	MILLENNIUM MANAGEMENT LLC	0.61%	318.45K	6.39M	185.56K	+139.64%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.59%	305.66K	6.13M	46.12K	+17.77%
Jun 30, 2025	ALLY BRIDGE GROUP (NY) LLC	0.54%	281.39K	5.64M	111.62K	+65.75%
Jun 30, 2025	MARSHALL WACE, LLP	0.64%	333.33K	6.69M	322.17K	+2,886.85%
Jun 30, 2025	VESTAL POINT CAPITAL, LP	0.48%	250K	5.02M	250K	+100.00%
Jun 30, 2025	PATIENT SQUARE CAPITAL LP	0.47%	245.84K	4.93M	-8K	-3.15%
Jun 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.18%	94.01K	1.89M	9.31K	+10.99%
Jun 30, 2025	HIGHVISTA STRATEGIES LLC	0.27%	141.52K	2.84M	29.06K	+25.84%
Jun 30, 2025	ROYAL BANK OF CANADA	0.13%	67.86K	1.36M	62.69K	+1,211.13%
Jun 30, 2025	MORGAN STANLEY	0.49%	254.85K	5.11M	173.53K	+213.41%
Jun 30, 2025	XTX TOPCO LTD	0.02%	11.36K	227.92K	-10.49K	-48.00%
Jun 30, 2025	CAXTON CORP	0.03%	13.1K	262.74K	13.1K	+100.00%
Jun 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.03%	14.5K	290.91K	-5.6K	-27.86%
Jun 30, 2025	MIRAE ASSET GLOBAL ETFS HOLDINGS LTD.	0.03%	17.66K	354.18K	-4.07K	-18.74%
Jun 30, 2025	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.03%	17.66K	354.18K	17.66K	+100.00%
Jun 30, 2025	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0.04%	20.33K	407.82M	-584	-2.79%
Jun 30, 2025	TREXQUANT INVESTMENT LP	0.05%	25.53K	512.07K	25.53K	+100.00%
Jun 30, 2025	SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC	0.05%	28.33K	568.38K	0	0
Jun 30, 2025	NEOS INVESTMENT MANAGEMENT LLC	0.06%	32.58K	653.54K	8.93K	+37.77%
Jun 30, 2025	ALLIANCEBERNSTEIN L.P.	0.07%	36.84K	739.01M	0	0
Jun 30, 2025	WEISS ASSET MANAGEMENT LP	0.09%	47.62K	955.3K	47.62K	+100.00%
Jun 30, 2025	STATE OF WISCONSIN INVESTMENT BOARD	0.11%	56.78K	1.14M	11.03K	+24.10%
Jun 30, 2025	TD ASSET MANAGEMENT INC	0.13%	66.91K	1.34M	66.91K	+100.00%
Jun 30, 2025	SUSQUEHANNA PORTFOLIO STRATEGIES, LLC	0.13%	67.68K	1.36M	67.68K	+100.00%
Jun 30, 2025	BARCLAYS PLC	0.14%	72.78K	1.46M	22.43K	+44.54%
Mar 31, 2025	BAKER BROS. ADVISORS LP	0.23%	114.83K	2.26M	0	0
Mar 31, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	0.93%	465.87K	9.17M	37.3K	+8.70%
Mar 31, 2025	COMMODORE CAPITAL LP	9.38%	4.68M	92M	470K	+11.18%
Mar 31, 2025	FMR LLC	13.21%	6.61M	130.08M	113.66K	+1.75%
Mar 31, 2025	BARCLAYS PLC	0.1%	50.36K	991K	-14.21K	-22.00%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.52%	259.54K	5.11M	-2.35K	-0.90%
Mar 31, 2025	ACUTA CAPITAL PARTNERS, LLC	0.53%	265.27K	5.22M	-2.1K	-0.79%
Mar 31, 2025	IKARIAN CAPITAL, LLC	0.58%	289.54K	5.7M	-105K	-26.61%
Mar 31, 2025	ORBIMED ADVISORS LLC	15.96%	7.96M	156.64M	0	0
Mar 31, 2025	STEMPOINT CAPITAL LP	0.24%	120.43K	2.37M	23.71K	+24.52%
Mar 31, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0.21%	105.54K	2.08M	105.47K	+148,550.70%
Mar 31, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.22%	111.74K	2.2M	111.74K	+100.00%
Mar 31, 2025	RHUMBLINE ADVISERS	0.1%	52.5K	1.03M	2.47K	+4.93%
Mar 31, 2025	FEDERATED HERMES, INC.	0.14%	69.05K	1.36M	-48.5K	-41.26%
Mar 31, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.15%	76.98K	1.51M	-27.92K	-26.61%
Mar 31, 2025	CITADEL ADVISORS LLC	2.24%	1.12M	22.1M	-615.39K	-35.40%
Mar 31, 2025	5AM VENTURE MANAGEMENT, LLC	2.65%	1.32M	26.03M	-307.29K	-18.85%
Mar 31, 2025	JANUS HENDERSON GROUP PLC	3.14%	1.57M	33.05M	238.63K	+17.92%
Mar 31, 2025	SWISS NATIONAL BANK	0.08%	41.87K	824.06K	0	0
Mar 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.09%	44.92K	883.93K	29.39K	+189.21%
Mar 31, 2025	STATE OF WISCONSIN INVESTMENT BOARD	0.09%	45.76K	900.48K	18.92K	+70.51%
Mar 31, 2025	LOGOS GLOBAL MANAGEMENT LP	0.48%	240K	4.72M	100K	+71.43%
Mar 31, 2025	CORMORANT ASSET MANAGEMENT, LP	0.5%	250K	4.92M	0	0
Mar 31, 2025	PATIENT SQUARE CAPITAL LP	0.51%	253.84K	5M	29.8K	+13.30%
Mar 31, 2025	NORTHERN TRUST CORP	0.68%	338.65K	6.66M	7.15K	+2.16%
Mar 31, 2025	FIRST TURN MANAGEMENT, LLC	1.07%	535.09K	10.53M	0	0
Mar 31, 2025	BLACKSTONE INC.	1.52%	762.31K	15M	388.98K	+104.20%
Mar 31, 2025	HIGHVISTA STRATEGIES LLC	0.22%	112.46K	2.21M	0	0
Mar 31, 2025	LORD, ABBETT & CO. LLC	0.39%	197.28K	3.88M	-188.93K	-48.92%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.42%	211.75K	4.17M	80.51K	+61.34%
Mar 31, 2025	STATE STREET CORP	1.56%	780.9K	15.37M	-20.93K	-2.61%
Mar 31, 2025	WOODLINE PARTNERS LP	1.61%	805.16K	15.85M	-765	-0.09%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.64%	819.17K	16.12M	56.46K	+7.40%
Mar 31, 2025	RA CAPITAL MANAGEMENT, L.P.	1.7%	848.99K	16.71M	0	0
Mar 31, 2025	VANGUARD GROUP INC	3.94%	1.97M	38.81M	-3.42K	-0.17%
Mar 31, 2025	POLAR CAPITAL HOLDINGS PLC	4.73%	2.37M	46.55M	-24.37K	-1.02%
Mar 31, 2025	BLACKROCK, INC.	5.99%	3M	59M	33K	+1.11%
Mar 31, 2025	FAIRMOUNT FUNDS MANAGEMENT LLC	6.42%	3.2M	63.03M	0	0
Mar 31, 2025	VR ADVISER, LLC	8.08%	4.03M	79.24M	0	0
Mar 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.17%	84.7K	1.67M	3.78K	+4.68%
Mar 31, 2025	BANK OF NEW YORK MELLON CORP	0.19%	93.57K	1.84M	3.99K	+4.46%
Mar 31, 2025	UBS GROUP AG	0.14%	70.44K	1.39M	-16.75K	-19.21%
Mar 31, 2025		0.21%	104.1K	2.05M	104.1K	+100.00%
Mar 31, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.9%	450K	8.86M	-200K	-30.77%
Mar 31, 2025	ALLY BRIDGE GROUP (NY) LLC	0.34%	169.77K	3.34M	28.06K	+19.80%
Mar 31, 2025	MORGAN STANLEY	0.16%	81.32K	1.6M	-29.29K	-26.48%
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	0.27%	132.89K	2.62M	82.08K	+161.57%
Mar 31, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.28%	139.92K	2.75M	139.92K	+100.00%
Mar 31, 2025	PICTET ASSET MANAGEMENT HOLDING SA	1.93%	967.5K	19.04M	-4.79K	-0.49%

Insiders

Among the ELVN insiders holding of 8.88% of the stake in company, RA CAPITAL MANAGEMENT, L.P., Former 10% owner, holds the largest shares of 2.12M. LEONARD BRADEN MICHAEL, 10 percent owner, is the second largest ELVN insider with ownership of 1.77M shares. COMMODORE CAPITAL LP, 10 percent owner, stands third with possession of 1.45M shares of that stake.

Insiders	Designation	Shares Held
RA CAPITAL MANAGEMENT, L.P.	Former 10% owner	2.12M
LEONARD BRADEN MICHAEL	10 percent owner	1.77M
COMMODORE CAPITAL LP	10 percent owner	1.45M
KINTZ SAMUEL	PRESIDENT AND CEO	890.39K
LYSSIKATOS JOSEPH P	CHIEF SCIENTIFIC OFFICER	740.19K
5AM PARTNERS VI, LLC	10 percent owner	635.34K
ORBIMED ADVISORS LLC		254.81K
GUPTA RISHI		254.81K
PATEL ANISH	CHIEF OPERATING OFFICER	215.01K
HOHL BENJAMIN	CHIEF FINANCIAL OFFICER	51K
GRAY MICHAEL	CFO & COO	27.61K
PHILLIPS ANDREW JOHN	director	27.57K
BAUER JAKE	director	27.57K
SCHWAB ANDREW J.	director, 10 percent owner	27.57K
DERYNCK MIKA K	director	27.57K
COLLINS HELEN LOUISE	CHIEF MEDICAL OFFICER	25K
HEYMAN RICHARD A.	director	22.65K
BALLAL RAHUL D.	director	22.34K

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Mar 17, 2026	COLLINS HELEN LOUISE	SALE	27.76	5K	138.8K	25K
Mar 10, 2026	COLLINS HELEN LOUISE	SALE	30.19	10.13K	305.83K	25K
Mar 09, 2026	COLLINS HELEN LOUISE	SALE	30.02	29.87K	896.81K	25K
Mar 06, 2026	HOHL BENJAMIN	SALE	29.58	10K	295.84K	51K
Feb 17, 2026	COLLINS HELEN LOUISE	SALE	26.17	45K	1.18M	25K
Feb 17, 2026	HEYMAN RICHARD A.	SALE	26.18	1.23K	32.2K	22.65K
Feb 06, 2026	LYSSIKATOS JOSEPH P	SALE	29.04	5K	145.22K	740.19K
Jan 20, 2026	HEYMAN RICHARD A.	SALE	26.96	718	19.35K	23.88K
Jan 20, 2026	LYSSIKATOS JOSEPH P	SALE	26.90	14.51K	390.28K	745.19K
Jan 09, 2026	PATEL ANISH	SALE	28.50	243	6.93K	215.01K
Jan 09, 2026	LYSSIKATOS JOSEPH P	SALE	29.13	50K	1.46M	765.19K
Jan 09, 2026	HEYMAN RICHARD A.	SALE	25.00	4.29K	107.13K	25.11K
Jan 08, 2026	HEYMAN RICHARD A.	SALE	25.00	1.62K	40.5K	25.55K
Jan 08, 2026	LYSSIKATOS JOSEPH P	SALE	24.92	33.8K	842.47K	856.39K
Dec 19, 2025	LYSSIKATOS JOSEPH P	SALE	16.84	5K	84.21K	897.69K
Dec 08, 2025	PATEL ANISH	SALE	21.78	1.71K	37.13K	263.31K
Nov 19, 2025	LYSSIKATOS JOSEPH P	SALE	23.09	492	11.36K	902.69K
Nov 17, 2025	KINTZ SAMUEL	SALE	21.82	12.5K	272.74K	890.39K
Nov 07, 2025	PATEL ANISH	SALE	17.94	613	11K	269.97K
Oct 20, 2025	LYSSIKATOS JOSEPH P	SALE	22.08	12.5K	276.03K	915.19K
Oct 17, 2025	KINTZ SAMUEL	SALE	21.33	12.5K	266.65K	902.89K
Oct 07, 2025	PATEL ANISH	SALE	20.10	6.67K	133.99K	276.64K
Sep 29, 2025	HOHL BENJAMIN	SALE	20.40	3.25K	66.29K	23K
Sep 26, 2025	KINTZ SAMUEL	SALE	20.06	3.7K	74.23K	915.39K
Sep 26, 2025	LYSSIKATOS JOSEPH P	SALE	20.25	4K	81.01K	927.69K
Sep 23, 2025	KINTZ SAMUEL	SALE	20.03	2.8K	56.08K	919.09K
Sep 23, 2025	LYSSIKATOS JOSEPH P	SALE	20.03	1.5K	30.05K	931.69K
Sep 19, 2025	KINTZ SAMUEL	SALE	20.25	1K	20.25K	921.89K
Sep 19, 2025	LYSSIKATOS JOSEPH P	SALE	20.02	2.13K	42.63K	933.19K
Sep 17, 2025	KINTZ SAMUEL	SALE	19.09	5K	95.47K	922.89K
Sep 08, 2025	PATEL ANISH	SALE	20.24	6.67K	134.96K	283.31K
Aug 27, 2025	HOHL BENJAMIN	SALE	20.63	3.25K	67.04K	23K
Aug 21, 2025	LYSSIKATOS JOSEPH P	SALE	20.01	7.5K	150.1K	940.19K
Aug 20, 2025	KINTZ SAMUEL	SALE	20.00	1.52K	30.34K	927.89K
Aug 19, 2025	LYSSIKATOS JOSEPH P	SALE	19.62	5K	98.12K	947.69K
Aug 19, 2025	KINTZ SAMUEL	SALE	20.00	590	11.8K	929.41K
Aug 18, 2025	KINTZ SAMUEL	SALE	20.02	10.39K	208.11K	930K
Jul 28, 2025	HOHL BENJAMIN	SALE	21.30	65	1.38K	23K
Jul 21, 2025	LYSSIKATOS JOSEPH P	SALE	22.90	576	13.19K	952.69K
Jul 17, 2025	KINTZ SAMUEL	SALE	23.37	3.66K	85.61K	940.39K
Jul 10, 2025	HOHL BENJAMIN	SALE	22.66	1K	22.66K	23K
Jul 07, 2025	PATEL ANISH	SALE	20.69	305	6.31K	296.64K
Jun 27, 2025	HOHL BENJAMIN	SALE	21.66	198	4.29K	23K
Jun 20, 2025	LYSSIKATOS JOSEPH P	SALE	21.40	12.5K	267.46K	965.19K
Jun 17, 2025	KINTZ SAMUEL	SALE	22.75	2K	45.45K	952.89K
Jun 13, 2025	HOHL BENJAMIN	SALE	22.55	3K	67.66K	23K
Jun 09, 2025	PATEL ANISH	SALE	21.16	60	1.27K	303.31K
Jun 03, 2025	KINTZ SAMUEL	SALE	20.05	7.5K	150.35K	965.39K
Jun 03, 2025	LYSSIKATOS JOSEPH P	SALE	20.03	7.5K	150.22K	977.69K
May 27, 2025	HOHL BENJAMIN	SALE	16.18	3.25K	52.59K	23K
May 19, 2025	LYSSIKATOS JOSEPH P	SALE	16.31	5K	81.53K	985.19K
May 19, 2025	KINTZ SAMUEL	SALE	16.49	5K	82.45K	972.89K
May 07, 2025	PATEL ANISH	SALE	19.87	104	2.07K	309.98K
May 02, 2025	KINTZ SAMUEL	SALE	20.00	2.17K	43.41K	977.89K
May 02, 2025	LYSSIKATOS JOSEPH P	SALE	20.01	2.47K	49.42K	990.19K
May 01, 2025	KINTZ SAMUEL	SALE	20.08	5.33K	107.01K	980.06K
May 01, 2025	LYSSIKATOS JOSEPH P	SALE	20.07	5.03K	100.97K	992.66K
Apr 28, 2025	HOHL BENJAMIN	SALE	19.12	69	1.32K	23K
Apr 21, 2025	LYSSIKATOS JOSEPH P	SALE	16.72	330	5.52K	997.69K
Apr 17, 2025	KINTZ SAMUEL	SALE	16.42	5K	82.1K	985.39K
Apr 07, 2025	PATEL ANISH	SALE	19.27	148	2.85K	316.64K
Mar 27, 2025	HOHL BENJAMIN	SALE	21.33	3.25K	69.32K	23K
Mar 24, 2025	HOHL BENJAMIN	SALE	22.50	1K	22.5K	23K
Mar 19, 2025	LYSSIKATOS JOSEPH P	SALE	20.61	12.5K	257.58K	1M
Mar 17, 2025	KINTZ SAMUEL	SALE	20.83	12.5K	260.32K	990.39K
Mar 07, 2025	PATEL ANISH	SALE	21.44	6.67K	142.94K	323.31K
Feb 27, 2025	HOHL BENJAMIN	SALE	20.41	3.25K	66.33K	13K
Feb 07, 2025	PATEL ANISH	SALE	21.93	6.67K	146.21K	329.98K
Feb 05, 2025	HOHL BENJAMIN	SALE	22.52	1K	22.52K	13K
Jan 27, 2025	HOHL BENJAMIN	SALE	21.59	3.25K	70.18K	13K
Jan 07, 2025	PATEL ANISH	SALE	24.56	1.44K	35.37K	0
Jan 03, 2025	HOHL BENJAMIN	SALE	25.04	1K	25.04K	13K
Dec 30, 2024	HOHL BENJAMIN	SALE	22.51	900	20.26K	0
Dec 27, 2024	HOHL BENJAMIN	SALE	22.15	3.35K	74.22K	0
Nov 27, 2024	HOHL BENJAMIN	SALE	25.38	1K	25.38K	0
Oct 28, 2024	HOHL BENJAMIN	SALE	29.11	650	18.92K	0
Oct 18, 2024	KINTZ SAMUEL	SALE	30.00	924	27.72K	1M
Oct 18, 2024	HOHL BENJAMIN	SALE	30.00	814	24.42K	0
Oct 18, 2024	HEYMAN RICHARD A.	SALE	30.00	753	22.59K	27.17K
Oct 18, 2024	COLLINS HELEN LOUISE	SALE	30.00	816	24.48K	0
Oct 18, 2024	LYSSIKATOS JOSEPH P	SALE	30.00	847	25.41K	1.02M
Oct 18, 2024	PATEL ANISH	SALE	30.00	716	21.48K	343.31K
Oct 15, 2024	HEYMAN RICHARD A.	SALE	27.67	1.27K	35.14K	124.49K
Oct 09, 2024	LYSSIKATOS JOSEPH P	SALE	28.52	3.59K	102.36K	1.02M
Oct 09, 2024	KINTZ SAMUEL	SALE	28.53	2.83K	80.73K	1M
Oct 08, 2024	KINTZ SAMUEL	SALE	28.51	100	2.85K	1.02M
Oct 08, 2024	LYSSIKATOS JOSEPH P	SALE	28.51	100	2.85K	1.05M
Oct 08, 2024	BALLAL RAHUL D.	SALE	28.17	10.42K	293.56K	22.34K
Oct 07, 2024	KINTZ SAMUEL	SALE	27.50	2.73K	75.08K	1.03M
Oct 07, 2024	LYSSIKATOS JOSEPH P	SALE	27.61	2.71K	74.73K	1.07M
Oct 07, 2024	HOHL BENJAMIN	SALE	27.51	1.27K	34.94K	0
Oct 04, 2024	HEYMAN RICHARD A.	SALE	27.51	2.83K	77.7K	125.76K
Oct 04, 2024	HOHL BENJAMIN	SALE	27.51	10.22K	281.08K	0
Oct 04, 2024	KINTZ SAMUEL	SALE	27.51	12.21K	335.79K	1.04M
Oct 04, 2024	LYSSIKATOS JOSEPH P	SALE	27.51	7.52K	206.94K	1.07M
Oct 01, 2024	KINTZ SAMUEL	SALE	27.54	526	14.48K	1.05M
Oct 01, 2024	LYSSIKATOS JOSEPH P	SALE	27.54	527	14.51K	1.08M
Oct 01, 2024	HOHL BENJAMIN	SALE	27.54	521	14.35K	0
Oct 01, 2024	HEYMAN RICHARD A.	SALE	27.54	518	14.26K	128.59K
Sep 30, 2024	HOHL BENJAMIN	SALE	25.33	2K	50.67K	0
Sep 27, 2024	HOHL BENJAMIN	SALE	24.27	4.25K	103.16K	0
Sep 16, 2024	HEYMAN RICHARD A.	SALE	22.41	1.27K	28.46K	129.1K
Aug 29, 2024	LYSSIKATOS JOSEPH P	SALE	23.08	50	1.15K	1.08M
Aug 27, 2024	HOHL BENJAMIN	SALE	22.54	4.25K	95.78K	0
Aug 26, 2024	KINTZ SAMUEL	SALE	22.89	12K	274.72K	1.05M
Aug 15, 2024	HEYMAN RICHARD A.	SALE	23.70	620	14.7K	130.37K
Jul 31, 2024	HEYMAN RICHARD A.	SALE	27.50	649	17.85K	27.92K
Jul 31, 2024	LYSSIKATOS JOSEPH P	SALE	27.56	3.1K	85.4K	1.09M
Jul 31, 2024	KINTZ SAMUEL	SALE	27.56	2.27K	62.56K	1.06M
Jul 31, 2024	HOHL BENJAMIN	SALE	27.53	991	27.28K	0
Jul 29, 2024	HOHL BENJAMIN	SALE	27.44	61	1.67K	0
Jul 29, 2024	LYSSIKATOS JOSEPH P	SALE	27.43	203	5.57K	1.09M
Jul 25, 2024	KINTZ SAMUEL	SALE	25.83	43	1.11K	1.06M
Jul 16, 2024	PATEL ANISH	SALE	25.01	1.55K	38.69K	344.03K
Jul 15, 2024	PATEL ANISH	SALE	25.05	30.98K	776.04K	345.57K
Jul 15, 2024	HEYMAN RICHARD A.	SALE	24.80	1.27K	31.5K	133.35K
Jul 12, 2024	PATEL ANISH	SALE	25.07	17.48K	438.09K	376.55K
Jul 12, 2024	HOHL BENJAMIN	SALE	25.07	3K	75.2K	0
Jul 01, 2024	LYSSIKATOS JOSEPH P	SALE	22.89	12K	274.74K	1.11M
Jun 27, 2024	HOHL BENJAMIN	SALE	23.43	1.14K	26.71K	0
Jun 25, 2024	KINTZ SAMUEL	SALE	22.30	578	12.89K	1.08M
Jun 17, 2024	HEYMAN RICHARD A.	SALE	21.48	1.27K	27.28K	134.62K
Jun 06, 2024	PATEL ANISH	SALE	20.06	1.13K	22.72K	0
May 29, 2024	LYSSIKATOS JOSEPH P	SALE	22.52	2.12K	47.81K	0
May 28, 2024	HOHL BENJAMIN	SALE	24.34	10	243.4	0
May 28, 2024	KINTZ SAMUEL	SALE	24.34	100	2.43K	0
May 16, 2024	HEYMAN RICHARD A.	SALE	23.74	1.27K	30.15K	135.89K
May 16, 2024	ORBIMED ADVISORS LLC	SALE	22.14	33.3K	737.26K	254.81K
May 16, 2024	GUPTA RISHI	SALE	22.14	33.3K	737.26K	254.81K
May 14, 2024	PATEL ANISH	SALE	25.00	1.11K	27.68K	0
May 09, 2024	PATEL ANISH	SALE	25.06	260	6.52K	0
May 06, 2024	PATEL ANISH	SALE	22.72	4.88K	110.77K	0
May 03, 2024	HOHL BENJAMIN	SALE	22.50	1K	22.5K	0
Apr 29, 2024	LYSSIKATOS JOSEPH P	SALE	18.48	1.01K	18.72K	0
Apr 29, 2024	HOHL BENJAMIN	SALE	16.97	3.25K	55.16K	0
Apr 25, 2024	KINTZ SAMUEL	SALE	16.89	12K	202.7K	0
Apr 15, 2024	HEYMAN RICHARD A.	SALE	20.68	80	1.65K	137.16K
Apr 11, 2024	PATEL ANISH	SALE	25.03	17.5K	438.1K	0
Apr 11, 2024	LYSSIKATOS JOSEPH P	SALE	25.04	30K	751.33K	0
Apr 11, 2024	HOHL BENJAMIN	SALE	25.04	10.22K	255.97K	0
Apr 11, 2024	BALLAL RAHUL D.	SALE	25.21	3.07K	77.34K	22.34K
Apr 11, 2024	COLLINS HELEN LOUISE	SALE	25.07	20K	501.48K	0
Apr 11, 2024	HEYMAN RICHARD A.	SALE	25.03	5.05K	126.28K	138
Apr 11, 2024	KINTZ SAMUEL	SALE	25.04	47.71K	1.19M	0
Apr 10, 2024	BALLAL RAHUL D.	SALE	21.01	13.6K	285.74K	22.34K
Apr 08, 2024	PATEL ANISH	SALE	19.40	544	10.55K	2.6K
Apr 04, 2024	BALLAL RAHUL D.	SALE	19.15	3.49K	66.73K	22.34K
Apr 01, 2024	BALLAL RAHUL D.	SALE	19.08	3.24K	61.76K	22.34K
Apr 01, 2024	LYSSIKATOS JOSEPH P	SALE	19.36	71	1.37K	0
Mar 27, 2024	HOHL BENJAMIN	SALE	18.72	182	3.41K	0
Mar 25, 2024	KINTZ SAMUEL	SALE	18.16	4.67K	84.84K	0
Mar 20, 2024	BALLAL RAHUL D.	SALE	19.16	13.28K	254.46K	22.34K
Mar 19, 2024	HEYMAN RICHARD A.	SALE	14.50	1.27K	18.42K	143.47K
Mar 06, 2024	PATEL ANISH	SALE	15.64	4.88K	76.24K	7.47K
Feb 29, 2024	LYSSIKATOS JOSEPH P	SALE	17.09	1.81K	30.85K	0
Feb 27, 2024	HOHL BENJAMIN	SALE	16.97	3.25K	55.16K	0
Feb 15, 2024	HEYMAN RICHARD A.	SALE	17.42	1.27K	22.12K	144.74K
Feb 14, 2024	5AM PARTNERS VI, LLC	SALE	14.90	136.64K	2.04M	635.34K
Feb 06, 2024	PATEL ANISH	SALE	15.11	4.88K	73.66K	12.35K
Jan 31, 2024	5AM PARTNERS VI, LLC	SALE	15.00	82.81K	1.24M	771.98K
Jan 30, 2024	HEYMAN RICHARD A.	SALE	16.41	1.27K	20.84K	146.01K
Jan 29, 2024	HOHL BENJAMIN	SALE	15.81	3.25K	51.39K	0
Jan 29, 2024	LYSSIKATOS JOSEPH P	SALE	15.85	12K	190.26K	0
Jan 25, 2024	KINTZ SAMUEL	SALE	15.89	9.46K	150.26K	0
Jan 22, 2024	PATEL ANISH	SALE	15.13	4.88K	73.78K	17.22K
Nov 03, 2023	LYSSIKATOS JOSEPH P		1.12	8.55K	9.57K	324K
Nov 03, 2023	KINTZ SAMUEL		1.12	8.03K	8.99K	324.52K
Sep 29, 2023	LYSSIKATOS JOSEPH P		1.12	12K	13.44K	332.55K
Sep 26, 2023	5AM PARTNERS VI, LLC	SALE	15.00	32.71K	490.67K	854.8K
Sep 25, 2023	KINTZ SAMUEL		1.12	12K	13.44K	332.55K
Aug 24, 2023	5AM PARTNERS VI, LLC	SALE	16.00	72.88K	1.17M	887.51K
May 17, 2023	ORBIMED ADVISORS LLC		4.28	2.13K	9.1K	0
May 17, 2023	GUPTA RISHI		4.28	2.13K	9.1K	0
Apr 04, 2023	KINTZ SAMUEL	AWARD	22.75	452K	10.28M	452K
Apr 04, 2023	PATEL ANISH	AWARD	22.75	206K	4.69M	206K
Apr 04, 2023	HOHL BENJAMIN	AWARD	22.75	206K	4.69M	206K
Apr 04, 2023	COLLINS HELEN LOUISE	AWARD	22.75	206K	4.69M	206K
Apr 04, 2023	LYSSIKATOS JOSEPH P	AWARD	22.75	206K	4.69M	206K
Feb 23, 2023	BALLAL RAHUL D.	AWARD	25.28	27.57K	696.89K	27.57K
Feb 23, 2023	PHILLIPS ANDREW JOHN	AWARD	25.28	27.57K	696.89K	27.57K
Feb 23, 2023	HEYMAN RICHARD A.	AWARD	25.28	34.46K	871.1K	34.46K
Feb 23, 2023	GUPTA RISHI	AWARD	25.28	27.57K	696.89K	27.57K
Feb 23, 2023	SCHWAB ANDREW J.	AWARD	25.28	27.57K	696.89K	27.57K
Feb 23, 2023	LYSSIKATOS JOSEPH P	AWARD	2.48	88.53K	219.56K	88.53K
Feb 23, 2023	PATEL ANISH	AWARD	2.48	75.62K	187.54K	75.62K
Feb 23, 2023	COMMODORE CAPITAL LP	OTHER	0.00	729.89K	-	1.45M
Feb 23, 2023	HOHL BENJAMIN	AWARD	2.48	262.12K	650.06K	262.12K
Feb 23, 2023	KINTZ SAMUEL	AWARD	2.48	404.36K	1M	404.36K
Feb 23, 2023	COLLINS HELEN LOUISE	AWARD	2.48	287.08K	711.97K	287.08K
Feb 23, 2023	RA CAPITAL MANAGEMENT, L.P.	AWARD	0.00	1.15M	-	2.12M
Feb 23, 2023	ORBIMED ADVISORS LLC	AWARD	0.00	288.11K	-	288.11K
Feb 23, 2023	DERYNCK MIKA K	AWARD	25.28	27.57K	696.89K	27.57K
Feb 23, 2023	BAUER JAKE	AWARD	25.28	27.57K	696.89K	27.57K
Feb 22, 2023	BALLAL RAHUL D.	SALE	4.66	32.86K	153.13K	87.84K
Feb 22, 2023	GRAY MICHAEL	SALE	4.67	9.86K	46.03K	27.61K
Feb 22, 2023	COMMODORE CAPITAL LP	PURCHASE	5.11	23.57K	120.49K	2.87M
Feb 21, 2023	COMMODORE CAPITAL LP	PURCHASE	5.25	8.19K	43.01K	2.85M
Jan 30, 2023	BALLAL RAHUL D.	SALE	3.91	11.31K	44.23K	120.7K
Jan 30, 2023	GRAY MICHAEL	SALE	3.92	3.6K	14.1K	37.47K
Jan 04, 2023	LEONARD BRADEN MICHAEL	SALE	4.00	1.25M	5M	1.77M
Jan 03, 2023	LEONARD BRADEN MICHAEL	SALE	4.00	1.25M	5M	1.77M

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES274.33K25

NET SHARES-274.33K25

SHARES HELD10.75M25

% NET SHARES-102.55%0%

Frequently Asked Questions