How many institutions own DSGN stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own DSGN shares is 129, representing 63.03% of the company's common stock.

Who are the major shareholders selling Design Therapeutics, Inc. stock?

D. E. SHAW & CO., INC., in the last quarter, reduced its stake in DSGN by -4.45% restricting it's holding to 373.28 thousand shares of worth nearly $2.81M. CITADEL ADVISORS LLC also lessened -34.11% of the DSGN shares from its portfolio, reducing its holding to 554.02 thousand shares of worth $4.17M. ACADIAN ASSET MANAGEMENT LLC also shunned DSGN shares holding by -1.57% last quarter which brought its holding to 617.49 thousand shares worth $4.65M.

Investors who are buying DSGN stock?

As per its latest 13F filing, HRT FINANCIAL LP increased its stake in DSGN by 100% in the last quarter. The institutional holder raised its holding to 31.9 thousand shares having worth more than $240.00K. MARINER, LLC also added 2.17% more shares of DSGN to its portfolio, raising its holding to 16.08 thousand shares of worth $121.09K. POINT72 ASSET MANAGEMENT, L.P. also increased its DSGN shares holding by 84.85% which brought its holding to 3.34 million shares worth $25.15M.

DSGN's major insiders: who are they?

The insider with the most stakes in DSGN is SR One Capital Fund I Aggregator LP , director at the company. Additionally, DSGN stock is highly held by director George Simeon and Cormorant Asset Management, LP among others.

Did an insider recently sell DSGN stock?

Company executives, directors, and other insiders own 35.98% percent of Design Therapeutics, Inc.'s stock. Within the last six months, there have been 1 transaction(s) in which DSGN insiders have sold stock, totaling 217.63K shares. Insiders that have sold shares include WILLIAM ARSANI, PRASAD DEEPA, and XU STELLA.

Which insider recently purchased DSGN stock?

There have been 0 transaction(s) during the past 6-months in which Design Therapeutics, Inc. insiders have bought stock, totalling 0 shares

How much of DSGN does insiders own?

Around 1M Design Therapeutics, Inc. shares are held by insiders, which represents about 35.98% of DSGN stock.

Who is the insider with the largest stake?

DSGN director, SR One Capital Fund I Aggregator LP holds the largest portfolio of the company's shares. DSGN shares owned by SR total nearly 6.53 million.

Which institution holds the most shares in DSGN?

D. E. SHAW & CO., INC. is the largest institutional owner in DSGN which holds 373.28 thousand shares worth $2.81M or 0.66% of the total DSGN shares outstanding followed by CITADEL ADVISORS LLC with ownership of 554.02 thousand shares representing 0.97% of the DSGN ownership. ACADIAN ASSET MANAGEMENT LLC is the third largest stakeholder with 617.49 thousand shares or 1.09% of the ownership worth more than $4.65M.

Is Design Therapeutics, Inc. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the DSGN is concerned, it is a stock which is optionable.

Is there a short position on DSGN's shares?

Number of DSGN shares short is 3.52M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding DSGN shares are there?

As of today, 56.95M shares of DSGN are outstanding.

Is there many float in DSGN stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, DSGN has 23.34M shares in float.

DSGN short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for DSGN is 22.33.

Design Therapeutics (DSGN) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares6.18

Short Percent Of Float9.34

Shares Outstanding56.95M

Shares Float23.34M

Shares Short3.52M

Short Ratio22.33

9.34%

Short % of Float

6.18%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

35.98% Percentage of Shares held by All Insiders

63.03% Percentage of Shares held by All Institutions

98.45% Percentage of Float held by Institutions

129

Number of Institutions Holding Shares

Institutional Ownership

About 63.03% of DSGN shares are held by financial institutions. D. E. SHAW & CO., INC. is the top corporate investor, holding 373.28K shares valued at $2.81M. A 0.66% stake in Design Therapeutics, Inc. is owned by the company. CITADEL ADVISORS LLC owns 554.02K shares valued at $4.17M, which translates its holding of 0.97% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Sep 30, 2025	D. E. SHAW & CO., INC.	0.66%	373.28K	2.81M	-17.37K	-4.45%
Sep 30, 2025	CITADEL ADVISORS LLC	0.97%	554.02K	4.17M	-286.77K	-34.11%
Sep 30, 2025	ACADIAN ASSET MANAGEMENT LLC	1.09%	617.49K	4.65M	-9.86K	-1.57%
Sep 30, 2025	HRT FINANCIAL LP	0.06%	31.9K	240K	31.9K	+100.00%
Sep 30, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	1.89%	1.08M	8.1M	0	0
Sep 30, 2025	MARINER, LLC	0.03%	16.08K	121.09K	341	+2.17%
Sep 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	0.03%	16.31K	123K	0	0
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0.03%	18.32K	137.93K	-1.97K	-9.70%
Sep 30, 2025	VELAN CAPITAL INVESTMENT MANAGEMENT LP	0.04%	20K	150.6K	0	0
Sep 30, 2025	ALMITAS CAPITAL LLC	2.69%	1.53M	11.52M	0	0
Sep 30, 2025	BAKER BROS. ADVISORS LP	3.01%	1.71M	12.9M	0	0
Sep 30, 2025	TANG CAPITAL MANAGEMENT LLC	3.13%	1.78M	13.41M	0	0
Sep 30, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	3.44%	1.95M	14.71M	0	0
Sep 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	5.88%	3.34M	25.15M	1.53M	+84.85%
Sep 30, 2025	LOGOS GLOBAL MANAGEMENT LP	6.43%	3.66M	27.52M	-562.63K	-13.34%
Sep 30, 2025	PALUMBO WEALTH MANAGEMENT LLC	0.09%	52.08K	392.17K	-8.47K	-13.99%
Sep 30, 2025	TWO SIGMA INVESTMENTS, LP	0.1%	59.24K	446.06K	-30.07K	-33.67%
Sep 30, 2025	LYNX1 CAPITAL MANAGEMENT LP	0.12%	65.95K	496.63K	0	0
Sep 30, 2025	MILLENNIUM MANAGEMENT LLC	0.12%	68.82K	518.24K	68.82K	+100.00%
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.15%	87.48K	658.69K	-7.13K	-7.53%
Sep 30, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.04%	21.92K	165.04K	21.92K	+100.00%
Sep 30, 2025	STATE OF WISCONSIN INVESTMENT BOARD	0.05%	27.06K	203.78K	-1.6K	-5.58%
Sep 30, 2025	KENNEDY CAPITAL MANAGEMENT LLC	0.05%	29.41K	221.47K	14.4K	+95.94%
Sep 30, 2025	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.06%	34.98K	263.41K	23.58K	+206.81%
Sep 30, 2025	TWO SIGMA ADVISERS, LP	0.07%	40.5K	304.97K	-68K	-62.67%
Sep 30, 2025	DLD ASSET MANAGEMENT, LP	0.09%	50K	376.5K	50K	+100.00%
Sep 30, 2025	AMERICAN CENTURY COMPANIES INC	0.09%	50.85K	382.92K	4.47K	+9.63%
Sep 30, 2025	PRUDENTIAL FINANCIAL INC	0.08%	44.83K	337.53K	-13.1K	-22.62%
Sep 30, 2025	ALLIANCEBERNSTEIN L.P.	0.08%	46.12K	347.28K	1.09K	+2.42%
Sep 30, 2025	RHUMBLINE ADVISERS	0.08%	46.33K	348.89K	-1.98K	-4.10%
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.48%	274.3K	2.07M	6.5K	+2.43%
Sep 30, 2025	RA CAPITAL MANAGEMENT, L.P.	0.84%	475.7K	3.58M	475.7K	+100.00%
Sep 30, 2025	VANGUARD GROUP INC	2.54%	1.44M	10.87M	-27.87K	-1.89%
Sep 30, 2025	BLACKROCK, INC.	3.6%	2.04M	15.39M	-351.36K	-14.67%
Sep 30, 2025	SR ONE CAPITAL MANAGEMENT, LP	11.48%	6.53M	49.14M	0	0
Sep 30, 2025	PHYSICIAN WEALTH ADVISORS, INC.	0%	268	2.02K	0	0
Sep 30, 2025	OPTIVER HOLDING B.V.	0%	328	2.47K	328	+100.00%
Sep 30, 2025	FARTHER FINANCE ADVISORS, LLC	0%	385	2.9K	366	+1,926.32%
Sep 30, 2025	GAMMA INVESTING LLC	0%	443	3.34K	443	+100.00%
Sep 30, 2025	PRIVATE WEALTH MANAGEMENT GROUP, LLC	0%	558	4.2K	0	0
Sep 30, 2025	CLEARSTEAD ADVISORS, LLC	0%	610	4.59K	0	0
Sep 30, 2025	AMALGAMATED BANK	0%	1.18K	9K	0	0
Sep 30, 2025	GF FUND MANAGEMENT CO. LTD.	0%	1.21K	9.13K	-236	-16.29%
Sep 30, 2025	CITIGROUP INC	0%	1.59K	11.97K	-12.06K	-88.35%
Sep 30, 2025	BARCLAYS PLC	0.16%	88.18K	663.97K	-21.36K	-19.50%
Sep 30, 2025	JANE STREET GROUP, LLC	0.21%	117.83K	887.28K	86.75K	+279.14%
Sep 30, 2025	NUVEEN, LLC	0.23%	133.03K	1M	0	0
Sep 30, 2025	MORGAN STANLEY	0.31%	175.99K	1.33M	-37.56K	-17.59%
Sep 30, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.33%	188.2K	1.42M	0	0
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.22%	695.61K	5.24M	-98.4K	-12.39%
Sep 30, 2025	STERLING CAPITAL MANAGEMENT LLC	0%	1.65K	12.41K	807	+95.96%
Sep 30, 2025	PNC FINANCIAL SERVICES GROUP, INC.	0%	1.82K	13.73K	152	+9.10%
Sep 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0%	2.03K	15.26K	0	0
Sep 30, 2025	LEGAL & GENERAL GROUP PLC	0%	2.08K	15.66K	-1K	-32.52%
Sep 30, 2025	MIRAE ASSET GLOBAL INVESTMENTS CO., LTD.	0%	2.2K	16.58K	9	+0.41%
Sep 30, 2025	AMERITAS INVESTMENT PARTNERS, INC.	0%	2.57K	19.35K	0	0
Sep 30, 2025	CAZ INVESTMENTS LP	0.01%	5K	37.65K	-2.5K	-33.33%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.01%	5.13K	38.65K	1.31K	+34.27%
Sep 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0.01%	6.38K	48.02K	2.62K	+69.65%
Sep 30, 2025	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0.01%	6.6K	49.68K	0	0
Sep 30, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.02%	10.32K	77.71K	10.32K	+100.00%
Sep 30, 2025	NISA INVESTMENT ADVISORS, LLC	0.02%	11.82K	89.04K	0	0
Sep 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.02%	14.16K	106.59K	-5.51K	-28.03%
Sep 30, 2025	INVESCO LTD.	0.03%	14.59K	109.85K	225	+1.57%
Sep 30, 2025	NORTHERN TRUST CORP	0.52%	296.53K	2.23M	-65.99K	-18.20%
Sep 30, 2025	BIOIMPACT CAPITAL LLC	0.98%	555.19K	4.18M	0	0
Sep 30, 2025	FMR LLC	1.3%	740.85K	5.58M	-210.35K	-22.11%
Sep 30, 2025	STRS OHIO	0.04%	22.6K	170.18K	0	0
Sep 30, 2025	UBS GROUP AG	0.04%	22.69K	170.88K	-4.65K	-17.00%
Sep 30, 2025	MASSMUTUAL TRUST CO FSB/ADV	0%	239	1.8K	0	0
Sep 30, 2025	EVERSOURCE WEALTH ADVISORS, LLC	0%	235	1.77K	0	0
Sep 30, 2025	CWM, LLC	0%	222	2K	-49	-18.08%
Sep 30, 2025	JPMORGAN CHASE & CO	0.04%	23.22K	174.85K	4.9K	+26.72%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.04%	23.91K	180.02K	-718	-2.92%
Sep 30, 2025	WOODLINE PARTNERS LP	1.08%	612.71K	4.61M	-164.83K	-21.20%
Sep 30, 2025	STATE STREET CORP	1.12%	634.4K	4.78M	-84.82K	-11.79%
Sep 30, 2025	KYNAM CAPITAL MANAGEMENT, LP	1.81%	1.03M	7.75M	0	0
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.44%	247.93K	1.87M	-3.02K	-1.20%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	0.46%	261.45K	1.97M	21.99K	+9.18%
Sep 30, 2025	DIMENSIONAL FUND ADVISORS LP	0.49%	279.82K	2.11M	-33.55K	-10.71%
Jun 30, 2025	VANGUARD GROUP INC	2.59%	1.47M	4.96M	44.11K	+3.09%
Jun 30, 2025	ALMITAS CAPITAL LLC	2.69%	1.53M	5.16M	77.54K	+5.34%
Jun 30, 2025	BAKER BROS. ADVISORS LP	3.01%	1.71M	5.77M	-30.84K	-1.77%
Jun 30, 2025	BARCLAYS PLC	0.19%	109.54K	368K	25.53K	+30.39%
Jun 30, 2025		0.23%	133.03K	448.3K	-14.2K	-9.64%
Jun 30, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.33%	188.2K	634.23K	74.4K	+65.38%
Jun 30, 2025	SR ONE CAPITAL MANAGEMENT, LP	11.48%	6.53M	21.99M	0	0
Jun 30, 2025	LOGOS GLOBAL MANAGEMENT LP	7.42%	4.22M	14.21M	0	0
Jun 30, 2025	BLACKROCK, INC.	4.21%	2.4M	8.07M	-84.22K	-3.40%
Jun 30, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	3.44%	1.95M	6.58M	0	0
Jun 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	3.18%	1.81M	6.09M	-10.64K	-0.59%
Jun 30, 2025	CITADEL ADVISORS LLC	1.48%	840.79K	2.83B	-122.67K	-12.73%
Jun 30, 2025	BIOIMPACT CAPITAL LLC	0.98%	555.19K	1.87M	-7.76K	-1.38%
Jun 30, 2025	D. E. SHAW & CO., INC.	0.69%	390.65K	1.32B	-4.6K	-1.16%
Jun 30, 2025	NORTHERN TRUST CORP	0.64%	362.52K	1.22M	-11.14K	-2.98%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.42%	239.46K	806.98M	-26.56K	-9.98%
Jun 30, 2025	MORGAN STANLEY	0.38%	213.55K	719.66M	-34.33K	-13.85%
Jun 30, 2025	AMERICAN CENTURY COMPANIES INC	0.08%	46.39K	156.32K	1.97K	+4.44%
Jun 30, 2025	ALLIANCEBERNSTEIN L.P.	0.08%	45.03K	151.75M	2.94K	+6.99%
Jun 30, 2025	AQR CAPITAL MANAGEMENT LLC	0.05%	28.73K	96.81M	-3.01K	-9.50%
Jun 30, 2025	CI PRIVATE WEALTH, LLC	0.05%	26.97K	90.87K	0	0
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0.04%	24.63K	82.99K	2.46K	+11.09%
Jun 30, 2025	STRS OHIO	0.04%	22.6K	76.16K	0	0
Jun 30, 2025	TANG CAPITAL MANAGEMENT LLC	3.13%	1.78M	6M	100K	+5.95%
Jun 30, 2025	DIMENSIONAL FUND ADVISORS LP	0.55%	313.36K	1.06M	24.76K	+8.58%
Jun 30, 2025	STATE STREET CORP	1.26%	719.21K	2.42M	5.14K	+0.72%
Jun 30, 2025	WOODLINE PARTNERS LP	1.37%	777.54K	2.62M	131.84K	+20.42%
Jun 30, 2025	ACADIAN ASSET MANAGEMENT LLC	1.1%	627.35K	2.11M	-3.61K	-0.57%
Jun 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.03%	19.67K	66.28K	-882	-4.29%
Jun 30, 2025	JPMORGAN CHASE & CO	0.03%	18.33K	61.76K	-952	-4.94%
Jun 30, 2025	MIRAE ASSET GLOBAL ETFS HOLDINGS LTD.	0.03%	17.96K	60.52K	-780	-4.16%
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	0.03%	16.31K	55K	3.25K	+24.83%
Jun 30, 2025	MARINER, LLC	0.03%	15.74K	53.04K	269	+1.74%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.4%	794.01K	2.68M	18.51K	+2.39%
Jun 30, 2025	VELAN CAPITAL INVESTMENT MANAGEMENT LP	0.04%	20K	67.4K	6K	+42.86%
Jun 30, 2025	WELLS FARGO & COMPANY/MN	0.04%	20.28K	68.36K	1.44K	+7.63%
Jun 30, 2025	UBS GROUP AG	0.05%	27.34K	92.14K	-5.48K	-16.69%
Jun 30, 2025	FMR LLC	1.67%	951.2K	3.21M	3.15K	+0.33%
Jun 30, 2025	DEUTSCHE BANK AG\	0.05%	28.09K	94.68K	-35	-0.12%
Jun 30, 2025	STATE OF WISCONSIN INVESTMENT BOARD	0.05%	28.66K	96.59K	6.7K	+30.51%
Jun 30, 2025	JANE STREET GROUP, LLC	0.05%	31.08K	104.74K	12.95K	+71.47%
Jun 30, 2025	ASSENAGON ASSET MANAGEMENT S.A.	0.05%	31.13K	104.89K	-5.79K	-15.69%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.07%	38.17K	128.63K	-5.05K	-11.69%
Jun 30, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	0.07%	42.41K	142.92K	42.41K	+100.00%
Jun 30, 2025	RHUMBLINE ADVISERS	0.09%	48.32K	162.82K	1.95K	+4.20%
Jun 30, 2025	PRUDENTIAL FINANCIAL INC	0.1%	57.93K	195.21K	1.52K	+2.69%
Jun 30, 2025	GSA CAPITAL PARTNERS LLP	0.11%	59.98K	202K	-12.17K	-16.87%
Jun 30, 2025	PALUMBO WEALTH MANAGEMENT LLC	0.11%	60.56K	204.07K	2.28K	+3.91%
Jun 30, 2025	LYNX1 CAPITAL MANAGEMENT LP	0.12%	65.95K	222.27K	0	0
Jun 30, 2025	TWO SIGMA INVESTMENTS, LP	0.16%	89.31K	300.98K	-39.44K	-30.63%
Jun 30, 2025	BANK OF NEW YORK MELLON CORP	0.17%	94.6K	318.81K	-745	-0.78%
Jun 30, 2025	TWO SIGMA ADVISERS, LP	0.19%	108.5K	365.65K	-38.2K	-26.04%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.44%	250.95K	845.7K	-7.43K	-2.87%
Jun 30, 2025	NUVEEN, LLC	0.23%	133.03K	448.3K	-14.2K	-9.64%
Jun 30, 2025	KYNAM CAPITAL MANAGEMENT, LP	1.81%	1.03M	3.47M	125.56K	+13.89%
Jun 30, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	1.89%	1.08M	3.63M	162.84K	+17.83%
Jun 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.47%	267.8K	902.49K	2.8K	+1.06%
Mar 31, 2025	BANK OF NEW YORK MELLON CORP	0.17%	95.35K	368.04K	0	0
Mar 31, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.2%	113.8K	439.27K	-14.6K	-11.37%
Mar 31, 2025	RHUMBLINE ADVISERS	0.08%	46.37K	178.98K	-6.56K	-12.40%
Mar 31, 2025	UBS GROUP AG	0.06%	32.82K	126.68K	-33.77K	-50.71%
Mar 31, 2025	CI PRIVATE WEALTH, LLC	0.05%	26.97K	104.09K	0	0
Mar 31, 2025	CITIGROUP INC	0.04%	22.88K	88.31K	-1.6K	-6.52%
Mar 31, 2025	STRS OHIO	0.04%	22.6K	87.24K	-10K	-30.67%
Mar 31, 2025	BAKER BROS. ADVISORS LP	3.07%	1.74M	6.73M	0	0
Mar 31, 2025	VANGUARD GROUP INC	2.52%	1.43M	5.51M	-3.28K	-0.23%
Mar 31, 2025	CITADEL ADVISORS LLC	1.7%	963.46K	3.72M	4.67K	+0.49%
Mar 31, 2025	PALUMBO WEALTH MANAGEMENT LLC	0.1%	58.28K	224.95K	3.58K	+6.55%
Mar 31, 2025	PRUDENTIAL FINANCIAL INC	0.1%	56.41K	217.72K	90	+0.16%
Mar 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.09%	52.87K	204.09K	12.58K	+31.23%
Mar 31, 2025	AMERICAN CENTURY COMPANIES INC	0.08%	44.42K	171.44K	5.3K	+13.55%
Mar 31, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	1.61%	913.4K	3.53M	137.32K	+17.69%
Mar 31, 2025	KYNAM CAPITAL MANAGEMENT, LP	1.59%	904.02K	3.49M	904.02K	+100.00%
Mar 31, 2025	SR ONE CAPITAL MANAGEMENT, LP	11.5%	6.53M	25.19M	0	0
Mar 31, 2025	LOGOS GLOBAL MANAGEMENT LP	7.43%	4.22M	16.28M	0	0
Mar 31, 2025	BLACKROCK, INC.	4.37%	2.48M	9.57M	-99.64K	-3.86%
Mar 31, 2025	POINT72 ASSET MANAGEMENT, L.P.	3.2%	1.82M	7.02M	-38.89K	-2.09%
Mar 31, 2025	BIOIMPACT CAPITAL LLC	0.99%	562.94K	2.17M	3.4K	+0.61%
Mar 31, 2025	D. E. SHAW & CO., INC.	0.7%	395.25K	1.53M	-117.08K	-22.85%
Mar 31, 2025	NORTHERN TRUST CORP	0.66%	373.65K	1.44M	-14.47K	-3.73%
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	0.16%	87.99K	339.63K	87.99K	+100.00%
Mar 31, 2025	BARCLAYS PLC	0.15%	84.01K	324K	-19.57K	-18.89%
Mar 31, 2025	FMR LLC	1.67%	948.05K	3.66M	-3.83K	-0.40%
Mar 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.08%	43.22K	166.84K	5.91K	+15.84%
Mar 31, 2025	ALLIANCEBERNSTEIN L.P.	0.07%	42.09K	162.47K	0	0
Mar 31, 2025	ASSENAGON ASSET MANAGEMENT S.A.	0.07%	36.92K	142.5K	-19.7K	-34.80%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.37%	775.5K	2.99M	13.86K	+1.82%
Mar 31, 2025	DIMENSIONAL FUND ADVISORS LP	0.51%	288.6K	1.11M	73.34K	+34.07%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.47%	266.02K	1.03M	-31.11K	-10.47%
Mar 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0.47%	265K	1.02M	11.5K	+4.54%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.46%	258.38K	997.33K	-6.3K	-2.38%
Mar 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.25%	141.52K	546.26K	141.52K	+100.00%
Mar 31, 2025		0.26%	147.23K	568.3K	147.23K	+100.00%
Mar 31, 2025	TWO SIGMA ADVISERS, LP	0.26%	146.7K	566.26K	-87.2K	-37.28%
Mar 31, 2025	TWO SIGMA INVESTMENTS, LP	0.23%	128.75K	496.96K	-75.18K	-36.87%
Mar 31, 2025	GSA CAPITAL PARTNERS LLP	0.13%	72.15K	278K	-46.18K	-39.03%
Mar 31, 2025	LYNX1 CAPITAL MANAGEMENT LP	0.12%	65.95K	254.58K	65.95K	+100.00%
Mar 31, 2025	DEUTSCHE BANK AG\	0.05%	28.13K	108.58K	35	+0.12%
Mar 31, 2025	STATE STREET CORP	1.26%	714.07K	2.76M	-9.25K	-1.28%
Mar 31, 2025	WOODLINE PARTNERS LP	1.14%	645.69K	2.49M	645.69K	+100.00%
Mar 31, 2025	TANG CAPITAL MANAGEMENT LLC	2.96%	1.68M	6.49M	200K	+13.50%
Mar 31, 2025	ALMITAS CAPITAL LLC	2.56%	1.45M	5.61M	129.23K	+9.76%
Mar 31, 2025	ACADIAN ASSET MANAGEMENT LLC	1.11%	630.95K	2.43M	63.35K	+11.16%
Mar 31, 2025	MORGAN STANLEY	0.44%	247.88K	956.81K	-98.31K	-28.40%
Mar 31, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	3.44%	1.95M	7.54M	0	0
Mar 31, 2025	AQR CAPITAL MANAGEMENT LLC	0.06%	31.74K	122.52K	1.89K	+6.31%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0.04%	22.17K	85.56K	-12.99K	-36.96%
Mar 31, 2024	GW&K INVESTMENT MANAGEMENT, LLC	0%	674.04K	61.7M	-13.37K	-1.94%
Mar 31, 2024	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	0%	2.08M	190.08M	-238.03K	-10.28%
Mar 31, 2024	PRIMECAP MANAGEMENT CO/CA/	0%	2.29M	209.58M	-53.2K	-2.27%
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	0.01%	7.6M	695.86M	278.8K	+3.81%
Mar 31, 2024	PREMIER FUND MANAGERS LTD	0%	451.12K	41.52M	-1.86K	-0.41%
Mar 31, 2024	ARTISAN PARTNERS LIMITED PARTNERSHIP	0%	461.04K	42.19M	0	0
Mar 31, 2024	WASATCH ADVISORS LP	0%	469.17K	42.93M	-21.08K	-4.30%
Mar 31, 2024	RIVERBRIDGE PARTNERS LLC	0%	976.61K	89.39M	261.69K	+36.60%
Mar 31, 2024	MASSACHUSETTS FINANCIAL SERVICES CO /MA/	0%	487.86K	44.65M	4.86K	+1.01%
Mar 31, 2024	WESTFIELD CAPITAL MANAGEMENT CO LP	0%	518.74K	47.48M	518.74K	+100.00%
Mar 31, 2024	BANK OF NOVA SCOTIA	0%	533.26K	48.78M	25.77K	+5.08%
Mar 31, 2024	ALLSPRING GLOBAL INVESTMENTS HOLDINGS, LLC	0%	546.43K	50.01M	118.15K	+27.59%
Mar 31, 2024	BAIRD FINANCIAL GROUP, INC.	0%	566.6K	51.86M	-3.69K	-0.65%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0%	580.94K	53.16M	17.79K	+3.16%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0%	605.03K	55.38M	95.34K	+18.71%
Mar 31, 2024	JANUS HENDERSON GROUP PLC	0%	688.77K	63.06M	-25.44K	-3.56%
Mar 31, 2024	CREDIT SUISSE AG/	0%	695.49K	63.66M	-3.63K	-0.52%
Mar 31, 2024	FIERA CAPITAL CORP	0%	2.48M	226.76M	55.52K	+2.29%
Mar 31, 2024	DURABLE CAPITAL PARTNERS LP	0.01%	3.63M	332.7M	-219.04K	-5.68%
Mar 31, 2024	RUSSELL INVESTMENTS GROUP, LTD.	0%	262.62K	24.04M	8.72K	+3.44%
Mar 31, 2024	ZENO EQUITY PARTNERS LLP	0%	264.58K	24.22M	132.43K	+100.21%
Mar 31, 2024	STEPHENS INVESTMENT MANAGEMENT GROUP LLC	0%	265.35K	24.29M	-4.75K	-1.76%
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	0%	266.79K	24.42M	78.59K	+41.76%
Mar 31, 2024	MORGAN STANLEY	0%	273.36K	25.02M	-52.73K	-16.17%
Mar 31, 2024	PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO	0%	280.23K	25.65M	20.23K	+7.78%
Mar 31, 2024	JENNISON ASSOCIATES LLC	0%	315.71K	28.9M	-14.86K	-4.49%
Mar 31, 2024	SUMMIT CREEK ADVISORS LLC	0%	315.99K	28.92M	2.04K	+0.65%
Mar 31, 2024	GRANITE INVESTMENT PARTNERS, LLC	0%	332.91K	30.47M	-12.52K	-3.62%
Mar 31, 2024	BLAIR WILLIAM & CO/IL	0%	344.49K	31.53M	15.55K	+4.73%
Mar 31, 2024	BLACKROCK INC.	0%	352.54K	32.27M	-1.07K	-0.30%
Mar 31, 2024	SEGALL BRYANT & HAMILL, LLC	0%	363.34K	33.26M	2.15K	+0.60%
Mar 31, 2024	NEUBERGER BERMAN GROUP LLC	0%	379.15K	34.7M	-73.11K	-16.17%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	0%	406.74K	37.37M	15.71K	+4.02%
Mar 31, 2024	RENAISSANCE TECHNOLOGIES LLC	0%	430.1K	39.37M	35.3K	+8.94%
Mar 31, 2024	CLEARBRIDGE INVESTMENTS, LLC	0%	432.93K	39.63M	-4.47K	-1.02%
Mar 31, 2024	ROYAL BANK OF CANADA	0%	734.16K	67.2M	52.56K	+7.71%
Mar 31, 2024	CONESTOGA CAPITAL ADVISORS, LLC	0.01%	3.05M	279.12M	23.29K	+0.77%
Mar 31, 2024	VANGUARD GROUP INC	0.01%	3.14M	287.19M	40.9K	+1.32%
Mar 31, 2024	BESSEMER GROUP INC	0%	169.54K	15.52M	11.03K	+6.96%
Mar 31, 2024	SEI INVESTMENTS CO	0%	187.28K	17.14B	68.1K	+57.15%
Mar 31, 2024	NORTHERN TRUST CORP	0%	209.78K	19.2M	17.02K	+8.83%
Mar 31, 2024	ADDENDA CAPITAL INC.	0%	226.19K	28.02M	-10.19K	-4.31%
Mar 31, 2024	MACQUARIE GROUP LTD	0%	234.08K	21.43M	217.7K	+1,329.05%
Mar 31, 2024	1832 ASSET MANAGEMENT L.P.	0%	234.19K	21.43M	-8.45K	-3.48%
Mar 31, 2024	HERALD INVESTMENT MANAGEMENT LTD	0%	240K	21.95M	-15K	-5.88%
Mar 31, 2024	PRINCIPAL FINANCIAL GROUP INC	0%	243.8K	22.32M	-37.41K	-13.30%
Mar 31, 2024	THRIVENT FINANCIAL FOR LUTHERANS	0%	249.13K	22.8M	3.84K	+1.56%
Mar 31, 2024	CHEVY CHASE TRUST HOLDINGS, LLC	0%	252.15K	23.08M	-4K	-1.56%
Mar 31, 2024	SWISS NATIONAL BANK	0%	257.12K	23.51M	-19.6K	-7.08%
Mar 31, 2024	JARISLOWSKY, FRASER LTD	0.01%	3.33M	304.81M	-1.01M	-23.21%
Mar 31, 2024	LEGAL & GENERAL GROUP PLC	0%	484.05K	44.3M	-26.32K	-5.16%
Mar 31, 2024	AMERIPRISE FINANCIAL INC	0%	475.11K	49.85M	-134.47K	-22.06%
Mar 31, 2024	LORD, ABBETT & CO. LLC	0%	764.65K	69.99M	86.55K	+12.76%
Mar 31, 2024	TD ASSET MANAGEMENT INC	0%	820.43K	75.11M	47.95K	+6.21%
Mar 31, 2024	FRANKLIN RESOURCES INC	0%	1.23M	112.5M	404.47K	+49.04%
Mar 31, 2024	ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	0%	1.25M	113.93M	-128.64K	-9.36%
Mar 31, 2024	GENEVA CAPITAL MANAGEMENT LLC	0%	1.46M	133.49M	-9.94K	-0.68%
Mar 31, 2024	BANK OF MONTREAL /CAN/	0%	1.52M	141.97M	18.68K	+1.24%
Mar 31, 2024	INVESCO LTD.	0%	1.53M	140.08M	-6.9K	-0.45%
Mar 31, 2024	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0%	1.87M	170.69M	143.37K	+8.33%
Mar 31, 2024	MACKENZIE FINANCIAL CORP	0%	2.04M	186.94M	128.69K	+6.72%
Dec 31, 2023	DURABLE CAPITAL PARTNERS LP	6.88%	3.85M	323.96M	323.07K	+9.15%
Dec 31, 2023	ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	2.45%	1.37M	115.42M	598.67K	+77.24%
Dec 31, 2023	GENEVA CAPITAL MANAGEMENT LLC	2.62%	1.47M	123.43M	6.5K	+0.44%
Dec 31, 2023	BANK OF MONTREAL /CAN/	2.69%	1.51M	127.74M	283.07K	+23.16%
Dec 31, 2023	INVESCO LTD.	2.75%	1.54M	129.23M	18.62K	+1.23%
Dec 31, 2023	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	3.08%	1.72M	144.68M	177.55K	+11.50%
Dec 31, 2023	MACKENZIE FINANCIAL CORP	3.42%	1.91M	160.91M	154.11K	+8.76%
Dec 31, 2023	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	4.13%	2.31M	194.57M	51.39K	+2.27%
Dec 31, 2023	PRIMECAP MANAGEMENT CO/CA/	4.18%	2.34M	196.95M	-221.5K	-8.64%
Dec 31, 2023	FIERA CAPITAL CORP	4.33%	2.42M	204.17M	206.19K	+9.31%
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	13.08%	7.32M	615.64M	-1.5M	-16.96%
Dec 31, 2023	CONESTOGA CAPITAL ADVISORS, LLC	5.41%	3.03M	254.38M	5.27K	+0.17%
Dec 31, 2023	JARISLOWSKY, FRASER LTD	7.74%	4.34M	366.03M	-119.22K	-2.68%
Dec 31, 2023	STEPHENS INVESTMENT MANAGEMENT GROUP LLC	0.48%	270.09K	22.7M	17.17K	+6.79%
Dec 31, 2023	MAN GROUP PLC	0.49%	273.15K	23.06M	-31.3K	-10.28%
Dec 31, 2023	SWISS NATIONAL BANK	0.49%	276.72K	23.29M	-8K	-2.81%
Dec 31, 2023	PRINCIPAL FINANCIAL GROUP INC	0.5%	281.21K	23.74M	-3.01K	-1.06%
Dec 31, 2023	SUMMIT CREEK ADVISORS LLC	0.56%	313.95K	26.39M	-24.5K	-7.24%
Dec 31, 2023	TWO SIGMA INVESTMENTS, LP	0.58%	322.14K	27.08M	137.14K	+74.13%
Dec 31, 2023	MORGAN STANLEY	0.58%	326.09K	27.41M	-106.64K	-24.64%
Dec 31, 2023	BLAIR WILLIAM & CO/IL	0.59%	328.94K	27.65M	11.05K	+3.48%
Dec 31, 2023	JENNISON ASSOCIATES LLC	0.59%	330.57K	27.79M	-2.93K	-0.88%
Dec 31, 2023	GRANITE INVESTMENT PARTNERS, LLC	0.62%	345.42K	29.04M	-14.77K	-4.10%
Dec 31, 2023	BLACKROCK INC.	0.63%	353.61K	29.72M	32.03K	+9.96%
Dec 31, 2023	SEGALL BRYANT & HAMILL, LLC	0.65%	361.19K	30.36M	84.45K	+30.51%
Dec 31, 2023	VANGUARD GROUP INC	5.53%	3.1M	260.31M	31.08K	+1.01%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	0.7%	391.03K	33.09M	15.95K	+4.25%
Dec 31, 2023	RENAISSANCE TECHNOLOGIES LLC	0.71%	394.8K	33.2M	67.1K	+20.48%
Dec 31, 2023	ALLSPRING GLOBAL INVESTMENTS HOLDINGS, LLC	0.76%	428.28K	36M	356.56K	+497.16%
Dec 31, 2023	CLEARBRIDGE INVESTMENTS, LLC	0.78%	437.39K	36.77M	437.39K	+100.00%
Dec 31, 2023	NEUBERGER BERMAN GROUP LLC	0.81%	452.26K	38.02M	25.19K	+5.90%
Dec 31, 2023	PREMIER FUND MANAGERS LTD	0.81%	452.98K	37.89M	0	0
Dec 31, 2023	ARTISAN PARTNERS LIMITED PARTNERSHIP	0.82%	461.04K	38.74M	-45.1K	-8.91%
Dec 31, 2023	MASSACHUSETTS FINANCIAL SERVICES CO /MA/	0.86%	483K	40.6M	74.33K	+18.19%
Dec 31, 2023	WASATCH ADVISORS LP	0.88%	490.25K	41.19M	-52.72K	-9.71%
Dec 31, 2023	BANK OF NOVA SCOTIA	0.91%	507.49K	42.64M	71.23K	+16.33%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.91%	509.68K	42.84M	99.27K	+24.19%
Dec 31, 2023	LEGAL & GENERAL GROUP PLC	0.91%	510.37K	43.09M	96.63K	+23.35%
Dec 31, 2023	MANUFACTURERS LIFE INSURANCE COMPANY, THE	1.01%	563.15K	47.39M	33.17K	+6.26%
Dec 31, 2023	BAIRD FINANCIAL GROUP, INC.	1.02%	570.29K	47.94M	15.41K	+2.78%
Dec 31, 2023	AMERIPRISE FINANCIAL INC	1.09%	609.58K	60.41M	-126.04K	-17.13%
Dec 31, 2023	LORD, ABBETT & CO. LLC	1.21%	678.1K	57M	-3.57K	-0.52%
Dec 31, 2023	ROYAL BANK OF CANADA	1.22%	681.6K	57.3M	25.07K	+3.82%
Dec 31, 2023	GW&K INVESTMENT MANAGEMENT, LLC	1.23%	687.41K	57.78M	-38.31K	-5.28%
Dec 31, 2023	CREDIT SUISSE AG/	1.25%	699.12K	58.77M	86.72K	+14.16%
Dec 31, 2023	JANUS HENDERSON GROUP PLC	1.28%	714.2K	60.3M	2.33K	+0.33%
Dec 31, 2023	RIVERBRIDGE PARTNERS LLC	1.28%	714.93K	60.1M	-8.93K	-1.23%
Dec 31, 2023	TD ASSET MANAGEMENT INC	1.38%	772.48K	65.2M	73.41K	+10.50%
Dec 31, 2023	FRANKLIN RESOURCES INC	1.47%	824.69K	69.32M	-442.12K	-34.90%
Dec 31, 2023	NORGES BANK	1.97%	1.1M	92.57M	1.1M	+100.00%

Insiders

Among the DSGN insiders holding of 35.98% of the stake in company, SR ONE CAPITAL FUND I AGGREGATOR LP, director, holds the largest shares of 6.53M. GEORGE SIMEON, director, is the second largest DSGN insider with ownership of 6.53M shares. CORMORANT ASSET MANAGEMENT, LP, , stands third with possession of 5.11M shares of that stake.

Insiders	Designation	Shares Held
SR ONE CAPITAL FUND I AGGREGATOR LP	director	6.53M
GEORGE SIMEON	director	6.53M
CORMORANT ASSET MANAGEMENT, LP		5.11M
XU STELLA		4.16M
WILLIAM ARSANI	director	1M
LAPPE RODNEY W	director	133.02K
SIFFERT JOAO MD	President and CEO	132.62K
SCHMID JOHN P.	director	26.97K
SHAH PRATIK	Executive Chairperson	25K
PRASAD DEEPA	director	20K
THACKER JUSTIN	Vice President, Finance	17.5K
JEFFRIES SEAN	Chief Operating Officer	3.05K
BERGER HEATHER A.	director	1.3K

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Aug 13, 2025	WILLIAM ARSANI	SALE	5.25	217.63K	1.14M	1M
Dec 18, 2024	PRASAD DEEPA	SALE	6.27	3.81K	23.86K	20K
Aug 09, 2024	WILLIAM ARSANI	SALE	4.25	814.87K	3.46M	0
Mar 25, 2024	BERGER HEATHER A.	PURCHASE	3.74	1.3K	4.87K	1.3K
Mar 25, 2024	SCHMID JOHN P.	PURCHASE	3.74	17.81K	66.61K	26.97K
Mar 22, 2024	SCHMID JOHN P.	PURCHASE	3.62	9.16K	33.13K	9.16K
Sep 29, 2023	LAPPE RODNEY W	PURCHASE	2.35	21K	49.29K	133.02K
Aug 29, 2023	WILLIAM ARSANI	PURCHASE	2.44	1.96M	4.78M	3M
Aug 29, 2023	PRASAD DEEPA	PURCHASE	2.31	12K	27.67K	23.81K
Aug 28, 2023	WILLIAM ARSANI	PURCHASE	2.15	275K	591.25K	1.04M
Dec 20, 2022	GEORGE SIMEON	PURCHASE	8.14	40K	325.43K	6.53M
Dec 20, 2022	SIFFERT JOAO MD	PURCHASE	8.38	6.3K	52.76K	132.62K
Dec 20, 2022	SR ONE CAPITAL FUND I AGGREGATOR LP	PURCHASE	8.14	40K	325.43K	6.53M
Dec 19, 2022	GEORGE SIMEON	PURCHASE	8.63	360K	3.11M	6.49M
Dec 19, 2022	SIFFERT JOAO MD	PURCHASE	8.47	1.15K	9.74K	126.32K
Dec 19, 2022	SR ONE CAPITAL FUND I AGGREGATOR LP	PURCHASE	8.63	360K	3.11M	6.49M
Dec 16, 2022	GEORGE SIMEON	PURCHASE	8.28	500K	4.14M	6.13M
Dec 16, 2022	SR ONE CAPITAL FUND I AGGREGATOR LP	PURCHASE	8.28	500K	4.14M	6.13M
Dec 09, 2022	LAPPE RODNEY W	PURCHASE	7.96	15K	119.43K	112.02K
Mar 21, 2022	WILLIAM ARSANI	PURCHASE	18.99	25K	474.68K	2.8M
Mar 18, 2022	XU STELLA	SALE	20.34	13.2K	268.49K	4.16M
Aug 31, 2021	WILLIAM ARSANI	PURCHASE	15.45	40K	618K	2.77M
Mar 30, 2021	GEORGE SIMEON	PURCHASE	20.00	250K	5M	5.63M
Mar 30, 2021	LAPPE RODNEY W	PURCHASE	20.00	5K	100K	97.02K
Mar 30, 2021	SHAH PRATIK	PURCHASE	20.00	25K	500K	25K
Mar 30, 2021	THACKER JUSTIN	PURCHASE	20.00	17.5K	350K	17.5K
Mar 30, 2021	XU STELLA	PURCHASE	20.00	10K	200K	4.73M
Mar 30, 2021	CORMORANT ASSET MANAGEMENT, LP	PURCHASE	20.00	750K	15M	5.11M
Mar 30, 2021	JEFFRIES SEAN	PURCHASE	20.00	3.05K	61K	3.05K
Mar 30, 2021	SR ONE CAPITAL FUND I AGGREGATOR LP	PURCHASE	20.00	250K	5M	5.63M
Mar 30, 2021	WILLIAM ARSANI	PURCHASE	20.00	700K	14M	2.73M

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES217.63K1

NET SHARES-217.63K1

SHARES HELD1M1

% NET SHARES-121.76%0%

Frequently Asked Questions