How many institutions own DFTX stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own DFTX shares is 358, representing 73.97% of the company's common stock.

Who are the major shareholders selling Definium Therapeutics, Inc. stock?

DEUTSCHE BANK AG\, in the last quarter, reduced its stake in DFTX by -65.29% restricting it's holding to 142.95 thousand shares of worth nearly $6.72M. BIT CAPITAL GMBH also lessened -53.83% of the DFTX shares from its portfolio, reducing its holding to 128.13 thousand shares of worth $6.03M. DEEP TRACK CAPITAL, LP also shunned DFTX shares holding by -8.33% last quarter which brought its holding to 2.75 million shares worth $129.36M.

Investors who are buying DFTX stock?

As per its latest 13F filing, EMERALD MUTUAL FUND ADVISERS TRUST increased its stake in DFTX by 100% in the last quarter. The institutional holder raised its holding to 121.25 thousand shares having worth more than $5.70M. JUPITER TOPCO LLC also added 100% more shares of DFTX to its portfolio, raising its holding to 5.62 million shares of worth $264.00M. VANGUARD PORTFOLIO MANAGEMENT LLC also increased its DFTX shares holding by 88.9% which brought its holding to 1.65 million shares worth $77.54M.

DFTX's major insiders: who are they?

The insider with the most stakes in DFTX is Barrow Robert , Chief Executive Officer at the company. Additionally, DFTX stock is highly held by Chief Medical Officer Karlin Daniel and Chief Legal Officer Sullivan Mark among others.

Did an insider recently sell DFTX stock?

Company executives, directors, and other insiders own 1.33% percent of Definium Therapeutics, Inc.'s stock. Within the last six months, there have been 9 transaction(s) in which DFTX insiders have sold stock, totaling 120.31K shares. Insiders that have sold shares include BARROW ROBERT, ROBERTS BRANDI, and KARLIN DANIEL.

Which insider recently purchased DFTX stock?

There have been 0 transaction(s) during the past 6-months in which Definium Therapeutics, Inc. insiders have bought stock, totalling 0 shares

How much of DFTX does insiders own?

Around 5.24M Definium Therapeutics, Inc. shares are held by insiders, which represents about 1.33% of DFTX stock.

Who is the insider with the largest stake?

DFTX Chief Executive Officer, Barrow Robert holds the largest portfolio of the company's shares. DFTX shares owned by Barrow total nearly 1.49 million.

Which institution holds the most shares in DFTX?

EMERALD MUTUAL FUND ADVISERS TRUST is the largest institutional owner in DFTX which holds 121.25 thousand shares worth $5.70M or 0.11% of the total DFTX shares outstanding followed by JUPITER TOPCO LLC with ownership of 5.62 million shares representing 5.07% of the DFTX ownership. VANGUARD PORTFOLIO MANAGEMENT LLC is the third largest stakeholder with 1.65 million shares or 1.49% of the ownership worth more than $77.54M.

Is Definium Therapeutics, Inc. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the DFTX is concerned, it is a stock which is optionable.

Is there a short position on DFTX's shares?

Number of DFTX shares short is 10.74M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding DFTX shares are there?

As of today, 134.37M shares of DFTX are outstanding.

Is there many float in DFTX stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, DFTX has 124.50M shares in float.

DFTX short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for DFTX is 5.24.

Definium Therapeutics (DFTX) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares8.09

Short Percent Of Float8.15

Shares Outstanding134.37M

Shares Float124.50M

Shares Short10.74M

Short Ratio5.24

8.15%

Short % of Float

8.09%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

1.33% Percentage of Shares held by All Insiders

73.97% Percentage of Shares held by All Institutions

74.96% Percentage of Float held by Institutions

358

Number of Institutions Holding Shares

Institutional Ownership

About 73.97% of DFTX shares are held by financial institutions. EMERALD MUTUAL FUND ADVISERS TRUST is the top corporate investor, holding 121.25K shares valued at $5.70M. A 0.11% stake in Definium Therapeutics, Inc. is owned by the company. JUPITER TOPCO LLC owns 5.62M shares valued at $264.00M, which translates its holding of 5.07% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Jun 30, 2026	EMERALD MUTUAL FUND ADVISERS TRUST	0.11%	121.25K	5.7M	121.25K	+100.00%
Jun 30, 2026	JUPITER TOPCO LLC	5.07%	5.62M	264M	5.62M	+100.00%
Jun 30, 2026	VANGUARD PORTFOLIO MANAGEMENT LLC	1.49%	1.65M	77.54M	775.76K	+88.90%
Jun 30, 2026	BLACKROCK, INC.	10.15%	11.23M	528.39M	2.75M	+32.46%
Jun 30, 2026	CAPITAL WORLD INVESTORS	4.85%	5.37M	252.5M	5.37M	+100.00%
Jun 30, 2026	FMR LLC	4.29%	4.75M	223.58M	2.94M	+162.65%
Jun 30, 2026	VANGUARD CAPITAL MANAGEMENT LLC	1.34%	1.49M	69.92M	389.48K	+35.50%
Jun 30, 2026	SIREN, L.L.C.	1.28%	1.42M	66.77M	500K	+54.38%
Jun 30, 2026	MARSHALL WACE, LLP	1.17%	1.3M	61.1M	98.12K	+8.17%
Jun 30, 2026	NORTHERN TRUST CORP	1.06%	1.17M	55M	370.25K	+46.34%
Jun 30, 2026	NUVEEN, LLC	1%	1.11M	51.99M	407.18K	+58.33%
Jun 30, 2026	VANGUARD FIDUCIARY TRUST CO	0.75%	827.69K	38.93M	251.76K	+43.71%
Jun 30, 2026	BANK OF NEW YORK MELLON CORP	0.7%	777.27K	36.56M	24.35K	+3.23%
Jun 30, 2026	NEUBERGER BERMAN GROUP LLC	0.62%	687.54K	32.34M	554.17K	+415.52%
Jun 30, 2026	MORGAN STANLEY	0.42%	454.91K	21.4M	16.34K	+3.73%
Jun 30, 2026	SILVERARC CAPITAL MANAGEMENT, LLC	0.37%	400K	18.82M	400K	+100.00%
Jun 30, 2026	ASSETMARK, INC	0.36%	396.54K	18.65M	396.54K	+100.00%
Jun 30, 2026	SILVERBACK ASSET MANAGEMENT LLC	0.27%	294.4K	13.85M	0	0
Jun 30, 2026	TFG ASSET MANAGEMENT GP LTD	0.26%	286.99K	13.5M	87K	+43.50%
Jun 30, 2026	JPMORGAN CHASE & CO	0.24%	265.96K	12.38M	1.41K	+0.53%
Jun 30, 2026	SWISS NATIONAL BANK	0.2%	221.2K	10.41M	62.8K	+39.65%
Jun 30, 2026	UBS ASSET MANAGEMENT AMERICAS INC	0.19%	211.18K	9.93M	208.77K	+8,651.89%
Jun 30, 2026	TD ASSET MANAGEMENT INC	0.19%	209.46K	9.85M	209.46K	+100.00%
Jun 30, 2026	EMERALD ADVISERS, LLC	0.16%	178.75K	8.41M	178.75K	+100.00%
Jun 30, 2026	ABRDN PLC	0.16%	175K	8.23M	175K	+100.00%
Jun 30, 2026	RHUMBLINE ADVISERS	0.15%	158.1K	7.44M	38.12K	+31.78%
Jun 30, 2026	RUSSELL INVESTMENTS GROUP, LTD.	0.14%	153.48K	7.22M	34.01K	+28.47%
Jun 30, 2026	DEUTSCHE BANK AG\	0.13%	142.95K	6.72M	-268.89K	-65.29%
Jun 30, 2026	BIT CAPITAL GMBH	0.12%	128.13K	6.03M	-149.38K	-53.83%
Jun 30, 2026	ATIKA CAPITAL MANAGEMENT LLC	0.11%	122K	5.74M	122K	+100.00%
Jun 30, 2026	ADVISORSHARES INVESTMENTS LLC	0.11%	121.38K	5.71M	30.08K	+32.95%
Jun 30, 2026	EAM INVESTORS, LLC	0.11%	120.93K	5.69M	120.93K	+100.00%
Jun 30, 2026	ALPS ADVISORS INC	0.1%	110.39K	5.19M	110.39K	+100.00%
Jun 30, 2026	BNP PARIBAS ARBITRAGE, SNC	0.09%	96.51K	4.54M	73.15K	+313.21%
Jun 30, 2026	VOYA INVESTMENT MANAGEMENT LLC	0.09%	95.17K	4.48M	78.78K	+480.85%
Jun 30, 2026	PIER CAPITAL, LLC	0.08%	88.6K	4.17M	88.6K	+100.00%
Jun 30, 2026	LPL FINANCIAL LLC	0.08%	86.14K	4.05M	7.87K	+10.05%
Jun 30, 2026	FORE CAPITAL, LLC	0.07%	80K	3.76M	80K	+100.00%
Jun 30, 2026	CITIGROUP INC	0.07%	79.55K	3.74M	53.06K	+200.34%
Jun 30, 2026	VANGUARD ASSET MANAGEMENT, LTD	0.07%	78.6K	3.7M	24.59K	+45.51%
Jun 30, 2026	QUANTINNO CAPITAL MANAGEMENT LP	0.07%	70.68K	3.32M	30.72K	+76.89%
Jun 30, 2026	ROCKEFELLER CAPITAL MANAGEMENT L.P.	0.06%	70.11K	3.3M	14.91K	+27.00%
Jun 30, 2026	PLATINUM INVESTMENT MANAGEMENT LTD	0.06%	70K	3.29M	0	0
Jun 30, 2026	GEODE CAPITAL MANAGEMENT, LLC	3.29%	3.64M	171.48M	1.15M	+46.06%
Jun 30, 2026	STATE STREET CORP	2.77%	3.07M	144.2M	593.52K	+24.01%
Jun 30, 2026	DEEP TRACK CAPITAL, LP	2.48%	2.75M	129.36M	-250K	-8.33%
Jun 30, 2026	CITADEL ADVISORS LLC	1.53%	1.69M	79.43M	355.15K	+26.63%
Jun 30, 2026	RA CAPITAL MANAGEMENT, L.P.	1.36%	1.5M	70.56M	1.5M	+100.00%
Jun 30, 2026	SUSQUEHANNA INTERNATIONAL GROUP, LLP	1.25%	1.39M	65.22M	546.4K	+65.05%
Jun 30, 2026	AMERIPRISE FINANCIAL INC	1.04%	1.15M	54.02M	181.76K	+18.80%
Jun 30, 2026	SIXTH STREET PARTNERS MANAGEMENT COMPANY, L.P.	0.98%	1.08M	50.97M	1.08M	+100.00%
Jun 30, 2026	WOODLINE PARTNERS LP	0.91%	1M	47.21M	250.85K	+33.32%
Jun 30, 2026	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.9%	1M	47.04M	-150K	-13.04%
Jun 30, 2026	BOXER CAPITAL MANAGEMENT, LLC	0.9%	998.5K	46.97M	400K	+66.83%
Jun 30, 2026	TWO SIGMA INVESTMENTS, LP	0.83%	921.82K	43.36M	-279.79K	-23.28%
Jun 30, 2026	BALYASNY ASSET MANAGEMENT L.P.	0.81%	897.66K	42.23M	-376.56K	-29.55%
Jun 30, 2026	AWM INVESTMENT COMPANY, INC.	0.71%	784.8K	36.92M	-292.09K	-27.12%
Jun 30, 2026	POLAR CAPITAL HOLDINGS PLC	0.7%	777.25K	36.56M	777.25K	+100.00%
Jun 30, 2026	EVENTIDE ASSET MANAGEMENT, LLC	0.64%	710K	33.4M	23.84K	+3.47%
Jun 30, 2026	QUBE RESEARCH & TECHNOLOGIES LTD	0.62%	682.9K	32.12M	256.85K	+60.28%
Jun 30, 2026	CANDRIAM S.C.A.	0.56%	614.43K	28.87M	-679.2K	-52.50%
Jun 30, 2026	ARROWMARK COLORADO HOLDINGS LLC	0.51%	564.07K	26.53M	-1.03M	-64.63%
Jun 30, 2026	CATALIO CAPITAL MANAGEMENT, LP	0.51%	562.67K	26.47M	-475.31K	-45.79%
Jun 30, 2026	BAMCO INC /NY/	0.47%	520.11K	24.47M	520.11K	+100.00%
Jun 30, 2026	UBS GROUP AG	0.45%	499.47K	23.49M	5.49K	+1.11%
Jun 30, 2026	FRANKLIN RESOURCES INC	0.44%	486.22K	22.87M	486.22K	+100.00%
Jun 30, 2026	POINT72 ASSET MANAGEMENT, L.P.	0.44%	483.98K	22.77M	308.49K	+175.79%
Jun 30, 2026	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.98%	1.08M	50.97M	274.86K	+33.99%
Jun 30, 2026	HOLOCENE ADVISORS, LP	0.72%	796.57K	37.47M	-295.39K	-27.05%
Jun 30, 2026	BLACKSTONE INC.	0.51%	561.61K	26.42M	52.94K	+10.41%
Jun 30, 2026	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.5%	550K	25.87M	150K	+37.50%
Jun 30, 2026	AVORO CAPITAL ADVISORS LLC	6.49%	7.19M	338.17M	2.19M	+43.78%
Jun 30, 2026	DRIEHAUS CAPITAL MANAGEMENT LLC	6.18%	6.85M	322M	933.39K	+15.79%
Jun 30, 2026	COMMODORE CAPITAL LP	1.81%	2M	94.08M	0	0
Jun 30, 2026	ALLIANCEBERNSTEIN L.P.	1.63%	1.8M	34.08M	1.71M	+1,866.44%
Jun 30, 2026	GOLDMAN SACHS GROUP INC	1.63%	1.8M	84.71M	125.44K	+7.49%
Jun 30, 2026		1.52%	1.65M	77.54M	775.76K	+88.90%
Jun 30, 2026	PRICE T ROWE ASSOCIATES INC /MD/	4.2%	4.65M	218.83M	4.58M	+6,545.67%
Jun 30, 2026	CAPITAL INTERNATIONAL INVESTORS	2.68%	2.96M	139.4M	2.96M	+100.00%
Jun 30, 2026	OCTAGON CAPITAL ADVISORS LP	2.67%	2.95M	138.77M	510K	+20.90%
Jun 30, 2026	WELLINGTON MANAGEMENT GROUP LLP	2.67%	2.95M	138.76M	1.64M	+126.08%
Mar 31, 2026	NORTHERN TRUST CORP	0.73%	798.99K	15.1M	798.99K	+100.00%
Mar 31, 2026	BOXER CAPITAL MANAGEMENT, LLC	0.55%	598.5K	11.31M	598.5K	+100.00%
Mar 31, 2026	BIT CAPITAL GMBH	0.31%	277.51K	5.24M	277.51K	+100.00%
Mar 31, 2026	JPMORGAN CHASE & CO	0.3%	264.55K	4.63M	264.55K	+100.00%
Mar 31, 2026	JANE STREET GROUP, LLC	0.06%	52.7K	996.03K	52.7K	+100.00%
Mar 31, 2026	ROYCE & ASSOCIATES LP	0.26%	234.05K	4.42M	234.05K	+100.00%
Mar 31, 2026	SEVEN GRAND MANAGERS, LLC	0.25%	225K	4.25M	225K	+100.00%
Mar 31, 2026	SWISS NATIONAL BANK	0.18%	158.4K	2.99M	158.4K	+100.00%
Mar 31, 2026	NEUBERGER BERMAN GROUP LLC	0.15%	133.37K	2.52M	133.37K	+100.00%
Mar 31, 2026	ROSALIND ADVISORS, INC.	0.14%	125K	2.36M	125K	+100.00%
Mar 31, 2026	RHUMBLINE ADVISERS	0.13%	119.97K	2.27M	119.97K	+100.00%
Mar 31, 2026	RUSSELL INVESTMENTS GROUP, LTD.	0.13%	119.46K	2.26M	119.46K	+100.00%
Mar 31, 2026	ADVISORSHARES INVESTMENTS LLC	0.1%	91.3K	1.73M	91.3K	+100.00%
Mar 31, 2026	AWM INVESTMENT COMPANY, INC.	0.99%	1.08M	20.35M	-313.77K	-22.56%
Mar 31, 2026	CATALIO CAPITAL MANAGEMENT, LP	0.95%	1.04M	19.62M	1.04M	+100.00%
Mar 31, 2026	AMERIPRISE FINANCIAL INC	1.08%	966.61K	18.27M	966.61K	+100.00%
Mar 31, 2026	HRT FINANCIAL LP	0.1%	89.14K	1.68M	89.14K	+100.00%
Mar 31, 2026	SUPERSTRING CAPITAL MANAGEMENT LP	0.32%	351.46K	6.64M	351.46K	+100.00%
Mar 31, 2026	SOFINNOVA INVESTMENTS, INC.	0.32%	344.17K	6.5M	344.17K	+100.00%
Mar 31, 2026	PATIENT SQUARE CAPITAL LP	0.3%	331K	6.26M	331K	+100.00%
Mar 31, 2026	STEMPOINT CAPITAL LP	0.3%	325.48K	6.15M	325.48K	+100.00%
Mar 31, 2026	MARSHALL WACE, LLP	1.1%	1.2M	22.7M	-1.77M	-59.65%
Mar 31, 2026	HOLOCENE ADVISORS, LP	1%	1.09M	20.64M	1.09M	+100.00%
Mar 31, 2026	SIREN, L.L.C.	0.85%	919.49K	17.38M	919.49K	+100.00%
Mar 31, 2026	BANK OF NEW YORK MELLON CORP	0.69%	752.92K	14.23M	752.92K	+100.00%
Mar 31, 2026	INVESCO LTD.	0.1%	88.12K	1.67M	88.12K	+100.00%
Mar 31, 2026	GROUP ONE TRADING, L.P.	0.1%	87.83K	1.66M	87.83K	+100.00%
Mar 31, 2026	LPL FINANCIAL LLC	0.09%	78.27K	1.48M	78.27K	+100.00%
Mar 31, 2026	PLATINUM INVESTMENT MANAGEMENT LTD	0.08%	70K	1.32M	70K	+100.00%
Mar 31, 2026	LEGAL & GENERAL GROUP PLC	0.07%	59.8K	1.13M	59.8K	+100.00%
Mar 31, 2026	ROCKEFELLER CAPITAL MANAGEMENT L.P.	0.06%	55.21K	1.04M	55.21K	+100.00%
Mar 31, 2026	METLIFE INVESTMENT MANAGEMENT, LLC	0.06%	54.26K	1.03M	54.26K	+100.00%
Mar 31, 2026	VANGUARD ASSET MANAGEMENT, LTD	0.06%	54.02K	1.02M	54.02K	+100.00%
Mar 31, 2026	BLAIR WILLIAM & CO/IL	0.06%	53.7K	1.01M	53.7K	+100.00%
Mar 31, 2026	KESTRA PRIVATE WEALTH SERVICES, LLC	0.06%	50.59K	956.11K	50.59K	+100.00%
Mar 31, 2026	NISA INVESTMENT ADVISORS, LLC	0.05%	48.9K	924.27K	48.9K	+100.00%
Mar 31, 2026	VANGUARD GLOBAL ADVISERS, LLC	0.05%	48.04K	908.03K	48.04K	+100.00%
Mar 31, 2026	ALLSTATE CORP	0.05%	45.37K	857.42K	45.37K	+100.00%
Mar 31, 2026	CENTERBOOK PARTNERS LP	0.05%	42.83K	809.47K	42.83K	+100.00%
Mar 31, 2026	SIMPLEX TRADING, LLC	0.05%	41.16K	777.85M	41.16K	+100.00%
Mar 31, 2026	SCOTIA CAPITAL INC.	0.05%	40.55K	766.43K	40.55K	+100.00%
Mar 31, 2026	WELLS FARGO & COMPANY/MN	0.04%	39.97K	755.49K	39.97K	+100.00%
Mar 31, 2026	JENNISON ASSOCIATES LLC	0.04%	39.96K	755.19K	39.96K	+100.00%
Mar 31, 2026	PALUMBO WEALTH MANAGEMENT LLC	0.04%	37.97K	717.56K	37.97K	+100.00%
Mar 31, 2026	CAXTON ASSOCIATES LLP	0.04%	37.26K	704.12K	37.26K	+100.00%
Mar 31, 2026	WALLEYE CAPITAL LLC	0.04%	35.49K	670.67K	35.49K	+100.00%
Mar 31, 2026	MARINER, LLC	0.04%	34.85K	658.64K	34.85K	+100.00%
Mar 31, 2026	VANGUARD FIDUCIARY TRUST CO	0.53%	575.94K	10.89M	575.94K	+100.00%
Mar 31, 2026	ENSIGN PEAK ADVISORS, INC	0.5%	546.78K	10.33M	284.78K	+108.70%
Mar 31, 2026	BLACKSTONE INC.	0.47%	508.67K	9.61M	508.67K	+100.00%
Mar 31, 2026	MORGAN STANLEY	0.4%	438.57K	8.29M	438.57K	+100.00%
Mar 31, 2026	RTW INVESTMENTS, LP	0.34%	300K	5.67M	300K	+100.00%
Mar 31, 2026	SILVERBACK ASSET MANAGEMENT LLC	0.33%	294.4K	5.56M	294.4K	+100.00%
Mar 31, 2026	DRIEHAUS CAPITAL MANAGEMENT LLC	5.43%	5.91M	111.73M	-625.31K	-9.57%
Mar 31, 2026	VANGUARD CAPITAL MANAGEMENT LLC	1.01%	1.1M	20.73M	1.1M	+100.00%
Mar 31, 2026	BLACKROCK, INC.	7.8%	8.48M	160.28M	8.48M	+100.00%
Mar 31, 2026	DEUTSCHE BANK AG\	0.38%	411.83K	7.78M	411.83K	+100.00%
Mar 31, 2026	QUBE RESEARCH & TECHNOLOGIES LTD	0.39%	426.06K	8.05M	426.06K	+100.00%
Mar 31, 2026	AVORO CAPITAL ADVISORS LLC	4.6%	5M	94.5M	5M	+100.00%
Mar 31, 2026	DEEP TRACK CAPITAL, LP	2.76%	3M	56.7M	3M	+100.00%
Mar 31, 2026	GEODE CAPITAL MANAGEMENT, LLC	2.29%	2.5M	47.17M	2.5M	+100.00%
Mar 31, 2026	STATE STREET CORP	2.27%	2.47M	46.72M	2.47M	+100.00%
Mar 31, 2026	OCTAGON CAPITAL ADVISORS LP	2.24%	2.44M	46.12M	2.44M	+100.00%
Mar 31, 2026	GOLDMAN SACHS GROUP INC	1.54%	1.68M	31.67M	1.68M	+100.00%
Mar 31, 2026	ADAGE CAPITAL PARTNERS GP, L.L.C.	1.06%	1.15M	21.74M	1.15M	+100.00%
Mar 31, 2026		0.8%	872.67K	16.49M	872.67K	+100.00%
Mar 31, 2026	MILLENNIUM MANAGEMENT LLC	0.78%	846.9K	16.01M	846.9K	+100.00%
Mar 31, 2026	JANUS HENDERSON GROUP PLC	3.27%	3.56M	67.23M	3.56M	+100.00%
Mar 31, 2026	COMMODORE CAPITAL LP	1.84%	2M	37.8M	2M	+100.00%
Mar 31, 2026	FMR LLC	1.66%	1.81M	34.2M	1.81M	+100.00%
Mar 31, 2026	WELLINGTON MANAGEMENT GROUP LLP	1.2%	1.3M	24.66M	1.3M	+100.00%
Mar 31, 2026	BALYASNY ASSET MANAGEMENT L.P.	1.17%	1.27M	24.08M	1.27M	+100.00%
Mar 31, 2026	UBS GROUP AG	0.45%	493.98K	9.34M	493.98K	+100.00%
Mar 31, 2026	ARROWMARK COLORADO HOLDINGS LLC	1.47%	1.59M	30.14M	1.59M	+100.00%
Mar 31, 2026	CITADEL ADVISORS LLC	1.23%	1.33M	25.2M	1.33M	+100.00%
Mar 31, 2026	CANDRIAM S.C.A.	1.19%	1.29M	24.45M	1.29M	+100.00%
Mar 31, 2026	TWO SIGMA INVESTMENTS, LP	1.1%	1.2M	22.71M	1.2M	+100.00%
Mar 31, 2026	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.77%	840K	15.88M	840K	+100.00%
Mar 31, 2026	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.74%	808.72K	15.28M	808.72K	+100.00%
Mar 31, 2026	ORBIMED ADVISORS LLC	0.74%	804K	15.2M	804K	+100.00%
Mar 31, 2026	WOODLINE PARTNERS LP	0.69%	752.79K	14.23M	752.79K	+100.00%
Mar 31, 2026	NUVEEN, LLC	0.64%	698.13K	13.19M	698.13K	+100.00%
Mar 31, 2026	EVENTIDE ASSET MANAGEMENT, LLC	0.63%	686.16K	12.97M	686.16K	+100.00%
Mar 31, 2026	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.37%	400K	7.56M	400K	+100.00%
Mar 31, 2026	TRI LOCUM PARTNERS LP	0.34%	369.59K	6.99M	369.59K	+100.00%
Dec 31, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	7.32%	6.54M	87.53M	6.54M	+100.00%
Dec 31, 2025	MARSHALL WACE, LLP	3.33%	2.98M	39.84M	2.98M	+100.00%
Dec 31, 2025	AWM INVESTMENT COMPANY, INC.	1.56%	1.39M	18.62M	1.39M	+100.00%
Dec 31, 2025	ENSIGN PEAK ADVISORS, INC	0.29%	262K	3.51M	262K	+100.00%
Dec 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	0.06%	52.23K	700K	52.23K	+100.00%
Dec 31, 2025	DARK FOREST CAPITAL MANAGEMENT LP	0.03%	30.66K	410.55K	30.66K	+100.00%
Dec 31, 2025	SOUND INCOME STRATEGIES, LLC	0%	3.69K	55.54K	3.69K	+100.00%
Dec 31, 2025		0%	391	6.82K	391	+100.00%

Insiders

Among the DFTX insiders holding of 1.33% of the stake in company, BARROW ROBERT, Chief Executive Officer, holds the largest shares of 1.49M. KARLIN DANIEL, Chief Medical Officer, is the second largest DFTX insider with ownership of 503.28K shares. SULLIVAN MARK, Chief Legal Officer, stands third with possession of 320.57K shares of that stake.

Insiders	Designation	Shares Held
BARROW ROBERT	Chief Executive Officer	1.49M
KARLIN DANIEL	Chief Medical Officer	503.28K
SULLIVAN MARK	Chief Legal Officer	320.57K
ROBERTS BRANDI	Chief Financial Officer	209.49K
WILEY MATTHEW T.	Chief Commercial Officer	174.63K

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Sep 03, 2026	BARROW ROBERT	SALE	37.94	19.02K	721.73K	1.49M
Jun 25, 2026	ROBERTS BRANDI	SALE	45.03	3.01K	135.68K	209.49K
Jun 25, 2026	BARROW ROBERT	SALE	45.03	29.21K	1.32M	1.1M
Jun 25, 2026	KARLIN DANIEL	SALE	45.03	10.04K	451.88K	503.28K
Jun 25, 2026	WILEY MATTHEW T.	SALE	45.03	2.87K	129.1K	174.63K
Jun 25, 2026	SULLIVAN MARK	SALE	45.03	13.01K	585.75K	320.57K
Mar 25, 2026	BARROW ROBERT	SALE	18.47	24.43K	451.24K	752.45K
Mar 25, 2026	SULLIVAN MARK	SALE	18.47	10.7K	197.67K	271.08K
Mar 25, 2026	KARLIN DANIEL	SALE	18.47	8.02K	148.09K	413.32K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES120.31K9

NET SHARES-120.31K9

SHARES HELD5.24M9

% NET SHARES-102.3%0%

Frequently Asked Questions