How many institutions own DAWN stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own DAWN shares is 251, representing 85.68% of the company's common stock.

Who are the major shareholders selling Day One Biopharmaceuticals, Inc. stock?

UBS GROUP AG, in the last quarter, reduced its stake in DAWN by -18.59% restricting it's holding to 170.73 thousand shares of worth nearly $1.59M. FISHER ASSET MANAGEMENT, LLC also lessened -12.87% of the DAWN shares from its portfolio, reducing its holding to 191.82 thousand shares of worth $1.79M. NORTHERN TRUST CORP also shunned DAWN shares holding by -1.99% last quarter which brought its holding to 617.04 thousand shares worth $5.75M.

Investors who are buying DAWN stock?

As per its latest 13F filing, MASSACHUSETTS FINANCIAL SERVICES CO /MA/ increased its stake in DAWN by 100% in the last quarter. The institutional holder raised its holding to 150.93 thousand shares having worth more than $1.41M. RAFFERTY ASSET MANAGEMENT, LLC also added 23.07% more shares of DAWN to its portfolio, raising its holding to 157.01 thousand shares of worth $1.46M. CITADEL ADVISORS LLC also increased its DAWN shares holding by 105% which brought its holding to 1.36 million shares worth $12.67M.

DAWN's major insiders: who are they?

The insider with the most stakes in DAWN is Canaan XI L.P. , 10 percent owner at the company. Additionally, DAWN stock is highly held by HEAD OF R&D Blackman Samuel C. and 10 percent owner AI Day1 LLC among others.

Did an insider recently sell DAWN stock?

Company executives, directors, and other insiders own 16.94% percent of Day One Biopharmaceuticals, Inc.'s stock. Within the last six months, there have been 9 transaction(s) in which DAWN insiders have sold stock, totaling 64.46K shares. Insiders that have sold shares include MERENDINO LAUREN, DUBOW ADAM, and YORK CHARLES N II.

Which insider recently purchased DAWN stock?

There have been 0 transaction(s) during the past 6-months in which Day One Biopharmaceuticals, Inc. insiders have bought stock, totalling 0 shares

How much of DAWN does insiders own?

Around 1.24M Day One Biopharmaceuticals, Inc. shares are held by insiders, which represents about 16.94% of DAWN stock.

Who is the insider with the largest stake?

DAWN 10 percent owner, Canaan XI L.P. holds the largest portfolio of the company's shares. DAWN shares owned by Canaan total nearly 8.46 million.

Which institution holds the most shares in DAWN?

MASSACHUSETTS FINANCIAL SERVICES CO /MA/ is the largest institutional owner in DAWN which holds 150.93 thousand shares worth $1.41M or 0.15% of the total DAWN shares outstanding followed by RAFFERTY ASSET MANAGEMENT, LLC with ownership of 157.01 thousand shares representing 0.15% of the DAWN ownership. UBS GROUP AG is the third largest stakeholder with 170.73 thousand shares or 0.17% of the ownership worth more than $1.59M.

Is Day One Biopharmaceuticals, Inc. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the DAWN is concerned, it is a stock which is optionable.

Is there a short position on DAWN's shares?

Number of DAWN shares short is 11.28M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding DAWN shares are there?

As of today, 102.43M shares of DAWN are outstanding.

Is there many float in DAWN stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, DAWN has 78.72M shares in float.

DAWN short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for DAWN is 5.87.

Day One Biopharmaceuticals (DAWN) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares11.01

Short Percent Of Float16.3

Shares Outstanding102.43M

Shares Float78.72M

Shares Short11.28M

Short Ratio5.87

16.3%

Short % of Float

11.01%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

16.94% Percentage of Shares held by All Insiders

85.68% Percentage of Shares held by All Institutions

103.15% Percentage of Float held by Institutions

251

Number of Institutions Holding Shares

Institutional Ownership

About 85.68% of DAWN shares are held by financial institutions. MASSACHUSETTS FINANCIAL SERVICES CO /MA/ is the top corporate investor, holding 150.93K shares valued at $1.41M. A 0.15% stake in Day One Biopharmaceuticals, Inc. is owned by the company. RAFFERTY ASSET MANAGEMENT, LLC owns 157.01K shares valued at $1.46M, which translates its holding of 0.15% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Dec 31, 2025	MASSACHUSETTS FINANCIAL SERVICES CO /MA/	0.15%	150.93K	1.41M	150.93K	+100.00%
Dec 31, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.15%	157.01K	1.46M	29.43K	+23.07%
Dec 31, 2025	UBS GROUP AG	0.17%	170.73K	1.59M	-38.99K	-18.59%
Dec 31, 2025	CITADEL ADVISORS LLC	1.32%	1.36M	12.67M	696.4K	+105.00%
Dec 31, 2025	FISHER ASSET MANAGEMENT, LLC	0.19%	191.82K	1.79M	-28.34K	-12.87%
Dec 31, 2025	GOLDMAN SACHS GROUP INC	1.46%	1.51M	14.04M	134.8K	+9.83%
Dec 31, 2025	SG AMERICAS SECURITIES, LLC	0.34%	350.09K	3.26M	323.75K	+1,228.87%
Dec 31, 2025	AQR CAPITAL MANAGEMENT LLC	0.42%	431.76K	4.02M	323.28K	+298.02%
Dec 31, 2025	MORGAN STANLEY	1.5%	1.55M	14.45M	246.25K	+18.88%
Dec 31, 2025	NORGES BANK	0.16%	169K	1.58M	169K	+100.00%
Dec 31, 2025	HUDSON BAY CAPITAL MANAGEMENT LP	1.64%	1.7M	15.84M	380K	+28.79%
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.82%	1.88M	17.5M	116.57K	+6.62%
Dec 31, 2025	AIGH CAPITAL MANAGEMENT LLC	1.93%	1.99M	18.57M	471.53K	+31.01%
Dec 31, 2025	PICTET ASSET MANAGEMENT HOLDING SA	2.89%	2.99M	27.87M	617.67K	+26.03%
Dec 31, 2025	Y-INTERCEPT (HONG KONG) LTD	0.27%	282.03K	2.63M	282.03K	+100.00%
Dec 31, 2025	KENNEDY CAPITAL MANAGEMENT LLC	0.53%	542.85K	5.06M	2.46K	+0.46%
Dec 31, 2025	NORTHERN TRUST CORP	0.6%	617.04K	5.75M	-12.56K	-1.99%
Dec 31, 2025	MAK CAPITAL ONE LLC	0.8%	826.21K	7.7M	-622.26K	-42.96%
Dec 31, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	1.44%	1.49M	13.85M	318.89K	+27.31%
Dec 31, 2025	DEUTSCHE BANK AG\	0.06%	57.01K	531.33K	15.51K	+37.36%
Dec 31, 2025	PROFUND ADVISORS LLC	0.06%	58.13K	541.76K	30.49K	+110.35%
Dec 31, 2025	LEGAL & GENERAL GROUP PLC	0.06%	63.67K	593.39K	6.8K	+11.97%
Dec 31, 2025	AMERICAN CENTURY COMPANIES INC	0.08%	78.93K	735.58K	45.06K	+133.06%
Dec 31, 2025	PERKINS CAPITAL MANAGEMENT INC	0.08%	84K	782.88K	1.75K	+2.13%
Dec 31, 2025	ALPS ADVISORS INC	0.08%	84.3K	785.71K	35.27K	+71.93%
Dec 31, 2025	CITIGROUP INC	0.1%	100K	932K	100K	+100.00%
Dec 31, 2025	LOS ANGELES CAPITAL MANAGEMENT LLC	0.1%	100.31K	706.21K	1.43K	+1.44%
Dec 31, 2025	SQUAREPOINT OPS LLC	0.1%	100.61K	937.7K	100.61K	+100.00%
Dec 31, 2025	RHUMBLINE ADVISERS	0.11%	111.68K	1.04M	-10.27K	-8.42%
Dec 31, 2025	WELLS FARGO & COMPANY/MN	0.11%	114.72K	1.07M	33.25K	+40.81%
Dec 31, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.12%	124.42K	1.16M	8.18K	+7.03%
Dec 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.44%	453.31K	4.22M	185.02K	+68.96%
Dec 31, 2025	NUVEEN, LLC	0.51%	522.46K	4.87M	372.08K	+247.44%
Dec 31, 2025	RENAISSANCE TECHNOLOGIES LLC	1.26%	1.31M	12.16M	399.61K	+44.13%
Dec 31, 2025	VANGUARD GROUP INC	6.08%	6.28M	58.55M	101.05K	+1.63%
Dec 31, 2025	ATLAS VENTURE LIFE SCIENCE ADVISORS, LLC	6.2%	6.41M	59.77M	-17.7K	-0.28%
Dec 31, 2025	BLACKROCK, INC.	8.55%	8.84M	82.37M	-163.88K	-1.82%
Dec 31, 2025	BALYASNY ASSET MANAGEMENT L.P.	1.44%	1.49M	13.89M	105.88K	+7.65%
Dec 31, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	3.6%	3.72M	34.7M	-982.28K	-20.88%
Dec 31, 2025	MAN GROUP PLC	0.19%	197.1K	1.84M	105.28K	+114.66%
Dec 31, 2025	STONEPINE CAPITAL MANAGEMENT, LLC	0.19%	200K	1.86M	-447.38K	-69.11%
Dec 31, 2025	BARCLAYS PLC	0.28%	292.33K	2.72M	-54.86K	-15.80%
Dec 31, 2025	HENNION & WALSH ASSET MANAGEMENT, INC.	0.3%	313.46K	2.92M	218.38K	+229.70%
Dec 31, 2025	HRT FINANCIAL LP	0.44%	450.94K	4.2M	129.56K	+40.31%
Dec 31, 2025	ALGERT GLOBAL LLC	0.52%	535.29K	4.99M	-781.75K	-59.36%
Dec 31, 2025	PALE FIRE CAPITAL SE	0.53%	544.06K	5.07M	241.6K	+79.88%
Dec 31, 2025	SCHRODER INVESTMENT MANAGEMENT GROUP	0.55%	569.62K	5.23M	299.41K	+110.80%
Dec 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.61%	633.69K	5.91M	23.63K	+3.87%
Dec 31, 2025	PARKMAN HEALTHCARE PARTNERS LLC	0.62%	645.54K	6.02M	343.8K	+113.94%
Dec 31, 2025	JUMP FINANCIAL, LLC	0.65%	667.12K	6.22M	394.57K	+144.77%
Dec 31, 2025	JACOBS LEVY EQUITY MANAGEMENT, INC	0.71%	729.28K	6.8M	729.28K	+100.00%
Dec 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.71%	737.66K	6.87M	708.81K	+2,456.53%
Dec 31, 2025	JANE STREET GROUP, LLC	0.82%	845.15K	7.88M	565.81K	+202.55%
Dec 31, 2025	DAFNA CAPITAL MANAGEMENT LLC	0.97%	999.16K	9.31M	0	0
Dec 31, 2025	BANK OF NEW YORK MELLON CORP	0.2%	211.55K	1.97M	-94.63K	-30.91%
Dec 31, 2025	CAPTION MANAGEMENT, LLC	0.22%	225K	2.1M	225K	+100.00%
Dec 31, 2025	GROUP ONE TRADING, L.P.	0.24%	253.14K	2.36M	253.14K	+100.00%
Dec 31, 2025	ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	0.25%	255.02K	2.38M	255.02K	+100.00%
Dec 31, 2025	STATE STREET CORP	4.15%	4.29M	39.98M	1.05M	+32.38%
Dec 31, 2025	VESTAL POINT CAPITAL, LP	5.03%	5.2M	48.46M	2.53M	+94.39%
Dec 31, 2025	FMR LLC	5.53%	5.72M	53.28M	-4.38M	-43.38%
Dec 31, 2025	JEFFERIES FINANCIAL GROUP INC.	1.08%	1.12M	10.45M	1.12M	+100.00%
Dec 31, 2025	MILLENNIUM MANAGEMENT LLC	1.31%	1.35M	12.58M	656.6K	+94.70%
Dec 31, 2025	LOGOS GLOBAL MANAGEMENT LP	0.29%	300K	2.8M	300K	+100.00%
Dec 31, 2025	SCHONFELD STRATEGIC ADVISORS LLC	0.29%	300.1K	2.8M	276.78K	+1,186.89%
Dec 31, 2025	DIMENSIONAL FUND ADVISORS LP	1%	1.04M	9.67M	-185.97K	-15.20%
Dec 31, 2025	BANK OF AMERICA CORP /DE/	1.05%	1.08M	10.1M	-108.03K	-9.06%
Dec 31, 2025	NOMURA HOLDINGS INC	0.14%	140K	1.3M	140K	+100.00%
Dec 31, 2025	SWISS NATIONAL BANK	0.14%	141.5K	1.32M	15.7K	+12.48%
Dec 31, 2025	GSA CAPITAL PARTNERS LLP	0.14%	142.81K	1.33M	142.81K	+100.00%
Dec 31, 2025	CATALYTIC WEALTH RIA, LLC	0.15%	150.03K	1.4M	100.03K	+200.06%
Sep 30, 2025	MARTINGALE ASSET MANAGEMENT L P	0.03%	33.7K	237.59M	-1.3K	-3.71%
Sep 30, 2025	AMERICAN CENTURY COMPANIES INC	0.03%	33.87K	238.75K	6.54K	+23.91%
Sep 30, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.04%	37.48K	264.22K	-6.96K	-15.67%
Sep 30, 2025	DIAMETRIC CAPITAL, LP	0.04%	38.47K	271.18K	-11.48K	-22.98%
Sep 30, 2025	DEUTSCHE BANK AG\	0.04%	41.5K	292.6K	-283.78K	-87.24%
Sep 30, 2025	CATALYTIC WEALTH RIA, LLC	0.05%	50K	352.5K	-30K	-37.50%
Sep 30, 2025	ALPS ADVISORS INC	0.05%	49.04K	345.7K	-5.67K	-10.37%
Sep 30, 2025	ERSTE ASSET MANAGEMENT GMBH	0.05%	51.2K	357.89K	0	0
Sep 30, 2025	LEGAL & GENERAL GROUP PLC	0.06%	56.86K	400.89K	0	0
Sep 30, 2025	JPMORGAN CHASE & CO	0.06%	65.68K	463.06K	-23.42K	-26.28%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0.08%	81.47K	574.35K	8.9K	+12.27%
Sep 30, 2025	PERKINS CAPITAL MANAGEMENT INC	0.08%	82.25K	579.86K	82.25K	+100.00%
Sep 30, 2025	DYNAMIC TECHNOLOGY LAB PRIVATE LTD	0.08%	87.54K	618K	4.32K	+5.19%
Sep 30, 2025	HENNION & WALSH ASSET MANAGEMENT, INC.	0.09%	95.07K	670.26K	-1.75K	-1.81%
Sep 30, 2025	INVESCO LTD.	0.1%	98.04K	691.2K	29.54K	+43.11%
Sep 30, 2025	LOS ANGELES CAPITAL MANAGEMENT LLC	0.1%	98.89K	697.17K	16.63K	+20.22%
Sep 30, 2025	HSBC HOLDINGS PLC	0.11%	109.78K	771.76K	-21.89K	-16.62%
Sep 30, 2025	BLACKROCK, INC.	8.73%	9M	63.46M	-828.98K	-8.43%
Sep 30, 2025	FMR LLC	9.8%	10.1M	71.19M	-1.25M	-10.98%
Sep 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	2.3%	2.37M	16.73M	-1.35M	-36.25%
Sep 30, 2025	BARCLAYS PLC	0.34%	347.19K	2.45M	-924	-0.27%
Sep 30, 2025	KENNEDY CAPITAL MANAGEMENT LLC	0.52%	540.38K	3.81M	86.86K	+19.15%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.26%	268.29K	1.89M	142.83K	+113.84%
Sep 30, 2025	HRT FINANCIAL LP	0.31%	321.38K	2.27M	321.38K	+100.00%
Sep 30, 2025	MILLENNIUM MANAGEMENT LLC	0.67%	693.32K	4.89M	-514.48K	-42.60%
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.88%	905.48K	6.38M	-95.06K	-9.50%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	1.16%	1.19M	8.4M	226.43K	+23.45%
Sep 30, 2025	MORGAN STANLEY	1.27%	1.3M	9.19M	-49.12K	-3.63%
Sep 30, 2025	ALGERT GLOBAL LLC	1.28%	1.32M	9.29M	411K	+45.36%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.71%	1.76M	12.42M	48.84K	+2.85%
Sep 30, 2025	FRANKLIN RESOURCES INC	3.37%	3.48M	24.51M	-620.6K	-15.15%
Sep 30, 2025	KNOTT DAVID M JR	0.13%	130.5K	920.03K	96.79K	+287.08%
Sep 30, 2025	DIMENSIONAL FUND ADVISORS LP	1.19%	1.22M	8.62M	-193.27K	-13.64%
Sep 30, 2025	HUDSON BAY CAPITAL MANAGEMENT LP	1.28%	1.32M	9.31M	23.3K	+1.80%
Sep 30, 2025	BALYASNY ASSET MANAGEMENT L.P.	1.34%	1.38M	9.76M	1.38M	+100.00%
Sep 30, 2025	AIGH CAPITAL MANAGEMENT LLC	1.48%	1.52M	10.72M	1.52M	+100.00%
Sep 30, 2025	ALYESKA INVESTMENT GROUP, L.P.	2.15%	2.21M	15.6M	-800K	-26.56%
Sep 30, 2025	MACQUARIE GROUP LTD	0.11%	110K	776K	0	0
Sep 30, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.11%	116.25K	819.53K	-59.17K	-33.73%
Sep 30, 2025	RHUMBLINE ADVISERS	0.12%	121.95K	859.7K	5.89K	+5.07%
Sep 30, 2025	SWISS NATIONAL BANK	0.12%	125.8K	886.89K	0	0
Sep 30, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.12%	127.58K	899.44K	28.89K	+29.27%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	1.33%	1.37M	9.67M	-319.85K	-18.91%
Sep 30, 2025	MAK CAPITAL ONE LLC	1.41%	1.45M	10.21M	1.45M	+100.00%
Sep 30, 2025	BRAIDWELL LP	2.12%	2.18M	15.38M	0	0
Sep 30, 2025	VESTAL POINT CAPITAL, LP	2.6%	2.68M	18.86M	-325K	-10.83%
Sep 30, 2025	STATE STREET CORP	3.14%	3.24M	22.85M	550.76K	+20.48%
Sep 30, 2025	RUBRIC CAPITAL MANAGEMENT LP	3.28%	3.38M	23.81M	3.38M	+100.00%
Sep 30, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	4.57%	4.71M	33.17M	982.28K	+26.38%
Sep 30, 2025	J. GOLDMAN & CO LP	0.55%	569.62K	4.02M	12.14K	+2.18%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.59%	610.06K	4.3M	31.3K	+5.41%
Sep 30, 2025	SCHRODER INVESTMENT MANAGEMENT GROUP	0.26%	270.22K	1.89M	90.08K	+50.01%
Sep 30, 2025	SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC	0.13%	138.42K	975.86K	-124.89K	-47.43%
Sep 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0.15%	150.35K	1.06M	6.9K	+4.81%
Sep 30, 2025	NUVEEN, LLC	0.15%	150.37K	1.06M	0	0
Sep 30, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.17%	175.37K	1.24M	0	0
Sep 30, 2025	QUEST PARTNERS LLC	0.18%	185.01K	1.3M	169.13K	+1,065.61%
Sep 30, 2025	FISHER ASSET MANAGEMENT, LLC	0.21%	220.16K	1.55M	-1.82K	-0.82%
Sep 30, 2025	TREXQUANT INVESTMENT LP	0.26%	266.58K	1.88M	151.15K	+130.95%
Sep 30, 2025	JUMP FINANCIAL, LLC	0.26%	272.55K	1.92M	272.55K	+100.00%
Sep 30, 2025	PARKWOOD LLC	0.27%	275K	1.94M	0	0
Sep 30, 2025	JANE STREET GROUP, LLC	0.27%	279.34K	1.97M	279.34K	+100.00%
Sep 30, 2025	PARKMAN HEALTHCARE PARTNERS LLC	0.29%	301.75K	2.13M	-198.25K	-39.65%
Sep 30, 2025	PALE FIRE CAPITAL SE	0.29%	302.47K	2.13M	267.62K	+768.09%
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.3%	306.18K	2.16M	-1.67K	-0.54%
Sep 30, 2025	STONEPINE CAPITAL MANAGEMENT, LLC	0.63%	647.38K	4.56M	197.38K	+43.86%
Sep 30, 2025	CITADEL ADVISORS LLC	0.64%	663.21K	4.68M	-40.43K	-5.75%
Sep 30, 2025	VANGUARD GROUP INC	6%	6.18M	43.58M	4.83K	+0.08%
Sep 30, 2025	ATLAS VENTURE LIFE SCIENCE ADVISORS, LLC	6.24%	6.43M	45.33M	0	0
Sep 30, 2025	UBS GROUP AG	0.2%	209.72K	1.48M	120.24K	+134.39%
Sep 30, 2025	NORTHERN TRUST CORP	0.61%	629.59K	4.44M	18.43K	+3.02%
Sep 30, 2025	DAFNA CAPITAL MANAGEMENT LLC	0.97%	999.16K	7.04M	120K	+13.65%
Sep 30, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	1.13%	1.17M	8.23M	223.47K	+23.67%
Sep 30, 2025	FOX RUN MANAGEMENT, L.L.C.	0.03%	25.93K	182.82K	25.93K	+100.00%
Sep 30, 2025	SG AMERICAS SECURITIES, LLC	0.03%	26.35K	186K	26.35K	+100.00%
Sep 30, 2025	PROFUND ADVISORS LLC	0.03%	27.64K	194.83K	6.69K	+31.91%
Sep 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.03%	31.27K	220.44K	-14.13K	-31.12%
Jun 30, 2025	ROYAL BANK OF CANADA	0.17%	174.97K	1.14M	-10.76K	-5.79%
Jun 30, 2025	NEOS INVESTMENT MANAGEMENT LLC	0.12%	124.31K	808.02K	33.19K	+36.42%
Jun 30, 2025	TREXQUANT INVESTMENT LP	0.11%	115.43K	750.28K	-89.36K	-43.63%
Jun 30, 2025	UBS OCONNOR LLC	0.1%	107.25K	697.12K	-6K	-5.30%
Jun 30, 2025	WOODLINE PARTNERS LP	0.1%	100.52K	653.35K	-112.64K	-52.84%
Jun 30, 2025	SCHONFELD STRATEGIC ADVISORS LLC	0.1%	99.59K	647.33K	34.07K	+51.99%
Jun 30, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.1%	98.69K	641.49K	-20.47K	-17.18%
Jun 30, 2025	HENNION & WALSH ASSET MANAGEMENT, INC.	0.09%	96.82K	629.34K	-41.15K	-29.82%
Jun 30, 2025	DYNAMIC TECHNOLOGY LAB PRIVATE LTD	0.08%	83.22K	541K	34.77K	+71.75%
Jun 30, 2025	LOS ANGELES CAPITAL MANAGEMENT LLC	0.08%	82.26K	534.67K	27.34K	+49.77%
Jun 30, 2025	D. E. SHAW & CO., INC.	0.08%	81.3K	528.47M	-1.77K	-2.13%
Jun 30, 2025	CATALYTIC WEALTH RIA, LLC	0.08%	80K	520K	80K	+100.00%
Jun 30, 2025	DARK FOREST CAPITAL MANAGEMENT LP	0.08%	78.42K	509.74K	78.42K	+100.00%
Jun 30, 2025	ALLIANCEBERNSTEIN L.P.	0.07%	67.79K	440.64M	0	0
Jun 30, 2025	VIRTUS INVESTMENT ADVISERS, INC.	0.06%	66.43K	431.78K	38.4K	+136.99%
Jun 30, 2025	NEBULA RESEARCH & DEVELOPMENT LLC	0.06%	60.67K	394.32K	3.53K	+6.18%
Jun 30, 2025	DRW SECURITIES, LLC	0.06%	57.8K	375.73K	57.8K	+100.00%
Jun 30, 2025	MAN GROUP PLC	0.06%	56.86K	369.6K	17.95K	+46.13%
Jun 30, 2025	BLACKROCK, INC.	9.54%	9.83M	63.9M	3.07M	+45.47%
Jun 30, 2025	ATLAS VENTURE LIFE SCIENCE ADVISORS, LLC	6.24%	6.43M	41.8M	0	0
Jun 30, 2025	MIRAE ASSET GLOBAL ETFS HOLDINGS LTD.	0.04%	44.24K	287.44K	6.25K	+16.46%
Jun 30, 2025	CAPTION MANAGEMENT, LLC	0.04%	40K	260K	0	0
Jun 30, 2025	TUDOR INVESTMENT CORP ET AL	0.04%	36.39K	236.56K	-14.4K	-28.35%
Jun 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.04%	45.4K	295.08K	-5.77K	-11.27%
Jun 30, 2025	FMR LLC	11%	11.34M	73.73M	-2.36M	-17.21%
Jun 30, 2025	VANGUARD GROUP INC	5.99%	6.18M	40.15M	233.25K	+3.92%
Jun 30, 2025	FRANKLIN RESOURCES INC	3.98%	4.1M	26.63M	79.26K	+1.97%
Jun 30, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	3.61%	3.72M	24.2M	762.39K	+25.75%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	1.64%	1.69M	10.99B	121.37K	+7.73%
Jun 30, 2025	MORGAN STANLEY	1.31%	1.35M	8.8B	643.73K	+90.74%
Jun 30, 2025	CITADEL ADVISORS LLC	0.68%	703.64K	4.57B	-635.37K	-47.45%
Jun 30, 2025	J. GOLDMAN & CO LP	0.54%	557.48K	3.62M	557.48K	+100.00%
Jun 30, 2025	KENNEDY CAPITAL MANAGEMENT LLC	0.44%	453.52K	2.95M	125.83K	+38.40%
Jun 30, 2025	STONEPINE CAPITAL MANAGEMENT, LLC	0.44%	450K	2.93M	101.18K	+29.01%
Jun 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.38%	391.28K	2.54M	391.28K	+100.00%
Jun 30, 2025	BARCLAYS PLC	0.34%	348.11K	2.26M	192.9K	+124.28%
Jun 30, 2025	AQR CAPITAL MANAGEMENT LLC	0.27%	279.85K	1.82B	-338.78K	-54.76%
Jun 30, 2025	ECOR1 CAPITAL, LLC	0.84%	862.07K	5.6M	0	0
Jun 30, 2025	ALPS ADVISORS INC	0.05%	54.71K	355.6K	-18.64K	-25.41%
Jun 30, 2025	DIAMETRIC CAPITAL, LP	0.05%	49.94K	324.62K	25.47K	+104.04%
Jun 30, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.92%	944.2K	6.14M	663.42K	+236.27%
Jun 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	3.61%	3.72M	24.2M	87.15K	+2.40%
Jun 30, 2025	ALGERT GLOBAL LLC	0.88%	906.04K	5.89M	534.66K	+143.97%
Jun 30, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.17%	175.42K	1.14M	63.14K	+56.23%
Jun 30, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.17%	175.37K	1.14M	-159.62K	-47.65%
Jun 30, 2025		0.15%	150.37K	977.42K	10.71K	+7.67%
Jun 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0.14%	143.45K	932.45K	127.11K	+777.93%
Jun 30, 2025	STATE OF WISCONSIN INVESTMENT BOARD	0.13%	136.28K	885.79K	53.02K	+63.68%
Jun 30, 2025	HSBC HOLDINGS PLC	0.13%	131.67K	845.97K	81.49K	+162.41%
Jun 30, 2025	ALYESKA INVESTMENT GROUP, L.P.	2.92%	3.01M	19.58M	-1.05M	-25.80%
Jun 30, 2025	VESTAL POINT CAPITAL, LP	2.91%	3M	19.5M	401.87K	+15.47%
Jun 30, 2025	STATE STREET CORP	2.61%	2.69M	17.48M	-17.01K	-0.63%
Jun 30, 2025	DIMENSIONAL FUND ADVISORS LP	1.37%	1.42M	9.21M	113.59K	+8.72%
Jun 30, 2025	HUDSON BAY CAPITAL MANAGEMENT LP	1.26%	1.3M	8.43M	146.3K	+12.72%
Jun 30, 2025	MILLENNIUM MANAGEMENT LLC	1.17%	1.21M	7.85M	-112.29K	-8.51%
Jun 30, 2025	SWISS NATIONAL BANK	0.12%	125.8K	817.7K	18.3K	+17.02%
Jun 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.12%	125.46K	815.5K	-36.54K	-22.56%
Jun 30, 2025	NUVEEN, LLC	0.15%	150.37K	977.42K	10.71K	+7.67%
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.09%	1.12M	7.29M	-52.46K	-4.47%
Jun 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.97%	1M	6.5M	652.1K	+187.15%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0.94%	965.42K	6.28M	-81.33K	-7.77%
Jun 30, 2025	DAFNA CAPITAL MANAGEMENT LLC	0.85%	879.16K	5.71M	147.8K	+20.21%
Jun 30, 2025	NORTHERN TRUST CORP	0.59%	611.16K	3.97M	75.16K	+14.02%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.56%	578.76K	3.76M	50.62K	+9.58%
Jun 30, 2025	PARKMAN HEALTHCARE PARTNERS LLC	0.49%	500K	3.25M	-543.16K	-52.07%
Jun 30, 2025	DEUTSCHE BANK AG\	0.32%	325.29K	2.11M	-9.23K	-2.76%
Jun 30, 2025	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.31%	320.22K	2.08M	296.48K	+1,249.02%
Jun 30, 2025	BANK OF NEW YORK MELLON CORP	0.3%	307.85K	2M	59.47K	+23.94%
Jun 30, 2025	Y-INTERCEPT (HONG KONG) LTD	0.27%	281.53K	1.83M	281.53K	+100.00%
Jun 30, 2025	SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC	0.26%	263.31K	1.71M	-59.56K	-18.45%
Jun 30, 2025	FISHER ASSET MANAGEMENT, LLC	0.22%	221.98K	1.44M	-53.22K	-19.34%
Jun 30, 2025	CUBIST SYSTEMATIC STRATEGIES, LLC	0.19%	193.86K	1.26M	193.86K	+100.00%
Jun 30, 2025	BRAIDWELL LP	2.12%	2.18M	14.18M	-1.36M	-38.32%
Jun 30, 2025	POLAR CAPITAL HOLDINGS PLC	2.05%	2.11M	13.71M	-240.82K	-10.25%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.66%	1.71M	11.13M	171.96K	+11.16%
Jun 30, 2025	PARKWOOD LLC	0.27%	275K	1.79M	0	0
Jun 30, 2025	SCHRODER INVESTMENT MANAGEMENT GROUP	0.17%	180.13K	1.17M	180.13K	+100.00%
Jun 30, 2025	NORGES BANK	0.16%	169K	1.1M	169K	+100.00%
Mar 31, 2025	TREXQUANT INVESTMENT LP	0.2%	204.78K	1.62M	116.81K	+132.78%
Mar 31, 2025	WOODLINE PARTNERS LP	0.21%	213.15K	1.69M	-585.77K	-73.32%
Mar 31, 2025	DAFNA CAPITAL MANAGEMENT LLC	0.71%	731.36K	5.8M	0	0
Mar 31, 2025	MARSHALL WACE, LLP	0.86%	887.18K	7.04M	-210.59K	-19.18%
Mar 31, 2025	PARKMAN HEALTHCARE PARTNERS LLC	1.02%	1.04M	8.27M	42.69K	+4.27%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	1.02%	1.05M	8.3M	1.03M	+4,997.67%
Mar 31, 2025	HUDSON BAY CAPITAL MANAGEMENT LP	1.12%	1.15M	9.12M	230.29K	+25.03%
Mar 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.14%	1.17M	9.3M	-533.02K	-31.24%
Mar 31, 2025	DIMENSIONAL FUND ADVISORS LP	1.27%	1.3M	10.33M	375.95K	+40.55%
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	1.29%	1.32M	10.47M	1.13M	+587.19%
Mar 31, 2025	FMR LLC	13.34%	13.7M	108.64M	812.98K	+6.31%
Mar 31, 2025		0.14%	139.66K	1.11M	139.66K	+100.00%
Mar 31, 2025	CITIGROUP INC	0.16%	164.68K	1.31M	8.44K	+5.40%
Mar 31, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.33%	334.99K	2.66M	0	0
Mar 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0.34%	348.44K	2.76M	104.7K	+42.96%
Mar 31, 2025	DEUTSCHE BANK AG\	0.33%	334.52K	2.65M	-24.4K	-6.80%
Mar 31, 2025	ALGERT GLOBAL LLC	0.36%	371.38K	2.95M	371.38K	+100.00%
Mar 31, 2025	PARKWOOD LLC	0.27%	275K	2.18M	0	0
Mar 31, 2025	FISHER ASSET MANAGEMENT, LLC	0.27%	275.21K	2.18M	186.08K	+208.76%
Mar 31, 2025	AQR CAPITAL MANAGEMENT LLC	0.6%	618.63K	4.91M	530.43K	+601.41%
Mar 31, 2025	MORGAN STANLEY	0.69%	709.42K	5.63M	-370.85K	-34.33%
Mar 31, 2025	CITADEL ADVISORS LLC	1.3%	1.34M	10.62M	727.71K	+119.04%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.5%	1.54M	12.22M	77.48K	+5.30%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	1.53%	1.57M	12.45M	1.1M	+232.44%
Mar 31, 2025	POLAR CAPITAL HOLDINGS PLC	2.29%	2.35M	18.64M	2.17M	+1,170.27%
Mar 31, 2025	VESTAL POINT CAPITAL, LP	2.53%	2.6M	20.6M	1.16M	+80.43%
Mar 31, 2025	BRAIDWELL LP	3.44%	3.54M	28.05M	-1.34M	-27.43%
Mar 31, 2025	PICTET ASSET MANAGEMENT HOLDING SA	3.54%	3.64M	28.83M	145.52K	+4.17%
Mar 31, 2025	FRANKLIN RESOURCES INC	3.91%	4.02M	31.87M	135.42K	+3.49%
Mar 31, 2025	ALYESKA INVESTMENT GROUP, L.P.	3.95%	4.06M	32.19M	1.55M	+61.60%
Mar 31, 2025	RA CAPITAL MANAGEMENT, L.P.	5.6%	5.76M	45.64M	0	0
Mar 31, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.27%	280.78K	2.23M	96.13K	+52.06%
Mar 31, 2025	SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC	0.31%	322.88K	2.56M	322.88K	+100.00%
Mar 31, 2025	KENNEDY CAPITAL MANAGEMENT LLC	0.32%	327.69K	2.6M	133.78K	+68.99%
Mar 31, 2025	VANGUARD GROUP INC	5.79%	5.94M	47.13M	94.32K	+1.61%
Mar 31, 2025	BLACKROCK, INC.	6.58%	6.76M	53.59M	602.09K	+9.78%
Mar 31, 2025	BANK OF NEW YORK MELLON CORP	0.24%	248.38K	1.97M	3.55K	+1.45%
Mar 31, 2025	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	2.88%	2.96M	23.48M	364.71K	+14.05%
Mar 31, 2025	STATE STREET CORP	2.64%	2.71M	21.46M	-394.98K	-12.73%
Mar 31, 2025	NORTHERN TRUST CORP	0.52%	536K	4.25M	-11.05K	-2.02%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.51%	528.15K	4.19M	-7.35K	-1.37%
Mar 31, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.12%	119.16K	944.94K	-40.25K	-25.25%
Mar 31, 2025	ESTUARY CAPITAL MANAGEMENT LP	3.24%	3.33M	26.38M	-389.93K	-10.49%
Mar 31, 2025	UBS GROUP AG	0.12%	124.18K	984.72K	59.95K	+93.34%
Mar 31, 2025	BARCLAYS PLC	0.15%	155.21K	1.23M	13.76K	+9.73%
Mar 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.16%	162K	1.28M	125.32K	+341.61%
Mar 31, 2025	STONEPINE CAPITAL MANAGEMENT, LLC	0.34%	348.82K	2.77M	113.82K	+48.43%
Mar 31, 2025	BALYASNY ASSET MANAGEMENT L.P.	0.13%	133.64K	1.06M	104.19K	+353.71%
Mar 31, 2025	HENNION & WALSH ASSET MANAGEMENT, INC.	0.13%	137.97K	1.09M	16.8K	+13.87%
Mar 31, 2025	ROYAL BANK OF CANADA	0.18%	185.73K	1.47M	53.46K	+40.42%
Mar 31, 2024	BRAIDWELL LP	2.72%	2.17M	35.91M	-2.04M	-48.44%
Mar 31, 2024	PROFUND ADVISORS LLC	0.04%	30.61K	505.71M	-8.21K	-21.14%
Mar 31, 2024	AMERICAN INTERNATIONAL GROUP, INC.	0.04%	30.88K	510.09K	-265	-0.85%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.04%	30.9K	510.47K	30.9K	+100.00%
Mar 31, 2024	INVESCO LTD.	0.04%	31.64K	522.74K	285	+0.91%
Mar 31, 2024	LEGATO CAPITAL MANAGEMENT LLC	0.04%	32.03K	529.12K	-9.89K	-23.59%
Mar 31, 2024	JUMP FINANCIAL, LLC	0.04%	32.14K	530.99K	32.14K	+100.00%
Mar 31, 2024	METLIFE INVESTMENT MANAGEMENT, LLC	0.04%	33.44K	552.48K	0	0
Mar 31, 2024	NEOS INVESTMENT MANAGEMENT LLC	0.06%	44.42K	733.87K	28.92K	+186.47%
Mar 31, 2024	WELLS FARGO & COMPANY/MN	0.06%	45.76K	755.97K	7.54K	+19.71%
Mar 31, 2024	CREDIT SUISSE AG/	0.06%	47.15K	778.9K	0	0
Mar 31, 2024	MACQUARIE GROUP LTD	0.14%	110K	1.82M	0	0
Mar 31, 2024	NORTHERN TRUST CORP	0.7%	558.15K	9.22M	-18.61K	-3.23%
Mar 31, 2024	DAFNA CAPITAL MANAGEMENT LLC	0.84%	666.46K	11.01M	-20K	-2.91%
Mar 31, 2024	PARKMAN HEALTHCARE PARTNERS LLC	0.87%	691.81K	11.43M	66.06K	+10.56%
Mar 31, 2024	ESTUARY CAPITAL MANAGEMENT LP	2.02%	1.61M	26.62M	728.24K	+82.48%
Mar 31, 2024	TIMESSQUARE CAPITAL MANAGEMENT, LLC	2.05%	1.64M	27.01M	-30.92K	-1.86%
Mar 31, 2024	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	2.21%	1.77M	29.16M	4.13K	+0.23%
Mar 31, 2024	JANUS HENDERSON GROUP PLC	2.55%	2.03M	33.57M	336.28K	+19.83%
Mar 31, 2024	DRIEHAUS CAPITAL MANAGEMENT LLC	0.9%	719.01K	11.88M	235.77K	+48.79%
Mar 31, 2024	DIMENSIONAL FUND ADVISORS LP	1.23%	981.57K	16.22M	203.66K	+26.18%
Mar 31, 2024	POLAR CAPITAL HOLDINGS PLC	1.49%	1.19M	19.58M	-200K	-14.44%
Mar 31, 2024	BOXER CAPITAL, LLC	1.49%	1.19M	19.66M	0	0
Mar 31, 2024	MAVERICK CAPITAL LTD	1.58%	1.26M	20.76M	1.26M	+100.00%
Mar 31, 2024	FIRST TURN MANAGEMENT, LLC	1.65%	1.32M	21.78M	-382.74K	-22.50%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	1.73%	1.38M	22.75M	28.14K	+2.09%
Mar 31, 2024	BLACKROCK INC.	6.31%	5.03M	83.12M	-94.64K	-1.85%
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	2.88%	2.3M	37.99M	-17K	-0.73%
Mar 31, 2024	PICTET ASSET MANAGEMENT HOLDING SA	2.98%	2.38M	39.24M	-196.43K	-7.64%
Mar 31, 2024	VIKING GLOBAL INVESTORS LP	3.21%	2.56M	42.27M	0	0
Mar 31, 2024	STATE STREET CORP	3.63%	2.89M	47.82M	-485.22K	-14.36%
Mar 31, 2024	FRANKLIN RESOURCES INC	4.77%	3.81M	62.89M	-430.01K	-10.15%
Mar 31, 2024	FMR LLC	5.52%	4.4M	72.76M	436.18K	+10.99%
Mar 31, 2024	VANGUARD GROUP INC	5.99%	4.77M	78.87M	4.74K	+0.10%
Mar 31, 2024	ATLAS VENTURE LIFE SCIENCE ADVISORS, LLC	8.06%	6.43M	106.23M	-1.18M	-15.48%
Mar 31, 2024	RA CAPITAL MANAGEMENT, L.P.	9.79%	7.81M	129.02M	0	0
Mar 31, 2024	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.2%	159K	2.63M	9K	+6.00%
Mar 31, 2024	UBS GROUP AG	0.21%	164.02K	2.71M	37.38K	+29.52%
Mar 31, 2024	LAURION CAPITAL MANAGEMENT LP	0.21%	164.98K	2.73M	0	0
Mar 31, 2024	PRUDENTIAL FINANCIAL INC	0.21%	169.52K	2.8M	169.52K	+100.00%
Mar 31, 2024	CITIGROUP INC	0.21%	171.05K	2.83M	71.13K	+71.18%
Mar 31, 2024	SIMPLIFY ASSET MANAGEMENT INC.	0.22%	175.02K	2.89M	0	0
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.22%	175.78K	2.9M	0	0
Mar 31, 2024	DEUTSCHE BANK AG\	0.22%	178.17K	2.94M	1.02K	+0.57%
Mar 31, 2024	RAFFERTY ASSET MANAGEMENT, LLC	0.24%	193.22K	3.19M	-43.12K	-18.25%
Mar 31, 2024	ALTITUDE CREST PARTNERS INC.	0.25%	195.5K	3.23M	195.5K	+100.00%
Mar 31, 2024	SAMSARA BIOCAPITAL, LLC	0.25%	196.43K	3.24M	0	0
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.27%	215.38K	3.56M	-18.82K	-8.03%
Mar 31, 2024	D. E. SHAW & CO., INC.	0.28%	224.22K	3.7M	28.73K	+14.70%
Mar 31, 2024	MORGAN STANLEY	0.29%	232.55K	3.84M	-101.89K	-30.47%
Mar 31, 2024	SCHONFELD STRATEGIC ADVISORS LLC	0.3%	237.75K	3.93M	58.81K	+32.87%
Mar 31, 2024	PROPEL BIO MANAGEMENT, LLC	0.34%	270.66K	4.47M	0	0
Mar 31, 2024	WELLINGTON MANAGEMENT GROUP LLP	0.34%	272.12K	4.5M	63.15K	+30.22%
Mar 31, 2024	WOODLINE PARTNERS LP	0.34%	272.54K	4.5M	0	0
Mar 31, 2024	CANDRIAM S.C.A.	0.36%	290.01K	4.79M	0	0
Mar 31, 2024	SUPERSTRING CAPITAL MANAGEMENT LP	0.44%	349.68K	5.78M	-29.95K	-7.89%
Mar 31, 2024	PFM HEALTH SCIENCES, LP	0.45%	355.25K	5.87M	-948.32K	-72.75%
Mar 31, 2024	NICHOLAS INVESTMENT PARTNERS, LP	0.45%	361.77K	5.98M	58.45K	+19.27%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.57%	457.65K	7.56M	4.72K	+1.04%
Mar 31, 2024	SPHERA FUNDS MANAGEMENT LTD.	0.62%	492.63K	8.14M	-20.37K	-3.97%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	2.68%	2.14M	35.31M	18.64K	+0.88%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.06%	50.37K	832.08K	9.49K	+23.22%
Mar 31, 2024	SUMMIT ROCK ADVISORS, LP	0.06%	51.5K	850.81K	51.5K	+100.00%
Mar 31, 2024	BALYASNY ASSET MANAGEMENT L.P.	0.07%	53.15K	878.07K	37.55K	+240.61%
Mar 31, 2024	LEGAL & GENERAL GROUP PLC	0.07%	53.42K	882.57M	-67	-0.13%
Mar 31, 2024	MARTINGALE ASSET MANAGEMENT L P	0.07%	53.88K	890.12K	20.14K	+59.68%
Mar 31, 2024	HENNION & WALSH ASSET MANAGEMENT, INC.	0.07%	59.29K	979.45K	1.45K	+2.50%
Mar 31, 2024	ALPS ADVISORS INC	0.08%	61.63K	1.02M	1.94K	+3.24%
Mar 31, 2024	NEW YORK STATE COMMON RETIREMENT FUND	0.08%	66.23K	1.09M	-12.07K	-15.42%
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	0.09%	68K	1.12M	16.5K	+32.04%
Mar 31, 2024	FISHER ASSET MANAGEMENT, LLC	0.09%	68.41K	1.13M	-35	-0.05%
Mar 31, 2024	JPMORGAN CHASE & CO	0.09%	71.21K	1.18M	-33.59K	-32.05%
Mar 31, 2024	RHUMBLINE ADVISERS	0.11%	89.73K	1.48M	2.29K	+2.62%
Mar 31, 2024	SWISS NATIONAL BANK	0.12%	95.4K	1.58M	0	0
Mar 31, 2024	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.12%	97.62K	1.61M	56.72K	+138.66%
Dec 31, 2023	PFM HEALTH SCIENCES, LP	1.52%	1.3M	19.03M	-921.02K	-41.40%
Dec 31, 2023	BOXER CAPITAL, LLC	1.38%	1.19M	17.37M	0	0
Dec 31, 2023	BAKER BROS. ADVISORS LP	1.16%	1M	14.6M	0	0
Dec 31, 2023	DIMENSIONAL FUND ADVISORS LP	0.91%	777.92K	11.36M	471.73K	+154.07%
Dec 31, 2023	DAFNA CAPITAL MANAGEMENT LLC	0.8%	686.46K	10.02M	100K	+17.05%
Dec 31, 2023	PARKMAN HEALTHCARE PARTNERS LLC	0.73%	625.75K	9.14M	159.34K	+34.16%
Dec 31, 2023	NORTHERN TRUST CORP	0.67%	576.75K	8.42M	24.9K	+4.51%
Dec 31, 2023	SPHERA FUNDS MANAGEMENT LTD.	0.6%	513K	7.49M	-17K	-3.21%
Dec 31, 2023	DRIEHAUS CAPITAL MANAGEMENT LLC	0.56%	483.24K	7.06M	-5.08K	-1.04%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.53%	452.93K	6.61M	5.8K	+1.30%
Dec 31, 2023	NUVEEN ASSET MANAGEMENT, LLC	0.2%	175.78K	2.57M	-249.43K	-58.66%
Dec 31, 2023	ALYESKA INVESTMENT GROUP, L.P.	0.45%	390.17K	5.7M	0	0
Dec 31, 2023	MORGAN STANLEY	0.39%	334.44K	4.88M	175.99K	+111.07%
Dec 31, 2023	DEUTSCHE BANK AG\	0.21%	177.16K	2.59M	19	+0.01%
Dec 31, 2023	SCHONFELD STRATEGIC ADVISORS LLC	0.21%	178.93K	2.61M	42.23K	+30.90%
Dec 31, 2023	BARCLAYS PLC	0.22%	185.84K	2.71M	53.96K	+40.91%
Dec 31, 2023	D. E. SHAW & CO., INC.	0.23%	195.49K	2.85M	-739	-0.38%
Dec 31, 2023	SAMSARA BIOCAPITAL, LLC	0.23%	196.43K	2.87M	0	0
Dec 31, 2023	WELLINGTON MANAGEMENT GROUP LLP	0.24%	208.97K	3.05M	208.97K	+100.00%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.27%	234.2K	3.42M	13.9K	+6.31%
Dec 31, 2023	RAFFERTY ASSET MANAGEMENT, LLC	0.28%	236.35K	3.45M	-737	-0.31%
Dec 31, 2023	PIER CAPITAL, LLC	0.3%	258.69K	3.78M	258.69K	+100.00%
Dec 31, 2023	WOODLINE PARTNERS LP	0.32%	272.54K	3.98M	0	0
Dec 31, 2023	CANDRIAM S.C.A.	0.34%	290.01K	4.23M	0	0
Dec 31, 2023	NICHOLAS INVESTMENT PARTNERS, LP	0.35%	303.32K	4.43M	-1.89M	-86.14%
Dec 31, 2023	FMR LLC	4.62%	3.97M	57.94M	-2.06M	-34.15%
Dec 31, 2023	ATLAS VENTURE LIFE SCIENCE ADVISORS, LLC	8.85%	7.61M	111.08M	0	0
Dec 31, 2023	RA CAPITAL MANAGEMENT, L.P.	9.09%	7.81M	114.02M	0	0
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.19%	159.88K	2.33M	-58.72K	-26.86%
Dec 31, 2023	LAURION CAPITAL MANAGEMENT LP	0.19%	164.98K	2.41M	164.98K	+100.00%
Dec 31, 2023	NORGES BANK	0.2%	169K	2.47M	169K	+100.00%
Dec 31, 2023	SIMPLIFY ASSET MANAGEMENT INC.	0.2%	175.02K	2.56M	0	0
Dec 31, 2023	VANGUARD GROUP INC	5.55%	4.77M	69.64M	139.99K	+3.02%
Dec 31, 2023	FRANKLIN RESOURCES INC	4.93%	4.24M	61.86M	169.46K	+4.17%
Dec 31, 2023	BRAIDWELL LP	4.9%	4.22M	61.55M	500K	+13.46%
Dec 31, 2023	STATE STREET CORP	3.93%	3.38M	49.35M	444.18K	+15.13%
Dec 31, 2023	VIKING GLOBAL INVESTORS LP	2.98%	2.56M	37.36M	0	0
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	2.7%	2.32M	33.83M	8.74K	+0.38%
Dec 31, 2023	BLACKROCK INC.	5.96%	5.13M	74.84M	437.64K	+9.33%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	2.47%	2.12M	30.94M	472.65K	+28.71%
Dec 31, 2023	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	2.05%	1.76M	25.71M	491.19K	+38.68%
Dec 31, 2023		0.31%	270.66K	3.95M	270.66K	+100.00%
Dec 31, 2023	JANUS HENDERSON GROUP PLC	1.97%	1.7M	24.76M	874.65K	+106.48%
Dec 31, 2023	TIMESSQUARE CAPITAL MANAGEMENT, LLC	1.94%	1.67M	24.33M	523.46K	+45.81%
Dec 31, 2023	POLAR CAPITAL HOLDINGS PLC	1.61%	1.39M	20.22M	-550K	-28.42%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.57%	1.35M	19.69M	55.71K	+4.31%

Insiders

Among the DAWN insiders holding of 16.94% of the stake in company, CANAAN XI L.P., 10 percent owner, holds the largest shares of 8.46M. BLACKMAN SAMUEL C., HEAD OF R&D, is the second largest DAWN insider with ownership of 1.03M shares. AI DAY1 LLC, 10 percent owner, stands third with possession of 827.59K shares of that stake.

Insiders	Designation	Shares Held
CANAAN XI L.P.	10 percent owner	8.46M
BLACKMAN SAMUEL C.	HEAD OF R&D	1.03M
AI DAY1 LLC	10 percent owner	827.59K
GRANT PAPANEK JULIE	director	439.36K
GRANT JULIE PAPANEK	director	330K
YORK CHARLES N II	COO and CFO	312.03K
BENDER JEREMY	CHIEF EXECUTIVE OFFICER	204.6K
DUBOW ADAM	Gen Counsel & Secretary	72.69K
MERENDINO LAUREN	Chief Commercial Officer	60.16K
RAMASASTRY SAIRA	director	40.49K
VASCONCELLES MICHAEL	Head of Research and Dev.	4.4K

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Feb 17, 2026	MERENDINO LAUREN	SALE	11.60	5.81K	67.45K	60.16K
Feb 17, 2026	DUBOW ADAM	SALE	11.60	6.4K	74.19K	72.69K
Feb 17, 2026	YORK CHARLES N II	SALE	11.60	6.07K	70.36K	312.03K
Feb 17, 2026	BENDER JEREMY	SALE	11.60	15.46K	179.34K	204.6K
Feb 17, 2026	VASCONCELLES MICHAEL	SALE	11.60	2.73K	31.65K	4.4K
Nov 17, 2025	DUBOW ADAM	SALE	8.91	4.32K	38.5K	62.63K
Nov 17, 2025	BENDER JEREMY	SALE	8.91	15.89K	141.69K	177.17K
Nov 17, 2025	MERENDINO LAUREN	SALE	8.91	3.73K	33.22K	50.81K
Nov 17, 2025	YORK CHARLES N II	SALE	8.91	4.06K	36.21K	294.72K
Aug 18, 2025	BENDER JEREMY	SALE	6.77	16.06K	108.67K	161.37K
Aug 18, 2025	YORK CHARLES N II	SALE	6.77	4.11K	27.79K	278K
Aug 18, 2025	MERENDINO LAUREN	SALE	6.77	3.77K	25.48K	41.93K
Aug 18, 2025	DUBOW ADAM	SALE	6.77	4.37K	29.54K	54.86K
May 16, 2025	MERENDINO LAUREN	SALE	6.26	3.93K	24.57K	35.16K
May 16, 2025	BENDER JEREMY	SALE	6.26	13.96K	87.39K	145.74K
May 16, 2025	YORK CHARLES N II	SALE	6.26	4.28K	26.8K	265.23K
May 16, 2025	DUBOW ADAM	SALE	6.26	4.55K	28.49K	47.14K
Feb 18, 2025	BENDER JEREMY	SALE	11.96	12.05K	144.13K	128.02K
Feb 18, 2025	DUBOW ADAM	SALE	11.96	4.65K	55.58K	39.6K
Feb 18, 2025	YORK CHARLES N II	SALE	11.96	4.37K	52.28K	252.64K
Dec 10, 2024	BLACKMAN SAMUEL C.	SALE	13.31	30K	399.34K	1.03M
Nov 18, 2024	DUBOW ADAM	SALE	13.21	3.17K	41.81K	32.16K
Nov 18, 2024	YORK CHARLES N II	SALE	13.21	2.6K	34.37K	240.13K
Nov 18, 2024	BENDER JEREMY	SALE	13.21	10.55K	139.42K	108.38K
Nov 18, 2024	BLACKMAN SAMUEL C.	SALE	13.21	2.21K	29.14K	1.06M
Nov 11, 2024	BLACKMAN SAMUEL C.	SALE	16.10	10K	160.99K	1.06M
Nov 08, 2024	BLACKMAN SAMUEL C.	SALE	16.17	18.26K	295.23K	1.07M
Nov 07, 2024	BLACKMAN SAMUEL C.	SALE	16.03	11.25K	180.29K	1.09M
Oct 31, 2024	BLACKMAN SAMUEL C.	SALE	16.02	500	8.01K	1.1M
Sep 10, 2024	BLACKMAN SAMUEL C.	SALE	14.22	30K	426.68K	1.1M
Aug 16, 2024	DUBOW ADAM	SALE	14.00	3.2K	44.83K	26.93K
Aug 16, 2024	BENDER JEREMY	SALE	14.00	10.68K	149.52K	98.93K
Aug 16, 2024	BLACKMAN SAMUEL C.	SALE	14.00	2.23K	31.25K	1.13M
Aug 16, 2024	YORK CHARLES N II	SALE	14.00	2.63K	36.86K	232.49K
Aug 01, 2024	AI DAY1 LLC	PURCHASE	0.00	827.59K	82.76	827.59K
Jul 16, 2024	BLACKMAN SAMUEL C.	SALE	16.01	20K	320.23K	1.12M
Jun 21, 2024	RAMASASTRY SAIRA	SALE	13.19	10K	131.88K	40.49K
Jun 10, 2024	BLACKMAN SAMUEL C.	SALE	12.62	30K	378.59K	1.14M
May 16, 2024	BLACKMAN SAMUEL C.	SALE	16.08	2.27K	36.45K	1.17M
May 16, 2024	YORK CHARLES N II	SALE	16.08	2.68K	43.01K	224.87K
May 16, 2024	BENDER JEREMY	SALE	16.08	7.87K	126.59K	654.73K
May 16, 2024	DUBOW ADAM	SALE	16.08	3.25K	52.3K	21.73K
May 10, 2024	BLACKMAN SAMUEL C.	SALE	16.37	10K	163.74K	1.16M
May 03, 2024	BENDER JEREMY	SALE	17.85	9.15K	163.42K	642.6K
May 03, 2024	YORK CHARLES N II	SALE	17.85	8.08K	144.21K	217.29K
May 02, 2024	BENDER JEREMY	SALE	17.94	6	107.63	651.76K
May 02, 2024	YORK CHARLES N II	SALE	17.90	200	3.58K	225.37K
May 01, 2024	BENDER JEREMY	SALE	17.88	70.05K	1.25M	651.76K
May 01, 2024	YORK CHARLES N II	SALE	17.89	52.18K	933.4K	225.57K
Apr 18, 2024	BLACKMAN SAMUEL C.	SALE	16.02	10K	160.16K	1.17M
Mar 25, 2024	BLACKMAN SAMUEL C.	SALE	16.01	10K	160.06K	1.18M
Mar 11, 2024	BLACKMAN SAMUEL C.	SALE	15.24	30K	457.31K	1.19M
Feb 27, 2024	BLACKMAN SAMUEL C.	SALE	16.11	20K	322.17K	1.22M
Feb 16, 2024	DUBOW ADAM	SALE	15.25	3.24K	49.43K	16.59K
Feb 16, 2024	BENDER JEREMY	SALE	15.25	7.62K	116.11K	721.81K
Feb 16, 2024	YORK CHARLES N II	SALE	15.25	2.67K	40.65K	277.75K
Feb 16, 2024	BLACKMAN SAMUEL C.	SALE	15.25	2.26K	34.43K	1.24M
Nov 16, 2023	YORK CHARLES N II	SALE	11.69	956	11.18K	270.17K
Nov 16, 2023	BLACKMAN SAMUEL C.	SALE	11.69	709	8.29K	1.24M
Nov 16, 2023	DUBOW ADAM	SALE	11.69	5.31K	62.11K	11.43K
Nov 16, 2023	BENDER JEREMY	SALE	11.69	3.11K	36.32K	709.43K
Oct 20, 2023	AI DAY1 LLC	PURCHASE	9.97	111.39K	1.11M	12.93M
Oct 19, 2023	AI DAY1 LLC	PURCHASE	10.06	384.4K	3.87M	12.82M
Oct 18, 2023	AI DAY1 LLC	PURCHASE	10.21	979.67K	10M	12.43M
Aug 17, 2023	BENDER JEREMY	SALE	13.86	3K	41.52K	704.22K
Aug 17, 2023	YORK CHARLES N II	SALE	13.86	922	12.78K	267.5K
Aug 17, 2023	BLACKMAN SAMUEL C.	SALE	13.86	668	9.26K	1.24M
Jun 09, 2023	AI DAY1 LLC	PURCHASE	13.00	769.23K	10M	11.45M
Jun 05, 2023	BLACKMAN SAMUEL C.	SALE	16.00	1.23K	19.66K	1.23M
May 16, 2023	BENDER JEREMY	SALE	13.12	3.1K	40.73K	1.18M
May 16, 2023	YORK CHARLES N II	SALE	13.12	955	12.53K	264.8K
May 16, 2023	BLACKMAN SAMUEL C.	SALE	13.12	692	9.08K	1.24M
Mar 10, 2023	BLACKMAN SAMUEL C.	SALE	18.05	10K	180.48K	1.23M
Mar 07, 2023	BENDER JEREMY	SALE	20.01	12.5K	250.11K	1.17M
Mar 01, 2023	GRANT JULIE PAPANEK	SALE	18.61	25K	465.3K	330K
Feb 17, 2023	YORK CHARLES N II	SALE	20.03	9.38K	187.79K	262.13K
Feb 16, 2023	BENDER JEREMY	SALE	19.57	3.02K	59.15K	1.19M
Feb 16, 2023	BLACKMAN SAMUEL C.	SALE	19.57	674	13.19K	1.24M
Feb 16, 2023	YORK CHARLES N II	SALE	19.57	930	18.2K	271.51K
Feb 10, 2023	BLACKMAN SAMUEL C.	SALE	20.07	10K	200.66K	1.24M
Feb 01, 2023	GRANT JULIE PAPANEK	SALE	21.69	1.11K	23.99K	355K
Jan 23, 2023	BENDER JEREMY	SALE	22.00	12.5K	274.99K	1.18M
Jan 20, 2023	YORK CHARLES N II	SALE	22.75	10K	227.52K	268.81K
Jan 10, 2023	BLACKMAN SAMUEL C.	SALE	23.20	2.5K	58.01K	1.25M
Jan 03, 2023	GRANT JULIE PAPANEK	SALE	21.31	7.61K	162.17K	380K
Dec 21, 2022	BENDER JEREMY	SALE	20.32	12.5K	253.97K	1.19M
Dec 20, 2022	YORK CHARLES N II	SALE	20.07	10K	200.65K	276.5K
Dec 08, 2022	GRANT JULIE PAPANEK	SALE	22.08	4.36K	96.21K	405K
Dec 02, 2022	GRANT JULIE PAPANEK	SALE	21.55	5K	107.73K	409.36K
Dec 01, 2022	BLACKMAN SAMUEL C.	SALE	22.16	900	19.94K	1.26M
Dec 01, 2022	GRANT JULIE PAPANEK	SALE	22.34	240	5.36K	414.36K
Nov 21, 2022	BENDER JEREMY	SALE	21.38	400	8.55K	1.2M
Nov 21, 2022	YORK CHARLES N II	SALE	21.39	300	6.42K	286.5K
Nov 16, 2022	BLACKMAN SAMUEL C.	SALE	21.46	377	8.09K	1.27M
Nov 16, 2022	YORK CHARLES N II	SALE	21.46	430	9.23K	296.5K
Nov 16, 2022	BENDER JEREMY	SALE	21.46	1.51K	32.47K	1.22M
Nov 02, 2022	GRANT JULIE PAPANEK	SALE	20.01	5K	100.07K	419.36K
Nov 01, 2022	BLACKMAN SAMUEL C.	SALE	20.00	10K	200.05K	1.27M
Nov 01, 2022	GRANT JULIE PAPANEK	SALE	20.04	5K	100.21K	424.36K
Nov 01, 2022	YORK CHARLES N II	SALE	20.03	10K	200.31K	294.4K
Nov 01, 2022	BENDER JEREMY	SALE	20.03	12.5K	250.36K	1.22M
Oct 04, 2022	GRANT JULIE PAPANEK	SALE	20.00	5K	100K	429.36K
Oct 03, 2022	YORK CHARLES N II	SALE	20.05	10K	200.47K	304.4K
Oct 03, 2022	BLACKMAN SAMUEL C.	SALE	19.99	10K	199.85K	1.28M
Oct 03, 2022	GRANT JULIE PAPANEK	SALE	20.06	5K	100.32K	434.36K
Oct 03, 2022	BENDER JEREMY	SALE	20.05	12.5K	250.65K	1.23M
Sep 21, 2022	GRANT JULIE PAPANEK	SALE	19.29	6.11K	117.78K	8.46M
Sep 21, 2022	CANAAN XI L.P.	SALE	19.29	6.11K	117.78K	8.46M
Sep 20, 2022	CANAAN XI L.P.	SALE	20.10	2.27K	45.55K	9.08M
Sep 20, 2022	GRANT JULIE PAPANEK	SALE	20.10	2.27K	45.55K	9.08M
Sep 19, 2022	CANAAN XI L.P.	SALE	20.57	76.73K	1.58M	9.23M
Sep 19, 2022	GRANT JULIE PAPANEK	SALE	20.57	76.73K	1.58M	9.23M
Sep 16, 2022	GRANT JULIE PAPANEK	SALE	22.04	3.72K	82.03K	9.3M
Sep 16, 2022	CANAAN XI L.P.	SALE	22.04	3.72K	82.03K	9.3M
Sep 15, 2022	CANAAN XI L.P.	SALE	22.79	47.97K	1.09M	9.42M
Sep 15, 2022	GRANT JULIE PAPANEK	SALE	23.73	3.31K	78.64K	9.42M
Sep 14, 2022	CANAAN XI L.P.	SALE	23.68	105.73K	2.5M	9.47M
Sep 14, 2022	GRANT JULIE PAPANEK	SALE	24.29	384	9.33K	9.47M
Sep 13, 2022	GRANT JULIE PAPANEK	SALE	25.01	1K	25.09K	9.58M
Sep 13, 2022	CANAAN XI L.P.	SALE	25.01	1K	25.09K	9.58M
Sep 02, 2022	GRANT PAPANEK JULIE	SALE	23.82	5K	119.11K	439.36K
Sep 01, 2022	BENDER JEREMY	SALE	23.79	1.86K	44.23K	1.24M
Sep 01, 2022	BLACKMAN SAMUEL C.	SALE	23.79	1.59K	37.81K	1.29M
Sep 01, 2022	GRANT PAPANEK JULIE	SALE	23.21	4.47K	103.72K	444.89K
Sep 01, 2022	YORK CHARLES N II	SALE	23.80	1.39K	33.18K	314.4K
Aug 15, 2022	BLACKMAN SAMUEL C.	SALE	24.31	941	22.88K	1.3M
Aug 15, 2022	YORK CHARLES N II	SALE	24.31	1.09K	26.47K	324.4K
Aug 15, 2022	BENDER JEREMY	SALE	24.31	4K	97.31K	1.25M
Aug 04, 2022	YORK CHARLES N II	SALE	20.05	10K	200.54K	321.37K
Aug 04, 2022	GRANT PAPANEK JULIE	SALE	20.00	5K	100K	454.36K
Aug 04, 2022	BENDER JEREMY	SALE	20.00	12.5K	250.02K	1.25M
Aug 01, 2022	BLACKMAN SAMUEL C.	SALE	16.88	10K	168.81K	1.3M
Jul 18, 2022	YORK CHARLES N II	SALE	20.00	2.5K	50K	331.37K
Jul 18, 2022	BENDER JEREMY	SALE	20.00	2.6K	52K	1.26M
Jul 18, 2022	GRANT PAPANEK JULIE	SALE	20.00	2.6K	52K	459.36K
Jul 05, 2022	GRANT PAPANEK JULIE	SALE	20.00	800	16K	463.2K
Jul 01, 2022	GRANT PAPANEK JULIE	SALE	20.00	1K	20K	464K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES64.46K9

NET SHARES-64.46K9

SHARES HELD1.24M9

% NET SHARES-105.2%0%

Frequently Asked Questions