How many institutions own CRVS stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own CRVS shares is 122, representing 56.22% of the company's common stock.

Who are the major shareholders selling Corvus Pharmaceuticals, Inc. stock?

LOGOS GLOBAL MANAGEMENT LP, in the last quarter, reduced its stake in CRVS by -10% restricting it's holding to 450 thousand shares of worth nearly $6.58M. SUSQUEHANNA INTERNATIONAL GROUP, LLP also lessened -28.36% of the CRVS shares from its portfolio, reducing its holding to 186.4 thousand shares of worth $2.73M. BIOIMPACT CAPITAL LLC also shunned CRVS shares holding by -38.96% last quarter which brought its holding to 1.67 million shares worth $24.50M.

Investors who are buying CRVS stock?

As per its latest 13F filing, SG AMERICAS SECURITIES, LLC increased its stake in CRVS by 76.91% in the last quarter. The institutional holder raised its holding to 35.42 thousand shares having worth more than $518.00K. CITADEL ADVISORS LLC also added 15.66% more shares of CRVS to its portfolio, raising its holding to 202.4 thousand shares of worth $2.96M. NEXTECH INVEST, LTD. also increased its CRVS shares holding by 100% which brought its holding to 450 thousand shares worth $6.58M.

CRVS's major insiders: who are they?

The insider with the most stakes in CRVS is ORBIMED ADVISORS LLC , at the company. Additionally, CRVS stock is highly held by Thompson Peter A. and 10 percent owner Novo A/S among others.

Did an insider recently sell CRVS stock?

Company executives, directors, and other insiders own 3.96% percent of Corvus Pharmaceuticals, Inc.'s stock. Within the last six months, there have been 0 transaction(s) in which CRVS insiders have sold stock, totaling 0 shares. Insiders that have sold shares include ORBIMED ADVISORS LLC, THOMPSON PETER A., and ECOR1 CAPITAL, LLC.

Which insider recently purchased CRVS stock?

There have been 0 transaction(s) during the past 6-months in which Corvus Pharmaceuticals, Inc. insiders have bought stock, totalling 0 shares

How much of CRVS does insiders own?

Around 0 Corvus Pharmaceuticals, Inc. shares are held by insiders, which represents about 3.96% of CRVS stock.

Who is the insider with the largest stake?

CRVS , ORBIMED ADVISORS LLC holds the largest portfolio of the company's shares. CRVS shares owned by ORBIMED total nearly 7.17 million.

Which institution holds the most shares in CRVS?

SG AMERICAS SECURITIES, LLC is the largest institutional owner in CRVS which holds 35.42 thousand shares worth $518.00K or 0.04% of the total CRVS shares outstanding followed by CITADEL ADVISORS LLC with ownership of 202.4 thousand shares representing 0.26% of the CRVS ownership. LOGOS GLOBAL MANAGEMENT LP is the third largest stakeholder with 450 thousand shares or 0.57% of the ownership worth more than $6.58M.

Is Corvus Pharmaceuticals, Inc. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the CRVS is concerned, it is a stock which is optionable.

Is there a short position on CRVS's shares?

Number of CRVS shares short is 9.29M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding CRVS shares are there?

As of today, 74.51M shares of CRVS are outstanding.

Is there many float in CRVS stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, CRVS has 57.36M shares in float.

CRVS short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for CRVS is 19.81.

Corvus Pharmaceuticals (CRVS) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares12.47

Short Percent Of Float15.78

Shares Outstanding74.51M

Shares Float57.36M

Shares Short9.29M

Short Ratio19.81

15.78%

Short % of Float

12.47%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

3.96% Percentage of Shares held by All Insiders

56.22% Percentage of Shares held by All Institutions

58.54% Percentage of Float held by Institutions

122

Number of Institutions Holding Shares

Institutional Ownership

About 56.22% of CRVS shares are held by financial institutions. SG AMERICAS SECURITIES, LLC is the top corporate investor, holding 35.42K shares valued at $518.00K. A 0.04% stake in Corvus Pharmaceuticals, Inc. is owned by the company. CITADEL ADVISORS LLC owns 202.4K shares valued at $2.96M, which translates its holding of 0.26% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Mar 31, 2026	SG AMERICAS SECURITIES, LLC	0.04%	35.42K	518K	15.4K	+76.91%
Mar 31, 2026	CITADEL ADVISORS LLC	0.26%	202.4K	2.96M	27.4K	+15.66%
Mar 31, 2026	LOGOS GLOBAL MANAGEMENT LP	0.57%	450K	6.58M	-50K	-10.00%
Mar 31, 2026	NEXTECH INVEST, LTD.	0.57%	450K	6.58M	450K	+100.00%
Mar 31, 2026	RA CAPITAL MANAGEMENT, L.P.	0.57%	450K	6.58M	450K	+100.00%
Mar 31, 2026	TWO SIGMA INVESTMENTS, LP	0.68%	539.87K	7.9M	396.27K	+275.96%
Mar 31, 2026	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.24%	186.4K	2.73M	-73.8K	-28.36%
Mar 31, 2026	MARSHALL WACE, LLP	0.69%	548.29K	8.02M	332.04K	+153.54%
Mar 31, 2026	EVENTIDE ASSET MANAGEMENT, LLC	0.7%	550K	8.05M	550K	+100.00%
Mar 31, 2026	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.95%	750K	10.97M	750K	+100.00%
Mar 31, 2026	MILLENNIUM MANAGEMENT LLC	1.1%	866.36K	12.67M	177.59K	+25.78%
Mar 31, 2026	CATALIO CAPITAL MANAGEMENT, LP	1.13%	891.93K	13.05M	891.93K	+100.00%
Mar 31, 2026	POLAR CAPITAL HOLDINGS PLC	1.36%	1.07M	15.66M	1.07M	+100.00%
Mar 31, 2026	BOXER CAPITAL MANAGEMENT, LLC	1.39%	1.1M	16.09M	1.1M	+100.00%
Mar 31, 2026	HOOD RIVER CAPITAL MANAGEMENT LLC	1.69%	1.34M	19.53M	1.34M	+100.00%
Mar 31, 2026	GOLDMAN SACHS GROUP INC	1.95%	1.54M	22.54M	987.48K	+178.46%
Mar 31, 2026	BIOIMPACT CAPITAL LLC	2.12%	1.67M	24.5M	-1.07M	-38.96%
Mar 31, 2026	GEODE CAPITAL MANAGEMENT, LLC	2.17%	1.71M	25.06M	239.72K	+16.27%
Mar 31, 2026	BRAIDWELL LP	2.22%	1.75M	25.64M	1.75M	+100.00%
Mar 31, 2026	FORESITE CAPITAL MANAGEMENT VI LLC	2.32%	1.83M	26.79M	450K	+32.58%
Mar 31, 2026	COMMODORE CAPITAL LP	2.86%	2.26M	33.05M	2.26M	+100.00%
Mar 31, 2026	PERCEPTIVE ADVISORS LLC	2.9%	2.29M	33.54M	1.6M	+231.07%
Mar 31, 2026	WELLINGTON MANAGEMENT GROUP LLP	2.94%	2.32M	33.92M	2M	+636.78%
Mar 31, 2026	DEEP TRACK CAPITAL, LP	3.16%	2.49M	36.45M	2.49M	+100.00%
Mar 31, 2026	MORGAN STANLEY	3.16%	2.5M	36.56M	-1.07M	-29.96%
Mar 31, 2026	VIVO CAPITAL, LLC	3.55%	2.81M	41.05M	571.25K	+25.56%
Mar 31, 2026	PRICE T ROWE ASSOCIATES INC /MD/	3.69%	2.92M	42.68M	2.88M	+8,453.88%
Mar 31, 2026	ADAMS STREET PARTNERS LLC	4.15%	3.28M	47.92M	0	0
Mar 31, 2026	STATE STREET CORP	4.52%	3.57M	52.17M	777.77K	+27.89%
Mar 31, 2026	ORBIMED ADVISORS LLC	9.07%	7.17M	104.82M	0	0
Mar 31, 2026	METLIFE INVESTMENT MANAGEMENT, LLC	0.04%	33.1K	484.25K	2.32K	+7.53%
Mar 31, 2026	AVITY INVESTMENT MANAGEMENT INC.	0.04%	33.2K	485.72K	520	+1.59%
Mar 31, 2026	SIMPLEX TRADING, LLC	0.04%	34.72K	508M	34.72K	+100.00%
Mar 31, 2026	INVESCO LTD.	0.05%	38.21K	559.04K	-5.37K	-12.32%
Mar 31, 2026	FRANKLIN RESOURCES INC	0.05%	39.08K	571.76K	39.08K	+100.00%
Mar 31, 2026	MASSACHUSETTS FINANCIAL SERVICES CO /MA/	0.05%	41.42K	605.92K	41.42K	+100.00%
Mar 31, 2026	CREATIVE PLANNING	0.05%	43.03K	629.56K	3.85K	+9.84%
Mar 31, 2026	JANE STREET GROUP, LLC	0.28%	217.8K	3.19M	179.1K	+462.79%
Mar 31, 2026	VANGUARD GLOBAL ADVISERS, LLC	0.06%	47.69K	697.68K	47.69K	+100.00%
Mar 31, 2026	HIKARI POWER LTD	0.06%	49.96K	731K	0	0
Mar 31, 2026	SEVEN GRAND MANAGERS, LLC	0.06%	50K	731.5K	50K	+100.00%
Mar 31, 2026	PROFUND ADVISORS LLC	0.06%	50.24K	734.94K	13.17K	+35.54%
Mar 31, 2026	DEUTSCHE BANK AG\	0.07%	54.48K	797.03K	-1.56K	-2.78%
Mar 31, 2026	SEI INVESTMENTS CO	0.08%	60.85K	890.21K	60.85K	+100.00%
Mar 31, 2026	PERSISTENT ASSET PARTNERS LTD	0.08%	62.05K	907.81K	62.05K	+100.00%
Mar 31, 2026	JACKSON SQUARE CAPITAL, LLC	0.08%	63.77K	933K	0	0
Mar 31, 2026	ALPS ADVISORS INC	0.09%	68.19K	997.68K	6.88K	+11.21%
Mar 31, 2026	ACADIAN ASSET MANAGEMENT LLC	0.09%	69.15K	1.01M	69.15K	+100.00%
Mar 31, 2026	TOWERVIEW LLC	0.09%	70K	1.02M	-70K	-50.00%
Mar 31, 2026	RHUMBLINE ADVISERS	0.1%	76.51K	1.12M	5.79K	+8.18%
Mar 31, 2026	RENAISSANCE TECHNOLOGIES LLC	0.1%	81.31K	1.19M	81.31K	+100.00%
Mar 31, 2026	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.11%	83.91K	1.23M	55.79K	+198.42%
Mar 31, 2026	PROPEL BIO MANAGEMENT, LLC	0.11%	85.79K	1.25M	85.79K	+100.00%
Mar 31, 2026	VOYA INVESTMENT MANAGEMENT LLC	0.13%	99.63K	1.46M	71.97K	+260.19%
Mar 31, 2026	RAYMOND JAMES FINANCIAL INC	0.13%	99.88K	1.46M	-21.27K	-17.56%
Mar 31, 2026	F/M INVESTMENTS LLC	0.13%	100.03K	1.46M	100.03K	+100.00%
Mar 31, 2026	TEMA ETFS LLC	0.14%	107.78K	1.58M	28.08K	+35.23%
Mar 31, 2026	AVIDITY PARTNERS MANAGEMENT LP	0.15%	115K	1.75M	115K	+100.00%
Mar 31, 2026	TD ASSET MANAGEMENT INC	0.16%	123.74K	1.81M	123.74K	+100.00%
Mar 31, 2026	EAM INVESTORS, LLC	0.17%	138.15K	2.02M	138.15K	+100.00%
Mar 31, 2026	JPMORGAN CHASE & CO	0.18%	145.16K	1.95M	114.5K	+373.52%
Mar 31, 2026	JUMP FINANCIAL, LLC	0.19%	147.85K	2.16M	147.85K	+100.00%
Mar 31, 2026	NUVEEN, LLC	0.19%	149.13K	2.18M	81.06K	+119.10%
Mar 31, 2026	POLYMER CAPITAL MANAGEMENT (HK) LTD	0.23%	183.19K	2.68M	183.19K	+100.00%
Mar 31, 2026	BANK OF NEW YORK MELLON CORP	0.23%	185.35K	2.71M	53.72K	+40.81%
Mar 31, 2026	UBS GROUP AG	0.37%	289.11K	4.23M	77.11K	+36.37%
Mar 31, 2026	EMERALD MUTUAL FUND ADVISERS TRUST	0.58%	459.25K	6.72M	459.25K	+100.00%
Mar 31, 2026	VANGUARD FIDUCIARY TRUST CO	0.64%	504.63K	7.38M	504.63K	+100.00%
Mar 31, 2026	NORTHERN TRUST CORP	0.64%	506.1K	7.4M	76.33K	+17.76%
Mar 31, 2026	BLUE OWL CAPITAL HOLDINGS LP	0.69%	545K	7.97M	545K	+100.00%
Mar 31, 2026	DCF ADVISERS, LLC	0.81%	637.5K	9.33M	-91.5K	-12.55%
Mar 31, 2026	EMERALD ADVISERS, LLC	0.87%	686.22K	10.04M	686.22K	+100.00%
Mar 31, 2026		0.29%	226.84K	3.32M	226.84K	+100.00%
Mar 31, 2026	BLACKROCK, INC.	7.8%	6.16M	90.13M	1.1M	+21.84%
Mar 31, 2026	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.24%	188.13K	2.75M	16.96K	+9.91%
Mar 31, 2026	BARCLAYS PLC	0.31%	243.78K	3.57M	-150.99K	-38.25%
Mar 31, 2026	DIADEMA PARTNERS LP	0.31%	244.81K	3.58M	244.81K	+100.00%
Mar 31, 2026	SPHERA FUNDS MANAGEMENT LTD.	0.31%	247.96K	3.63M	-159.75K	-39.18%
Mar 31, 2026	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.35%	278.01K	4.07M	278.01K	+100.00%
Dec 31, 2025	TEMA ETFS LLC	0.1%	79.7K	613.68K	20.5K	+34.62%
Dec 31, 2025	STATE STREET CORP	3.37%	2.79M	21.47M	1.78M	+177.07%
Dec 31, 2025	BLACKROCK, INC.	6.1%	5.06M	38.93M	345.92K	+7.34%
Dec 31, 2025	ADAMS STREET PARTNERS LLC	3.95%	3.28M	25.22M	0	0
Dec 31, 2025	MORGAN STANLEY	4.31%	3.57M	27.47M	2.95M	+478.06%
Dec 31, 2025	VANGUARD GROUP INC	4.68%	3.87M	29.83M	401.56K	+11.57%
Dec 31, 2025	CITADEL ADVISORS LLC	0.11%	93.8K	722.26K	45.6K	+94.61%
Dec 31, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.12%	99.72K	767.88K	99.72K	+100.00%
Dec 31, 2025	SQUAREPOINT OPS LLC	0.13%	104.82K	807.11K	104.82K	+100.00%
Dec 31, 2025	RAYMOND JAMES FINANCIAL INC	0.15%	121.16K	932.91K	-3.34K	-2.68%
Dec 31, 2025	BANK OF NEW YORK MELLON CORP	0.16%	131.63K	1.01M	5.1K	+4.03%
Dec 31, 2025	TOWERVIEW LLC	0.17%	140K	1.08M	-30K	-17.65%
Dec 31, 2025	FRED ALGER MANAGEMENT, LLC	0.17%	144.38K	1.11M	144.38K	+100.00%
Dec 31, 2025	MARSHALL WACE, LLP	0.26%	216.25K	1.67M	216.25K	+100.00%
Dec 31, 2025	GOLDMAN SACHS GROUP INC	0.67%	553.33K	4.26M	107.66K	+24.16%
Dec 31, 2025	MILLENNIUM MANAGEMENT LLC	0.83%	688.77K	5.3M	688.77K	+100.00%
Dec 31, 2025	PERCEPTIVE ADVISORS LLC	0.84%	692.44K	5.33M	-746.15K	-51.87%
Dec 31, 2025	DCF ADVISERS, LLC	0.88%	729K	5.61M	729K	+100.00%
Dec 31, 2025	FORESITE CAPITAL MANAGEMENT VI LLC	1.67%	1.38M	10.64M	-350K	-20.22%
Dec 31, 2025	POINT72 ASSET MANAGEMENT, L.P.	3.47%	2.88M	22.14M	-3.58M	-55.46%
Dec 31, 2025	ORBIMED ADVISORS LLC	8.65%	7.17M	55.17M	0	0
Dec 31, 2025	ARGENT ADVISORS, INC.	0.04%	30K	231K	0	0
Dec 31, 2025	JPMORGAN CHASE & CO	0.04%	30.66K	236.04K	-1.58K	-4.89%
Dec 31, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.04%	30.78K	237.02K	-2.81K	-8.37%
Dec 31, 2025	VIRTUS INVESTMENT ADVISERS, INC.	0.04%	31.78K	244.73K	4.95K	+18.43%
Dec 31, 2025	AVITY INVESTMENT MANAGEMENT INC.	0.04%	32.68K	251.64K	0	0
Dec 31, 2025	PROFUND ADVISORS LLC	0.04%	37.06K	285.39K	37.06K	+100.00%
Dec 31, 2025	JANE STREET GROUP, LLC	0.46%	378.3K	2.91M	310.23K	+455.78%
Dec 31, 2025	ANCORA ADVISORS, LLC	0.06%	47.67K	367.04K	377	+0.80%
Dec 31, 2025	HIKARI POWER LTD	0.06%	49.96K	385K	0	0
Dec 31, 2025	DEUTSCHE BANK AG\	0.07%	56.04K	431.5K	2.4K	+4.47%
Dec 31, 2025	ALPS ADVISORS INC	0.07%	61.32K	472.15K	61.32K	+100.00%
Dec 31, 2025	WELLS FARGO & COMPANY/MN	0.08%	62.62K	482.2K	26.23K	+72.06%
Dec 31, 2025	TWO SIGMA INVESTMENTS, LP	0.17%	143.6K	1.11M	-59.76K	-29.39%
Dec 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.31%	260.2K	2M	216.1K	+490.02%
Dec 31, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.02%	17.5K	134.73K	-1.23K	-6.56%
Dec 31, 2025	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.02%	18.17K	139.9K	5.11K	+39.11%
Dec 31, 2025	ADVISOR GROUP HOLDINGS, INC.	0.08%	67.99K	523.55K	1	0.00%
Dec 31, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.02%	18.8K	144.76K	0	0
Dec 31, 2025	COMMERCE BANK	0.02%	20K	154K	0	0
Dec 31, 2025	SG AMERICAS SECURITIES, LLC	0.02%	20.02K	154K	20.02K	+100.00%
Dec 31, 2025	VERITION FUND MANAGEMENT LLC	0.03%	21.38K	164.64K	21.38K	+100.00%
Dec 31, 2025	THREE BRIDGE WEALTH ADVISORS, LLC	0.03%	22.37K	172.26K	0	0
Dec 31, 2025	DRW SECURITIES, LLC	0.03%	23.38K	180.06K	23.38K	+100.00%
Dec 31, 2025	PALUMBO WEALTH MANAGEMENT LLC	0.03%	26.26K	202.16K	2.64K	+11.18%
Dec 31, 2025	JACKSON SQUARE CAPITAL, LLC	0.08%	63.77K	491.05K	0	0
Dec 31, 2025	D. E. SHAW & CO., INC.	0.08%	64.92K	499.85K	39.34K	+153.82%
Dec 31, 2025	NUVEEN, LLC	0.08%	68.06K	524.09K	0	0
Dec 31, 2025	RHUMBLINE ADVISERS	0.09%	70.73K	544.59K	-11.86K	-14.36%
Dec 31, 2025	NEOS INVESTMENT MANAGEMENT LLC	0.1%	80.89K	622.88K	21.69K	+36.64%
Dec 31, 2025	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.1%	86.72K	667.74K	86.72K	+100.00%
Dec 31, 2025	BANK OF AMERICA CORP /DE/	0.29%	236.5K	1.82M	84.53K	+55.62%
Dec 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.38%	314.68K	2.42M	134.51K	+74.65%
Dec 31, 2025	BARCLAYS PLC	0.48%	394.77K	3.04M	85.61K	+27.69%
Dec 31, 2025	UBS GROUP AG	0.26%	212.01K	1.63M	49.93K	+30.81%
Dec 31, 2025	CAPTION MANAGEMENT, LLC	0.13%	105.9K	815.43K	105.9K	+100.00%
Dec 31, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.14%	114.5K	881.65K	114.5K	+100.00%
Dec 31, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.49%	407.71K	3.14M	0	0
Dec 31, 2025	NORTHERN TRUST CORP	0.52%	429.77K	3.31M	-36.72K	-7.87%
Dec 31, 2025	RTW INVESTMENTS, LP	0.54%	447.61K	3.45M	-2.23M	-83.30%
Dec 31, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	0.56%	465.88K	3.59M	465.88K	+100.00%
Dec 31, 2025	LOGOS GLOBAL MANAGEMENT LP	0.6%	500K	3.85M	500K	+100.00%
Dec 31, 2025	EMPIRICAL FINANCIAL SERVICES, LLC D.B.A. EMPIRICAL WEALTH MANAGEMENT	0.2%	167.4K	1.29M	-1.8K	-1.06%
Dec 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.21%	171.17K	1.32M	-6.62K	-3.72%
Dec 31, 2025	BIOIMPACT CAPITAL LLC	3.31%	2.74M	21.13M	2.74M	+100.00%
Dec 31, 2025	SHELTON WEALTH MANAGEMENT, LLC	0.02%	15.64K	120.41K	1.9K	+13.80%
Dec 31, 2025	SOWELL FINANCIAL SERVICES LLC	0.02%	17K	130.9K	5K	+41.67%
Dec 31, 2025	GROUP ONE TRADING, L.P.	0.03%	26.67K	205.34K	26.67K	+100.00%
Dec 31, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.03%	27.66K	212.99K	27.66K	+100.00%
Dec 31, 2025	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.03%	28.12K	216.5K	28.12K	+100.00%
Dec 31, 2025	QUEST PARTNERS LLC	0.04%	35.97K	276.98K	35.97K	+100.00%
Dec 31, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.04%	35.97K	276.99K	9.81K	+37.51%
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.78%	1.47M	11.35M	16.5K	+1.13%
Dec 31, 2025	VIVO CAPITAL, LLC	2.7%	2.23M	17.21M	0	0
Sep 30, 2025	PKS ADVISORY SERVICES, LLC	0.01%	10.5K	77.39K	0	0
Sep 30, 2025	TWO SIGMA INVESTMENTS, LP	0.26%	203.36K	1.5M	-20.55K	-9.18%
Sep 30, 2025	VIVO CAPITAL, LLC	2.87%	2.23M	16.47M	0	0
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.87%	1.46M	10.74M	94.79K	+6.96%
Sep 30, 2025	ORBIMED ADVISORS LLC	9.21%	7.17M	52.81M	0	0
Sep 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	8.3%	6.45M	47.57M	-588.1K	-8.35%
Sep 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.03%	26.16K	192.81K	383	+1.49%
Sep 30, 2025	PALUMBO WEALTH MANAGEMENT LLC	0.03%	23.61K	174.04K	23.61K	+100.00%
Sep 30, 2025	THREE BRIDGE WEALTH ADVISORS, LLC	0.03%	22.37K	164.87K	0	0
Sep 30, 2025	COMMERCE BANK	0.03%	20K	147.4K	0	0
Sep 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.02%	18.8K	138.56K	-5K	-21.01%
Sep 30, 2025	MASSO TORRENCE WEALTH MANAGEMENT INC.	0.02%	17K	125.29K	-33K	-66.00%
Sep 30, 2025	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0.02%	15.53K	114.46K	3.27K	+26.69%
Sep 30, 2025	SHELTON WEALTH MANAGEMENT, LLC	0.02%	13.74K	101.28K	13.74K	+100.00%
Sep 30, 2025	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.02%	13.06K	96.26K	-2.43K	-15.67%
Sep 30, 2025	PROSHARE ADVISORS LLC	0.02%	12.79K	94.23K	-835	-6.13%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.02%	12.52K	92.24K	6.98K	+125.88%
Sep 30, 2025	SOWELL FINANCIAL SERVICES LLC	0.02%	12K	88.44K	0	0
Sep 30, 2025	WHITTIER TRUST CO OF NEVADA INC	0.01%	11.2K	80.53K	0	0
Sep 30, 2025	RESOURCES INVESTMENT ADVISORS, LLC.	0.01%	10K	73.7K	0	0
Sep 30, 2025	ROTHSCHILD INVESTMENT LLC	0.01%	7K	51.59K	0	0
Sep 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0.01%	6.66K	49.09K	6.66K	+100.00%
Sep 30, 2025	LEGAL & GENERAL GROUP PLC	0.01%	6.52K	48.08K	691	+11.85%
Sep 30, 2025	AMERITAS INVESTMENT PARTNERS, INC.	0.01%	5.35K	39.42K	0	0
Sep 30, 2025	CITIGROUP INC	0.01%	3.95K	29.1K	-19.72K	-83.32%
Sep 30, 2025	NORTHWEST CAPITAL MANAGEMENT INC	0%	3.4K	25.04K	0	0
Sep 30, 2025	MIRAE ASSET GLOBAL INVESTMENTS CO., LTD.	0%	2.88K	21.23K	-98	-3.29%
Sep 30, 2025	WESTERN PACIFIC WEALTH MANAGEMENT, LP	0%	2K	14.74K	0	0
Sep 30, 2025	AMALGAMATED BANK	0%	1.79K	13K	0	0
Sep 30, 2025	GF FUND MANAGEMENT CO. LTD.	0%	1.6K	11.81K	9	+0.56%
Sep 30, 2025	FMR LLC	0%	1.47K	10.85K	1.24K	+529.06%
Sep 30, 2025	TWO SIGMA ADVISERS, LP	0.21%	161.6K	1.19M	-51.1K	-24.02%
Sep 30, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.04%	33.59K	247.59K	1.5K	+4.68%
Sep 30, 2025	BARCLAYS PLC	0.4%	309.15K	2.28M	-34.37K	-10.01%
Sep 30, 2025	DEUTSCHE BANK AG\	0.07%	53.64K	395.32K	9.65K	+21.94%
Sep 30, 2025	PERCEPTIVE ADVISORS LLC	1.85%	1.44M	10.6M	0	0
Sep 30, 2025	STATE STREET CORP	1.29%	1.01M	7.42M	341.55K	+51.38%
Sep 30, 2025	UBS GROUP AG	0.21%	162.07K	1.19M	72.36K	+80.66%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.23%	177.79K	1.31M	15.97K	+9.87%
Sep 30, 2025	ROYAL BANK OF CANADA	0.08%	60.84K	448K	-54.11K	-47.07%
Sep 30, 2025	ANCORA ADVISORS, LLC	0.06%	47.29K	348.53K	4.18K	+9.70%
Sep 30, 2025	CITADEL ADVISORS LLC	0.06%	42.77K	315.19K	42.77K	+100.00%
Sep 30, 2025	MORGAN STANLEY	0.79%	617.22K	4.55M	-277.18K	-30.99%
Sep 30, 2025	NORTHERN TRUST CORP	0.6%	466.49K	3.44M	63.34K	+15.71%
Sep 30, 2025	GSA CAPITAL PARTNERS LLP	0.52%	401.41K	2.96M	82.68K	+25.94%
Sep 30, 2025	TOWERVIEW LLC	0.22%	170K	1.25M	0	0
Sep 30, 2025	HIKARI POWER LTD	0.06%	49.96K	368K	0	0
Sep 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.06%	44.1K	325.02K	16.7K	+60.95%
Sep 30, 2025	INVESCO LTD.	0.05%	38.67K	285.02K	-1.93K	-4.76%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0.05%	36.4K	268.23K	9.33K	+34.45%
Sep 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.23%	180.18K	1.33M	77.83K	+76.04%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.2%	151.97K	1.12M	19.24K	+14.49%
Sep 30, 2025	EMPIRICAL FINANCIAL SERVICES, LLC D.B.A. EMPIRICAL WEALTH MANAGEMENT	0.22%	169.2K	1.25M	1.2K	+0.71%
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.16%	126.53K	932.51K	15.84K	+14.31%
Sep 30, 2025	JACKSON SQUARE CAPITAL, LLC	0.08%	63.77K	470.01K	0	0
Sep 30, 2025	NEOS INVESTMENT MANAGEMENT LLC	0.08%	59.2K	436.32K	59.2K	+100.00%
Sep 30, 2025	TEMA ETFS LLC	0.08%	59.2K	436.32K	59.2K	+100.00%
Sep 30, 2025	DIADEMA PARTNERS LP	0.06%	50K	368.5K	50K	+100.00%
Sep 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	0.04%	32.41K	239K	6.11K	+23.23%
Sep 30, 2025	JPMORGAN CHASE & CO	0.04%	32.23K	237.55K	1.81K	+5.96%
Sep 30, 2025	ARGENT ADVISORS, INC.	0.04%	30K	221.1K	0	0
Sep 30, 2025	JAIN GLOBAL LLC	0.04%	27.62K	203.55K	27.62K	+100.00%
Sep 30, 2025	MIRAE ASSET GLOBAL ETFS HOLDINGS LTD.	0.04%	27.53K	202.86K	-1.14K	-3.96%
Sep 30, 2025	AXQ CAPITAL, LP	0.03%	27.05K	199.37K	27.05K	+100.00%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	0.57%	445.67K	3.28M	275.46K	+161.83%
Sep 30, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.52%	407.71K	3M	224.62K	+122.68%
Sep 30, 2025	BLACKROCK, INC.	6.06%	4.71M	34.72M	472.03K	+11.14%
Sep 30, 2025	VANGUARD GROUP INC	4.46%	3.47M	25.59M	191.22K	+5.83%
Sep 30, 2025	ADAMS STREET PARTNERS LLC	4.21%	3.28M	24.14M	0	0
Sep 30, 2025	RTW INVESTMENTS, LP	3.45%	2.68M	19.75M	0	0
Sep 30, 2025	FORESITE CAPITAL MANAGEMENT VI LLC	2.23%	1.73M	12.76M	0	0
Sep 30, 2025	RAYMOND JAMES FINANCIAL INC	0.16%	124.5K	917.54K	0	0
Sep 30, 2025	STEMPOINT CAPITAL LP	0.12%	96.44K	710.76K	96.44K	+100.00%
Sep 30, 2025	RHUMBLINE ADVISERS	0.11%	82.59K	608.68K	6.64K	+8.74%
Sep 30, 2025	HSBC HOLDINGS PLC	0.11%	82.39K	586.6K	-1.89K	-2.24%
Sep 30, 2025	JANE STREET GROUP, LLC	0.09%	68.07K	501.65K	57.95K	+572.72%
Sep 30, 2025	NUVEEN, LLC	0.09%	68.06K	501.63K	0	0
Sep 30, 2025	ADVISOR GROUP HOLDINGS, INC.	0.09%	67.99K	390.28K	670	+1.00%
Sep 30, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.09%	66.7K	491.58K	0	0
Jun 30, 2025	BARCLAYS PLC	0.44%	343.53K	1.37M	260.3K	+312.74%
Jun 30, 2025	FORESITE CAPITAL MANAGEMENT VI LLC	2.23%	1.73M	6.92M	150K	+9.49%
Jun 30, 2025	VIVO CAPITAL, LLC	2.87%	2.23M	8.94M	0	0
Jun 30, 2025	ANCORA ADVISORS, LLC	0.06%	43.11K	172.43K	5.24K	+13.83%
Jun 30, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.06%	43.97K	175.88K	-405.11K	-90.21%
Jun 30, 2025	RHUMBLINE ADVISERS	0.1%	75.95K	303.8K	75.16K	+9,501.77%
Jun 30, 2025	EMPIRICAL FINANCIAL SERVICES, LLC D.B.A. EMPIRICAL WEALTH MANAGEMENT	0.22%	168K	672K	168K	+100.00%
Jun 30, 2025	TOWERVIEW LLC	0.22%	170K	680K	42.5K	+33.33%
Jun 30, 2025	INVESCO LTD.	0.05%	40.61K	162.43K	40.61K	+100.00%
Jun 30, 2025	CITADEL ADVISORS LLC	0.05%	38.2K	152.8K	-66.5K	-63.51%
Jun 30, 2025	VANGUARD GROUP INC	4.22%	3.28M	13.12M	786.56K	+31.54%
Jun 30, 2025	BLACKROCK, INC.	5.45%	4.24M	16.95M	3.18M	+300.98%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.22%	170.21K	680.84K	-198.11K	-53.79%
Jun 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	9.05%	7.04M	28.17M	4.25M	+152.63%
Jun 30, 2025	ORBIMED ADVISORS LLC	9.21%	7.17M	28.66M	221.35K	+3.19%
Jun 30, 2025	NORTHERN TRUST CORP	0.52%	403.15K	1.61M	293.85K	+268.86%
Jun 30, 2025	MILLENNIUM MANAGEMENT LLC	0.19%	150K	600K	100K	+200.00%
Jun 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.21%	165.19K	660.75K	-99.8K	-37.66%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.21%	161.82K	647.28K	131.85K	+439.98%
Jun 30, 2025		0.09%	68.06K	272.26K	68.06K	+100.00%
Jun 30, 2025	ADVISOR GROUP HOLDINGS, INC.	0.09%	67.32K	269.29K	-667	-0.98%
Jun 30, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.09%	66.7K	266.8K	25.4K	+61.50%
Jun 30, 2025	DEUTSCHE BANK AG\	0.06%	43.99K	175.95K	43.99K	+100.00%
Jun 30, 2025	HIKARI POWER LTD	0.06%	49.96K	200K	0	0
Jun 30, 2025	MASSO TORRENCE WEALTH MANAGEMENT INC.	0.06%	50K	200K	15K	+42.86%
Jun 30, 2025	JACKSON SQUARE CAPITAL, LLC	0.08%	63.77K	255.09K	0	0
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.05%	42.6K	170.4K	-83.3K	-66.16%
Jun 30, 2025	HSBC HOLDINGS PLC	0.11%	84.27K	332.04K	84.27K	+100.00%
Jun 30, 2025	UBS GROUP AG	0.12%	89.71K	358.86K	53.32K	+146.51%
Jun 30, 2025	BML CAPITAL MANAGEMENT, LLC	0.15%	118.77K	475.06K	118.77K	+100.00%
Jun 30, 2025	RAYMOND JAMES FINANCIAL INC	0.16%	124.5K	497.98K	16.38K	+15.15%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0.17%	132.73K	530.92K	34.18K	+34.68%
Jun 30, 2025	NUVEEN, LLC	0.09%	68.06K	272.26K	68.06K	+100.00%
Jun 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.13%	102.35K	409.39K	-2.53K	-2.41%
Jun 30, 2025	BANK OF NEW YORK MELLON CORP	0.14%	110.69K	442.75K	110.69K	+100.00%
Jun 30, 2025	DCF ADVISERS, LLC	0.97%	757.5K	3.03M	357.5K	+89.38%
Jun 30, 2025	STATE STREET CORP	0.85%	664.77K	2.66M	434.73K	+188.98%
Jun 30, 2025	MARSHALL WACE, LLP	0.26%	201.65K	806.6K	46.88K	+30.29%
Jun 30, 2025	RTW INVESTMENTS, LP	3.45%	2.68M	10.72M	0	0
Jun 30, 2025	TWO SIGMA ADVISERS, LP	0.27%	212.7K	850.8K	-23.7K	-10.03%
Jun 30, 2025	TWO SIGMA INVESTMENTS, LP	0.29%	223.91K	895.65K	-84.44K	-27.38%
Jun 30, 2025	GSA CAPITAL PARTNERS LLP	0.41%	318.73K	1.28M	318.73K	+100.00%
Jun 30, 2025	ADAMS STREET PARTNERS LLC	4.21%	3.28M	13.1M	0	0
Jun 30, 2025	PERCEPTIVE ADVISORS LLC	1.85%	1.44M	5.75M	1.44M	+100.00%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.75%	1.36M	5.45M	771.45K	+130.69%
Jun 30, 2025	MORGAN STANLEY	1.15%	894.41K	3.58M	220.88K	+32.79%
Jun 30, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.24%	183.09K	732.38K	-22.77K	-11.06%
Jun 30, 2025	ROYAL BANK OF CANADA	0.15%	114.95K	460K	114.95K	+100.00%
Jun 30, 2025	SQUAREPOINT OPS LLC	0.18%	138.46K	553.85K	37.43K	+37.05%
Mar 31, 2025	SAMLYN CAPITAL, LLC	5.64%	4.07M	12.93M	-2.6M	-39.02%
Mar 31, 2025	SPHERA FUNDS MANAGEMENT LTD.	0.29%	205.86K	654.63K	-294.63K	-58.87%
Mar 31, 2025	ORBIMED ADVISORS LLC	9.63%	6.94M	22.08M	0	0
Mar 31, 2025	JACKSON SQUARE CAPITAL, LLC	0.09%	63.77K	202.8K	0	0
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.51%	368.32K	1.17M	-216.23K	-36.99%
Mar 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.13%	93.2K	296.38K	-31.1K	-25.02%
Mar 31, 2025	IKARIAN CAPITAL, LLC	0.47%	338.1K	1.08M	-416.3K	-55.18%
Mar 31, 2025	GRAHAM CAPITAL MANAGEMENT, L.P.	0.09%	67.55K	214.81K	49.25K	+269.02%
Mar 31, 2025	MORGAN STANLEY	0.93%	673.52K	2.14M	276.16K	+69.50%
Mar 31, 2025	BLACKROCK, INC.	1.47%	1.06M	3.36M	-15.92K	-1.48%
Mar 31, 2025	FORESITE CAPITAL MANAGEMENT VI LLC	2.19%	1.58M	5.03M	0	0
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.82%	590.29K	1.88M	23.42K	+4.13%
Mar 31, 2025	TWO SIGMA INVESTMENTS, LP	0.43%	308.35K	980.55K	278.05K	+917.52%
Mar 31, 2025	RTW INVESTMENTS, LP	3.71%	2.68M	8.52M	0	0
Mar 31, 2025	CAPTION MANAGEMENT, LLC	0.07%	50K	159K	-581.2K	-92.08%
Mar 31, 2025	VIVO CAPITAL, LLC	3.1%	2.23M	7.11M	0	0
Mar 31, 2025	VANGUARD GROUP INC	3.46%	2.49M	7.93M	39.55K	+1.61%
Mar 31, 2025	POINT72 ASSET MANAGEMENT, L.P.	3.86%	2.79M	8.86M	-242.38K	-8.00%
Mar 31, 2025	TOWERVIEW LLC	0.18%	127.5K	405.45K	50K	+64.52%
Mar 31, 2025	MARSHALL WACE, LLP	0.21%	154.77K	492.17K	154.77K	+100.00%
Mar 31, 2025	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.28%	199.36K	634K	185.84K	+1,374.98%
Mar 31, 2025	ADVISOR GROUP HOLDINGS, INC.	0.09%	67.99K	216.2K	0	0
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	0.07%	50K	159K	50K	+100.00%
Mar 31, 2025	ENTRYPOINT CAPITAL, LLC	0.07%	53.75K	170.91K	-62.9K	-53.92%
Mar 31, 2025	BALYASNY ASSET MANAGEMENT L.P.	0.08%	57.83K	183.89K	9.49K	+19.64%
Mar 31, 2025	CITADEL ADVISORS LLC	0.09%	61.68K	196.13K	-17.04K	-21.64%
Mar 31, 2025	AMERICAN CENTURY COMPANIES INC	0.12%	89.27K	283.86K	45.49K	+103.92%
Mar 31, 2025	HRT FINANCIAL LP	0.11%	81.93K	260K	65.54K	+399.92%
Mar 31, 2025	OMERS ADMINISTRATION CORP	0.11%	82.3K	261.71K	6.8K	+9.01%
Mar 31, 2025	BARCLAYS PLC	0.12%	83.23K	264K	-22.79K	-21.49%
Mar 31, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.14%	98K	311.64K	-120.6K	-55.17%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0.14%	98.55K	313.39K	1.57K	+1.62%
Mar 31, 2025	SQUAREPOINT OPS LLC	0.14%	101.03K	321.28K	2.89K	+2.94%
Mar 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.15%	104.87K	333.49K	104.87K	+100.00%
Mar 31, 2025	RAYMOND JAMES FINANCIAL INC	0.15%	108.12K	343.81K	-872	-0.80%
Mar 31, 2025	NORTHERN TRUST CORP	0.15%	109.3K	347.56K	3.28K	+3.10%
Mar 31, 2025	STATE STREET CORP	0.32%	230.04K	731.52K	24.5K	+11.92%
Mar 31, 2025	TWO SIGMA ADVISERS, LP	0.33%	236.4K	751.75K	218.5K	+1,220.67%
Mar 31, 2025	JANE STREET GROUP, LLC	0.36%	257.8K	819.81K	142.85K	+124.27%
Mar 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0.37%	264.99K	842.66K	-125.7K	-32.17%
Mar 31, 2025	DCF ADVISERS, LLC	0.55%	400K	1.27M	400K	+100.00%
Mar 31, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.62%	449.08K	1.43M	-970	-0.22%
Mar 31, 2025	ADAMS STREET PARTNERS LLC	4.54%	3.28M	10.42M	0	0
Mar 31, 2024	AVITY INVESTMENT MANAGEMENT INC.	0.02%	11.48K	20.43K	0	0
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.03%	15K	26.7K	1.6K	+11.94%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.03%	15.67K	27.89K	0	0
Mar 31, 2024	RESOURCES INVESTMENT ADVISORS, LLC.	0.04%	17.95K	31.95K	5.55K	+44.76%
Mar 31, 2024	AMERICAN CENTURY COMPANIES INC	0.04%	18.25K	32.48K	-214	-1.16%
Mar 31, 2024	COMMERCE BANK	0.04%	20K	35.6K	0	0
Mar 31, 2024	QUINN OPPORTUNITY PARTNERS LLC	0.05%	22.33K	39.74K	22.33K	+100.00%
Mar 31, 2024	MILLENNIUM MANAGEMENT LLC	0.05%	23.28K	41.44K	-17.55K	-42.99%
Mar 31, 2024	HIKARI POWER LTD	0.1%	49.96K	89K	0	0
Mar 31, 2024	JPMORGAN CHASE & CO	0.11%	52.82K	94.03K	52.15K	+7,679.68%
Mar 31, 2024	JACKSON SQUARE CAPITAL, LLC	0.13%	63.77K	113.52K	0	0
Mar 31, 2024	NORTHERN TRUST CORP	0.13%	64.95K	115.61K	-68	-0.10%
Mar 31, 2024	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.18%	88.01K	156.65K	16.8K	+23.59%
Mar 31, 2024	TWO SIGMA INVESTMENTS, LP	0.21%	102.45K	182.36K	-78.26K	-43.31%
Mar 31, 2024	STATE STREET CORP	0.25%	120.3K	214.14K	-18.1K	-13.08%
Mar 31, 2024	TWO SIGMA ADVISERS, LP	0.38%	185.1K	329.48K	-50.5K	-21.43%
Mar 31, 2024	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.46%	224.3K	399.25K	75K	+50.23%
Mar 31, 2024	MORGAN STANLEY	0.56%	275.36K	490.14K	15.71K	+6.05%
Mar 31, 2024	BVF INC/IL	0.74%	361.41K	643.3K	-1.01M	-73.64%
Mar 31, 2024	SAMLYN CAPITAL, LLC	4.79%	2.35M	4.18M	-147.9K	-5.92%
Mar 31, 2024	ORBIMED ADVISORS LLC	14.16%	6.94M	12.36M	0	0
Mar 31, 2024	NATIXIS	0%	0	-	-800	-100.00%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0%	0	-	-22	-100.00%
Mar 31, 2024	ICA GROUP WEALTH MANAGEMENT, LLC	0%	165	294	165	+100.00%
Mar 31, 2024	WELLS FARGO & COMPANY/MN	0%	265	472	5	+1.92%
Mar 31, 2024	RHUMBLINE ADVISERS	0%	791	1.41K	0	0
Mar 31, 2024	ADVISOR GROUP HOLDINGS, INC.	0%	1.2K	2.14K	0	0
Mar 31, 2024	QUBE RESEARCH & TECHNOLOGIES LTD	0%	2.38K	4.23K	2.38K	+100.00%
Mar 31, 2024	NORTHWEST CAPITAL MANAGEMENT INC	0.01%	3.4K	6.05K	0	0
Mar 31, 2024	GROUP ONE TRADING, L.P.	0.01%	4.6K	8.2K	-32.06K	-87.44%
Mar 31, 2024	UBS GROUP AG	0.01%	4.68K	8.33K	-2.02K	-30.16%
Mar 31, 2024	CITADEL ADVISORS LLC	0.01%	6.7K	11.93K	-29.5K	-81.49%
Mar 31, 2024	BLACKROCK INC.	1.07%	522.98K	930.9K	2.43K	+0.47%
Mar 31, 2024	RENAISSANCE TECHNOLOGIES LLC	1.3%	637.03K	1.13M	49.6K	+8.44%
Mar 31, 2024	ADAMS STREET PARTNERS LLC	6.68%	3.28M	5.83M	0	0
Mar 31, 2024	FMR LLC	0%	17	30	17	+100.00%
Mar 31, 2024	PARALLEL ADVISORS, LLC	0%	20	36	0	0
Mar 31, 2024	SIMPLEX TRADING, LLC	0.02%	9.35K	16K	-40.29K	-81.17%
Mar 31, 2024	MASSO TORRENCE WEALTH MANAGEMENT INC.	0.02%	10K	17.8K	0	0
Mar 31, 2024	FORTEM FINANCIAL GROUP, LLC	0.02%	11K	19.58K	11K	+100.00%
Mar 31, 2024	WHITTIER TRUST CO OF NEVADA INC	0.02%	11.2K	19.82K	0	0
Mar 31, 2024	TOWER RESEARCH CAPITAL LLC (TRC)	0.02%	11.51K	20.49K	3.01K	+35.38%
Mar 31, 2024	DIMENSIONAL FUND ADVISORS LP	0.02%	11.92K	21.23K	0	0
Mar 31, 2024	VIRTU FINANCIAL LLC	0.03%	12.57K	22K	12.57K	+100.00%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	0.76%	371.76K	661.89K	11.38K	+3.16%
Mar 31, 2024	TOWERVIEW LLC	0.78%	382.5K	680.85K	-54.37K	-12.45%
Mar 31, 2024	VANGUARD GROUP INC	3.05%	1.49M	2.66M	142.72K	+10.57%
Mar 31, 2024	XTX TOPCO LTD	0%	0	-	-23.42K	-100.00%
Mar 31, 2024	MYDA ADVISORS LLC	0%	0	-	-71.01K	-100.00%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0%	0	-	-21.22K	-100.00%
Dec 31, 2023	RHUMBLINE ADVISERS	0%	791	1.39K	0	0
Dec 31, 2023	JPMORGAN CHASE & CO	0%	679	1.2K	-69.23K	-99.03%
Dec 31, 2023	WELLS FARGO & COMPANY/MN	0%	260	458	13	+5.26%
Dec 31, 2023	IFP ADVISORS, INC	0%	24	42	0	0
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0%	22	39	-3.15K	-99.31%
Dec 31, 2023	PARALLEL ADVISORS, LLC	0%	20	35	0	0
Dec 31, 2023	BARCLAYS PLC	0%	0	-	-13.68K	-100.00%
Dec 31, 2023	FMR LLC	0%	0	-	-1.1K	-100.00%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0%	0	-	-49.32K	-100.00%
Dec 31, 2023	ORBIMED ADVISORS LLC	14.18%	6.94M	12.22M	0	0
Dec 31, 2023	ADAMS STREET PARTNERS LLC	6.69%	3.28M	5.77M	0	0
Dec 31, 2023	SAMLYN CAPITAL, LLC	5.1%	2.5M	4.39M	90.5K	+3.76%
Dec 31, 2023	JACKSON SQUARE CAPITAL, LLC	0.13%	63.77K	112.24K	0	0
Dec 31, 2023	NORTHERN TRUST CORP	0.13%	65.02K	114.43K	0	0
Dec 31, 2023	MYDA ADVISORS LLC	0.15%	71.01K	124.98K	2.2K	+3.19%
Dec 31, 2023	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.15%	71.21K	125.33K	325	+0.46%
Dec 31, 2023	VANGUARD GROUP INC	2.76%	1.35M	2.38M	3.7K	+0.27%
Dec 31, 2023	BVF INC/IL	2.8%	1.37M	2.41M	0	0
Dec 31, 2023	RENAISSANCE TECHNOLOGIES LLC	1.2%	587.43K	1.03M	165.69K	+39.29%
Dec 31, 2023	BLACKROCK INC.	1.06%	520.55K	916.17K	-700	-0.13%
Dec 31, 2023	TOWERVIEW LLC	0.89%	436.87K	768.9K	94.4K	+27.56%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	0.74%	360.38K	634.41K	0	0
Dec 31, 2023	MORGAN STANLEY	0.53%	259.66K	456.99K	67.15K	+34.88%
Dec 31, 2023	STATE STREET CORP	0.28%	138.4K	243.59K	0	0
Dec 31, 2023	TWO SIGMA ADVISERS, LP	0.48%	235.6K	414.66K	-13.3K	-5.34%
Dec 31, 2023	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.3%	149.3K	262.77K	0	0
Dec 31, 2023	SIMPLEX TRADING, LLC	0.1%	49.63K	87K	10.14K	+25.67%
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	0.08%	40.84K	71.87K	-67.19K	-62.20%
Dec 31, 2023	GROUP ONE TRADING, L.P.	0.07%	36.66K	64.53M	9.57K	+35.30%
Dec 31, 2023	CITADEL ADVISORS LLC	0.02%	7.65K	13.47K	7.47K	+4,082.51%
Dec 31, 2023	XTX TOPCO LTD	0.05%	23.42K	41.21K	4.17K	+21.67%
Dec 31, 2023	JANE STREET GROUP, LLC	0.05%	23.1K	40.65K	23.1K	+100.00%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.04%	21.22K	37.35K	0	0
Dec 31, 2023	COMMERCE BANK	0.04%	20K	35.2K	0	0
Dec 31, 2023	AMERICAN CENTURY COMPANIES INC	0.04%	18.46K	32.49K	-292	-1.56%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.03%	15.67K	27.58K	0	0
Dec 31, 2023	TWO SIGMA INVESTMENTS, LP	0.37%	180.7K	318.04K	-92.3K	-33.81%
Dec 31, 2023	HIKARI POWER LTD	0.1%	49.96K	88K	0	0
Dec 31, 2023	RESOURCES INVESTMENT ADVISORS, LLC.	0.03%	12.4K	21.82K	12.4K	+100.00%
Dec 31, 2023	DIMENSIONAL FUND ADVISORS LP	0.02%	11.92K	20.99K	-2.97K	-19.92%
Dec 31, 2023	AVITY INVESTMENT MANAGEMENT INC.	0.02%	11.48K	20.21K	0	0
Dec 31, 2023	WHITTIER TRUST CO OF NEVADA INC	0.02%	11.2K	19.6K	0	0
Dec 31, 2023	MASSO TORRENCE WEALTH MANAGEMENT INC.	0.02%	10K	17.6K	0	0
Dec 31, 2023	TOWER RESEARCH CAPITAL LLC (TRC)	0.02%	8.5K	14.97K	-16.23K	-65.63%
Dec 31, 2023	UBS GROUP AG	0.01%	6.7K	11.79K	0	0
Dec 31, 2023	NORTHWEST CAPITAL MANAGEMENT INC	0.01%	3.4K	5.98K	0	0
Dec 31, 2023	ADVISOR GROUP HOLDINGS, INC.	0%	1.2K	2.11K	-1.2K	-50.00%
Dec 31, 2023	NATIXIS	0%	800	1.41K	0	0

Insiders

Among the CRVS insiders holding of 3.96% of the stake in company, ORBIMED ADVISORS LLC, , holds the largest shares of 7.17M. THOMPSON PETER A., , is the second largest CRVS insider with ownership of 7.17M shares. NOVO A/S, 10 percent owner, stands third with possession of 3.22M shares of that stake.

Insiders	Designation	Shares Held
ORBIMED ADVISORS LLC		7.17M
THOMPSON PETER A.		7.17M
NOVO A/S	10 percent owner	3.22M
NOVO HOLDINGS A/S	10 percent owner	1.39M
MILLER RICHARD A MD	President and CEO	559.07K
LEA LEIV	Chief Financial Officer	133.24K
ECOR1 CAPITAL, LLC	10 percent owner	81.08K
GOULD TERRY P		67.77K
ADAMS STREET PARTNERS LLC	10 percent owner	67.77K
JONES WILLIAM BENTON	See Remarks	19.36K
GRAIS LINDA	director	10K

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Jun 27, 2025	ORBIMED ADVISORS LLC	SALE	4.16	1.18M	4.89M	7.17M
Jun 27, 2025	THOMPSON PETER A.	SALE	4.16	1.18M	4.89M	7.17M
May 06, 2024	MILLER RICHARD A MD	PURCHASE	3.50	559.07K	1.96M	559.07K
May 06, 2024	JONES WILLIAM BENTON	PURCHASE	3.50	19.36K	67.75K	19.36K
May 06, 2024	THOMPSON PETER A.	PURCHASE	3.50	1.4M	4.89M	1.4M
May 06, 2024	ORBIMED ADVISORS LLC	PURCHASE	3.50	1.4M	4.89M	1.4M
May 15, 2023	GRAIS LINDA	PURCHASE	2.45	10K	24.5K	10K
Dec 20, 2022	JONES WILLIAM BENTON	PURCHASE	0.79	20K	15.8K	133.77K
Dec 14, 2022	MILLER RICHARD A MD	PURCHASE	0.78	10K	7.81K	1.49M
Dec 14, 2022	LEA LEIV	PURCHASE	0.84	4K	3.36K	133.24K
Dec 13, 2022	MILLER RICHARD A MD	PURCHASE	0.74	50K	37.02K	1.48M
Dec 13, 2022	LEA LEIV	PURCHASE	0.74	30K	22.28K	129.24K
Sep 28, 2022	MILLER RICHARD A MD	PURCHASE	0.76	25K	19.07K	1.39M
Sep 20, 2022	MILLER RICHARD A MD	PURCHASE	0.81	12.3K	9.96K	1.36M
Jun 24, 2022	MILLER RICHARD A MD	PURCHASE	1.03	5K	5.15K	1.34M
Jun 02, 2022	MILLER RICHARD A MD	PURCHASE	0.98	4.83K	4.73K	1.34M
Mar 31, 2022	MILLER RICHARD A MD	PURCHASE	1.64	15K	24.53K	1.33M
Mar 16, 2022	LEA LEIV	PURCHASE	1.65	13.88K	22.9K	99.24K
Mar 15, 2022	MILLER RICHARD A MD	PURCHASE	1.47	25K	36.65K	1.31M
Oct 01, 2021	ECOR1 CAPITAL, LLC	SALE	4.96	2M	9.93M	81.08K
Sep 30, 2021	ECOR1 CAPITAL, LLC	SALE	5.04	3M	15.13M	2.08M
Sep 20, 2021	THOMPSON PETER A.	SALE	6.09	1.11M	6.76M	6.94M
Sep 20, 2021	ORBIMED ADVISORS LLC	SALE	6.09	1.11M	6.76M	6.94M
Aug 20, 2021	MILLER RICHARD A MD	PURCHASE	1.93	10K	19.25K	1.29M
May 04, 2021	MILLER RICHARD A MD	PURCHASE	2.80	35.71K	100K	35.71K
Feb 17, 2021	THOMPSON PETER A.	PURCHASE	3.50	1.29M	4.5M	8.05M
Feb 17, 2021	ORBIMED ADVISORS LLC	PURCHASE	3.50	1.29M	4.5M	8.05M
Feb 17, 2021	MILLER RICHARD A MD	PURCHASE	3.50	100K	350K	1.28M
Jul 08, 2020	NOVO HOLDINGS A/S	SALE	5.37	741.44K	3.99M	1.39M
Jul 07, 2020	NOVO HOLDINGS A/S	SALE	5.25	796.62K	4.18M	2.13M
Nov 13, 2019	MILLER RICHARD A MD	PURCHASE	3.00	14.74K	44.24K	1.18M
Nov 12, 2019	MILLER RICHARD A MD	PURCHASE	2.90	272	788.8	1.16M
Aug 07, 2019	MILLER RICHARD A MD	PURCHASE	3.54	2.5K	8.85K	1.16M
Aug 06, 2019	THOMPSON PETER A.	PURCHASE	3.51	142.66K	500.72K	6.77M
Aug 06, 2019	MILLER RICHARD A MD	PURCHASE	3.58	5K	17.88K	1.16M
Aug 06, 2019	ORBIMED ADVISORS LLC	PURCHASE	3.51	142.66K	500.72K	6.77M
Jul 25, 2019	NOVO HOLDINGS A/S	SALE	4.00	1.4M	5.6M	2.93M
Jul 24, 2019	NOVO HOLDINGS A/S	SALE	5.01	53.24K	266.71K	4.33M
Jul 23, 2019	NOVO HOLDINGS A/S	SALE	5.32	39.72K	211.13K	4.38M
Jul 01, 2019	ORBIMED ADVISORS LLC	PURCHASE	3.91	59.24K	231.64K	6.62M
Jul 01, 2019	THOMPSON PETER A.	PURCHASE	3.91	59.24K	231.64K	6.62M
Jun 28, 2019	ORBIMED ADVISORS LLC	PURCHASE	3.72	565.18K	2.1M	6.57M
Jun 28, 2019	THOMPSON PETER A.	PURCHASE	3.72	565.18K	2.1M	6.57M
Jun 27, 2019	ORBIMED ADVISORS LLC	PURCHASE	3.34	32.92K	109.96K	6M
Jun 27, 2019	THOMPSON PETER A.	PURCHASE	3.34	32.92K	109.96K	6M
Jun 14, 2019	MILLER RICHARD A MD	PURCHASE	3.40	11.66K	39.67K	1.16M
Jun 13, 2019	MILLER RICHARD A MD	PURCHASE	3.52	343	1.21K	1.14M
Jun 11, 2019	MILLER RICHARD A MD	PURCHASE	3.67	6K	22.02K	1.14M
Jun 07, 2019	LEA LEIV	PURCHASE	3.38	10K	33.8K	50.2K
Jun 07, 2019	MILLER RICHARD A MD	PURCHASE	3.37	9.21K	31.02K	1.14M
Jun 06, 2019	LEA LEIV	PURCHASE	3.56	15.5K	55.18K	40.2K
Dec 27, 2018	MILLER RICHARD A MD	PURCHASE	3.29	20K	65.88K	1.13M
Dec 21, 2018	LEA LEIV	PURCHASE	4.15	24.7K	102.41K	24.7K
Dec 20, 2018	MILLER RICHARD A MD	PURCHASE	4.40	5K	22K	1.1M
Dec 06, 2018	MILLER RICHARD A MD	PURCHASE	5.99	5K	29.93K	1.12M
Dec 04, 2018	MILLER RICHARD A MD	PURCHASE	5.95	1.5K	8.94K	1.11M
Mar 12, 2018	MILLER RICHARD A MD	PURCHASE	8.50	100K	850K	1.11M
Mar 12, 2018	THOMPSON PETER A.	PURCHASE	8.50	588.24K	5M	5.97M
Mar 12, 2018	NOVO HOLDINGS A/S	PURCHASE	8.50	1.18M	10M	4.42M
Mar 12, 2018	GOULD TERRY P	PURCHASE	8.50	67.77K	576.04K	67.77K
Mar 12, 2018	ADAMS STREET PARTNERS LLC	PURCHASE	8.50	67.77K	576.04K	67.77K
Mar 12, 2018	ORBIMED ADVISORS LLC	PURCHASE	8.50	588.24K	5M	5.97M
Nov 20, 2017	MILLER RICHARD A MD	PURCHASE	10.79	10K	107.85K	1.01M
Jun 23, 2017	NOVO HOLDINGS A/S	PURCHASE	10.95	20K	219K	3.24M
Jun 13, 2017	MILLER RICHARD A MD	PURCHASE	9.75	2.5K	24.38K	999.79K
Jun 12, 2017	MILLER RICHARD A MD	PURCHASE	9.82	11.22K	110.18K	997.29K
Jun 09, 2017	MILLER RICHARD A MD	PURCHASE	9.95	5K	49.75K	982.29K
Jun 24, 2016	ORBIMED ADVISORS LLC	PURCHASE	12.99	900	11.69K	5.38M
Jun 24, 2016	THOMPSON PETER A.	PURCHASE	12.99	900	11.69K	5.38M
Jun 23, 2016	ORBIMED ADVISORS LLC	PURCHASE	12.92	100	1.29K	5.38M
Jun 23, 2016	THOMPSON PETER A.	PURCHASE	12.92	100	1.29K	5.38M
Jun 21, 2016	ORBIMED ADVISORS LLC	PURCHASE	12.87	26.08K	335.69K	5.38M
Jun 21, 2016	THOMPSON PETER A.	PURCHASE	12.87	26.08K	335.69K	5.38M
Jun 17, 2016	ORBIMED ADVISORS LLC	PURCHASE	12.48	12.3K	153.5K	5.35M
Jun 17, 2016	THOMPSON PETER A.	PURCHASE	12.48	12.3K	153.5K	5.35M
Jun 16, 2016	ORBIMED ADVISORS LLC	PURCHASE	12.04	5K	60.2K	5.34M
Jun 16, 2016	THOMPSON PETER A.	PURCHASE	12.04	5K	60.2K	5.34M
Jun 15, 2016	THOMPSON PETER A.	PURCHASE	11.94	5K	59.7K	5.33M
Jun 15, 2016	ORBIMED ADVISORS LLC	PURCHASE	11.94	5K	59.7K	5.33M
Jun 14, 2016	ORBIMED ADVISORS LLC	PURCHASE	12.71	10K	127.1K	5.33M
Jun 14, 2016	THOMPSON PETER A.	PURCHASE	12.71	10K	127.1K	5.33M
Jun 10, 2016	THOMPSON PETER A.	PURCHASE	12.98	20K	259.6K	5.32M
Jun 10, 2016	ORBIMED ADVISORS LLC	PURCHASE	12.98	20K	259.6K	5.32M
Jun 09, 2016	ORBIMED ADVISORS LLC	PURCHASE	12.95	30K	388.5K	5.3M
Jun 09, 2016	THOMPSON PETER A.	PURCHASE	12.95	30K	388.5K	5.3M
May 20, 2016	ORBIMED ADVISORS LLC	PURCHASE	13.09	4.72K	61.73K	5.27M
May 20, 2016	THOMPSON PETER A.	PURCHASE	13.09	4.72K	61.73K	5.27M
May 19, 2016	THOMPSON PETER A.	PURCHASE	12.75	61	777.75	5.27M
May 19, 2016	ORBIMED ADVISORS LLC	PURCHASE	12.75	61	777.75	5.27M
May 18, 2016	THOMPSON PETER A.	PURCHASE	11.55	4.2K	48.51K	5.26M
May 18, 2016	ORBIMED ADVISORS LLC	PURCHASE	11.55	4.2K	48.51K	5.26M
May 13, 2016	MILLER RICHARD A MD	PURCHASE	9.94	300	2.98K	1.08M
May 12, 2016	NOVO A/S	PURCHASE	10.00	70K	700K	3.22M
May 12, 2016	MILLER RICHARD A MD	PURCHASE	10.00	30K	300K	1.08M
Mar 29, 2016	NOVO A/S	PURCHASE	15.00	666.67K	10M	3.15M

Frequently Asked Questions