How many institutions own CRNX stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own CRNX shares is 325, representing 114.4% of the company's common stock.

Who are the major shareholders selling Crinetics Pharmaceuticals, Inc. stock?

GW&K INVESTMENT MANAGEMENT, LLC, in the last quarter, reduced its stake in CRNX by -12.39% restricting it's holding to 850.55 thousand shares of worth nearly $35.43M. HOOD RIVER CAPITAL MANAGEMENT LLC also lessened -0.62% of the CRNX shares from its portfolio, reducing its holding to 883 thousand shares of worth $36.78M. ENVESTNET ASSET MANAGEMENT INC also shunned CRNX shares holding by -2.94% last quarter which brought its holding to 52.67 thousand shares worth $2.19M.

Investors who are buying CRNX stock?

As per its latest 13F filing, UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH increased its stake in CRNX by 13.53% in the last quarter. The institutional holder raised its holding to 387.93 thousand shares having worth more than $16.16M. RTW INVESTMENTS, LP also added 86.81% more shares of CRNX to its portfolio, raising its holding to 872.39 thousand shares of worth $36.33M. CITADEL ADVISORS LLC also increased its CRNX shares holding by 35.32% which brought its holding to 884.51 thousand shares worth $36.84M.

CRNX's major insiders: who are they?

The insider with the most stakes in CRNX is PERCEPTIVE ADVISORS LLC , 10 percent owner at the company. Additionally, CRNX stock is highly held by EDELMAN JOSEPH and 5AM Ventures IV, L.P. among others.

Did an insider recently sell CRNX stock?

Company executives, directors, and other insiders own 2.01% percent of Crinetics Pharmaceuticals, Inc.'s stock. Within the last six months, there have been 8 transaction(s) in which CRNX insiders have sold stock, totaling 71.59K shares. Insiders that have sold shares include PIZZUTI DANA, STRUTHERS RICHARD SCOTT, and FUST MATTHEW K.

Which insider recently purchased CRNX stock?

There have been 0 transaction(s) during the past 6-months in which Crinetics Pharmaceuticals, Inc. insiders have bought stock, totalling 0 shares

How much of CRNX does insiders own?

Around 557.02K Crinetics Pharmaceuticals, Inc. shares are held by insiders, which represents about 2.01% of CRNX stock.

Who is the insider with the largest stake?

CRNX 10 percent owner, PERCEPTIVE ADVISORS LLC holds the largest portfolio of the company's shares. CRNX shares owned by PERCEPTIVE total nearly 5.32 million.

Which institution holds the most shares in CRNX?

UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH is the largest institutional owner in CRNX which holds 387.93 thousand shares worth $16.16M or 0.41% of the total CRNX shares outstanding followed by GW&K INVESTMENT MANAGEMENT, LLC with ownership of 850.55 thousand shares representing 0.91% of the CRNX ownership. RTW INVESTMENTS, LP is the third largest stakeholder with 872.39 thousand shares or 0.93% of the ownership worth more than $36.33M.

Is Crinetics Pharmaceuticals, Inc. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the CRNX is concerned, it is a stock which is optionable.

Is there a short position on CRNX's shares?

Number of CRNX shares short is 13.90M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding CRNX shares are there?

As of today, 94.18M shares of CRNX are outstanding.

Is there many float in CRNX stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, CRNX has 92.78M shares in float.

CRNX short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for CRNX is 14.63.

Crinetics Pharmaceuticals (CRNX) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares14.76

Short Percent Of Float16.79

Shares Outstanding94.18M

Shares Float92.78M

Shares Short13.90M

Short Ratio14.63

16.79%

Short % of Float

14.76%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

2.01% Percentage of Shares held by All Insiders

114.4% Percentage of Shares held by All Institutions

116.75% Percentage of Float held by Institutions

325

Number of Institutions Holding Shares

Institutional Ownership

About 114.4% of CRNX shares are held by financial institutions. UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH is the top corporate investor, holding 387.93K shares valued at $16.16M. A 0.41% stake in Crinetics Pharmaceuticals, Inc. is owned by the company. GW&K INVESTMENT MANAGEMENT, LLC owns 850.55K shares valued at $35.43M, which translates its holding of 0.91% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Sep 30, 2025	UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH	0.41%	387.93K	16.16M	46.22K	+13.53%
Sep 30, 2025	GW&K INVESTMENT MANAGEMENT, LLC	0.91%	850.55K	35.43M	-120.26K	-12.39%
Sep 30, 2025	RTW INVESTMENTS, LP	0.93%	872.39K	36.33M	405.39K	+86.81%
Sep 30, 2025	HOOD RIVER CAPITAL MANAGEMENT LLC	0.94%	883K	36.78M	-5.47K	-0.62%
Sep 30, 2025	CITADEL ADVISORS LLC	0.94%	884.51K	36.84M	230.87K	+35.32%
Sep 30, 2025	FIRST LIGHT ASSET MANAGEMENT, LLC	1%	941.52K	39.21M	77.38K	+8.95%
Sep 30, 2025	JPMORGAN CHASE & CO	1.34%	1.26M	52.43M	926.77K	+279.18%
Sep 30, 2025	NATIXIS ADVISORS, L.P.	0.06%	51.75K	2.16M	4.63K	+9.83%
Sep 30, 2025	ENVESTNET ASSET MANAGEMENT INC	0.06%	52.67K	2.19M	-1.59K	-2.94%
Sep 30, 2025	SIREN, L.L.C.	1.8%	1.69M	70.33M	0	0
Sep 30, 2025	NOVO HOLDINGS A/S	1.73%	1.63M	67.68M	75K	+4.84%
Sep 30, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.06%	53.41K	2.22M	0	0
Sep 30, 2025	PHOCAS FINANCIAL CORP.	0.06%	54.02K	2.25M	54.02K	+100.00%
Sep 30, 2025	SEI INVESTMENTS CO	0.06%	60.34K	2.51M	160	+0.27%
Sep 30, 2025	NEUBERGER BERMAN GROUP LLC	0.07%	67.15K	2.8M	67.15K	+100.00%
Sep 30, 2025	WINTON GROUP LTD	0.07%	68.2K	2.84M	68.2K	+100.00%
Sep 30, 2025	STATE OF NEW JERSEY COMMON PENSION FUND D	0.08%	72.35K	3.01M	9.8K	+15.66%
Sep 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.08%	75K	3.12M	-77.25K	-50.74%
Sep 30, 2025	PIER CAPITAL, LLC	0.08%	75K	3.12M	-67.61K	-47.41%
Sep 30, 2025	SCHRODER INVESTMENT MANAGEMENT GROUP	0.09%	87.32K	3.8M	-53.66K	-38.06%
Sep 30, 2025	INVESCO LTD.	0.1%	89.39K	3.72M	11.25K	+14.40%
Sep 30, 2025	LEGAL & GENERAL GROUP PLC	0.1%	93.81K	3.91M	-3.72K	-3.82%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0.11%	98.7K	4.11M	8.64K	+9.60%
Sep 30, 2025	AWM INVESTMENT COMPANY, INC.	0.11%	100K	4.17M	5K	+5.26%
Sep 30, 2025	MOODY ALDRICH PARTNERS LLC	0.12%	115.54K	4.81M	-22.25K	-16.15%
Sep 30, 2025	RHUMBLINE ADVISERS	0.14%	131.52K	5.48M	-3.79K	-2.80%
Sep 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.16%	148.28K	6.18M	7.36K	+5.22%
Sep 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0.16%	148.98K	6.21M	-7.4K	-4.73%
Sep 30, 2025	SWISS NATIONAL BANK	0.18%	172.5K	7.18M	3.7K	+2.19%
Sep 30, 2025	RICE HALL JAMES & ASSOCIATES, LLC	0.19%	174.08K	7.25M	174.08K	+100.00%
Sep 30, 2025	SIO CAPITAL MANAGEMENT, LLC	0.19%	174.84K	7.28M	174.84K	+100.00%
Sep 30, 2025	SKANDINAVISKA ENSKILDA BANKEN AB (PUBL)	0.19%	178.58K	7.44M	160.47K	+885.73%
Sep 30, 2025	SEGALL BRYANT & HAMILL, LLC	0.19%	180.85K	7.53M	4.33K	+2.45%
Sep 30, 2025	BARCLAYS PLC	0.2%	183.24K	7.63M	-108.81K	-37.26%
Sep 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	5.66%	5.31M	221.01M	-284.26K	-5.08%
Sep 30, 2025	FARALLON CAPITAL MANAGEMENT LLC	6.15%	5.77M	240.32M	1.12M	+24.19%
Sep 30, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	6.91%	6.48M	269.96M	81.59K	+1.27%
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.43%	399.63K	16.64M	53.71K	+15.53%
Sep 30, 2025	ORBIMED ADVISORS LLC	1.17%	1.1M	45.77M	-50K	-4.35%
Sep 30, 2025	AMERICAN CENTURY COMPANIES INC	1.21%	1.13M	47.21M	284.9K	+33.57%
Sep 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	1.56%	1.47M	61.03M	264.79K	+22.06%
Sep 30, 2025	JANUS HENDERSON GROUP PLC	4.11%	3.86M	160.7M	448.47K	+13.15%
Sep 30, 2025	ECOR1 CAPITAL, LLC	4.57%	4.29M	178.6M	0	0
Sep 30, 2025	BLACKROCK, INC.	8.09%	7.59M	315.98M	167.88K	+2.26%
Sep 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	8.94%	8.38M	349.11M	2.57M	+44.34%
Sep 30, 2025	CHECKPOINT CAPITAL L.P.	0.28%	260K	10.83M	260K	+100.00%
Sep 30, 2025	VANGUARD GROUP INC	9.78%	9.17M	381.94M	-86K	-0.93%
Sep 30, 2025	FMR LLC	15.13%	14.19M	590.91M	61.5K	+0.44%
Sep 30, 2025	TD ASSET MANAGEMENT INC	0.22%	203.55K	8.48M	1.07K	+0.53%
Sep 30, 2025	HSBC HOLDINGS PLC	0.22%	210.82K	8.78M	203.62K	+2,829.29%
Sep 30, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.23%	217.69K	9.07M	-117.11K	-34.98%
Sep 30, 2025	DEUTSCHE BANK AG\	0.25%	232.37K	9.68M	37.17K	+19.04%
Sep 30, 2025	VICTORY CAPITAL MANAGEMENT INC	0.25%	233.39K	9.72M	-28.15K	-10.76%
Sep 30, 2025	UBS GROUP AG	0.43%	407.72K	16.98M	87.18K	+27.20%
Sep 30, 2025	FIERA CAPITAL CORP	0.46%	435.43K	18.14M	-8.91K	-2.00%
Sep 30, 2025	NUVEEN, LLC	0.58%	544.75K	22.69M	19.8K	+3.77%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.64%	601.04K	25.03M	27.76K	+4.84%
Sep 30, 2025	AMERIPRISE FINANCIAL INC	0.66%	614.82K	25.61M	376.21K	+157.67%
Sep 30, 2025	MORGAN STANLEY	0.73%	682.13K	28.41M	-77.89K	-10.25%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	0.76%	713.13K	29.7M	-187.76K	-20.84%
Sep 30, 2025	CANDRIAM S.C.A.	0.79%	745.09K	31.03M	51.23K	+7.38%
Sep 30, 2025	VESTAL POINT CAPITAL, LP	0.8%	750K	31.24M	-750K	-50.00%
Sep 30, 2025	FISHER ASSET MANAGEMENT, LLC	0.81%	758.36K	31.59M	21.27K	+2.89%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.83%	778.65K	32.43M	12.42K	+1.62%
Sep 30, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	0.26%	248.37K	10.34M	195.24K	+367.52%
Sep 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.27%	257.51K	10.73M	129.84K	+101.71%
Sep 30, 2025	IKARIAN CAPITAL, LLC	0.27%	257.7K	10.73M	257.7K	+100.00%
Sep 30, 2025	NORTHERN TRUST CORP	0.86%	809.89K	33.73M	25.68K	+3.27%
Sep 30, 2025	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	0.89%	834.03K	34.74M	121.31K	+17.02%
Sep 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	2.14%	2M	83.44M	5.17K	+0.26%
Sep 30, 2025	JENNISON ASSOCIATES LLC	2.18%	2.04M	85.16M	57.62K	+2.90%
Sep 30, 2025	STATE STREET CORP	2.35%	2.21M	91.95M	-1.02M	-31.53%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.43%	2.28M	94.93M	65.51K	+2.96%
Sep 30, 2025	PARADIGM BIOCAPITAL ADVISORS LP	2.72%	2.55M	106.24M	207.22K	+8.84%
Sep 30, 2025	BAKER BROS. ADVISORS LP	0.3%	280K	11.66M	0	0
Sep 30, 2025	ENSIGN PEAK ADVISORS, INC	0.31%	295.01K	12.29M	-20.56K	-6.51%
Sep 30, 2025	PROSIGHT MANAGEMENT, LP	0.35%	328.68K	13.69M	30.56K	+10.25%
Sep 30, 2025	ABRDN PLC	0.36%	339.95K	14.16M	59.6K	+21.26%
Sep 30, 2025	DIMENSIONAL FUND ADVISORS LP	0.4%	377.8K	15.74M	202.55K	+115.57%
Sep 30, 2025	CORMORANT ASSET MANAGEMENT, LP	0.43%	400K	16.66M	0	0
Jun 30, 2025	UBS GROUP AG	0.34%	320.55K	9.22M	4.89K	+1.55%
Jun 30, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.36%	334.8K	9.63M	-12.79K	-3.68%
Jun 30, 2025	BAKER BROS. ADVISORS LP	0.3%	280K	8.05M	280K	+100.00%
Jun 30, 2025	ABRDN PLC	0.3%	280.35K	8.06M	72.29K	+34.74%
Jun 30, 2025	JPMORGAN CHASE & CO	0.35%	331.96K	9.55M	66.46K	+25.03%
Jun 30, 2025	RTW INVESTMENTS, LP	0.5%	467K	13.43M	467K	+100.00%
Jun 30, 2025		0.36%	341.71K	9.83M	-1.03K	-0.30%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0.61%	573.28K	16.49M	268.36K	+88.01%
Jun 30, 2025	FMR LLC	15.06%	14.13M	406.26M	94.73K	+0.68%
Jun 30, 2025	FISHER ASSET MANAGEMENT, LLC	0.79%	737.08K	21.2M	-36.26K	-4.69%
Jun 30, 2025	HOOD RIVER CAPITAL MANAGEMENT LLC	0.95%	888.47K	25.55M	15.84K	+1.81%
Jun 30, 2025	GW&K INVESTMENT MANAGEMENT, LLC	1.04%	970.81K	27.92M	50.79K	+5.52%
Jun 30, 2025	ORBIMED ADVISORS LLC	1.23%	1.15M	33.05M	150K	+15.02%
Jun 30, 2025	NEOS INVESTMENT MANAGEMENT LLC	0.06%	58.1K	1.67M	-706	-1.20%
Jun 30, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	0.06%	53.13K	1.53M	0	0
Jun 30, 2025	ALPS ADVISORS INC	0.05%	50.52K	1.45M	-16.78K	-24.93%
Jun 30, 2025	NATIXIS ADVISORS, L.P.	0.05%	47.12K	1.36M	606	+1.30%
Jun 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.05%	42.63K	1.23M	-14.32K	-25.14%
Jun 30, 2025	UBS OCONNOR LLC	0.04%	39.98K	1.15M	-635	-1.56%
Jun 30, 2025	XTX TOPCO LTD	0.04%	34.01K	978.21K	34.01K	+100.00%
Jun 30, 2025	TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY	0.03%	27.38K	787K	-1.6K	-5.52%
Jun 30, 2025	ARIZONA STATE RETIREMENT SYSTEM	0.03%	25.8K	741.89K	1.9K	+7.94%
Jun 30, 2025	PARKMAN HEALTHCARE PARTNERS LLC	0.08%	73.41K	2.11M	9.47K	+14.81%
Jun 30, 2025	STATE OF WISCONSIN INVESTMENT BOARD	0.07%	64.59K	1.86M	1.03K	+1.62%
Jun 30, 2025	STATE OF NEW JERSEY COMMON PENSION FUND D	0.07%	62.55K	1.8M	6.67K	+11.94%
Jun 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	1.28%	1.2M	34.53M	153.46K	+14.66%
Jun 30, 2025	VESTAL POINT CAPITAL, LP	1.6%	1.5M	43.14M	0	0
Jun 30, 2025	VANGUARD GROUP INC	9.87%	9.26M	266.21M	-55.47K	-0.60%
Jun 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	6.19%	5.81M	167.02M	-1.08M	-15.73%
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	5.96%	5.59M	160.78M	478.14K	+9.35%
Jun 30, 2025	PARADIGM BIOCAPITAL ADVISORS LP	2.5%	2.34M	67.4M	397.39K	+20.42%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.36%	2.21M	63.66M	22.39K	+1.02%
Jun 30, 2025	JENNISON ASSOCIATES LLC	2.12%	1.99M	57.15M	-132.65K	-6.26%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.96%	900.89K	25.91B	401.29K	+80.32%
Jun 30, 2025	FIRST LIGHT ASSET MANAGEMENT, LLC	0.92%	864.14K	24.85M	8.72K	+1.02%
Jun 30, 2025	AMERICAN CENTURY COMPANIES INC	0.9%	848.64K	24.41M	129.06K	+17.94%
Jun 30, 2025	MORGAN STANLEY	0.81%	760.02K	21.86B	245.34K	+47.67%
Jun 30, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	0.76%	716.17K	20.6M	26.91K	+3.90%
Jun 30, 2025	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	0.76%	712.72K	20.5M	101.88K	+16.68%
Jun 30, 2025	CANDRIAM S.C.A.	0.74%	693.87K	19.96M	204.96K	+41.92%
Jun 30, 2025	CITADEL ADVISORS LLC	0.7%	653.64K	18.8B	615.08K	+1,595.51%
Jun 30, 2025	FRANKLIN RESOURCES INC	0.69%	649.14K	18.67M	-314.14K	-32.61%
Jun 30, 2025	IKARIAN CAPITAL, LLC	0.46%	433.43K	12.47M	-90K	-17.19%
Jun 30, 2025	BIOIMPACT CAPITAL LLC	0.46%	428.98K	12.34M	-202.99K	-32.12%
Jun 30, 2025	CORMORANT ASSET MANAGEMENT, LP	0.43%	400K	11.5M	-200K	-33.33%
Jun 30, 2025	MILLENNIUM MANAGEMENT LLC	0.38%	357.68K	10.29M	350.99K	+5,248.04%
Jun 30, 2025	ENSIGN PEAK ADVISORS, INC	0.34%	315.56K	9.08M	-199.25K	-38.70%
Jun 30, 2025	PROSIGHT MANAGEMENT, LP	0.32%	298.12K	8.57M	298.12K	+100.00%
Jun 30, 2025	BARCLAYS PLC	0.31%	292.05K	8.4M	126.14K	+76.03%
Jun 30, 2025	M&G PLC	0.3%	281.9K	8.17M	74	+0.03%
Jun 30, 2025	NORTHERN TRUST CORP	0.84%	784.21K	22.55M	-72.87K	-8.50%
Jun 30, 2025	BANK OF NEW YORK MELLON CORP	0.37%	345.93K	9.95M	1.35K	+0.39%
Jun 30, 2025	NOVO HOLDINGS A/S	1.65%	1.55M	44.58M	275K	+21.57%
Jun 30, 2025	SIREN, L.L.C.	1.8%	1.69M	48.56M	0	0
Jun 30, 2025	UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH	0.36%	341.71K	9.83M	-1.03K	-0.30%
Jun 30, 2025	NUVEEN, LLC	0.56%	524.95K	15.1M	-37.98K	-6.75%
Jun 30, 2025	SEGALL BRYANT & HAMILL, LLC	0.19%	176.52K	5.08M	30.24K	+20.68%
Jun 30, 2025	WALLEYE CAPITAL LLC	0.2%	190.37K	5.48M	66.39K	+53.55%
Jun 30, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.21%	198.92K	5.72M	-230.15K	-53.64%
Jun 30, 2025	TD ASSET MANAGEMENT INC	0.22%	202.48K	5.82M	27.79K	+15.91%
Jun 30, 2025	STATE STREET CORP	3.44%	3.22M	92.73M	-58.97K	-1.80%
Jun 30, 2025	ALLIANCEBERNSTEIN L.P.	0.1%	93.02K	2.68B	-17.65K	-15.95%
Jun 30, 2025	AWM INVESTMENT COMPANY, INC.	0.1%	95K	2.73M	0	0
Jun 30, 2025	VERITION FUND MANAGEMENT LLC	0.1%	95.33K	2.74M	68.88K	+260.32%
Jun 30, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.12%	108.97K	3.13M	-31K	-22.15%
Jun 30, 2025	MOODY ALDRICH PARTNERS LLC	0.15%	137.8K	3.96M	-2.11K	-1.51%
Jun 30, 2025	SCHRODER INVESTMENT MANAGEMENT GROUP	0.15%	140.98K	4.05M	63.52K	+82.00%
Jun 30, 2025	NEW LEAF VENTURE PARTNERS, L.L.C.	0.15%	141K	4.06M	0	0
Jun 30, 2025	PIER CAPITAL, LLC	0.15%	142.61K	4.1M	29.2K	+25.75%
Jun 30, 2025	DECHENG CAPITAL LLC	0.15%	143K	4.11M	-34.96K	-19.64%
Jun 30, 2025	SCHONFELD STRATEGIC ADVISORS LLC	0.16%	147.92K	4.25M	128.73K	+670.75%
Jun 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.16%	152.25K	4.38M	0	0
Jun 30, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.1%	90.76K	2.61M	-11.38K	-11.14%
Jun 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	2.13%	2M	57.47M	1.22M	+156.70%
Jun 30, 2025	FARALLON CAPITAL MANAGEMENT LLC	4.95%	4.65M	133.62M	41K	+0.89%
Jun 30, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	6.82%	6.4M	184.06M	160.12K	+2.57%
Jun 30, 2025	BLACKROCK, INC.	7.91%	7.42M	213.36M	-237.85K	-3.11%
Jun 30, 2025	ROYAL BANK OF CANADA	0.18%	172.48K	4.96M	145.74K	+545.12%
Jun 30, 2025	JANUS HENDERSON GROUP PLC	3.64%	3.41M	98.06M	-14.12K	-0.41%
Jun 30, 2025	ECOR1 CAPITAL, LLC	4.57%	4.29M	123.33M	0	0
Jun 30, 2025	FIERA CAPITAL CORP	0.47%	444.33K	12.78M	5.99K	+1.37%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.82%	766.23K	22.04M	12.7K	+1.69%
Jun 30, 2025	VICTORY CAPITAL MANAGEMENT INC	0.28%	261.53K	7.52M	10.2K	+4.06%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.81%	753.53K	25.27M	-5.6K	-0.74%
Mar 31, 2025	FARALLON CAPITAL MANAGEMENT LLC	4.95%	4.61M	154.45M	530K	+13.01%
Mar 31, 2025	JANUS HENDERSON GROUP PLC	3.68%	3.42M	118.9M	629K	+22.50%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.54%	499.59K	16.76M	-221.68K	-30.73%
Mar 31, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.46%	429.06K	14.39M	209.54K	+95.45%
Mar 31, 2025	NORTHERN TRUST CORP	0.92%	857.08K	28.75M	-22.73K	-2.58%
Mar 31, 2025	CORMORANT ASSET MANAGEMENT, LP	0.64%	600K	20.12M	-400K	-40.00%
Mar 31, 2025	JENNISON ASSOCIATES LLC	2.28%	2.12M	71.1M	-588.58K	-21.73%
Mar 31, 2025	FMR LLC	15.07%	14.03M	470.61M	5.1M	+57.16%
Mar 31, 2025	VANGUARD GROUP INC	10%	9.31M	312.31M	222.21K	+2.44%
Mar 31, 2025	BLACKROCK, INC.	8.22%	7.66M	256.8M	141.38K	+1.88%
Mar 31, 2025	STATE STREET CORP	3.53%	3.28M	110.12M	292.44K	+9.78%
Mar 31, 2025	VESTAL POINT CAPITAL, LP	1.61%	1.5M	50.31M	1.5M	+100.00%
Mar 31, 2025	NOVO HOLDINGS A/S	1.37%	1.28M	42.76M	314.79K	+32.78%
Mar 31, 2025	PICTET ASSET MANAGEMENT HOLDING SA	1.12%	1.05M	35.12M	198.97K	+23.46%
Mar 31, 2025	ORBIMED ADVISORS LLC	1.07%	999K	33.51M	0	0
Mar 31, 2025	FRANKLIN RESOURCES INC	1.03%	963.28K	32.31M	-628.39K	-39.48%
Mar 31, 2025	FIRST LIGHT ASSET MANAGEMENT, LLC	0.92%	855.42K	28.69M	-30.03K	-3.39%
Mar 31, 2025	AMERICAN CENTURY COMPANIES INC	0.77%	719.58K	24.13M	242.28K	+50.76%
Mar 31, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	0.74%	689.27K	23.12M	-313.62K	-31.27%
Mar 31, 2025	BIOIMPACT CAPITAL LLC	0.68%	631.96K	21.2M	14.93K	+2.42%
Mar 31, 2025	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	0.66%	610.84K	20.49M	34.77K	+6.04%
Mar 31, 2025	IKARIAN CAPITAL, LLC	0.56%	523.43K	17.56M	7K	+1.36%
Mar 31, 2025	SG AMERICAS SECURITIES, LLC	0.56%	522.27K	17.52M	-20.18K	-3.72%
Mar 31, 2025	MORGAN STANLEY	0.55%	514.68K	17.26M	9.64K	+1.91%
Mar 31, 2025	CANDRIAM S.C.A.	0.53%	488.91K	16.4M	488.91K	+100.00%
Mar 31, 2025	FIERA CAPITAL CORP	0.47%	438.34K	14.7M	-16.65K	-3.66%
Mar 31, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.39%	358.54K	12.03M	-30.69K	-7.88%
Mar 31, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.37%	347.58K	11.66M	22.31K	+6.86%
Mar 31, 2025	BANK OF NEW YORK MELLON CORP	0.37%	344.58K	11.56M	-186	-0.05%
Mar 31, 2025		0.37%	342.73K	11.5M	7.95K	+2.38%
Mar 31, 2025	UBS GROUP AG	0.34%	315.66K	10.59M	-392.07K	-55.40%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0.33%	304.93K	10.23M	69.65K	+29.60%
Mar 31, 2025	JPMORGAN CHASE & CO	0.29%	265.5K	8.9M	-4.05K	-1.50%
Mar 31, 2025	VICTORY CAPITAL MANAGEMENT INC	0.27%	251.33K	8.43M	-30.12K	-10.70%
Mar 31, 2025	PRUDENTIAL FINANCIAL INC	0.26%	242.88K	8.28M	-34.5K	-12.44%
Mar 31, 2025	ABRDN PLC	0.22%	208.06K	6.98M	164.67K	+379.52%
Mar 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	7.4%	6.89M	231.14M	-59.17K	-0.85%
Mar 31, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	6.7%	6.24M	209.29M	98.89K	+1.61%
Mar 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	5.49%	5.11M	171.47M	-302.15K	-5.58%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.35%	2.19M	73.5M	92.09K	+4.39%
Mar 31, 2025	PARADIGM BIOCAPITAL ADVISORS LP	2.09%	1.95M	65.27M	35.41K	+1.85%
Mar 31, 2025	SIREN, L.L.C.	1.81%	1.69M	56.64M	78.96K	+4.91%
Mar 31, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.84%	778.4K	26.11M	-2.01M	-72.09%
Mar 31, 2025	FISHER ASSET MANAGEMENT, LLC	0.83%	773.35K	25.94M	214.06K	+38.27%
Mar 31, 2025	ENSIGN PEAK ADVISORS, INC	0.55%	514.81K	17.27M	12.12K	+2.41%
Mar 31, 2025	GW&K INVESTMENT MANAGEMENT, LLC	0.99%	920.02K	30.86M	240.9K	+35.47%
Mar 31, 2025	HOOD RIVER CAPITAL MANAGEMENT LLC	0.94%	872.64K	29.27M	21.24K	+2.49%
Mar 31, 2025	M&G PLC	0.3%	281.82K	9.58M	281.82K	+100.00%
Mar 31, 2024	JPMORGAN CHASE & CO	0.56%	375.99K	17.6M	282.88K	+303.83%
Mar 31, 2024	BIOIMPACT CAPITAL LLC	0.72%	480.59K	22.5M	2.35K	+0.49%
Mar 31, 2024	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	0.81%	542.71K	25.4M	-115.58K	-17.56%
Mar 31, 2024	STATE STREET CORP	4.85%	3.26M	152.38M	-308.48K	-8.66%
Mar 31, 2024	VANGUARD GROUP INC	5.32%	3.58M	167.35M	72.62K	+2.07%
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	5.69%	3.82M	178.97M	814.36K	+27.07%
Mar 31, 2024	ECOR1 CAPITAL, LLC	6.19%	4.16M	194.51M	2.14M	+106.48%
Mar 31, 2024	FMR LLC	6.65%	4.46M	208.94M	419.81K	+10.38%
Mar 31, 2024	POINT72 ASSET MANAGEMENT, L.P.	7.37%	4.95M	231.69M	1.53M	+44.85%
Mar 31, 2024	DRIEHAUS CAPITAL MANAGEMENT LLC	7.78%	5.23M	244.64M	186.34K	+3.70%
Mar 31, 2024	BLACKROCK INC.	8.1%	5.44M	254.46M	90.99K	+1.70%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.82%	553.74K	25.91M	-125.43K	-18.47%
Mar 31, 2024	NORTHERN TRUST CORP	0.9%	601.38K	28.15M	-1.04K	-0.17%
Mar 31, 2024	MORGAN STANLEY	0.91%	612.2K	28.66M	-36.05K	-5.56%
Mar 31, 2024	STEMPOINT CAPITAL LP	0.92%	619.79K	29.01M	370.21K	+148.34%
Mar 31, 2024	ENSIGN PEAK ADVISORS, INC	0.93%	621.51K	29.09M	185.82K	+42.65%
Mar 31, 2024	LAURION CAPITAL MANAGEMENT LP	0.94%	630.18K	29.5M	61.2K	+10.76%
Mar 31, 2024	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.94%	632.13K	29.59M	632.13K	+100.00%
Mar 31, 2024	DIMENSIONAL FUND ADVISORS LP	0.95%	640.8K	30M	-19.12K	-2.90%
Mar 31, 2024	SATURN V CAPITAL MANAGEMENT LLC	0.98%	660.14K	30.9M	-126.99K	-16.13%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	1.29%	864.11K	40.45M	213.93K	+32.90%
Mar 31, 2024	LORD, ABBETT & CO. LLC	1.44%	964.57K	45.15M	187.28K	+24.09%
Mar 31, 2024	ROCK SPRINGS CAPITAL MANAGEMENT LP	0.43%	289.4K	13.55M	289.4K	+100.00%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.44%	296.48K	13.88M	-33.1K	-10.04%
Mar 31, 2024	IKARIAN CAPITAL, LLC	0.45%	300.4K	14.06M	300.4K	+100.00%
Mar 31, 2024	DUQUESNE FAMILY OFFICE LLC	0.46%	309K	14.46M	309K	+100.00%
Mar 31, 2024	CAPTION MANAGEMENT, LLC	0.48%	319K	14.93M	243.8K	+324.20%
Mar 31, 2024	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.48%	325K	15.21M	125K	+62.50%
Mar 31, 2024	VIVO CAPITAL, LLC	0.52%	350K	16.38M	0	0
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.53%	357.14K	16.72M	12.73K	+3.70%
Mar 31, 2024	GW&K INVESTMENT MANAGEMENT, LLC	0.58%	388.07K	18.17M	-91K	-18.99%
Mar 31, 2024	FRANKLIN RESOURCES INC	0.62%	413.21K	19.34M	0	0
Mar 31, 2024	FISHER ASSET MANAGEMENT, LLC	0.65%	436.02K	20.41M	-5.27K	-1.19%
Mar 31, 2024	AFFINITY ASSET ADVISORS, LLC	0.7%	470K	22M	22.91K	+5.12%
Mar 31, 2024	FIERA CAPITAL CORP	0.71%	475.51K	22.26M	475.51K	+100.00%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.71%	478.53K	22.4M	8.16K	+1.73%
Mar 31, 2024	EVENTIDE ASSET MANAGEMENT, LLC	1.58%	1.06M	49.6M	0	0
Mar 31, 2024	NOVO HOLDINGS A/S	1.64%	1.1M	51.43M	-1.4K	-0.13%
Mar 31, 2024	CORMORANT ASSET MANAGEMENT, LP	1.71%	1.15M	53.83M	0	0
Mar 31, 2024	ORBIMED ADVISORS LLC	2.06%	1.39M	64.83M	-282.36K	-16.93%
Mar 31, 2024	ARTAL GROUP S.A.	2.07%	1.39M	65.09M	1.39M	+100.00%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	2.09%	1.4M	65.61M	48.73K	+3.60%
Mar 31, 2024	PERCEPTIVE ADVISORS LLC	2.2%	1.48M	69.1M	220.69K	+17.58%
Mar 31, 2024	FIRST LIGHT ASSET MANAGEMENT, LLC	2.52%	1.69M	79.12M	-297.6K	-14.97%
Mar 31, 2024	JANUS HENDERSON GROUP PLC	2.95%	1.98M	92.53M	1.43M	+264.13%
Mar 31, 2024	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	3.95%	2.65M	124.27M	237.24K	+9.81%
Mar 31, 2024	JENNISON ASSOCIATES LLC	4.2%	2.82M	131.9M	270.17K	+10.60%
Mar 31, 2024	WELLINGTON MANAGEMENT GROUP LLP	4.43%	2.97M	139.1M	-273.52K	-8.43%
Mar 31, 2024	PARADIGM BIOCAPITAL ADVISORS LP	4.65%	3.12M	146.27M	811.83K	+35.10%
Mar 31, 2024	LEGAL & GENERAL GROUP PLC	0.1%	63.95K	2.99B	9.85K	+18.20%
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	0.1%	67.27K	3.15M	0	0
Mar 31, 2024	WELLS FARGO & COMPANY/MN	0.1%	68.84K	3.22M	47.9K	+228.72%
Mar 31, 2024	LISANTI CAPITAL GROWTH, LLC	0.1%	69.23K	3.24M	-31.02K	-30.94%
Mar 31, 2024	STATE OF NEW JERSEY COMMON PENSION FUND D	0.11%	72.1K	3.38M	72.1K	+100.00%
Mar 31, 2024	CANDRIAM S.C.A.	0.13%	88.01K	4.12M	-200.01K	-69.44%
Mar 31, 2024	QUBE RESEARCH & TECHNOLOGIES LTD	0.14%	94.87K	4.44M	37.15K	+64.37%
Mar 31, 2024	ABRDN PLC	0.15%	101.2K	4.74M	0	0
Mar 31, 2024	FIRST TRUST ADVISORS LP	0.15%	101.74K	4.76M	28.28K	+38.50%
Mar 31, 2024	EAM INVESTORS, LLC	0.16%	106.61K	4.99M	1.61K	+1.53%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.16%	107.67K	5.04M	26.7K	+32.98%
Mar 31, 2024	RHUMBLINE ADVISERS	0.16%	108.69K	5.09M	1.48K	+1.38%
Mar 31, 2024	PIER CAPITAL, LLC	0.17%	116.57K	5.46M	-33	-0.03%
Mar 31, 2024	SWISS NATIONAL BANK	0.19%	126.5K	5.92M	22.3K	+21.40%
Mar 31, 2024	SILVERARC CAPITAL MANAGEMENT, LLC	0.19%	127.84K	5.98M	127.84K	+100.00%
Mar 31, 2024	NEW LEAF VENTURE PARTNERS, L.L.C.	0.21%	141K	6.6M	0	0
Mar 31, 2024	PRUDENTIAL FINANCIAL INC	0.22%	144.63K	6.77M	7.69K	+5.61%
Mar 31, 2024	NEW YORK STATE COMMON RETIREMENT FUND	0.23%	152.49K	7.14M	124.77K	+450.02%
Mar 31, 2024	DECHENG CAPITAL LLC	0.24%	157.96K	7.39M	157.96K	+100.00%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.26%	176.2K	8.25M	176.2K	+100.00%
Mar 31, 2024	INVESCO LTD.	0.26%	176.94K	8.28M	5.11K	+2.97%
Mar 31, 2024	RAFFERTY ASSET MANAGEMENT, LLC	0.32%	216.85K	10.15M	-27.44K	-11.23%
Mar 31, 2024	TD ASSET MANAGEMENT INC	0.35%	235.2K	11.01B	58.77K	+33.31%
Mar 31, 2024	UBS GROUP AG	0.37%	247.8K	11.6M	109.34K	+78.96%
Mar 31, 2024	CITIGROUP INC	0.37%	248.05K	11.61M	145.74K	+142.45%
Mar 31, 2024	VICTORY CAPITAL MANAGEMENT INC	0.38%	257.15K	12.04M	73.04K	+39.67%
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	5.3%	3.01M	107.06M	430.66K	+16.70%
Dec 31, 2023	POINT72 ASSET MANAGEMENT, L.P.	6.01%	3.42M	121.57M	-808.4K	-19.13%
Dec 31, 2023	VANGUARD GROUP INC	6.17%	3.5M	124.62M	95.42K	+2.80%
Dec 31, 2023	STATE STREET CORP	6.27%	3.56M	126.8M	711.02K	+24.92%
Dec 31, 2023	WELLINGTON MANAGEMENT GROUP LLP	5.71%	3.25M	115.46M	3.25M	+100.00%
Dec 31, 2023	FMR LLC	7.12%	4.04M	143.88M	1.9M	+88.89%
Dec 31, 2023	DRIEHAUS CAPITAL MANAGEMENT LLC	8.87%	5.04M	179.32M	-92.33K	-1.80%
Dec 31, 2023	BLACKROCK INC.	9.41%	5.35M	190.18M	499.4K	+10.31%
Dec 31, 2023	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.35%	200K	7.12M	0	0
Dec 31, 2023	RAFFERTY ASSET MANAGEMENT, LLC	0.43%	244.29K	8.69M	46.55K	+23.54%
Dec 31, 2023		0.44%	249.58K	8.88M	249.58K	+100.00%
Dec 31, 2023	WALLEYE CAPITAL LLC	0.47%	269.09K	9.57M	-165.82K	-38.13%
Dec 31, 2023	CANDRIAM S.C.A.	0.51%	288.01K	10.25M	288.01K	+100.00%
Dec 31, 2023	OPALEYE MANAGEMENT INC.	0.54%	307.5K	10.94M	-62.5K	-16.89%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.58%	329.58K	11.73M	-162.47K	-33.02%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.61%	344.41K	12.25M	189.51K	+122.35%
Dec 31, 2023	VIVO CAPITAL, LLC	0.62%	350K	12.45M	0	0
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	0.66%	373.63K	13.29M	91.03K	+32.21%
Dec 31, 2023	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	0.7%	397.48K	14.14M	-1.19M	-75.00%
Dec 31, 2023	FRANKLIN RESOURCES INC	0.73%	413.21K	14.7M	274.38K	+197.65%
Dec 31, 2023	ENSIGN PEAK ADVISORS, INC	0.77%	435.69K	15.5M	51K	+13.26%
Dec 31, 2023	FISHER ASSET MANAGEMENT, LLC	0.78%	441.3K	15.7M	387.44K	+719.34%
Dec 31, 2023	AFFINITY ASSET ADVISORS, LLC	0.79%	447.1K	15.91M	-2.91K	-0.65%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.83%	470.37K	16.74M	9.07K	+1.97%
Dec 31, 2023	BIOIMPACT CAPITAL LLC	0.84%	478.23K	17.02M	-819	-0.17%
Dec 31, 2023	GW&K INVESTMENT MANAGEMENT, LLC	0.84%	479.06K	17.05M	-3.88K	-0.80%
Dec 31, 2023	AVIDITY PARTNERS MANAGEMENT LP	0.93%	529K	18.82M	-81K	-13.28%
Dec 31, 2023	JANUS HENDERSON GROUP PLC	0.96%	543.26K	19.33M	-45.12K	-7.67%
Dec 31, 2023	LAURION CAPITAL MANAGEMENT LP	1%	568.98K	20.24M	222.35K	+64.14%
Dec 31, 2023	NORTHERN TRUST CORP	1.06%	602.42K	21.43M	5.1K	+0.85%
Dec 31, 2023	MORGAN STANLEY	1.14%	648.25K	23.06M	136.93K	+26.78%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	1.14%	650.17K	23.13M	97.58K	+17.66%
Dec 31, 2023	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	1.16%	658.29K	23.42M	24.93K	+3.94%
Dec 31, 2023	DIMENSIONAL FUND ADVISORS LP	1.16%	659.92K	23.48M	-84.9K	-11.40%
Dec 31, 2023	NUVEEN ASSET MANAGEMENT, LLC	1.2%	679.17K	24.16M	268.23K	+65.27%
Dec 31, 2023	IKARIAN CAPITAL, LLC	1.2%	680.37K	24.21M	-112.55K	-14.19%
Dec 31, 2023	LORD, ABBETT & CO. LLC	1.37%	777.29K	27.66M	777.29K	+100.00%
Dec 31, 2023	SATURN V CAPITAL MANAGEMENT LLC	1.39%	787.13K	28.01M	-339.45K	-30.13%
Dec 31, 2023	EVENTIDE ASSET MANAGEMENT, LLC	1.87%	1.06M	37.7M	40.85K	+4.01%
Dec 31, 2023	NOVO HOLDINGS A/S	1.94%	1.1M	39.14M	0	0
Dec 31, 2023	CORMORANT ASSET MANAGEMENT, LP	2.02%	1.15M	40.92M	48.1K	+4.36%
Dec 31, 2023	PERCEPTIVE ADVISORS LLC	2.21%	1.26M	44.67M	-8.22K	-0.65%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	2.38%	1.35M	48.13M	83K	+6.54%
Dec 31, 2023	ORBIMED ADVISORS LLC	2.94%	1.67M	59.32M	-1.23M	-42.43%
Dec 31, 2023	FIRST LIGHT ASSET MANAGEMENT, LLC	3.5%	1.99M	70.72M	404.44K	+25.54%
Dec 31, 2023	ECOR1 CAPITAL, LLC	3.54%	2.01M	71.61M	482.25K	+31.51%
Dec 31, 2023	PARADIGM BIOCAPITAL ADVISORS LP	4.07%	2.31M	82.29M	134.18K	+6.16%
Dec 31, 2023	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	4.26%	2.42M	86.02M	776.8K	+47.35%
Dec 31, 2023	JENNISON ASSOCIATES LLC	4.48%	2.55M	90.65M	1.11M	+77.70%

Insiders

Among the CRNX insiders holding of 2.01% of the stake in company, PERCEPTIVE ADVISORS LLC, 10 percent owner, holds the largest shares of 5.32M. EDELMAN JOSEPH, , is the second largest CRNX insider with ownership of 5.32M shares. 5AM VENTURES IV, L.P., , stands third with possession of 2.27M shares of that stake.

Insiders	Designation	Shares Held
PERCEPTIVE ADVISORS LLC	10 percent owner	5.32M
EDELMAN JOSEPH		5.32M
5AM VENTURES IV, L.P.		2.27M
VIVO CAPITAL VIII, LLC	10 percent owner	2.16M
MADAN AJAY	Chief Development Officer	177K
WILSON MARC	CFO	111.09K
STRUTHERS RICHARD SCOTT	President & CEO	106K
BETZ STEPHEN F.	Chief Scientific Officer	99.71K
KNIGHT JEFF E.	Chief Operating Officer	87.49K
PIZZUTI DANA	Chief Med and Dev Officer	66.84K
KRASNER ALAN SETH	Chief Medical Officer	43.21K
HASSARD JAMES	Chief Commercial Officer	29.26K
FUST MATTHEW K	director	22.84K
OKEY STEPHANIE	director	6K
VIVALDI COELHO ROGERIO	director	5K

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Dec 01, 2025	PIZZUTI DANA	SALE	45.02	5K	225.1K	66.84K
Nov 03, 2025	PIZZUTI DANA	SALE	43.27	100	4.33K	66.27K
Oct 01, 2025	PIZZUTI DANA	SALE	41.81	5K	209.05K	66.27K
Sep 26, 2025	STRUTHERS RICHARD SCOTT	SALE	45.00	4K	180K	106K
Sep 26, 2025	FUST MATTHEW K	SALE	44.75	16K	716K	22.84K
Sep 02, 2025	PIZZUTI DANA	SALE	32.10	5K	160.5K	96.27K
Aug 22, 2025	PIZZUTI DANA	SALE	30.43	30K	912.9K	66.27K
Aug 20, 2025	PIZZUTI DANA	SALE	29.18	6.49K	189.44K	66.27K
Jun 12, 2025	BETZ STEPHEN F.	SALE	32.23	97.48K	3.14M	99.71K
Mar 19, 2025	STRUTHERS RICHARD SCOTT	SALE	34.83	875	30.48K	329.15K
Mar 19, 2025	KNIGHT JEFF E.	SALE	34.83	361	12.57K	87.49K
Mar 19, 2025	BETZ STEPHEN F.	SALE	34.83	291	10.14K	108.59K
Mar 19, 2025	PIZZUTI DANA	SALE	34.83	127	4.42K	72.23K
Feb 03, 2025	PIZZUTI DANA	SALE	39.07	5K	195.35K	31.75K
Jan 03, 2025	PIZZUTI DANA	SALE	52.09	15K	781.35K	29.25K
Dec 02, 2024	STRUTHERS RICHARD SCOTT	SALE	57.57	10K	575.7K	100K
Nov 22, 2024	KNIGHT JEFF E.	SALE	56.52	501	28.32K	51.65K
Oct 03, 2024	PIZZUTI DANA	SALE	54.63	14.38K	785.31K	28.51K
Sep 26, 2024	WILSON MARC	SALE	51.11	25K	1.28M	111.09K
Sep 10, 2024	BETZ STEPHEN F.	SALE	51.50	1.04K	53.3K	68.58K
Aug 26, 2024	BETZ STEPHEN F.	SALE	53.19	3K	159.57K	69.61K
Aug 12, 2024	BETZ STEPHEN F.	SALE	47.68	3K	143.04K	72.61K
Jul 25, 2024	WILSON MARC	SALE	53.88	19.06K	1.03M	111.09K
Jul 25, 2024	BETZ STEPHEN F.	SALE	53.43	3K	160.29K	75.61K
Jul 15, 2024	WILSON MARC	SALE	55.00	25K	1.38M	111.09K
Jul 15, 2024	KNIGHT JEFF E.	SALE	55.00	27K	1.49M	51.65K
Jul 10, 2024	BETZ STEPHEN F.	SALE	48.55	3K	145.65K	78.61K
Jul 05, 2024	HASSARD JAMES	SALE	44.08	15K	661.2K	29.26K
Jul 03, 2024	PIZZUTI DANA	SALE	44.87	14.38K	645.01K	28.51K
Jun 28, 2024	WILSON MARC	SALE	43.61	32.13K	1.4M	111.09K
Jun 26, 2024	KNIGHT JEFF E.	SALE	44.38	956	42.43K	52.58K
Jun 25, 2024	BETZ STEPHEN F.	SALE	45.37	3K	136.11K	80.64K
Jun 24, 2024	PIZZUTI DANA	SALE	45.73	9.5K	434.44K	27.79K
Jun 21, 2024	HASSARD JAMES	SALE	44.66	15K	669.9K	29.26K
Jun 10, 2024	BETZ STEPHEN F.	SALE	43.86	3K	131.58K	83.64K
May 28, 2024	BETZ STEPHEN F.	SALE	47.49	3K	142.47K	86.64K
May 10, 2024	BETZ STEPHEN F.	SALE	49.43	3K	148.29K	89.64K
May 08, 2024	STRUTHERS RICHARD SCOTT	SALE	49.40	107.45K	5.31M	257.49K
Apr 15, 2024	PIZZUTI DANA	SALE	44.47	14.38K	639.26K	27.79K
Apr 04, 2024	STRUTHERS RICHARD SCOTT	SALE	49.17	40.95K	2.01M	237.84K
Mar 28, 2024	OKEY STEPHANIE	SALE	46.38	17.5K	811.65K	6K
Mar 22, 2024	KNIGHT JEFF E.	SALE	45.39	2.36K	107.08K	52.58K
Mar 20, 2024	FUST MATTHEW K	SALE	45.50	17.5K	796.25K	18.54K
Mar 20, 2024	PIZZUTI DANA	SALE	43.69	714	31.19K	27.79K
Mar 19, 2024	WILSON MARC	SALE	42.91	6.94K	297.88K	110.63K
Jan 25, 2024	BETZ STEPHEN F.	SALE	37.26	3K	111.78K	73.3K
Jan 10, 2024	BETZ STEPHEN F.	SALE	37.65	3K	112.95K	76.3K
Jan 03, 2024	PIZZUTI DANA	SALE	35.00	14.38K	503.13K	5.91K
Jan 02, 2024	WILSON MARC	SALE	35.47	10K	354.7K	96.06K
Dec 26, 2023	BETZ STEPHEN F.	SALE	35.89	3K	107.67K	79.3K
Dec 21, 2023	PIZZUTI DANA	SALE	34.57	9.58K	331.28K	5.91K
Dec 11, 2023	BETZ STEPHEN F.	SALE	32.87	3K	98.61K	82.3K
Nov 27, 2023	BETZ STEPHEN F.	SALE	31.84	3K	95.52K	85.3K
Nov 03, 2023	STRUTHERS RICHARD SCOTT	SALE	30.56	199.08K	6.08M	135.52K
Nov 02, 2023	STRUTHERS RICHARD SCOTT	SALE	29.95	918	27.49K	135.52K
Nov 01, 2023	WILSON MARC	SALE	28.75	10K	287.5K	95.6K
Oct 17, 2023	KRASNER ALAN SETH	SALE	30.00	7K	210K	43.21K
Jul 13, 2023	STRUTHERS RICHARD SCOTT	SALE	20.35	14.16K	288.09K	630.81K
Jul 12, 2023	STRUTHERS RICHARD SCOTT	SALE	20.17	11.46K	231.13K	644.96K
Jul 11, 2023	STRUTHERS RICHARD SCOTT	SALE	20.14	24.38K	491.09K	656.42K
Jun 20, 2023	WILSON MARC	SALE	19.97	20K	399.4K	95.16K
Jun 16, 2023	STRUTHERS RICHARD SCOTT	SALE	20.81	50K	1.04M	680.81K
Jun 08, 2023	VIVALDI COELHO ROGERIO	PURCHASE	22.06	5K	110.3K	5K
Apr 05, 2023	PIZZUTI DANA	SALE	16.15	8.21K	132.62K	4.5K
Feb 01, 2023	BETZ STEPHEN F.	SALE	19.59	3.13K	61.24K	64.69K
Jan 25, 2023	BETZ STEPHEN F.	SALE	21.07	8.34K	175.64K	67.82K
Jan 17, 2023	BETZ STEPHEN F.	SALE	18.00	3.13K	56.27K	76.15K
Jan 03, 2023	BETZ STEPHEN F.	SALE	18.35	3.13K	57.36K	79.28K
Dec 15, 2022	BETZ STEPHEN F.	SALE	16.00	3.13K	50.02K	82.4K
Dec 01, 2022	BETZ STEPHEN F.	SALE	17.84	3.13K	55.77K	84.97K
Nov 15, 2022	BETZ STEPHEN F.	SALE	18.72	3.13K	58.52K	88.09K
Nov 01, 2022	BETZ STEPHEN F.	SALE	18.52	3.13K	57.89K	91.22K
Oct 17, 2022	BETZ STEPHEN F.	SALE	17.73	3.13K	55.42K	94.35K
Oct 03, 2022	BETZ STEPHEN F.	SALE	19.64	3.13K	61.39K	97.47K
Sep 15, 2022	BETZ STEPHEN F.	SALE	21.01	4.17K	87.57K	100.6K
Sep 07, 2022	BETZ STEPHEN F.	SALE	21.00	1.04K	21.88K	104.77K
Sep 01, 2022	BETZ STEPHEN F.	SALE	18.59	3.13K	58.11K	105.81K
Jul 26, 2022	KNIGHT JEFF E.	SALE	20.70	1.15K	23.85K	4.95K
Jul 13, 2022	FUST MATTHEW K	SALE	20.96	5.7K	119.45K	12.54K
May 02, 2022	BETZ STEPHEN F.	SALE	20.10	3.25K	65.25K	107.6K
Apr 18, 2022	BETZ STEPHEN F.	SALE	25.81	5.66K	146.19K	110.85K
Apr 18, 2022	PERCEPTIVE ADVISORS LLC	PURCHASE	22.22	157.52K	3.5M	5.32M
Apr 18, 2022	EDELMAN JOSEPH	PURCHASE	22.22	157.52K	3.5M	5.32M
Apr 13, 2022	STRUTHERS RICHARD SCOTT	SALE	27.53	69.18K	1.9M	730.81K
Apr 05, 2022	STRUTHERS RICHARD SCOTT	SALE	25.34	21.36K	541.22K	869.45K
Apr 04, 2022	BETZ STEPHEN F.	SALE	23.97	9K	215.76K	116.51K
Mar 31, 2022	BETZ STEPHEN F.	SALE	21.06	4.16K	87.7K	129.67K
Mar 15, 2022	BETZ STEPHEN F.	SALE	18.94	3.12K	59.15K	133.84K
Mar 01, 2022	MADAN AJAY	SALE	19.88	9K	178.92K	177K
Mar 01, 2022	BETZ STEPHEN F.	SALE	19.73	3.12K	61.62K	136.96K
Feb 15, 2022	BETZ STEPHEN F.	SALE	18.64	3.12K	58.21K	123.58K
Feb 07, 2022	MADAN AJAY	SALE	17.83	13.41K	239.08K	172.05K
Feb 01, 2022	BETZ STEPHEN F.	SALE	18.79	3.12K	58.68K	126.71K
Jan 19, 2022	KRASNER ALAN SETH	SALE	21.21	6.7K	142.08K	8.31K
Jan 18, 2022	BETZ STEPHEN F.	SALE	23.29	4.17K	97.07K	128.88K
Jan 03, 2022	BETZ STEPHEN F.	SALE	28.02	7.17K	200.85K	133.04K
Dec 28, 2021	BETZ STEPHEN F.	SALE	27.95	3K	83.85K	140.21K
Dec 15, 2021	BETZ STEPHEN F.	SALE	24.14	5.67K	136.83K	143.21K
Dec 01, 2021	BETZ STEPHEN F.	SALE	27.38	5.67K	155.19K	148.88K
Nov 16, 2021	BETZ STEPHEN F.	SALE	27.97	1.5K	41.96K	154.55K
Nov 15, 2021	BETZ STEPHEN F.	SALE	26.75	5.67K	151.62K	156.05K
Nov 08, 2021	BETZ STEPHEN F.	SALE	28.42	3.9K	110.85K	161.72K
Nov 05, 2021	BETZ STEPHEN F.	SALE	27.95	12.6K	352.2K	165.62K
Nov 01, 2021	BETZ STEPHEN F.	SALE	24.79	5.67K	140.51K	178.22K
Nov 01, 2021	FUST MATTHEW K	SALE	25.50	8.95K	228.33K	12.54K
Oct 27, 2021	BETZ STEPHEN F.	SALE	24.00	3K	71.99K	183.88K
Oct 25, 2021	PERCEPTIVE ADVISORS LLC	PURCHASE	19.80	1.2M	23.76M	5.16M
Oct 21, 2021	BETZ STEPHEN F.	SALE	21.10	1.04K	21.98K	186.88K
Sep 08, 2021	FUST MATTHEW K	SALE	25.50	6.05K	154.17K	12.54K
Sep 07, 2021	STRUTHERS RICHARD SCOTT	SALE	25.00	10K	250K	90K
Jul 26, 2021	FUST MATTHEW K	SALE	19.59	5K	97.95K	12.54K
Jul 19, 2021	FUST MATTHEW K	SALE	19.50	5K	97.5K	12.54K
Jul 12, 2021	FUST MATTHEW K	SALE	20.71	5K	103.55K	12.54K
Apr 08, 2021	PERCEPTIVE ADVISORS LLC	PURCHASE	16.44	304.14K	5M	3.96M
Dec 03, 2020	STRUTHERS RICHARD SCOTT	PURCHASE	13.10	4K	52.4K	4K
Dec 02, 2020	STRUTHERS RICHARD SCOTT	PURCHASE	12.60	1K	12.6K	1K
Jul 16, 2020	STRUTHERS RICHARD SCOTT	SALE	14.46	17.5K	253.11K	890.81K
Jul 15, 2020	STRUTHERS RICHARD SCOTT	SALE	15.30	17.5K	267.72K	908.31K
Apr 17, 2020	VIVO CAPITAL VIII, LLC	SALE	15.40	74.33K	1.14M	2.16M
Apr 17, 2020	PERCEPTIVE ADVISORS LLC	PURCHASE	14.00	1.07M	15M	3.66M
Apr 16, 2020	VIVO CAPITAL VIII, LLC	SALE	15.20	26.53K	403.21K	2.24M
Apr 15, 2020	VIVO CAPITAL VIII, LLC	SALE	15.50	189.63K	2.94M	2.26M
Apr 07, 2020	VIVO CAPITAL VIII, LLC	SALE	14.20	5.37K	76.3K	2.45M
Apr 03, 2020	VIVO CAPITAL VIII, LLC	SALE	13.80	263.6K	3.64M	2.46M
Mar 09, 2020	VIVO CAPITAL VIII, LLC	SALE	19.50	347	6.77K	2.72M
Feb 10, 2020	VIVO CAPITAL VIII, LLC	SALE	21.40	1.45K	31.05K	2.72M
Feb 07, 2020	VIVO CAPITAL VIII, LLC	SALE	22.00	1.13K	24.95K	2.72M
Feb 04, 2020	VIVO CAPITAL VIII, LLC	SALE	22.80	2.58K	58.92K	2.72M
Jan 31, 2020	VIVO CAPITAL VIII, LLC	SALE	21.70	1.04K	22.5K	2.73M
Jan 30, 2020	VIVO CAPITAL VIII, LLC	SALE	22.10	1.46K	32.24K	2.73M
Jan 29, 2020	VIVO CAPITAL VIII, LLC	SALE	22.20	2.67K	59.34K	2.73M
Dec 16, 2019	FUST MATTHEW K	SALE	22.50	3.5K	78.75K	12.54K
Jun 21, 2019	5AM VENTURES IV, L.P.	SALE	22.20	240K	5.33M	2.27M

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES71.59K8

NET SHARES-71.59K8

SHARES HELD557.02K8

% NET SHARES-112.85%0%

Frequently Asked Questions