How many institutions own AXSM stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own AXSM shares is 483, representing 76.64% of the company's common stock.

Who are the major shareholders selling Axsome Therapeutics, Inc. stock?

PFM HEALTH SCIENCES, LP, in the last quarter, reduced its stake in AXSM by -52.57% restricting it's holding to 251.56 thousand shares of worth nearly $45.95M. MAN GROUP PLC also lessened -20.59% of the AXSM shares from its portfolio, reducing its holding to 228.64 thousand shares of worth $41.76M. EVENTIDE ASSET MANAGEMENT, LLC also shunned AXSM shares holding by -23.47% last quarter which brought its holding to 571.23 thousand shares worth $104.20M.

Investors who are buying AXSM stock?

As per its latest 13F filing, BANK OF AMERICA CORP /DE/ increased its stake in AXSM by 71.08% in the last quarter. The institutional holder raised its holding to 618.03 thousand shares having worth more than $112.88M. NORGES BANK also added 100% more shares of AXSM to its portfolio, raising its holding to 495.46 thousand shares of worth $90.49M. MORGAN STANLEY also increased its AXSM shares holding by 19.93% which brought its holding to 491.2 thousand shares worth $89.71M.

AXSM's major insiders: who are they?

The insider with the most stakes in AXSM is JEFFS ROGER , director at the company. Additionally, AXSM stock is highly held by director Coleman Mark and Chief Financial Officer Pizzie Nick among others.

Did an insider recently sell AXSM stock?

Company executives, directors, and other insiders own 15.7% percent of Axsome Therapeutics, Inc.'s stock. Within the last six months, there have been 23 transaction(s) in which AXSM insiders have sold stock, totaling 685.22K shares. Insiders that have sold shares include JACOBSON MARK L., COLEMAN MARK, and TABUTEAU HERRIOT.

Which insider recently purchased AXSM stock?

There have been 0 transaction(s) during the past 6-months in which Axsome Therapeutics, Inc. insiders have bought stock, totalling 0 shares

How much of AXSM does insiders own?

Around 215.39K Axsome Therapeutics, Inc. shares are held by insiders, which represents about 15.7% of AXSM stock.

Who is the insider with the largest stake?

AXSM director, JEFFS ROGER holds the largest portfolio of the company's shares. AXSM shares owned by JEFFS total nearly 57.51 thousand.

Which institution holds the most shares in AXSM?

PFM HEALTH SCIENCES, LP is the largest institutional owner in AXSM which holds 251.56 thousand shares worth $45.95M or 0.5% of the total AXSM shares outstanding followed by MAN GROUP PLC with ownership of 228.64 thousand shares representing 0.46% of the AXSM ownership. BANK OF AMERICA CORP /DE/ is the third largest stakeholder with 618.03 thousand shares or 1.24% of the ownership worth more than $112.88M.

Is Axsome Therapeutics, Inc. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the AXSM is concerned, it is a stock which is optionable.

Is there a short position on AXSM's shares?

Number of AXSM shares short is 2.71M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding AXSM shares are there?

As of today, 51.15M shares of AXSM are outstanding.

Is there many float in AXSM stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, AXSM has 43.24M shares in float.

AXSM short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for AXSM is 4.49.

Axsome Therapeutics (AXSM) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares5.33

Short Percent Of Float6.34

Shares Outstanding51.15M

Shares Float43.24M

Shares Short2.71M

Short Ratio4.49

6.34%

Short % of Float

5.33%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

15.7% Percentage of Shares held by All Insiders

76.64% Percentage of Shares held by All Institutions

90.91% Percentage of Float held by Institutions

483

Number of Institutions Holding Shares

Institutional Ownership

About 76.64% of AXSM shares are held by financial institutions. PFM HEALTH SCIENCES, LP is the top corporate investor, holding 251.56K shares valued at $45.95M. A 0.5% stake in Axsome Therapeutics, Inc. is owned by the company. MAN GROUP PLC owns 228.64K shares valued at $41.76M, which translates its holding of 0.46% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Dec 31, 2025	PFM HEALTH SCIENCES, LP	0.5%	251.56K	45.95M	-278.77K	-52.57%
Dec 31, 2025	MAN GROUP PLC	0.46%	228.64K	41.76M	-59.27K	-20.59%
Dec 31, 2025	BANK OF AMERICA CORP /DE/	1.24%	618.03K	112.88M	256.77K	+71.08%
Dec 31, 2025	EVENTIDE ASSET MANAGEMENT, LLC	1.14%	571.23K	104.2M	-175.17K	-23.47%
Dec 31, 2025	NORGES BANK	0.99%	495.46K	90.49M	495.46K	+100.00%
Dec 31, 2025	MORGAN STANLEY	0.98%	491.2K	89.71M	81.62K	+19.93%
Dec 31, 2025	ASSENAGON ASSET MANAGEMENT S.A.	0.94%	467.98K	85.47M	173.21K	+58.76%
Dec 31, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.87%	436.06K	79.64M	73.93K	+20.41%
Dec 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.81%	402.7K	73.55M	20.65K	+5.41%
Dec 31, 2025	UBS GROUP AG	0.71%	355.32K	64.9M	142.87K	+67.25%
Dec 31, 2025	NUVEEN, LLC	0.7%	349.21K	63.78M	50.87K	+17.05%
Dec 31, 2025	CITADEL ADVISORS LLC	0.35%	176K	32.14M	85.3K	+94.05%
Dec 31, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.35%	173.3K	31.65M	59.25K	+51.95%
Dec 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0.34%	170K	31.05M	20K	+13.33%
Dec 31, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.33%	164.87K	30.11M	-32.45K	-16.44%
Dec 31, 2025	SQUAREPOINT OPS LLC	0.31%	155K	28.31M	0	0
Dec 31, 2025	RAYMOND JAMES FINANCIAL INC	0.3%	150.1K	24.78M	-8.59K	-5.41%
Dec 31, 2025	TWO SIGMA INVESTMENTS, LP	0.29%	145.6K	26.59M	137.39K	+1,674.06%
Dec 31, 2025	JANE STREET GROUP, LLC	0.24%	117.6K	21.48B	29.7K	+33.79%
Dec 31, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.27%	133.88K	23.66M	1.17K	+0.88%
Dec 31, 2025	US BANCORP \DE\	0.26%	130.99K	23.92M	-548	-0.42%
Dec 31, 2025	RHENMAN & PARTNERS ASSET MANAGEMENT AB	0.23%	114.8K	20.97M	-58K	-33.56%
Dec 31, 2025	WCM INVESTMENT MANAGEMENT, LLC	0.22%	112.06K	16.67M	-7.64K	-6.38%
Dec 31, 2025	EMERALD ADVISERS, LLC	0.22%	108.08K	19.74M	-860	-0.79%
Dec 31, 2025	AQR CAPITAL MANAGEMENT LLC	0.21%	103.42K	18.89M	-15.24K	-12.84%
Dec 31, 2025	DNB ASSET MANAGEMENT AS	0.2%	101.1K	18.47M	-879	-0.86%
Dec 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.56%	279.4K	51.03M	6.2K	+2.27%
Dec 31, 2025	ORBIMED ADVISORS LLC	0.51%	253.12K	46.23M	-278.68K	-52.40%
Dec 31, 2025	JPMORGAN CHASE & CO	0.47%	233.19K	42.59M	-17.32K	-6.91%
Dec 31, 2025	TWO SIGMA ADVISERS, LP	0.38%	188.5K	34.43M	188.5K	+100.00%
Dec 31, 2025	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.38%	188.26K	34.38M	-20.81K	-9.95%
Dec 31, 2025	FRANKLIN RESOURCES INC	0.68%	342.57K	62.57M	56.98K	+19.95%
Dec 31, 2025	MARSHALL WACE, LLP	0.64%	320.57K	58.55M	-57.46K	-15.20%
Dec 31, 2025	D. E. SHAW & CO., INC.	1.1%	549.11K	100.29M	252.83K	+85.33%
Dec 31, 2025	RTW INVESTMENTS, LP	1.78%	888K	162.18M	-230.88K	-20.64%
Dec 31, 2025	FMR LLC	2.36%	1.18M	215.81M	253.74K	+27.35%
Dec 31, 2025	LOOMIS SAYLES & CO L P	0.63%	315.39K	57.6M	-14.73K	-4.46%
Dec 31, 2025	MACQUARIE MANAGEMENT HOLDINGS, INC.	1.98%	989.45K	180.71B	989.45K	+100.00%
Dec 31, 2025	PRINCIPAL FINANCIAL GROUP INC	0.73%	363.11K	66.32M	-5.32K	-1.44%
Dec 31, 2025	BANK OF NEW YORK MELLON CORP	0.51%	255.1K	46.59M	1.83K	+0.72%
Dec 31, 2025	DEUTSCHE BANK AG\	0.2%	98.26K	17.95M	1.57K	+1.62%
Dec 31, 2025	NICHOLAS INVESTMENT PARTNERS, LP	0.18%	91.56K	16.72M	42.91K	+88.18%
Dec 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	2.44%	1.22M	223.12M	-112.9K	-8.46%
Dec 31, 2025	INVESCO LTD.	2.55%	1.27M	232.59M	282.94K	+28.56%
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.02%	1.01M	184.54M	12.55K	+1.26%
Dec 31, 2025	DEEP TRACK CAPITAL, LP	2.3%	1.15M	210.04M	250K	+27.78%
Dec 31, 2025	STATE STREET CORP	1.92%	958.15K	175M	15.19K	+1.61%
Dec 31, 2025	BLACKROCK, INC.	7.82%	3.91M	714.77M	122.61K	+3.23%
Dec 31, 2025	TRI LOCUM PARTNERS LP	0.4%	201.63K	36.83M	-90.51K	-30.98%
Dec 31, 2025	CITIGROUP INC	0.41%	204.1K	37.28M	62.09K	+43.72%
Dec 31, 2025	FIRST TURN MANAGEMENT, LLC	0.41%	206.92K	37.79M	54.31K	+35.58%
Dec 31, 2025	VESTAL POINT CAPITAL, LP	0.42%	210K	38.35M	60K	+40.00%
Dec 31, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	0.44%	220.52K	40.28M	-2.89K	-1.29%
Dec 31, 2025	HOOD RIVER CAPITAL MANAGEMENT LLC	0.73%	366.18K	66.88M	6.22K	+1.73%
Dec 31, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.73%	367.58K	67.13M	-77.42K	-17.40%
Dec 31, 2025	NORTHERN TRUST CORP	0.78%	390.43K	71.31M	-19.1K	-4.66%
Dec 31, 2025	ROCKEFELLER CAPITAL MANAGEMENT L.P.	0.84%	418.14K	1.36M	412.4K	+7,188.50%
Dec 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	3.02%	1.51M	275.76M	472.42K	+45.54%
Dec 31, 2025	VANGUARD GROUP INC	8.33%	4.16M	760.66M	-15.83K	-0.38%
Dec 31, 2025	GRANITE INVESTMENT PARTNERS, LLC	0.17%	84.89K	15.51M	-3.66K	-4.14%
Dec 31, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.17%	87.25K	15.94M	558	+0.64%
Dec 31, 2025	FEDERATED HERMES, INC.	0.17%	87.28K	15.94M	30K	+52.36%
Dec 31, 2025	WELLS FARGO & COMPANY/MN	0.18%	89.66K	16.38M	34.39K	+62.21%
Dec 31, 2025	M&G PLC	0.18%	90.33K	16.53M	90.33K	+100.00%
Dec 31, 2025	ROYCE & ASSOCIATES LP	0.19%	94.02K	17.17M	37.98K	+67.78%
Dec 31, 2025	ABRDN PLC	0.19%	97.41K	17.79M	2.77K	+2.92%
Dec 31, 2025	GOLDMAN SACHS GROUP INC	0.6%	300.91K	54.96M	76.77K	+34.25%
Dec 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.61%	304.39K	55.59M	114.28K	+60.11%
Dec 31, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.65%	325.44K	59.44M	-186	-0.06%
Dec 31, 2025	ALETHEA CAPITAL MANAGEMENT, LLC	1.34%	668.71K	122.13M	-2.17K	-0.32%
Dec 31, 2025	NATIONALE-NEDERLANDEN POWSZECHNE TOWARZYSTWO EMERYTALNE S.A.	0.56%	278.84K	50.93M	-47.48K	-14.55%
Dec 31, 2025	SUMMIT FINANCIAL, LLC	0.14%	70.63K	12.9M	-6.91K	-8.91%
Dec 31, 2025	IRIDIAN ASSET MANAGEMENT LLC/CT	0.15%	73.78K	13.48M	-9.77K	-11.69%
Dec 31, 2025	BARCLAYS PLC	0.15%	76.85K	14.04M	4.79K	+6.64%
Sep 30, 2025	EMERALD ADVISERS, LLC	0.22%	108.94K	13.23M	-3.53K	-3.14%
Sep 30, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.23%	114.05K	13.85M	-25.24K	-18.12%
Sep 30, 2025	WCM INVESTMENT MANAGEMENT, LLC	0.24%	119.7K	14.08M	30	+0.03%
Sep 30, 2025	US BANCORP \DE\	0.27%	131.53K	15.97M	686	+0.52%
Sep 30, 2025	TRI LOCUM PARTNERS LP	0.59%	292.14K	35.48M	134.28K	+85.06%
Sep 30, 2025	CITIGROUP INC	0.29%	142.01K	17.25M	57K	+67.05%
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.3%	150K	18.22M	11.3K	+8.15%
Sep 30, 2025	BLACKROCK, INC.	7.67%	3.79M	460.41M	-44.06K	-1.15%
Sep 30, 2025	NUVEEN, LLC	0.6%	298.34K	36.23M	15.37K	+5.43%
Sep 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	2.7%	1.33M	162.08M	609.52K	+84.07%
Sep 30, 2025	VANGUARD GROUP INC	8.46%	4.18M	507.74M	235.63K	+5.97%
Sep 30, 2025	VESTAL POINT CAPITAL, LP	0.3%	150K	18.22M	150K	+100.00%
Sep 30, 2025	FIRST TURN MANAGEMENT, LLC	0.31%	152.61K	18.53M	8.21K	+5.69%
Sep 30, 2025	SQUAREPOINT OPS LLC	0.31%	155K	18.82M	-8K	-4.91%
Sep 30, 2025	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.42%	209.07K	25.39M	-15.65K	-6.97%
Sep 30, 2025	UBS GROUP AG	0.43%	212.45K	25.8M	-383K	-64.32%
Sep 30, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	0.45%	223.41K	27.13M	128	+0.06%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	0.45%	224.14K	27.22M	-4.07K	-1.78%
Sep 30, 2025	JPMORGAN CHASE & CO	0.51%	250.51K	30.42M	62.79K	+33.44%
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.51%	253.26K	30.76M	49.63K	+24.37%
Sep 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.55%	273.2K	33.18M	94.9K	+53.22%
Sep 30, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	0.55%	274.01K	33.28M	25.29K	+10.17%
Sep 30, 2025	HOOD RIVER CAPITAL MANAGEMENT LLC	0.73%	359.96K	43.72M	-11.15K	-3.00%
Sep 30, 2025	DEEP TRACK CAPITAL, LP	1.82%	900K	109.31M	98.63K	+12.31%
Sep 30, 2025	FMR LLC	1.88%	927.88K	112.69M	-48.85K	-5.00%
Sep 30, 2025	STATE STREET CORP	1.91%	942.96K	114.52M	-15.54K	-1.62%
Sep 30, 2025	LOOMIS SAYLES & CO L P	0.67%	330.13K	40.09M	52.66K	+18.98%
Sep 30, 2025	WOODLINE PARTNERS LP	0.67%	331.86K	40.3M	733	+0.22%
Sep 30, 2025	RHENMAN & PARTNERS ASSET MANAGEMENT AB	0.35%	172.8K	20.99M	82K	+90.31%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.38%	190.11K	23.09M	3.67K	+1.97%
Sep 30, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.4%	197.32K	23.96M	13.15K	+7.14%
Sep 30, 2025	B. RILEY WEALTH ADVISORS, INC.	0.4%	200K	242.9K	200K	+100.00%
Sep 30, 2025	FRANKLIN RESOURCES INC	0.58%	285.6K	34.69M	7.09K	+2.55%
Sep 30, 2025	MAN GROUP PLC	0.58%	287.91K	34.97M	-237.16K	-45.17%
Sep 30, 2025	ASSENAGON ASSET MANAGEMENT S.A.	0.6%	294.77K	35.8M	113.81K	+62.89%
Sep 30, 2025	D. E. SHAW & CO., INC.	0.6%	296.29K	35.98M	95.52K	+47.58%
Sep 30, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.66%	325.63K	39.55M	-65.99K	-16.85%
Sep 30, 2025	NATIONALE-NEDERLANDEN POWSZECHNE TOWARZYSTWO EMERYTALNE S.A.	0.66%	326.32K	39.63M	0	0
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.73%	361.26K	43.88M	-392.17K	-52.05%
Sep 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.73%	362.14K	43.98M	-49.71K	-12.07%
Sep 30, 2025	PRINCIPAL FINANCIAL GROUP INC	0.75%	368.43K	44.75M	12.92K	+3.64%
Sep 30, 2025	MARSHALL WACE, LLP	0.76%	378.02K	45.91M	321.31K	+566.52%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.77%	382.05K	46.4M	25.4K	+7.12%
Sep 30, 2025	SOFINNOVA INVESTMENTS, INC.	0.8%	393.5K	47.79M	299.89K	+320.36%
Sep 30, 2025	NORTHERN TRUST CORP	0.83%	409.54K	49.74M	141	+0.03%
Sep 30, 2025	MORGAN STANLEY	0.83%	409.58K	49.74M	-38.34K	-8.56%
Sep 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.9%	445K	54.05M	-2K	-0.45%
Sep 30, 2025	BVF INC/IL	0.98%	486.76K	59.12M	-1.2M	-71.20%
Sep 30, 2025	PFM HEALTH SCIENCES, LP	1.07%	530.33K	64.41M	47.23K	+9.78%
Sep 30, 2025	ORBIMED ADVISORS LLC	1.08%	531.8K	64.59M	103.9K	+24.28%
Sep 30, 2025	ALETHEA CAPITAL MANAGEMENT, LLC	1.36%	670.88K	81.48M	3.52K	+0.53%
Sep 30, 2025	EVENTIDE ASSET MANAGEMENT, LLC	1.51%	746.4K	90.64M	20.73K	+2.86%
Sep 30, 2025	FAIRMOUNT FUNDS MANAGEMENT LLC	1.65%	815.18K	99M	0	0
Sep 30, 2025	INVESCO LTD.	2%	990.56K	120.3M	419.01K	+73.31%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.02%	997.7K	121.19M	8.25K	+0.83%
Sep 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	2.1%	1.04M	126M	424.71K	+69.31%
Sep 30, 2025	MACQUARIE GROUP LTD	2.19%	1.08M	131.72M	-53.21K	-4.68%
Sep 30, 2025	RTW INVESTMENTS, LP	2.26%	1.12M	135.89M	-398.02K	-26.24%
Sep 30, 2025	RAYMOND JAMES FINANCIAL INC	0.32%	158.69K	19.27M	-2.72K	-1.69%
Sep 30, 2025	BLAIR WILLIAM & CO/IL	0.1%	50.08K	6.08M	595	+1.20%
Sep 30, 2025	MOODY ALDRICH PARTNERS LLC	0.1%	51.48K	6.25M	-9.93K	-16.18%
Sep 30, 2025	PRIVIUM FUND MANAGEMENT B.V.	0.11%	52.73K	6.4M	0	0
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0.11%	55.27K	6.71M	-430	-0.77%
Sep 30, 2025	ROYCE & ASSOCIATES LP	0.11%	56.04K	6.81M	30.28K	+117.56%
Sep 30, 2025	HIGHTOWER ADVISORS, LLC	0.12%	57.12K	6.94M	46.15K	+421.03%
Sep 30, 2025	FEDERATED HERMES, INC.	0.12%	57.29K	6.96M	816	+1.45%
Sep 30, 2025	CLEARBRIDGE INVESTMENTS, LLC	0.12%	57.67K	7M	1.35K	+2.40%
Sep 30, 2025	RHUMBLINE ADVISERS	0.12%	60.78K	7.38M	-1.03K	-1.66%
Sep 30, 2025	CANADA PENSION PLAN INVESTMENT BOARD	0.13%	64.4K	7.82M	-7.9K	-10.93%
Sep 30, 2025	PEREGRINE CAPITAL MANAGEMENT LLC	0.13%	64.52K	7.84M	-8.95K	-12.18%
Sep 30, 2025	EMERALD MUTUAL FUND ADVISERS TRUST	0.13%	65.51K	7.96M	1.57K	+2.46%
Sep 30, 2025	SWISS NATIONAL BANK	0.14%	66.8K	8.11M	1.6K	+2.45%
Sep 30, 2025	UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH	0.14%	67.9K	8.25M	15.93K	+30.66%
Sep 30, 2025	BARCLAYS PLC	0.15%	72.07K	8.75M	-25.42K	-26.08%
Sep 30, 2025	IRIDIAN ASSET MANAGEMENT LLC/CT	0.17%	83.55K	10.15M	-8.21K	-8.95%
Sep 30, 2025	GRANITE INVESTMENT PARTNERS, LLC	0.18%	88.56K	10.76M	-39.97K	-31.10%
Sep 30, 2025	NEUBERGER BERMAN GROUP LLC	0.18%	91.18K	11.07M	20.55K	+29.09%
Sep 30, 2025	ABRDN PLC	0.19%	94.65K	11.5M	12.73K	+15.54%
Sep 30, 2025	DEUTSCHE BANK AG\	0.2%	96.69K	11.74M	3.8K	+4.09%
Sep 30, 2025	HSBC HOLDINGS PLC	0.2%	101K	12.27M	2.88K	+2.94%
Sep 30, 2025	DNB ASSET MANAGEMENT AS	0.21%	101.98K	12.39M	25.34K	+33.06%
Jun 30, 2025	MACQUARIE GROUP LTD	2.3%	1.14M	118.77M	161.49K	+16.54%
Jun 30, 2025	SQUAREPOINT OPS LLC	0.33%	163K	17.02M	21.4K	+15.12%
Jun 30, 2025	CUBIST SYSTEMATIC STRATEGIES, LLC	0.32%	159.23K	16.62M	-18.58K	-10.45%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.72%	356.65K	37.23M	19.41K	+5.75%
Jun 30, 2025	FIRST TURN MANAGEMENT, LLC	0.29%	144.4K	15.07M	26.22K	+22.19%
Jun 30, 2025	TRI LOCUM PARTNERS LP	0.32%	157.86K	16.48M	56.62K	+55.93%
Jun 30, 2025	RAYMOND JAMES FINANCIAL INC	0.33%	161.41K	16.85M	6.34K	+4.09%
Jun 30, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.37%	184.16K	19.22M	5.21K	+2.91%
Jun 30, 2025	JPMORGAN CHASE & CO	0.38%	187.73K	19.6M	62.95K	+50.44%
Jun 30, 2025	BANK OF NEW YORK MELLON CORP	0.41%	203.63K	21.26M	72.61K	+55.42%
Jun 30, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	0.45%	223.28K	23.31M	9.14K	+4.27%
Jun 30, 2025	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.45%	224.72K	23.46M	48.78K	+27.72%
Jun 30, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	0.5%	248.73K	25.97M	-18.27K	-6.84%
Jun 30, 2025		0.57%	282.97K	29.54M	-130.17K	-31.51%
Jun 30, 2025	WOODLINE PARTNERS LP	0.67%	331.13K	34.57M	27.05K	+8.89%
Jun 30, 2025	PRINCIPAL FINANCIAL GROUP INC	0.72%	355.51K	37.11M	59.84K	+20.24%
Jun 30, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.79%	391.62K	40.88M	109.24K	+38.69%
Jun 30, 2025	PFM HEALTH SCIENCES, LP	0.98%	483.11K	50.43M	-73.44K	-13.20%
Jun 30, 2025	MAN GROUP PLC	1.06%	525.07K	54.81M	11.85K	+2.31%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.36%	178.3K	18.61M	-126K	-41.41%
Jun 30, 2025	NUVEEN, LLC	0.57%	282.97K	29.54M	-130.17K	-31.51%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	1.52%	753.43K	78.65M	219.53K	+41.12%
Jun 30, 2025	DEEP TRACK CAPITAL, LP	1.62%	801.37K	83.66M	801.37K	+100.00%
Jun 30, 2025	FAIRMOUNT FUNDS MANAGEMENT LLC	1.65%	815.18K	85.1M	0	0
Jun 30, 2025	FMR LLC	1.98%	976.73K	101.96M	-270.5K	-21.69%
Jun 30, 2025	RTW INVESTMENTS, LP	3.07%	1.52M	158.35M	-1.41M	-48.10%
Jun 30, 2025	BVF INC/IL	3.42%	1.69M	176.44M	0	0
Jun 30, 2025	BLACKROCK, INC.	7.76%	3.83M	400.33M	310.58K	+8.81%
Jun 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	1.47%	725.04K	75.69M	21.77K	+3.09%
Jun 30, 2025	CANADA PENSION PLAN INVESTMENT BOARD	0.15%	72.3K	7.55M	27.8K	+62.47%
Jun 30, 2025	PEREGRINE CAPITAL MANAGEMENT LLC	0.15%	73.47K	7.67M	13.75K	+23.02%
Jun 30, 2025	DNB ASSET MANAGEMENT AS	0.16%	76.64K	8M	15.11K	+24.56%
Jun 30, 2025	CANDRIAM S.C.A.	0.16%	76.73K	8.01M	-3.2K	-4.01%
Jun 30, 2025	ABRDN PLC	0.17%	81.92K	8.55M	17.96K	+28.09%
Jun 30, 2025	SPEARS ABACUS ADVISORS LLC	0.17%	84.15K	8.78M	-113	-0.13%
Jun 30, 2025	RHENMAN & PARTNERS ASSET MANAGEMENT AB	0.18%	90.8K	9.48M	-18.8K	-17.15%
Jun 30, 2025	IRIDIAN ASSET MANAGEMENT LLC/CT	0.19%	91.76K	9.58M	-14.55K	-13.69%
Jun 30, 2025	SOFINNOVA INVESTMENTS, INC.	0.19%	93.61K	9.77M	-81.71K	-46.61%
Jun 30, 2025	AVIDITY PARTNERS MANAGEMENT LP	0.19%	94.5K	9.86M	17.5K	+22.73%
Jun 30, 2025	READYSTATE ASSET MANAGEMENT LP	0.19%	94.57K	9.87M	35.02K	+58.80%
Jun 30, 2025	CORMORANT ASSET MANAGEMENT, LP	0.2%	100K	10.44M	-150K	-60.00%
Jun 30, 2025	BRIDGEWATER ASSOCIATES, LP	0.22%	107.29K	11.2M	64.47K	+150.54%
Jun 30, 2025	EMERALD ADVISERS, LLC	0.23%	112.47K	11.74M	112.47K	+100.00%
Jun 30, 2025	WCM INVESTMENT MANAGEMENT, LLC	0.24%	119.67K	12.37M	7.72K	+6.89%
Jun 30, 2025	AQR CAPITAL MANAGEMENT LLC	0.26%	127.82K	13.34B	69.45K	+119.00%
Jun 30, 2025	VANGUARD GROUP INC	7.98%	3.95M	411.82M	68.08K	+1.76%
Jun 30, 2025	STATE STREET CORP	1.94%	958.5K	100.06M	52.48K	+5.79%
Jun 30, 2025	EVENTIDE ASSET MANAGEMENT, LLC	1.47%	725.67K	75.75M	-19.18K	-2.57%
Jun 30, 2025	UBS GROUP AG	1.2%	595.46K	62.16M	306.81K	+106.29%
Jun 30, 2025	INVESCO LTD.	1.16%	571.55K	59.66M	-285.45K	-33.31%
Jun 30, 2025	NORGES BANK	0.95%	468.33K	48.89M	468.33K	+100.00%
Jun 30, 2025	MORGAN STANLEY	0.91%	447.92K	46.76B	-9.5K	-2.08%
Jun 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.83%	411.85K	42.99M	78.65K	+23.60%
Jun 30, 2025	HOOD RIVER CAPITAL MANAGEMENT LLC	0.75%	371.1K	38.74M	371.1K	+100.00%
Jun 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.71%	350.97K	36.64M	224.78K	+178.12%
Jun 30, 2025	NATIONALE-NEDERLANDEN POWSZECHNE TOWARZYSTWO EMERYTALNE S.A.	0.66%	326.32K	34.06M	40.82K	+14.30%
Jun 30, 2025	FRANKLIN RESOURCES INC	0.56%	278.51K	29.07M	52K	+22.95%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.46%	228.2K	23.82B	-73.51K	-24.37%
Jun 30, 2025	PERCEPTIVE ADVISORS LLC	0.4%	198.53K	20.72M	-156.57K	-44.09%
Jun 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.38%	186.44K	19.46M	3.81K	+2.08%
Jun 30, 2025	ASSENAGON ASSET MANAGEMENT S.A.	0.37%	180.96K	18.89M	-446.46K	-71.16%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	2%	989.45K	103.3M	54.6K	+5.84%
Jun 30, 2025	ALETHEA CAPITAL MANAGEMENT, LLC	1.35%	667.37K	69.67M	0	0
Jun 30, 2025	JUMP FINANCIAL, LLC	0.26%	128.5K	13.41M	35.86K	+38.71%
Jun 30, 2025	GRANITE INVESTMENT PARTNERS, LLC	0.26%	128.53K	13.42M	-10.19K	-7.35%
Jun 30, 2025	BLACKSTONE INC.	0.28%	140K	14.61M	140K	+100.00%
Jun 30, 2025	D. E. SHAW & CO., INC.	0.41%	200.76K	20.96B	-346.9K	-63.34%
Jun 30, 2025	LOOMIS SAYLES & CO L P	0.56%	277.47K	28.96M	-6.71K	-2.36%
Jun 30, 2025	EMERALD MUTUAL FUND ADVISERS TRUST	0.13%	63.94K	6.67M	63.94K	+100.00%
Jun 30, 2025	EDGESTREAM PARTNERS, L.P.	0.14%	69.96K	7.3M	-125	-0.18%
Jun 30, 2025	MOODY ALDRICH PARTNERS LLC	0.12%	61.41K	6.41M	-929	-1.49%
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.24%	612.74K	63.97M	580.77K	+1,816.20%
Jun 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.9%	447K	46.66M	399K	+831.25%
Jun 30, 2025	ORBIMED ADVISORS LLC	0.87%	427.9K	44.67M	41.2K	+10.65%
Jun 30, 2025	NORTHERN TRUST CORP	0.83%	409.39K	42.74M	-1.58K	-0.38%
Mar 31, 2025	ORBIMED ADVISORS LLC	0.79%	386.7K	45.1M	386.7K	+100.00%
Mar 31, 2025	BVF INC/IL	3.46%	1.69M	197.13M	302.16K	+21.77%
Mar 31, 2025	VANGUARD GROUP INC	7.93%	3.88M	452.17M	-25.54K	-0.65%
Mar 31, 2025	BLACKROCK, INC.	7.21%	3.52M	411.05M	-8.98K	-0.25%
Mar 31, 2025	RTW INVESTMENTS, LP	5.98%	2.92M	340.88M	-1.13M	-27.86%
Mar 31, 2025	FMR LLC	2.55%	1.25M	145.46M	246.79K	+24.67%
Mar 31, 2025	MACQUARIE GROUP LTD	2%	976.26K	113.86M	12.21K	+1.27%
Mar 31, 2025	FAIRMOUNT FUNDS MANAGEMENT LLC	1.67%	815.18K	95.07M	-653.81K	-44.51%
Mar 31, 2025	EVENTIDE ASSET MANAGEMENT, LLC	1.52%	744.85K	86.88M	-83.86K	-10.12%
Mar 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	1.44%	703.28K	82.02M	30.12K	+4.47%
Mar 31, 2025	ALETHEA CAPITAL MANAGEMENT, LLC	1.37%	667.37K	77.84M	-66.95K	-9.12%
Mar 31, 2025	ASSENAGON ASSET MANAGEMENT S.A.	1.28%	627.42K	73.18M	623.72K	+16,852.66%
Mar 31, 2025		0.85%	413.14K	48.18M	413.14K	+100.00%
Mar 31, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.37%	178.96K	20.87M	156.68K	+703.32%
Mar 31, 2025	CUBIST SYSTEMATIC STRATEGIES, LLC	0.36%	177.81K	20.74M	60.88K	+52.06%
Mar 31, 2025	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.36%	175.94K	20.52M	102.45K	+139.39%
Mar 31, 2025	SOFINNOVA INVESTMENTS, INC.	0.36%	175.32K	20.45M	-316.41K	-64.35%
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	0.48%	235.31K	27.44M	231.07K	+5,441.95%
Mar 31, 2025	D. E. SHAW & CO., INC.	1.12%	547.67K	63.87M	527.32K	+2,591.76%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	1.09%	533.9K	62.27M	329.32K	+160.97%
Mar 31, 2025	MAN GROUP PLC	1.05%	513.22K	59.86M	349.83K	+214.11%
Mar 31, 2025	MORGAN STANLEY	0.94%	457.42K	53.35M	-119.44K	-20.71%
Mar 31, 2025	NORTHERN TRUST CORP	0.84%	410.97K	47.93M	8.47K	+2.10%
Mar 31, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.68%	333.21K	38.86M	328.53K	+7,022.81%
Mar 31, 2025	CORMORANT ASSET MANAGEMENT, LP	0.51%	250K	29.16M	-75K	-23.08%
Mar 31, 2025	FRANKLIN RESOURCES INC	0.46%	226.52K	26.42M	44.23K	+24.26%
Mar 31, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	0.44%	214.14K	24.98M	214.14K	+100.00%
Mar 31, 2025	PFM HEALTH SCIENCES, LP	1.14%	556.55K	64.91M	89.12K	+19.07%
Mar 31, 2025	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.48%	235.38K	27.45M	235.38K	+100.00%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.69%	337.25K	39.33M	9.21K	+2.81%
Mar 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.37%	182.63K	21.3M	-3.03K	-1.63%
Mar 31, 2025	RAYMOND JAMES FINANCIAL INC	0.32%	155.08K	18.09M	-19.51K	-11.18%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.91%	934.85K	109.06M	22.32K	+2.45%
Mar 31, 2025	STATE STREET CORP	1.85%	906.02K	105.67M	-41.23K	-4.35%
Mar 31, 2025	INVESCO LTD.	1.75%	857K	99.95M	164.54K	+23.76%
Mar 31, 2025	PERCEPTIVE ADVISORS LLC	0.73%	355.11K	41.42M	-308.97K	-46.53%
Mar 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.51%	248.6K	28.99M	-142.4K	-36.42%
Mar 31, 2025	WOODLINE PARTNERS LP	0.62%	304.08K	35.47M	-104.36K	-25.55%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.62%	301.72K	35.19M	84.15K	+38.68%
Mar 31, 2025	PRINCIPAL FINANCIAL GROUP INC	0.61%	295.67K	34.48M	88.61K	+42.79%
Mar 31, 2025	UBS GROUP AG	0.59%	288.65K	33.66M	141.3K	+95.90%
Mar 31, 2025	NATIONALE-NEDERLANDEN POWSZECHNE TOWARZYSTWO EMERYTALNE S.A.	0.58%	285.49K	33.3M	251.78K	+746.69%
Mar 31, 2025	LOOMIS SAYLES & CO L P	0.58%	284.17K	33.14M	-5.94K	-2.05%
Mar 31, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.58%	282.38K	32.93M	126.47K	+81.11%
Mar 31, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	0.55%	267K	31.14M	267K	+100.00%
Mar 31, 2025	TWO SIGMA ADVISERS, LP	0.31%	149.6K	17.45M	143.3K	+2,274.60%
Mar 31, 2025	SQUAREPOINT OPS LLC	0.29%	141.6K	16.51M	52.17K	+58.33%
Mar 31, 2025	GRANITE INVESTMENT PARTNERS, LLC	0.28%	138.72K	16.18M	47.07K	+51.36%
Mar 31, 2025	1832 ASSET MANAGEMENT L.P.	0.74%	363.2K	42.36M	363.2K	+100.00%
Mar 31, 2024	IRIDIAN ASSET MANAGEMENT LLC/CT	0.28%	128.84K	10.28M	-9.5K	-6.86%
Mar 31, 2024	CHECKPOINT CAPITAL L.P.	0.29%	132.44K	10.57M	-22.91K	-14.75%
Mar 31, 2024	US BANCORP \DE\	0.29%	133.51K	10.65M	-9.92K	-6.92%
Mar 31, 2024	ALTIUM CAPITAL MANAGEMENT LP	0.3%	138K	11.01M	0	0
Mar 31, 2024	HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND	0.3%	138.3K	11.04M	138.3K	+100.00%
Mar 31, 2024	AFFINITY ASSET ADVISORS, LLC	0.31%	139.76K	11.15M	89.76K	+179.52%
Mar 31, 2024	RHENMAN & PARTNERS ASSET MANAGEMENT AB	0.32%	143.6K	11.46M	64.5K	+81.54%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.41%	185.71K	14.82M	9.55K	+5.42%
Mar 31, 2024	JPMORGAN CHASE & CO	0.43%	195.26K	15.58M	5.36K	+2.82%
Mar 31, 2024	JANE STREET GROUP, LLC	0.44%	199.08K	15.89M	106.25K	+114.45%
Mar 31, 2024	DRIEHAUS CAPITAL MANAGEMENT LLC	0.45%	204.7K	16.33M	-61.14K	-23.00%
Mar 31, 2024	GHOST TREE CAPITAL, LLC	0.46%	210K	16.76M	45K	+27.27%
Mar 31, 2024	BARCLAYS PLC	0.48%	220.1K	17.56M	28.24K	+14.72%
Mar 31, 2024	EAGLE ASSET MANAGEMENT INC	0.5%	226.52K	17.44M	226.52K	+100.00%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.54%	245.53K	19.59M	10.88K	+4.64%
Mar 31, 2024	INVESCO LTD.	0.54%	245.65K	19.6M	199.49K	+432.14%
Mar 31, 2024	LOOMIS SAYLES & CO L P	0.62%	279.79K	22.33M	279.79K	+100.00%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.64%	291.61K	23.27M	85.8K	+41.69%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.66%	301.07K	24.03M	5.37K	+1.82%
Mar 31, 2024	JEFFERIES FINANCIAL GROUP INC.	0.73%	332.77K	26.55M	-230.57K	-40.93%
Mar 31, 2024	NORTHERN TRUST CORP	0.74%	336.09K	26.82M	-7.22K	-2.10%
Mar 31, 2024	FIRST TURN MANAGEMENT, LLC	0.75%	342.17K	27.31M	46.75K	+15.82%
Mar 31, 2024	PERCEPTIVE ADVISORS LLC	2.43%	1.11M	88.21M	67.32K	+6.49%
Mar 31, 2024	BLACKROCK INC.	7.03%	3.2M	255M	-44.26K	-1.37%
Mar 31, 2024	RTW INVESTMENTS, LP	9.89%	4.49M	358.52M	3.08K	+0.07%
Mar 31, 2024	EVENTIDE ASSET MANAGEMENT, LLC	0.76%	346.71K	27.67M	0	0
Mar 31, 2024	PICTET ASSET MANAGEMENT HOLDING SA	0.78%	352.37K	28.07M	-346.57K	-49.59%
Mar 31, 2024	WELLINGTON MANAGEMENT GROUP LLP	1.49%	676.65K	54M	436.83K	+182.15%
Mar 31, 2024	BELLEVUE GROUP AG	1.51%	685.48K	54.7M	50.1K	+7.89%
Mar 31, 2024	MACQUARIE GROUP LTD	1.54%	700.41K	55.89M	672.89K	+2,444.72%
Mar 31, 2024	ALETHEA CAPITAL MANAGEMENT, LLC	1.63%	740.79K	59.12M	-11.25K	-1.50%
Mar 31, 2024	MILLENNIUM MANAGEMENT LLC	1.63%	741.52K	59.17M	-168.45K	-18.51%
Mar 31, 2024	CITADEL ADVISORS LLC	2.52%	1.14M	91.26M	54.56K	+5.01%
Mar 31, 2024	DEEP TRACK CAPITAL, LP	2.87%	1.3M	104.12M	304.72K	+30.47%
Mar 31, 2024	FAIRMOUNT FUNDS MANAGEMENT LLC	5.2%	2.36M	188.33M	0	0
Mar 31, 2024	VANGUARD GROUP INC	8.23%	3.74M	298.47M	43.51K	+1.18%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.34%	153.77K	12.27M	-12.52K	-7.53%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.35%	157.8K	12.59M	-163.2K	-50.84%
Mar 31, 2024	WOODLINE PARTNERS LP	0.79%	360.13K	28.74M	-202.04K	-35.94%
Mar 31, 2024	POINT72 ASSET MANAGEMENT, L.P.	0.83%	378.86K	30.23M	-458.34K	-54.75%
Mar 31, 2024	BOXER CAPITAL, LLC	0.88%	400K	31.92M	0	0
Mar 31, 2024	AVIDITY PARTNERS MANAGEMENT LP	0.95%	431K	34.39M	-28.4K	-6.18%
Mar 31, 2024	PFM HEALTH SCIENCES, LP	1.03%	467.43K	37.3M	0	0
Mar 31, 2024	ADAGE CAPITAL PARTNERS GP, L.L.C.	1.13%	515K	41.1M	150K	+41.10%
Mar 31, 2024	HOOD RIVER CAPITAL MANAGEMENT LLC	1.15%	520.75K	41.56M	128K	+32.59%
Mar 31, 2024	FMR LLC	1.82%	828.55K	66.12M	-53.48K	-6.06%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	1.86%	845.41K	67.47M	23.1K	+2.81%
Mar 31, 2024	STATE STREET CORP	2.07%	938.72K	74.91M	14.53K	+1.57%
Mar 31, 2024	MORGAN STANLEY	2.08%	943.88K	75.32M	324.5K	+52.39%
Mar 31, 2024	RA CAPITAL MANAGEMENT, L.P.	2.2%	1M	79.8M	0	0
Mar 31, 2024	MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC	0.09%	41.62K	3.32M	7.04K	+20.37%
Mar 31, 2024	CREDIT SUISSE AG/	0.1%	43.72K	3.49M	-362	-0.82%
Mar 31, 2024	BALDWIN BROTHERS LLC/MA	0.11%	49.7K	3.97M	700	+1.43%
Mar 31, 2024	RHUMBLINE ADVISERS	0.12%	52.26K	4.17M	1.62K	+3.20%
Mar 31, 2024	SCHRODER INVESTMENT MANAGEMENT GROUP	0.13%	58.3K	4.65M	0	0
Mar 31, 2024	SWISS NATIONAL BANK	0.13%	60.5K	4.83M	0	0
Mar 31, 2024	UBS GROUP AG	0.14%	61.32K	4.89M	21.2K	+52.82%
Mar 31, 2024	BLAIR WILLIAM & CO/IL	0.14%	63.55K	5.07M	55.03K	+645.86%
Mar 31, 2024	FIRST TRUST ADVISORS LP	0.14%	65.51K	5.23M	-4.4K	-6.29%
Mar 31, 2024	MOODY ALDRICH PARTNERS LLC	0.14%	65.66K	5.24M	-1.21K	-1.81%
Mar 31, 2024	ATIKA CAPITAL MANAGEMENT LLC	0.15%	68K	5.43M	1.3K	+1.95%
Mar 31, 2024	HENNION & WALSH ASSET MANAGEMENT, INC.	0.15%	69.48K	5.54M	8.87K	+14.63%
Mar 31, 2024	SPIDERROCK ADVISORS, LLC	0.15%	70.02K	5.08M	70.02K	+100.00%
Mar 31, 2024	CANDRIAM S.C.A.	0.17%	75.08K	5.99M	-10K	-11.75%
Mar 31, 2024	ARTAL GROUP S.A.	0.17%	76.84K	6.13M	76.84K	+100.00%
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	0.18%	80.15K	6.4M	38.86K	+94.12%
Mar 31, 2024	PRIVIUM FUND MANAGEMENT B.V.	0.18%	82.03K	6.55M	10K	+13.88%
Mar 31, 2024	BNP PARIBAS ARBITRAGE, SNC	0.18%	82.54K	6.59M	63.07K	+323.80%
Mar 31, 2024	SPEARS ABACUS ADVISORS LLC	0.18%	82.73K	6.6M	82.73K	+100.00%
Mar 31, 2024	LINDBROOK CAPITAL, LLC	0.18%	83.77K	6.68M	-318	-0.38%
Mar 31, 2024	PEREGRINE CAPITAL MANAGEMENT LLC	0.19%	86.14K	6.87M	1.32K	+1.55%
Mar 31, 2024	CLEARBRIDGE INVESTMENTS, LLC	0.2%	89.37K	7.13M	89.37K	+100.00%
Mar 31, 2024	NEUBERGER BERMAN GROUP LLC	0.2%	91.66K	7.31M	47.34K	+106.83%
Mar 31, 2024	CITIGROUP INC	0.21%	95.07K	7.59M	-6.66K	-6.54%
Mar 31, 2024	FRANKLIN RESOURCES INC	0.24%	107.87K	8.61M	104.33K	+2,942.05%
Mar 31, 2024	WCM INVESTMENT MANAGEMENT, LLC	0.25%	111.59K	8.9M	6.78K	+6.47%
Dec 31, 2023	JEFFERIES FINANCIAL GROUP INC.	1.2%	563.34K	44.84M	10.14K	+1.83%
Dec 31, 2023	CITIGROUP INC	0.22%	101.73K	8.1M	-935	-0.91%
Dec 31, 2023	WCM INVESTMENT MANAGEMENT, LLC	0.22%	104.81K	8.34M	8.85K	+9.22%
Dec 31, 2023	SCHONFELD STRATEGIC ADVISORS LLC	0.23%	106.84K	8.5M	39.14K	+57.82%
Dec 31, 2023	TRI LOCUM PARTNERS LP	0.28%	130.74K	10.41M	-11.77K	-8.26%
Dec 31, 2023	ALTIUM CAPITAL MANAGEMENT LP	0.29%	138K	10.98M	46K	+50.00%
Dec 31, 2023	IRIDIAN ASSET MANAGEMENT LLC/CT	0.29%	138.34K	11.01M	-6.7K	-4.62%
Dec 31, 2023	US BANCORP \DE\	0.3%	143.42K	11.42M	4.65K	+3.35%
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	0.31%	146.56K	11.67M	123.95K	+548.25%
Dec 31, 2023	GHOST TREE CAPITAL, LLC	0.35%	165K	13.13M	55K	+50.00%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.35%	166.29K	13.24M	-1.71K	-1.02%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.37%	176.17K	14.02M	139.04K	+374.51%
Dec 31, 2023	JPMORGAN CHASE & CO	0.4%	189.91K	15.11M	17.45K	+10.12%
Dec 31, 2023	BARCLAYS PLC	0.41%	191.86K	15.27M	175.05K	+1,041.36%
Dec 31, 2023	NORGES BANK	0.41%	195.12K	15.53M	195.12K	+100.00%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.44%	205.82K	16.38M	46.57K	+29.24%
Dec 31, 2023	NUVEEN ASSET MANAGEMENT, LLC	0.5%	234.65K	18.68M	18.09K	+8.35%
Dec 31, 2023	WELLINGTON MANAGEMENT GROUP LLP	0.51%	239.82K	19.09M	239.82K	+100.00%
Dec 31, 2023	DRIEHAUS CAPITAL MANAGEMENT LLC	0.56%	265.84K	21.16M	16.95K	+6.81%
Dec 31, 2023		0.33%	155.35K	12.36M	155.35K	+100.00%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.63%	295.7K	23.53M	5.83K	+2.01%
Dec 31, 2023	TANG CAPITAL MANAGEMENT LLC	0.68%	320K	25.47M	0	0
Dec 31, 2023	NORTHERN TRUST CORP	0.73%	343.31K	27.32M	-5.75K	-1.65%
Dec 31, 2023	CITADEL ADVISORS LLC	0.24%	110.9K	8.83M	29.2K	+35.74%
Dec 31, 2023	EVENTIDE ASSET MANAGEMENT, LLC	0.74%	346.71K	27.59M	0	0
Dec 31, 2023	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.77%	365K	29.05M	40K	+12.31%
Dec 31, 2023	HOOD RIVER CAPITAL MANAGEMENT LLC	0.83%	392.75K	31.26M	9.48K	+2.47%
Dec 31, 2023	BOXER CAPITAL, LLC	0.85%	400K	31.84M	0	0
Dec 31, 2023	AVIDITY PARTNERS MANAGEMENT LP	0.98%	459.4K	36.56M	162.6K	+54.78%
Dec 31, 2023	PFM HEALTH SCIENCES, LP	0.99%	467.43K	37.2M	-55.78K	-10.66%
Dec 31, 2023	WOODLINE PARTNERS LP	1.19%	562.16K	44.74M	110.06K	+24.34%
Dec 31, 2023	MORGAN STANLEY	1.31%	619.38K	49.3M	320.96K	+107.55%
Dec 31, 2023	BELLEVUE GROUP AG	1.35%	635.37K	50.57M	3.89K	+0.62%
Dec 31, 2023	ALETHEA CAPITAL MANAGEMENT, LLC	1.6%	752.04K	59.86M	-6.75K	-0.89%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.75%	822.3K	65.45M	43.81K	+5.63%
Dec 31, 2023	POINT72 ASSET MANAGEMENT, L.P.	1.78%	837.2K	66.63M	305.26K	+57.39%
Dec 31, 2023	FMR LLC	1.87%	882.03K	70.2M	-976.53K	-52.54%
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	1.93%	909.97K	72.42M	406.92K	+80.89%
Dec 31, 2023	STATE STREET CORP	1.96%	924.19K	73.56M	56.54K	+6.52%
Dec 31, 2023	DEEP TRACK CAPITAL, LP	2.12%	1M	79.59M	-140.75K	-12.34%
Dec 31, 2023	RA CAPITAL MANAGEMENT, L.P.	2.12%	1M	79.59M	0	0
Dec 31, 2023	PERCEPTIVE ADVISORS LLC	2.2%	1.04M	82.62M	556.37K	+115.51%
Dec 31, 2023	BVF INC/IL	4.2%	1.98M	157.68M	-150K	-7.04%
Dec 31, 2023	FAIRMOUNT FUNDS MANAGEMENT LLC	5.01%	2.36M	187.84M	18.84K	+0.80%
Dec 31, 2023	BLACKROCK INC.	6.88%	3.24M	257.85M	305.26K	+10.40%
Dec 31, 2023	VANGUARD GROUP INC	7.85%	3.7M	294.23M	-32.36K	-0.87%
Dec 31, 2023	RTW INVESTMENTS, LP	9.53%	4.49M	357.33M	0	0
Sep 30, 2023	BLACKROCK INC.	6.72%	2.93M	-	210.95K	+7.75%
Sep 30, 2023	DEUTSCHE BANK AG\	0.14%	60.05K	-	2.41K	+4.18%
Sep 30, 2023	NATIONAL BANK OF CANADA /FI/	0.14%	60.2K	-	-9.22K	-13.28%
Sep 30, 2023	INVESCO LTD.	0.14%	62.44K	-	-109.13K	-63.61%
Sep 30, 2023	HENNION & WALSH ASSET MANAGEMENT, INC.	0.15%	67.05K	-	-10.39K	-13.42%
Sep 30, 2023	SCHONFELD STRATEGIC ADVISORS LLC	0.16%	67.7K	-	-7.61K	-10.11%
Sep 30, 2023	ATIKA CAPITAL MANAGEMENT LLC	0.16%	71K	-	-41K	-36.61%
Sep 30, 2023	SWISS NATIONAL BANK	0.16%	71.7K	-	-4.1K	-5.41%
Sep 30, 2023	PRIVIUM FUND MANAGEMENT B.V.	0.16%	72.03K	-	0	0
Sep 30, 2023	MOODY ALDRICH PARTNERS LLC	0.17%	73.63K	-	8.94K	+13.82%
Sep 30, 2023	WMS PARTNERS, LLC	0.18%	80.71K	-	711	+0.89%
Sep 30, 2023	LINDBROOK CAPITAL, LLC	0.19%	84.32K	-	-150	-0.18%
Sep 30, 2023	ARTIA GLOBAL PARTNERS LP	0.2%	87.85K	-	0	0
Sep 30, 2023	PEREGRINE CAPITAL MANAGEMENT LLC	0.21%	91.09K	-	-16.44K	-15.29%
Sep 30, 2023	ALTIUM CAPITAL MANAGEMENT LP	0.21%	92K	-	52K	+130.00%
Sep 30, 2023	WCM INVESTMENT MANAGEMENT, LLC	0.22%	95.96K	-	1.69K	+1.79%
Sep 30, 2023	HHLR ADVISORS, LTD.	0.23%	100K	-	0	0
Sep 30, 2023	CITIGROUP INC	0.24%	102.66K	-	39.9K	+63.58%
Sep 30, 2023	ALLSPRING GLOBAL INVESTMENTS HOLDINGS, LLC	0.24%	103.72K	-	1.11K	+1.08%
Sep 30, 2023	ALLY BRIDGE GROUP (NY) LLC	0.25%	110.6K	-	110.6K	+100.00%
Sep 30, 2023	PUTNAM INVESTMENTS LLC	0.28%	120.27K	-	2.96K	+2.52%
Sep 30, 2023	JANE STREET GROUP, LLC	0.29%	125.58K	-	-150.32K	-54.48%
Sep 30, 2023	US BANCORP \DE\	0.32%	138.77K	-	-961	-0.69%
Sep 30, 2023	TRI LOCUM PARTNERS LP	0.33%	142.51K	-	-57.57K	-28.77%
Sep 30, 2023	IRIDIAN ASSET MANAGEMENT LLC/CT	0.33%	145.03K	-	-167.38K	-53.58%
Sep 30, 2023	HSBC HOLDINGS PLC	0.34%	148.81K	-	148.81K	+100.00%
Sep 30, 2023	GOLDMAN SACHS GROUP INC	0.36%	159.25K	-	19.31K	+13.80%
Sep 30, 2023	BANK OF NEW YORK MELLON CORP	0.38%	168.01K	-	6.92K	+4.30%
Sep 30, 2023	NUVEEN ASSET MANAGEMENT, LLC	0.5%	216.56K	-	115.34K	+113.96%
Sep 30, 2023	SOLEUS CAPITAL MANAGEMENT, L.P.	0.54%	237.5K	-	212.6K	+853.82%
Sep 30, 2023	DRIEHAUS CAPITAL MANAGEMENT LLC	0.57%	248.89K	-	117	+0.05%
Sep 30, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.66%	289.87K	-	21.46K	+7.99%
Sep 30, 2023	AVIDITY PARTNERS MANAGEMENT LP	0.68%	296.8K	-	-248.2K	-45.54%
Sep 30, 2023	MORGAN STANLEY	0.68%	298.42K	-	-24.9K	-7.70%
Sep 30, 2023	RTW INVESTMENTS, LP	10.28%	4.49M	-	205.32K	+4.79%
Sep 30, 2023	EVENTIDE ASSET MANAGEMENT, LLC	0.79%	346.71K	-	346.71K	+100.00%
Sep 30, 2023	NORTHERN TRUST CORP	0.8%	349.06K	-	22.92K	+7.03%
Sep 30, 2023	NICHOLAS INVESTMENT PARTNERS, LP	0.9%	394.98K	-	96	+0.02%
Sep 30, 2023	WOODLINE PARTNERS LP	1.04%	452.11K	-	12.18K	+2.77%
Sep 30, 2023	PERCEPTIVE ADVISORS LLC	1.1%	481.65K	-	210.16K	+77.41%
Sep 30, 2023	POINT72 ASSET MANAGEMENT, L.P.	1.22%	531.94K	-	63.93K	+13.66%
Sep 30, 2023	JEFFERIES FINANCIAL GROUP INC.	1.27%	553.2K	-	553.2K	+100.00%
Sep 30, 2023	BELLEVUE GROUP AG	1.45%	631.49K	-	57.12K	+9.95%
Sep 30, 2023		1.48%	646.43K	-	646.43K	+100.00%
Sep 30, 2023	ALETHEA CAPITAL MANAGEMENT, LLC	1.74%	758.79K	-	-1.15K	-0.15%
Sep 30, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.78%	778.5K	-	68.73K	+9.68%
Sep 30, 2023	RA CAPITAL MANAGEMENT, L.P.	2.29%	1M	-	0	0
Sep 30, 2023	FMR LLC	4.26%	1.86M	-	-270.41K	-12.70%
Sep 30, 2023	BVF INC/IL	4.88%	2.13M	-	0	0
Sep 30, 2023	FAIRMOUNT FUNDS MANAGEMENT LLC	5.36%	2.34M	-	-3.74K	-0.16%

Insiders

Among the AXSM insiders holding of 15.7% of the stake in company, JEFFS ROGER, director, holds the largest shares of 57.51K. COLEMAN MARK, director, is the second largest AXSM insider with ownership of 47.14K shares. PIZZIE NICK, Chief Financial Officer, stands third with possession of 42.59K shares of that stake.

Insiders	Designation	Shares Held
JEFFS ROGER	director	57.51K
COLEMAN MARK	director	47.14K
PIZZIE NICK	Chief Financial Officer	42.59K
SAAD MARK E	director	10K
TABUTEAU HERRIOT	Chief Executive Officer	7.23K
KAYE RANDALL	Chief Medical Officer	6.02K
MAIZEL ARI	Chief Commercial Officer	0
MURDOCK HUNTER R.	General Counsel	0
JACOBSON MARK L.	Chief Operating Officer	0

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Feb 26, 2026	JACOBSON MARK L.	SALE	161.88	35.38K	5.73M	0
Feb 26, 2026	COLEMAN MARK	SALE	161.11	25K	4.03M	47.14K
Feb 02, 2026	TABUTEAU HERRIOT	SALE	185.60	32.41K	6.02M	7.23K
Jan 22, 2026	PIZZIE NICK	SALE	187.92	12K	2.26M	42.59K
Jan 21, 2026	MAIZEL ARI	SALE	184.44	7.5K	1.38M	0
Jan 07, 2026	TABUTEAU HERRIOT	SALE	170.38	31.26K	5.33M	7.23K
Jan 06, 2026	TABUTEAU HERRIOT	SALE	172.33	29.45K	5.08M	7.23K
Jan 05, 2026	TABUTEAU HERRIOT	SALE	171.28	78.7K	13.48M	7.23K
Dec 31, 2025	SAAD MARK E	SALE	165.18	31.35K	5.18M	10K
Dec 04, 2025	TABUTEAU HERRIOT	SALE	148.18	10.56K	1.56M	7.23K
Dec 03, 2025	TABUTEAU HERRIOT	SALE	146.94	20.16K	2.96M	7.23K
Dec 02, 2025	TABUTEAU HERRIOT	SALE	144.59	49.25K	7.12M	7.23K
Nov 05, 2025	TABUTEAU HERRIOT	SALE	134.49	21.78K	2.93M	7.23K
Nov 04, 2025	TABUTEAU HERRIOT	SALE	133.79	50.46K	6.75M	7.23K
Nov 03, 2025	TABUTEAU HERRIOT	SALE	132.34	91.71K	12.14M	7.23K
Oct 08, 2025	TABUTEAU HERRIOT	SALE	118.84	12.77K	1.52M	7.23K
Oct 07, 2025	TABUTEAU HERRIOT	SALE	118.77	13.39K	1.59M	7.23K
Oct 06, 2025	TABUTEAU HERRIOT	SALE	120.17	19.22K	2.31M	7.23K
Sep 22, 2025	JACOBSON MARK L.	SALE	115.96	10K	1.16M	0
Sep 16, 2025	JACOBSON MARK L.	SALE	114.23	40K	4.57M	0
Sep 16, 2025	TABUTEAU HERRIOT	SALE	114.19	19.72K	2.25M	7.23K
Sep 15, 2025	TABUTEAU HERRIOT	SALE	117.37	15.25K	1.79M	7.23K
Sep 12, 2025	TABUTEAU HERRIOT	SALE	118.96	27.91K	3.32M	7.23K
Sep 08, 2025	COLEMAN MARK	PURCHASE	127.20	800	101.76K	47.44K
Sep 05, 2025	SAAD MARK E	SALE	125.07	9.13K	1.14M	10K
Sep 02, 2025	JEFFS ROGER	SALE	123.68	13.46K	1.67M	57.51K
Aug 29, 2025	JEFFS ROGER	SALE	121.27	20K	2.43M	70.97K
Aug 28, 2025	JEFFS ROGER	SALE	121.60	20K	2.43M	90.97K
Aug 27, 2025	JEFFS ROGER	SALE	122.30	20K	2.45M	110.97K
Aug 26, 2025	JEFFS ROGER	SALE	120.03	20K	2.4M	130.97K
Aug 22, 2025	JEFFS ROGER	SALE	120.08	16.69K	2M	150.97K
Jun 23, 2025	MURDOCK HUNTER R.	SALE	100.12	6.01K	602.12K	0
Jun 20, 2025	MURDOCK HUNTER R.	SALE	102.47	7.5K	768.53K	0
Jun 18, 2025	MURDOCK HUNTER R.	SALE	100.90	7.5K	756.75K	0
Jun 17, 2025	MURDOCK HUNTER R.	SALE	100.26	7.5K	751.95K	0
Jun 16, 2025	MURDOCK HUNTER R.	SALE	102.42	7.5K	768.15K	0
Jun 09, 2025	JACOBSON MARK L.	SALE	110.44	25K	2.76M	5.78K
May 28, 2025	JACOBSON MARK L.	SALE	103.45	20K	2.07M	5.78K
May 28, 2025	COLEMAN MARK	SALE	103.43	3.75K	387.86K	46.64K
May 27, 2025	JACOBSON MARK L.	SALE	104.66	20.67K	2.16M	5.78K
May 27, 2025	COLEMAN MARK	SALE	105.47	3.75K	395.51K	50.39K
May 20, 2025	COLEMAN MARK	SALE	107.49	3K	322.47K	54.14K
Feb 14, 2025	PIZZIE NICK	SALE	131.07	3K	393.21K	42.19K
Feb 13, 2025	PIZZIE NICK	SALE	129.86	12K	1.56M	42.19K
Sep 11, 2024	SAAD MARK E	SALE	91.31	11.02K	1.01M	10K
Aug 09, 2024	JACOBSON MARK L.	SALE	84.26	47.74K	4.02M	5.78K
May 29, 2024	JACOBSON MARK L.	SALE	74.31	7.91K	587.81K	5.78K
May 29, 2024	COLEMAN MARK	SALE	75.14	5.25K	394.33K	14.6K
May 28, 2024	COLEMAN MARK	SALE	75.21	5.25K	394.77K	19.85K
Apr 01, 2024	JACOBSON MARK L.	SALE	77.24	24.66K	1.9M	0
Mar 15, 2024	JEFFS ROGER	SALE	71.61	2.35K	168.06K	120.76K
Mar 14, 2024	JEFFS ROGER	SALE	69.70	16.98K	1.18M	120.76K
Sep 15, 2023	COLEMAN MARK	SALE	75.19	11.02K	828.24K	25.1K
Nov 19, 2021	JEFFS ROGER	PURCHASE	37.30	3.95K	147.35K	120.76K
Nov 18, 2021	COLEMAN MARK	PURCHASE	35.07	409	14.34K	421.41K
Nov 18, 2021	PIZZIE NICK	PURCHASE	35.20	142	5K	142
Nov 17, 2021	SAAD MARK E	PURCHASE	34.40	100	3.44K	100
May 12, 2021	COLEMAN MARK	PURCHASE	58.15	500	29.08K	421K
Jun 29, 2020	PIZZIE NICK	PURCHASE	76.64	777	59.55K	41.22K
Jun 29, 2020	COLEMAN MARK	PURCHASE	78.50	650	51.03K	403.7K
Sep 26, 2019	PIZZIE NICK	PURCHASE	24.80	2.18K	54.06K	40.44K
Jun 26, 2019	COLEMAN MARK	PURCHASE	23.10	15.8K	364.98K	668.85K
Jun 25, 2019	COLEMAN MARK	PURCHASE	23.25	400	9.3K	653.05K
Jun 11, 2019	PIZZIE NICK	PURCHASE	20.80	1.92K	39.94K	1.92K
May 23, 2019	SAAD MARK E	PURCHASE	22.33	3.5K	78.16K	7K
May 13, 2019	COLEMAN MARK	PURCHASE	21.44	4.65K	99.7K	652.65K
Mar 19, 2019	COLEMAN MARK	PURCHASE	12.18	5.1K	62.12K	5.1K
Mar 19, 2019	PIZZIE NICK	PURCHASE	12.69	60	761.4	60
Jun 19, 2018	PIZZIE NICK	PURCHASE	3.05	400	1.22K	400
Dec 23, 2015	KAYE RANDALL	PURCHASE	9.03	1K	9.03K	6.02K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES685.22K23

NET SHARES-685.22K23

SHARES HELD215.39K23

% NET SHARES-418.13%0%

Frequently Asked Questions