How many institutions own ASND stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own ASND shares is 385, representing 106.15% of the company's common stock.

Who are the major shareholders selling Ascendis Pharma A/S stock?

TWO SIGMA INVESTMENTS, LP, in the last quarter, reduced its stake in ASND by -11.11% restricting it's holding to 220.34 thousand shares of worth nearly $50.40M. PRINCIPAL FINANCIAL GROUP INC also lessened -12.67% of the ASND shares from its portfolio, reducing its holding to 896.4 thousand shares of worth $205.03M. AMERICAN CENTURY COMPANIES INC also shunned ASND shares holding by -3.19% last quarter which brought its holding to 1.4 million shares worth $319.56M.

Investors who are buying ASND stock?

As per its latest 13F filing, PICTET ASSET MANAGEMENT HOLDING SA increased its stake in ASND by 243.01% in the last quarter. The institutional holder raised its holding to 251.83 thousand shares having worth more than $56.91M. BLACKROCK, INC. also added 5.23% more shares of ASND to its portfolio, raising its holding to 661.05 thousand shares of worth $151.20M. PERCEPTIVE ADVISORS LLC also increased its ASND shares holding by 41.61% which brought its holding to 1.53 million shares worth $350.28M.

ASND's major insiders: who are they?

The insider with the most stakes in ASND is SMITH SCOTT THOMAS , EVP & Chief Financial Officer at the company. Additionally, ASND stock is highly held by director BIENAIME JEAN JACQUES and See Remarks JENSEN FLEMMING STEEN among others.

Did an insider recently sell ASND stock?

Company executives, directors, and other insiders own 0.76% percent of Ascendis Pharma A/S's stock. Within the last six months, there have been 1 transaction(s) in which ASND insiders have sold stock, totaling 19.46K shares. Insiders that have sold shares include JENSEN FLEMMING STEEN.

Which insider recently purchased ASND stock?

There have been 4 transaction(s) during the past 6-months in which Ascendis Pharma A/S insiders have bought stock, totalling 750 shares

How much of ASND does insiders own?

Around 9.43K Ascendis Pharma A/S shares are held by insiders, which represents about 0.76% of ASND stock.

Who is the insider with the largest stake?

ASND EVP & Chief Financial Officer, SMITH SCOTT THOMAS holds the largest portfolio of the company's shares. ASND shares owned by SMITH total nearly 4.37 thousand.

Which institution holds the most shares in ASND?

TWO SIGMA INVESTMENTS, LP is the largest institutional owner in ASND which holds 220.34 thousand shares worth $50.40M or 0.36% of the total ASND shares outstanding followed by PICTET ASSET MANAGEMENT HOLDING SA with ownership of 251.83 thousand shares representing 0.41% of the ASND ownership. BLACKROCK, INC. is the third largest stakeholder with 661.05 thousand shares or 1.08% of the ownership worth more than $151.20M.

Is Ascendis Pharma A/S stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the ASND is concerned, it is a stock which is optionable.

Is there a short position on ASND's shares?

Number of ASND shares short is 1.72M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding ASND shares are there?

As of today, 65.58M shares of ASND are outstanding.

Is there many float in ASND stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, ASND has 62.11M shares in float.

ASND short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for ASND is 2.64.

Ascendis Pharma A/S (ASND) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares2.78

Short Percent Of Float3.34

Shares Outstanding65.58M

Shares Float62.11M

Shares Short1.72M

Short Ratio2.64

3.34%

Short % of Float

2.78%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

0.76% Percentage of Shares held by All Insiders

106.15% Percentage of Shares held by All Institutions

106.97% Percentage of Float held by Institutions

385

Number of Institutions Holding Shares

Institutional Ownership

About 106.15% of ASND shares are held by financial institutions. TWO SIGMA INVESTMENTS, LP is the top corporate investor, holding 220.34K shares valued at $50.40M. A 0.36% stake in Ascendis Pharma A/S is owned by the company. PICTET ASSET MANAGEMENT HOLDING SA owns 251.83K shares valued at $56.91M, which translates its holding of 0.41% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Mar 31, 2026	TWO SIGMA INVESTMENTS, LP	0.36%	220.34K	50.4M	-27.55K	-11.11%
Mar 31, 2026	PICTET ASSET MANAGEMENT HOLDING SA	0.41%	251.83K	56.91M	178.42K	+243.01%
Mar 31, 2026	BLACKROCK, INC.	1.08%	661.05K	151.2M	32.85K	+5.23%
Mar 31, 2026	PRINCIPAL FINANCIAL GROUP INC	1.46%	896.4K	205.03M	-130.01K	-12.67%
Mar 31, 2026	AMERICAN CENTURY COMPANIES INC	2.28%	1.4M	319.56M	-46.02K	-3.19%
Mar 31, 2026	PERCEPTIVE ADVISORS LLC	2.5%	1.53M	350.28M	450K	+41.61%
Mar 31, 2026	AMERIPRISE FINANCIAL INC	0.67%	411.5K	94.12M	411.5K	+100.00%
Mar 31, 2026	RICE HALL JAMES & ASSOCIATES, LLC	0.24%	148.39K	33.94M	3.34K	+2.30%
Mar 31, 2026	PFM HEALTH SCIENCES, LP	0.25%	152.03K	34.77M	-25.65K	-14.44%
Mar 31, 2026	WELLS FARGO & COMPANY/MN	0.25%	154.2K	35.27M	120.42K	+356.48%
Mar 31, 2026	ALLSPRING GLOBAL INVESTMENTS HOLDINGS, LLC	0.3%	184.22K	42.05M	-3.42K	-1.82%
Mar 31, 2026	WESTFIELD CAPITAL MANAGEMENT CO LP	7.84%	4.81M	1.1B	-372.26K	-7.18%
Mar 31, 2026	UBS GROUP AG	0.34%	207.34K	47.42M	-100.85K	-32.72%
Mar 31, 2026	ABRDN PLC	0.34%	210.15K	48.07M	-11.52K	-5.20%
Mar 31, 2026	CAPITAL WORLD INVESTORS	1.47%	900.52K	205.98M	900.52K	+100.00%
Mar 31, 2026	KENNEDY CAPITAL MANAGEMENT LLC	0.04%	23.84K	5.45M	3.98K	+20.02%
Mar 31, 2026	CAPITAL INTERNATIONAL SARL	0.04%	24.75K	5.66M	-194	-0.78%
Mar 31, 2026	MATISSE CAPITAL	0.04%	26.08K	5.96M	-1.23K	-4.50%
Mar 31, 2026	WALLEYE TRADING LLC	0.05%	29.1K	6.66M	7.2K	+32.88%
Mar 31, 2026	CITIGROUP INC	0.05%	29.7K	6.79M	-1.14K	-3.70%
Mar 31, 2026	FIRST TRUST ADVISORS LP	0.05%	31.14K	7.12M	18.91K	+154.58%
Mar 31, 2026	DIVERSIFIED TRUST CO	0.06%	37.16K	8.5M	-5.09K	-12.05%
Mar 31, 2026	RUSSELL INVESTMENTS GROUP, LTD.	0.07%	40.27K	9.21M	5.36K	+15.34%
Mar 31, 2026	NOMURA ASSET MANAGEMENT CO LTD	0.07%	43.48K	9.95M	-217	-0.50%
Mar 31, 2026	NORTHERN TRUST CORP	0.07%	44.97K	10.29M	12.12K	+36.88%
Mar 31, 2026	VOYA INVESTMENT MANAGEMENT LLC	0.07%	45.59K	10.43M	-11.49K	-20.12%
Mar 31, 2026	PEAK6 LLC	0.08%	50K	11.44M	0	0
Mar 31, 2026		0.06%	38.67K	8.84M	38.67K	+100.00%
Mar 31, 2026	JANE STREET GROUP, LLC	0.11%	66.4K	15.19M	-7.2K	-9.78%
Mar 31, 2026	SCHRODER INVESTMENT MANAGEMENT GROUP	0.11%	67.9K	14.83M	-5.41K	-7.38%
Mar 31, 2026	SYNERGY ASSET MANAGEMENT, LLC	0.11%	70.46K	16.12M	70.46K	+100.00%
Mar 31, 2026	LOOMIS SAYLES & CO L P	0.13%	80.41K	18.39M	-31.84K	-28.36%
Mar 31, 2026	ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	0.15%	91.47K	20.92M	91.47K	+100.00%
Mar 31, 2026	AFFINITY ASSET ADVISORS, LLC	0.15%	95K	21.73M	65K	+216.67%
Mar 31, 2026	PERPETUAL LTD	0.16%	100.64K	23.02M	100.64K	+100.00%
Mar 31, 2026	RENAISSANCE TECHNOLOGIES LLC	0.19%	117.33K	26.84M	117.33K	+100.00%
Mar 31, 2026	SG AMERICAS SECURITIES, LLC	0.2%	120.79K	27.63M	109.58K	+977.23%
Mar 31, 2026	SILVERARC CAPITAL MANAGEMENT, LLC	0.2%	124.66K	28.51M	75.43K	+153.23%
Mar 31, 2026	WELLINGTON MANAGEMENT GROUP LLP	2.86%	1.76M	402.02M	-5.09K	-0.29%
Mar 31, 2026	MASSACHUSETTS FINANCIAL SERVICES CO /MA/	3.03%	1.86M	425.57M	-25.72K	-1.36%
Mar 31, 2026	FRED ALGER MANAGEMENT, LLC	0.5%	304.9K	69.74M	-47.21K	-13.41%
Mar 31, 2026	BNP PARIBAS ARBITRAGE, SNC	0.5%	309.17K	70.72M	2.09K	+0.68%
Mar 31, 2026	MACQUARIE MANAGEMENT HOLDINGS, INC.	0.91%	556.43K	127.27M	59.59K	+11.99%
Mar 31, 2026	BANK OF NEW YORK MELLON CORP	0.37%	228.68K	52.3M	34.07K	+17.51%
Mar 31, 2026	CANDRIAM S.C.A.	0.38%	230.28K	52.67M	43.34K	+23.18%
Mar 31, 2026	SEI INVESTMENTS CO	0.57%	351.15K	80.32M	69.67K	+24.75%
Mar 31, 2026	GOLDMAN SACHS GROUP INC	0.92%	566.19K	129.51M	-30.51K	-5.11%
Mar 31, 2026	FRANKLIN RESOURCES INC	3.34%	2.05M	469.34M	141.87K	+7.43%
Mar 31, 2026	FMR LLC	6.32%	3.88M	886.69M	-276.71K	-6.66%
Mar 31, 2026	SPYGLASS CAPITAL MANAGEMENT LLC	0.6%	367.97K	84.17M	-47.58K	-11.45%
Mar 31, 2026	VESTAL POINT CAPITAL, LP	0.61%	375K	85.77M	200K	+114.29%
Mar 31, 2026	FIL LTD	0.73%	447.42K	102.34M	-31.22K	-6.52%
Mar 31, 2026	TD ASSET MANAGEMENT INC	0.36%	217.99K	49.86M	-16.02K	-6.85%
Mar 31, 2026	MORGAN STANLEY	0.99%	606.35K	138.69M	-11.62K	-1.88%
Mar 31, 2026	INVESCO LTD.	0.59%	362.11K	82.83M	-223.99K	-38.22%
Mar 31, 2026	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.5%	305.5K	69.88M	108.7K	+55.23%
Mar 31, 2026	CAPTION MANAGEMENT, LLC	0.4%	247K	56.5M	17K	+7.39%
Mar 31, 2026	ARS INVESTMENT PARTNERS, LLC	0.34%	209.46K	47.91M	34.85K	+19.96%
Mar 31, 2026	ORBIMED ADVISORS LLC	0.3%	181.98K	41.62M	10K	+5.81%
Mar 31, 2026	NEW YORK STATE COMMON RETIREMENT FUND	0.28%	171.11K	39.14M	-11.12K	-6.10%
Mar 31, 2026	LORD, ABBETT & CO. LLC	0.24%	145.32K	33.24M	25.12K	+20.90%
Mar 31, 2026	ALLIANCEBERNSTEIN L.P.	0.45%	278.2K	59.32M	-10.39K	-3.60%
Mar 31, 2026	ARTISAN PARTNERS LIMITED PARTNERSHIP	5.26%	3.23M	738.84M	4.3K	+0.13%
Mar 31, 2026	CAPITAL INTERNATIONAL INVESTORS	3.19%	1.96M	448.05M	-1.11M	-36.07%
Mar 31, 2026	BANK OF AMERICA CORP /DE/	0.32%	198.51K	45.4M	36K	+22.15%
Mar 31, 2026	ROCK SPRINGS CAPITAL MANAGEMENT LP	0.32%	194K	44.37M	-9.5K	-4.67%
Mar 31, 2026	MILLENNIUM MANAGEMENT LLC	0.31%	189.03K	43.24M	-73.3K	-27.94%
Mar 31, 2026	RA CAPITAL MANAGEMENT, L.P.	16.75%	10.28M	2.35B	0	0
Mar 31, 2026	AVORO CAPITAL ADVISORS LLC	8.25%	5.06M	1.16B	-48.61K	-0.95%
Mar 31, 2026	DEUTSCHE BANK AG\	0.22%	135.19K	30.92M	-161.63K	-54.45%
Mar 31, 2026	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	0.22%	133.33K	30.5M	0	0
Mar 31, 2026	BRAUN STACEY ASSOCIATES INC	0.21%	130.99K	29.96M	11.9K	+9.99%
Mar 31, 2026	POLAR CAPITAL HOLDINGS PLC	1.06%	651.71K	149.07M	281.24K	+75.91%
Mar 31, 2026	JPMORGAN CHASE & CO	0.88%	539.43K	117.79M	32.19K	+6.35%
Mar 31, 2026	TRI LOCUM PARTNERS LP	0.42%	255.33K	58.4M	-9.68K	-3.65%
Dec 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.51%	307.09K	65.48M	68.56K	+28.74%
Dec 31, 2025	MACQUARIE MANAGEMENT HOLDINGS, INC.	0.82%	496.84K	105.95M	496.84K	+100.00%
Dec 31, 2025	CITADEL ADVISORS LLC	0.86%	519.52K	110.78M	491.88K	+1,779.58%
Dec 31, 2025	LOOMIS SAYLES & CO L P	0.18%	112.24K	23.93M	-41.17K	-26.83%
Dec 31, 2025	WESTFIELD CAPITAL MANAGEMENT CO LP	8.5%	5.19M	1.11B	-74.21K	-1.41%
Dec 31, 2025	ABRDN PLC	0.36%	221.68K	47.27M	172.25K	+348.50%
Dec 31, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.09%	57.08K	12.17M	-16.13K	-22.03%
Dec 31, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.08%	49.23K	10.5M	-4.33K	-8.08%
Dec 31, 2025	NOMURA ASSET MANAGEMENT CO LTD	0.07%	43.7K	9.32M	15.95K	+57.48%
Dec 31, 2025	VICTORY CAPITAL MANAGEMENT INC	0.07%	43.19K	9.21M	-165.74K	-79.33%
Dec 31, 2025	DIVERSIFIED TRUST CO	0.07%	42.25K	9.01M	-3.43K	-7.51%
Dec 31, 2025	SKANDINAVISKA ENSKILDA BANKEN AB (PUBL)	0.06%	38.99K	8.31M	10.22K	+35.54%
Dec 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.32%	196.8K	41.97M	79.9K	+68.35%
Dec 31, 2025	JAIN GLOBAL LLC	0.36%	216.53K	46.17M	180.56K	+502.10%
Dec 31, 2025	CAPTION MANAGEMENT, LLC	0.38%	230K	49.05M	124.4K	+117.80%
Dec 31, 2025	TD ASSET MANAGEMENT INC	0.38%	234.01K	49.9M	-62.33K	-21.03%
Dec 31, 2025	SIREN, L.L.C.	0.39%	235.86K	50.3M	0	0
Dec 31, 2025	TWO SIGMA INVESTMENTS, LP	0.41%	247.89K	52.86M	64.01K	+34.81%
Dec 31, 2025	MILLENNIUM MANAGEMENT LLC	0.43%	262.33K	55.94M	87.73K	+50.24%
Dec 31, 2025	FRED ALGER MANAGEMENT, LLC	0.58%	352.11K	75.08M	181.41K	+106.27%
Dec 31, 2025	JPMORGAN CHASE & CO	0.83%	507.24K	108.16M	214.84K	+73.48%
Dec 31, 2025	GOLDMAN SACHS GROUP INC	0.98%	596.7K	127.24M	-56.31K	-8.62%
Dec 31, 2025	UBS GROUP AG	0.51%	308.19K	65.72M	112.99K	+57.88%
Dec 31, 2025	MORGAN STANLEY	1.02%	617.97K	131.78M	211.21K	+51.92%
Dec 31, 2025	CASTLEARK MANAGEMENT LLC	0.11%	66.34K	14.15M	23.68K	+55.51%
Dec 31, 2025	STATE STREET CORP	0.11%	67.95K	14.49M	6.41K	+10.42%
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.11%	68.86K	14.68B	807	+1.19%
Dec 31, 2025	ENSIGN PEAK ADVISORS, INC	0.11%	69.56K	14.83M	-1.16K	-1.65%
Dec 31, 2025	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	0.12%	72.11K	15.38M	-117.55K	-61.98%
Dec 31, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.12%	73.42K	15.49M	-3.64K	-4.72%
Dec 31, 2025	SCHRODER INVESTMENT MANAGEMENT GROUP	0.12%	73.31K	15.63M	39.92K	+119.55%
Dec 31, 2025	JANE STREET GROUP, LLC	0.12%	73.6K	15.69B	0	0
Dec 31, 2025	CITIGROUP INC	0.12%	75.9K	16.18M	75.9K	+100.00%
Dec 31, 2025	BECK BODE, LLC	0.13%	81.09K	17.29M	81.09K	+100.00%
Dec 31, 2025		0.14%	85.69K	18.27B	85.69K	+100.00%
Dec 31, 2025	BAROMETER CAPITAL MANAGEMENT INC.	0.15%	91.39K	10.84M	87.49K	+2,240.98%
Dec 31, 2025	1832 ASSET MANAGEMENT L.P.	0.18%	110K	23.46M	0	0
Dec 31, 2025	ALLSPRING GLOBAL INVESTMENTS HOLDINGS, LLC	0.31%	187.64K	40.02M	-4.03K	-2.10%
Dec 31, 2025	IMC-CHICAGO, LLC	0.19%	113.68K	24.24M	113.68K	+100.00%
Dec 31, 2025	BRAUN STACEY ASSOCIATES INC	0.2%	119.1K	25.4M	25.15K	+26.77%
Dec 31, 2025	LORD, ABBETT & CO. LLC	0.2%	120.2K	25.63M	-31.23K	-20.62%
Dec 31, 2025	FIRST TURN MANAGEMENT, LLC	0.22%	131.81K	28.11M	-14.48K	-9.90%
Dec 31, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	0.22%	133.33K	28.43M	0	0
Dec 31, 2025	BANK OF AMERICA CORP /DE/	0.27%	162.5K	34.65B	14.49K	+9.79%
Dec 31, 2025	ARS INVESTMENT PARTNERS, LLC	0.29%	174.61K	37.23M	-1.06K	-0.60%
Dec 31, 2025	BLACKROCK, INC.	1.04%	628.2K	133.96M	176.7K	+39.14%
Dec 31, 2025	PRINCIPAL FINANCIAL GROUP INC	1.68%	1.03M	218.87M	232.73K	+29.32%
Dec 31, 2025	PEAK6 LLC	0.08%	50K	10.66M	50K	+100.00%
Dec 31, 2025	CHEVY CHASE TRUST HOLDINGS, LLC	0.09%	56.7K	12.09M	56.7K	+100.00%
Dec 31, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.1%	60.9K	12.75M	-5.32K	-8.03%
Dec 31, 2025	AMERICAN CENTURY COMPANIES INC	2.38%	1.44M	307.74M	898.54K	+164.99%
Dec 31, 2025	MASSACHUSETTS FINANCIAL SERVICES CO /MA/	3.09%	1.89M	402.25M	3.61K	+0.19%
Dec 31, 2025	FRANKLIN RESOURCES INC	3.13%	1.91M	407.31M	320.12K	+20.13%
Dec 31, 2025	CAPITAL INTERNATIONAL INVESTORS	5.02%	3.06M	653.36M	3.33K	+0.11%
Dec 31, 2025	PERCEPTIVE ADVISORS LLC	1.78%	1.08M	230.6M	-7.08K	-0.65%
Dec 31, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.3%	182.23K	38.86M	12.34K	+7.26%
Dec 31, 2025	CANDRIAM S.C.A.	0.31%	186.94K	39.86M	7.98K	+4.46%
Dec 31, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.32%	193.46K	41.25M	-96.71K	-33.33%
Dec 31, 2025	INVESCO LTD.	0.97%	586.09K	124.98M	-331.81K	-36.15%
Dec 31, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	2.75%	1.67M	355.61M	-998.99K	-37.46%
Dec 31, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	0.34%	203.5K	43.39M	-11K	-5.13%
Dec 31, 2025	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.36%	216.17K	46.1M	-18.22K	-7.77%
Dec 31, 2025	ALLIANCEBERNSTEIN L.P.	0.48%	288.59K	61.54M	-87.31K	-23.23%
Dec 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	2.59%	1.57M	334.84M	-155.97K	-9.04%
Dec 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	2.91%	1.76M	375.88M	-36.21K	-2.01%
Dec 31, 2025	ARTISAN PARTNERS LIMITED PARTNERSHIP	5.32%	3.23M	687.89M	-495K	-13.30%
Dec 31, 2025	Q GLOBAL ADVISORS, LLC	0.31%	190K	40.52M	20K	+11.76%
Dec 31, 2025	POLAR CAPITAL HOLDINGS PLC	0.61%	370.47K	79M	-487.44K	-56.82%
Dec 31, 2025	SPYGLASS CAPITAL MANAGEMENT LLC	0.69%	415.55K	88.61M	26.9K	+6.92%
Dec 31, 2025	FIL LTD	0.79%	478.64K	102.07M	19.3K	+4.20%
Dec 31, 2025	AMERIPRISE FINANCIAL INC	0.91%	550.48K	117.38M	-12.46K	-2.21%
Dec 31, 2025	JANUS HENDERSON GROUP PLC	6.7%	4.06M	866.1M	-261.42K	-6.05%
Dec 31, 2025	FMR LLC	6.85%	4.15M	885.65M	-318.42K	-7.12%
Dec 31, 2025	AVORO CAPITAL ADVISORS LLC	8.38%	5.11M	1.09B	1.11K	+0.02%
Dec 31, 2025	RA CAPITAL MANAGEMENT, L.P.	16.96%	10.28M	2.19B	0	0
Dec 31, 2025	TRI LOCUM PARTNERS LP	0.44%	265.02K	56.51M	90.19K	+51.59%
Dec 31, 2025	SEI INVESTMENTS CO	0.46%	281.47K	60.02M	76.15K	+37.09%
Dec 31, 2025	DEUTSCHE BANK AG\	0.49%	296.82K	63.29M	227.26K	+326.71%
Dec 31, 2025	BANK OF NEW YORK MELLON CORP	0.32%	194.61K	41.5M	-14.69K	-7.02%
Sep 30, 2025	ORBIMED ADVISORS LLC	0.32%	191.91K	38.15M	157.51K	+457.86%
Sep 30, 2025	UBS GROUP AG	0.32%	195.2K	38.81M	112.44K	+135.87%
Sep 30, 2025	SEI INVESTMENTS CO	0.34%	205.32K	40.82M	-31.25K	-13.21%
Sep 30, 2025	VICTORY CAPITAL MANAGEMENT INC	0.35%	208.93K	41.54M	-10.19K	-4.65%
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.35%	209.3K	41.61M	91.68K	+77.95%
Sep 30, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	0.35%	214.5K	42.64M	-2.5K	-1.15%
Sep 30, 2025	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.39%	234.4K	46.6M	-28.87K	-10.97%
Sep 30, 2025	BLACKROCK, INC.	0.75%	451.5K	89.76M	-20.23K	-4.29%
Sep 30, 2025	FIL LTD	0.76%	459.34K	91.32M	-4.76K	-1.02%
Sep 30, 2025	AMERICAN CENTURY COMPANIES INC	0.9%	544.61K	108.27M	13.8K	+2.60%
Sep 30, 2025	AMERIPRISE FINANCIAL INC	0.93%	562.94K	111.92M	-25.13K	-4.27%
Sep 30, 2025	VESTAL POINT CAPITAL, LP	0.99%	600K	119.29M	400K	+200.00%
Sep 30, 2025	MASSACHUSETTS FINANCIAL SERVICES CO /MA/	3.11%	1.88M	374.32M	-19.06K	-1.00%
Sep 30, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	4.41%	2.67M	530.15M	-916.93K	-25.59%
Sep 30, 2025	CAPITAL INTERNATIONAL INVESTORS	5.06%	3.06M	608.48M	13.69K	+0.45%
Sep 30, 2025	ARTISAN PARTNERS LIMITED PARTNERSHIP	6.15%	3.72M	739.75M	-269.54K	-6.75%
Sep 30, 2025	LOMBARD ODIER ASSET MANAGEMENT (EUROPE) LTD	7.06%	4.27M	5.83M	4.27M	+100.00%
Sep 30, 2025	JANUS HENDERSON GROUP PLC	7.15%	4.32M	859.42M	-104.73K	-2.37%
Sep 30, 2025	FMR LLC	7.4%	4.47M	889.03M	-59.99K	-1.32%
Sep 30, 2025	RA CAPITAL MANAGEMENT, L.P.	17.01%	10.28M	2.04B	0	0
Sep 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.28%	169.89K	33.78M	-12.66K	-6.94%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.39%	238.53K	47.42M	72.86K	+43.98%
Sep 30, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.48%	290.17K	57.69M	89.13K	+44.33%
Sep 30, 2025	JPMORGAN CHASE & CO	0.48%	292.4K	58.13M	84.26K	+40.48%
Sep 30, 2025	SIREN, L.L.C.	0.39%	235.86K	46.89M	-10.08K	-4.10%
Sep 30, 2025	TD ASSET MANAGEMENT INC	0.49%	296.35K	58.92M	4.26K	+1.46%
Sep 30, 2025	MACQUARIE GROUP LTD	0.51%	309.54K	61.54M	192.8K	+165.16%
Sep 30, 2025	AVORO CAPITAL ADVISORS LLC	8.45%	5.11M	1.02B	130K	+2.61%
Sep 30, 2025	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	0.31%	189.65K	37.71M	-87.33K	-31.53%
Sep 30, 2025	TWO SIGMA INVESTMENTS, LP	0.3%	183.89K	36.56M	180.77K	+5,803.24%
Sep 30, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	0.3%	179.17K	35.62M	-15.94K	-8.17%
Sep 30, 2025	ARS INVESTMENT PARTNERS, LLC	0.29%	175.67K	34.92M	-34.26K	-16.32%
Sep 30, 2025	TRI LOCUM PARTNERS LP	0.29%	174.83K	34.76M	27.19K	+18.41%
Sep 30, 2025	MILLENNIUM MANAGEMENT LLC	0.29%	174.6K	34.71M	101.72K	+139.55%
Sep 30, 2025	FRED ALGER MANAGEMENT, LLC	0.28%	170.7K	33.94M	166.91K	+4,398.05%
Sep 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	2.86%	1.73M	343.19M	-149.26K	-7.96%
Sep 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	2.98%	1.8M	357.65M	880.84K	+95.94%
Sep 30, 2025	MORGAN STANLEY	0.67%	406.76K	80.87M	151.98K	+59.65%
Sep 30, 2025	FRANKLIN RESOURCES INC	2.63%	1.59M	316.1M	-163.51K	-9.33%
Sep 30, 2025	PERCEPTIVE ADVISORS LLC	1.8%	1.09M	216.4M	124.62K	+12.93%
Sep 30, 2025	INVESCO LTD.	1.52%	917.9K	182.49M	-29.32K	-3.10%
Sep 30, 2025	WESTFIELD CAPITAL MANAGEMENT CO LP	8.7%	5.26M	1.05B	-191.49K	-3.51%
Sep 30, 2025	ENVESTNET ASSET MANAGEMENT INC	0.04%	24.96K	4.96M	3.23K	+14.87%
Sep 30, 2025	MATISSE CAPITAL	0.04%	26.02K	5.17M	-1.92K	-6.88%
Sep 30, 2025	CANADA PENSION PLAN INVESTMENT BOARD	0.04%	26.53K	5.27M	26.53K	+100.00%
Sep 30, 2025	NOMURA ASSET MANAGEMENT CO LTD	0.05%	27.75K	5.52M	2.11K	+8.21%
Sep 30, 2025	SKANDINAVISKA ENSKILDA BANKEN AB (PUBL)	0.05%	28.77K	5.72M	28.77K	+100.00%
Sep 30, 2025	DEKABANK DEUTSCHE GIROZENTRALE	0.05%	30K	5.71M	0	0
Sep 30, 2025	CAPITAL INTERNATIONAL SARL	0.05%	30.86K	6.14M	2.7K	+9.59%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0.05%	31.67K	6.3M	179	+0.57%
Sep 30, 2025	SCHRODER INVESTMENT MANAGEMENT GROUP	0.06%	33.39K	6.64M	-23.6K	-41.41%
Sep 30, 2025	EMPOWERED FUNDS, LLC	0.06%	36.08K	7.17M	2.88K	+8.68%
Sep 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0.07%	41.46K	8.24M	12.09K	+41.18%
Sep 30, 2025	DIVERSIFIED TRUST CO	0.08%	45.68K	9.08M	263	+0.58%
Sep 30, 2025	ABRDN PLC	0.08%	49.43K	9.83M	-90.18K	-64.60%
Sep 30, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.09%	53.55K	10.65M	-33K	-38.13%
Sep 30, 2025	ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	0.1%	60.66K	12.06M	60.66K	+100.00%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.11%	68.05K	13.53M	7.24K	+11.91%
Sep 30, 2025	DEUTSCHE BANK AG\	0.12%	69.56K	13.83M	39.83K	+133.96%
Sep 30, 2025	ENSIGN PEAK ADVISORS, INC	0.12%	70.72K	14.06M	9K	+14.58%
Sep 30, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.12%	73.21K	14.55M	39.88K	+119.67%
Sep 30, 2025	HUDSON BAY CAPITAL MANAGEMENT LP	0.13%	78.93K	15.69M	78.93K	+100.00%
Sep 30, 2025	BRAUN STACEY ASSOCIATES INC	0.16%	93.95K	18.68M	93.95K	+100.00%
Sep 30, 2025	RICE HALL JAMES & ASSOCIATES, LLC	0.24%	147.09K	29.24M	-13.02K	-8.13%
Sep 30, 2025	LORD, ABBETT & CO. LLC	0.25%	151.43K	30.11M	-2.75K	-1.78%
Sep 30, 2025	POLAR CAPITAL HOLDINGS PLC	1.42%	857.91K	170.56M	20.13K	+2.40%
Sep 30, 2025	LOOMIS SAYLES & CO L P	0.25%	153.41K	30.5M	4.91K	+3.31%
Sep 30, 2025	PRINCIPAL FINANCIAL GROUP INC	1.31%	793.68K	157.79M	765.56K	+2,722.87%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	1.08%	653.01K	129.83M	114.73K	+21.31%
Sep 30, 2025	GROUPAMA ASSET MANAGMENT	0.66%	400K	534.74K	0	0
Sep 30, 2025	SPYGLASS CAPITAL MANAGEMENT LLC	0.64%	388.65K	77.27M	388.65K	+100.00%
Sep 30, 2025	ALLIANCEBERNSTEIN L.P.	0.62%	375.9K	74.73M	-1.8K	-0.48%
Sep 30, 2025	CANDRIAM S.C.A.	0.3%	178.96K	35.58M	-16.16K	-8.28%
Sep 30, 2025	Q GLOBAL ADVISORS, LLC	0.28%	170K	33.8M	-85K	-33.33%
Sep 30, 2025	RESOLUTE CAPITAL ASSET PARTNERS LLC	0.27%	165.67K	32.94M	5K	+3.11%
Sep 30, 2025	ALLSPRING GLOBAL INVESTMENTS HOLDINGS, LLC	0.32%	191.67K	39.12M	-8.59K	-4.29%
Jun 30, 2025	VICTORY CAPITAL MANAGEMENT INC	0.37%	219.12K	37.82M	94.19K	+75.40%
Jun 30, 2025	RA CAPITAL MANAGEMENT, L.P.	17.13%	10.28M	1.77B	0	0
Jun 30, 2025	FMR LLC	7.55%	4.53M	782.18M	-141.22K	-3.02%
Jun 30, 2025	MASSACHUSETTS FINANCIAL SERVICES CO /MA/	3.17%	1.9M	328.26M	23.93K	+1.27%
Jun 30, 2025	INVESCO LTD.	1.58%	947.23K	163.49M	-251.25K	-20.96%
Jun 30, 2025	CITADEL ADVISORS LLC	0.98%	587.34K	101.38B	-537.84K	-47.80%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.9%	538.29K	92.91B	-47.29K	-8.08%
Jun 30, 2025	ALLIANCEBERNSTEIN L.P.	0.63%	377.7K	65.19B	-54.4K	-12.59%
Jun 30, 2025	MORGAN STANLEY	0.42%	254.79K	43.98B	-1.65M	-86.62%
Jun 30, 2025	ALLSPRING GLOBAL INVESTMENTS HOLDINGS, LLC	0.33%	200.26K	34.44M	10.64K	+5.61%
Jun 30, 2025	VESTAL POINT CAPITAL, LP	0.33%	200K	34.52M	49.86K	+33.21%
Jun 30, 2025		0.3%	179.93K	31.06M	-15.6K	-7.98%
Jun 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.28%	165.67K	28.59M	23.04K	+16.16%
Jun 30, 2025	LORD, ABBETT & CO. LLC	0.26%	154.18K	26.61M	154.18K	+100.00%
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	3.12%	1.88M	323.71M	-380.61K	-16.87%
Jun 30, 2025	PERCEPTIVE ADVISORS LLC	1.61%	963.89K	166.37M	963.89K	+100.00%
Jun 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	1.53%	918.1K	158.46M	330.33K	+56.20%
Jun 30, 2025	AMERIPRISE FINANCIAL INC	0.98%	588.07K	101.5M	-91.87K	-13.51%
Jun 30, 2025	AMERICAN CENTURY COMPANIES INC	0.88%	530.81K	91.62M	68.64K	+14.85%
Jun 30, 2025	BLACKROCK, INC.	0.79%	471.73K	81.42M	-45.43K	-8.78%
Jun 30, 2025	ARS INVESTMENT PARTNERS, LLC	0.35%	209.93K	36.23M	-55.23K	-20.83%
Jun 30, 2025	JPMORGAN CHASE & CO	0.35%	208.14K	35.93M	23.02K	+12.43%
Jun 30, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.34%	201.04K	34.7M	91.41K	+83.38%
Jun 30, 2025	CANDRIAM S.C.A.	0.33%	195.12K	33.68M	-47.65K	-19.63%
Jun 30, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	0.33%	195.11K	33.68M	43.28K	+28.51%
Jun 30, 2025	WESTFIELD CAPITAL MANAGEMENT CO LP	9.08%	5.45M	940.91M	-27.86K	-0.51%
Jun 30, 2025	AVORO CAPITAL ADVISORS LLC	8.3%	4.98M	859.55M	-238K	-4.56%
Jun 30, 2025	JANUS HENDERSON GROUP PLC	7.38%	4.43M	764.39M	-59.16K	-1.32%
Jun 30, 2025	ARTISAN PARTNERS LIMITED PARTNERSHIP	6.65%	3.99M	688.75M	-266.2K	-6.25%
Jun 30, 2025	CAPITAL INTERNATIONAL INVESTORS	5.08%	3.05M	525.9M	172.14K	+5.99%
Jun 30, 2025	FRANKLIN RESOURCES INC	2.92%	1.75M	302.65M	113.35K	+6.91%
Jun 30, 2025	GROUPAMA ASSET MANAGMENT	0.67%	400K	505.76K	0	0
Jun 30, 2025	WOODLINE PARTNERS LP	0.51%	305.45K	52.72M	648	+0.21%
Jun 30, 2025	TD ASSET MANAGEMENT INC	0.49%	292.09K	50.41M	-51.3K	-14.94%
Jun 30, 2025	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	0.46%	276.98K	47.81M	-53.17K	-16.10%
Jun 30, 2025	SIREN, L.L.C.	0.41%	245.94K	42.45M	-41.42K	-14.41%
Jun 30, 2025	SEI INVESTMENTS CO	0.39%	236.57K	40.83M	-21.44K	-8.31%
Jun 30, 2025	FIL LTD	0.77%	464.1K	80.1M	1.73K	+0.37%
Jun 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.77%	459.61K	79.33M	132.2K	+40.38%
Jun 30, 2025	FIRST TURN MANAGEMENT, LLC	0.22%	134.69K	23.25M	21.41K	+18.90%
Jun 30, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	0.22%	133.33K	23.01M	0	0
Jun 30, 2025	CATALIO CAPITAL MANAGEMENT, LP	0.3%	179.93K	31.06M	-15.6K	-7.98%
Jun 30, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	5.97%	3.58M	618.52M	529.72K	+17.35%
Jun 30, 2025	POLAR CAPITAL HOLDINGS PLC	1.4%	837.78K	144.6M	312.78K	+59.58%
Jun 30, 2025	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.44%	263.27K	45.44M	-82.75K	-23.92%
Jun 30, 2025	Q GLOBAL ADVISORS, LLC	0.42%	255K	44.01M	6.11K	+2.46%
Jun 30, 2025	CAMBER CAPITAL MANAGEMENT LP	0.42%	250K	43.15M	-100K	-28.57%
Jun 30, 2025	PFM HEALTH SCIENCES, LP	0.37%	221.75K	38.27M	34.84K	+18.64%
Jun 30, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	0.36%	217K	37.45M	1K	+0.46%
Jun 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.3%	182.56K	31.51M	-21.92K	-10.72%
Jun 30, 2025	RESOLUTE CAPITAL ASSET PARTNERS LLC	0.27%	160.67K	27.73M	-6.83K	-4.08%
Jun 30, 2025	RICE HALL JAMES & ASSOCIATES, LLC	0.27%	160.11K	27.63M	-686	-0.43%
Jun 30, 2025	LOOMIS SAYLES & CO L P	0.25%	148.5K	25.63M	-26.42K	-15.10%
Jun 30, 2025	TRI LOCUM PARTNERS LP	0.25%	147.64K	25.48M	115.32K	+356.74%
Jun 30, 2025	ABRDN PLC	0.23%	139.61K	24.1M	-32.13K	-18.71%
Mar 31, 2025	RA CAPITAL MANAGEMENT, L.P.	17.13%	10.28M	1.6B	168.75K	+1.67%
Mar 31, 2025	SEI INVESTMENTS CO	0.43%	258.01K	40.21M	-5.57K	-2.11%
Mar 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	3.76%	2.26M	351.64M	-27.11K	-1.19%
Mar 31, 2025	CAPITAL INTERNATIONAL INVESTORS	4.79%	2.87M	448.07M	11.54K	+0.40%
Mar 31, 2025	FMR LLC	7.79%	4.67M	728.32M	-55.7K	-1.18%
Mar 31, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	5.09%	3.05M	475.97M	328.28K	+12.04%
Mar 31, 2025	RESOLUTE CAPITAL ASSET PARTNERS LLC	0.28%	167.5K	26.11M	53K	+46.29%
Mar 31, 2025	ABRDN PLC	0.29%	171.73K	26.77M	-15.45K	-8.25%
Mar 31, 2025	UBS GROUP AG	0.29%	173.84K	27.09M	-51.85K	-22.97%
Mar 31, 2025	LOOMIS SAYLES & CO L P	0.29%	174.91K	27.26M	-3.99K	-2.23%
Mar 31, 2025	TD ASSET MANAGEMENT INC	0.57%	343.39K	53.52M	3.74K	+1.10%
Mar 31, 2025	Q GLOBAL ADVISORS, LLC	0.41%	248.89K	38.79M	29.43K	+13.41%
Mar 31, 2025	WESTFIELD CAPITAL MANAGEMENT CO LP	9.13%	5.48M	854M	-48.98K	-0.89%
Mar 31, 2025	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.58%	346.02K	53.93M	47.02K	+15.73%
Mar 31, 2025	CAMBER CAPITAL MANAGEMENT LP	0.58%	350K	54.55M	-450K	-56.25%
Mar 31, 2025	ARTISAN PARTNERS LIMITED PARTNERSHIP	7.09%	4.26M	663.44M	-193.79K	-4.35%
Mar 31, 2025	JANUS HENDERSON GROUP PLC	7.48%	4.49M	693.95M	106.57K	+2.43%
Mar 31, 2025	FIL LTD	0.77%	462.37K	72.06M	-266.91K	-36.60%
Mar 31, 2025	POLAR CAPITAL HOLDINGS PLC	0.87%	525K	81.83M	225K	+75.00%
Mar 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.98%	587.76K	91.61M	-116.41K	-16.53%
Mar 31, 2025	AMERIPRISE FINANCIAL INC	1.13%	679.94K	105.98M	-22.62K	-3.22%
Mar 31, 2025	CITADEL ADVISORS LLC	1.87%	1.13M	175.37M	229.2K	+25.58%
Mar 31, 2025	MASSACHUSETTS FINANCIAL SERVICES CO /MA/	3.13%	1.88M	292.69M	10.37K	+0.56%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.98%	585.58K	91.27M	55.16K	+10.40%
Mar 31, 2025	BLACKROCK, INC.	0.86%	517.15K	80.6M	-136.13K	-20.84%
Mar 31, 2025	AMERICAN CENTURY COMPANIES INC	0.77%	462.17K	72.03M	54.88K	+13.47%
Mar 31, 2025	ALLIANCEBERNSTEIN L.P.	0.72%	432.1K	67.35M	-12.93K	-2.91%
Mar 31, 2025	GROUPAMA ASSET MANAGMENT	0.67%	400K	482.38K	0	0
Mar 31, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.55%	327.41K	51.03M	327.41K	+100.00%
Mar 31, 2025	ARS INVESTMENT PARTNERS, LLC	0.44%	265.16K	36.51M	-316	-0.12%
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	0.44%	264.87K	41.28M	-93.28K	-26.04%
Mar 31, 2025	ALLSPRING GLOBAL INVESTMENTS HOLDINGS, LLC	0.32%	189.61K	28.71M	36.88K	+24.14%
Mar 31, 2025	PFM HEALTH SCIENCES, LP	0.31%	186.92K	29.13M	134.52K	+256.76%
Mar 31, 2025	JPMORGAN CHASE & CO	0.31%	185.12K	28.85M	107.7K	+139.09%
Mar 31, 2025	RICE HALL JAMES & ASSOCIATES, LLC	0.27%	160.8K	25.06M	-3.09K	-1.89%
Mar 31, 2025	DUQUESNE FAMILY OFFICE LLC	0.26%	158.72K	24.74M	-106.32K	-40.11%
Mar 31, 2025	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	0.55%	330.15K	51.46M	13.57K	+4.29%
Mar 31, 2025	AVORO CAPITAL ADVISORS LLC	8.69%	5.22M	813.28M	114.95K	+2.25%
Mar 31, 2025		0.33%	195.52K	30.47M	-20.06K	-9.31%
Mar 31, 2025	SATURN V CAPITAL MANAGEMENT LLC	0.33%	199.26K	31.06M	287	+0.14%
Mar 31, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.34%	204.48K	31.87M	0	0
Mar 31, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	0.36%	216K	33.67M	-89K	-29.18%
Mar 31, 2025	WOODLINE PARTNERS LP	0.51%	304.81K	47.51M	-12.84K	-4.04%
Mar 31, 2025	INVESCO LTD.	2%	1.2M	186.79M	42.47K	+3.67%
Mar 31, 2025	MORGAN STANLEY	3.17%	1.9M	296.68M	1.08M	+130.52%
Mar 31, 2025	FRANKLIN RESOURCES INC	2.73%	1.64M	255.63M	283.7K	+20.92%
Mar 31, 2025	FINEPOINT CAPITAL LP	0.3%	179.87K	28.03M	-5K	-2.70%
Mar 31, 2025	SIREN, L.L.C.	0.48%	287.37K	44.79M	-9.96K	-3.35%
Mar 31, 2025	CANDRIAM S.C.A.	0.4%	242.76K	37.84M	-37.39K	-13.35%
Mar 31, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.95%	569.15K	88.71M	65.48K	+13.00%
Mar 31, 2024	DEUTSCHE BANK AG\	0.46%	261.03K	39.46M	-111.39K	-29.91%
Mar 31, 2024	ABRDN PLC	0.25%	138.79K	20.98M	0	0
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.27%	150.94K	22.82M	-62.23K	-29.19%
Mar 31, 2024	ALLSPRING GLOBAL INVESTMENTS HOLDINGS, LLC	0.33%	189.21K	28.6M	-13.96K	-6.87%
Mar 31, 2024	WOODLINE PARTNERS LP	0.35%	196.03K	29.63M	179.88K	+1,113.88%
Mar 31, 2024	NEW YORK STATE COMMON RETIREMENT FUND	0.35%	196.08K	29.64M	-8.47K	-4.14%
Mar 31, 2024	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.37%	209.51K	31.67M	65.51K	+45.49%
Mar 31, 2024	ARS INVESTMENT PARTNERS, LLC	0.45%	254.97K	38.54M	-27.78K	-9.82%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.47%	264.45K	39.98M	112.61K	+74.16%
Mar 31, 2024	PICTET ASSET MANAGEMENT HOLDING SA	0.48%	270.77K	40.93M	67.12K	+32.96%
Mar 31, 2024	D. E. SHAW & CO., INC.	0.6%	340.12K	51.42M	74.96K	+28.27%
Mar 31, 2024	SEI INVESTMENTS CO	0.61%	346.19K	52.33M	-15.64K	-4.32%
Mar 31, 2024	WELLINGTON MANAGEMENT GROUP LLP	4.85%	2.75M	415.09M	-502.42K	-15.47%
Mar 31, 2024	JANUS HENDERSON GROUP PLC	6.65%	3.77M	569.38M	-227.58K	-5.70%
Mar 31, 2024	TWO SIGMA INVESTMENTS, LP	0.37%	210.33K	31.79M	210.33K	+100.00%
Mar 31, 2024	SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC	0.4%	225.11K	34.03M	225.11K	+100.00%
Mar 31, 2024	TD ASSET MANAGEMENT INC	0.42%	236.87K	35.81M	-7.71K	-3.15%
Mar 31, 2024	AVORO CAPITAL ADVISORS LLC	7.01%	3.97M	599.64M	211.11K	+5.62%
Mar 31, 2024	WESTFIELD CAPITAL MANAGEMENT CO LP	7.2%	4.08M	616.05M	44.58K	+1.11%
Mar 31, 2024	FIRST TURN MANAGEMENT, LLC	0.27%	151.59K	22.92M	0	0
Mar 31, 2024	MORGAN STANLEY	0.27%	152.05K	22.99M	30.18K	+24.76%
Mar 31, 2024	RICE HALL JAMES & ASSOCIATES, LLC	0.29%	162.41K	24.55M	-6.47K	-3.83%
Mar 31, 2024	TWO SIGMA ADVISERS, LP	0.29%	163.4K	24.7M	163.4K	+100.00%
Mar 31, 2024	FINEPOINT CAPITAL LP	0.31%	175.67K	26.56M	11.9K	+7.27%
Mar 31, 2024	FRED ALGER MANAGEMENT, LLC	0.33%	186.12K	28.14M	-7.38K	-3.81%
Mar 31, 2024	Q GLOBAL ADVISORS, LLC	0.5%	285K	43.08M	0	0
Mar 31, 2024	ROCK SPRINGS CAPITAL MANAGEMENT LP	0.51%	290K	43.84M	0	0
Mar 31, 2024	AMERICAN CENTURY COMPANIES INC	0.54%	306.14K	46.28M	-1.6K	-0.52%
Mar 31, 2024	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.54%	307.5K	46.48M	234.16K	+319.31%
Mar 31, 2024	MILLENNIUM MANAGEMENT LLC	0.64%	362.06K	54.73M	339.67K	+1,516.99%
Mar 31, 2024	BLACKROCK INC.	0.72%	405.17K	61.25M	56.15K	+16.09%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.77%	437.09K	66.08M	14.24K	+3.37%
Mar 31, 2024	CITADEL ADVISORS LLC	0.81%	457.5K	69.16M	285.93K	+166.66%
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	0.84%	473.75K	71.62M	-115.18K	-19.56%
Mar 31, 2024	PARADIGM BIOCAPITAL ADVISORS LP	0.9%	507.95K	76.79M	156.25K	+44.43%
Mar 31, 2024	VESTAL POINT CAPITAL, LP	0.93%	525K	79.36M	-100K	-16.00%
Mar 31, 2024	TIMESSQUARE CAPITAL MANAGEMENT, LLC	1.02%	575.7K	87.03M	-217.25K	-27.40%
Mar 31, 2024	SPYGLASS CAPITAL MANAGEMENT LLC	1.08%	614.11K	92.83M	74.16K	+13.73%
Mar 31, 2024	BROWN ADVISORY INC	1.21%	684.07K	103.41M	178.13K	+35.21%
Mar 31, 2024	SOFINNOVA INVESTMENTS, INC.	1.33%	754.03K	113.99M	0	0
Mar 31, 2024	INVESCO LTD.	1.7%	964.66K	145.83M	56.75K	+6.25%
Mar 31, 2024	MASSACHUSETTS FINANCIAL SERVICES CO /MA/	2.86%	1.62M	244.57M	98.61K	+6.49%
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	3.15%	1.78M	269.37M	336.98K	+23.32%
Mar 31, 2024	FRANKLIN RESOURCES INC	3.5%	1.98M	299.6M	917.06K	+86.13%
Mar 31, 2024	CAPITAL INTERNATIONAL INVESTORS	3.87%	2.19M	331.26M	10.04K	+0.46%
Mar 31, 2024	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	4.54%	2.57M	388.34M	-1.42M	-35.61%
Mar 31, 2024	FMR LLC	8.72%	4.94M	746.55M	-175.91K	-3.44%
Mar 31, 2024	ARTISAN PARTNERS LIMITED PARTNERSHIP	10.02%	5.67M	857.43M	-77.29K	-1.34%
Mar 31, 2024	ACADIAN ASSET MANAGEMENT LLC	0.44%	250.49K	37.85M	234.45K	+1,461.09%
Mar 31, 2024	RA CAPITAL MANAGEMENT, L.P.	17.85%	10.11M	1.53B	1K	+0.01%
Mar 31, 2024	NICHOLAS INVESTMENT PARTNERS, LP	0.03%	17.98K	2.72M	13.72K	+321.47%
Mar 31, 2024	TREXQUANT INVESTMENT LP	0.04%	20.29K	3.07M	10.42K	+105.60%
Mar 31, 2024	HARBOR CAPITAL ADVISORS, INC.	0.04%	22.01K	3.33M	9.92K	+82.09%
Mar 31, 2024	JEFFERIES FINANCIAL GROUP INC.	0.04%	24.15K	3.65M	-3.85K	-13.75%
Mar 31, 2024	HENRY JAMES INTERNATIONAL MANAGEMENT INC.	0.04%	24.52K	3.71M	26	+0.11%
Mar 31, 2024	CITIGROUP INC	0.04%	19.98K	3.02M	952	+5.00%
Mar 31, 2024	UBS GROUP AG	0.05%	27.76K	4.2M	-172	-0.62%
Mar 31, 2024	JPMORGAN CHASE & CO	0.05%	28.01K	4.23M	-33.86K	-54.73%
Mar 31, 2024	DEKABANK DEUTSCHE GIROZENTRALE	0.05%	30K	4.44M	0	0
Mar 31, 2024	MATISSE CAPITAL	0.06%	35.54K	5.37M	905	+2.61%
Mar 31, 2024	RESOLUTE CAPITAL ASSET PARTNERS LLC	0.08%	47K	7.11M	10.6K	+29.12%
Mar 31, 2024	ATIKA CAPITAL MANAGEMENT LLC	0.09%	48.5K	7.33M	48.5K	+100.00%
Mar 31, 2024	GRAY FOUNDATION	0.09%	51.7K	7.82M	0	0
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.1%	54.53K	8.24M	31.74K	+139.28%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	0.1%	56.1K	8.48M	1.01K	+1.84%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.11%	60K	9.07M	60K	+100.00%
Mar 31, 2024	ENSIGN PEAK ADVISORS, INC	0.12%	67.54K	10.21M	0	0
Mar 31, 2024	BNP PARIBAS ARBITRAGE, SNC	0.13%	75.54K	11.42M	73.8K	+4,231.42%
Mar 31, 2024	BAILLIE GIFFORD & CO	0.14%	81.21K	12.28M	-464	-0.57%
Mar 31, 2024	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	0.15%	86.2K	13.03M	86.2K	+100.00%
Mar 31, 2024	CANDRIAM S.C.A.	0.18%	99.38K	15.02M	0	0
Mar 31, 2024	THRIVENT FINANCIAL FOR LUTHERANS	0.2%	114.4K	17.29M	1.14K	+1.00%
Mar 31, 2024	VICTORY CAPITAL MANAGEMENT INC	0.24%	134.56K	20.34M	134.56K	+100.00%
Dec 31, 2023	BLACKROCK INC.	0.62%	349.02K	43.96M	15.46K	+4.63%
Dec 31, 2023	MORGAN STANLEY	0.22%	121.88K	15.35M	45.19K	+58.94%
Dec 31, 2023	DAFNA CAPITAL MANAGEMENT LLC	0.22%	123.47K	15.55M	-12.74K	-9.35%
Dec 31, 2023	SCHONFELD STRATEGIC ADVISORS LLC	0.22%	124.9K	15.73M	86K	+221.08%
Dec 31, 2023	SATURN V CAPITAL MANAGEMENT LLC	0.23%	131.76K	16.6M	19.29K	+17.15%
Dec 31, 2023	PERCEPTIVE ADVISORS LLC	0.23%	132.18K	16.65M	132.18K	+100.00%
Dec 31, 2023	ABRDN PLC	0.25%	138.79K	17.48M	138.79K	+100.00%
Dec 31, 2023	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.26%	144K	18.14M	-382.37K	-72.64%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.27%	151.84K	19.12M	-95.69K	-38.66%
Dec 31, 2023	FINEPOINT CAPITAL LP	0.29%	163.77K	20.63M	0	0
Dec 31, 2023	CAMBER CAPITAL MANAGEMENT LP	0.29%	165K	20.78M	165K	+100.00%
Dec 31, 2023	RICE HALL JAMES & ASSOCIATES, LLC	0.3%	168.88K	21.27M	-904	-0.53%
Dec 31, 2023	CITADEL ADVISORS LLC	0.3%	171.57K	21.61M	171.32K	+69,081.85%
Dec 31, 2023	EVENTIDE ASSET MANAGEMENT, LLC	0.32%	180.86K	22.78M	-394.58K	-68.57%
Dec 31, 2023	FRED ALGER MANAGEMENT, LLC	0.34%	193.5K	24.37M	-76.5K	-28.33%
Dec 31, 2023	ALLSPRING GLOBAL INVESTMENTS HOLDINGS, LLC	0.36%	203.17K	25.59M	-9.82K	-4.61%
Dec 31, 2023	NEW YORK STATE COMMON RETIREMENT FUND	0.36%	204.55K	25.76M	-152	-0.07%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.38%	213.17K	26.85M	-19.59K	-8.42%
Dec 31, 2023	TD ASSET MANAGEMENT INC	0.43%	244.58K	30.8M	-22.78K	-8.52%
Dec 31, 2023	D. E. SHAW & CO., INC.	0.47%	265.16K	33.4M	44.6K	+20.22%
Dec 31, 2023	ARS INVESTMENT PARTNERS, LLC	0.5%	282.74K	35.61M	-3.17K	-1.11%
Dec 31, 2023	Q GLOBAL ADVISORS, LLC	0.51%	285K	35.9M	0	0
Dec 31, 2023	ROCK SPRINGS CAPITAL MANAGEMENT LP	0.52%	290K	36.53M	-135.5K	-31.84%
Dec 31, 2023	AMERICAN CENTURY COMPANIES INC	0.55%	307.74K	38.76M	-21.54K	-6.54%
Dec 31, 2023	PARADIGM BIOCAPITAL ADVISORS LP	0.62%	351.7K	44.3M	351.7K	+100.00%
Dec 31, 2023	SEI INVESTMENTS CO	0.64%	361.83K	45.57M	-34.61K	-8.73%
Dec 31, 2023	DEUTSCHE BANK AG\	0.66%	372.41K	46.91M	11.39K	+3.15%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.75%	422.85K	53.26M	12.88K	+3.14%
Dec 31, 2023	BROWN ADVISORY INC	0.9%	505.95K	63.72M	-4.16K	-0.82%
Dec 31, 2023	SPYGLASS CAPITAL MANAGEMENT LLC	0.96%	539.95K	68.01M	-74.67K	-12.15%
Dec 31, 2023		0.27%	151.59K	19.09M	151.59K	+100.00%
Dec 31, 2023	ALLIANCEBERNSTEIN L.P.	1.05%	588.94K	74.18M	-13.94K	-2.31%
Dec 31, 2023	PUTNAM INVESTMENTS LLC	1.29%	725.65K	91.4M	-46.71K	-6.05%
Dec 31, 2023	SOFINNOVA INVESTMENTS, INC.	1.34%	754.03K	94.97M	0	0
Dec 31, 2023	TIMESSQUARE CAPITAL MANAGEMENT, LLC	1.41%	792.95K	99.87M	-49.86K	-5.92%
Dec 31, 2023	INVESCO LTD.	1.61%	907.91K	114.35M	235.79K	+35.08%
Dec 31, 2023	FRANKLIN RESOURCES INC	1.89%	1.06M	134.11M	-148.48K	-12.24%
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	2.57%	1.44M	181.99M	-192.9K	-11.78%
Dec 31, 2023	MASSACHUSETTS FINANCIAL SERVICES CO /MA/	2.7%	1.52M	191.35M	254.75K	+20.15%
Dec 31, 2023	CAPITAL INTERNATIONAL INVESTORS	3.88%	2.18M	274.73M	12.83K	+0.59%
Dec 31, 2023	WELLINGTON MANAGEMENT GROUP LLP	5.77%	3.25M	409.12M	3.25M	+100.00%
Dec 31, 2023	AVORO CAPITAL ADVISORS LLC	6.67%	3.76M	473.01M	85.56K	+2.33%
Dec 31, 2023	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	7.09%	3.99M	502.52M	5.33K	+0.13%
Dec 31, 2023	JANUS HENDERSON GROUP PLC	7.1%	3.99M	503.1M	140.25K	+3.64%
Dec 31, 2023	WESTFIELD CAPITAL MANAGEMENT CO LP	7.16%	4.03M	507.66M	228.46K	+6.01%
Dec 31, 2023	FMR LLC	9.09%	5.11M	644.15M	-21.91K	-0.43%
Dec 31, 2023	ARTISAN PARTNERS LIMITED PARTNERSHIP	10.21%	5.75M	724.12M	-246.18K	-4.11%
Dec 31, 2023	RA CAPITAL MANAGEMENT, L.P.	17.96%	10.11M	1.27B	-612.16K	-5.71%
Sep 30, 2023	GOLDMAN SACHS GROUP INC	0.73%	409.97K	-	12.88K	+3.24%
Sep 30, 2023	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.05%	25.57K	-	-19.72K	-43.53%
Sep 30, 2023	CAPTION MANAGEMENT, LLC	0.05%	26K	-	-117.2K	-81.84%
Sep 30, 2023	MATISSE CAPITAL	0.05%	26.26K	-	-5.7K	-17.82%
Sep 30, 2023	DEKABANK DEUTSCHE GIROZENTRALE	0.05%	30K	-	0	0
Sep 30, 2023	RESOLUTE CAPITAL ASSET PARTNERS LLC	0.07%	37.5K	-	0	0
Sep 30, 2023	SCHONFELD STRATEGIC ADVISORS LLC	0.07%	38.9K	-	7.7K	+24.68%
Sep 30, 2023	UBS GROUP AG	0.08%	43.23K	-	-556	-1.27%
Sep 30, 2023	CITIGROUP INC	0.09%	51.6K	-	26.6K	+106.40%
Sep 30, 2023	GEODE CAPITAL MANAGEMENT, LLC	0.1%	54.56K	-	990	+1.85%
Sep 30, 2023	AMERIPRISE FINANCIAL INC	0.11%	60.58K	-	-8.04K	-11.72%
Sep 30, 2023	ENSIGN PEAK ADVISORS, INC	0.12%	67.54K	-	-149	-0.22%
Sep 30, 2023	MORGAN STANLEY	0.14%	76.68K	-	-7.42K	-8.82%
Sep 30, 2023	BAILLIE GIFFORD & CO	0.15%	86.32K	-	-4.18K	-4.62%
Sep 30, 2023	BALYASNY ASSET MANAGEMENT L.P.	0.17%	94.87K	-	94.87K	+100.00%
Sep 30, 2023	SATURN V CAPITAL MANAGEMENT LLC	0.2%	112.47K	-	34.03K	+43.38%
Sep 30, 2023	DAFNA CAPITAL MANAGEMENT LLC	0.24%	136.21K	-	1K	+0.74%
Sep 30, 2023	CANDRIAM S.C.A.	0.25%	139.38K	-	-9K	-6.07%
Sep 30, 2023	JENNISON ASSOCIATES LLC	0.28%	159.43K	-	37.36K	+30.61%
Sep 30, 2023	FINEPOINT CAPITAL LP	0.29%	163.77K	-	24K	+17.17%
Sep 30, 2023	RICE HALL JAMES & ASSOCIATES, LLC	0.3%	169.79K	-	-3.68K	-2.12%
Sep 30, 2023	NICHOLAS INVESTMENT PARTNERS, LP	0.3%	170.61K	-	0	0
Sep 30, 2023		0.3%	170.87K	-	170.87K	+100.00%
Sep 30, 2023	NEW YORK STATE COMMON RETIREMENT FUND	0.36%	204.7K	-	-3	0.00%
Sep 30, 2023	ARTISAN PARTNERS LIMITED PARTNERSHIP	10.66%	6M	-	-227.04K	-3.65%
Sep 30, 2023	ROCK SPRINGS CAPITAL MANAGEMENT LP	0.76%	425.5K	-	0	0
Sep 30, 2023	ALLSPRING GLOBAL INVESTMENTS HOLDINGS, LLC	0.38%	213K	-	-11.52K	-5.13%
Sep 30, 2023	D. E. SHAW & CO., INC.	0.39%	220.55K	-	88.47K	+66.98%
Sep 30, 2023	BANK OF NEW YORK MELLON CORP	0.41%	232.76K	-	-83.23K	-26.34%
Sep 30, 2023	TD ASSET MANAGEMENT INC	0.48%	267.36K	-	12.61K	+4.95%
Sep 30, 2023	FRED ALGER MANAGEMENT, LLC	0.48%	270.01K	-	-81.01K	-23.08%
Sep 30, 2023	Q GLOBAL ADVISORS, LLC	0.51%	285K	-	90K	+46.15%
Sep 30, 2023	ARS INVESTMENT PARTNERS, LLC	0.51%	285.92K	-	-3.94K	-1.36%
Sep 30, 2023	FMR LLC	9.14%	5.14M	-	-4.52K	-0.09%
Sep 30, 2023	WESTFIELD CAPITAL MANAGEMENT CO LP	6.76%	3.8M	-	170.47K	+4.69%
Sep 30, 2023	AVORO CAPITAL ADVISORS LLC	6.53%	3.67M	-	89.45K	+2.50%
Sep 30, 2023	CAPITAL INTERNATIONAL INVESTORS	3.86%	2.17M	-	173.17K	+8.68%
Sep 30, 2023	MASSACHUSETTS FINANCIAL SERVICES CO /MA/	2.25%	1.26M	-	176.95K	+16.27%
Sep 30, 2023	FRANKLIN RESOURCES INC	2.16%	1.21M	-	-40	0.00%
Sep 30, 2023	RA CAPITAL MANAGEMENT, L.P.	19.07%	10.72M	-	-505.8K	-4.51%
Sep 30, 2023	TIMESSQUARE CAPITAL MANAGEMENT, LLC	1.5%	842.8K	-	75.37K	+9.82%
Sep 30, 2023	PUTNAM INVESTMENTS LLC	1.37%	772.36K	-	-127.47K	-14.17%
Sep 30, 2023	INVESCO LTD.	1.2%	672.13K	-	57.41K	+9.34%
Sep 30, 2023	ALLIANCEBERNSTEIN L.P.	1.07%	602.87K	-	24.49K	+4.23%
Sep 30, 2023	EVENTIDE ASSET MANAGEMENT, LLC	1.02%	575.44K	-	6	0.00%
Sep 30, 2023	BROWN ADVISORY INC	0.91%	510.11K	-	13.23K	+2.66%
Sep 30, 2023	AMERICAN CENTURY COMPANIES INC	0.59%	329.27K	-	-33.09K	-9.13%
Sep 30, 2023	BLACKROCK INC.	0.59%	333.57K	-	-27.52K	-7.62%
Sep 30, 2023	DEUTSCHE BANK AG\	0.64%	361.03K	-	0	0

Insiders

Among the ASND insiders holding of 0.76% of the stake in company, SMITH SCOTT THOMAS, EVP & Chief Financial Officer, holds the largest shares of 4.37K. BIENAIME JEAN JACQUES, director, is the second largest ASND insider with ownership of 600 shares. JENSEN FLEMMING STEEN, See Remarks, stands third with possession of 0 shares of that stake.

Insiders	Designation	Shares Held
SMITH SCOTT THOMAS	EVP & Chief Financial Officer	4.37K
BIENAIME JEAN JACQUES	director	600
JENSEN FLEMMING STEEN	See Remarks	0

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Jun 02, 2026	SMITH SCOTT THOMAS	PURCHASE	219.00	100	21.9K	4.37K
May 29, 2026	BIENAIME JEAN JACQUES	PURCHASE	223.76	200	44.75K	600
May 29, 2026	SMITH SCOTT THOMAS	PURCHASE	223.32	250	55.83K	4.27K
May 26, 2026	BIENAIME JEAN JACQUES	PURCHASE	236.24	200	47.25K	200
May 11, 2026	JENSEN FLEMMING STEEN	SALE	238.49	19.46K	4.64M	0

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE7504

SALES19.46K1

NET SHARES-18.71K3

SHARES HELD9.43K5

% NET SHARES-298.33%-40%

Frequently Asked Questions