How many institutions own ANAB stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own ANAB shares is 232, representing 114.44% of the company's common stock.

Who are the major shareholders selling AnaptysBio, Inc. stock?

PALO ALTO INVESTORS LP, in the last quarter, reduced its stake in ANAB by -17.14% restricting it's holding to 673.52 thousand shares of worth nearly $20.62M. VANGUARD GROUP INC also lessened -3.94% of the ANAB shares from its portfolio, reducing its holding to 1.48 million shares of worth $45.23M. BANK OF NEW YORK MELLON CORP also shunned ANAB shares holding by -3.71% last quarter which brought its holding to 57.03 thousand shares worth $1.75M.

Investors who are buying ANAB stock?

As per its latest 13F filing, JANE STREET GROUP, LLC increased its stake in ANAB by 305.46% in the last quarter. The institutional holder raised its holding to 181.11 thousand shares having worth more than $5.55M. ASSENAGON ASSET MANAGEMENT S.A. also added 4,852.73% more shares of ANAB to its portfolio, raising its holding to 839.93 thousand shares of worth $25.72M. MILLENNIUM MANAGEMENT LLC also increased its ANAB shares holding by 646.4% which brought its holding to 1.52 million shares worth $46.52M.

ANAB's major insiders: who are they?

The insider with the most stakes in ANAB is EcoR1 Capital, LLC , at the company. Additionally, ANAB stock is highly held by NODELMAN OLEG and 10 percent owner Novo A/S among others.

Did an insider recently sell ANAB stock?

Company executives, directors, and other insiders own 5.76% percent of AnaptysBio, Inc.'s stock. Within the last six months, there have been 18 transaction(s) in which ANAB insiders have sold stock, totaling 101.18K shares. Insiders that have sold shares include LOUMEAU ERIC J, MULROY DENNIS, and FAGA DANIEL.

Which insider recently purchased ANAB stock?

There have been 0 transaction(s) during the past 6-months in which AnaptysBio, Inc. insiders have bought stock, totalling 0 shares

How much of ANAB does insiders own?

Around 1.16M AnaptysBio, Inc. shares are held by insiders, which represents about 5.76% of ANAB stock.

Who is the insider with the largest stake?

ANAB , EcoR1 Capital, LLC holds the largest portfolio of the company's shares. ANAB shares owned by EcoR1 total nearly 7.88 million.

Which institution holds the most shares in ANAB?

JANE STREET GROUP, LLC is the largest institutional owner in ANAB which holds 181.11 thousand shares worth $5.55M or 0.63% of the total ANAB shares outstanding followed by PALO ALTO INVESTORS LP with ownership of 673.52 thousand shares representing 2.34% of the ANAB ownership. SANOFI is the third largest stakeholder with 821.92 thousand shares or 2.85% of the ownership worth more than $25.17M.

Is AnaptysBio, Inc. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the ANAB is concerned, it is a stock which is optionable.

Is there a short position on ANAB's shares?

Number of ANAB shares short is 5.64M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding ANAB shares are there?

As of today, 27.69M shares of ANAB are outstanding.

Is there many float in ANAB stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, ANAB has 14.42M shares in float.

ANAB short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for ANAB is 10.19.

AnaptysBio (ANAB) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares20.38

Short Percent Of Float38.69

Shares Outstanding27.69M

Shares Float14.42M

Shares Short5.64M

Short Ratio10.19

38.69%

Short % of Float

20.38%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

5.76% Percentage of Shares held by All Insiders

114.44% Percentage of Shares held by All Institutions

121.43% Percentage of Float held by Institutions

232

Number of Institutions Holding Shares

Institutional Ownership

About 114.44% of ANAB shares are held by financial institutions. JANE STREET GROUP, LLC is the top corporate investor, holding 181.11K shares valued at $5.55M. A 0.63% stake in AnaptysBio, Inc. is owned by the company. PALO ALTO INVESTORS LP owns 673.52K shares valued at $20.62M, which translates its holding of 2.34% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Sep 30, 2025	JANE STREET GROUP, LLC	0.63%	181.11K	5.55M	136.44K	+305.46%
Sep 30, 2025	PALO ALTO INVESTORS LP	2.34%	673.52K	20.62M	-139.3K	-17.14%
Sep 30, 2025	SANOFI	2.85%	821.92K	25.17M	0	0
Sep 30, 2025	ASSENAGON ASSET MANAGEMENT S.A.	2.92%	839.93K	25.72M	822.98K	+4,852.73%
Sep 30, 2025	VANGUARD GROUP INC	5.13%	1.48M	45.23M	-60.56K	-3.94%
Sep 30, 2025	MILLENNIUM MANAGEMENT LLC	5.27%	1.52M	46.52M	1.32M	+646.40%
Sep 30, 2025	WALLEYE CAPITAL LLC	0.2%	56.42K	1.73M	56.42K	+100.00%
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.2%	57.03K	1.75M	-2.2K	-3.71%
Sep 30, 2025	FISHER ASSET MANAGEMENT, LLC	0.2%	58.88K	1.8M	-21	-0.04%
Sep 30, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.21%	60.6K	1.86M	60.6K	+100.00%
Sep 30, 2025	BARCLAYS PLC	0.22%	63.45K	1.94M	-36.55K	-36.55%
Sep 30, 2025	FIRST LIGHT ASSET MANAGEMENT, LLC	3.44%	990.16K	30.32M	-2.55M	-72.03%
Sep 30, 2025	TANG CAPITAL MANAGEMENT LLC	4.63%	1.33M	40.84M	2.76K	+0.21%
Sep 30, 2025	MORGAN STANLEY	5.4%	1.56M	47.65M	-313.58K	-16.77%
Sep 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	7.86%	2.27M	69.37M	-209.35K	-8.46%
Sep 30, 2025	ECOR1 CAPITAL, LLC	27.35%	7.88M	241.29M	0	0
Sep 30, 2025	GOLDMAN SACHS GROUP INC	1.14%	329.82K	10.1M	49.99K	+17.86%
Sep 30, 2025	PANAGORA ASSET MANAGEMENT INC	0.22%	63.86K	1.96M	30.49K	+91.37%
Sep 30, 2025	UBS GROUP AG	0.26%	75.26K	2.3M	-1.2M	-94.09%
Sep 30, 2025	JUMP FINANCIAL, LLC	0.28%	82.08K	2.51M	82.08K	+100.00%
Sep 30, 2025	HIGHMARK WEALTH MANAGEMENT LLC	0.47%	135.05K	4.42M	-10.5K	-7.21%
Sep 30, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	2.17%	626.04K	19.17M	305K	+95.00%
Sep 30, 2025	BLACKROCK, INC.	5.98%	1.72M	52.74M	-64.61K	-3.62%
Sep 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.5%	144.6K	4.43M	-44.72K	-23.62%
Sep 30, 2025	IKARIAN CAPITAL, LLC	0.56%	161.1K	4.93M	161.1K	+100.00%
Sep 30, 2025	TWO SIGMA INVESTMENTS, LP	0.89%	256.42K	7.85M	25.05K	+10.83%
Sep 30, 2025	GRANAHAN INVESTMENT MANAGEMENT, LLC	0.51%	147.77K	4.52M	16.12K	+12.24%
Sep 30, 2025	SKANDINAVISKA ENSKILDA BANKEN AB (PUBL)	0.5%	145.19K	4.45M	111.67K	+333.11%
Sep 30, 2025	SECTORAL ASSET MANAGEMENT INC	0.68%	194.49K	5.96M	110.59K	+131.81%
Sep 30, 2025	ENSIGN PEAK ADVISORS, INC	0.75%	215.45K	6.6M	0	0
Sep 30, 2025	SOFINNOVA INVESTMENTS, INC.	0.88%	254.27K	7.79M	-778.09K	-75.37%
Sep 30, 2025	TWO SIGMA ADVISERS, LP	1.3%	373.7K	11.44M	83.3K	+28.68%
Sep 30, 2025	JACOBS LEVY EQUITY MANAGEMENT, INC	1.31%	378.45K	11.59M	10.01K	+2.72%
Sep 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.04%	299.31K	9.17M	-373.86K	-55.54%
Sep 30, 2025	ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	1.29%	370.46K	11.34M	219.65K	+145.65%
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.43%	123.3K	3.78M	-139.79K	-53.13%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.44%	127.24K	3.9M	-949.56K	-88.18%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.72%	206.44K	6.32M	49.31K	+31.38%
Sep 30, 2025	NUVEEN, LLC	1.18%	339.27K	10.39M	15.74K	+4.86%
Sep 30, 2025	D. E. SHAW & CO., INC.	1.21%	349.36K	10.7M	237.01K	+210.96%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.64%	473.63K	14.5M	10.27K	+2.22%
Sep 30, 2025	STATE STREET CORP	3.03%	873.43K	26.74M	52.4K	+6.38%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.37%	105.66K	3.24M	101.96K	+2,756.53%
Sep 30, 2025	NORTHERN TRUST CORP	0.68%	195.56K	5.99M	-700	-0.36%
Sep 30, 2025	VICTORY CAPITAL MANAGEMENT INC	0.71%	204.06K	6.25M	-328.03K	-61.65%
Sep 30, 2025	WOODLINE PARTNERS LP	1.74%	501.02K	15.34M	0	0
Sep 30, 2025	683 CAPITAL MANAGEMENT, LLC	1.9%	547K	16.75M	47K	+9.40%
Sep 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.04%	10.59K	324.14K	2.66K	+33.59%
Sep 30, 2025	TEMA ETFS LLC	0.04%	10.98K	336.06K	-429	-3.76%
Sep 30, 2025	NEOS INVESTMENT MANAGEMENT LLC	0.04%	10.98K	336.06K	-429	-3.76%
Sep 30, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.04%	11.93K	365.24K	11.93K	+100.00%
Sep 30, 2025	DEUTSCHE BANK AG\	0.04%	12.68K	388.29K	0	0
Sep 30, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.05%	12.96K	396.87K	-60.04K	-82.25%
Sep 30, 2025	ALPS ADVISORS INC	0.05%	13.34K	408.32K	-2.53K	-15.94%
Sep 30, 2025	BRINKER CAPITAL INVESTMENTS, LLC	0.05%	13.74K	420.69K	13.74K	+100.00%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0.05%	13.74K	420.81K	-19.59K	-58.76%
Sep 30, 2025	JPMORGAN CHASE & CO	0.05%	14.85K	454.77K	-232.77K	-94.00%
Sep 30, 2025	LOS ANGELES CAPITAL MANAGEMENT LLC	0.05%	14.88K	455.5K	-151	-1.00%
Sep 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.23%	66.73K	2.04M	-13.48K	-16.81%
Sep 30, 2025	SQUAREPOINT OPS LLC	0.24%	68.01K	2.08M	-41.37K	-37.82%
Sep 30, 2025	SEI INVESTMENTS CO	0.05%	14.92K	456.88K	14.92K	+100.00%
Sep 30, 2025	CRESSET ASSET MANAGEMENT, LLC	0.06%	16.89K	517.08K	3.72K	+28.27%
Sep 30, 2025	CAMPBELL & CO INVESTMENT ADVISER LLC	0.06%	18.28K	559.76K	18.28K	+100.00%
Sep 30, 2025	LEGAL & GENERAL GROUP PLC	0.07%	19.5K	597.21K	0	0
Sep 30, 2025	SWISS NATIONAL BANK	0.1%	28.4K	869.61K	2K	+7.58%
Sep 30, 2025	RHUMBLINE ADVISERS	0.1%	29.24K	895.44K	-1.46K	-4.76%
Sep 30, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.1%	30.09K	921.2K	3.26K	+12.14%
Sep 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0.12%	34.03K	1.04M	10.24K	+43.05%
Sep 30, 2025	GSA CAPITAL PARTNERS LLP	0.13%	37.27K	1.14M	-32.53K	-46.60%
Sep 30, 2025	BLEAKLEY FINANCIAL GROUP, LLC	0.14%	39.98K	1.22M	2.43K	+6.47%
Sep 30, 2025	INVESCO LTD.	0.15%	42.38K	1.3M	-40.79K	-49.05%
Sep 30, 2025	FRANKLIN RESOURCES INC	0.16%	47.33K	11.6M	-307.18K	-86.65%
Sep 30, 2025	DCF ADVISERS, LLC	0.17%	48K	1.47M	0	0
Sep 30, 2025	MOODY ALDRICH PARTNERS LLC	0.17%	49.88K	1.53M	-10.21K	-16.99%
Sep 30, 2025	FMR LLC	0.18%	53.16K	1.63M	-18.96K	-26.29%
Sep 30, 2025	MARSHALL WACE, LLP	0.19%	54.42K	1.67M	54.42K	+100.00%
Sep 30, 2025	ALGERT GLOBAL LLC	0.29%	83.77K	2.57M	83.77K	+100.00%
Sep 30, 2025	MACQUARIE GROUP LTD	0.33%	93.73K	2.87M	0	0
Sep 30, 2025	TREXQUANT INVESTMENT LP	0.39%	111.78K	3.42M	-87.46K	-43.90%
Sep 30, 2025	FEDERATED HERMES, INC.	0.67%	193.33K	5.92M	185.05K	+2,236.56%
Sep 30, 2025	CITIGROUP INC	0.24%	70.53K	2.16M	-975.95K	-93.26%
Jun 30, 2025	UBS GROUP AG	4.42%	1.27M	28.25M	782.23K	+159.55%
Jun 30, 2025	VANGUARD GROUP INC	5.34%	1.54M	34.13M	20.23K	+1.33%
Jun 30, 2025	FISHER ASSET MANAGEMENT, LLC	0.2%	58.9K	1.31M	21	+0.04%
Jun 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.04%	10.8K	239.65K	10.8K	+100.00%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	3.74%	1.08M	23.9M	-67.16K	-5.87%
Jun 30, 2025	SQUAREPOINT OPS LLC	0.38%	109.39K	2.43M	109.39K	+100.00%
Jun 30, 2025	CAMBER CAPITAL MANAGEMENT LP	0.43%	125K	2.78M	-625K	-83.33%
Jun 30, 2025	GRANAHAN INVESTMENT MANAGEMENT, LLC	0.46%	131.66K	2.92M	-14.84K	-10.13%
Jun 30, 2025	HIGHMARK WEALTH MANAGEMENT LLC	0.51%	145.55K	3.23M	53.55K	+58.21%
Jun 30, 2025	ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	0.52%	150.81K	3.35M	150.81K	+100.00%
Jun 30, 2025	SANOFI	2.85%	821.92K	18.25M	0	0
Jun 30, 2025	TANG CAPITAL MANAGEMENT LLC	4.62%	1.33M	29.55M	-214.27K	-13.87%
Jun 30, 2025	BLACKROCK, INC.	6.2%	1.79M	39.67M	-389.66K	-17.90%
Jun 30, 2025	MOODY ALDRICH PARTNERS LLC	0.21%	60.09K	1.33M	-23.13K	-27.79%
Jun 30, 2025	AQUATIC CAPITAL MANAGEMENT LLC	0.23%	65.81K	1.46M	65.81K	+100.00%
Jun 30, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.25%	73.01K	1.62M	-23.97K	-24.72%
Jun 30, 2025	NUVEEN, LLC	1.12%	323.53K	7.18M	267.52K	+477.62%
Jun 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.28%	80.21K	1.78M	4.19K	+5.51%
Jun 30, 2025	INVESCO LTD.	0.29%	83.17K	1.85M	61.84K	+289.83%
Jun 30, 2025	SECTORAL ASSET MANAGEMENT INC	0.29%	83.9K	1.86M	83.9K	+100.00%
Jun 30, 2025	BALYASNY ASSET MANAGEMENT L.P.	0.32%	92.85K	2.06M	60.78K	+189.49%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.34%	97.1K	2.16M	-40K	-29.18%
Jun 30, 2025	GSA CAPITAL PARTNERS LLP	0.24%	69.8K	1.55M	69.8K	+100.00%
Jun 30, 2025	FMR LLC	0.25%	72.12K	1.6B	-1.83M	-96.21%
Jun 30, 2025	TWO SIGMA INVESTMENTS, LP	0.8%	231.37K	5.14M	-34.49K	-12.97%
Jun 30, 2025	STATE STREET CORP	2.85%	821.03K	18.23M	-39.69K	-4.61%
Jun 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.91%	263.09K	5.84M	-75.61K	-22.32%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.97%	279.84K	6.21M	-742	-0.26%
Jun 30, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	1.11%	321.04K	7.13M	218.99K	+214.58%
Jun 30, 2025		1.12%	323.53K	7.18M	267.52K	+477.62%
Jun 30, 2025	FRANKLIN RESOURCES INC	1.23%	354.51K	7.87M	117	+0.03%
Jun 30, 2025	JACOBS LEVY EQUITY MANAGEMENT, INC	1.28%	368.45K	8.18M	351.96K	+2,134.77%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.61%	463.36K	10.29M	-27.81K	-5.66%
Jun 30, 2025	683 CAPITAL MANAGEMENT, LLC	1.74%	500K	11.1M	304.37K	+155.59%
Jun 30, 2025	WOODLINE PARTNERS LP	1.74%	501.02K	11.12M	-290K	-36.66%
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	2.34%	673.17K	14.95M	-241.91K	-26.44%
Jun 30, 2025	PALO ALTO INVESTORS LP	2.82%	812.82K	18.04M	-207.89K	-20.37%
Jun 30, 2025	MORGAN STANLEY	6.49%	1.87M	41.51M	1.37M	+270.53%
Jun 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	8.59%	2.47M	54.94M	106.5K	+4.50%
Jun 30, 2025	SOFINNOVA INVESTMENTS, INC.	3.58%	1.03M	22.92M	-127.67K	-11.01%
Jun 30, 2025	FIRST LIGHT ASSET MANAGEMENT, LLC	12.29%	3.54M	78.58M	-1.09M	-23.61%
Jun 30, 2025	ECOR1 CAPITAL, LLC	27.35%	7.88M	174.94M	0	0
Jun 30, 2025	CORTON CAPITAL INC.	0.04%	12K	266.49K	1.31K	+12.20%
Jun 30, 2025	CRESSET ASSET MANAGEMENT, LLC	0.05%	13.17K	292.26K	-1.45K	-9.91%
Jun 30, 2025	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0.05%	14.22K	315.62M	-373	-2.56%
Jun 30, 2025	EXOME ASSET MANAGEMENT LLC	0.05%	15K	333K	-101.62K	-87.14%
Jun 30, 2025	LOS ANGELES CAPITAL MANAGEMENT LLC	0.05%	15.03K	333.6K	15.03K	+100.00%
Jun 30, 2025	NEBULA RESEARCH & DEVELOPMENT LLC	0.05%	15.53K	344.83K	28	+0.18%
Jun 30, 2025	MACQUARIE GROUP LTD	0.33%	93.73K	2.08M	0	0
Jun 30, 2025	BARCLAYS PLC	0.35%	100K	2.22M	43.78K	+77.87%
Jun 30, 2025	D. E. SHAW & CO., INC.	0.39%	112.35K	2.49M	-17.31K	-13.35%
Jun 30, 2025	CITADEL ADVISORS LLC	0.41%	118.29K	2.63M	-254.28K	-68.25%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.55%	157.14K	3.49M	3.78K	+2.46%
Jun 30, 2025	NORTHERN TRUST CORP	0.68%	196.26K	4.36M	-16.62K	-7.81%
Jun 30, 2025	ENSIGN PEAK ADVISORS, INC	0.75%	215.45K	4.78M	0	0
Jun 30, 2025	JPMORGAN CHASE & CO	0.86%	247.63K	5.5M	233.33K	+1,631.64%
Jun 30, 2025	IKARIAN CAPITAL, LLC	0.05%	15.66K	347.7K	15.66K	+100.00%
Jun 30, 2025	ALPS ADVISORS INC	0.06%	15.86K	352.16K	-7.26K	-31.41%
Jun 30, 2025	TREXQUANT INVESTMENT LP	0.69%	199.24K	4.42M	45.68K	+29.75%
Jun 30, 2025	MILLENNIUM MANAGEMENT LLC	0.71%	203.54K	4.52M	185.74K	+1,043.04%
Jun 30, 2025	TWO SIGMA ADVISERS, LP	1.01%	290.4K	6.45M	22.3K	+8.32%
Jun 30, 2025	VICTORY CAPITAL MANAGEMENT INC	1.85%	532.09K	11.81M	125.66K	+30.92%
Jun 30, 2025	CITIGROUP INC	3.63%	1.05M	23.23M	-24.76K	-2.31%
Jun 30, 2025	ASSENAGON ASSET MANAGEMENT S.A.	0.06%	16.96K	376.49K	-225.53K	-93.01%
Jun 30, 2025	BREVAN HOWARD CAPITAL MANAGEMENT LP	0.08%	22.95K	509.56K	8.76K	+61.73%
Jun 30, 2025	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.08%	23.76K	527K	1.81K	+8.26%
Jun 30, 2025	ENGINEERS GATE MANAGER LP	0.09%	24.75K	549.34K	24.75K	+100.00%
Jun 30, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.09%	26.83K	595.6K	-4.35K	-13.95%
Jun 30, 2025	AQR CAPITAL MANAGEMENT LLC	0.1%	27.72K	615.43M	-2.29K	-7.63%
Jun 30, 2025	ALLIANCEBERNSTEIN L.P.	0.11%	30.52K	677.54M	0	0
Jun 30, 2025	XTX TOPCO LTD	0.11%	30.64K	680.25K	30.64K	+100.00%
Jun 30, 2025	SUSQUEHANNA PORTFOLIO STRATEGIES, LLC	0.11%	32.8K	728.23K	32.8K	+100.00%
Jun 30, 2025	SKANDINAVISKA ENSKILDA BANKEN AB (PUBL)	0.12%	33.52K	744.21K	0	0
Jun 30, 2025	SAVANT CAPITAL, LLC	0.04%	10.87K	241.29K	10.87K	+100.00%
Jun 30, 2025	NEOS INVESTMENT MANAGEMENT LLC	0.04%	11.4K	253.17K	11.4K	+100.00%
Jun 30, 2025	BLEAKLEY FINANCIAL GROUP, LLC	0.13%	37.55K	833.63K	37.55K	+100.00%
Jun 30, 2025	UBS OCONNOR LLC	0.13%	38.53K	855.32K	-8.52K	-18.11%
Jun 30, 2025	PDT PARTNERS, LLC	0.15%	44.47K	987.12K	-64	-0.14%
Jun 30, 2025	DCF ADVISERS, LLC	0.17%	48K	1.07M	13.15K	+37.73%
Mar 31, 2025	CAMBER CAPITAL MANAGEMENT LP	2.45%	750K	13.94M	-500K	-40.00%
Mar 31, 2025	NORTHERN TRUST CORP	0.69%	212.89K	3.96M	-7.1K	-3.23%
Mar 31, 2025	TREXQUANT INVESTMENT LP	0.5%	153.56K	2.85M	92.84K	+152.90%
Mar 31, 2025	ECOR1 CAPITAL, LLC	25.72%	7.88M	146.49M	6.65K	+0.08%
Mar 31, 2025	FMR LLC	6.22%	1.91M	35.42M	-1.13M	-37.13%
Mar 31, 2025	SANOFI	2.68%	821.92K	15.28M	0	0
Mar 31, 2025	WOODLINE PARTNERS LP	2.58%	791.02K	14.71M	305.95K	+63.07%
Mar 31, 2025	MORGAN STANLEY	1.65%	504.64K	9.38M	288.72K	+133.72%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.6%	491.17K	9.13M	4.57K	+0.94%
Mar 31, 2025	UBS GROUP AG	1.6%	490.27K	9.11M	453.67K	+1,239.32%
Mar 31, 2025	VICTORY CAPITAL MANAGEMENT INC	1.33%	406.43K	7.56M	71.98K	+21.52%
Mar 31, 2025	FIRST LIGHT ASSET MANAGEMENT, LLC	15.12%	4.63M	86.14M	3.76M	+433.28%
Mar 31, 2025	CITADEL ADVISORS LLC	1.22%	372.57K	6.93M	198.84K	+114.46%
Mar 31, 2025	683 CAPITAL MANAGEMENT, LLC	0.64%	195.63K	3.64M	195.63K	+100.00%
Mar 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.25%	76.02K	1.41M	9.55K	+14.37%
Mar 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.23%	70.8K	1.32M	-222.9K	-75.89%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	3.73%	1.14M	21.27M	1.13M	+6,273.39%
Mar 31, 2025	CITIGROUP INC	3.5%	1.07M	19.91M	1.02M	+1,892.02%
Mar 31, 2025	PALO ALTO INVESTORS LP	3.33%	1.02M	18.98M	176.74K	+20.94%
Mar 31, 2025	5AM VENTURE MANAGEMENT, LLC	1.17%	357.73K	6.65M	0	0
Mar 31, 2025	FRANKLIN RESOURCES INC	1.16%	354.39K	6.59M	21	+0.01%
Mar 31, 2025	RENAISSANCE TECHNOLOGIES LLC	1.11%	338.7K	6.3M	145.5K	+75.31%
Mar 31, 2025	POINT72 ASSET MANAGEMENT, L.P.	7.73%	2.37M	44.03M	2.37M	+100.00%
Mar 31, 2025	BLACKROCK, INC.	7.1%	2.18M	40.46M	-371.87K	-14.59%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.92%	280.58K	5.22M	-138.53K	-33.05%
Mar 31, 2025	TWO SIGMA ADVISERS, LP	0.87%	268.1K	4.98M	-25.2K	-8.59%
Mar 31, 2025	BANK OF NEW YORK MELLON CORP	0.2%	61.21K	1.14M	4.04K	+7.06%
Mar 31, 2025	TANG CAPITAL MANAGEMENT LLC	5.04%	1.55M	28.72M	214.27K	+16.10%
Mar 31, 2025	VANGUARD GROUP INC	4.95%	1.52M	28.21M	-326.42K	-17.70%
Mar 31, 2025	SOFINNOVA INVESTMENTS, INC.	3.79%	1.16M	21.57M	1.03M	+772.68%
Mar 31, 2025	TWO SIGMA INVESTMENTS, LP	0.87%	265.86K	4.94M	-86.18K	-24.48%
Mar 31, 2025	OPALEYE MANAGEMENT INC.	0.82%	250.93K	4.66M	250.93K	+100.00%
Mar 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	2.99%	915.08K	17.01M	-9.93K	-1.07%
Mar 31, 2025	STATE STREET CORP	2.81%	860.72K	16M	-425.03K	-33.06%
Mar 31, 2025	MACQUARIE GROUP LTD	0.31%	93.73K	1.74M	0	0
Mar 31, 2025	D. E. SHAW & CO., INC.	0.42%	129.65K	2.41M	-67.45K	-34.22%
Mar 31, 2025		0.32%	96.8K	1.8M	-118.2K	-54.98%
Mar 31, 2025	EXOME ASSET MANAGEMENT LLC	0.38%	116.62K	2.17M	116.62K	+100.00%
Mar 31, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	0.33%	102.05K	1.9M	-311.95K	-75.35%
Mar 31, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.32%	96.97K	1.8M	96.97K	+100.00%
Mar 31, 2025	MARSHALL WACE, LLP	0.3%	92.87K	1.73M	92.87K	+100.00%
Mar 31, 2025	HIGHMARK WEALTH MANAGEMENT LLC	0.3%	92K	1.71M	92K	+100.00%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.5%	153.36K	2.85M	-12.7K	-7.65%
Mar 31, 2025	GRANAHAN INVESTMENT MANAGEMENT, LLC	0.48%	146.49K	2.72M	40.41K	+38.10%
Mar 31, 2025	MOODY ALDRICH PARTNERS LLC	0.27%	83.22K	1.55M	83.22K	+100.00%
Mar 31, 2025	ASSENAGON ASSET MANAGEMENT S.A.	0.79%	242.49K	4.51M	-89.27K	-26.91%
Mar 31, 2025	ENSIGN PEAK ADVISORS, INC	0.7%	215.45K	4.01M	0	0
Mar 31, 2024	CITADEL ADVISORS LLC	1.21%	324.75K	7.31M	209.77K	+182.45%
Mar 31, 2024	CITIGROUP INC	0.29%	79.04K	1.78M	75.42K	+2,083.51%
Mar 31, 2024	UBS OCONNOR LLC	0.31%	83.03K	1.87M	-4.1K	-4.70%
Mar 31, 2024	RAFFERTY ASSET MANAGEMENT, LLC	0.34%	90.69K	2.04M	90.69K	+100.00%
Mar 31, 2024	MORGAN STANLEY	2.36%	636.11K	14.33M	34.08K	+5.66%
Mar 31, 2024	SATURN V CAPITAL MANAGEMENT LLC	2.18%	586.03K	13.2M	-78.25K	-11.78%
Mar 31, 2024	DIMENSIONAL FUND ADVISORS LP	1.75%	469.86K	10.58M	-128.03K	-21.41%
Mar 31, 2024	NORTHERN TRUST CORP	0.75%	201.15K	4.53M	-6K	-2.90%
Mar 31, 2024	D. E. SHAW & CO., INC.	0.69%	186.8K	4.21M	26.48K	+16.52%
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	0.64%	171.69K	3.87M	-60.07K	-25.92%
Mar 31, 2024	OCTAGON CAPITAL ADVISORS LP	0.61%	165K	3.72M	45K	+37.50%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.56%	150.43K	3.39M	10.93K	+7.84%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.54%	146.27K	3.29M	1.45K	+1.00%
Mar 31, 2024	FMR LLC	0.52%	140.75K	3.17M	-61.97K	-30.57%
Mar 31, 2024	HUDSON BAY CAPITAL MANAGEMENT LP	0.49%	132.5K	2.98M	37.5K	+39.47%
Mar 31, 2024	TWO SIGMA ADVISERS, LP	0.49%	131.7K	2.97M	32.5K	+32.76%
Mar 31, 2024	TWO SIGMA INVESTMENTS, LP	0.45%	119.97K	2.7M	32.44K	+37.06%
Mar 31, 2024	RENAISSANCE TECHNOLOGIES LLC	0.37%	100.2K	2.26M	4.6K	+4.81%
Mar 31, 2024	MACQUARIE GROUP LTD	0.35%	93.73K	2.11M	0	0
Mar 31, 2024	JACOBS LEVY EQUITY MANAGEMENT, INC	0.18%	49.39K	1.11M	13.76K	+38.64%
Mar 31, 2024	ASSENAGON ASSET MANAGEMENT S.A.	0.82%	221.84K	5M	0	0
Mar 31, 2024	MILLENNIUM MANAGEMENT LLC	2.4%	647.13K	14.57M	240.09K	+58.99%
Mar 31, 2024	MANGROVE PARTNERS	2.56%	689.52K	15.53M	689.52K	+100.00%
Mar 31, 2024	VANGUARD GROUP INC	5.03%	1.35M	30.49M	-26.11K	-1.89%
Mar 31, 2024	BLACKROCK INC.	6.39%	1.72M	38.74M	-79.77K	-4.43%
Mar 31, 2024	SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC	0.2%	54.21K	1.22M	54.21K	+100.00%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.2%	54.53K	1.23M	29.11K	+114.54%
Mar 31, 2024	WELLINGTON MANAGEMENT GROUP LLP	0.22%	59.05K	1.33M	59.05K	+100.00%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.24%	64.09K	1.44M	-5.95K	-8.49%
Mar 31, 2024	UBS GROUP AG	0.24%	64.17K	1.45M	45.42K	+242.36%
Mar 31, 2024	STEMPOINT CAPITAL LP	1%	269.55K	6.07M	224.55K	+499.00%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.24%	64.24K	1.45M	11.13K	+20.95%
Mar 31, 2024	BLACKSTONE INC.	1.22%	328.72K	7.4M	0	0
Mar 31, 2024	PLATINUM INVESTMENT MANAGEMENT LTD	0.25%	66.15K	1.49M	66.15K	+100.00%
Mar 31, 2024	FISHER ASSET MANAGEMENT, LLC	0.26%	70.65K	1.59M	-500	-0.70%
Mar 31, 2024	5AM VENTURE MANAGEMENT, LLC	1.33%	357.73K	8.06M	0	0
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	1.57%	421.7K	9.5M	1.6K	+0.38%
Mar 31, 2024	EVENTIDE ASSET MANAGEMENT, LLC	1.59%	427K	9.62M	0	0
Mar 31, 2024	FRANKLIN RESOURCES INC	1.73%	465.37K	10.48M	60.26K	+14.87%
Mar 31, 2024	WOODLINE PARTNERS LP	1.89%	508.84K	11.46M	-686.14K	-57.42%
Mar 31, 2024	DEEP TRACK CAPITAL, LP	1.97%	529.45K	11.92M	-1.51M	-74.01%
Mar 31, 2024	PALO ALTO INVESTORS LP	2.97%	799.91K	18.01M	113.02K	+16.45%
Mar 31, 2024	POINT72 ASSET MANAGEMENT, L.P.	3.21%	864.1K	19.46M	75.56K	+9.58%
Mar 31, 2024	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	3.34%	899.7K	20.26M	0	0
Mar 31, 2024	FIRST LIGHT ASSET MANAGEMENT, LLC	3.51%	944.11K	21.26M	-293.07K	-23.69%
Mar 31, 2024	GREAT POINT PARTNERS LLC	3.63%	976.98K	22M	0	0
Mar 31, 2024	STATE STREET CORP	4.48%	1.21M	27.19M	763.06K	+171.73%
Mar 31, 2024	BOXER CAPITAL, LLC	4.83%	1.3M	29.28M	0	0
Mar 31, 2024	TANG CAPITAL MANAGEMENT LLC	4.94%	1.33M	29.97M	-619.73K	-31.77%
Mar 31, 2024	ECOR1 CAPITAL, LLC	27.93%	7.52M	169.37M	0	0
Mar 31, 2024	NEW YORK STATE COMMON RETIREMENT FUND	0.03%	7.91K	178K	-11	-0.14%
Mar 31, 2024	RUSSELL INVESTMENTS GROUP, LTD.	0.03%	8.15K	183.47K	-390	-4.57%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.03%	8.96K	201.78K	8.96K	+100.00%
Mar 31, 2024	ALGERT GLOBAL LLC	0.03%	9.1K	205K	9.1K	+100.00%
Mar 31, 2024	AMERICAN INTERNATIONAL GROUP, INC.	0.03%	9.23K	207.91K	-80	-0.86%
Mar 31, 2024	METLIFE INVESTMENT MANAGEMENT, LLC	0.04%	11.04K	248.69K	0	0
Mar 31, 2024	MIRAE ASSET GLOBAL INVESTMENTS CO., LTD.	0.05%	12.13K	265.28K	12.13K	+100.00%
Mar 31, 2024	JPMORGAN CHASE & CO	0.05%	13.37K	301.18K	-4.12K	-23.56%
Mar 31, 2024	VERITION FUND MANAGEMENT LLC	0.05%	13.47K	303.39K	13.47K	+100.00%
Mar 31, 2024	LEGAL & GENERAL GROUP PLC	0.05%	13.8K	310.78M	-2.5K	-15.36%
Mar 31, 2024	PROFUND ADVISORS LLC	0.05%	14.15K	318.57M	14.15K	+100.00%
Mar 31, 2024	XTX TOPCO LTD	0.06%	15.7K	353.65K	5.02K	+47.03%
Mar 31, 2024	BALYASNY ASSET MANAGEMENT L.P.	0.06%	15.75K	354.6K	-3.2K	-16.90%
Mar 31, 2024	CREDIT SUISSE AG/	0.06%	15.81K	356.11K	-5.28K	-25.03%
Mar 31, 2024	BNP PARIBAS ARBITRAGE, SNC	0.06%	16.52K	372.03K	-4.43K	-21.16%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.06%	16.89K	380.45K	-10.34K	-37.97%
Mar 31, 2024	ACADIAN ASSET MANAGEMENT LLC	0.07%	18.67K	420K	18.67K	+100.00%
Mar 31, 2024	ALPS ADVISORS INC	0.07%	18.75K	422.18K	679	+3.76%
Mar 31, 2024	INVESCO LTD.	0.07%	20.08K	452.09K	10.36K	+106.58%
Mar 31, 2024	SWISS NATIONAL BANK	0.08%	21K	472.92K	-5.2K	-19.85%
Mar 31, 2024	TD ASSET MANAGEMENT INC	0.08%	22.6K	508.95M	-8.8K	-28.03%
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	0.11%	28.53K	642.5K	-2.06K	-6.73%
Mar 31, 2024	QUBE RESEARCH & TECHNOLOGIES LTD	0.11%	28.54K	642.77K	25.9K	+981.55%
Mar 31, 2024	MARTINGALE ASSET MANAGEMENT L P	0.11%	28.64K	644.86K	16	+0.06%
Mar 31, 2024	RHUMBLINE ADVISERS	0.11%	29.19K	657.34K	-203	-0.69%
Mar 31, 2024	TREXQUANT INVESTMENT LP	0.12%	32.52K	732.28K	10.69K	+48.94%
Mar 31, 2024	FEDERATED HERMES, INC.	0.13%	36.04K	811.64K	14	+0.04%
Mar 31, 2024	VICTORY CAPITAL MANAGEMENT INC	0.14%	36.68K	826.03K	-6.46K	-14.97%
Mar 31, 2024	ENSIGN PEAK ADVISORS, INC	0.16%	43.44K	978.31K	0	0
Dec 31, 2023	DEEP TRACK CAPITAL, LP	7.67%	2.04M	43.63M	691.18K	+51.36%
Dec 31, 2023	ALLIANCEBERNSTEIN L.P.	0.12%	30.59K	655.24K	0	0
Dec 31, 2023	TD ASSET MANAGEMENT INC	0.12%	31.4K	672.59K	0	0
Dec 31, 2023	ECOR1 CAPITAL, LLC	28.33%	7.52M	161.1M	0	0
Dec 31, 2023	MARSHALL WACE, LLP	0.13%	33.36K	714.51K	-1.52K	-4.36%
Dec 31, 2023	JACOBS LEVY EQUITY MANAGEMENT, INC	0.13%	35.63K	763.09K	-171.16K	-82.77%
Dec 31, 2023	FEDERATED HERMES, INC.	0.14%	36.03K	771.7K	0	0
Dec 31, 2023	VICTORY CAPITAL MANAGEMENT INC	0.16%	43.14K	924.06K	-550	-1.26%
Dec 31, 2023	ENSIGN PEAK ADVISORS, INC	0.16%	43.44K	930.53K	0	0
Dec 31, 2023		0.17%	45K	963.9K	45K	+100.00%
Dec 31, 2023	NUVEEN ASSET MANAGEMENT, LLC	0.2%	53.11K	1.14M	-19.45K	-26.81%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.26%	70.04K	1.5M	631	+0.91%
Dec 31, 2023	FISHER ASSET MANAGEMENT, LLC	0.27%	71.15K	1.52M	500	+0.71%
Dec 31, 2023	HRT FINANCIAL LP	0.28%	75.63K	1.62M	75.63K	+100.00%
Dec 31, 2023	UBS OCONNOR LLC	0.33%	87.12K	1.87M	-37.34K	-30.00%
Dec 31, 2023	TWO SIGMA INVESTMENTS, LP	0.33%	87.53K	1.87M	-20.09K	-18.67%
Dec 31, 2023	MACQUARIE GROUP LTD	0.35%	93.73K	2.01M	0	0
Dec 31, 2023	HUDSON BAY CAPITAL MANAGEMENT LP	0.36%	95K	2.03M	-5K	-5.00%
Dec 31, 2023	RENAISSANCE TECHNOLOGIES LLC	0.36%	95.6K	2.05M	2.9K	+3.13%
Dec 31, 2023	TWO SIGMA ADVISERS, LP	0.37%	99.2K	2.12M	-17.9K	-15.29%
Dec 31, 2023	CITADEL ADVISORS LLC	0.43%	114.97K	2.46M	-71.5K	-38.34%
Dec 31, 2023	OCTAGON CAPITAL ADVISORS LP	0.45%	120K	2.57M	120K	+100.00%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.53%	139.5K	2.99M	-38.9K	-21.80%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.55%	144.82K	3.1M	1.81K	+1.26%
Dec 31, 2023	D. E. SHAW & CO., INC.	0.6%	160.33K	3.43M	14.43K	+9.89%
Dec 31, 2023	FMR LLC	0.76%	202.71K	4.34M	-64.9K	-24.25%
Dec 31, 2023	NORTHERN TRUST CORP	0.78%	207.15K	4.44M	6.97K	+3.48%
Dec 31, 2023	ASSENAGON ASSET MANAGEMENT S.A.	0.84%	221.84K	4.75M	0	0
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	0.87%	231.75K	4.97M	5.47K	+2.42%
Dec 31, 2023	BLACKSTONE INC.	1.24%	328.72K	7.04M	0	0
Dec 31, 2023	SUVRETTA CAPITAL MANAGEMENT, LLC	1.34%	354.87K	7.6M	-124.57K	-25.98%
Dec 31, 2023	5AM VENTURE MANAGEMENT, LLC	1.35%	357.73K	7.66M	0	0
Dec 31, 2023	FRANKLIN RESOURCES INC	1.53%	405.12K	8.68M	75.03K	+22.73%
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	1.53%	407.03K	8.72M	-39.19K	-8.78%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.58%	420.11K	9M	20.51K	+5.13%
Dec 31, 2023	EVENTIDE ASSET MANAGEMENT, LLC	1.61%	427K	9.15M	0	0
Dec 31, 2023	STATE STREET CORP	1.67%	444.35K	9.52M	-489.02K	-52.39%
Dec 31, 2023	DIMENSIONAL FUND ADVISORS LP	2.25%	597.89K	12.81M	-88.57K	-12.90%
Dec 31, 2023	MORGAN STANLEY	2.27%	602.03K	12.9M	521.05K	+643.37%
Dec 31, 2023	SATURN V CAPITAL MANAGEMENT LLC	2.5%	664.28K	14.23M	87.18K	+15.11%
Dec 31, 2023	PALO ALTO INVESTORS LP	2.59%	686.88K	14.71M	255.66K	+59.29%
Dec 31, 2023	POINT72 ASSET MANAGEMENT, L.P.	2.97%	788.55K	16.89M	-2.66K	-0.34%
Dec 31, 2023	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	3.39%	899.7K	19.27M	0	0
Dec 31, 2023	GREAT POINT PARTNERS LLC	3.68%	976.98K	20.93M	82.65K	+9.24%
Dec 31, 2023	WOODLINE PARTNERS LP	4.5%	1.19M	25.6M	354.15K	+42.12%
Dec 31, 2023	FIRST LIGHT ASSET MANAGEMENT, LLC	4.66%	1.24M	26.5M	446.37K	+56.45%
Dec 31, 2023	BOXER CAPITAL, LLC	4.9%	1.3M	27.85M	0	0
Dec 31, 2023	VANGUARD GROUP INC	5.2%	1.38M	29.56M	-322.67K	-18.95%
Dec 31, 2023	BLACKROCK INC.	6.78%	1.8M	38.55M	-24.07K	-1.32%
Dec 31, 2023	TANG CAPITAL MANAGEMENT LLC	7.35%	1.95M	41.78M	0	0
Sep 30, 2023	RAFFERTY ASSET MANAGEMENT, LLC	0.23%	62.34K	-	-30.31K	-32.72%
Sep 30, 2023	FISHER ASSET MANAGEMENT, LLC	0.27%	70.65K	-	0	0
Sep 30, 2023	NUVEEN ASSET MANAGEMENT, LLC	0.27%	72.57K	-	159	+0.22%
Sep 30, 2023	MORGAN STANLEY	0.3%	80.99K	-	9.37K	+13.08%
Sep 30, 2023	HUDSON BAY CAPITAL MANAGEMENT LP	0.38%	100K	-	50K	+100.00%
Sep 30, 2023	BAKER BROS. ADVISORS LP	0.4%	106.2K	-	-669.73K	-86.31%
Sep 30, 2023	TWO SIGMA INVESTMENTS, LP	0.4%	107.62K	-	-38.52K	-26.36%
Sep 30, 2023	TWO SIGMA ADVISERS, LP	0.44%	117.1K	-	-8.9K	-7.06%
Sep 30, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.54%	143.01K	-	3.4K	+2.43%
Sep 30, 2023	D. E. SHAW & CO., INC.	0.55%	145.89K	-	-59.9K	-29.11%
Sep 30, 2023	GOLDMAN SACHS GROUP INC	0.67%	178.4K	-	46.37K	+35.12%
Sep 30, 2023	NORTHERN TRUST CORP	0.75%	200.18K	-	-2.39K	-1.18%
Sep 30, 2023	JACOBS LEVY EQUITY MANAGEMENT, INC	0.78%	206.79K	-	8.06K	+4.06%
Sep 30, 2023	ASSENAGON ASSET MANAGEMENT S.A.	0.83%	221.84K	-	-273.22K	-55.19%
Sep 30, 2023	FMR LLC	1%	267.62K	-	-25.95K	-8.84%
Sep 30, 2023	BLACKSTONE INC.	1.23%	328.72K	-	0	0
Sep 30, 2023	FRANKLIN RESOURCES INC	1.24%	330.09K	-	330.09K	+100.00%
Sep 30, 2023	5AM VENTURE MANAGEMENT, LLC	1.34%	357.73K	-	0	0
Sep 30, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.5%	399.59K	-	3.57K	+0.90%
Sep 30, 2023	EVENTIDE ASSET MANAGEMENT, LLC	1.6%	427K	-	427K	+100.00%
Sep 30, 2023	SATURN V CAPITAL MANAGEMENT LLC	2.17%	577.1K	-	577.1K	+100.00%
Sep 30, 2023	DIMENSIONAL FUND ADVISORS LP	2.58%	686.46K	-	-218.45K	-24.14%
Sep 30, 2023	POINT72 ASSET MANAGEMENT, L.P.	2.97%	791.2K	-	-668.71K	-45.80%
Sep 30, 2023	WOODLINE PARTNERS LP	3.16%	840.82K	-	-193.73K	-18.73%
Sep 30, 2023	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	3.38%	899.7K	-	0	0
Sep 30, 2023	BLACKROCK INC.	6.85%	1.82M	-	-813	-0.04%
Sep 30, 2023	UBS GROUP AG	0.07%	17.59K	-	-17.61K	-50.04%
Sep 30, 2023	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.07%	18.49K	-	18.49K	+100.00%
Sep 30, 2023	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0.07%	19.37K	-	-4.15K	-17.65%
Sep 30, 2023	ALPS ADVISORS INC	0.07%	19.57K	-	104	+0.53%
Sep 30, 2023	PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO	0.09%	23.14K	-	0	0
Sep 30, 2023	CREDIT SUISSE AG/	0.09%	23.49K	-	-2.46K	-9.49%
Sep 30, 2023	BNP PARIBAS ARBITRAGE, SNC	0.09%	23.8K	-	4.37K	+22.47%
Sep 30, 2023	ECOR1 CAPITAL, LLC	28.24%	7.52M	-	0	0
Sep 30, 2023	CAPTION MANAGEMENT, LLC	0.09%	25K	-	-2K	-7.41%
Sep 30, 2023	JANE STREET GROUP, LLC	0.1%	25.67K	-	25.67K	+100.00%
Sep 30, 2023	RHUMBLINE ADVISERS	0.11%	30.2K	-	-191	-0.63%
Sep 30, 2023	ALLIANCEBERNSTEIN L.P.	0.11%	30.59K	-	-1.93K	-5.93%
Sep 30, 2023	TD ASSET MANAGEMENT INC	0.12%	31.4K	-	31.4K	+100.00%
Sep 30, 2023	CITIGROUP INC	0.13%	35.13K	-	1.33K	+3.95%
Sep 30, 2023	FEDERATED HERMES, INC.	0.14%	36.03K	-	-17	-0.05%
Sep 30, 2023	BARCLAYS PLC	0.14%	36.07K	-	-12.59K	-25.88%
Sep 30, 2023	SWISS NATIONAL BANK	0.14%	37.9K	-	-4.7K	-11.03%
Sep 30, 2023	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.15%	40.54K	-	-48.05K	-54.24%
Sep 30, 2023	ENSIGN PEAK ADVISORS, INC	0.16%	43.44K	-	0	0
Sep 30, 2023	VICTORY CAPITAL MANAGEMENT INC	0.16%	43.69K	-	43.69K	+100.00%
Sep 30, 2023	AMERIPRISE FINANCIAL INC	0.17%	44.92K	-	-42.95K	-48.88%
Sep 30, 2023	BANK OF NEW YORK MELLON CORP	0.26%	69.41K	-	24	+0.03%

Insiders

Among the ANAB insiders holding of 5.76% of the stake in company, ECOR1 CAPITAL, LLC, , holds the largest shares of 7.88M. NODELMAN OLEG, , is the second largest ANAB insider with ownership of 7.52M shares. NOVO A/S, 10 percent owner, stands third with possession of 3.03M shares of that stake.

Insiders	Designation	Shares Held
ECOR1 CAPITAL, LLC		7.88M
NODELMAN OLEG		7.52M
NOVO A/S	10 percent owner	3.03M
NOVO HOLDINGS A/S	10 percent owner	1.94M
FAGA DANIEL	President, CEO	466.79K
FRAZIER HEALTHCARE VII, L.P.	10 percent owner	311.29K
TOPPER JAMES N		297.8K
LYDON NICHOLAS	director	271.11K
FRAZIER HEALTHCARE V, LP	10 percent owner	88.71K
SURIA HAMZA	President, CEO	68.6K
LIZZUL PAUL F.	Chief Medical Officer	37.21K
LONDEI MARCO	Chief Medical Officer	22.38K
MULROY DENNIS	CHIEF FINANCIAL OFFICER	17.67K
WARE J. ANTHONY	director	9.63K
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	9.16K
RENTON HOLLINGS	director	4.97K
FENTON DENNIS M	director	4.97K
AVALON VENTURES VII L P	10 percent owner	0
PISCITELLI DOMINIC	Chief Financial Officer	0

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Jan 07, 2026	LOUMEAU ERIC J	SALE	47.23	500	23.62K	9.16K
Jan 07, 2026	MULROY DENNIS	SALE	45.11	1.91K	86.07K	17.67K
Jan 07, 2026	FAGA DANIEL	SALE	45.11	9.2K	415.1K	466.79K
Jan 07, 2026	LIZZUL PAUL F.	SALE	45.11	2.24K	100.82K	37.21K
Jan 05, 2026	FAGA DANIEL	SALE	43.26	15.31K	662.27K	458.14K
Jan 05, 2026	LOUMEAU ERIC J	SALE	43.26	2.98K	129.04K	13.25K
Jan 05, 2026	MULROY DENNIS	SALE	43.26	3.36K	145.48K	14.33K
Jan 05, 2026	LIZZUL PAUL F.	SALE	43.26	4.22K	182.51K	33.3K
Dec 23, 2025	WARE J. ANTHONY	SALE	49.58	3.9K	193.34K	9.63K
Dec 22, 2025	LOUMEAU ERIC J	SALE	51.00	10K	510K	8.95K
Dec 22, 2025	LIZZUL PAUL F.	SALE	50.00	1.5K	75K	26.97K
Dec 22, 2025	MULROY DENNIS	SALE	50.00	10K	500K	9.4K
Dec 18, 2025	LOUMEAU ERIC J	SALE	46.99	141	6.63K	8.95K
Dec 17, 2025	LOUMEAU ERIC J	SALE	46.00	10K	460K	9.09K
Dec 16, 2025	MULROY DENNIS	SALE	45.21	6.36K	287.51K	9.4K
Dec 16, 2025	LOUMEAU ERIC J	SALE	45.24	4.2K	189.77K	9.09K
Sep 30, 2025	LOUMEAU ERIC J	SALE	29.00	8.24K	238.96K	9.09K
Aug 08, 2025	RENTON HOLLINGS	SALE	19.70	7.12K	140.26K	4.97K
Jul 02, 2025	RENTON HOLLINGS	SALE	23.82	13.68K	325.78K	4.97K
Jun 18, 2025	RENTON HOLLINGS	SALE	23.97	3.02K	72.27K	4.97K
Jun 18, 2025	FENTON DENNIS M	SALE	23.97	3.02K	72.27K	4.97K
Jan 02, 2025	ECOR1 CAPITAL, LLC	PURCHASE	12.95	6.65K	86.07K	7.88M
Dec 31, 2024	ECOR1 CAPITAL, LLC	PURCHASE	12.93	13.27K	171.51K	7.87M
Dec 30, 2024	ECOR1 CAPITAL, LLC	PURCHASE	12.92	65.18K	842.06K	7.86M
Nov 29, 2024	RENTON HOLLINGS	SALE	25.00	10K	250K	1.95K
Sep 23, 2024	LIZZUL PAUL F.	SALE	38.67	1.5K	58.01K	15.4K
Sep 17, 2024	LOUMEAU ERIC J	SALE	38.41	3.78K	145.19K	3.24K
Sep 16, 2024	MULROY DENNIS	SALE	40.13	10K	401.3K	4.74K
Sep 16, 2024	LOUMEAU ERIC J	SALE	40.13	6.5K	260.85K	7.02K
Sep 16, 2024	LIZZUL PAUL F.	SALE	38.93	2.22K	86.42K	15.4K
Aug 14, 2024	ECOR1 CAPITAL, LLC	PURCHASE	36.50	273.97K	10M	7.79M
Aug 14, 2024	LIZZUL PAUL F.	SALE	40.00	2K	80K	11.62K
Jul 18, 2024	LIZZUL PAUL F.	SALE	35.00	1.5K	52.5K	11.62K
Jul 15, 2024	RENTON HOLLINGS	SALE	30.98	2.9K	89.75K	1.95K
Jun 21, 2024	FENTON DENNIS M	SALE	23.17	1.95K	45.18K	1.95K
Jun 18, 2024	RENTON HOLLINGS	SALE	23.16	1.95K	45.16K	1.95K
May 22, 2024	MULROY DENNIS	SALE	23.72	1.5K	35.58K	964
Mar 25, 2024	FAGA DANIEL	SALE	21.42	3K	64.27K	749.09K
Mar 22, 2024	FAGA DANIEL	SALE	22.78	145.94K	3.33M	752.09K
Feb 16, 2024	LOUMEAU ERIC J	SALE	25.00	5K	125K	3.24K
Jan 30, 2024	MULROY DENNIS	SALE	23.63	3.07K	72.43K	964
Jan 08, 2024	FAGA DANIEL	SALE	21.81	6.87K	149.75K	898.03K
Jan 08, 2024	MULROY DENNIS	SALE	21.81	2.18K	47.55K	4.03K
Jan 08, 2024	LIZZUL PAUL F.	SALE	21.81	2.55K	55.7K	10.12K
Jan 08, 2024	LOUMEAU ERIC J	SALE	21.81	2.31K	50.27K	3.24K
Nov 22, 2023	LOUMEAU ERIC J	SALE	14.19	882	12.52K	0
Sep 18, 2023	MULROY DENNIS	SALE	19.32	3.9K	75.24K	964
Sep 18, 2023	LOUMEAU ERIC J	SALE	19.32	3.9K	75.23K	882
Sep 14, 2023	LIZZUL PAUL F.	SALE	19.48	2.11K	41.01K	6.53K
Sep 14, 2023	LOUMEAU ERIC J	SALE	19.48	2.11K	41.01K	4.78K
Sep 14, 2023	MULROY DENNIS	SALE	19.48	2.11K	41.01K	4.86K
Aug 08, 2022	LOUMEAU ERIC J	SALE	25.00	523	13.08K	0
Jun 08, 2022	LOUMEAU ERIC J	SALE	24.00	2.5K	60K	523
May 18, 2022	LOUMEAU ERIC J	SALE	20.50	1.15K	23.49K	523
May 05, 2022	ECOR1 CAPITAL, LLC	SALE	21.63	668.24K	14.45M	7.52M
May 05, 2022	NODELMAN OLEG	PURCHASE	21.63	668.24K	14.45M	7.52M
Dec 20, 2021	SURIA HAMZA	SALE	36.40	5.52K	201.03K	68.6K
Nov 05, 2021	SURIA HAMZA	SALE	35.00	14.3K	500.57K	67.64K
Nov 04, 2021	LOUMEAU ERIC J	SALE	35.00	5K	175K	0
Nov 01, 2021	SURIA HAMZA	SALE	32.88	2.56K	84.14K	67.64K
Oct 26, 2021	SURIA HAMZA	SALE	30.00	15.99K	479.79K	67.64K
May 04, 2021	ECOR1 CAPITAL, LLC	PURCHASE	23.25	165K	3.84M	7.52M
May 03, 2021	ECOR1 CAPITAL, LLC	PURCHASE	23.31	20.8K	484.87K	7.36M
Apr 30, 2021	ECOR1 CAPITAL, LLC	PURCHASE	23.16	35.7K	826.82K	7.33M
Apr 27, 2021	ECOR1 CAPITAL, LLC	PURCHASE	23.82	33.8K	805.09K	7.3M
Apr 26, 2021	ECOR1 CAPITAL, LLC	PURCHASE	23.80	13.9K	330.86K	7.27M
Apr 23, 2021	ECOR1 CAPITAL, LLC	PURCHASE	23.54	99.6K	2.34M	7.25M
Mar 09, 2021	ECOR1 CAPITAL, LLC	PURCHASE	18.70	531K	9.93M	7.15M
Mar 08, 2021	ECOR1 CAPITAL, LLC	PURCHASE	18.97	2.78M	52.69M	6.62M
Feb 23, 2021	ECOR1 CAPITAL, LLC	PURCHASE	25.48	29.5K	751.66K	3.84M
Feb 12, 2021	LOUMEAU ERIC J	SALE	35.00	10K	350K	0
Dec 10, 2019	WARE J. ANTHONY	PURCHASE	14.05	3.6K	50.58K	3.6K
Jun 10, 2019	SURIA HAMZA	SALE	76.31	454	34.64K	17.64K
Jun 04, 2019	LONDEI MARCO	SALE	74.50	2K	149.22K	22.38K
Jan 15, 2019	LONDEI MARCO	SALE	70.04	14.89K	1.04M	22.38K
Jan 14, 2019	SURIA HAMZA	SALE	71.10	12.24K	870.3K	30.06K
Dec 17, 2018	LONDEI MARCO	SALE	68.47	6.74K	461.58K	144.88K
Dec 14, 2018	SURIA HAMZA	SALE	70.51	7.8K	549.98K	30.06K
Dec 12, 2018	SURIA HAMZA	SALE	72.88	8.32K	606.62K	30.06K
Dec 11, 2018	SURIA HAMZA	SALE	70.83	5K	354.01K	30.06K
Dec 10, 2018	SURIA HAMZA	SALE	72.48	4.96K	359.81K	35.06K
Dec 03, 2018	PISCITELLI DOMINIC	SALE	75.81	1.1K	83.39K	0
Apr 16, 2018	LYDON NICHOLAS	SALE	90.26	2.22K	200.55K	271.11K
Aug 21, 2017	NOVO HOLDINGS A/S	SALE	21.10	356.3K	7.52M	1.94M
Aug 15, 2017	NOVO HOLDINGS A/S	SALE	21.00	143.43K	3.01M	2.29M
Aug 14, 2017	NOVO HOLDINGS A/S	SALE	21.79	35.17K	766.49K	2.44M
Aug 07, 2017	NOVO HOLDINGS A/S	SALE	22.92	1.02K	23.44K	2.47M
Aug 04, 2017	NOVO HOLDINGS A/S	SALE	22.00	10.27K	225.96K	2.95M
Aug 03, 2017	NOVO HOLDINGS A/S	SALE	22.01	21.45K	472.19K	2.96M
Aug 02, 2017	NOVO HOLDINGS A/S	SALE	23.87	25.7K	613.48K	2.98M
Aug 01, 2017	NOVO HOLDINGS A/S	SALE	23.87	23.56K	562.27K	3.01M
Jul 26, 2017	AVALON VENTURES VII L P	SALE	24.35	37.04K	901.92K	0
Jan 31, 2017	FRAZIER HEALTHCARE VII, L.P.	PURCHASE	15.00	311.29K	4.67M	311.29K
Jan 31, 2017	LYDON NICHOLAS	PURCHASE	15.00	16.67K	249.99K	287.62K
Jan 31, 2017	TOPPER JAMES N	PURCHASE	15.00	88.71K	1.33M	297.8K
Jan 31, 2017	NOVO A/S	PURCHASE	15.00	50K	750K	3.03M
Jan 31, 2017	FRAZIER HEALTHCARE V, LP	PURCHASE	15.00	88.71K	1.33M	88.71K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES101.18K18

NET SHARES-101.18K18

SHARES HELD1.16M18

% NET SHARES-108.76%0%

Frequently Asked Questions

Stock Outstanding Shares

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares20.38

Short Percent Of Float38.69

Shares Outstanding27.69M

Shares Float14.42M

Shares Short5.64M

Short Ratio10.19

38.69%

Short % of Float

20.38%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

5.76% Percentage of Shares held by All Insiders

114.44% Percentage of Shares held by All Institutions

121.43% Percentage of Float held by Institutions

232

Number of Institutions Holding Shares

Institutional Ownership

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Sep 30, 2025	JANE STREET GROUP, LLC	0.63%	181.11K	5.55M	136.44K	+305.46%
Sep 30, 2025	PALO ALTO INVESTORS LP	2.34%	673.52K	20.62M	-139.3K	-17.14%
Sep 30, 2025	SANOFI	2.85%	821.92K	25.17M	0	0
Sep 30, 2025	ASSENAGON ASSET MANAGEMENT S.A.	2.92%	839.93K	25.72M	822.98K	+4,852.73%
Sep 30, 2025	VANGUARD GROUP INC	5.13%	1.48M	45.23M	-60.56K	-3.94%
Sep 30, 2025	MILLENNIUM MANAGEMENT LLC	5.27%	1.52M	46.52M	1.32M	+646.40%
Sep 30, 2025	WALLEYE CAPITAL LLC	0.2%	56.42K	1.73M	56.42K	+100.00%
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.2%	57.03K	1.75M	-2.2K	-3.71%
Sep 30, 2025	FISHER ASSET MANAGEMENT, LLC	0.2%	58.88K	1.8M	-21	-0.04%
Sep 30, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.21%	60.6K	1.86M	60.6K	+100.00%
Sep 30, 2025	BARCLAYS PLC	0.22%	63.45K	1.94M	-36.55K	-36.55%
Sep 30, 2025	FIRST LIGHT ASSET MANAGEMENT, LLC	3.44%	990.16K	30.32M	-2.55M	-72.03%
Sep 30, 2025	TANG CAPITAL MANAGEMENT LLC	4.63%	1.33M	40.84M	2.76K	+0.21%
Sep 30, 2025	MORGAN STANLEY	5.4%	1.56M	47.65M	-313.58K	-16.77%
Sep 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	7.86%	2.27M	69.37M	-209.35K	-8.46%
Sep 30, 2025	ECOR1 CAPITAL, LLC	27.35%	7.88M	241.29M	0	0
Sep 30, 2025	GOLDMAN SACHS GROUP INC	1.14%	329.82K	10.1M	49.99K	+17.86%
Sep 30, 2025	PANAGORA ASSET MANAGEMENT INC	0.22%	63.86K	1.96M	30.49K	+91.37%
Sep 30, 2025	UBS GROUP AG	0.26%	75.26K	2.3M	-1.2M	-94.09%
Sep 30, 2025	JUMP FINANCIAL, LLC	0.28%	82.08K	2.51M	82.08K	+100.00%
Sep 30, 2025	HIGHMARK WEALTH MANAGEMENT LLC	0.47%	135.05K	4.42M	-10.5K	-7.21%
Sep 30, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	2.17%	626.04K	19.17M	305K	+95.00%
Sep 30, 2025	BLACKROCK, INC.	5.98%	1.72M	52.74M	-64.61K	-3.62%
Sep 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.5%	144.6K	4.43M	-44.72K	-23.62%
Sep 30, 2025	IKARIAN CAPITAL, LLC	0.56%	161.1K	4.93M	161.1K	+100.00%
Sep 30, 2025	TWO SIGMA INVESTMENTS, LP	0.89%	256.42K	7.85M	25.05K	+10.83%
Sep 30, 2025	GRANAHAN INVESTMENT MANAGEMENT, LLC	0.51%	147.77K	4.52M	16.12K	+12.24%
Sep 30, 2025	SKANDINAVISKA ENSKILDA BANKEN AB (PUBL)	0.5%	145.19K	4.45M	111.67K	+333.11%
Sep 30, 2025	SECTORAL ASSET MANAGEMENT INC	0.68%	194.49K	5.96M	110.59K	+131.81%
Sep 30, 2025	ENSIGN PEAK ADVISORS, INC	0.75%	215.45K	6.6M	0	0
Sep 30, 2025	SOFINNOVA INVESTMENTS, INC.	0.88%	254.27K	7.79M	-778.09K	-75.37%
Sep 30, 2025	TWO SIGMA ADVISERS, LP	1.3%	373.7K	11.44M	83.3K	+28.68%
Sep 30, 2025	JACOBS LEVY EQUITY MANAGEMENT, INC	1.31%	378.45K	11.59M	10.01K	+2.72%
Sep 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.04%	299.31K	9.17M	-373.86K	-55.54%
Sep 30, 2025	ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	1.29%	370.46K	11.34M	219.65K	+145.65%
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.43%	123.3K	3.78M	-139.79K	-53.13%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.44%	127.24K	3.9M	-949.56K	-88.18%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.72%	206.44K	6.32M	49.31K	+31.38%
Sep 30, 2025	NUVEEN, LLC	1.18%	339.27K	10.39M	15.74K	+4.86%
Sep 30, 2025	D. E. SHAW & CO., INC.	1.21%	349.36K	10.7M	237.01K	+210.96%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.64%	473.63K	14.5M	10.27K	+2.22%
Sep 30, 2025	STATE STREET CORP	3.03%	873.43K	26.74M	52.4K	+6.38%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.37%	105.66K	3.24M	101.96K	+2,756.53%
Sep 30, 2025	NORTHERN TRUST CORP	0.68%	195.56K	5.99M	-700	-0.36%
Sep 30, 2025	VICTORY CAPITAL MANAGEMENT INC	0.71%	204.06K	6.25M	-328.03K	-61.65%
Sep 30, 2025	WOODLINE PARTNERS LP	1.74%	501.02K	15.34M	0	0
Sep 30, 2025	683 CAPITAL MANAGEMENT, LLC	1.9%	547K	16.75M	47K	+9.40%
Sep 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.04%	10.59K	324.14K	2.66K	+33.59%
Sep 30, 2025	TEMA ETFS LLC	0.04%	10.98K	336.06K	-429	-3.76%
Sep 30, 2025	NEOS INVESTMENT MANAGEMENT LLC	0.04%	10.98K	336.06K	-429	-3.76%
Sep 30, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.04%	11.93K	365.24K	11.93K	+100.00%
Sep 30, 2025	DEUTSCHE BANK AG\	0.04%	12.68K	388.29K	0	0
Sep 30, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.05%	12.96K	396.87K	-60.04K	-82.25%
Sep 30, 2025	ALPS ADVISORS INC	0.05%	13.34K	408.32K	-2.53K	-15.94%
Sep 30, 2025	BRINKER CAPITAL INVESTMENTS, LLC	0.05%	13.74K	420.69K	13.74K	+100.00%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0.05%	13.74K	420.81K	-19.59K	-58.76%
Sep 30, 2025	JPMORGAN CHASE & CO	0.05%	14.85K	454.77K	-232.77K	-94.00%
Sep 30, 2025	LOS ANGELES CAPITAL MANAGEMENT LLC	0.05%	14.88K	455.5K	-151	-1.00%
Sep 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.23%	66.73K	2.04M	-13.48K	-16.81%
Sep 30, 2025	SQUAREPOINT OPS LLC	0.24%	68.01K	2.08M	-41.37K	-37.82%
Sep 30, 2025	SEI INVESTMENTS CO	0.05%	14.92K	456.88K	14.92K	+100.00%
Sep 30, 2025	CRESSET ASSET MANAGEMENT, LLC	0.06%	16.89K	517.08K	3.72K	+28.27%
Sep 30, 2025	CAMPBELL & CO INVESTMENT ADVISER LLC	0.06%	18.28K	559.76K	18.28K	+100.00%
Sep 30, 2025	LEGAL & GENERAL GROUP PLC	0.07%	19.5K	597.21K	0	0
Sep 30, 2025	SWISS NATIONAL BANK	0.1%	28.4K	869.61K	2K	+7.58%
Sep 30, 2025	RHUMBLINE ADVISERS	0.1%	29.24K	895.44K	-1.46K	-4.76%
Sep 30, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.1%	30.09K	921.2K	3.26K	+12.14%
Sep 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0.12%	34.03K	1.04M	10.24K	+43.05%
Sep 30, 2025	GSA CAPITAL PARTNERS LLP	0.13%	37.27K	1.14M	-32.53K	-46.60%
Sep 30, 2025	BLEAKLEY FINANCIAL GROUP, LLC	0.14%	39.98K	1.22M	2.43K	+6.47%
Sep 30, 2025	INVESCO LTD.	0.15%	42.38K	1.3M	-40.79K	-49.05%
Sep 30, 2025	FRANKLIN RESOURCES INC	0.16%	47.33K	11.6M	-307.18K	-86.65%
Sep 30, 2025	DCF ADVISERS, LLC	0.17%	48K	1.47M	0	0
Sep 30, 2025	MOODY ALDRICH PARTNERS LLC	0.17%	49.88K	1.53M	-10.21K	-16.99%
Sep 30, 2025	FMR LLC	0.18%	53.16K	1.63M	-18.96K	-26.29%
Sep 30, 2025	MARSHALL WACE, LLP	0.19%	54.42K	1.67M	54.42K	+100.00%
Sep 30, 2025	ALGERT GLOBAL LLC	0.29%	83.77K	2.57M	83.77K	+100.00%
Sep 30, 2025	MACQUARIE GROUP LTD	0.33%	93.73K	2.87M	0	0
Sep 30, 2025	TREXQUANT INVESTMENT LP	0.39%	111.78K	3.42M	-87.46K	-43.90%
Sep 30, 2025	FEDERATED HERMES, INC.	0.67%	193.33K	5.92M	185.05K	+2,236.56%
Sep 30, 2025	CITIGROUP INC	0.24%	70.53K	2.16M	-975.95K	-93.26%
Jun 30, 2025	UBS GROUP AG	4.42%	1.27M	28.25M	782.23K	+159.55%
Jun 30, 2025	VANGUARD GROUP INC	5.34%	1.54M	34.13M	20.23K	+1.33%
Jun 30, 2025	FISHER ASSET MANAGEMENT, LLC	0.2%	58.9K	1.31M	21	+0.04%
Jun 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.04%	10.8K	239.65K	10.8K	+100.00%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	3.74%	1.08M	23.9M	-67.16K	-5.87%
Jun 30, 2025	SQUAREPOINT OPS LLC	0.38%	109.39K	2.43M	109.39K	+100.00%
Jun 30, 2025	CAMBER CAPITAL MANAGEMENT LP	0.43%	125K	2.78M	-625K	-83.33%
Jun 30, 2025	GRANAHAN INVESTMENT MANAGEMENT, LLC	0.46%	131.66K	2.92M	-14.84K	-10.13%
Jun 30, 2025	HIGHMARK WEALTH MANAGEMENT LLC	0.51%	145.55K	3.23M	53.55K	+58.21%
Jun 30, 2025	ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	0.52%	150.81K	3.35M	150.81K	+100.00%
Jun 30, 2025	SANOFI	2.85%	821.92K	18.25M	0	0
Jun 30, 2025	TANG CAPITAL MANAGEMENT LLC	4.62%	1.33M	29.55M	-214.27K	-13.87%
Jun 30, 2025	BLACKROCK, INC.	6.2%	1.79M	39.67M	-389.66K	-17.90%
Jun 30, 2025	MOODY ALDRICH PARTNERS LLC	0.21%	60.09K	1.33M	-23.13K	-27.79%
Jun 30, 2025	AQUATIC CAPITAL MANAGEMENT LLC	0.23%	65.81K	1.46M	65.81K	+100.00%
Jun 30, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.25%	73.01K	1.62M	-23.97K	-24.72%
Jun 30, 2025	NUVEEN, LLC	1.12%	323.53K	7.18M	267.52K	+477.62%
Jun 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.28%	80.21K	1.78M	4.19K	+5.51%
Jun 30, 2025	INVESCO LTD.	0.29%	83.17K	1.85M	61.84K	+289.83%
Jun 30, 2025	SECTORAL ASSET MANAGEMENT INC	0.29%	83.9K	1.86M	83.9K	+100.00%
Jun 30, 2025	BALYASNY ASSET MANAGEMENT L.P.	0.32%	92.85K	2.06M	60.78K	+189.49%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.34%	97.1K	2.16M	-40K	-29.18%
Jun 30, 2025	GSA CAPITAL PARTNERS LLP	0.24%	69.8K	1.55M	69.8K	+100.00%
Jun 30, 2025	FMR LLC	0.25%	72.12K	1.6B	-1.83M	-96.21%
Jun 30, 2025	TWO SIGMA INVESTMENTS, LP	0.8%	231.37K	5.14M	-34.49K	-12.97%
Jun 30, 2025	STATE STREET CORP	2.85%	821.03K	18.23M	-39.69K	-4.61%
Jun 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.91%	263.09K	5.84M	-75.61K	-22.32%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.97%	279.84K	6.21M	-742	-0.26%
Jun 30, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	1.11%	321.04K	7.13M	218.99K	+214.58%
Jun 30, 2025		1.12%	323.53K	7.18M	267.52K	+477.62%
Jun 30, 2025	FRANKLIN RESOURCES INC	1.23%	354.51K	7.87M	117	+0.03%
Jun 30, 2025	JACOBS LEVY EQUITY MANAGEMENT, INC	1.28%	368.45K	8.18M	351.96K	+2,134.77%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.61%	463.36K	10.29M	-27.81K	-5.66%
Jun 30, 2025	683 CAPITAL MANAGEMENT, LLC	1.74%	500K	11.1M	304.37K	+155.59%
Jun 30, 2025	WOODLINE PARTNERS LP	1.74%	501.02K	11.12M	-290K	-36.66%
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	2.34%	673.17K	14.95M	-241.91K	-26.44%
Jun 30, 2025	PALO ALTO INVESTORS LP	2.82%	812.82K	18.04M	-207.89K	-20.37%
Jun 30, 2025	MORGAN STANLEY	6.49%	1.87M	41.51M	1.37M	+270.53%
Jun 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	8.59%	2.47M	54.94M	106.5K	+4.50%
Jun 30, 2025	SOFINNOVA INVESTMENTS, INC.	3.58%	1.03M	22.92M	-127.67K	-11.01%
Jun 30, 2025	FIRST LIGHT ASSET MANAGEMENT, LLC	12.29%	3.54M	78.58M	-1.09M	-23.61%
Jun 30, 2025	ECOR1 CAPITAL, LLC	27.35%	7.88M	174.94M	0	0
Jun 30, 2025	CORTON CAPITAL INC.	0.04%	12K	266.49K	1.31K	+12.20%
Jun 30, 2025	CRESSET ASSET MANAGEMENT, LLC	0.05%	13.17K	292.26K	-1.45K	-9.91%
Jun 30, 2025	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0.05%	14.22K	315.62M	-373	-2.56%
Jun 30, 2025	EXOME ASSET MANAGEMENT LLC	0.05%	15K	333K	-101.62K	-87.14%
Jun 30, 2025	LOS ANGELES CAPITAL MANAGEMENT LLC	0.05%	15.03K	333.6K	15.03K	+100.00%
Jun 30, 2025	NEBULA RESEARCH & DEVELOPMENT LLC	0.05%	15.53K	344.83K	28	+0.18%
Jun 30, 2025	MACQUARIE GROUP LTD	0.33%	93.73K	2.08M	0	0
Jun 30, 2025	BARCLAYS PLC	0.35%	100K	2.22M	43.78K	+77.87%
Jun 30, 2025	D. E. SHAW & CO., INC.	0.39%	112.35K	2.49M	-17.31K	-13.35%
Jun 30, 2025	CITADEL ADVISORS LLC	0.41%	118.29K	2.63M	-254.28K	-68.25%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.55%	157.14K	3.49M	3.78K	+2.46%
Jun 30, 2025	NORTHERN TRUST CORP	0.68%	196.26K	4.36M	-16.62K	-7.81%
Jun 30, 2025	ENSIGN PEAK ADVISORS, INC	0.75%	215.45K	4.78M	0	0
Jun 30, 2025	JPMORGAN CHASE & CO	0.86%	247.63K	5.5M	233.33K	+1,631.64%
Jun 30, 2025	IKARIAN CAPITAL, LLC	0.05%	15.66K	347.7K	15.66K	+100.00%
Jun 30, 2025	ALPS ADVISORS INC	0.06%	15.86K	352.16K	-7.26K	-31.41%
Jun 30, 2025	TREXQUANT INVESTMENT LP	0.69%	199.24K	4.42M	45.68K	+29.75%
Jun 30, 2025	MILLENNIUM MANAGEMENT LLC	0.71%	203.54K	4.52M	185.74K	+1,043.04%
Jun 30, 2025	TWO SIGMA ADVISERS, LP	1.01%	290.4K	6.45M	22.3K	+8.32%
Jun 30, 2025	VICTORY CAPITAL MANAGEMENT INC	1.85%	532.09K	11.81M	125.66K	+30.92%
Jun 30, 2025	CITIGROUP INC	3.63%	1.05M	23.23M	-24.76K	-2.31%
Jun 30, 2025	ASSENAGON ASSET MANAGEMENT S.A.	0.06%	16.96K	376.49K	-225.53K	-93.01%
Jun 30, 2025	BREVAN HOWARD CAPITAL MANAGEMENT LP	0.08%	22.95K	509.56K	8.76K	+61.73%
Jun 30, 2025	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.08%	23.76K	527K	1.81K	+8.26%
Jun 30, 2025	ENGINEERS GATE MANAGER LP	0.09%	24.75K	549.34K	24.75K	+100.00%
Jun 30, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.09%	26.83K	595.6K	-4.35K	-13.95%
Jun 30, 2025	AQR CAPITAL MANAGEMENT LLC	0.1%	27.72K	615.43M	-2.29K	-7.63%
Jun 30, 2025	ALLIANCEBERNSTEIN L.P.	0.11%	30.52K	677.54M	0	0
Jun 30, 2025	XTX TOPCO LTD	0.11%	30.64K	680.25K	30.64K	+100.00%
Jun 30, 2025	SUSQUEHANNA PORTFOLIO STRATEGIES, LLC	0.11%	32.8K	728.23K	32.8K	+100.00%
Jun 30, 2025	SKANDINAVISKA ENSKILDA BANKEN AB (PUBL)	0.12%	33.52K	744.21K	0	0
Jun 30, 2025	SAVANT CAPITAL, LLC	0.04%	10.87K	241.29K	10.87K	+100.00%
Jun 30, 2025	NEOS INVESTMENT MANAGEMENT LLC	0.04%	11.4K	253.17K	11.4K	+100.00%
Jun 30, 2025	BLEAKLEY FINANCIAL GROUP, LLC	0.13%	37.55K	833.63K	37.55K	+100.00%
Jun 30, 2025	UBS OCONNOR LLC	0.13%	38.53K	855.32K	-8.52K	-18.11%
Jun 30, 2025	PDT PARTNERS, LLC	0.15%	44.47K	987.12K	-64	-0.14%
Jun 30, 2025	DCF ADVISERS, LLC	0.17%	48K	1.07M	13.15K	+37.73%
Mar 31, 2025	CAMBER CAPITAL MANAGEMENT LP	2.45%	750K	13.94M	-500K	-40.00%
Mar 31, 2025	NORTHERN TRUST CORP	0.69%	212.89K	3.96M	-7.1K	-3.23%
Mar 31, 2025	TREXQUANT INVESTMENT LP	0.5%	153.56K	2.85M	92.84K	+152.90%
Mar 31, 2025	ECOR1 CAPITAL, LLC	25.72%	7.88M	146.49M	6.65K	+0.08%
Mar 31, 2025	FMR LLC	6.22%	1.91M	35.42M	-1.13M	-37.13%
Mar 31, 2025	SANOFI	2.68%	821.92K	15.28M	0	0
Mar 31, 2025	WOODLINE PARTNERS LP	2.58%	791.02K	14.71M	305.95K	+63.07%
Mar 31, 2025	MORGAN STANLEY	1.65%	504.64K	9.38M	288.72K	+133.72%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.6%	491.17K	9.13M	4.57K	+0.94%
Mar 31, 2025	UBS GROUP AG	1.6%	490.27K	9.11M	453.67K	+1,239.32%
Mar 31, 2025	VICTORY CAPITAL MANAGEMENT INC	1.33%	406.43K	7.56M	71.98K	+21.52%
Mar 31, 2025	FIRST LIGHT ASSET MANAGEMENT, LLC	15.12%	4.63M	86.14M	3.76M	+433.28%
Mar 31, 2025	CITADEL ADVISORS LLC	1.22%	372.57K	6.93M	198.84K	+114.46%
Mar 31, 2025	683 CAPITAL MANAGEMENT, LLC	0.64%	195.63K	3.64M	195.63K	+100.00%
Mar 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.25%	76.02K	1.41M	9.55K	+14.37%
Mar 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.23%	70.8K	1.32M	-222.9K	-75.89%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	3.73%	1.14M	21.27M	1.13M	+6,273.39%
Mar 31, 2025	CITIGROUP INC	3.5%	1.07M	19.91M	1.02M	+1,892.02%
Mar 31, 2025	PALO ALTO INVESTORS LP	3.33%	1.02M	18.98M	176.74K	+20.94%
Mar 31, 2025	5AM VENTURE MANAGEMENT, LLC	1.17%	357.73K	6.65M	0	0
Mar 31, 2025	FRANKLIN RESOURCES INC	1.16%	354.39K	6.59M	21	+0.01%
Mar 31, 2025	RENAISSANCE TECHNOLOGIES LLC	1.11%	338.7K	6.3M	145.5K	+75.31%
Mar 31, 2025	POINT72 ASSET MANAGEMENT, L.P.	7.73%	2.37M	44.03M	2.37M	+100.00%
Mar 31, 2025	BLACKROCK, INC.	7.1%	2.18M	40.46M	-371.87K	-14.59%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.92%	280.58K	5.22M	-138.53K	-33.05%
Mar 31, 2025	TWO SIGMA ADVISERS, LP	0.87%	268.1K	4.98M	-25.2K	-8.59%
Mar 31, 2025	BANK OF NEW YORK MELLON CORP	0.2%	61.21K	1.14M	4.04K	+7.06%
Mar 31, 2025	TANG CAPITAL MANAGEMENT LLC	5.04%	1.55M	28.72M	214.27K	+16.10%
Mar 31, 2025	VANGUARD GROUP INC	4.95%	1.52M	28.21M	-326.42K	-17.70%
Mar 31, 2025	SOFINNOVA INVESTMENTS, INC.	3.79%	1.16M	21.57M	1.03M	+772.68%
Mar 31, 2025	TWO SIGMA INVESTMENTS, LP	0.87%	265.86K	4.94M	-86.18K	-24.48%
Mar 31, 2025	OPALEYE MANAGEMENT INC.	0.82%	250.93K	4.66M	250.93K	+100.00%
Mar 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	2.99%	915.08K	17.01M	-9.93K	-1.07%
Mar 31, 2025	STATE STREET CORP	2.81%	860.72K	16M	-425.03K	-33.06%
Mar 31, 2025	MACQUARIE GROUP LTD	0.31%	93.73K	1.74M	0	0
Mar 31, 2025	D. E. SHAW & CO., INC.	0.42%	129.65K	2.41M	-67.45K	-34.22%
Mar 31, 2025		0.32%	96.8K	1.8M	-118.2K	-54.98%
Mar 31, 2025	EXOME ASSET MANAGEMENT LLC	0.38%	116.62K	2.17M	116.62K	+100.00%
Mar 31, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	0.33%	102.05K	1.9M	-311.95K	-75.35%
Mar 31, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.32%	96.97K	1.8M	96.97K	+100.00%
Mar 31, 2025	MARSHALL WACE, LLP	0.3%	92.87K	1.73M	92.87K	+100.00%
Mar 31, 2025	HIGHMARK WEALTH MANAGEMENT LLC	0.3%	92K	1.71M	92K	+100.00%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.5%	153.36K	2.85M	-12.7K	-7.65%
Mar 31, 2025	GRANAHAN INVESTMENT MANAGEMENT, LLC	0.48%	146.49K	2.72M	40.41K	+38.10%
Mar 31, 2025	MOODY ALDRICH PARTNERS LLC	0.27%	83.22K	1.55M	83.22K	+100.00%
Mar 31, 2025	ASSENAGON ASSET MANAGEMENT S.A.	0.79%	242.49K	4.51M	-89.27K	-26.91%
Mar 31, 2025	ENSIGN PEAK ADVISORS, INC	0.7%	215.45K	4.01M	0	0
Mar 31, 2024	CITADEL ADVISORS LLC	1.21%	324.75K	7.31M	209.77K	+182.45%
Mar 31, 2024	CITIGROUP INC	0.29%	79.04K	1.78M	75.42K	+2,083.51%
Mar 31, 2024	UBS OCONNOR LLC	0.31%	83.03K	1.87M	-4.1K	-4.70%
Mar 31, 2024	RAFFERTY ASSET MANAGEMENT, LLC	0.34%	90.69K	2.04M	90.69K	+100.00%
Mar 31, 2024	MORGAN STANLEY	2.36%	636.11K	14.33M	34.08K	+5.66%
Mar 31, 2024	SATURN V CAPITAL MANAGEMENT LLC	2.18%	586.03K	13.2M	-78.25K	-11.78%
Mar 31, 2024	DIMENSIONAL FUND ADVISORS LP	1.75%	469.86K	10.58M	-128.03K	-21.41%
Mar 31, 2024	NORTHERN TRUST CORP	0.75%	201.15K	4.53M	-6K	-2.90%
Mar 31, 2024	D. E. SHAW & CO., INC.	0.69%	186.8K	4.21M	26.48K	+16.52%
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	0.64%	171.69K	3.87M	-60.07K	-25.92%
Mar 31, 2024	OCTAGON CAPITAL ADVISORS LP	0.61%	165K	3.72M	45K	+37.50%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.56%	150.43K	3.39M	10.93K	+7.84%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.54%	146.27K	3.29M	1.45K	+1.00%
Mar 31, 2024	FMR LLC	0.52%	140.75K	3.17M	-61.97K	-30.57%
Mar 31, 2024	HUDSON BAY CAPITAL MANAGEMENT LP	0.49%	132.5K	2.98M	37.5K	+39.47%
Mar 31, 2024	TWO SIGMA ADVISERS, LP	0.49%	131.7K	2.97M	32.5K	+32.76%
Mar 31, 2024	TWO SIGMA INVESTMENTS, LP	0.45%	119.97K	2.7M	32.44K	+37.06%
Mar 31, 2024	RENAISSANCE TECHNOLOGIES LLC	0.37%	100.2K	2.26M	4.6K	+4.81%
Mar 31, 2024	MACQUARIE GROUP LTD	0.35%	93.73K	2.11M	0	0
Mar 31, 2024	JACOBS LEVY EQUITY MANAGEMENT, INC	0.18%	49.39K	1.11M	13.76K	+38.64%
Mar 31, 2024	ASSENAGON ASSET MANAGEMENT S.A.	0.82%	221.84K	5M	0	0
Mar 31, 2024	MILLENNIUM MANAGEMENT LLC	2.4%	647.13K	14.57M	240.09K	+58.99%
Mar 31, 2024	MANGROVE PARTNERS	2.56%	689.52K	15.53M	689.52K	+100.00%
Mar 31, 2024	VANGUARD GROUP INC	5.03%	1.35M	30.49M	-26.11K	-1.89%
Mar 31, 2024	BLACKROCK INC.	6.39%	1.72M	38.74M	-79.77K	-4.43%
Mar 31, 2024	SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC	0.2%	54.21K	1.22M	54.21K	+100.00%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.2%	54.53K	1.23M	29.11K	+114.54%
Mar 31, 2024	WELLINGTON MANAGEMENT GROUP LLP	0.22%	59.05K	1.33M	59.05K	+100.00%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.24%	64.09K	1.44M	-5.95K	-8.49%
Mar 31, 2024	UBS GROUP AG	0.24%	64.17K	1.45M	45.42K	+242.36%
Mar 31, 2024	STEMPOINT CAPITAL LP	1%	269.55K	6.07M	224.55K	+499.00%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.24%	64.24K	1.45M	11.13K	+20.95%
Mar 31, 2024	BLACKSTONE INC.	1.22%	328.72K	7.4M	0	0
Mar 31, 2024	PLATINUM INVESTMENT MANAGEMENT LTD	0.25%	66.15K	1.49M	66.15K	+100.00%
Mar 31, 2024	FISHER ASSET MANAGEMENT, LLC	0.26%	70.65K	1.59M	-500	-0.70%
Mar 31, 2024	5AM VENTURE MANAGEMENT, LLC	1.33%	357.73K	8.06M	0	0
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	1.57%	421.7K	9.5M	1.6K	+0.38%
Mar 31, 2024	EVENTIDE ASSET MANAGEMENT, LLC	1.59%	427K	9.62M	0	0
Mar 31, 2024	FRANKLIN RESOURCES INC	1.73%	465.37K	10.48M	60.26K	+14.87%
Mar 31, 2024	WOODLINE PARTNERS LP	1.89%	508.84K	11.46M	-686.14K	-57.42%
Mar 31, 2024	DEEP TRACK CAPITAL, LP	1.97%	529.45K	11.92M	-1.51M	-74.01%
Mar 31, 2024	PALO ALTO INVESTORS LP	2.97%	799.91K	18.01M	113.02K	+16.45%
Mar 31, 2024	POINT72 ASSET MANAGEMENT, L.P.	3.21%	864.1K	19.46M	75.56K	+9.58%
Mar 31, 2024	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	3.34%	899.7K	20.26M	0	0
Mar 31, 2024	FIRST LIGHT ASSET MANAGEMENT, LLC	3.51%	944.11K	21.26M	-293.07K	-23.69%
Mar 31, 2024	GREAT POINT PARTNERS LLC	3.63%	976.98K	22M	0	0
Mar 31, 2024	STATE STREET CORP	4.48%	1.21M	27.19M	763.06K	+171.73%
Mar 31, 2024	BOXER CAPITAL, LLC	4.83%	1.3M	29.28M	0	0
Mar 31, 2024	TANG CAPITAL MANAGEMENT LLC	4.94%	1.33M	29.97M	-619.73K	-31.77%
Mar 31, 2024	ECOR1 CAPITAL, LLC	27.93%	7.52M	169.37M	0	0
Mar 31, 2024	NEW YORK STATE COMMON RETIREMENT FUND	0.03%	7.91K	178K	-11	-0.14%
Mar 31, 2024	RUSSELL INVESTMENTS GROUP, LTD.	0.03%	8.15K	183.47K	-390	-4.57%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.03%	8.96K	201.78K	8.96K	+100.00%
Mar 31, 2024	ALGERT GLOBAL LLC	0.03%	9.1K	205K	9.1K	+100.00%
Mar 31, 2024	AMERICAN INTERNATIONAL GROUP, INC.	0.03%	9.23K	207.91K	-80	-0.86%
Mar 31, 2024	METLIFE INVESTMENT MANAGEMENT, LLC	0.04%	11.04K	248.69K	0	0
Mar 31, 2024	MIRAE ASSET GLOBAL INVESTMENTS CO., LTD.	0.05%	12.13K	265.28K	12.13K	+100.00%
Mar 31, 2024	JPMORGAN CHASE & CO	0.05%	13.37K	301.18K	-4.12K	-23.56%
Mar 31, 2024	VERITION FUND MANAGEMENT LLC	0.05%	13.47K	303.39K	13.47K	+100.00%
Mar 31, 2024	LEGAL & GENERAL GROUP PLC	0.05%	13.8K	310.78M	-2.5K	-15.36%
Mar 31, 2024	PROFUND ADVISORS LLC	0.05%	14.15K	318.57M	14.15K	+100.00%
Mar 31, 2024	XTX TOPCO LTD	0.06%	15.7K	353.65K	5.02K	+47.03%
Mar 31, 2024	BALYASNY ASSET MANAGEMENT L.P.	0.06%	15.75K	354.6K	-3.2K	-16.90%
Mar 31, 2024	CREDIT SUISSE AG/	0.06%	15.81K	356.11K	-5.28K	-25.03%
Mar 31, 2024	BNP PARIBAS ARBITRAGE, SNC	0.06%	16.52K	372.03K	-4.43K	-21.16%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.06%	16.89K	380.45K	-10.34K	-37.97%
Mar 31, 2024	ACADIAN ASSET MANAGEMENT LLC	0.07%	18.67K	420K	18.67K	+100.00%
Mar 31, 2024	ALPS ADVISORS INC	0.07%	18.75K	422.18K	679	+3.76%
Mar 31, 2024	INVESCO LTD.	0.07%	20.08K	452.09K	10.36K	+106.58%
Mar 31, 2024	SWISS NATIONAL BANK	0.08%	21K	472.92K	-5.2K	-19.85%
Mar 31, 2024	TD ASSET MANAGEMENT INC	0.08%	22.6K	508.95M	-8.8K	-28.03%
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	0.11%	28.53K	642.5K	-2.06K	-6.73%
Mar 31, 2024	QUBE RESEARCH & TECHNOLOGIES LTD	0.11%	28.54K	642.77K	25.9K	+981.55%
Mar 31, 2024	MARTINGALE ASSET MANAGEMENT L P	0.11%	28.64K	644.86K	16	+0.06%
Mar 31, 2024	RHUMBLINE ADVISERS	0.11%	29.19K	657.34K	-203	-0.69%
Mar 31, 2024	TREXQUANT INVESTMENT LP	0.12%	32.52K	732.28K	10.69K	+48.94%
Mar 31, 2024	FEDERATED HERMES, INC.	0.13%	36.04K	811.64K	14	+0.04%
Mar 31, 2024	VICTORY CAPITAL MANAGEMENT INC	0.14%	36.68K	826.03K	-6.46K	-14.97%
Mar 31, 2024	ENSIGN PEAK ADVISORS, INC	0.16%	43.44K	978.31K	0	0
Dec 31, 2023	DEEP TRACK CAPITAL, LP	7.67%	2.04M	43.63M	691.18K	+51.36%
Dec 31, 2023	ALLIANCEBERNSTEIN L.P.	0.12%	30.59K	655.24K	0	0
Dec 31, 2023	TD ASSET MANAGEMENT INC	0.12%	31.4K	672.59K	0	0
Dec 31, 2023	ECOR1 CAPITAL, LLC	28.33%	7.52M	161.1M	0	0
Dec 31, 2023	MARSHALL WACE, LLP	0.13%	33.36K	714.51K	-1.52K	-4.36%
Dec 31, 2023	JACOBS LEVY EQUITY MANAGEMENT, INC	0.13%	35.63K	763.09K	-171.16K	-82.77%
Dec 31, 2023	FEDERATED HERMES, INC.	0.14%	36.03K	771.7K	0	0
Dec 31, 2023	VICTORY CAPITAL MANAGEMENT INC	0.16%	43.14K	924.06K	-550	-1.26%
Dec 31, 2023	ENSIGN PEAK ADVISORS, INC	0.16%	43.44K	930.53K	0	0
Dec 31, 2023		0.17%	45K	963.9K	45K	+100.00%
Dec 31, 2023	NUVEEN ASSET MANAGEMENT, LLC	0.2%	53.11K	1.14M	-19.45K	-26.81%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.26%	70.04K	1.5M	631	+0.91%
Dec 31, 2023	FISHER ASSET MANAGEMENT, LLC	0.27%	71.15K	1.52M	500	+0.71%
Dec 31, 2023	HRT FINANCIAL LP	0.28%	75.63K	1.62M	75.63K	+100.00%
Dec 31, 2023	UBS OCONNOR LLC	0.33%	87.12K	1.87M	-37.34K	-30.00%
Dec 31, 2023	TWO SIGMA INVESTMENTS, LP	0.33%	87.53K	1.87M	-20.09K	-18.67%
Dec 31, 2023	MACQUARIE GROUP LTD	0.35%	93.73K	2.01M	0	0
Dec 31, 2023	HUDSON BAY CAPITAL MANAGEMENT LP	0.36%	95K	2.03M	-5K	-5.00%
Dec 31, 2023	RENAISSANCE TECHNOLOGIES LLC	0.36%	95.6K	2.05M	2.9K	+3.13%
Dec 31, 2023	TWO SIGMA ADVISERS, LP	0.37%	99.2K	2.12M	-17.9K	-15.29%
Dec 31, 2023	CITADEL ADVISORS LLC	0.43%	114.97K	2.46M	-71.5K	-38.34%
Dec 31, 2023	OCTAGON CAPITAL ADVISORS LP	0.45%	120K	2.57M	120K	+100.00%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.53%	139.5K	2.99M	-38.9K	-21.80%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.55%	144.82K	3.1M	1.81K	+1.26%
Dec 31, 2023	D. E. SHAW & CO., INC.	0.6%	160.33K	3.43M	14.43K	+9.89%
Dec 31, 2023	FMR LLC	0.76%	202.71K	4.34M	-64.9K	-24.25%
Dec 31, 2023	NORTHERN TRUST CORP	0.78%	207.15K	4.44M	6.97K	+3.48%
Dec 31, 2023	ASSENAGON ASSET MANAGEMENT S.A.	0.84%	221.84K	4.75M	0	0
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	0.87%	231.75K	4.97M	5.47K	+2.42%
Dec 31, 2023	BLACKSTONE INC.	1.24%	328.72K	7.04M	0	0
Dec 31, 2023	SUVRETTA CAPITAL MANAGEMENT, LLC	1.34%	354.87K	7.6M	-124.57K	-25.98%
Dec 31, 2023	5AM VENTURE MANAGEMENT, LLC	1.35%	357.73K	7.66M	0	0
Dec 31, 2023	FRANKLIN RESOURCES INC	1.53%	405.12K	8.68M	75.03K	+22.73%
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	1.53%	407.03K	8.72M	-39.19K	-8.78%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.58%	420.11K	9M	20.51K	+5.13%
Dec 31, 2023	EVENTIDE ASSET MANAGEMENT, LLC	1.61%	427K	9.15M	0	0
Dec 31, 2023	STATE STREET CORP	1.67%	444.35K	9.52M	-489.02K	-52.39%
Dec 31, 2023	DIMENSIONAL FUND ADVISORS LP	2.25%	597.89K	12.81M	-88.57K	-12.90%
Dec 31, 2023	MORGAN STANLEY	2.27%	602.03K	12.9M	521.05K	+643.37%
Dec 31, 2023	SATURN V CAPITAL MANAGEMENT LLC	2.5%	664.28K	14.23M	87.18K	+15.11%
Dec 31, 2023	PALO ALTO INVESTORS LP	2.59%	686.88K	14.71M	255.66K	+59.29%
Dec 31, 2023	POINT72 ASSET MANAGEMENT, L.P.	2.97%	788.55K	16.89M	-2.66K	-0.34%
Dec 31, 2023	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	3.39%	899.7K	19.27M	0	0
Dec 31, 2023	GREAT POINT PARTNERS LLC	3.68%	976.98K	20.93M	82.65K	+9.24%
Dec 31, 2023	WOODLINE PARTNERS LP	4.5%	1.19M	25.6M	354.15K	+42.12%
Dec 31, 2023	FIRST LIGHT ASSET MANAGEMENT, LLC	4.66%	1.24M	26.5M	446.37K	+56.45%
Dec 31, 2023	BOXER CAPITAL, LLC	4.9%	1.3M	27.85M	0	0
Dec 31, 2023	VANGUARD GROUP INC	5.2%	1.38M	29.56M	-322.67K	-18.95%
Dec 31, 2023	BLACKROCK INC.	6.78%	1.8M	38.55M	-24.07K	-1.32%
Dec 31, 2023	TANG CAPITAL MANAGEMENT LLC	7.35%	1.95M	41.78M	0	0
Sep 30, 2023	RAFFERTY ASSET MANAGEMENT, LLC	0.23%	62.34K	-	-30.31K	-32.72%
Sep 30, 2023	FISHER ASSET MANAGEMENT, LLC	0.27%	70.65K	-	0	0
Sep 30, 2023	NUVEEN ASSET MANAGEMENT, LLC	0.27%	72.57K	-	159	+0.22%
Sep 30, 2023	MORGAN STANLEY	0.3%	80.99K	-	9.37K	+13.08%
Sep 30, 2023	HUDSON BAY CAPITAL MANAGEMENT LP	0.38%	100K	-	50K	+100.00%
Sep 30, 2023	BAKER BROS. ADVISORS LP	0.4%	106.2K	-	-669.73K	-86.31%
Sep 30, 2023	TWO SIGMA INVESTMENTS, LP	0.4%	107.62K	-	-38.52K	-26.36%
Sep 30, 2023	TWO SIGMA ADVISERS, LP	0.44%	117.1K	-	-8.9K	-7.06%
Sep 30, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.54%	143.01K	-	3.4K	+2.43%
Sep 30, 2023	D. E. SHAW & CO., INC.	0.55%	145.89K	-	-59.9K	-29.11%
Sep 30, 2023	GOLDMAN SACHS GROUP INC	0.67%	178.4K	-	46.37K	+35.12%
Sep 30, 2023	NORTHERN TRUST CORP	0.75%	200.18K	-	-2.39K	-1.18%
Sep 30, 2023	JACOBS LEVY EQUITY MANAGEMENT, INC	0.78%	206.79K	-	8.06K	+4.06%
Sep 30, 2023	ASSENAGON ASSET MANAGEMENT S.A.	0.83%	221.84K	-	-273.22K	-55.19%
Sep 30, 2023	FMR LLC	1%	267.62K	-	-25.95K	-8.84%
Sep 30, 2023	BLACKSTONE INC.	1.23%	328.72K	-	0	0
Sep 30, 2023	FRANKLIN RESOURCES INC	1.24%	330.09K	-	330.09K	+100.00%
Sep 30, 2023	5AM VENTURE MANAGEMENT, LLC	1.34%	357.73K	-	0	0
Sep 30, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.5%	399.59K	-	3.57K	+0.90%
Sep 30, 2023	EVENTIDE ASSET MANAGEMENT, LLC	1.6%	427K	-	427K	+100.00%
Sep 30, 2023	SATURN V CAPITAL MANAGEMENT LLC	2.17%	577.1K	-	577.1K	+100.00%
Sep 30, 2023	DIMENSIONAL FUND ADVISORS LP	2.58%	686.46K	-	-218.45K	-24.14%
Sep 30, 2023	POINT72 ASSET MANAGEMENT, L.P.	2.97%	791.2K	-	-668.71K	-45.80%
Sep 30, 2023	WOODLINE PARTNERS LP	3.16%	840.82K	-	-193.73K	-18.73%
Sep 30, 2023	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	3.38%	899.7K	-	0	0
Sep 30, 2023	BLACKROCK INC.	6.85%	1.82M	-	-813	-0.04%
Sep 30, 2023	UBS GROUP AG	0.07%	17.59K	-	-17.61K	-50.04%
Sep 30, 2023	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.07%	18.49K	-	18.49K	+100.00%
Sep 30, 2023	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0.07%	19.37K	-	-4.15K	-17.65%
Sep 30, 2023	ALPS ADVISORS INC	0.07%	19.57K	-	104	+0.53%
Sep 30, 2023	PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO	0.09%	23.14K	-	0	0
Sep 30, 2023	CREDIT SUISSE AG/	0.09%	23.49K	-	-2.46K	-9.49%
Sep 30, 2023	BNP PARIBAS ARBITRAGE, SNC	0.09%	23.8K	-	4.37K	+22.47%
Sep 30, 2023	ECOR1 CAPITAL, LLC	28.24%	7.52M	-	0	0
Sep 30, 2023	CAPTION MANAGEMENT, LLC	0.09%	25K	-	-2K	-7.41%
Sep 30, 2023	JANE STREET GROUP, LLC	0.1%	25.67K	-	25.67K	+100.00%
Sep 30, 2023	RHUMBLINE ADVISERS	0.11%	30.2K	-	-191	-0.63%
Sep 30, 2023	ALLIANCEBERNSTEIN L.P.	0.11%	30.59K	-	-1.93K	-5.93%
Sep 30, 2023	TD ASSET MANAGEMENT INC	0.12%	31.4K	-	31.4K	+100.00%
Sep 30, 2023	CITIGROUP INC	0.13%	35.13K	-	1.33K	+3.95%
Sep 30, 2023	FEDERATED HERMES, INC.	0.14%	36.03K	-	-17	-0.05%
Sep 30, 2023	BARCLAYS PLC	0.14%	36.07K	-	-12.59K	-25.88%
Sep 30, 2023	SWISS NATIONAL BANK	0.14%	37.9K	-	-4.7K	-11.03%
Sep 30, 2023	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.15%	40.54K	-	-48.05K	-54.24%
Sep 30, 2023	ENSIGN PEAK ADVISORS, INC	0.16%	43.44K	-	0	0
Sep 30, 2023	VICTORY CAPITAL MANAGEMENT INC	0.16%	43.69K	-	43.69K	+100.00%
Sep 30, 2023	AMERIPRISE FINANCIAL INC	0.17%	44.92K	-	-42.95K	-48.88%
Sep 30, 2023	BANK OF NEW YORK MELLON CORP	0.26%	69.41K	-	24	+0.03%

Insiders

Insiders	Designation	Shares Held
ECOR1 CAPITAL, LLC		7.88M
NODELMAN OLEG		7.52M
NOVO A/S	10 percent owner	3.03M
NOVO HOLDINGS A/S	10 percent owner	1.94M
FAGA DANIEL	President, CEO	466.79K
FRAZIER HEALTHCARE VII, L.P.	10 percent owner	311.29K
TOPPER JAMES N		297.8K
LYDON NICHOLAS	director	271.11K
FRAZIER HEALTHCARE V, LP	10 percent owner	88.71K
SURIA HAMZA	President, CEO	68.6K
LIZZUL PAUL F.	Chief Medical Officer	37.21K
LONDEI MARCO	Chief Medical Officer	22.38K
MULROY DENNIS	CHIEF FINANCIAL OFFICER	17.67K
WARE J. ANTHONY	director	9.63K
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	9.16K
RENTON HOLLINGS	director	4.97K
FENTON DENNIS M	director	4.97K
AVALON VENTURES VII L P	10 percent owner	0
PISCITELLI DOMINIC	Chief Financial Officer	0

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Jan 07, 2026	LOUMEAU ERIC J	SALE	47.23	500	23.62K	9.16K
Jan 07, 2026	MULROY DENNIS	SALE	45.11	1.91K	86.07K	17.67K
Jan 07, 2026	FAGA DANIEL	SALE	45.11	9.2K	415.1K	466.79K
Jan 07, 2026	LIZZUL PAUL F.	SALE	45.11	2.24K	100.82K	37.21K
Jan 05, 2026	FAGA DANIEL	SALE	43.26	15.31K	662.27K	458.14K
Jan 05, 2026	LOUMEAU ERIC J	SALE	43.26	2.98K	129.04K	13.25K
Jan 05, 2026	MULROY DENNIS	SALE	43.26	3.36K	145.48K	14.33K
Jan 05, 2026	LIZZUL PAUL F.	SALE	43.26	4.22K	182.51K	33.3K
Dec 23, 2025	WARE J. ANTHONY	SALE	49.58	3.9K	193.34K	9.63K
Dec 22, 2025	LOUMEAU ERIC J	SALE	51.00	10K	510K	8.95K
Dec 22, 2025	LIZZUL PAUL F.	SALE	50.00	1.5K	75K	26.97K
Dec 22, 2025	MULROY DENNIS	SALE	50.00	10K	500K	9.4K
Dec 18, 2025	LOUMEAU ERIC J	SALE	46.99	141	6.63K	8.95K
Dec 17, 2025	LOUMEAU ERIC J	SALE	46.00	10K	460K	9.09K
Dec 16, 2025	MULROY DENNIS	SALE	45.21	6.36K	287.51K	9.4K
Dec 16, 2025	LOUMEAU ERIC J	SALE	45.24	4.2K	189.77K	9.09K
Sep 30, 2025	LOUMEAU ERIC J	SALE	29.00	8.24K	238.96K	9.09K
Aug 08, 2025	RENTON HOLLINGS	SALE	19.70	7.12K	140.26K	4.97K
Jul 02, 2025	RENTON HOLLINGS	SALE	23.82	13.68K	325.78K	4.97K
Jun 18, 2025	RENTON HOLLINGS	SALE	23.97	3.02K	72.27K	4.97K
Jun 18, 2025	FENTON DENNIS M	SALE	23.97	3.02K	72.27K	4.97K
Jan 02, 2025	ECOR1 CAPITAL, LLC	PURCHASE	12.95	6.65K	86.07K	7.88M
Dec 31, 2024	ECOR1 CAPITAL, LLC	PURCHASE	12.93	13.27K	171.51K	7.87M
Dec 30, 2024	ECOR1 CAPITAL, LLC	PURCHASE	12.92	65.18K	842.06K	7.86M
Nov 29, 2024	RENTON HOLLINGS	SALE	25.00	10K	250K	1.95K
Sep 23, 2024	LIZZUL PAUL F.	SALE	38.67	1.5K	58.01K	15.4K
Sep 17, 2024	LOUMEAU ERIC J	SALE	38.41	3.78K	145.19K	3.24K
Sep 16, 2024	MULROY DENNIS	SALE	40.13	10K	401.3K	4.74K
Sep 16, 2024	LOUMEAU ERIC J	SALE	40.13	6.5K	260.85K	7.02K
Sep 16, 2024	LIZZUL PAUL F.	SALE	38.93	2.22K	86.42K	15.4K
Aug 14, 2024	ECOR1 CAPITAL, LLC	PURCHASE	36.50	273.97K	10M	7.79M
Aug 14, 2024	LIZZUL PAUL F.	SALE	40.00	2K	80K	11.62K
Jul 18, 2024	LIZZUL PAUL F.	SALE	35.00	1.5K	52.5K	11.62K
Jul 15, 2024	RENTON HOLLINGS	SALE	30.98	2.9K	89.75K	1.95K
Jun 21, 2024	FENTON DENNIS M	SALE	23.17	1.95K	45.18K	1.95K
Jun 18, 2024	RENTON HOLLINGS	SALE	23.16	1.95K	45.16K	1.95K
May 22, 2024	MULROY DENNIS	SALE	23.72	1.5K	35.58K	964
Mar 25, 2024	FAGA DANIEL	SALE	21.42	3K	64.27K	749.09K
Mar 22, 2024	FAGA DANIEL	SALE	22.78	145.94K	3.33M	752.09K
Feb 16, 2024	LOUMEAU ERIC J	SALE	25.00	5K	125K	3.24K
Jan 30, 2024	MULROY DENNIS	SALE	23.63	3.07K	72.43K	964
Jan 08, 2024	FAGA DANIEL	SALE	21.81	6.87K	149.75K	898.03K
Jan 08, 2024	MULROY DENNIS	SALE	21.81	2.18K	47.55K	4.03K
Jan 08, 2024	LIZZUL PAUL F.	SALE	21.81	2.55K	55.7K	10.12K
Jan 08, 2024	LOUMEAU ERIC J	SALE	21.81	2.31K	50.27K	3.24K
Nov 22, 2023	LOUMEAU ERIC J	SALE	14.19	882	12.52K	0
Sep 18, 2023	MULROY DENNIS	SALE	19.32	3.9K	75.24K	964
Sep 18, 2023	LOUMEAU ERIC J	SALE	19.32	3.9K	75.23K	882
Sep 14, 2023	LIZZUL PAUL F.	SALE	19.48	2.11K	41.01K	6.53K
Sep 14, 2023	LOUMEAU ERIC J	SALE	19.48	2.11K	41.01K	4.78K
Sep 14, 2023	MULROY DENNIS	SALE	19.48	2.11K	41.01K	4.86K
Aug 08, 2022	LOUMEAU ERIC J	SALE	25.00	523	13.08K	0
Jun 08, 2022	LOUMEAU ERIC J	SALE	24.00	2.5K	60K	523
May 18, 2022	LOUMEAU ERIC J	SALE	20.50	1.15K	23.49K	523
May 05, 2022	ECOR1 CAPITAL, LLC	SALE	21.63	668.24K	14.45M	7.52M
May 05, 2022	NODELMAN OLEG	PURCHASE	21.63	668.24K	14.45M	7.52M
Dec 20, 2021	SURIA HAMZA	SALE	36.40	5.52K	201.03K	68.6K
Nov 05, 2021	SURIA HAMZA	SALE	35.00	14.3K	500.57K	67.64K
Nov 04, 2021	LOUMEAU ERIC J	SALE	35.00	5K	175K	0
Nov 01, 2021	SURIA HAMZA	SALE	32.88	2.56K	84.14K	67.64K
Oct 26, 2021	SURIA HAMZA	SALE	30.00	15.99K	479.79K	67.64K
May 04, 2021	ECOR1 CAPITAL, LLC	PURCHASE	23.25	165K	3.84M	7.52M
May 03, 2021	ECOR1 CAPITAL, LLC	PURCHASE	23.31	20.8K	484.87K	7.36M
Apr 30, 2021	ECOR1 CAPITAL, LLC	PURCHASE	23.16	35.7K	826.82K	7.33M
Apr 27, 2021	ECOR1 CAPITAL, LLC	PURCHASE	23.82	33.8K	805.09K	7.3M
Apr 26, 2021	ECOR1 CAPITAL, LLC	PURCHASE	23.80	13.9K	330.86K	7.27M
Apr 23, 2021	ECOR1 CAPITAL, LLC	PURCHASE	23.54	99.6K	2.34M	7.25M
Mar 09, 2021	ECOR1 CAPITAL, LLC	PURCHASE	18.70	531K	9.93M	7.15M
Mar 08, 2021	ECOR1 CAPITAL, LLC	PURCHASE	18.97	2.78M	52.69M	6.62M
Feb 23, 2021	ECOR1 CAPITAL, LLC	PURCHASE	25.48	29.5K	751.66K	3.84M
Feb 12, 2021	LOUMEAU ERIC J	SALE	35.00	10K	350K	0
Dec 10, 2019	WARE J. ANTHONY	PURCHASE	14.05	3.6K	50.58K	3.6K
Jun 10, 2019	SURIA HAMZA	SALE	76.31	454	34.64K	17.64K
Jun 04, 2019	LONDEI MARCO	SALE	74.50	2K	149.22K	22.38K
Jan 15, 2019	LONDEI MARCO	SALE	70.04	14.89K	1.04M	22.38K
Jan 14, 2019	SURIA HAMZA	SALE	71.10	12.24K	870.3K	30.06K
Dec 17, 2018	LONDEI MARCO	SALE	68.47	6.74K	461.58K	144.88K
Dec 14, 2018	SURIA HAMZA	SALE	70.51	7.8K	549.98K	30.06K
Dec 12, 2018	SURIA HAMZA	SALE	72.88	8.32K	606.62K	30.06K
Dec 11, 2018	SURIA HAMZA	SALE	70.83	5K	354.01K	30.06K
Dec 10, 2018	SURIA HAMZA	SALE	72.48	4.96K	359.81K	35.06K
Dec 03, 2018	PISCITELLI DOMINIC	SALE	75.81	1.1K	83.39K	0
Apr 16, 2018	LYDON NICHOLAS	SALE	90.26	2.22K	200.55K	271.11K
Aug 21, 2017	NOVO HOLDINGS A/S	SALE	21.10	356.3K	7.52M	1.94M
Aug 15, 2017	NOVO HOLDINGS A/S	SALE	21.00	143.43K	3.01M	2.29M
Aug 14, 2017	NOVO HOLDINGS A/S	SALE	21.79	35.17K	766.49K	2.44M
Aug 07, 2017	NOVO HOLDINGS A/S	SALE	22.92	1.02K	23.44K	2.47M
Aug 04, 2017	NOVO HOLDINGS A/S	SALE	22.00	10.27K	225.96K	2.95M
Aug 03, 2017	NOVO HOLDINGS A/S	SALE	22.01	21.45K	472.19K	2.96M
Aug 02, 2017	NOVO HOLDINGS A/S	SALE	23.87	25.7K	613.48K	2.98M
Aug 01, 2017	NOVO HOLDINGS A/S	SALE	23.87	23.56K	562.27K	3.01M
Jul 26, 2017	AVALON VENTURES VII L P	SALE	24.35	37.04K	901.92K	0
Jan 31, 2017	FRAZIER HEALTHCARE VII, L.P.	PURCHASE	15.00	311.29K	4.67M	311.29K
Jan 31, 2017	LYDON NICHOLAS	PURCHASE	15.00	16.67K	249.99K	287.62K
Jan 31, 2017	TOPPER JAMES N	PURCHASE	15.00	88.71K	1.33M	297.8K
Jan 31, 2017	NOVO A/S	PURCHASE	15.00	50K	750K	3.03M
Jan 31, 2017	FRAZIER HEALTHCARE V, LP	PURCHASE	15.00	88.71K	1.33M	88.71K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES101.18K18

NET SHARES-101.18K18

SHARES HELD1.16M18

% NET SHARES-108.76%0%

ANAB Stock Ownership Breakdown

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Stock Outstanding Shares

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Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

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Stock Outstanding Shares

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Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions