How many institutions own AGIO stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own AGIO shares is 308, representing 104.65% of the company's common stock.

Who are the major shareholders selling Agios Pharmaceuticals, Inc. stock?

D. E. SHAW & CO., INC., in the last quarter, reduced its stake in AGIO by -38.32% restricting it's holding to 367.75 thousand shares of worth nearly $14.76M. ARMISTICE CAPITAL, LLC also lessened -34.59% of the AGIO shares from its portfolio, reducing its holding to 764 thousand shares of worth $30.67M. ALPS ADVISORS INC also shunned AGIO shares holding by -11.89% last quarter which brought its holding to 27.55 thousand shares worth $1.11M.

Investors who are buying AGIO stock?

As per its latest 13F filing, PARADIGM BIOCAPITAL ADVISORS LP increased its stake in AGIO by 134.01% in the last quarter. The institutional holder raised its holding to 2.67 million shares having worth more than $107.32M. CAPTION MANAGEMENT, LLC also added 138.05% more shares of AGIO to its portfolio, raising its holding to 386.6 thousand shares of worth $15.52M. ARROWMARK COLORADO HOLDINGS LLC also increased its AGIO shares holding by 3.22% which brought its holding to 679.92 thousand shares worth $27.29M.

AGIO's major insiders: who are they?

The insider with the most stakes in AGIO is CELGENE CORP /DE/ , 10 percent owner at the company. Additionally, AGIO stock is highly held by director FOUSE JACQUALYN A and Chief Executive Officer Goff Brian among others.

Did an insider recently sell AGIO stock?

Company executives, directors, and other insiders own 1.68% percent of Agios Pharmaceuticals, Inc.'s stock. Within the last six months, there have been 15 transaction(s) in which AGIO insiders have sold stock, totaling 46.03K shares. Insiders that have sold shares include MILANOVA TSVETA, GHEUENS SARAH, and GOFF BRIAN.

Which insider recently purchased AGIO stock?

There have been 0 transaction(s) during the past 6-months in which Agios Pharmaceuticals, Inc. insiders have bought stock, totalling 0 shares

How much of AGIO does insiders own?

Around 624.8K Agios Pharmaceuticals, Inc. shares are held by insiders, which represents about 1.68% of AGIO stock.

Who is the insider with the largest stake?

AGIO 10 percent owner, CELGENE CORP /DE/ holds the largest portfolio of the company's shares. AGIO shares owned by CELGENE total nearly 1.78 million.

Which institution holds the most shares in AGIO?

PARADIGM BIOCAPITAL ADVISORS LP is the largest institutional owner in AGIO which holds 2.67 million shares worth $107.32M or 4.61% of the total AGIO shares outstanding followed by D. E. SHAW & CO., INC. with ownership of 367.75 thousand shares representing 0.63% of the AGIO ownership. CAPTION MANAGEMENT, LLC is the third largest stakeholder with 386.6 thousand shares or 0.67% of the ownership worth more than $15.52M.

Is Agios Pharmaceuticals, Inc. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the AGIO is concerned, it is a stock which is optionable.

Is there a short position on AGIO's shares?

Number of AGIO shares short is 7.45M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding AGIO shares are there?

As of today, 58.31M shares of AGIO are outstanding.

Is there many float in AGIO stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, AGIO has 51.51M shares in float.

AGIO short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for AGIO is 5.03.

Agios Pharmaceuticals (AGIO) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares12.77

Short Percent Of Float12.87

Shares Outstanding58.31M

Shares Float51.51M

Shares Short7.45M

Short Ratio5.03

12.87%

Short % of Float

12.77%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

1.68% Percentage of Shares held by All Insiders

104.65% Percentage of Shares held by All Institutions

106.44% Percentage of Float held by Institutions

308

Number of Institutions Holding Shares

Institutional Ownership

About 104.65% of AGIO shares are held by financial institutions. PARADIGM BIOCAPITAL ADVISORS LP is the top corporate investor, holding 2.67M shares valued at $107.32M. A 4.61% stake in Agios Pharmaceuticals, Inc. is owned by the company. D. E. SHAW & CO., INC. owns 367.75K shares valued at $14.76M, which translates its holding of 0.63% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Sep 30, 2025	PARADIGM BIOCAPITAL ADVISORS LP	4.61%	2.67M	107.32M	1.53M	+134.01%
Sep 30, 2025	D. E. SHAW & CO., INC.	0.63%	367.75K	14.76M	-228.45K	-38.32%
Sep 30, 2025	CAPTION MANAGEMENT, LLC	0.67%	386.6K	15.52M	224.2K	+138.05%
Sep 30, 2025	ARROWMARK COLORADO HOLDINGS LLC	1.17%	679.92K	27.29M	21.23K	+3.22%
Sep 30, 2025	ARMISTICE CAPITAL, LLC	1.32%	764K	30.67M	-404K	-34.59%
Sep 30, 2025	ALPS ADVISORS INC	0.05%	27.55K	1.11M	-3.72K	-11.89%
Sep 30, 2025	SG AMERICAS SECURITIES, LLC	0.05%	27.65K	1.11M	27.65K	+100.00%
Sep 30, 2025	VICTORY CAPITAL MANAGEMENT INC	0.05%	30.23K	1.21M	818	+2.78%
Sep 30, 2025	SEI INVESTMENTS CO	0.06%	32.3K	1.3M	21.97K	+212.80%
Sep 30, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.06%	34.03K	1.37M	0	0
Sep 30, 2025	HARBOR CAPITAL ADVISORS, INC.	0.06%	34.84K	1.4M	-2.19K	-5.91%
Sep 30, 2025	EDGEWOOD MANAGEMENT LLC	0.06%	35K	1.4M	0	0
Sep 30, 2025	DEKABANK DEUTSCHE GIROZENTRALE	0.07%	40K	1.56M	0	0
Sep 30, 2025	VIRGINIA RETIREMENT SYSTEMS ET AL	0.07%	41.06K	1.65M	-8.6K	-17.32%
Sep 30, 2025	CITIGROUP INC	0.08%	43.62K	1.75M	-12.87K	-22.78%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0.08%	44.75K	1.8M	7.06K	+18.73%
Sep 30, 2025	PHOCAS FINANCIAL CORP.	0.08%	46.61K	1.87M	46.61K	+100.00%
Sep 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.09%	49.79K	2M	10.7K	+27.36%
Sep 30, 2025	ASSENAGON ASSET MANAGEMENT S.A.	0.12%	67.15K	2.7M	67.15K	+100.00%
Sep 30, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.12%	68.22K	2.74M	18.82K	+38.09%
Sep 30, 2025	UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH	0.12%	71.21K	2.86M	15.93K	+28.81%
Sep 30, 2025	FIRST TRUST ADVISORS LP	0.13%	74.43K	2.99M	38K	+104.32%
Sep 30, 2025	RHUMBLINE ADVISERS	0.15%	87.7K	3.52M	-2.18K	-2.42%
Sep 30, 2025	JUMP FINANCIAL, LLC	0.15%	87.9K	3.53M	87.9K	+100.00%
Sep 30, 2025	PRUDENTIAL FINANCIAL INC	0.17%	98.24K	3.94M	-60.12K	-37.96%
Sep 30, 2025	SWISS NATIONAL BANK	0.18%	106.66K	4.28M	-2.8K	-2.56%
Sep 30, 2025	NUVEEN, LLC	0.21%	119.58K	4.8M	0	0
Sep 30, 2025	HUDSON BAY CAPITAL MANAGEMENT LP	0.21%	122.5K	4.92M	-7.5K	-5.77%
Sep 30, 2025	INVESCO LTD.	0.22%	126.98K	5.1M	14.36K	+12.75%
Sep 30, 2025	TD ASSET MANAGEMENT INC	0.22%	128.29K	5.15M	-39.9K	-23.72%
Sep 30, 2025	PATIENT SQUARE CAPITAL LP	0.23%	133.83K	5.37M	-5.91K	-4.23%
Sep 30, 2025	AMERICAN CENTURY COMPANIES INC	0.25%	145.12K	5.83M	17.47K	+13.69%
Sep 30, 2025	ALLIANZ ASSET MANAGEMENT GMBH	0.25%	146.64K	5.89M	7.75K	+5.58%
Sep 30, 2025	PEREGRINE CAPITAL MANAGEMENT LLC	0.28%	162.91K	6.54M	162.91K	+100.00%
Sep 30, 2025	JPMORGAN CHASE & CO	0.32%	183.1K	7.35M	-844.32K	-82.18%
Sep 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	1.38%	800K	32.11M	9K	+1.14%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	1.39%	804.77K	32.3M	156.71K	+24.18%
Sep 30, 2025	GW&K INVESTMENT MANAGEMENT, LLC	1.47%	852.94K	34.24M	-15.68K	-1.80%
Sep 30, 2025	PALO ALTO INVESTORS LP	0.46%	265.5K	10.66M	-3.29K	-1.22%
Sep 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.46%	267.3K	10.73M	207.3K	+345.50%
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.47%	270.1K	10.84M	3.44K	+1.29%
Sep 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.47%	272.16K	10.69M	-22.58K	-7.66%
Sep 30, 2025	IKARIAN CAPITAL, LLC	0.26%	150K	6.02M	150K	+100.00%
Sep 30, 2025	JANE STREET GROUP, LLC	0.68%	395.12K	15.86M	361.63K	+1,079.85%
Sep 30, 2025	DEUTSCHE BANK AG\	1.6%	926.73K	37.2M	5.15K	+0.56%
Sep 30, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	1.65%	958.54K	38.48M	-31.2K	-3.15%
Sep 30, 2025	CALIGAN PARTNERS LP	1.68%	975K	39.14M	975K	+100.00%
Sep 30, 2025	ERSTE ASSET MANAGEMENT GMBH	4.77%	2.76M	108.58M	438.41K	+18.84%
Sep 30, 2025	AXA INVESTMENT MANAGERS S.A.	0.31%	177.68K	7.13M	177.68K	+100.00%
Sep 30, 2025	DIMENSIONAL FUND ADVISORS LP	1.76%	1.02M	40.99M	-84.89K	-7.67%
Sep 30, 2025	BAKER BROS. ADVISORS LP	0.33%	189.87K	7.62M	0	0
Sep 30, 2025	HIGHVISTA STRATEGIES LLC	0.34%	195.3K	7.84M	125.17K	+178.49%
Sep 30, 2025	BARCLAYS PLC	0.37%	216.04K	8.67M	35.34K	+19.55%
Sep 30, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	2.21%	1.28M	51.37M	0	0
Sep 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	2.86%	1.66M	66.51M	-617.31K	-27.14%
Sep 30, 2025	STATE STREET CORP	3.91%	2.26M	90.83M	311.6K	+15.97%
Sep 30, 2025	COMMODORE CAPITAL LP	4.04%	2.34M	93.86M	13.29K	+0.57%
Sep 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	4.27%	2.47M	99.2M	2.05M	+485.46%
Sep 30, 2025	BELLEVUE GROUP AG	6.41%	3.71M	149.11M	124.59K	+3.47%
Sep 30, 2025	VANGUARD GROUP INC	9.67%	5.6M	224.98M	-77.14K	-1.36%
Sep 30, 2025	EAGLE HEALTH INVESTMENTS LP	0.43%	246.23K	9.88M	-84.6K	-25.57%
Sep 30, 2025	NORTHERN TRUST CORP	0.96%	555.41K	22.29M	-1.4K	-0.25%
Sep 30, 2025	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	1.7%	987.34K	39.63M	-29.55K	-2.91%
Sep 30, 2025	FARALLON CAPITAL MANAGEMENT LLC	9.98%	5.78M	232.05M	13.6K	+0.24%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	1.95%	1.13M	45.36M	9.69K	+0.87%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.44%	1.42M	56.86M	10.56K	+0.75%
Sep 30, 2025	MARSHALL WACE, LLP	0.39%	226.82K	9.1M	-457.85K	-66.87%
Sep 30, 2025	SUMMITTX CAPITAL, L.P.	0.45%	262.98K	10.56M	262.98K	+100.00%
Sep 30, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.5%	290.9K	11.68M	290.9K	+100.00%
Sep 30, 2025	LEGAL & GENERAL GROUP PLC	0.56%	322.93K	12.96M	258.63K	+402.19%
Sep 30, 2025	FISHER ASSET MANAGEMENT, LLC	1.5%	870.15K	34.93M	-7.4K	-0.84%
Sep 30, 2025	TCG CROSSOVER MANAGEMENT, LLC	2.47%	1.43M	57.4M	733.04K	+105.17%
Sep 30, 2025	MACQUARIE GROUP LTD	3.38%	1.96M	78.6M	57.51K	+3.03%
Sep 30, 2025	DIADEMA PARTNERS LP	0.38%	222.1K	8.92M	100K	+81.90%
Sep 30, 2025	BLACKROCK, INC.	7.85%	4.55M	182.47M	-288.02K	-5.96%
Sep 30, 2025	UBS GROUP AG	0.42%	242.81K	9.75M	123.98K	+104.33%
Sep 30, 2025	ARTISAN PARTNERS LIMITED PARTNERSHIP	0.7%	402.94K	16.17M	12.96K	+3.32%
Sep 30, 2025	MORGAN STANLEY	0.72%	417K	16.74M	125.03K	+42.82%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.83%	482.19K	19.35M	6.15K	+1.29%
Sep 30, 2025	CITADEL ADVISORS LLC	0.85%	491.98K	19.75M	-589.49K	-54.51%
Sep 30, 2025	BALYASNY ASSET MANAGEMENT L.P.	0.86%	495.49K	19.89M	495.49K	+100.00%
Sep 30, 2025	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.92%	530.1K	21.28M	24.87K	+4.92%
Sep 30, 2025	SCS CAPITAL MANAGEMENT LLC	1.03%	598.77K	24.03M	-5.32K	-0.88%
Jun 30, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	2.21%	1.28M	42.56M	209.9K	+19.62%
Jun 30, 2025	FARALLON CAPITAL MANAGEMENT LLC	9.96%	5.77M	191.83M	67K	+1.18%
Jun 30, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.77%	447.02K	14.87M	185.8K	+71.13%
Jun 30, 2025	SCS CAPITAL MANAGEMENT LLC	1.04%	604.09K	20.09M	-7.01K	-1.15%
Jun 30, 2025	MARSHALL WACE, LLP	1.18%	684.67K	22.77M	163.8K	+31.45%
Jun 30, 2025	TCG CROSSOVER MANAGEMENT, LLC	1.2%	697K	23.18M	697K	+100.00%
Jun 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	1.37%	791K	26.31M	48K	+6.46%
Jun 30, 2025	CALIGAN PARTNERS LP	1.85%	1.07M	35.63M	369.98K	+52.76%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.43%	1.41M	46.76M	11.17K	+0.80%
Jun 30, 2025	MACQUARIE GROUP LTD	3.28%	1.9M	63.21M	50.05K	+2.70%
Jun 30, 2025	STATE STREET CORP	3.37%	1.95M	64.89M	-498.37K	-20.35%
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	3.93%	2.27M	75.64M	-27.1K	-1.18%
Jun 30, 2025	ERSTE ASSET MANAGEMENT GMBH	4.02%	2.33M	77.4M	96.59K	+4.33%
Jun 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.51%	294.74K	9.86M	-16.04K	-5.16%
Jun 30, 2025	MILLENNIUM MANAGEMENT LLC	0.52%	300.2K	9.98M	247.13K	+465.64%
Jun 30, 2025	EAGLE HEALTH INVESTMENTS LP	0.57%	330.83K	11M	0	0
Jun 30, 2025	ARTISAN PARTNERS LIMITED PARTNERSHIP	0.67%	389.98K	12.97M	-20.69K	-5.04%
Jun 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.73%	422.13K	14.04M	397.67K	+1,625.65%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.82%	476.04K	15.83M	11.08K	+2.38%
Jun 30, 2025	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.87%	505.23K	16.8M	118.7K	+30.71%
Jun 30, 2025	NORTHERN TRUST CORP	0.96%	556.81K	18.52M	-19.45K	-3.38%
Jun 30, 2025	ORBIMED ADVISORS LLC	0.96%	557.9K	18.56M	232.4K	+71.40%
Jun 30, 2025	ARROWMARK COLORADO HOLDINGS LLC	1.14%	658.69K	21.91M	-168.93K	-20.41%
Jun 30, 2025	GW&K INVESTMENT MANAGEMENT, LLC	1.5%	868.62K	28.89M	51.09K	+6.25%
Jun 30, 2025	PRUDENTIAL FINANCIAL INC	0.27%	158.36K	5.27M	-45.88K	-22.47%
Jun 30, 2025	CAPTION MANAGEMENT, LLC	0.28%	162.4K	5.4M	46.4K	+40.00%
Jun 30, 2025	TD ASSET MANAGEMENT INC	0.29%	168.19K	5.59M	-9.88K	-5.55%
Jun 30, 2025	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.32%	187.4K	6.23M	-144.25K	-43.49%
Jun 30, 2025	BAKER BROS. ADVISORS LP	0.33%	189.87K	6.31M	189.87K	+100.00%
Jun 30, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.38%	217.4K	7.23M	70.13K	+47.62%
Jun 30, 2025	NORDEA INVESTMENT MANAGEMENT AB	0.39%	224.75K	7.52M	573	+0.26%
Jun 30, 2025	AXA S.A.	0.39%	225.37K	7.5M	248	+0.11%
Jun 30, 2025	WOODLINE PARTNERS LP	0.4%	233.07K	7.75M	212.69K	+1,043.56%
Jun 30, 2025	CENTERBOOK PARTNERS LP	0.42%	243.06K	8.08M	134.55K	+124.00%
Jun 30, 2025	BANK OF NEW YORK MELLON CORP	0.46%	266.65K	8.87M	3.2K	+1.22%
Jun 30, 2025	PALO ALTO INVESTORS LP	0.46%	268.78K	8.94M	-7.8K	-2.82%
Jun 30, 2025	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	1.76%	1.02M	33.82M	-8.83K	-0.86%
Jun 30, 2025	JPMORGAN CHASE & CO	1.77%	1.03M	34.17M	-21.94K	-2.09%
Jun 30, 2025	DIMENSIONAL FUND ADVISORS LP	1.91%	1.11M	36.79M	-155.98K	-12.36%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	1.93%	1.12M	37.26M	-15.28K	-1.35%
Jun 30, 2025	PARADIGM BIOCAPITAL ADVISORS LP	1.97%	1.14M	38M	1.14M	+100.00%
Jun 30, 2025	BARCLAYS PLC	0.31%	180.7K	6.01M	67.55K	+59.70%
Jun 30, 2025	FISHER ASSET MANAGEMENT, LLC	1.51%	877.54K	29.19M	-81.8K	-8.53%
Jun 30, 2025	DEUTSCHE BANK AG\	1.59%	921.59K	30.65M	-7.38K	-0.79%
Jun 30, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	1.71%	989.75K	32.92M	647.57K	+189.25%
Jun 30, 2025	ARMISTICE CAPITAL, LLC	2.02%	1.17M	38.85M	-880K	-42.97%
Jun 30, 2025	COMMODORE CAPITAL LP	4.01%	2.33M	77.33M	140K	+6.41%
Jun 30, 2025		4.02%	2.33M	77.4M	96.59K	+4.33%
Jun 30, 2025	BLACKROCK, INC.	8.34%	4.83M	160.77M	-274.99K	-5.38%
Jun 30, 2025	VANGUARD GROUP INC	9.81%	5.68M	188.98M	77.43K	+1.38%
Jun 30, 2025	MORGAN STANLEY	0.5%	291.97K	9.71B	-2.66K	-0.90%
Jun 30, 2025	D. E. SHAW & CO., INC.	1.03%	596.2K	19.83B	41.38K	+7.46%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	1.12%	648.06K	21.55B	-10.59K	-1.61%
Jun 30, 2025	CITADEL ADVISORS LLC	1.87%	1.08M	35.97B	217.97K	+25.24%
Jun 30, 2025	BELLEVUE GROUP AG	6.2%	3.59M	119.41M	75K	+2.13%
Mar 31, 2025	WALLEYE CAPITAL LLC	0.26%	150.51K	4.41M	-49.03K	-24.57%
Mar 31, 2025	ARTISAN PARTNERS LIMITED PARTNERSHIP	0.71%	410.67K	12.03M	-88.46K	-17.72%
Mar 31, 2025	BELLEVUE GROUP AG	6.12%	3.52M	102.99M	0	0
Mar 31, 2025	PRUDENTIAL FINANCIAL INC	0.36%	204.24K	5.98M	99.32K	+94.66%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	1.15%	658.65K	19.3M	91.48K	+16.13%
Mar 31, 2025	SCS CAPITAL MANAGEMENT LLC	1.06%	611.1K	17.91M	611.1K	+100.00%
Mar 31, 2025	D. E. SHAW & CO., INC.	0.97%	554.82K	16.26M	38.35K	+7.42%
Mar 31, 2025	MARSHALL WACE, LLP	0.91%	520.87K	15.26M	-110.76K	-17.53%
Mar 31, 2025	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.58%	331.64K	9.72M	131.16K	+65.42%
Mar 31, 2025	EAGLE HEALTH INVESTMENTS LP	0.58%	330.83K	9.69M	0	0
Mar 31, 2025	ORBIMED ADVISORS LLC	0.57%	325.5K	9.54M	298.8K	+1,119.10%
Mar 31, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.54%	310.78K	9.4M	-43.67K	-12.32%
Mar 31, 2025	MORGAN STANLEY	0.51%	294.62K	8.63M	-83.47K	-22.08%
Mar 31, 2025	AXA S.A.	0.39%	225.12K	6.6M	49.74K	+28.36%
Mar 31, 2025	FARALLON CAPITAL MANAGEMENT LLC	9.92%	5.7M	167.02M	26K	+0.46%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.43%	1.39M	40.87M	44.93K	+3.33%
Mar 31, 2025	NORTHERN TRUST CORP	1%	576.26K	16.88M	-19.22K	-3.23%
Mar 31, 2025	TD ASSET MANAGEMENT INC	0.31%	178.07K	5.22M	12.4K	+7.48%
Mar 31, 2025	BLACKROCK, INC.	8.89%	5.11M	149.69M	92.49K	+1.84%
Mar 31, 2025	STATE STREET CORP	4.26%	2.45M	71.77M	297.2K	+13.81%
Mar 31, 2025	ARMISTICE CAPITAL, LLC	3.56%	2.05M	60.01M	-216.3K	-9.55%
Mar 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	4.01%	2.3M	67.43M	-122.18K	-5.04%
Mar 31, 2025	CITIGROUP INC	0.31%	176.13K	5.16M	-17.02K	-8.81%
Mar 31, 2025	DIMENSIONAL FUND ADVISORS LP	2.2%	1.26M	36.98M	-66.99K	-5.04%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	1.98%	1.14M	33.27M	730.69K	+180.46%
Mar 31, 2025	JPMORGAN CHASE & CO	1.83%	1.05M	30.75M	34K	+3.35%
Mar 31, 2025	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	1.79%	1.03M	30.05M	83.53K	+8.87%
Mar 31, 2025	POLAR CAPITAL HOLDINGS PLC	1.74%	1M	29.36M	375K	+59.81%
Mar 31, 2025	CITADEL ADVISORS LLC	1.5%	863.5K	25.3M	-570.18K	-39.77%
Mar 31, 2025	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.67%	386.52K	11.33M	260.85K	+207.55%
Mar 31, 2025	VANGUARD GROUP INC	9.75%	5.6M	164.21M	-26.73K	-0.47%
Mar 31, 2025		3.88%	2.23M	65.44M	220K	+10.95%
Mar 31, 2025	COMMODORE CAPITAL LP	3.8%	2.19M	64.02M	2.19M	+100.00%
Mar 31, 2025	FISHER ASSET MANAGEMENT, LLC	1.67%	959.34K	28.11M	-1.32K	-0.14%
Mar 31, 2025	PALO ALTO INVESTORS LP	0.48%	276.58K	8.1M	276.58K	+100.00%
Mar 31, 2025	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	1.86%	1.07M	31.35M	100	+0.01%
Mar 31, 2025	MACQUARIE GROUP LTD	3.22%	1.85M	54.22M	165.55K	+9.82%
Mar 31, 2025	DEUTSCHE BANK AG\	1.62%	928.97K	27.22M	-6.28K	-0.67%
Mar 31, 2025	ARROWMARK COLORADO HOLDINGS LLC	1.44%	827.62K	24.25M	-89.8K	-9.79%
Mar 31, 2025	GW&K INVESTMENT MANAGEMENT, LLC	1.42%	817.53K	23.95M	134.06K	+19.62%
Mar 31, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	1.29%	743K	21.77M	440K	+145.21%
Mar 31, 2025	CALIGAN PARTNERS LP	1.22%	701.28K	20.55M	75K	+11.98%
Mar 31, 2025	BANK OF NEW YORK MELLON CORP	0.46%	263.45K	7.72M	-2.06K	-0.78%
Mar 31, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.45%	261.22K	7.65M	9.45K	+3.75%
Mar 31, 2025	CASDIN CAPITAL, LLC	0.44%	250K	7.33M	0	0
Mar 31, 2025	CUTTER CAPITAL MANAGEMENT, LP	0.41%	235.35K	6.9M	-66.27K	-21.97%
Mar 31, 2025	NORDEA INVESTMENT MANAGEMENT AB	0.39%	224.17K	6.51M	3.6K	+1.63%
Mar 31, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.26%	147.28K	4.32M	24.44K	+19.90%
Mar 31, 2025	PATIENT SQUARE CAPITAL LP	0.24%	139.73K	4.09M	18K	+14.79%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.81%	464.96K	13.62M	-7.59K	-1.61%
Mar 31, 2024	SECTOR GAMMA AS	0.29%	164.38K	4.81M	164.38K	+100.00%
Mar 31, 2024	PRUDENTIAL FINANCIAL INC	0.35%	194.13K	5.68M	124.6K	+179.20%
Mar 31, 2024	CUTTER CAPITAL MANAGEMENT, LP	0.52%	288.58K	8.44M	288.58K	+100.00%
Mar 31, 2024	VESTAL POINT CAPITAL, LP	0.58%	325K	9.5M	325K	+100.00%
Mar 31, 2024	EAGLE HEALTH INVESTMENTS LP	0.59%	330.83K	9.67M	0	0
Mar 31, 2024	D. E. SHAW & CO., INC.	0.65%	362.13K	10.59M	145.65K	+67.28%
Mar 31, 2024	LAURION CAPITAL MANAGEMENT LP	0.65%	364.76K	10.67M	364.76K	+100.00%
Mar 31, 2024	PARADIGM BIOCAPITAL ADVISORS LP	0.72%	400K	11.7M	400K	+100.00%
Mar 31, 2024	FARALLON CAPITAL MANAGEMENT LLC	10%	5.59M	163.47M	1.42M	+34.14%
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	3.6%	2.01M	58.86M	388.38K	+23.91%
Mar 31, 2024	MACQUARIE GROUP LTD	3.51%	1.96M	57.3M	-55.76K	-2.77%
Mar 31, 2024	ROCK SPRINGS CAPITAL MANAGEMENT LP	3.16%	1.76M	51.59M	-387.67K	-18.01%
Mar 31, 2024	ARROWMARK COLORADO HOLDINGS LLC	2.72%	1.52M	44.42M	-34.72K	-2.23%
Mar 31, 2024	MORGAN STANLEY	2.11%	1.18M	34.51M	686.74K	+139.13%
Mar 31, 2024	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	1.98%	1.11M	32.42M	62.15K	+5.94%
Mar 31, 2024	PICTET ASSET MANAGEMENT HOLDING SA	1.8%	1.01M	29.34M	47.35K	+4.94%
Mar 31, 2024	CITIGROUP INC	0.35%	194.48K	5.69M	87.25K	+81.37%
Mar 31, 2024	RAFFERTY ASSET MANAGEMENT, LLC	0.4%	221.21K	6.47M	67.72K	+44.12%
Mar 31, 2024	AXA S.A.	0.47%	265.37K	7.76M	74	+0.03%
Mar 31, 2024	NORDEA INVESTMENT MANAGEMENT AB	0.48%	266.59K	7.82M	30.76K	+13.05%
Mar 31, 2024	BOOTHBAY FUND MANAGEMENT, LLC	0.48%	268.98K	7.86M	-17.47K	-6.10%
Mar 31, 2024	MARSHALL WACE, LLP	0.5%	278K	8.13M	278K	+100.00%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.97%	539.58K	15.78M	-68.36K	-11.24%
Mar 31, 2024	UBS GROUP AG	0.31%	170.89K	5M	169.03K	+9,117.10%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.35%	195.96K	5.73M	-7.8K	-3.83%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.68%	381.73K	11.16M	175.78K	+85.35%
Mar 31, 2024	CITADEL ADVISORS LLC	1.79%	1M	29.31M	-72.35K	-6.73%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	2.3%	1.28M	37.52M	28.64K	+2.28%
Mar 31, 2024	HUDSON BAY CAPITAL MANAGEMENT LP	0.73%	407.5K	11.92M	-82.5K	-16.84%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.79%	440.23K	12.87M	-16.16K	-3.54%
Mar 31, 2024	ASSENAGON ASSET MANAGEMENT S.A.	0.81%	454.8K	13.3M	404.3K	+800.52%
Mar 31, 2024	CALIGAN PARTNERS LP	0.87%	484.71K	14.17M	42.88K	+9.70%
Mar 31, 2024	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	0.94%	523.17K	15.3M	0	0
Mar 31, 2024	NORTHERN TRUST CORP	1.06%	590.49K	17.27M	-29.75K	-4.80%
Mar 31, 2024	GW&K INVESTMENT MANAGEMENT, LLC	1.16%	649.39K	18.99M	649.39K	+100.00%
Mar 31, 2024	DEUTSCHE BANK AG\	1.19%	667.3K	19.51M	86K	+14.79%
Mar 31, 2024	FISHER ASSET MANAGEMENT, LLC	1.27%	707.34K	20.68M	-4.18K	-0.59%
Mar 31, 2024	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	1.66%	928.6K	27.15M	-1.31K	-0.14%
Mar 31, 2024	JPMORGAN CHASE & CO	4.42%	2.47M	72.3M	-70.06K	-2.76%
Mar 31, 2024	DIMENSIONAL FUND ADVISORS LP	4.61%	2.58M	75.4M	-18.21K	-0.70%
Mar 31, 2024	ARMISTICE CAPITAL, LLC	5.3%	2.96M	86.67M	-560K	-15.89%
Mar 31, 2024	STATE STREET CORP	5.61%	3.14M	91.76M	512.51K	+19.52%
Mar 31, 2024	BELLEVUE GROUP AG	7.17%	4.01M	117.14M	-5K	-0.12%
Mar 31, 2024	BLACKROCK INC.	8.33%	4.66M	136.2M	-304.14K	-6.13%
Mar 31, 2024	VANGUARD GROUP INC	9.97%	5.57M	162.93M	44.58K	+0.81%
Mar 31, 2024	ALPS ADVISORS INC	0.07%	39.64K	1.16M	1.8K	+4.75%
Mar 31, 2024	DEKABANK DEUTSCHE GIROZENTRALE	0.07%	40K	1.15M	0	0
Mar 31, 2024	OAK RIDGE INVESTMENTS LLC	0.07%	40.04K	1.17M	40.04K	+100.00%
Mar 31, 2024	ALGERT GLOBAL LLC	0.08%	42.37K	1.24M	42.37K	+100.00%
Mar 31, 2024	QUBE RESEARCH & TECHNOLOGIES LTD	0.08%	43.24K	1.26M	-74.27K	-63.20%
Mar 31, 2024	ALLEN INVESTMENT MANAGEMENT LLC	0.08%	43.57K	1.27M	7.41K	+20.48%
Mar 31, 2024	MARTINGALE ASSET MANAGEMENT L P	0.08%	45.41K	1.33M	2.1K	+4.84%
Mar 31, 2024	LEGAL & GENERAL GROUP PLC	0.1%	55.49K	1.62B	505	+0.92%
Mar 31, 2024	TREXQUANT INVESTMENT LP	0.11%	60.69K	1.77M	6.15K	+11.27%
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	0.13%	71.22K	2.08M	-2.36K	-3.21%
Mar 31, 2024	INVESCO LTD.	0.14%	76.2K	2.23M	-3.89K	-4.85%
Mar 31, 2024	BALYASNY ASSET MANAGEMENT L.P.	0.14%	78.49K	2.29M	36.49K	+86.86%
Mar 31, 2024	WELLS FARGO & COMPANY/MN	0.12%	66.25K	1.94M	-62.14K	-48.40%
Mar 31, 2024	AMERICAN CENTURY COMPANIES INC	0.14%	80.62K	2.36M	18.26K	+29.29%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.1%	57.4K	1.68M	57.4K	+100.00%
Mar 31, 2024	STATE OF NEW JERSEY COMMON PENSION FUND D	0.15%	84.82K	2.48M	-27.9K	-24.75%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.16%	89.01K	2.6M	39.33K	+79.17%
Mar 31, 2024	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.18%	101.61K	2.97M	498	+0.49%
Mar 31, 2024	RHUMBLINE ADVISERS	0.18%	102.15K	2.99M	1.65K	+1.64%
Mar 31, 2024	SWISS NATIONAL BANK	0.2%	109.86K	3.21M	0	0
Mar 31, 2024	CREDIT SUISSE AG/	0.2%	111.63K	3.26M	2.44K	+2.23%
Mar 31, 2024	ALTITUDE CREST PARTNERS INC.	0.2%	113.1K	3.31M	113.1K	+100.00%
Mar 31, 2024	WALLEYE CAPITAL LLC	0.26%	146.33K	4.28M	-190.14K	-56.51%
Mar 31, 2024	ALLIANZ ASSET MANAGEMENT GMBH	0.27%	150.98K	4.41M	1.87K	+1.26%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.28%	156.11K	4.56M	0	0
Mar 31, 2024	TD ASSET MANAGEMENT INC	0.28%	156.42K	4.57M	64.2K	+69.62%
Mar 31, 2024	KENNEDY CAPITAL MANAGEMENT LLC	0.28%	159.29K	4.66M	159.29K	+100.00%
Dec 31, 2023	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	1.88%	1.05M	23.31M	44.06K	+4.40%
Dec 31, 2023	STATE OF NEW JERSEY COMMON PENSION FUND D	0.2%	112.73K	2.51M	17.95K	+18.94%
Dec 31, 2023	QUBE RESEARCH & TECHNOLOGIES LTD	0.21%	117.51K	2.62M	117.51K	+100.00%
Dec 31, 2023	BNP PARIBAS ARBITRAGE, SNC	0.22%	125.31K	2.79M	66.07K	+111.53%
Dec 31, 2023	UBS OCONNOR LLC	0.23%	126.82K	2.82M	21.6K	+20.53%
Dec 31, 2023	WELLS FARGO & COMPANY/MN	0.21%	118.1K	2.63M	0	0
Dec 31, 2023	VOYA INVESTMENT MANAGEMENT LLC	0.25%	138.16K	3.08M	97.39K	+238.89%
Dec 31, 2023	ALLIANZ ASSET MANAGEMENT GMBH	0.27%	149.11K	3.32M	41.7K	+38.82%
Dec 31, 2023	RAFFERTY ASSET MANAGEMENT, LLC	0.28%	153.49K	3.42M	19.86K	+14.86%
Dec 31, 2023	BARCLAYS PLC	0.28%	154.74K	3.45M	33.73K	+27.87%
Dec 31, 2023	NUVEEN ASSET MANAGEMENT, LLC	0.28%	156.11K	3.48M	1.43K	+0.92%
Dec 31, 2023	MAN GROUP PLC	0.32%	180.43K	4.02M	24.83K	+15.96%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.37%	203.76K	4.54M	-2.11K	-1.03%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.37%	205.95K	4.59M	-68.64K	-25.00%
Dec 31, 2023	D. E. SHAW & CO., INC.	0.39%	216.48K	4.82M	58.2K	+36.77%
Dec 31, 2023	NORDEA INVESTMENT MANAGEMENT AB	0.42%	235.82K	5.28M	-6.15K	-2.54%
Dec 31, 2023	AXA S.A.	0.48%	265.3K	5.91M	-6.42K	-2.36%
Dec 31, 2023	BOOTHBAY FUND MANAGEMENT, LLC	0.51%	286.45K	6.38M	286.45K	+100.00%
Dec 31, 2023	NORGES BANK	0.55%	306.53K	6.83M	306.53K	+100.00%
Dec 31, 2023	EAGLE HEALTH INVESTMENTS LP	0.59%	330.83K	7.37M	63.2K	+23.61%
Dec 31, 2023	WALLEYE CAPITAL LLC	0.6%	336.46K	7.49M	336.46K	+100.00%
Dec 31, 2023	SUVRETTA CAPITAL MANAGEMENT, LLC	0.72%	399.45K	8.9M	-54.55K	-12.02%
Dec 31, 2023	CALIGAN PARTNERS LP	0.79%	441.83K	9.84M	437K	+9,042.00%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.82%	456.39K	10.16M	4.7K	+1.04%
Dec 31, 2023	HUDSON BAY CAPITAL MANAGEMENT LP	0.88%	490K	10.91M	220K	+81.48%
Dec 31, 2023	MORGAN STANLEY	0.88%	493.59K	10.99M	119.46K	+31.93%
Dec 31, 2023	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	0.94%	523.17K	11.65M	231.16K	+79.17%
Dec 31, 2023	DEUTSCHE BANK AG\	1.04%	581.3K	12.95M	-302	-0.05%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	1.09%	607.94K	13.54M	-197.5K	-24.52%
Dec 31, 2023	NORTHERN TRUST CORP	1.11%	620.24K	13.81M	7.5K	+1.22%
Dec 31, 2023	FISHER ASSET MANAGEMENT, LLC	1.28%	711.52K	15.85M	-105.9K	-12.96%
Dec 31, 2023	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	1.67%	929.91K	20.71M	-145	-0.02%
Dec 31, 2023		1.72%	958.28K	21.34M	67.6K	+7.59%
Dec 31, 2023	DEEP TRACK CAPITAL, LP	1.9%	1.06M	23.67M	640.63K	+151.72%
Dec 31, 2023	CITADEL ADVISORS LLC	1.93%	1.07M	23.94M	658.19K	+157.99%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	2.25%	1.25M	27.94M	55.32K	+4.61%
Dec 31, 2023	ARROWMARK COLORADO HOLDINGS LLC	2.78%	1.55M	34.6M	-19.48K	-1.24%
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	2.91%	1.62M	36.18M	-1.5K	-0.09%
Dec 31, 2023	FIRST TRUST ADVISORS LP	3.26%	1.82M	40.5M	43.48K	+2.45%
Dec 31, 2023	MACQUARIE GROUP LTD	3.61%	2.02M	44.88M	23.39K	+1.17%
Dec 31, 2023	ROCK SPRINGS CAPITAL MANAGEMENT LP	3.86%	2.15M	47.93M	-557.89K	-20.59%
Dec 31, 2023	JPMORGAN CHASE & CO	4.56%	2.54M	56.63M	74.93K	+3.04%
Dec 31, 2023	DIMENSIONAL FUND ADVISORS LP	4.65%	2.6M	57.83M	137.87K	+5.61%
Dec 31, 2023	STATE STREET CORP	4.71%	2.63M	58.47M	361.85K	+15.98%
Dec 31, 2023	ARMISTICE CAPITAL, LLC	6.32%	3.52M	78.48M	200K	+6.02%
Dec 31, 2023	BELLEVUE GROUP AG	7.19%	4.01M	89.32M	-2.5K	-0.06%
Dec 31, 2023	FARALLON CAPITAL MANAGEMENT LLC	7.47%	4.17M	92.81M	1.42M	+51.50%
Dec 31, 2023	BLACKROCK INC.	8.89%	4.96M	110.51M	311.23K	+6.69%
Dec 31, 2023	VANGUARD GROUP INC	9.91%	5.53M	123.1M	59.85K	+1.09%
Sep 30, 2023	BELLEVUE GROUP AG	7.22%	4.01M	-	0	0
Sep 30, 2023	ARMISTICE CAPITAL, LLC	5.98%	3.32M	-	68K	+2.09%
Sep 30, 2023	ROCK SPRINGS CAPITAL MANAGEMENT LP	4.87%	2.71M	-	23.89K	+0.89%
Sep 30, 2023	BLACKROCK INC.	8.36%	4.65M	-	-75.26K	-1.59%
Sep 30, 2023	DIMENSIONAL FUND ADVISORS LP	4.42%	2.46M	-	195.07K	+8.62%
Sep 30, 2023	FIRST TRUST ADVISORS LP	3.19%	1.78M	-	-385.41K	-17.84%
Sep 30, 2023	GEODE CAPITAL MANAGEMENT, LLC	2.16%	1.2M	-	41.29K	+3.57%
Sep 30, 2023	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	1.8%	1M	-	74.14K	+7.99%
Sep 30, 2023		1.6%	890.68K	-	890.68K	+100.00%
Sep 30, 2023	FISHER ASSET MANAGEMENT, LLC	1.47%	817.42K	-	-53.68K	-6.16%
Sep 30, 2023	GOLDMAN SACHS GROUP INC	1.45%	805.44K	-	5.83K	+0.73%
Sep 30, 2023	NORTHERN TRUST CORP	1.1%	612.74K	-	-96.97K	-13.66%
Sep 30, 2023	DEUTSCHE BANK AG\	1.05%	581.6K	-	3.63K	+0.63%
Sep 30, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.81%	451.7K	-	14.42K	+3.30%
Sep 30, 2023	MORGAN STANLEY	0.67%	374.13K	-	-17.34K	-4.43%
Sep 30, 2023	FRAZIER LIFE SCIENCES MANAGEMENT, L.P.	0.53%	292K	-	292K	+100.00%
Sep 30, 2023	HUDSON BAY CAPITAL MANAGEMENT LP	0.49%	270K	-	10K	+3.85%
Sep 30, 2023	EAGLE HEALTH INVESTMENTS LP	0.48%	267.63K	-	0	0
Sep 30, 2023	BALYASNY ASSET MANAGEMENT L.P.	0.48%	265.04K	-	46.94K	+21.52%
Sep 30, 2023	AMERIPRISE FINANCIAL INC	0.47%	261.11K	-	-64.12K	-19.71%
Sep 30, 2023	NORDEA INVESTMENT MANAGEMENT AB	0.44%	241.97K	-	-5.37K	-2.17%
Sep 30, 2023	BANK OF NEW YORK MELLON CORP	0.37%	205.88K	-	-4.07K	-1.94%
Sep 30, 2023	INVESCO LTD.	0.37%	204.45K	-	128.75K	+170.08%
Sep 30, 2023	D. E. SHAW & CO., INC.	0.28%	158.28K	-	62.42K	+65.12%
Sep 30, 2023	MAN GROUP PLC	0.28%	155.6K	-	-15.03K	-8.81%
Sep 30, 2023	NUVEEN ASSET MANAGEMENT, LLC	0.28%	154.68K	-	-1.36K	-0.87%
Sep 30, 2023	RAFFERTY ASSET MANAGEMENT, LLC	0.24%	133.62K	-	-29.98K	-18.33%
Sep 30, 2023	WELLS FARGO & COMPANY/MN	0.23%	130.26K	-	-11.91K	-8.38%
Sep 30, 2023	SWISS NATIONAL BANK	0.22%	122.16K	-	1.8K	+1.50%
Sep 30, 2023	BARCLAYS PLC	0.22%	121.01K	-	-37.72K	-23.76%
Sep 30, 2023	CREDIT SUISSE AG/	0.19%	107.66K	-	-13.1K	-10.85%
Sep 30, 2023	ALLIANZ ASSET MANAGEMENT GMBH	0.19%	107.41K	-	-3.76K	-3.38%
Sep 30, 2023	CITIGROUP INC	0.12%	64.99K	-	-538	-0.82%
Sep 30, 2023	RHUMBLINE ADVISERS	0.18%	102.12K	-	1.24K	+1.23%
Sep 30, 2023	STATE OF NEW JERSEY COMMON PENSION FUND D	0.17%	94.77K	-	0	0
Sep 30, 2023	TD ASSET MANAGEMENT INC	0.17%	92.22K	-	43.72K	+90.14%
Sep 30, 2023	ALLIANCEBERNSTEIN L.P.	0.13%	73.58K	-	0	0
Sep 30, 2023	PRUDENTIAL FINANCIAL INC	0.13%	69.65K	-	-43.2K	-38.28%
Sep 30, 2023	SKANDINAVISKA ENSKILDA BANKEN AB (PUBL)	0.11%	62.36K	-	33K	+112.40%
Sep 30, 2023	PDT PARTNERS, LLC	0.08%	46.2K	-	2.79K	+6.43%
Sep 30, 2023	UBS ASSET MANAGEMENT AMERICAS INC	0.09%	47.46K	-	-203.07K	-81.06%
Sep 30, 2023	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.09%	50.22K	-	2.61K	+5.49%
Sep 30, 2023	ROYAL BANK OF CANADA	0.1%	54K	-	4.13K	+8.28%
Sep 30, 2023	JANE STREET GROUP, LLC	0.1%	55.03K	-	-14.6K	-20.96%
Sep 30, 2023	BNP PARIBAS ARBITRAGE, SNC	0.11%	59.24K	-	-6.24K	-9.53%
Sep 30, 2023	CAPTION MANAGEMENT, LLC	0.11%	60K	-	0	0
Sep 30, 2023	UBS GROUP AG	0.11%	60.39K	-	-11.91K	-16.47%
Sep 30, 2023	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0.11%	61.38K	-	-5.74K	-8.55%

Insiders

Among the AGIO insiders holding of 1.68% of the stake in company, CELGENE CORP /DE/, 10 percent owner, holds the largest shares of 1.78M. FOUSE JACQUALYN A, director, is the second largest AGIO insider with ownership of 149.22K shares. GOFF BRIAN, Chief Executive Officer, stands third with possession of 136.58K shares of that stake.

Insiders	Designation	Shares Held
CELGENE CORP /DE/	10 percent owner	1.78M
FOUSE JACQUALYN A	director	149.22K
GOFF BRIAN	Chief Executive Officer	136.58K
SCHENKEIN DAVID P	director	122.85K
GHEUENS SARAH	Chief Medical Officer	64.8K
JONES CECILIA	Chief Financial Officer	37.39K
MARAGANORE JOHN	director	36.21K
MILANOVA TSVETA	Chief Commercial Officer	34.79K
BURNS JAMES WILLIAM	Chief Legal Officer	31.72K
BILLER SCOTT	Chief Scientific Officer	26.51K
SCADDEN DAVID	director	17.6K
BOWDEN CHRISTOPHER	Chief Medical Officer	15.49K
HOERTER STEVEN L.	Chief Commercial Officer	10.94K
BALLAL RAHUL D.	director	7.99K
MILES DARRIN	Chief Commercial Officer	7.21K
FOSTER-CHEEK KAYE I	director	5.52K
WASHBURN THEODORE JAMES JR.	Principal Accounting Officer	868
ALENSON CARMAN	Principal Accounting Officer	0

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Jan 05, 2026	MILANOVA TSVETA	SALE	27.02	2.87K	77.6K	34.79K
Dec 30, 2025	GHEUENS SARAH	SALE	27.09	2.93K	79.43K	64.8K
Dec 30, 2025	GOFF BRIAN	SALE	27.09	12.47K	337.89K	136.58K
Dec 30, 2025	BURNS JAMES WILLIAM	SALE	27.09	2.93K	79.43K	31.72K
Dec 30, 2025	JONES CECILIA	SALE	27.09	2.93K	79.43K	37.39K
Dec 30, 2025	MILANOVA TSVETA	SALE	27.09	2.93K	79.43K	29.19K
Nov 12, 2025	SCADDEN DAVID	SALE	43.84	200	8.77K	17.6K
Nov 11, 2025	GHEUENS SARAH	SALE	43.78	2.45K	107.44K	61.73K
Oct 30, 2025	GHEUENS SARAH	SALE	43.81	200	8.76K	61.73K
Oct 27, 2025	GHEUENS SARAH	SALE	43.92	3.3K	145.02K	61.73K
Oct 08, 2025	SCADDEN DAVID	SALE	41.00	200	8.2K	17.6K
Sep 30, 2025	SCADDEN DAVID	SALE	40.00	200	8K	17.6K
Sep 26, 2025	JONES CECILIA	SALE	36.77	3.65K	134.25K	33.87K
Sep 05, 2025	WASHBURN THEODORE JAMES JR.	SALE	36.87	8.55K	315.09K	868
Aug 27, 2025	SCADDEN DAVID	SALE	40.00	200	8K	17.6K
Aug 08, 2025	GOFF BRIAN	SALE	36.67	11.09K	406.49K	123.53K
Jul 10, 2025	SCADDEN DAVID	SALE	40.00	1.4K	56K	17.6K
Jul 09, 2025	GHEUENS SARAH	SALE	38.76	847	32.83K	61.27K
Jul 01, 2025	GHEUENS SARAH	SALE	34.17	4.09K	139.79K	61.27K
Jun 24, 2025	JONES CECILIA	SALE	33.54	1.78K	59.7K	30.05K
Jun 24, 2025	GOFF BRIAN	SALE	33.54	12.47K	418.28K	105.4K
Jun 24, 2025	MILANOVA TSVETA	SALE	33.54	2.77K	92.91K	26.12K
Jun 24, 2025	GHEUENS SARAH	SALE	33.54	2.91K	97.57K	56.99K
Jun 24, 2025	BURNS JAMES WILLIAM	SALE	33.54	2.8K	93.88K	28.65K
Apr 10, 2025	FOUSE JACQUALYN A	SALE	25.90	7.5K	194.17K	149.22K
Mar 03, 2025	GOFF BRIAN	SALE	35.54	4.15K	147.6K	83.14K
Mar 03, 2025	MILANOVA TSVETA	SALE	35.54	1.68K	59.74K	22.89K
Mar 03, 2025	GHEUENS SARAH	SALE	35.54	1.14K	40.41K	47.1K
Mar 03, 2025	BURNS JAMES WILLIAM	SALE	35.54	1.14K	40.41K	18.65K
Mar 03, 2025	WASHBURN THEODORE JAMES JR.	SALE	35.54	231	8.21K	6.04K
Mar 03, 2025	JONES CECILIA	SALE	35.54	594	21.11K	21.84K
Feb 05, 2025	WASHBURN THEODORE JAMES JR.	SALE	34.39	2.27K	78.13K	5.44K
Jan 06, 2025	MILANOVA TSVETA	SALE	32.18	2.8K	90.23K	18.91K
Nov 08, 2024	WASHBURN THEODORE JAMES JR.	SALE	56.09	772	43.3K	813
Nov 08, 2024	BALLAL RAHUL D.	SALE	59.21	1.5K	88.82K	7.99K
Nov 07, 2024	BALLAL RAHUL D.	SALE	54.41	1.87K	101.64K	7.99K
Nov 07, 2024	BURNS JAMES WILLIAM	SALE	52.56	8.34K	438.4K	15.7K
Sep 26, 2024	JONES CECILIA	SALE	49.03	2.54K	124.63K	20.16K
Aug 08, 2024	GOFF BRIAN	SALE	42.75	11.09K	474.14K	78.79K
Jul 01, 2024	GHEUENS SARAH	SALE	43.85	3.71K	162.46K	43.74K
Jun 05, 2024	GOFF BRIAN	SALE	48.84	12.12K	591.7K	67.19K
Jun 03, 2024	WASHBURN THEODORE JAMES JR.	SALE	44.39	1.36K	60.46K	1.52K
Apr 10, 2024	FOUSE JACQUALYN A	SALE	27.55	7.79K	214.64K	137.4K
Mar 07, 2024	FOSTER-CHEEK KAYE I	SALE	31.62	1.29K	40.63K	5.52K
Mar 06, 2024	FOSTER-CHEEK KAYE I	SALE	31.99	4.42K	141.24K	6.81K
Mar 05, 2024	JONES CECILIA	SALE	32.57	672	21.89K	14.84K
Mar 05, 2024	WASHBURN THEODORE JAMES JR.	SALE	32.57	295	9.61K	3.37K
Mar 05, 2024	BURNS JAMES WILLIAM	SALE	32.57	1.29K	42.11K	34.52K
Mar 05, 2024	FOSTER-CHEEK KAYE I	SALE	32.21	300	9.66K	11.22K
Mar 05, 2024	GOFF BRIAN	SALE	32.57	4.16K	135.36K	53.78K
Mar 05, 2024	GHEUENS SARAH	SALE	32.57	1.29K	42.11K	36.42K
Feb 27, 2024	SCHENKEIN DAVID P	SALE	34.89	57.47K	2.01M	122.85K
Feb 26, 2024	SCHENKEIN DAVID P	SALE	33.19	20.41K	677.44K	122.85K
Feb 23, 2024	SCHENKEIN DAVID P	SALE	33.05	47.73K	1.58M	122.85K
Feb 20, 2024	WASHBURN THEODORE JAMES JR.	SALE	26.63	504	13.42K	2.74K
Feb 14, 2024	BURNS JAMES WILLIAM	SALE	25.14	545	13.7K	31.67K
Feb 14, 2024	GHEUENS SARAH	SALE	25.14	642	16.14K	33.43K
Feb 14, 2024	WASHBURN THEODORE JAMES JR.	SALE	25.14	273	6.86K	3.25K
Jan 24, 2024	GOFF BRIAN	SALE	21.64	7.64K	165.22K	49.44K
Jan 24, 2024	FOUSE JACQUALYN A	SALE	21.64	10.72K	232.02K	129.25K
Jan 24, 2024	BURNS JAMES WILLIAM	SALE	21.64	1.71K	36.96K	30.38K
Jan 24, 2024	GHEUENS SARAH	SALE	21.64	1.71K	36.96K	31.91K
Jan 24, 2024	MILANOVA TSVETA	SALE	21.64	1.62K	35.01K	13.23K
Jan 24, 2024	JONES CECILIA	SALE	21.64	1.89K	40.81K	13.07K
Jan 09, 2024	FOUSE JACQUALYN A	SALE	22.99	8.39K	192.91K	116.08K
Jan 09, 2024	GOFF BRIAN	SALE	22.99	12.07K	277.4K	40.05K
Jan 09, 2024	BURNS JAMES WILLIAM	SALE	22.99	1.16K	26.74K	26.34K
Jan 09, 2024	GHEUENS SARAH	SALE	22.99	1.79K	41.13K	27.87K
Jan 05, 2024	MILANOVA TSVETA	SALE	22.32	2.9K	64.77K	9.4K
Sep 28, 2023	JONES CECILIA	SALE	24.79	2.18K	54.02K	9.58K
Aug 17, 2023	BURNS JAMES WILLIAM	SALE	26.28	6.4K	168.06K	23.89K
Aug 09, 2023	FOSTER-CHEEK KAYE I	SALE	25.96	25K	648.89K	11.52K
Aug 08, 2023	GOFF BRIAN	SALE	25.48	10.18K	259.34K	26.59K
Aug 07, 2023	WASHBURN THEODORE JAMES JR.	SALE	25.39	2.92K	74.1K	2.74K
Aug 01, 2023	WASHBURN THEODORE JAMES JR.	SALE	26.26	1.23K	32.35K	5.66K
Jun 30, 2023	MILANOVA TSVETA	SALE	28.36	1.62K	45.89K	3.83K
Jun 30, 2023	GOFF BRIAN	SALE	28.36	11.45K	324.69K	14.08K
Jun 30, 2023	GHEUENS SARAH	SALE	28.36	1.71K	48.41K	24.16K
Jun 30, 2023	FOUSE JACQUALYN A	SALE	28.36	10.72K	303.96K	106.97K
Jun 30, 2023	BURNS JAMES WILLIAM	SALE	28.36	1.71K	48.41K	30.29K
Jun 30, 2023	JONES CECILIA	SALE	28.36	1.6K	45.29K	3.78K
Apr 03, 2023	SCHENKEIN DAVID P	SALE	22.85	16.36K	373.89K	117.88K
Mar 27, 2023	SCHENKEIN DAVID P	SALE	22.15	20K	443K	117.88K
Mar 13, 2023	SCHENKEIN DAVID P	SALE	22.72	1.67K	37.87K	117.88K
Mar 03, 2023	WASHBURN THEODORE JAMES JR.	SALE	24.29	504	12.24K	2.74K
Feb 27, 2023	SCHENKEIN DAVID P	SALE	25.37	20K	507.4K	117.88K
Feb 16, 2023	WASHBURN THEODORE JAMES JR.	SALE	27.21	233	6.34K	2.67K
Feb 14, 2023	WASHBURN THEODORE JAMES JR.	SALE	28.59	504	14.41K	2.9K
Feb 13, 2023	SCHENKEIN DAVID P	SALE	28.62	20K	572.4K	117.88K
Jan 30, 2023	SCHENKEIN DAVID P	SALE	29.88	3.3K	98.6K	117.88K
Jan 17, 2023	SCHENKEIN DAVID P	SALE	29.49	1.03K	30.49K	117.88K
Feb 25, 2022	WASHBURN THEODORE JAMES JR.	SALE	30.00	108	3.24K	2.55K
Feb 16, 2022	WASHBURN THEODORE JAMES JR.	SALE	30.81	233	7.18K	2.55K
Feb 14, 2022	WASHBURN THEODORE JAMES JR.	SALE	31.25	504	15.75K	2.78K
Jun 21, 2021	ALENSON CARMAN	SALE	61.61	1.78K	109.48K	0
Jun 18, 2021	BOWDEN CHRISTOPHER	SALE	60.11	48.49K	2.91M	15.49K
Jun 17, 2021	BOWDEN CHRISTOPHER	SALE	60.02	2.5K	150.17K	15.49K
Jun 10, 2021	BOWDEN CHRISTOPHER	SALE	60.06	20.85K	1.25M	15.49K
Jun 09, 2021	BOWDEN CHRISTOPHER	SALE	60.16	7.15K	430.12K	15.49K
Jun 08, 2021	BOWDEN CHRISTOPHER	SALE	60.07	6.68K	400.94K	15.49K
Jun 07, 2021	BOWDEN CHRISTOPHER	SALE	60.04	4.27K	256.23K	15.49K
May 14, 2021	MILES DARRIN	SALE	55.41	3.46K	191.83K	7.21K
Apr 20, 2021	BOWDEN CHRISTOPHER	SALE	55.11	14.4K	793.58K	15.49K
Apr 19, 2021	BOWDEN CHRISTOPHER	SALE	55.16	3.21K	177.05K	15.49K
Apr 16, 2021	ALENSON CARMAN	SALE	55.89	1.12K	62.49K	0
Apr 15, 2021	ALENSON CARMAN	SALE	54.00	991	53.51K	1.12K
Mar 05, 2021	MILES DARRIN	SALE	48.58	500	24.29K	10.67K
Mar 01, 2021	MILES DARRIN	SALE	47.99	2.2K	105.58K	11.17K
Sep 02, 2020	ALENSON CARMAN	SALE	39.93	250	9.98K	184
May 20, 2020	BOWDEN CHRISTOPHER	SALE	50.01	3.58K	179.2K	8.31K
Mar 02, 2020	ALENSON CARMAN	SALE	47.30	345	16.32K	184
Feb 26, 2020	ALENSON CARMAN	SALE	47.12	472	22.24K	184
Feb 20, 2020	ALENSON CARMAN	SALE	53.37	2.43K	129.53K	184
Feb 13, 2020	BOWDEN CHRISTOPHER	SALE	50.16	7.1K	356.11K	1.65K
Feb 11, 2020	BOWDEN CHRISTOPHER	SALE	50.02	621	31.06K	1.65K
Feb 04, 2020	BOWDEN CHRISTOPHER	SALE	50.10	35.45K	1.78M	1.65K
Dec 26, 2019	ALENSON CARMAN	SALE	50.09	2.95K	147.77K	184
Nov 13, 2019	FOUSE JACQUALYN A	PURCHASE	31.00	40.32K	1.25M	41.72K
Nov 13, 2019	SCHENKEIN DAVID P	PURCHASE	31.00	8.06K	249.98K	97.57K
Nov 12, 2019	CELGENE CORP /DE/	PURCHASE	31.00	403.23K	12.5M	1.78M
Apr 05, 2019	BILLER SCOTT	SALE	68.12	599	40.8K	26.51K
Apr 01, 2019	BOWDEN CHRISTOPHER	SALE	68.72	100	6.87K	7.24K
Mar 15, 2019	BOWDEN CHRISTOPHER	SALE	64.64	1.3K	84.03K	7.24K
Mar 05, 2019	BILLER SCOTT	SALE	67.73	2.6K	176.1K	26.71K
Mar 04, 2019	HOERTER STEVEN L.	SALE	68.00	5K	340K	10.94K
Mar 01, 2019	HOERTER STEVEN L.	SALE	66.01	5K	330.05K	10.94K
Feb 27, 2019	BILLER SCOTT	SALE	65.00	9K	585K	26.51K
Nov 05, 2018	BILLER SCOTT	SALE	69.44	2.2K	152.77K	51.73K
Oct 05, 2018	BILLER SCOTT	SALE	68.56	900	61.7K	53.03K
Sep 28, 2018	ALENSON CARMAN	SALE	76.45	152	11.62K	0
Sep 12, 2018	MARAGANORE JOHN	SALE	0.00	0	-	36.21K
Sep 11, 2018	MARAGANORE JOHN	SALE	72.52	11.16K	808.96K	38.61K
Sep 05, 2018	ALENSON CARMAN	SALE	83.00	312	25.9K	152
Sep 05, 2018	BILLER SCOTT	SALE	82.52	640	52.81K	59.56K
Aug 30, 2018	BOWDEN CHRISTOPHER	SALE	80.03	1.7K	136.05K	924
Aug 29, 2018	BOWDEN CHRISTOPHER	SALE	80.00	300	24K	924
Aug 24, 2018	HOERTER STEVEN L.	SALE	74.92	2.05K	153.59K	0
Aug 06, 2018	BILLER SCOTT	SALE	78.32	300	23.5K	59.9K
Jul 25, 2018	HOERTER STEVEN L.	SALE	84.58	2.05K	173.39K	0
Jul 10, 2018	BOWDEN CHRISTOPHER	SALE	86.42	1.2K	103.7K	1.72K
Jul 09, 2018	ALENSON CARMAN	SALE	84.94	272	23.1K	0
Jul 05, 2018	BILLER SCOTT	SALE	83.41	2.7K	225.21K	57.5K
Jun 22, 2018	HOERTER STEVEN L.	SALE	97.58	2.05K	200.04K	0
Jun 14, 2018	FOSTER-CHEEK KAYE I	SALE	92.62	2.18K	202K	9.02K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES46.03K15

NET SHARES-46.03K15

SHARES HELD624.8K15

% NET SHARES-107.37%0%

Frequently Asked Questions