How many institutions own ACLX stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own ACLX shares is 287, representing 98.3% of the company's common stock.

Who are the major shareholders selling Arcellx, Inc. stock?

PRICE T ROWE ASSOCIATES INC /MD/, in the last quarter, reduced its stake in ACLX by -12.14% restricting it's holding to 1.26 million shares of worth nearly $103.78M. PERCEPTIVE ADVISORS LLC also lessened -0.39% of the ACLX shares from its portfolio, reducing its holding to 2.47 million shares of worth $202.65M. NEA MANAGEMENT COMPANY, LLC also shunned ACLX shares holding by -18.69% last quarter which brought its holding to 3.05 million shares worth $250.02M.

Investors who are buying ACLX stock?

As per its latest 13F filing, T. ROWE PRICE INVESTMENT MANAGEMENT, INC. increased its stake in ACLX by 226.81% in the last quarter. The institutional holder raised its holding to 6.35 million shares having worth more than $521.53M. LOGOS GLOBAL MANAGEMENT LP also added 100% more shares of ACLX to its portfolio, raising its holding to 165 thousand shares of worth $13.55M. AMERIPRISE FINANCIAL INC also increased its ACLX shares holding by 36.32% which brought its holding to 165.65 thousand shares worth $13.60M.

ACLX's major insiders: who are they?

The insider with the most stakes in ACLX is New Enterprise Associates 15, L.P. , 10 percent owner at the company. Additionally, ACLX stock is highly held by 10 percent owner Novo Holdings A/S and 10 percent owner SR ONE CAPITAL MANAGEMENT, LLC among others.

Did an insider recently sell ACLX stock?

Company executives, directors, and other insiders own 13.45% percent of Arcellx, Inc.'s stock. Within the last six months, there have been 9 transaction(s) in which ACLX insiders have sold stock, totaling 29.29K shares. Insiders that have sold shares include HEERY CHRISTOPHER, GILSON MICHELLE, and PATEL KAVITA.

Which insider recently purchased ACLX stock?

There have been 0 transaction(s) during the past 6-months in which Arcellx, Inc. insiders have bought stock, totalling 0 shares

How much of ACLX does insiders own?

Around 150.04K Arcellx, Inc. shares are held by insiders, which represents about 13.45% of ACLX stock.

Who is the insider with the largest stake?

ACLX 10 percent owner, New Enterprise Associates 15, L.P. holds the largest portfolio of the company's shares. ACLX shares owned by New total nearly 6.75 million.

Which institution holds the most shares in ACLX?

PRICE T ROWE ASSOCIATES INC /MD/ is the largest institutional owner in ACLX which holds 1.26 million shares worth $103.78M or 2.25% of the total ACLX shares outstanding followed by CAPITAL WORLD INVESTORS with ownership of 783.01 thousand shares representing 1.39% of the ACLX ownership. PERCEPTIVE ADVISORS LLC is the third largest stakeholder with 2.47 million shares or 4.39% of the ownership worth more than $202.65M.

Is Arcellx, Inc. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the ACLX is concerned, it is a stock which is optionable.

Is there a short position on ACLX's shares?

Number of ACLX shares short is 6.45M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding ACLX shares are there?

As of today, 57.82M shares of ACLX are outstanding.

Is there many float in ACLX stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, ACLX has 39.70M shares in float.

ACLX short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for ACLX is 7.65.

Arcellx (ACLX) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares11.15

Short Percent Of Float15.22

Shares Outstanding57.82M

Shares Float39.70M

Shares Short6.45M

Short Ratio7.65

15.22%

Short % of Float

11.15%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

13.45% Percentage of Shares held by All Insiders

98.3% Percentage of Shares held by All Institutions

113.57% Percentage of Float held by Institutions

287

Number of Institutions Holding Shares

Institutional Ownership

About 98.3% of ACLX shares are held by financial institutions. PRICE T ROWE ASSOCIATES INC /MD/ is the top corporate investor, holding 1.26M shares valued at $103.78M. A 2.25% stake in Arcellx, Inc. is owned by the company. CAPITAL WORLD INVESTORS owns 783.01K shares valued at $64.29M, which translates its holding of 1.39% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Sep 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	2.25%	1.26M	103.78M	-174.72K	-12.14%
Sep 30, 2025	CAPITAL WORLD INVESTORS	1.39%	783.01K	64.29M	0	0
Sep 30, 2025	PERCEPTIVE ADVISORS LLC	4.39%	2.47M	202.65M	-9.65K	-0.39%
Sep 30, 2025	NEA MANAGEMENT COMPANY, LLC	5.42%	3.05M	250.02M	-700K	-18.69%
Sep 30, 2025	BLACKROCK, INC.	6.03%	3.39M	278.15M	-80.29K	-2.32%
Sep 30, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	11.3%	6.35M	521.53M	4.41M	+226.81%
Sep 30, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	0.18%	100K	8.21M	-23.03K	-18.72%
Sep 30, 2025	LOGOS GLOBAL MANAGEMENT LP	0.29%	165K	13.55M	165K	+100.00%
Sep 30, 2025	AMERIPRISE FINANCIAL INC	0.29%	165.65K	13.6M	44.13K	+36.32%
Sep 30, 2025	BAKER BROS. ADVISORS LP	0.3%	166.83K	13.7M	0	0
Sep 30, 2025	VICTORY CAPITAL MANAGEMENT INC	0.31%	172.05K	14.13M	-27.69K	-13.86%
Sep 30, 2025	UBS GROUP AG	0.34%	189.38K	15.55M	40.46K	+27.17%
Sep 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.41%	232.2K	19.06M	-9.21K	-3.82%
Sep 30, 2025	TD ASSET MANAGEMENT INC	0.41%	232.71K	19.11M	129.25K	+124.93%
Sep 30, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.44%	247.41K	20.31M	-28.27K	-10.25%
Sep 30, 2025	AMERICAN CENTURY COMPANIES INC	0.73%	411.93K	33.82M	-19.54K	-4.53%
Sep 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.75%	420.81K	34.55M	37.67K	+9.83%
Sep 30, 2025	LORD, ABBETT & CO. LLC	0.75%	424K	34.81M	86.42K	+25.60%
Sep 30, 2025	JPMORGAN CHASE & CO	1.57%	882.5K	72.45M	-94.47K	-9.67%
Sep 30, 2025	AJU IB INVESTMENT CO., LTD.	1.86%	1.05M	86M	0	0
Sep 30, 2025	VESTAL POINT CAPITAL, LP	2.22%	1.25M	102.63M	-1.5M	-54.55%
Sep 30, 2025	SR ONE CAPITAL MANAGEMENT, LP	4.17%	2.35M	192.66M	0	0
Sep 30, 2025	VANGUARD GROUP INC	6.95%	3.91M	320.77M	-37.8K	-0.96%
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.23%	131.52K	10.8M	-545	-0.41%
Sep 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0.26%	143.53K	11.78M	15.47K	+12.08%
Sep 30, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.3%	168.63K	13.84M	-98.48K	-36.87%
Sep 30, 2025	FIRST TURN MANAGEMENT, LLC	0.56%	313.73K	25.76M	98.51K	+45.77%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.59%	330.49K	27.13M	11.21K	+3.51%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.65%	926.3K	76.06M	-35.47K	-3.69%
Sep 30, 2025	JANUS HENDERSON GROUP PLC	1.8%	1.01M	83.25M	-9.66K	-0.94%
Sep 30, 2025	RA CAPITAL MANAGEMENT, L.P.	5.4%	3.04M	249.3M	0	0
Sep 30, 2025	FMR LLC	10.25%	5.76M	473M	-210.83K	-3.53%
Sep 30, 2025	GILEAD SCIENCES, INC.	11.95%	6.72M	551.78M	0	0
Sep 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.04%	20.35K	1.67M	2.53K	+14.20%
Sep 30, 2025	ERSTE ASSET MANAGEMENT GMBH	0.04%	21K	1.66M	0	0
Sep 30, 2025	STRS OHIO	0.04%	21.57K	1.77M	7.27K	+50.83%
Sep 30, 2025	HARBOR CAPITAL ADVISORS, INC.	0.04%	21.67K	1.78M	-3.05K	-12.33%
Sep 30, 2025	ALPS ADVISORS INC	0.04%	25.19K	2.07M	-4.47K	-15.08%
Sep 30, 2025	CONGRESS ASSET MANAGEMENT CO /MA	0.05%	25.3K	2.08M	93	+0.37%
Sep 30, 2025	KNOTT DAVID M JR	0.05%	25.7K	2.11M	0	0
Sep 30, 2025	HEALTHINVEST PARTNERS AB	0.05%	25.73K	224.28K	0	0
Sep 30, 2025	BLUE OWL CAPITAL HOLDINGS LP	0.05%	26.82K	2.2M	26.82K	+100.00%
Sep 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.89%	500K	41.05M	5K	+1.01%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.3%	171.24K	14.06M	-91.12K	-34.73%
Sep 30, 2025	LEGAL & GENERAL GROUP PLC	0.05%	28.99K	2.38M	-5.82K	-16.72%
Sep 30, 2025	DEKABANK DEUTSCHE GIROZENTRALE	0.05%	30K	2.27M	0	0
Sep 30, 2025	SECTOR GAMMA AS	0.06%	32.01K	2.63M	7.01K	+28.04%
Sep 30, 2025	INVESCO LTD.	0.06%	33.67K	2.76M	1.99K	+6.27%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0.06%	34.43K	2.83M	3.84K	+12.54%
Sep 30, 2025	TEMA ETFS LLC	0.07%	36.81K	3.02M	2.94K	+8.68%
Sep 30, 2025	NEOS INVESTMENT MANAGEMENT LLC	0.07%	36.81K	3.02M	2.94K	+8.68%
Sep 30, 2025	SCHRODER INVESTMENT MANAGEMENT GROUP	0.08%	42.48K	3.36M	-17.52K	-29.20%
Sep 30, 2025	EDMOND DE ROTHSCHILD HOLDING S.A.	0.08%	45.48K	3.73M	0	0
Sep 30, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.09%	49.24K	4.04M	-7.13K	-12.65%
Sep 30, 2025	PATHWAY CAPITAL MANAGEMENT, LP	0.09%	51.05K	4.19M	51.05K	+100.00%
Sep 30, 2025	RHUMBLINE ADVISERS	0.09%	52.43K	4.3M	-2.71K	-4.92%
Sep 30, 2025	SWISS NATIONAL BANK	0.1%	53.4K	4.38M	-9.5K	-15.10%
Sep 30, 2025	PIER CAPITAL, LLC	0.11%	60.22K	4.94M	-3.42K	-5.37%
Sep 30, 2025	RHENMAN & PARTNERS ASSET MANAGEMENT AB	0.12%	65.25K	5.36M	-2K	-2.97%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.12%	68.83K	5.65M	-6.6K	-8.74%
Sep 30, 2025	MONACO ASSET MANAGEMENT SAM	0.14%	78.59K	6.45M	78.59K	+100.00%
Sep 30, 2025	NUVEEN, LLC	0.15%	83.43K	6.85M	-3.99K	-4.57%
Sep 30, 2025	DEUTSCHE BANK AG\	0.71%	399.32K	32.78M	69.96K	+21.24%
Sep 30, 2025	STATE STREET CORP	2.71%	1.53M	125.29M	-66.29K	-4.16%
Sep 30, 2025	PARADIGM BIOCAPITAL ADVISORS LP	8.27%	4.65M	381.68M	0	0
Sep 30, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	0.32%	178.98K	14.69M	-7.33K	-3.94%
Sep 30, 2025	DIMENSIONAL FUND ADVISORS LP	0.15%	83.52K	6.86M	-259.6K	-75.66%
Sep 30, 2025	CITIGROUP INC	0.17%	92.85K	7.62M	-13.43K	-12.63%
Sep 30, 2025	HIGHVISTA STRATEGIES LLC	0.17%	96.18K	7.9M	60.46K	+169.30%
Sep 30, 2025	PARKMAN HEALTHCARE PARTNERS LLC	0.27%	149.85K	12.3M	-24.43K	-14.02%
Sep 30, 2025	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.27%	150K	12.32M	150K	+100.00%
Sep 30, 2025	NORTHERN TRUST CORP	0.6%	334.55K	27.47M	-11.42K	-3.30%
Sep 30, 2025	MORGAN STANLEY	0.77%	432.88K	35.54M	-84.63K	-16.35%
Sep 30, 2025	WOODLINE PARTNERS LP	0.43%	241.39K	19.82M	0	0
Sep 30, 2025	GOLDMAN SACHS GROUP INC	0.8%	448.44K	36.82M	-62.16K	-12.17%
Sep 30, 2025	SCHONFELD STRATEGIC ADVISORS LLC	0.89%	500.32K	41.08M	153.59K	+44.30%
Sep 30, 2025	CITADEL ADVISORS LLC	1.82%	1.02M	83.86M	823.09K	+414.94%
Sep 30, 2025	BARCLAYS PLC	0.19%	107.66K	8.84M	-31.72K	-22.76%
Sep 30, 2025	RAYMOND JAMES FINANCIAL INC	0.23%	126.5K	10.39M	-7.54K	-5.63%
Sep 30, 2025	BAMCO INC /NY/	0.98%	550.24K	45.17M	32.23K	+6.22%
Sep 30, 2025	CORMORANT ASSET MANAGEMENT, LP	1.38%	775K	63.63M	-25K	-3.13%
Jun 30, 2025	TD ASSET MANAGEMENT INC	0.18%	103.46K	6.81M	-64.86K	-38.53%
Jun 30, 2025	MARSHALL WACE, LLP	0.2%	111.81K	7.36M	96.41K	+626.03%
Jun 30, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	0.22%	123.03K	8.1M	-30K	-19.60%
Jun 30, 2025	RAYMOND JAMES FINANCIAL INC	0.24%	134.05K	8.83M	5.27K	+4.09%
Jun 30, 2025	BAKER BROS. ADVISORS LP	0.3%	166.83K	10.99M	166.83K	+100.00%
Jun 30, 2025	PARKMAN HEALTHCARE PARTNERS LLC	0.31%	174.28K	11.48M	106.89K	+158.61%
Jun 30, 2025	SUSQUEHANNA PORTFOLIO STRATEGIES, LLC	0.09%	50.94K	3.35M	50.94K	+100.00%
Jun 30, 2025	CAPTION MANAGEMENT, LLC	0.24%	133.6K	8.8M	-142K	-51.52%
Jun 30, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.49%	275.68K	18.15M	-1.43K	-0.51%
Jun 30, 2025	NORTHERN TRUST CORP	0.62%	345.98K	22.78M	-57.87K	-14.33%
Jun 30, 2025	BALYASNY ASSET MANAGEMENT L.P.	0.1%	54.79K	3.61M	54.79K	+100.00%
Jun 30, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.1%	56.37K	3.71M	-2.14K	-3.65%
Jun 30, 2025	SCHRODER INVESTMENT MANAGEMENT GROUP	0.11%	60K	3.95M	60K	+100.00%
Jun 30, 2025	GILEAD SCIENCES, INC.	11.95%	6.72M	442.56M	0	0
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.57%	319.27K	21.02M	-17.68K	-5.25%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.58%	326.8K	21.52M	322.1K	+6,853.19%
Jun 30, 2025	DEKABANK DEUTSCHE GIROZENTRALE	0.05%	30K	2.29M	0	0
Jun 30, 2025	NEOS INVESTMENT MANAGEMENT LLC	0.06%	33.87K	2.23M	5.42K	+19.05%
Jun 30, 2025	PIER CAPITAL, LLC	0.11%	63.63K	4.19M	-4.34K	-6.39%
Jun 30, 2025	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.12%	66.42K	4.37M	-11.81K	-15.10%
Jun 30, 2025	RHENMAN & PARTNERS ASSET MANAGEMENT AB	0.12%	67.25K	4.43M	23.75K	+54.60%
Jun 30, 2025	RA CAPITAL MANAGEMENT, L.P.	5.4%	3.04M	199.96M	0	0
Jun 30, 2025	BLACKROCK, INC.	6.17%	3.47M	228.38M	-499.39K	-12.59%
Jun 30, 2025	HIGHVISTA STRATEGIES LLC	0.06%	35.71K	2.35M	-11.78K	-24.81%
Jun 30, 2025	BAMCO INC /NY/	0.92%	518.01K	34.11M	50.75K	+10.86%
Jun 30, 2025	BANK OF NEW YORK MELLON CORP	0.23%	132.07K	8.7M	-11.55K	-8.04%
Jun 30, 2025	NICHOLAS INVESTMENT PARTNERS, LP	0.07%	41.07K	2.7M	41.07K	+100.00%
Jun 30, 2025	GREAT POINT PARTNERS LLC	0.18%	100K	6.59M	55K	+122.22%
Jun 30, 2025	STEMPOINT CAPITAL LP	0.36%	201.45K	13.27M	-72.32K	-26.42%
Jun 30, 2025	FIRST TURN MANAGEMENT, LLC	0.38%	215.22K	14.17M	215.22K	+100.00%
Jun 30, 2025	WOODLINE PARTNERS LP	0.43%	241.39K	15.9M	76.08K	+46.03%
Jun 30, 2025	MORGAN STANLEY	0.92%	517.51K	34.08M	55.18K	+11.94%
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	2.56%	1.44M	94.75M	-400.85K	-21.79%
Jun 30, 2025	ALPS ADVISORS INC	0.05%	29.66K	1.95M	29.66K	+100.00%
Jun 30, 2025	NEA MANAGEMENT COMPANY, LLC	6.66%	3.75M	246.63M	0	0
Jun 30, 2025	PARADIGM BIOCAPITAL ADVISORS LP	8.27%	4.65M	306.14M	156.98K	+3.49%
Jun 30, 2025	ALLIANCEBERNSTEIN L.P.	0.09%	48.16K	3.17B	-3.14K	-6.12%
Jun 30, 2025	SAMSARA BIOCAPITAL, LLC	0.18%	101.46K	6.68M	-33.82K	-25.00%
Jun 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.13%	75.43K	4.97B	31.08K	+70.06%
Jun 30, 2025	UBS GROUP AG	0.26%	148.92K	9.81M	-60.66K	-28.94%
Jun 30, 2025	VESTAL POINT CAPITAL, LP	4.89%	2.75M	181.09M	362.28K	+15.17%
Jun 30, 2025	VANGUARD GROUP INC	7.02%	3.94M	259.77M	-40.27K	-1.01%
Jun 30, 2025	AMERICAN CENTURY COMPANIES INC	0.77%	431.47K	28.41M	377.15K	+694.29%
Jun 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.88%	495K	32.6M	-35K	-6.60%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.91%	510.61K	33.62M	335.82K	+192.13%
Jun 30, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	3.46%	1.94M	128M	278.59K	+16.73%
Jun 30, 2025	AJU IB INVESTMENT CO., LTD.	1.86%	1.05M	68.98M	0	0
Jun 30, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	0.33%	186.31K	12.27M	186.31K	+100.00%
Jun 30, 2025	CITADEL ADVISORS LLC	0.35%	198.36K	13.06M	-527.76K	-72.68%
Jun 30, 2025	DEUTSCHE BANK AG\	0.59%	329.36K	21.69M	-14.33K	-4.17%
Jun 30, 2025	LORD, ABBETT & CO. LLC	0.6%	337.58K	22.23M	-326.95K	-49.20%
Jun 30, 2025	DIMENSIONAL FUND ADVISORS LP	0.61%	343.13K	22.59M	-143.14K	-29.44%
Jun 30, 2025	SCHONFELD STRATEGIC ADVISORS LLC	0.62%	346.73K	22.83M	113.21K	+48.48%
Jun 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.68%	383.14K	25.23M	377.65K	+6,882.61%
Jun 30, 2025	DECHENG CAPITAL LLC	0.97%	547.61K	4.46M	497.61K	+995.22%
Jun 30, 2025	CAPITAL WORLD INVESTORS	1.39%	783.01K	51.56M	73.64K	+10.38%
Jun 30, 2025	CORMORANT ASSET MANAGEMENT, LP	1.42%	800K	52.68M	-250K	-23.81%
Jun 30, 2025	BARCLAYS PLC	0.25%	139.38K	9.18M	61.74K	+79.52%
Jun 30, 2025	VICTORY CAPITAL MANAGEMENT INC	0.36%	199.74K	13.15M	21.63K	+12.14%
Jun 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.43%	241.41K	15.9M	222.97K	+1,209.23%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0.47%	262.36K	17.28M	98.69K	+60.30%
Jun 30, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.48%	267.11K	17.59M	2.36K	+0.89%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.71%	961.78K	63.34M	-58.76K	-5.76%
Jun 30, 2025	JPMORGAN CHASE & CO	1.74%	976.97K	64.33M	293.39K	+42.92%
Jun 30, 2025	JANUS HENDERSON GROUP PLC	1.82%	1.02M	67.39M	-486.91K	-32.24%
Jun 30, 2025	STATE STREET CORP	2.83%	1.59M	104.85M	-74.14K	-4.45%
Jun 30, 2025	SR ONE CAPITAL MANAGEMENT, LP	4.17%	2.35M	154.53M	0	0
Jun 30, 2025	PERCEPTIVE ADVISORS LLC	4.41%	2.48M	163.18M	-448.48K	-15.32%
Jun 30, 2025	FMR LLC	10.62%	5.97M	393.27M	-331.53K	-5.26%
Jun 30, 2025		0.16%	87.42K	5.76M	-24.37K	-21.80%
Jun 30, 2025	TREXQUANT INVESTMENT LP	0.08%	43.18K	2.84M	43.18K	+100.00%
Jun 30, 2025	EDMOND DE ROTHSCHILD HOLDING S.A.	0.08%	45.48K	2.99M	0	0
Mar 31, 2025	TD ASSET MANAGEMENT INC	0.3%	168.32K	11.04M	4.4K	+2.69%
Mar 31, 2025	STEMPOINT CAPITAL LP	0.5%	273.77K	17.96M	273.77K	+100.00%
Mar 31, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0.28%	152.02K	9.97M	-117.36K	-43.57%
Mar 31, 2025	BANK OF NEW YORK MELLON CORP	0.26%	143.62K	9.42M	-792	-0.55%
Mar 31, 2025	SAMSARA BIOCAPITAL, LLC	0.24%	135.28K	8.87M	-118.37K	-46.67%
Mar 31, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	3.01%	1.67M	109.23M	959.22K	+135.88%
Mar 31, 2025	IKARIAN CAPITAL, LLC	0.2%	111.6K	7.32M	111.6K	+100.00%
Mar 31, 2025		0.2%	111.79K	7.33M	111.79K	+100.00%
Mar 31, 2025	CAPTION MANAGEMENT, LLC	0.22%	121.2K	7.95M	-147.4K	-54.88%
Mar 31, 2025	DIMENSIONAL FUND ADVISORS LP	0.88%	486.27K	31.9M	181.18K	+59.39%
Mar 31, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	0.28%	153.03K	10.04M	32K	+26.44%
Mar 31, 2025	SCHONFELD STRATEGIC ADVISORS LLC	0.42%	233.52K	15.32M	200.79K	+613.33%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.32%	174.79K	11.47M	-115.22K	-39.73%
Mar 31, 2025	WOODLINE PARTNERS LP	0.3%	165.31K	10.84M	39.66K	+31.56%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0.3%	163.67K	10.74M	15.56K	+10.51%
Mar 31, 2025	FMR LLC	11.41%	6.3M	413.52M	-1.65M	-20.77%
Mar 31, 2025	PARADIGM BIOCAPITAL ADVISORS LP	8.13%	4.49M	294.68M	120.43K	+2.75%
Mar 31, 2025	CITADEL ADVISORS LLC	1.31%	726.13K	47.63M	700.9K	+2,778.49%
Mar 31, 2025	CAPITAL WORLD INVESTORS	1.28%	709.37K	46.53M	456.5K	+180.52%
Mar 31, 2025	JANUS HENDERSON GROUP PLC	2.73%	1.51M	102.64M	-46.6K	-2.99%
Mar 31, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.31%	173.06K	11.35M	18.66K	+12.08%
Mar 31, 2025	CORMORANT ASSET MANAGEMENT, LP	1.9%	1.05M	68.88M	-250K	-19.23%
Mar 31, 2025	AJU IB INVESTMENT CO., LTD.	1.9%	1.05M	68.72M	0	0
Mar 31, 2025	VANGUARD GROUP INC	7.21%	3.99M	261.43M	655.06K	+19.67%
Mar 31, 2025	BLACKROCK, INC.	7.18%	3.97M	260.27M	113.55K	+2.95%
Mar 31, 2025	NEA MANAGEMENT COMPANY, LLC	6.78%	3.75M	245.69M	0	0
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.85%	1.02M	66.96M	41.51K	+4.24%
Mar 31, 2025	JPMORGAN CHASE & CO	1.24%	683.58K	44.84M	459.13K	+204.55%
Mar 31, 2025	LORD, ABBETT & CO. LLC	1.2%	664.53K	43.59M	-310.31K	-31.83%
Mar 31, 2025	AFFINITY ASSET ADVISORS, LLC	0.96%	530K	34.77M	105K	+24.71%
Mar 31, 2025	BAMCO INC /NY/	0.85%	467.26K	30.65M	118.93K	+34.14%
Mar 31, 2025	MORGAN STANLEY	0.84%	462.33K	30.33M	-155.78K	-25.20%
Mar 31, 2025	NORTHERN TRUST CORP	0.73%	403.84K	26.49M	-6.89K	-1.68%
Mar 31, 2025	DEUTSCHE BANK AG\	0.62%	343.69K	22.55M	-835	-0.24%
Mar 31, 2025	RA CAPITAL MANAGEMENT, L.P.	5.5%	3.04M	199.2M	249.2K	+8.94%
Mar 31, 2025	PERCEPTIVE ADVISORS LLC	5.3%	2.93M	191.98M	-552.41K	-15.88%
Mar 31, 2025	SR ONE CAPITAL MANAGEMENT, LP	4.25%	2.35M	153.94M	0	0
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.61%	336.95K	22.1M	-6.14K	-1.79%
Mar 31, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.5%	277.1K	18.18M	140.9K	+103.45%
Mar 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	3.33%	1.84M	120.68M	-281.7K	-13.28%
Mar 31, 2025	STATE STREET CORP	3.02%	1.67M	109.32M	-108.92K	-6.14%
Mar 31, 2025	GILEAD SCIENCES, INC.	12.16%	6.72M	440.88M	0	0
Mar 31, 2025	VESTAL POINT CAPITAL, LP	4.32%	2.39M	156.63M	1.91M	+402.68%
Mar 31, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.48%	264.76K	17.37M	-2.63K	-0.98%
Mar 31, 2025	ARTIA GLOBAL PARTNERS LP	0.41%	229.09K	15.03M	-700	-0.30%
Mar 31, 2025	UBS GROUP AG	0.38%	209.57K	13.75M	2.03K	+0.98%
Mar 31, 2025	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.36%	200K	13.12M	200K	+100.00%
Mar 31, 2025	VICTORY CAPITAL MANAGEMENT INC	0.32%	178.11K	11.68M	-6.07K	-3.30%
Mar 31, 2025	RAYMOND JAMES FINANCIAL INC	0.23%	128.78K	8.45M	-1.82K	-1.40%
Mar 31, 2024	FEDERATED HERMES, INC.	0.44%	231.66K	16.11M	17.06K	+7.95%
Mar 31, 2024	SQUAREPOINT OPS LLC	0.23%	121.01K	8.42M	-8.15K	-6.31%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.23%	121.06K	8.42M	-10.87K	-8.24%
Mar 31, 2024	RAFFERTY ASSET MANAGEMENT, LLC	0.24%	126.75K	8.82M	14.8K	+13.22%
Mar 31, 2024	STEMPOINT CAPITAL LP	0.27%	140.27K	9.76M	-173.34K	-55.27%
Mar 31, 2024	SOLEUS CAPITAL MANAGEMENT, L.P.	0.29%	150K	10.43M	-9K	-5.66%
Mar 31, 2024	TWO SIGMA INVESTMENTS, LP	0.36%	188.85K	13.13M	43.58K	+30.00%
Mar 31, 2024	RUSSELL INVESTMENTS GROUP, LTD.	0.37%	195.44K	13.59M	5.9K	+3.11%
Mar 31, 2024	CANDRIAM S.C.A.	0.42%	220.01K	15.3M	-62.01K	-21.99%
Mar 31, 2024	EAGLE ASSET MANAGEMENT INC	0.43%	224.53K	15.04M	224.53K	+100.00%
Mar 31, 2024	VICTORY CAPITAL MANAGEMENT INC	0.45%	235.87K	16.4M	80.21K	+51.53%
Mar 31, 2024	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.49%	255K	17.74M	95K	+59.38%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.22%	114.8K	7.98M	106.2K	+1,234.88%
Mar 31, 2024	CUTTER CAPITAL MANAGEMENT, LP	0.2%	107K	7.44M	107K	+100.00%
Mar 31, 2024	WOODLINE PARTNERS LP	0.2%	104.06K	7.24M	0	0
Mar 31, 2024	UBS GROUP AG	0.2%	103.48K	7.2M	6.44K	+6.63%
Mar 31, 2024	JANUS HENDERSON GROUP PLC	2.91%	1.52M	105.86M	-15.9K	-1.03%
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	2.57%	1.34M	93.51M	84.37K	+6.70%
Mar 31, 2024	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	1.88%	982.86K	68.36M	60.46K	+6.56%
Mar 31, 2024	MORGAN STANLEY	1.33%	696.76K	48.46M	23.48K	+3.49%
Mar 31, 2024	FMR LLC	10.32%	5.39M	375.19M	1.02M	+23.19%
Mar 31, 2024	BLACKROCK INC.	5.86%	3.07M	213.25M	47.53K	+1.57%
Mar 31, 2024	SR ONE CAPITAL MANAGEMENT, LP	4.49%	2.35M	163.21M	-800K	-25.42%
Mar 31, 2024	VANGUARD GROUP INC	4.26%	2.23M	155.02M	167.04K	+8.10%
Mar 31, 2024	LORD, ABBETT & CO. LLC	2.29%	1.2M	83.33M	1.55K	+0.13%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.79%	414.54K	28.83M	220.25K	+113.37%
Mar 31, 2024	NORTHERN TRUST CORP	0.69%	359.46K	25M	-3.96K	-1.09%
Mar 31, 2024	GREAT POINT PARTNERS LLC	0.57%	300K	20.87M	251.74K	+521.58%
Mar 31, 2024	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.52%	272.01K	18.92M	-60.9K	-18.29%
Mar 31, 2024	BAMCO INC /NY/	0.48%	248.99K	17.32M	185.49K	+292.12%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.36%	186.78K	12.99M	-92.84K	-33.20%
Mar 31, 2024	PARKMAN HEALTHCARE PARTNERS LLC	0.3%	156.6K	10.89M	-11.66K	-6.93%
Mar 31, 2024	CITIGROUP INC	0.22%	114.95K	7.99M	62.62K	+119.65%
Mar 31, 2024	UBS ASSET MANAGEMENT AMERICAS INC	0.51%	265.41K	18.46M	135.27K	+103.95%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.52%	272.79K	18.97M	-82.9K	-23.31%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.54%	282.01K	19.61M	17.83K	+6.75%
Mar 31, 2024	AFFINITY ASSET ADVISORS, LLC	0.57%	300K	20.87M	-40K	-11.76%
Mar 31, 2024	PFM HEALTH SCIENCES, LP	0.58%	303.21K	21.09M	-31.99K	-9.54%
Mar 31, 2024	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.69%	363.09K	25.25M	127.33K	+54.01%
Mar 31, 2024	VOYA INVESTMENT MANAGEMENT LLC	0.73%	380.32K	26.45M	298.85K	+366.81%
Mar 31, 2024	DEUTSCHE BANK AG\	0.86%	447.78K	31.14M	308.6K	+221.71%
Mar 31, 2024	SAMSARA BIOCAPITAL, LLC	0.87%	453.64K	31.55M	-6.8K	-1.48%
Mar 31, 2024	JPMORGAN CHASE & CO	1.06%	551.75K	38.37M	-50.16K	-8.33%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	1.6%	838.47K	58.32M	53.07K	+6.76%
Mar 31, 2024	SUVRETTA CAPITAL MANAGEMENT, LLC	2.99%	1.56M	108.66M	-873.62K	-35.86%
Mar 31, 2024	CORMORANT ASSET MANAGEMENT, LP	3.4%	1.78M	123.8M	80K	+4.71%
Mar 31, 2024	STATE STREET CORP	3.61%	1.89M	131.11M	111.28K	+6.27%
Mar 31, 2024	NEA MANAGEMENT COMPANY, LLC	7.16%	3.75M	260.48M	0	0
Mar 31, 2024	PARADIGM BIOCAPITAL ADVISORS LP	7.3%	3.82M	265.55M	159.47K	+4.36%
Mar 31, 2024	MOODY ALDRICH PARTNERS LLC	0.04%	20.56K	1.43M	20.56K	+100.00%
Mar 31, 2024	FORA CAPITAL, LLC	0.04%	22.22K	1.55M	0	0
Mar 31, 2024	MARTINGALE ASSET MANAGEMENT L P	0.04%	22.93K	1.59M	-4.2K	-15.49%
Mar 31, 2024	CONGRESS ASSET MANAGEMENT CO /MA	0.04%	23.23K	1.62M	-1.83K	-7.31%
Mar 31, 2024	STATE OF WISCONSIN INVESTMENT BOARD	0.05%	26.63K	1.85M	-4.76K	-15.15%
Mar 31, 2024	ALGERT GLOBAL LLC	0.05%	28.31K	1.97M	19.12K	+208.05%
Mar 31, 2024	LEGAL & GENERAL GROUP PLC	0.06%	29.34K	2.04B	-418	-1.40%
Mar 31, 2024	DEKABANK DEUTSCHE GIROZENTRALE	0.06%	30K	2.11M	0	0
Mar 31, 2024	MYDA ADVISORS LLC	0.07%	35K	2.43M	-5K	-12.50%
Mar 31, 2024	PRINCIPAL FINANCIAL GROUP INC	0.07%	36.84K	2.56M	26.2K	+246.26%
Mar 31, 2024	ALPS ADVISORS INC	0.07%	37.24K	2.59M	4.83K	+14.92%
Mar 31, 2024	CREDIT SUISSE AG/	0.07%	38.74K	2.69M	1.56K	+4.18%
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	0.08%	39.58K	2.75M	2.58K	+6.97%
Mar 31, 2024	FIRST TRUST ADVISORS LP	0.08%	40.28K	2.8M	14.77K	+57.92%
Mar 31, 2024	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.09%	45.7K	3.18M	8.72K	+23.57%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.09%	47.2K	3.28M	1.75K	+3.84%
Mar 31, 2024	RHUMBLINE ADVISERS	0.1%	53K	3.69M	1.57K	+3.05%
Mar 31, 2024	FRANKLIN RESOURCES INC	0.1%	54.34K	3.78M	36.1K	+197.86%
Mar 31, 2024	SWISS NATIONAL BANK	0.11%	56.4K	3.92M	-800	-1.40%
Mar 31, 2024	EAM INVESTORS, LLC	0.13%	66.05K	4.59M	1K	+1.54%
Mar 31, 2024	THRIVENT FINANCIAL FOR LUTHERANS	0.13%	67.54K	4.7M	67.54K	+100.00%
Mar 31, 2024	TD ASSET MANAGEMENT INC	0.17%	89.92K	6.25B	8.6K	+10.58%
Mar 31, 2024	VESTAL POINT CAPITAL, LP	0.19%	100K	6.96M	40K	+66.67%
Mar 31, 2024	QUBE RESEARCH & TECHNOLOGIES LTD	0.19%	101.19K	7.04M	87.26K	+626.65%
Mar 31, 2024	PERCEPTIVE ADVISORS LLC	7.52%	3.93M	273.58M	-611.25K	-13.45%
Dec 31, 2023	FMR LLC	9.04%	4.38M	243.04M	-158.18K	-3.49%
Dec 31, 2023	VOYA INVESTMENT MANAGEMENT LLC	0.17%	81.47K	4.52M	24.32K	+42.55%
Dec 31, 2023	JANE STREET GROUP, LLC	0.17%	84.39K	4.68M	74.49K	+752.00%
Dec 31, 2023	UBS GROUP AG	0.2%	97.05K	5.39M	47.61K	+96.32%
Dec 31, 2023	WOODLINE PARTNERS LP	0.21%	104.06K	5.78M	104.06K	+100.00%
Dec 31, 2023	RAFFERTY ASSET MANAGEMENT, LLC	0.23%	111.95K	6.21M	-46.83K	-29.49%
Dec 31, 2023	PERCEPTIVE ADVISORS LLC	9.38%	4.54M	252.24M	578.83K	+14.59%
Dec 31, 2023	WALLEYE CAPITAL LLC	0.24%	118.34K	6.57M	-97.94K	-45.28%
Dec 31, 2023	CAAS CAPITAL MANAGEMENT LP	0.26%	124.96K	6.94M	0	0
Dec 31, 2023	CUBIST SYSTEMATIC STRATEGIES, LLC	0.26%	127.06K	7.05M	127.06K	+100.00%
Dec 31, 2023	SQUAREPOINT OPS LLC	0.27%	129.16K	7.17M	129.16K	+100.00%
Dec 31, 2023	BARCLAYS PLC	0.27%	129.43K	7.18M	43.24K	+50.17%
Dec 31, 2023	UBS ASSET MANAGEMENT AMERICAS INC	0.27%	130.14K	7.22M	-55.46K	-29.88%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.27%	131.93K	7.32M	14.67K	+12.51%
Dec 31, 2023	DEUTSCHE BANK AG\	0.29%	139.19K	7.72M	120.1K	+629.11%
Dec 31, 2023	TWO SIGMA INVESTMENTS, LP	0.3%	145.27K	8.06M	3.18K	+2.24%
Dec 31, 2023	VICTORY CAPITAL MANAGEMENT INC	0.32%	155.65K	8.64M	126K	+424.96%
Dec 31, 2023	SOLEUS CAPITAL MANAGEMENT, L.P.	0.33%	159K	8.82M	-484.78K	-75.30%
Dec 31, 2023	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.33%	160K	8.88M	160K	+100.00%
Dec 31, 2023	PARKMAN HEALTHCARE PARTNERS LLC	0.35%	168.26K	9.34M	-35.22K	-17.31%
Dec 31, 2023	RUSSELL INVESTMENTS GROUP, LTD.	0.39%	189.54K	10.52M	11.2K	+6.28%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.4%	194.29K	10.78M	84.84K	+77.52%
Dec 31, 2023	FEDERATED HERMES, INC.	0.44%	214.6K	11.91M	143.21K	+200.61%
Dec 31, 2023	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.49%	235.76K	13.08M	132.71K	+128.78%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.55%	264.18K	14.66M	3.72K	+1.43%
Dec 31, 2023	NUVEEN ASSET MANAGEMENT, LLC	0.58%	279.63K	15.52M	35.43K	+14.51%
Dec 31, 2023	CANDRIAM S.C.A.	0.58%	282.01K	15.65M	-116.01K	-29.15%
Dec 31, 2023		0.65%	313.6K	17.41M	313.6K	+100.00%
Dec 31, 2023	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.69%	332.9K	18.48M	-60K	-15.27%
Dec 31, 2023	PFM HEALTH SCIENCES, LP	0.69%	335.2K	18.6M	94.86K	+39.47%
Dec 31, 2023	AFFINITY ASSET ADVISORS, LLC	0.7%	340K	18.87M	-60K	-15.00%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.73%	355.69K	19.74M	-519.17K	-59.34%
Dec 31, 2023	NORTHERN TRUST CORP	0.75%	363.42K	20.17M	-4.03K	-1.10%
Dec 31, 2023	SAMSARA BIOCAPITAL, LLC	0.95%	460.44K	25.55M	-153.48K	-25.00%
Dec 31, 2023	JPMORGAN CHASE & CO	1.24%	601.91K	33.41M	38.01K	+6.74%
Dec 31, 2023	MORGAN STANLEY	1.39%	673.29K	37.37M	568.03K	+539.65%
Dec 31, 2023	DEEP TRACK CAPITAL, LP	1.5%	725.15K	40.25M	725.15K	+100.00%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.62%	785.4K	43.59M	46.35K	+6.27%
Dec 31, 2023	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	1.9%	922.4K	51.19M	12.22K	+1.34%
Dec 31, 2023	LORD, ABBETT & CO. LLC	2.47%	1.2M	66.41M	98.53K	+8.97%
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	2.6%	1.26M	69.94M	323.31K	+34.51%
Dec 31, 2023	JANUS HENDERSON GROUP PLC	3.18%	1.54M	85.39M	-237.23K	-13.36%
Dec 31, 2023	CORMORANT ASSET MANAGEMENT, LP	3.51%	1.7M	94.35M	-450K	-20.93%
Dec 31, 2023	STATE STREET CORP	3.66%	1.77M	98.45M	-240.41K	-11.94%
Dec 31, 2023	VANGUARD GROUP INC	4.26%	2.06M	114.43M	23.26K	+1.14%
Dec 31, 2023	SUVRETTA CAPITAL MANAGEMENT, LLC	5.03%	2.44M	135.2M	-433.99K	-15.12%
Dec 31, 2023	BLACKROCK INC.	6.23%	3.02M	167.53M	310.88K	+11.48%
Dec 31, 2023	SR ONE CAPITAL MANAGEMENT, LP	6.5%	3.15M	174.64M	-800K	-20.27%
Dec 31, 2023	PARADIGM BIOCAPITAL ADVISORS LP	7.55%	3.66M	203.05M	705.5K	+23.89%
Dec 31, 2023	NEA MANAGEMENT COMPANY, LLC	7.73%	3.75M	207.86M	0	0
Sep 30, 2023	MORGAN STANLEY	0.22%	105.26K	-	-173.85K	-62.29%
Sep 30, 2023	TWO SIGMA INVESTMENTS, LP	0.3%	142.1K	-	-184K	-56.42%
Sep 30, 2023	RAFFERTY ASSET MANAGEMENT, LLC	0.33%	158.78K	-	14.68K	+10.19%
Sep 30, 2023	RUSSELL INVESTMENTS GROUP, LTD.	0.37%	178.34K	-	62K	+53.29%
Sep 30, 2023	UBS ASSET MANAGEMENT AMERICAS INC	0.39%	185.59K	-	168.99K	+1,018.03%
Sep 30, 2023	WALLEYE CAPITAL LLC	0.45%	216.27K	-	-1.36K	-0.63%
Sep 30, 2023	NUVEEN ASSET MANAGEMENT, LLC	0.51%	244.19K	-	7.13K	+3.01%
Sep 30, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.54%	260.46K	-	19.52K	+8.10%
Sep 30, 2023	NORTHERN TRUST CORP	0.76%	367.45K	-	7.9K	+2.20%
Sep 30, 2023		0.81%	388.12K	-	388.12K	+100.00%
Sep 30, 2023	CANDRIAM S.C.A.	0.83%	398.02K	-	0	0
Sep 30, 2023	VIVO CAPITAL, LLC	1.05%	503.57K	-	69.78K	+16.09%
Sep 30, 2023	SOLEUS CAPITAL MANAGEMENT, L.P.	1.34%	643.78K	-	-358.22K	-35.75%
Sep 30, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.54%	739.05K	-	53.83K	+7.86%
Sep 30, 2023	GOLDMAN SACHS GROUP INC	1.82%	874.86K	-	-144.06K	-14.14%
Sep 30, 2023	NOVO HOLDINGS A/S	2.23%	1.08M	-	75K	+7.50%
Sep 30, 2023	LORD, ABBETT & CO. LLC	2.28%	1.1M	-	-167.34K	-13.22%
Sep 30, 2023	CORMORANT ASSET MANAGEMENT, LP	4.47%	2.15M	-	150K	+7.50%
Sep 30, 2023	BLACKROCK INC.	5.63%	2.71M	-	105.18K	+4.04%
Sep 30, 2023	PARADIGM BIOCAPITAL ADVISORS LP	6.14%	2.95M	-	606.12K	+25.83%
Sep 30, 2023	NEA MANAGEMENT COMPANY, LLC	7.79%	3.75M	-	0	0
Sep 30, 2023	SR ONE CAPITAL MANAGEMENT, LP	8.2%	3.95M	-	0	0
Sep 30, 2023	PERCEPTIVE ADVISORS LLC	8.24%	3.97M	-	-50.42K	-1.26%
Sep 30, 2023	STRS OHIO	0.06%	29.48K	-	23.28K	+375.50%
Sep 30, 2023	VICTORY CAPITAL MANAGEMENT INC	0.06%	29.65K	-	-12.06K	-28.91%
Sep 30, 2023	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.07%	33.18K	-	-9.69K	-22.59%
Sep 30, 2023	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0.07%	33.82K	-	-52.19K	-60.68%
Sep 30, 2023	CREDIT SUISSE AG/	0.07%	34.48K	-	-474	-1.36%
Sep 30, 2023	ALPS ADVISORS INC	0.07%	35.71K	-	432	+1.22%
Sep 30, 2023	ALLIANCEBERNSTEIN L.P.	0.08%	36.21K	-	0	0
Sep 30, 2023	WELLS FARGO & COMPANY/MN	0.08%	36.66K	-	-3.87K	-9.54%
Sep 30, 2023	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.08%	37.95K	-	37.95K	+100.00%
Sep 30, 2023	PUTNAM INVESTMENTS LLC	0.09%	41.26K	-	-356	-0.86%
Sep 30, 2023	TWO SIGMA ADVISERS, LP	0.09%	41.7K	-	-88.1K	-67.87%
Sep 30, 2023	UBS GROUP AG	0.1%	49.43K	-	-72.08K	-59.32%
Sep 30, 2023	BAMCO INC /NY/	0.1%	50K	-	10K	+25.00%
Sep 30, 2023	FMR LLC	9.43%	4.54M	-	-153.65K	-3.28%
Sep 30, 2023	RHUMBLINE ADVISERS	0.11%	51.35K	-	923	+1.83%
Sep 30, 2023	SCHONFELD STRATEGIC ADVISORS LLC	0.12%	56.36K	-	7.1K	+14.41%
Sep 30, 2023	VOYA INVESTMENT MANAGEMENT LLC	0.12%	57.15K	-	169	+0.30%
Sep 30, 2023	SWISS NATIONAL BANK	0.13%	63.3K	-	11.2K	+21.50%
Sep 30, 2023	HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND	0.13%	64K	-	64K	+100.00%
Sep 30, 2023	CITIGROUP INC	0.14%	69.02K	-	5.62K	+8.86%
Sep 30, 2023	FEDERATED HERMES, INC.	0.15%	71.39K	-	-93.28K	-56.65%
Sep 30, 2023	HIGHVISTA STRATEGIES LLC	0.16%	78.03K	-	15.16K	+24.11%
Sep 30, 2023	TD ASSET MANAGEMENT INC	0.17%	81.6K	-	52.8K	+183.33%
Sep 30, 2023	BARCLAYS PLC	0.18%	86.19K	-	10.59K	+14.01%
Sep 30, 2023	CLOUGH CAPITAL PARTNERS L P	0.21%	102.76K	-	-3.1K	-2.93%
Sep 30, 2023	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.21%	103.05K	-	-171.52K	-62.47%
Sep 30, 2023	BANK OF NEW YORK MELLON CORP	0.24%	117.27K	-	-13.26K	-10.16%

Insiders

Among the ACLX insiders holding of 13.45% of the stake in company, NEW ENTERPRISE ASSOCIATES 15, L.P., 10 percent owner, holds the largest shares of 6.75M. NOVO HOLDINGS A/S, 10 percent owner, is the second largest ACLX insider with ownership of 4.02M shares. SR ONE CAPITAL MANAGEMENT, LLC, 10 percent owner, stands third with possession of 1.66M shares of that stake.

Insiders	Designation	Shares Held
NEW ENTERPRISE ASSOCIATES 15, L.P.	10 percent owner	6.75M
NOVO HOLDINGS A/S	10 percent owner	4.02M
SR ONE CAPITAL MANAGEMENT, LLC	10 percent owner	1.66M
CARROLL JILL	director	1.48M
ELGHANDOUR RAMI	SEE REMARKS	149.19K
GILSON MICHELLE	CHIEF FINANCIAL OFFICER	8.47K
HEERY CHRISTOPHER	CHIEF MEDICAL OFFICER	284
WARE OLIVIA C	director	0
PATEL KAVITA	director	0
SANDELL SCOTT D	director	0
MAKHZOUMI MOHAMAD	director	0
FLORENCE ANTHONY A. JR.	director	0
BASKETT FOREST	director	0

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Nov 17, 2025	HEERY CHRISTOPHER	SALE	90.00	340	30.6K	284
Oct 15, 2025	GILSON MICHELLE	SALE	91.04	5.36K	488.32K	8.47K
Oct 06, 2025	GILSON MICHELLE	SALE	86.22	1.06K	91.73K	13.83K
Oct 03, 2025	GILSON MICHELLE	SALE	86.00	4.88K	419.87K	14.89K
Sep 30, 2025	HEERY CHRISTOPHER	SALE	82.20	1.53K	125.76K	624
Sep 29, 2025	HEERY CHRISTOPHER	SALE	80.16	73	5.85K	21.66K
Sep 26, 2025	HEERY CHRISTOPHER	SALE	80.12	12.4K	993.16K	21.73K
Sep 19, 2025	HEERY CHRISTOPHER	SALE	80.00	300	24K	34.13K
Sep 18, 2025	HEERY CHRISTOPHER	SALE	80.01	3.34K	267.47K	34.43K
Jun 10, 2025	PATEL KAVITA	SALE	67.36	1.5K	101.04K	0
May 27, 2025	GILSON MICHELLE	SALE	64.38	8.45K	543.91K	19.78K
May 20, 2025	PATEL KAVITA	SALE	58.43	1.5K	87.65K	0
Apr 29, 2025	PATEL KAVITA	SALE	64.20	1.5K	96.3K	0
Apr 08, 2025	PATEL KAVITA	SALE	57.50	1.5K	86.25K	0
Mar 18, 2025	PATEL KAVITA	SALE	71.64	1.5K	107.46K	0
Feb 26, 2025	ELGHANDOUR RAMI	SALE	62.69	10.89K	682.62K	149.19K
Feb 25, 2025	PATEL KAVITA	SALE	63.16	1.5K	94.74K	0
Feb 24, 2025	HEERY CHRISTOPHER	SALE	64.88	208	13.49K	37.49K
Feb 04, 2025	PATEL KAVITA	SALE	64.57	1.5K	96.86K	0
Jan 14, 2025	PATEL KAVITA	SALE	67.32	300	20.2K	0
Jan 08, 2025	GILSON MICHELLE	SALE	73.69	4K	294.55K	9.58K
Jan 08, 2025	ELGHANDOUR RAMI	SALE	73.69	13.84K	1.02M	117.28K
Jan 08, 2025	HEERY CHRISTOPHER	SALE	73.69	3.55K	261.83K	25.09K
Jan 07, 2025	GILSON MICHELLE	SALE	75.53	4.76K	359.51K	13.58K
Jan 07, 2025	ELGHANDOUR RAMI	SALE	75.53	16.47K	1.24M	131.11K
Jan 07, 2025	HEERY CHRISTOPHER	SALE	75.53	4.23K	319.48K	28.64K
Jan 06, 2025	GILSON MICHELLE	SALE	77.17	5.62K	433.75K	27.59K
Jan 06, 2025	HEERY CHRISTOPHER	SALE	77.17	2.98K	229.57K	32.87K
Jan 06, 2025	ELGHANDOUR RAMI	SALE	77.17	15.11K	1.17M	147.59K
Jan 03, 2025	HEERY CHRISTOPHER	SALE	79.55	2.98K	236.66K	35.84K
Jan 03, 2025	GILSON MICHELLE	SALE	79.55	5.62K	447.22K	33.21K
Jan 03, 2025	ELGHANDOUR RAMI	SALE	79.55	15.11K	1.2M	162.7K
Dec 24, 2024	PATEL KAVITA	SALE	77.61	100	7.76K	0
Dec 03, 2024	PATEL KAVITA	SALE	96.05	300	28.81K	0
Nov 15, 2024	GILSON MICHELLE	SALE	95.00	100	9.5K	0
Nov 12, 2024	PATEL KAVITA	SALE	106.33	1.5K	159.5K	0
Nov 11, 2024	PATEL KAVITA	SALE	106.91	3.01K	321.26K	0
Nov 08, 2024	GILSON MICHELLE	SALE	102.33	801	81.97K	1.76K
Nov 08, 2024	PATEL KAVITA	SALE	105.46	25.79K	2.72M	0
Nov 07, 2024	PATEL KAVITA	SALE	99.30	8.48K	841.86K	0
Oct 22, 2024	PATEL KAVITA	SALE	89.69	1.5K	134.54K	0
Oct 01, 2024	PATEL KAVITA	SALE	82.24	1.5K	123.36K	0
Sep 17, 2024	GILSON MICHELLE	SALE	77.88	8.73K	679.59K	6.92K
Sep 10, 2024	PATEL KAVITA	SALE	74.41	1.5K	111.62K	0
Sep 05, 2024	HEERY CHRISTOPHER	SALE	70.02	3.42K	239.53K	9.28K
Sep 03, 2024	HEERY CHRISTOPHER	SALE	70.07	2.9K	203.2K	9.28K
Aug 26, 2024	HEERY CHRISTOPHER	SALE	71.34	15.25K	1.09M	9.28K
Aug 20, 2024	PATEL KAVITA	SALE	65.88	1.5K	98.82K	0
Aug 16, 2024	HEERY CHRISTOPHER	SALE	65.05	5.45K	354.53K	9.28K
Aug 01, 2024	HEERY CHRISTOPHER	SALE	61.13	732	44.75K	9.28K
Jul 30, 2024	PATEL KAVITA	SALE	62.95	200	12.59K	0
Jul 16, 2024	HEERY CHRISTOPHER	SALE	65.30	10.9K	711.85K	9.28K
Jul 12, 2024	HEERY CHRISTOPHER	SALE	60.21	1.78K	107.18K	9.28K
Jul 11, 2024	HEERY CHRISTOPHER	SALE	60.01	3.67K	220.3K	9.28K
Jul 09, 2024	PATEL KAVITA	SALE	57.15	648	37.04K	0
Jul 01, 2024	HEERY CHRISTOPHER	SALE	56.20	2.78K	156.39K	9.28K
Jun 27, 2024	PATEL KAVITA	SALE	54.51	5.03K	274.11K	0
Jun 26, 2024	GILSON MICHELLE	SALE	54.25	551	29.89K	6.92K
Jun 12, 2024	HEERY CHRISTOPHER	SALE	56.03	82	4.59K	9.28K
May 24, 2024	GILSON MICHELLE	SALE	50.71	12.12K	614.66K	19.79K
May 01, 2024	HEERY CHRISTOPHER	SALE	53.55	100	5.36K	8.94K
Apr 16, 2024	WARE OLIVIA C	SALE	56.03	2.61K	146.35K	0
Apr 01, 2024	ELGHANDOUR RAMI	SALE	68.42	2.71K	185.48K	69.25K
Mar 26, 2024	HEERY CHRISTOPHER	SALE	70.19	861	60.43K	8.94K
Mar 22, 2024	HEERY CHRISTOPHER	SALE	72.25	1K	72.25K	8.94K
Mar 21, 2024	CARROLL JILL	SALE	70.55	504.26K	35.58M	1.48M
Mar 18, 2024	GILSON MICHELLE	SALE	69.73	3.04K	212.19K	9.49K
Mar 15, 2024	WARE OLIVIA C	SALE	70.99	3.34K	236.88K	0
Feb 12, 2024	ELGHANDOUR RAMI	SALE	64.46	11.17K	719.95K	92.34K
Feb 12, 2024	HEERY CHRISTOPHER	SALE	64.46	2.97K	191.25K	30.3K
Feb 09, 2024	ELGHANDOUR RAMI	SALE	63.40	13.89K	880.34K	103.51K
Feb 09, 2024	HEERY CHRISTOPHER	SALE	63.40	3.69K	233.81K	33.27K
Feb 08, 2024	ELGHANDOUR RAMI	SALE	62.29	13.01K	810.45K	117.39K
Feb 08, 2024	HEERY CHRISTOPHER	SALE	62.29	3.46K	215.29K	36.96K
Jan 04, 2024	ELGHANDOUR RAMI	SALE	55.27	29.07K	1.61M	60.19K
Jan 04, 2024	GILSON MICHELLE	SALE	55.27	8.51K	470.55K	16.31K
Jan 04, 2024	HEERY CHRISTOPHER	SALE	55.27	7.6K	419.93K	17.86K
Dec 18, 2023	HEERY CHRISTOPHER	SALE	51.86	845	43.82K	7.8K
Dec 14, 2023	CARROLL JILL	SALE	49.13	504.26K	24.77M	1.98M
Aug 04, 2023	HEERY CHRISTOPHER	SALE	35.38	3K	106.13K	7.8K
Jul 03, 2023	HEERY CHRISTOPHER	SALE	31.75	3K	95.25K	7.8K
Jun 01, 2023	CARROLL JILL	SALE	44.35	25.56K	1.13M	2.49M
May 31, 2023	ELGHANDOUR RAMI	SALE	44.27	2.6K	115.1K	36.17K
May 31, 2023	CARROLL JILL	SALE	41.50	315.16K	13.08M	2.51M
May 25, 2023	GILSON MICHELLE	SALE	42.77	6K	256.62K	9.49K
May 24, 2023	GILSON MICHELLE	SALE	41.64	150	6.25K	15.49K
May 11, 2023	SR ONE CAPITAL MANAGEMENT, LLC	SALE	46.15	3.8K	175.55K	1.66M
May 11, 2023	CARROLL JILL	SALE	46.15	6.49K	299.28K	2.83M
May 10, 2023	HEERY CHRISTOPHER	SALE	45.18	2.2K	99.27K	7.8K
May 09, 2023	HEERY CHRISTOPHER	SALE	45.00	500	22.5K	9.99K
May 05, 2023	HEERY CHRISTOPHER	SALE	45.00	1.2K	54K	10.49K
May 03, 2023	HEERY CHRISTOPHER	SALE	43.56	2.6K	113.24K	11.69K
Apr 24, 2023	HEERY CHRISTOPHER	SALE	40.00	20K	800.07K	11.69K
Apr 19, 2023	HEERY CHRISTOPHER	SALE	35.01	15.64K	547.66K	11.69K
Apr 18, 2023	HEERY CHRISTOPHER	SALE	35.00	6K	210K	14.99K
Apr 03, 2023	HEERY CHRISTOPHER	SALE	31.17	402	12.53K	15.59K
Feb 09, 2023	HEERY CHRISTOPHER	SALE	30.77	6.97K	214.33K	15.59K
Feb 09, 2023	ELGHANDOUR RAMI	SALE	30.77	31.44K	967.42K	38.77K
Feb 03, 2023	HEERY CHRISTOPHER	SALE	35.11	1.26K	44.07K	0
Jan 03, 2023	HEERY CHRISTOPHER	SALE	31.11	2.5K	77.78K	0
Dec 23, 2022	SANDELL SCOTT D	SALE	31.67	195	6.18K	0
Dec 22, 2022	BASKETT FOREST	SALE	31.45	1.63K	51.21K	0
Dec 21, 2022	MAKHZOUMI MOHAMAD	SALE	30.74	179	5.5K	0
Dec 21, 2022	FLORENCE ANTHONY A. JR.	SALE	30.74	179	5.5K	0
Dec 21, 2022	SANDELL SCOTT D	SALE	30.74	179	5.5K	0
Dec 13, 2022	HEERY CHRISTOPHER	SALE	30.03	12.5K	375.32K	0
Jun 21, 2022	NEW ENTERPRISE ASSOCIATES 15, L.P.	PURCHASE	16.00	312.5K	5M	6.75M
Jun 21, 2022	BASKETT FOREST	PURCHASE	16.00	312.5K	5M	6.75M
Feb 08, 2022	CARROLL JILL	PURCHASE	15.00	1.6M	24M	2.03M
Feb 08, 2022	SR ONE CAPITAL MANAGEMENT, LLC	PURCHASE	15.00	1.6M	24M	2.03M
Feb 08, 2022	NEW ENTERPRISE ASSOCIATES 15, L.P.	PURCHASE	15.00	1.58M	23.75M	6.43M
Feb 08, 2022	NOVO HOLDINGS A/S	PURCHASE	15.00	833.33K	12.5M	4.02M

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES29.29K9

NET SHARES-29.29K9

SHARES HELD150.04K9

% NET SHARES-119.52%0%

Frequently Asked Questions

Stock Outstanding Shares

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares11.15

Short Percent Of Float15.22

Shares Outstanding57.82M

Shares Float39.70M

Shares Short6.45M

Short Ratio7.65

15.22%

Short % of Float

11.15%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

13.45% Percentage of Shares held by All Insiders

98.3% Percentage of Shares held by All Institutions

113.57% Percentage of Float held by Institutions

287

Number of Institutions Holding Shares

Institutional Ownership

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Sep 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	2.25%	1.26M	103.78M	-174.72K	-12.14%
Sep 30, 2025	CAPITAL WORLD INVESTORS	1.39%	783.01K	64.29M	0	0
Sep 30, 2025	PERCEPTIVE ADVISORS LLC	4.39%	2.47M	202.65M	-9.65K	-0.39%
Sep 30, 2025	NEA MANAGEMENT COMPANY, LLC	5.42%	3.05M	250.02M	-700K	-18.69%
Sep 30, 2025	BLACKROCK, INC.	6.03%	3.39M	278.15M	-80.29K	-2.32%
Sep 30, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	11.3%	6.35M	521.53M	4.41M	+226.81%
Sep 30, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	0.18%	100K	8.21M	-23.03K	-18.72%
Sep 30, 2025	LOGOS GLOBAL MANAGEMENT LP	0.29%	165K	13.55M	165K	+100.00%
Sep 30, 2025	AMERIPRISE FINANCIAL INC	0.29%	165.65K	13.6M	44.13K	+36.32%
Sep 30, 2025	BAKER BROS. ADVISORS LP	0.3%	166.83K	13.7M	0	0
Sep 30, 2025	VICTORY CAPITAL MANAGEMENT INC	0.31%	172.05K	14.13M	-27.69K	-13.86%
Sep 30, 2025	UBS GROUP AG	0.34%	189.38K	15.55M	40.46K	+27.17%
Sep 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.41%	232.2K	19.06M	-9.21K	-3.82%
Sep 30, 2025	TD ASSET MANAGEMENT INC	0.41%	232.71K	19.11M	129.25K	+124.93%
Sep 30, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.44%	247.41K	20.31M	-28.27K	-10.25%
Sep 30, 2025	AMERICAN CENTURY COMPANIES INC	0.73%	411.93K	33.82M	-19.54K	-4.53%
Sep 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.75%	420.81K	34.55M	37.67K	+9.83%
Sep 30, 2025	LORD, ABBETT & CO. LLC	0.75%	424K	34.81M	86.42K	+25.60%
Sep 30, 2025	JPMORGAN CHASE & CO	1.57%	882.5K	72.45M	-94.47K	-9.67%
Sep 30, 2025	AJU IB INVESTMENT CO., LTD.	1.86%	1.05M	86M	0	0
Sep 30, 2025	VESTAL POINT CAPITAL, LP	2.22%	1.25M	102.63M	-1.5M	-54.55%
Sep 30, 2025	SR ONE CAPITAL MANAGEMENT, LP	4.17%	2.35M	192.66M	0	0
Sep 30, 2025	VANGUARD GROUP INC	6.95%	3.91M	320.77M	-37.8K	-0.96%
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.23%	131.52K	10.8M	-545	-0.41%
Sep 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0.26%	143.53K	11.78M	15.47K	+12.08%
Sep 30, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.3%	168.63K	13.84M	-98.48K	-36.87%
Sep 30, 2025	FIRST TURN MANAGEMENT, LLC	0.56%	313.73K	25.76M	98.51K	+45.77%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.59%	330.49K	27.13M	11.21K	+3.51%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.65%	926.3K	76.06M	-35.47K	-3.69%
Sep 30, 2025	JANUS HENDERSON GROUP PLC	1.8%	1.01M	83.25M	-9.66K	-0.94%
Sep 30, 2025	RA CAPITAL MANAGEMENT, L.P.	5.4%	3.04M	249.3M	0	0
Sep 30, 2025	FMR LLC	10.25%	5.76M	473M	-210.83K	-3.53%
Sep 30, 2025	GILEAD SCIENCES, INC.	11.95%	6.72M	551.78M	0	0
Sep 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.04%	20.35K	1.67M	2.53K	+14.20%
Sep 30, 2025	ERSTE ASSET MANAGEMENT GMBH	0.04%	21K	1.66M	0	0
Sep 30, 2025	STRS OHIO	0.04%	21.57K	1.77M	7.27K	+50.83%
Sep 30, 2025	HARBOR CAPITAL ADVISORS, INC.	0.04%	21.67K	1.78M	-3.05K	-12.33%
Sep 30, 2025	ALPS ADVISORS INC	0.04%	25.19K	2.07M	-4.47K	-15.08%
Sep 30, 2025	CONGRESS ASSET MANAGEMENT CO /MA	0.05%	25.3K	2.08M	93	+0.37%
Sep 30, 2025	KNOTT DAVID M JR	0.05%	25.7K	2.11M	0	0
Sep 30, 2025	HEALTHINVEST PARTNERS AB	0.05%	25.73K	224.28K	0	0
Sep 30, 2025	BLUE OWL CAPITAL HOLDINGS LP	0.05%	26.82K	2.2M	26.82K	+100.00%
Sep 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.89%	500K	41.05M	5K	+1.01%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.3%	171.24K	14.06M	-91.12K	-34.73%
Sep 30, 2025	LEGAL & GENERAL GROUP PLC	0.05%	28.99K	2.38M	-5.82K	-16.72%
Sep 30, 2025	DEKABANK DEUTSCHE GIROZENTRALE	0.05%	30K	2.27M	0	0
Sep 30, 2025	SECTOR GAMMA AS	0.06%	32.01K	2.63M	7.01K	+28.04%
Sep 30, 2025	INVESCO LTD.	0.06%	33.67K	2.76M	1.99K	+6.27%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0.06%	34.43K	2.83M	3.84K	+12.54%
Sep 30, 2025	TEMA ETFS LLC	0.07%	36.81K	3.02M	2.94K	+8.68%
Sep 30, 2025	NEOS INVESTMENT MANAGEMENT LLC	0.07%	36.81K	3.02M	2.94K	+8.68%
Sep 30, 2025	SCHRODER INVESTMENT MANAGEMENT GROUP	0.08%	42.48K	3.36M	-17.52K	-29.20%
Sep 30, 2025	EDMOND DE ROTHSCHILD HOLDING S.A.	0.08%	45.48K	3.73M	0	0
Sep 30, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.09%	49.24K	4.04M	-7.13K	-12.65%
Sep 30, 2025	PATHWAY CAPITAL MANAGEMENT, LP	0.09%	51.05K	4.19M	51.05K	+100.00%
Sep 30, 2025	RHUMBLINE ADVISERS	0.09%	52.43K	4.3M	-2.71K	-4.92%
Sep 30, 2025	SWISS NATIONAL BANK	0.1%	53.4K	4.38M	-9.5K	-15.10%
Sep 30, 2025	PIER CAPITAL, LLC	0.11%	60.22K	4.94M	-3.42K	-5.37%
Sep 30, 2025	RHENMAN & PARTNERS ASSET MANAGEMENT AB	0.12%	65.25K	5.36M	-2K	-2.97%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.12%	68.83K	5.65M	-6.6K	-8.74%
Sep 30, 2025	MONACO ASSET MANAGEMENT SAM	0.14%	78.59K	6.45M	78.59K	+100.00%
Sep 30, 2025	NUVEEN, LLC	0.15%	83.43K	6.85M	-3.99K	-4.57%
Sep 30, 2025	DEUTSCHE BANK AG\	0.71%	399.32K	32.78M	69.96K	+21.24%
Sep 30, 2025	STATE STREET CORP	2.71%	1.53M	125.29M	-66.29K	-4.16%
Sep 30, 2025	PARADIGM BIOCAPITAL ADVISORS LP	8.27%	4.65M	381.68M	0	0
Sep 30, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	0.32%	178.98K	14.69M	-7.33K	-3.94%
Sep 30, 2025	DIMENSIONAL FUND ADVISORS LP	0.15%	83.52K	6.86M	-259.6K	-75.66%
Sep 30, 2025	CITIGROUP INC	0.17%	92.85K	7.62M	-13.43K	-12.63%
Sep 30, 2025	HIGHVISTA STRATEGIES LLC	0.17%	96.18K	7.9M	60.46K	+169.30%
Sep 30, 2025	PARKMAN HEALTHCARE PARTNERS LLC	0.27%	149.85K	12.3M	-24.43K	-14.02%
Sep 30, 2025	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.27%	150K	12.32M	150K	+100.00%
Sep 30, 2025	NORTHERN TRUST CORP	0.6%	334.55K	27.47M	-11.42K	-3.30%
Sep 30, 2025	MORGAN STANLEY	0.77%	432.88K	35.54M	-84.63K	-16.35%
Sep 30, 2025	WOODLINE PARTNERS LP	0.43%	241.39K	19.82M	0	0
Sep 30, 2025	GOLDMAN SACHS GROUP INC	0.8%	448.44K	36.82M	-62.16K	-12.17%
Sep 30, 2025	SCHONFELD STRATEGIC ADVISORS LLC	0.89%	500.32K	41.08M	153.59K	+44.30%
Sep 30, 2025	CITADEL ADVISORS LLC	1.82%	1.02M	83.86M	823.09K	+414.94%
Sep 30, 2025	BARCLAYS PLC	0.19%	107.66K	8.84M	-31.72K	-22.76%
Sep 30, 2025	RAYMOND JAMES FINANCIAL INC	0.23%	126.5K	10.39M	-7.54K	-5.63%
Sep 30, 2025	BAMCO INC /NY/	0.98%	550.24K	45.17M	32.23K	+6.22%
Sep 30, 2025	CORMORANT ASSET MANAGEMENT, LP	1.38%	775K	63.63M	-25K	-3.13%
Jun 30, 2025	TD ASSET MANAGEMENT INC	0.18%	103.46K	6.81M	-64.86K	-38.53%
Jun 30, 2025	MARSHALL WACE, LLP	0.2%	111.81K	7.36M	96.41K	+626.03%
Jun 30, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	0.22%	123.03K	8.1M	-30K	-19.60%
Jun 30, 2025	RAYMOND JAMES FINANCIAL INC	0.24%	134.05K	8.83M	5.27K	+4.09%
Jun 30, 2025	BAKER BROS. ADVISORS LP	0.3%	166.83K	10.99M	166.83K	+100.00%
Jun 30, 2025	PARKMAN HEALTHCARE PARTNERS LLC	0.31%	174.28K	11.48M	106.89K	+158.61%
Jun 30, 2025	SUSQUEHANNA PORTFOLIO STRATEGIES, LLC	0.09%	50.94K	3.35M	50.94K	+100.00%
Jun 30, 2025	CAPTION MANAGEMENT, LLC	0.24%	133.6K	8.8M	-142K	-51.52%
Jun 30, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.49%	275.68K	18.15M	-1.43K	-0.51%
Jun 30, 2025	NORTHERN TRUST CORP	0.62%	345.98K	22.78M	-57.87K	-14.33%
Jun 30, 2025	BALYASNY ASSET MANAGEMENT L.P.	0.1%	54.79K	3.61M	54.79K	+100.00%
Jun 30, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.1%	56.37K	3.71M	-2.14K	-3.65%
Jun 30, 2025	SCHRODER INVESTMENT MANAGEMENT GROUP	0.11%	60K	3.95M	60K	+100.00%
Jun 30, 2025	GILEAD SCIENCES, INC.	11.95%	6.72M	442.56M	0	0
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.57%	319.27K	21.02M	-17.68K	-5.25%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.58%	326.8K	21.52M	322.1K	+6,853.19%
Jun 30, 2025	DEKABANK DEUTSCHE GIROZENTRALE	0.05%	30K	2.29M	0	0
Jun 30, 2025	NEOS INVESTMENT MANAGEMENT LLC	0.06%	33.87K	2.23M	5.42K	+19.05%
Jun 30, 2025	PIER CAPITAL, LLC	0.11%	63.63K	4.19M	-4.34K	-6.39%
Jun 30, 2025	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.12%	66.42K	4.37M	-11.81K	-15.10%
Jun 30, 2025	RHENMAN & PARTNERS ASSET MANAGEMENT AB	0.12%	67.25K	4.43M	23.75K	+54.60%
Jun 30, 2025	RA CAPITAL MANAGEMENT, L.P.	5.4%	3.04M	199.96M	0	0
Jun 30, 2025	BLACKROCK, INC.	6.17%	3.47M	228.38M	-499.39K	-12.59%
Jun 30, 2025	HIGHVISTA STRATEGIES LLC	0.06%	35.71K	2.35M	-11.78K	-24.81%
Jun 30, 2025	BAMCO INC /NY/	0.92%	518.01K	34.11M	50.75K	+10.86%
Jun 30, 2025	BANK OF NEW YORK MELLON CORP	0.23%	132.07K	8.7M	-11.55K	-8.04%
Jun 30, 2025	NICHOLAS INVESTMENT PARTNERS, LP	0.07%	41.07K	2.7M	41.07K	+100.00%
Jun 30, 2025	GREAT POINT PARTNERS LLC	0.18%	100K	6.59M	55K	+122.22%
Jun 30, 2025	STEMPOINT CAPITAL LP	0.36%	201.45K	13.27M	-72.32K	-26.42%
Jun 30, 2025	FIRST TURN MANAGEMENT, LLC	0.38%	215.22K	14.17M	215.22K	+100.00%
Jun 30, 2025	WOODLINE PARTNERS LP	0.43%	241.39K	15.9M	76.08K	+46.03%
Jun 30, 2025	MORGAN STANLEY	0.92%	517.51K	34.08M	55.18K	+11.94%
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	2.56%	1.44M	94.75M	-400.85K	-21.79%
Jun 30, 2025	ALPS ADVISORS INC	0.05%	29.66K	1.95M	29.66K	+100.00%
Jun 30, 2025	NEA MANAGEMENT COMPANY, LLC	6.66%	3.75M	246.63M	0	0
Jun 30, 2025	PARADIGM BIOCAPITAL ADVISORS LP	8.27%	4.65M	306.14M	156.98K	+3.49%
Jun 30, 2025	ALLIANCEBERNSTEIN L.P.	0.09%	48.16K	3.17B	-3.14K	-6.12%
Jun 30, 2025	SAMSARA BIOCAPITAL, LLC	0.18%	101.46K	6.68M	-33.82K	-25.00%
Jun 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.13%	75.43K	4.97B	31.08K	+70.06%
Jun 30, 2025	UBS GROUP AG	0.26%	148.92K	9.81M	-60.66K	-28.94%
Jun 30, 2025	VESTAL POINT CAPITAL, LP	4.89%	2.75M	181.09M	362.28K	+15.17%
Jun 30, 2025	VANGUARD GROUP INC	7.02%	3.94M	259.77M	-40.27K	-1.01%
Jun 30, 2025	AMERICAN CENTURY COMPANIES INC	0.77%	431.47K	28.41M	377.15K	+694.29%
Jun 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.88%	495K	32.6M	-35K	-6.60%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.91%	510.61K	33.62M	335.82K	+192.13%
Jun 30, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	3.46%	1.94M	128M	278.59K	+16.73%
Jun 30, 2025	AJU IB INVESTMENT CO., LTD.	1.86%	1.05M	68.98M	0	0
Jun 30, 2025	ROCK SPRINGS CAPITAL MANAGEMENT LP	0.33%	186.31K	12.27M	186.31K	+100.00%
Jun 30, 2025	CITADEL ADVISORS LLC	0.35%	198.36K	13.06M	-527.76K	-72.68%
Jun 30, 2025	DEUTSCHE BANK AG\	0.59%	329.36K	21.69M	-14.33K	-4.17%
Jun 30, 2025	LORD, ABBETT & CO. LLC	0.6%	337.58K	22.23M	-326.95K	-49.20%
Jun 30, 2025	DIMENSIONAL FUND ADVISORS LP	0.61%	343.13K	22.59M	-143.14K	-29.44%
Jun 30, 2025	SCHONFELD STRATEGIC ADVISORS LLC	0.62%	346.73K	22.83M	113.21K	+48.48%
Jun 30, 2025	PICTET ASSET MANAGEMENT HOLDING SA	0.68%	383.14K	25.23M	377.65K	+6,882.61%
Jun 30, 2025	DECHENG CAPITAL LLC	0.97%	547.61K	4.46M	497.61K	+995.22%
Jun 30, 2025	CAPITAL WORLD INVESTORS	1.39%	783.01K	51.56M	73.64K	+10.38%
Jun 30, 2025	CORMORANT ASSET MANAGEMENT, LP	1.42%	800K	52.68M	-250K	-23.81%
Jun 30, 2025	BARCLAYS PLC	0.25%	139.38K	9.18M	61.74K	+79.52%
Jun 30, 2025	VICTORY CAPITAL MANAGEMENT INC	0.36%	199.74K	13.15M	21.63K	+12.14%
Jun 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.43%	241.41K	15.9M	222.97K	+1,209.23%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0.47%	262.36K	17.28M	98.69K	+60.30%
Jun 30, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.48%	267.11K	17.59M	2.36K	+0.89%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.71%	961.78K	63.34M	-58.76K	-5.76%
Jun 30, 2025	JPMORGAN CHASE & CO	1.74%	976.97K	64.33M	293.39K	+42.92%
Jun 30, 2025	JANUS HENDERSON GROUP PLC	1.82%	1.02M	67.39M	-486.91K	-32.24%
Jun 30, 2025	STATE STREET CORP	2.83%	1.59M	104.85M	-74.14K	-4.45%
Jun 30, 2025	SR ONE CAPITAL MANAGEMENT, LP	4.17%	2.35M	154.53M	0	0
Jun 30, 2025	PERCEPTIVE ADVISORS LLC	4.41%	2.48M	163.18M	-448.48K	-15.32%
Jun 30, 2025	FMR LLC	10.62%	5.97M	393.27M	-331.53K	-5.26%
Jun 30, 2025		0.16%	87.42K	5.76M	-24.37K	-21.80%
Jun 30, 2025	TREXQUANT INVESTMENT LP	0.08%	43.18K	2.84M	43.18K	+100.00%
Jun 30, 2025	EDMOND DE ROTHSCHILD HOLDING S.A.	0.08%	45.48K	2.99M	0	0
Mar 31, 2025	TD ASSET MANAGEMENT INC	0.3%	168.32K	11.04M	4.4K	+2.69%
Mar 31, 2025	STEMPOINT CAPITAL LP	0.5%	273.77K	17.96M	273.77K	+100.00%
Mar 31, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0.28%	152.02K	9.97M	-117.36K	-43.57%
Mar 31, 2025	BANK OF NEW YORK MELLON CORP	0.26%	143.62K	9.42M	-792	-0.55%
Mar 31, 2025	SAMSARA BIOCAPITAL, LLC	0.24%	135.28K	8.87M	-118.37K	-46.67%
Mar 31, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	3.01%	1.67M	109.23M	959.22K	+135.88%
Mar 31, 2025	IKARIAN CAPITAL, LLC	0.2%	111.6K	7.32M	111.6K	+100.00%
Mar 31, 2025		0.2%	111.79K	7.33M	111.79K	+100.00%
Mar 31, 2025	CAPTION MANAGEMENT, LLC	0.22%	121.2K	7.95M	-147.4K	-54.88%
Mar 31, 2025	DIMENSIONAL FUND ADVISORS LP	0.88%	486.27K	31.9M	181.18K	+59.39%
Mar 31, 2025	SOLEUS CAPITAL MANAGEMENT, L.P.	0.28%	153.03K	10.04M	32K	+26.44%
Mar 31, 2025	SCHONFELD STRATEGIC ADVISORS LLC	0.42%	233.52K	15.32M	200.79K	+613.33%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.32%	174.79K	11.47M	-115.22K	-39.73%
Mar 31, 2025	WOODLINE PARTNERS LP	0.3%	165.31K	10.84M	39.66K	+31.56%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0.3%	163.67K	10.74M	15.56K	+10.51%
Mar 31, 2025	FMR LLC	11.41%	6.3M	413.52M	-1.65M	-20.77%
Mar 31, 2025	PARADIGM BIOCAPITAL ADVISORS LP	8.13%	4.49M	294.68M	120.43K	+2.75%
Mar 31, 2025	CITADEL ADVISORS LLC	1.31%	726.13K	47.63M	700.9K	+2,778.49%
Mar 31, 2025	CAPITAL WORLD INVESTORS	1.28%	709.37K	46.53M	456.5K	+180.52%
Mar 31, 2025	JANUS HENDERSON GROUP PLC	2.73%	1.51M	102.64M	-46.6K	-2.99%
Mar 31, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.31%	173.06K	11.35M	18.66K	+12.08%
Mar 31, 2025	CORMORANT ASSET MANAGEMENT, LP	1.9%	1.05M	68.88M	-250K	-19.23%
Mar 31, 2025	AJU IB INVESTMENT CO., LTD.	1.9%	1.05M	68.72M	0	0
Mar 31, 2025	VANGUARD GROUP INC	7.21%	3.99M	261.43M	655.06K	+19.67%
Mar 31, 2025	BLACKROCK, INC.	7.18%	3.97M	260.27M	113.55K	+2.95%
Mar 31, 2025	NEA MANAGEMENT COMPANY, LLC	6.78%	3.75M	245.69M	0	0
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.85%	1.02M	66.96M	41.51K	+4.24%
Mar 31, 2025	JPMORGAN CHASE & CO	1.24%	683.58K	44.84M	459.13K	+204.55%
Mar 31, 2025	LORD, ABBETT & CO. LLC	1.2%	664.53K	43.59M	-310.31K	-31.83%
Mar 31, 2025	AFFINITY ASSET ADVISORS, LLC	0.96%	530K	34.77M	105K	+24.71%
Mar 31, 2025	BAMCO INC /NY/	0.85%	467.26K	30.65M	118.93K	+34.14%
Mar 31, 2025	MORGAN STANLEY	0.84%	462.33K	30.33M	-155.78K	-25.20%
Mar 31, 2025	NORTHERN TRUST CORP	0.73%	403.84K	26.49M	-6.89K	-1.68%
Mar 31, 2025	DEUTSCHE BANK AG\	0.62%	343.69K	22.55M	-835	-0.24%
Mar 31, 2025	RA CAPITAL MANAGEMENT, L.P.	5.5%	3.04M	199.2M	249.2K	+8.94%
Mar 31, 2025	PERCEPTIVE ADVISORS LLC	5.3%	2.93M	191.98M	-552.41K	-15.88%
Mar 31, 2025	SR ONE CAPITAL MANAGEMENT, LP	4.25%	2.35M	153.94M	0	0
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.61%	336.95K	22.1M	-6.14K	-1.79%
Mar 31, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.5%	277.1K	18.18M	140.9K	+103.45%
Mar 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	3.33%	1.84M	120.68M	-281.7K	-13.28%
Mar 31, 2025	STATE STREET CORP	3.02%	1.67M	109.32M	-108.92K	-6.14%
Mar 31, 2025	GILEAD SCIENCES, INC.	12.16%	6.72M	440.88M	0	0
Mar 31, 2025	VESTAL POINT CAPITAL, LP	4.32%	2.39M	156.63M	1.91M	+402.68%
Mar 31, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.48%	264.76K	17.37M	-2.63K	-0.98%
Mar 31, 2025	ARTIA GLOBAL PARTNERS LP	0.41%	229.09K	15.03M	-700	-0.30%
Mar 31, 2025	UBS GROUP AG	0.38%	209.57K	13.75M	2.03K	+0.98%
Mar 31, 2025	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.36%	200K	13.12M	200K	+100.00%
Mar 31, 2025	VICTORY CAPITAL MANAGEMENT INC	0.32%	178.11K	11.68M	-6.07K	-3.30%
Mar 31, 2025	RAYMOND JAMES FINANCIAL INC	0.23%	128.78K	8.45M	-1.82K	-1.40%
Mar 31, 2024	FEDERATED HERMES, INC.	0.44%	231.66K	16.11M	17.06K	+7.95%
Mar 31, 2024	SQUAREPOINT OPS LLC	0.23%	121.01K	8.42M	-8.15K	-6.31%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.23%	121.06K	8.42M	-10.87K	-8.24%
Mar 31, 2024	RAFFERTY ASSET MANAGEMENT, LLC	0.24%	126.75K	8.82M	14.8K	+13.22%
Mar 31, 2024	STEMPOINT CAPITAL LP	0.27%	140.27K	9.76M	-173.34K	-55.27%
Mar 31, 2024	SOLEUS CAPITAL MANAGEMENT, L.P.	0.29%	150K	10.43M	-9K	-5.66%
Mar 31, 2024	TWO SIGMA INVESTMENTS, LP	0.36%	188.85K	13.13M	43.58K	+30.00%
Mar 31, 2024	RUSSELL INVESTMENTS GROUP, LTD.	0.37%	195.44K	13.59M	5.9K	+3.11%
Mar 31, 2024	CANDRIAM S.C.A.	0.42%	220.01K	15.3M	-62.01K	-21.99%
Mar 31, 2024	EAGLE ASSET MANAGEMENT INC	0.43%	224.53K	15.04M	224.53K	+100.00%
Mar 31, 2024	VICTORY CAPITAL MANAGEMENT INC	0.45%	235.87K	16.4M	80.21K	+51.53%
Mar 31, 2024	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.49%	255K	17.74M	95K	+59.38%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.22%	114.8K	7.98M	106.2K	+1,234.88%
Mar 31, 2024	CUTTER CAPITAL MANAGEMENT, LP	0.2%	107K	7.44M	107K	+100.00%
Mar 31, 2024	WOODLINE PARTNERS LP	0.2%	104.06K	7.24M	0	0
Mar 31, 2024	UBS GROUP AG	0.2%	103.48K	7.2M	6.44K	+6.63%
Mar 31, 2024	JANUS HENDERSON GROUP PLC	2.91%	1.52M	105.86M	-15.9K	-1.03%
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	2.57%	1.34M	93.51M	84.37K	+6.70%
Mar 31, 2024	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	1.88%	982.86K	68.36M	60.46K	+6.56%
Mar 31, 2024	MORGAN STANLEY	1.33%	696.76K	48.46M	23.48K	+3.49%
Mar 31, 2024	FMR LLC	10.32%	5.39M	375.19M	1.02M	+23.19%
Mar 31, 2024	BLACKROCK INC.	5.86%	3.07M	213.25M	47.53K	+1.57%
Mar 31, 2024	SR ONE CAPITAL MANAGEMENT, LP	4.49%	2.35M	163.21M	-800K	-25.42%
Mar 31, 2024	VANGUARD GROUP INC	4.26%	2.23M	155.02M	167.04K	+8.10%
Mar 31, 2024	LORD, ABBETT & CO. LLC	2.29%	1.2M	83.33M	1.55K	+0.13%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.79%	414.54K	28.83M	220.25K	+113.37%
Mar 31, 2024	NORTHERN TRUST CORP	0.69%	359.46K	25M	-3.96K	-1.09%
Mar 31, 2024	GREAT POINT PARTNERS LLC	0.57%	300K	20.87M	251.74K	+521.58%
Mar 31, 2024	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.52%	272.01K	18.92M	-60.9K	-18.29%
Mar 31, 2024	BAMCO INC /NY/	0.48%	248.99K	17.32M	185.49K	+292.12%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.36%	186.78K	12.99M	-92.84K	-33.20%
Mar 31, 2024	PARKMAN HEALTHCARE PARTNERS LLC	0.3%	156.6K	10.89M	-11.66K	-6.93%
Mar 31, 2024	CITIGROUP INC	0.22%	114.95K	7.99M	62.62K	+119.65%
Mar 31, 2024	UBS ASSET MANAGEMENT AMERICAS INC	0.51%	265.41K	18.46M	135.27K	+103.95%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.52%	272.79K	18.97M	-82.9K	-23.31%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.54%	282.01K	19.61M	17.83K	+6.75%
Mar 31, 2024	AFFINITY ASSET ADVISORS, LLC	0.57%	300K	20.87M	-40K	-11.76%
Mar 31, 2024	PFM HEALTH SCIENCES, LP	0.58%	303.21K	21.09M	-31.99K	-9.54%
Mar 31, 2024	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.69%	363.09K	25.25M	127.33K	+54.01%
Mar 31, 2024	VOYA INVESTMENT MANAGEMENT LLC	0.73%	380.32K	26.45M	298.85K	+366.81%
Mar 31, 2024	DEUTSCHE BANK AG\	0.86%	447.78K	31.14M	308.6K	+221.71%
Mar 31, 2024	SAMSARA BIOCAPITAL, LLC	0.87%	453.64K	31.55M	-6.8K	-1.48%
Mar 31, 2024	JPMORGAN CHASE & CO	1.06%	551.75K	38.37M	-50.16K	-8.33%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	1.6%	838.47K	58.32M	53.07K	+6.76%
Mar 31, 2024	SUVRETTA CAPITAL MANAGEMENT, LLC	2.99%	1.56M	108.66M	-873.62K	-35.86%
Mar 31, 2024	CORMORANT ASSET MANAGEMENT, LP	3.4%	1.78M	123.8M	80K	+4.71%
Mar 31, 2024	STATE STREET CORP	3.61%	1.89M	131.11M	111.28K	+6.27%
Mar 31, 2024	NEA MANAGEMENT COMPANY, LLC	7.16%	3.75M	260.48M	0	0
Mar 31, 2024	PARADIGM BIOCAPITAL ADVISORS LP	7.3%	3.82M	265.55M	159.47K	+4.36%
Mar 31, 2024	MOODY ALDRICH PARTNERS LLC	0.04%	20.56K	1.43M	20.56K	+100.00%
Mar 31, 2024	FORA CAPITAL, LLC	0.04%	22.22K	1.55M	0	0
Mar 31, 2024	MARTINGALE ASSET MANAGEMENT L P	0.04%	22.93K	1.59M	-4.2K	-15.49%
Mar 31, 2024	CONGRESS ASSET MANAGEMENT CO /MA	0.04%	23.23K	1.62M	-1.83K	-7.31%
Mar 31, 2024	STATE OF WISCONSIN INVESTMENT BOARD	0.05%	26.63K	1.85M	-4.76K	-15.15%
Mar 31, 2024	ALGERT GLOBAL LLC	0.05%	28.31K	1.97M	19.12K	+208.05%
Mar 31, 2024	LEGAL & GENERAL GROUP PLC	0.06%	29.34K	2.04B	-418	-1.40%
Mar 31, 2024	DEKABANK DEUTSCHE GIROZENTRALE	0.06%	30K	2.11M	0	0
Mar 31, 2024	MYDA ADVISORS LLC	0.07%	35K	2.43M	-5K	-12.50%
Mar 31, 2024	PRINCIPAL FINANCIAL GROUP INC	0.07%	36.84K	2.56M	26.2K	+246.26%
Mar 31, 2024	ALPS ADVISORS INC	0.07%	37.24K	2.59M	4.83K	+14.92%
Mar 31, 2024	CREDIT SUISSE AG/	0.07%	38.74K	2.69M	1.56K	+4.18%
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	0.08%	39.58K	2.75M	2.58K	+6.97%
Mar 31, 2024	FIRST TRUST ADVISORS LP	0.08%	40.28K	2.8M	14.77K	+57.92%
Mar 31, 2024	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.09%	45.7K	3.18M	8.72K	+23.57%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.09%	47.2K	3.28M	1.75K	+3.84%
Mar 31, 2024	RHUMBLINE ADVISERS	0.1%	53K	3.69M	1.57K	+3.05%
Mar 31, 2024	FRANKLIN RESOURCES INC	0.1%	54.34K	3.78M	36.1K	+197.86%
Mar 31, 2024	SWISS NATIONAL BANK	0.11%	56.4K	3.92M	-800	-1.40%
Mar 31, 2024	EAM INVESTORS, LLC	0.13%	66.05K	4.59M	1K	+1.54%
Mar 31, 2024	THRIVENT FINANCIAL FOR LUTHERANS	0.13%	67.54K	4.7M	67.54K	+100.00%
Mar 31, 2024	TD ASSET MANAGEMENT INC	0.17%	89.92K	6.25B	8.6K	+10.58%
Mar 31, 2024	VESTAL POINT CAPITAL, LP	0.19%	100K	6.96M	40K	+66.67%
Mar 31, 2024	QUBE RESEARCH & TECHNOLOGIES LTD	0.19%	101.19K	7.04M	87.26K	+626.65%
Mar 31, 2024	PERCEPTIVE ADVISORS LLC	7.52%	3.93M	273.58M	-611.25K	-13.45%
Dec 31, 2023	FMR LLC	9.04%	4.38M	243.04M	-158.18K	-3.49%
Dec 31, 2023	VOYA INVESTMENT MANAGEMENT LLC	0.17%	81.47K	4.52M	24.32K	+42.55%
Dec 31, 2023	JANE STREET GROUP, LLC	0.17%	84.39K	4.68M	74.49K	+752.00%
Dec 31, 2023	UBS GROUP AG	0.2%	97.05K	5.39M	47.61K	+96.32%
Dec 31, 2023	WOODLINE PARTNERS LP	0.21%	104.06K	5.78M	104.06K	+100.00%
Dec 31, 2023	RAFFERTY ASSET MANAGEMENT, LLC	0.23%	111.95K	6.21M	-46.83K	-29.49%
Dec 31, 2023	PERCEPTIVE ADVISORS LLC	9.38%	4.54M	252.24M	578.83K	+14.59%
Dec 31, 2023	WALLEYE CAPITAL LLC	0.24%	118.34K	6.57M	-97.94K	-45.28%
Dec 31, 2023	CAAS CAPITAL MANAGEMENT LP	0.26%	124.96K	6.94M	0	0
Dec 31, 2023	CUBIST SYSTEMATIC STRATEGIES, LLC	0.26%	127.06K	7.05M	127.06K	+100.00%
Dec 31, 2023	SQUAREPOINT OPS LLC	0.27%	129.16K	7.17M	129.16K	+100.00%
Dec 31, 2023	BARCLAYS PLC	0.27%	129.43K	7.18M	43.24K	+50.17%
Dec 31, 2023	UBS ASSET MANAGEMENT AMERICAS INC	0.27%	130.14K	7.22M	-55.46K	-29.88%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.27%	131.93K	7.32M	14.67K	+12.51%
Dec 31, 2023	DEUTSCHE BANK AG\	0.29%	139.19K	7.72M	120.1K	+629.11%
Dec 31, 2023	TWO SIGMA INVESTMENTS, LP	0.3%	145.27K	8.06M	3.18K	+2.24%
Dec 31, 2023	VICTORY CAPITAL MANAGEMENT INC	0.32%	155.65K	8.64M	126K	+424.96%
Dec 31, 2023	SOLEUS CAPITAL MANAGEMENT, L.P.	0.33%	159K	8.82M	-484.78K	-75.30%
Dec 31, 2023	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	0.33%	160K	8.88M	160K	+100.00%
Dec 31, 2023	PARKMAN HEALTHCARE PARTNERS LLC	0.35%	168.26K	9.34M	-35.22K	-17.31%
Dec 31, 2023	RUSSELL INVESTMENTS GROUP, LTD.	0.39%	189.54K	10.52M	11.2K	+6.28%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.4%	194.29K	10.78M	84.84K	+77.52%
Dec 31, 2023	FEDERATED HERMES, INC.	0.44%	214.6K	11.91M	143.21K	+200.61%
Dec 31, 2023	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.49%	235.76K	13.08M	132.71K	+128.78%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.55%	264.18K	14.66M	3.72K	+1.43%
Dec 31, 2023	NUVEEN ASSET MANAGEMENT, LLC	0.58%	279.63K	15.52M	35.43K	+14.51%
Dec 31, 2023	CANDRIAM S.C.A.	0.58%	282.01K	15.65M	-116.01K	-29.15%
Dec 31, 2023		0.65%	313.6K	17.41M	313.6K	+100.00%
Dec 31, 2023	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.69%	332.9K	18.48M	-60K	-15.27%
Dec 31, 2023	PFM HEALTH SCIENCES, LP	0.69%	335.2K	18.6M	94.86K	+39.47%
Dec 31, 2023	AFFINITY ASSET ADVISORS, LLC	0.7%	340K	18.87M	-60K	-15.00%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.73%	355.69K	19.74M	-519.17K	-59.34%
Dec 31, 2023	NORTHERN TRUST CORP	0.75%	363.42K	20.17M	-4.03K	-1.10%
Dec 31, 2023	SAMSARA BIOCAPITAL, LLC	0.95%	460.44K	25.55M	-153.48K	-25.00%
Dec 31, 2023	JPMORGAN CHASE & CO	1.24%	601.91K	33.41M	38.01K	+6.74%
Dec 31, 2023	MORGAN STANLEY	1.39%	673.29K	37.37M	568.03K	+539.65%
Dec 31, 2023	DEEP TRACK CAPITAL, LP	1.5%	725.15K	40.25M	725.15K	+100.00%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.62%	785.4K	43.59M	46.35K	+6.27%
Dec 31, 2023	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	1.9%	922.4K	51.19M	12.22K	+1.34%
Dec 31, 2023	LORD, ABBETT & CO. LLC	2.47%	1.2M	66.41M	98.53K	+8.97%
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	2.6%	1.26M	69.94M	323.31K	+34.51%
Dec 31, 2023	JANUS HENDERSON GROUP PLC	3.18%	1.54M	85.39M	-237.23K	-13.36%
Dec 31, 2023	CORMORANT ASSET MANAGEMENT, LP	3.51%	1.7M	94.35M	-450K	-20.93%
Dec 31, 2023	STATE STREET CORP	3.66%	1.77M	98.45M	-240.41K	-11.94%
Dec 31, 2023	VANGUARD GROUP INC	4.26%	2.06M	114.43M	23.26K	+1.14%
Dec 31, 2023	SUVRETTA CAPITAL MANAGEMENT, LLC	5.03%	2.44M	135.2M	-433.99K	-15.12%
Dec 31, 2023	BLACKROCK INC.	6.23%	3.02M	167.53M	310.88K	+11.48%
Dec 31, 2023	SR ONE CAPITAL MANAGEMENT, LP	6.5%	3.15M	174.64M	-800K	-20.27%
Dec 31, 2023	PARADIGM BIOCAPITAL ADVISORS LP	7.55%	3.66M	203.05M	705.5K	+23.89%
Dec 31, 2023	NEA MANAGEMENT COMPANY, LLC	7.73%	3.75M	207.86M	0	0
Sep 30, 2023	MORGAN STANLEY	0.22%	105.26K	-	-173.85K	-62.29%
Sep 30, 2023	TWO SIGMA INVESTMENTS, LP	0.3%	142.1K	-	-184K	-56.42%
Sep 30, 2023	RAFFERTY ASSET MANAGEMENT, LLC	0.33%	158.78K	-	14.68K	+10.19%
Sep 30, 2023	RUSSELL INVESTMENTS GROUP, LTD.	0.37%	178.34K	-	62K	+53.29%
Sep 30, 2023	UBS ASSET MANAGEMENT AMERICAS INC	0.39%	185.59K	-	168.99K	+1,018.03%
Sep 30, 2023	WALLEYE CAPITAL LLC	0.45%	216.27K	-	-1.36K	-0.63%
Sep 30, 2023	NUVEEN ASSET MANAGEMENT, LLC	0.51%	244.19K	-	7.13K	+3.01%
Sep 30, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.54%	260.46K	-	19.52K	+8.10%
Sep 30, 2023	NORTHERN TRUST CORP	0.76%	367.45K	-	7.9K	+2.20%
Sep 30, 2023		0.81%	388.12K	-	388.12K	+100.00%
Sep 30, 2023	CANDRIAM S.C.A.	0.83%	398.02K	-	0	0
Sep 30, 2023	VIVO CAPITAL, LLC	1.05%	503.57K	-	69.78K	+16.09%
Sep 30, 2023	SOLEUS CAPITAL MANAGEMENT, L.P.	1.34%	643.78K	-	-358.22K	-35.75%
Sep 30, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.54%	739.05K	-	53.83K	+7.86%
Sep 30, 2023	GOLDMAN SACHS GROUP INC	1.82%	874.86K	-	-144.06K	-14.14%
Sep 30, 2023	NOVO HOLDINGS A/S	2.23%	1.08M	-	75K	+7.50%
Sep 30, 2023	LORD, ABBETT & CO. LLC	2.28%	1.1M	-	-167.34K	-13.22%
Sep 30, 2023	CORMORANT ASSET MANAGEMENT, LP	4.47%	2.15M	-	150K	+7.50%
Sep 30, 2023	BLACKROCK INC.	5.63%	2.71M	-	105.18K	+4.04%
Sep 30, 2023	PARADIGM BIOCAPITAL ADVISORS LP	6.14%	2.95M	-	606.12K	+25.83%
Sep 30, 2023	NEA MANAGEMENT COMPANY, LLC	7.79%	3.75M	-	0	0
Sep 30, 2023	SR ONE CAPITAL MANAGEMENT, LP	8.2%	3.95M	-	0	0
Sep 30, 2023	PERCEPTIVE ADVISORS LLC	8.24%	3.97M	-	-50.42K	-1.26%
Sep 30, 2023	STRS OHIO	0.06%	29.48K	-	23.28K	+375.50%
Sep 30, 2023	VICTORY CAPITAL MANAGEMENT INC	0.06%	29.65K	-	-12.06K	-28.91%
Sep 30, 2023	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.07%	33.18K	-	-9.69K	-22.59%
Sep 30, 2023	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0.07%	33.82K	-	-52.19K	-60.68%
Sep 30, 2023	CREDIT SUISSE AG/	0.07%	34.48K	-	-474	-1.36%
Sep 30, 2023	ALPS ADVISORS INC	0.07%	35.71K	-	432	+1.22%
Sep 30, 2023	ALLIANCEBERNSTEIN L.P.	0.08%	36.21K	-	0	0
Sep 30, 2023	WELLS FARGO & COMPANY/MN	0.08%	36.66K	-	-3.87K	-9.54%
Sep 30, 2023	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.08%	37.95K	-	37.95K	+100.00%
Sep 30, 2023	PUTNAM INVESTMENTS LLC	0.09%	41.26K	-	-356	-0.86%
Sep 30, 2023	TWO SIGMA ADVISERS, LP	0.09%	41.7K	-	-88.1K	-67.87%
Sep 30, 2023	UBS GROUP AG	0.1%	49.43K	-	-72.08K	-59.32%
Sep 30, 2023	BAMCO INC /NY/	0.1%	50K	-	10K	+25.00%
Sep 30, 2023	FMR LLC	9.43%	4.54M	-	-153.65K	-3.28%
Sep 30, 2023	RHUMBLINE ADVISERS	0.11%	51.35K	-	923	+1.83%
Sep 30, 2023	SCHONFELD STRATEGIC ADVISORS LLC	0.12%	56.36K	-	7.1K	+14.41%
Sep 30, 2023	VOYA INVESTMENT MANAGEMENT LLC	0.12%	57.15K	-	169	+0.30%
Sep 30, 2023	SWISS NATIONAL BANK	0.13%	63.3K	-	11.2K	+21.50%
Sep 30, 2023	HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND	0.13%	64K	-	64K	+100.00%
Sep 30, 2023	CITIGROUP INC	0.14%	69.02K	-	5.62K	+8.86%
Sep 30, 2023	FEDERATED HERMES, INC.	0.15%	71.39K	-	-93.28K	-56.65%
Sep 30, 2023	HIGHVISTA STRATEGIES LLC	0.16%	78.03K	-	15.16K	+24.11%
Sep 30, 2023	TD ASSET MANAGEMENT INC	0.17%	81.6K	-	52.8K	+183.33%
Sep 30, 2023	BARCLAYS PLC	0.18%	86.19K	-	10.59K	+14.01%
Sep 30, 2023	CLOUGH CAPITAL PARTNERS L P	0.21%	102.76K	-	-3.1K	-2.93%
Sep 30, 2023	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.21%	103.05K	-	-171.52K	-62.47%
Sep 30, 2023	BANK OF NEW YORK MELLON CORP	0.24%	117.27K	-	-13.26K	-10.16%

Insiders

Insiders	Designation	Shares Held
NEW ENTERPRISE ASSOCIATES 15, L.P.	10 percent owner	6.75M
NOVO HOLDINGS A/S	10 percent owner	4.02M
SR ONE CAPITAL MANAGEMENT, LLC	10 percent owner	1.66M
CARROLL JILL	director	1.48M
ELGHANDOUR RAMI	SEE REMARKS	149.19K
GILSON MICHELLE	CHIEF FINANCIAL OFFICER	8.47K
HEERY CHRISTOPHER	CHIEF MEDICAL OFFICER	284
WARE OLIVIA C	director	0
PATEL KAVITA	director	0
SANDELL SCOTT D	director	0
MAKHZOUMI MOHAMAD	director	0
FLORENCE ANTHONY A. JR.	director	0
BASKETT FOREST	director	0

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Nov 17, 2025	HEERY CHRISTOPHER	SALE	90.00	340	30.6K	284
Oct 15, 2025	GILSON MICHELLE	SALE	91.04	5.36K	488.32K	8.47K
Oct 06, 2025	GILSON MICHELLE	SALE	86.22	1.06K	91.73K	13.83K
Oct 03, 2025	GILSON MICHELLE	SALE	86.00	4.88K	419.87K	14.89K
Sep 30, 2025	HEERY CHRISTOPHER	SALE	82.20	1.53K	125.76K	624
Sep 29, 2025	HEERY CHRISTOPHER	SALE	80.16	73	5.85K	21.66K
Sep 26, 2025	HEERY CHRISTOPHER	SALE	80.12	12.4K	993.16K	21.73K
Sep 19, 2025	HEERY CHRISTOPHER	SALE	80.00	300	24K	34.13K
Sep 18, 2025	HEERY CHRISTOPHER	SALE	80.01	3.34K	267.47K	34.43K
Jun 10, 2025	PATEL KAVITA	SALE	67.36	1.5K	101.04K	0
May 27, 2025	GILSON MICHELLE	SALE	64.38	8.45K	543.91K	19.78K
May 20, 2025	PATEL KAVITA	SALE	58.43	1.5K	87.65K	0
Apr 29, 2025	PATEL KAVITA	SALE	64.20	1.5K	96.3K	0
Apr 08, 2025	PATEL KAVITA	SALE	57.50	1.5K	86.25K	0
Mar 18, 2025	PATEL KAVITA	SALE	71.64	1.5K	107.46K	0
Feb 26, 2025	ELGHANDOUR RAMI	SALE	62.69	10.89K	682.62K	149.19K
Feb 25, 2025	PATEL KAVITA	SALE	63.16	1.5K	94.74K	0
Feb 24, 2025	HEERY CHRISTOPHER	SALE	64.88	208	13.49K	37.49K
Feb 04, 2025	PATEL KAVITA	SALE	64.57	1.5K	96.86K	0
Jan 14, 2025	PATEL KAVITA	SALE	67.32	300	20.2K	0
Jan 08, 2025	GILSON MICHELLE	SALE	73.69	4K	294.55K	9.58K
Jan 08, 2025	ELGHANDOUR RAMI	SALE	73.69	13.84K	1.02M	117.28K
Jan 08, 2025	HEERY CHRISTOPHER	SALE	73.69	3.55K	261.83K	25.09K
Jan 07, 2025	GILSON MICHELLE	SALE	75.53	4.76K	359.51K	13.58K
Jan 07, 2025	ELGHANDOUR RAMI	SALE	75.53	16.47K	1.24M	131.11K
Jan 07, 2025	HEERY CHRISTOPHER	SALE	75.53	4.23K	319.48K	28.64K
Jan 06, 2025	GILSON MICHELLE	SALE	77.17	5.62K	433.75K	27.59K
Jan 06, 2025	HEERY CHRISTOPHER	SALE	77.17	2.98K	229.57K	32.87K
Jan 06, 2025	ELGHANDOUR RAMI	SALE	77.17	15.11K	1.17M	147.59K
Jan 03, 2025	HEERY CHRISTOPHER	SALE	79.55	2.98K	236.66K	35.84K
Jan 03, 2025	GILSON MICHELLE	SALE	79.55	5.62K	447.22K	33.21K
Jan 03, 2025	ELGHANDOUR RAMI	SALE	79.55	15.11K	1.2M	162.7K
Dec 24, 2024	PATEL KAVITA	SALE	77.61	100	7.76K	0
Dec 03, 2024	PATEL KAVITA	SALE	96.05	300	28.81K	0
Nov 15, 2024	GILSON MICHELLE	SALE	95.00	100	9.5K	0
Nov 12, 2024	PATEL KAVITA	SALE	106.33	1.5K	159.5K	0
Nov 11, 2024	PATEL KAVITA	SALE	106.91	3.01K	321.26K	0
Nov 08, 2024	GILSON MICHELLE	SALE	102.33	801	81.97K	1.76K
Nov 08, 2024	PATEL KAVITA	SALE	105.46	25.79K	2.72M	0
Nov 07, 2024	PATEL KAVITA	SALE	99.30	8.48K	841.86K	0
Oct 22, 2024	PATEL KAVITA	SALE	89.69	1.5K	134.54K	0
Oct 01, 2024	PATEL KAVITA	SALE	82.24	1.5K	123.36K	0
Sep 17, 2024	GILSON MICHELLE	SALE	77.88	8.73K	679.59K	6.92K
Sep 10, 2024	PATEL KAVITA	SALE	74.41	1.5K	111.62K	0
Sep 05, 2024	HEERY CHRISTOPHER	SALE	70.02	3.42K	239.53K	9.28K
Sep 03, 2024	HEERY CHRISTOPHER	SALE	70.07	2.9K	203.2K	9.28K
Aug 26, 2024	HEERY CHRISTOPHER	SALE	71.34	15.25K	1.09M	9.28K
Aug 20, 2024	PATEL KAVITA	SALE	65.88	1.5K	98.82K	0
Aug 16, 2024	HEERY CHRISTOPHER	SALE	65.05	5.45K	354.53K	9.28K
Aug 01, 2024	HEERY CHRISTOPHER	SALE	61.13	732	44.75K	9.28K
Jul 30, 2024	PATEL KAVITA	SALE	62.95	200	12.59K	0
Jul 16, 2024	HEERY CHRISTOPHER	SALE	65.30	10.9K	711.85K	9.28K
Jul 12, 2024	HEERY CHRISTOPHER	SALE	60.21	1.78K	107.18K	9.28K
Jul 11, 2024	HEERY CHRISTOPHER	SALE	60.01	3.67K	220.3K	9.28K
Jul 09, 2024	PATEL KAVITA	SALE	57.15	648	37.04K	0
Jul 01, 2024	HEERY CHRISTOPHER	SALE	56.20	2.78K	156.39K	9.28K
Jun 27, 2024	PATEL KAVITA	SALE	54.51	5.03K	274.11K	0
Jun 26, 2024	GILSON MICHELLE	SALE	54.25	551	29.89K	6.92K
Jun 12, 2024	HEERY CHRISTOPHER	SALE	56.03	82	4.59K	9.28K
May 24, 2024	GILSON MICHELLE	SALE	50.71	12.12K	614.66K	19.79K
May 01, 2024	HEERY CHRISTOPHER	SALE	53.55	100	5.36K	8.94K
Apr 16, 2024	WARE OLIVIA C	SALE	56.03	2.61K	146.35K	0
Apr 01, 2024	ELGHANDOUR RAMI	SALE	68.42	2.71K	185.48K	69.25K
Mar 26, 2024	HEERY CHRISTOPHER	SALE	70.19	861	60.43K	8.94K
Mar 22, 2024	HEERY CHRISTOPHER	SALE	72.25	1K	72.25K	8.94K
Mar 21, 2024	CARROLL JILL	SALE	70.55	504.26K	35.58M	1.48M
Mar 18, 2024	GILSON MICHELLE	SALE	69.73	3.04K	212.19K	9.49K
Mar 15, 2024	WARE OLIVIA C	SALE	70.99	3.34K	236.88K	0
Feb 12, 2024	ELGHANDOUR RAMI	SALE	64.46	11.17K	719.95K	92.34K
Feb 12, 2024	HEERY CHRISTOPHER	SALE	64.46	2.97K	191.25K	30.3K
Feb 09, 2024	ELGHANDOUR RAMI	SALE	63.40	13.89K	880.34K	103.51K
Feb 09, 2024	HEERY CHRISTOPHER	SALE	63.40	3.69K	233.81K	33.27K
Feb 08, 2024	ELGHANDOUR RAMI	SALE	62.29	13.01K	810.45K	117.39K
Feb 08, 2024	HEERY CHRISTOPHER	SALE	62.29	3.46K	215.29K	36.96K
Jan 04, 2024	ELGHANDOUR RAMI	SALE	55.27	29.07K	1.61M	60.19K
Jan 04, 2024	GILSON MICHELLE	SALE	55.27	8.51K	470.55K	16.31K
Jan 04, 2024	HEERY CHRISTOPHER	SALE	55.27	7.6K	419.93K	17.86K
Dec 18, 2023	HEERY CHRISTOPHER	SALE	51.86	845	43.82K	7.8K
Dec 14, 2023	CARROLL JILL	SALE	49.13	504.26K	24.77M	1.98M
Aug 04, 2023	HEERY CHRISTOPHER	SALE	35.38	3K	106.13K	7.8K
Jul 03, 2023	HEERY CHRISTOPHER	SALE	31.75	3K	95.25K	7.8K
Jun 01, 2023	CARROLL JILL	SALE	44.35	25.56K	1.13M	2.49M
May 31, 2023	ELGHANDOUR RAMI	SALE	44.27	2.6K	115.1K	36.17K
May 31, 2023	CARROLL JILL	SALE	41.50	315.16K	13.08M	2.51M
May 25, 2023	GILSON MICHELLE	SALE	42.77	6K	256.62K	9.49K
May 24, 2023	GILSON MICHELLE	SALE	41.64	150	6.25K	15.49K
May 11, 2023	SR ONE CAPITAL MANAGEMENT, LLC	SALE	46.15	3.8K	175.55K	1.66M
May 11, 2023	CARROLL JILL	SALE	46.15	6.49K	299.28K	2.83M
May 10, 2023	HEERY CHRISTOPHER	SALE	45.18	2.2K	99.27K	7.8K
May 09, 2023	HEERY CHRISTOPHER	SALE	45.00	500	22.5K	9.99K
May 05, 2023	HEERY CHRISTOPHER	SALE	45.00	1.2K	54K	10.49K
May 03, 2023	HEERY CHRISTOPHER	SALE	43.56	2.6K	113.24K	11.69K
Apr 24, 2023	HEERY CHRISTOPHER	SALE	40.00	20K	800.07K	11.69K
Apr 19, 2023	HEERY CHRISTOPHER	SALE	35.01	15.64K	547.66K	11.69K
Apr 18, 2023	HEERY CHRISTOPHER	SALE	35.00	6K	210K	14.99K
Apr 03, 2023	HEERY CHRISTOPHER	SALE	31.17	402	12.53K	15.59K
Feb 09, 2023	HEERY CHRISTOPHER	SALE	30.77	6.97K	214.33K	15.59K
Feb 09, 2023	ELGHANDOUR RAMI	SALE	30.77	31.44K	967.42K	38.77K
Feb 03, 2023	HEERY CHRISTOPHER	SALE	35.11	1.26K	44.07K	0
Jan 03, 2023	HEERY CHRISTOPHER	SALE	31.11	2.5K	77.78K	0
Dec 23, 2022	SANDELL SCOTT D	SALE	31.67	195	6.18K	0
Dec 22, 2022	BASKETT FOREST	SALE	31.45	1.63K	51.21K	0
Dec 21, 2022	MAKHZOUMI MOHAMAD	SALE	30.74	179	5.5K	0
Dec 21, 2022	FLORENCE ANTHONY A. JR.	SALE	30.74	179	5.5K	0
Dec 21, 2022	SANDELL SCOTT D	SALE	30.74	179	5.5K	0
Dec 13, 2022	HEERY CHRISTOPHER	SALE	30.03	12.5K	375.32K	0
Jun 21, 2022	NEW ENTERPRISE ASSOCIATES 15, L.P.	PURCHASE	16.00	312.5K	5M	6.75M
Jun 21, 2022	BASKETT FOREST	PURCHASE	16.00	312.5K	5M	6.75M
Feb 08, 2022	CARROLL JILL	PURCHASE	15.00	1.6M	24M	2.03M
Feb 08, 2022	SR ONE CAPITAL MANAGEMENT, LLC	PURCHASE	15.00	1.6M	24M	2.03M
Feb 08, 2022	NEW ENTERPRISE ASSOCIATES 15, L.P.	PURCHASE	15.00	1.58M	23.75M	6.43M
Feb 08, 2022	NOVO HOLDINGS A/S	PURCHASE	15.00	833.33K	12.5M	4.02M

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES29.29K9

NET SHARES-29.29K9

SHARES HELD150.04K9

% NET SHARES-119.52%0%

ACLX Stock Ownership Breakdown

Arcellx

Stock Outstanding Shares

Market Insider

Institutional Ownership

Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions

Stock Outstanding Shares

Market Insider

Institutional Ownership

Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions