Summary
• SELLAS Life Sciences’ stock rose 4.3% to $3.495 amid positive updates on the Phase 3 REGAL trial for Galinpepimut-S.
• The company reported a significant 132.6% stock increase over the past month and 222.1% year-to-date.
• Analysts maintain a “Buy” rating, reflecting confidence in SELLAS’s growth potential and clinical advancements.
SELLAS Life Sciences Group, Inc. (SLS) saw its stock price rise to $3.495, reflecting a 4.3% increase in intraday trading. This surge is notable given the company’s recent progress in clinical trials, despite there being some volatility in its overall price movements.
Trial Update Drives Investor Interest
The company’s recent update on December 29, 2025, regarding the ongoing Phase 3 REGAL trial evaluating Galinpepimut-S (GPS) as a potential maintenance therapy for patients with Acute Myeloid Leukemia (AML) after second complete remission (CR2) has captured investor attention. SELLAS highlighted its commitment to addressing critical needs in cancer treatment through this late-stage clinical trial.
The announcement aligns with the company’s strategic focus on novel therapies, helping to affirm its market position and potentially enhance its growth profile going forward.
Trading Setup: Technical Performance and Volatility
Technically, SLS’s stock exhibits a robust performance profile. The stock has experienced a remarkable 132.6% rise over the past month, corresponding with a 222.1% year-to-date increase. The current RSI level is high at 86.97, indicating a possible overbought condition, suggesting that traders should closely monitor the stock’s performance for potential corrections.
Additionally, SLS has shown significant volatility, with a weekly volatility of 10.1% and a monthly volatility of 9.7%. Average trading volumes have remained strong, with the recent session reporting a volume of 16,635,002 against a 10-day average of approximately 10,199,058.
Analyst Sentiment and Market Dynamics
SELLAS maintains a “Buy” rating from analysts, reflecting optimism surrounding its pipeline and potential market opportunities. The company has demonstrated a capacity to surprise positively in earnings, achieving a current surprise of 18.3% in its latest quarter, further fostering investor confidence.
With substantial advancements in its clinical trials and solid financial guidance, SELLAS appears well-positioned to navigate upcoming market activities effectively.
In conclusion, the surge in SELLAS Life Sciences’ stock price amid the recent trial update illustrates notable investor sentiment and a strong technical foundation, even as it navigates the complexities of biopharmaceutical development.


