How many institutions own XOMA stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own XOMA shares is 112, representing 73.35% of the company's common stock.

Who are the major shareholders selling XOMA Royalty Corp. stock?

BNP PARIBAS ARBITRAGE, SNC, in the last quarter, reduced its stake in XOMA by -33.29% restricting it's holding to 2.15 thousand shares of worth nearly $57.22K. RHUMBLINE ADVISERS also lessened -12.05% of the XOMA shares from its portfolio, reducing its holding to 11.58 thousand shares of worth $308.01K. BRIDGEWAY CAPITAL MANAGEMENT, LLC also shunned XOMA shares holding by -29.62% last quarter which brought its holding to 17.58 thousand shares worth $467.45K.

Investors who are buying XOMA stock?

As per its latest 13F filing, GEODE CAPITAL MANAGEMENT, LLC increased its stake in XOMA by 4.52% in the last quarter. The institutional holder raised its holding to 221.57 thousand shares having worth more than $5.89M. BLACKROCK, INC. also added 3.14% more shares of XOMA to its portfolio, raising its holding to 611.52 thousand shares of worth $16.26M. VANGUARD GROUP INC also increased its XOMA shares holding by 5.02% which brought its holding to 701.66 thousand shares worth $18.66M.

XOMA's major insiders: who are they?

The insider with the most stakes in XOMA is BVF PARTNERS L P/IL , 10 percent owner at the company. Additionally, XOMA stock is highly held by director PERRY MATTHEW D and Chief Executive Officer Hughes Owen among others.

Did an insider recently sell XOMA stock?

Company executives, directors, and other insiders own 4.01% percent of XOMA Royalty Corp.'s stock. Within the last six months, there have been 0 transaction(s) in which XOMA insiders have sold stock, totaling 0 shares. Insiders that have sold shares include BURNS THOMAS M., HUGHES OWEN, and BVF PARTNERS L P/IL.

Which insider recently purchased XOMA stock?

There have been 1 transaction(s) during the past 6-months in which XOMA Royalty Corp. insiders have bought stock, totalling 100000 shares

How much of XOMA does insiders own?

Around 102K XOMA Royalty Corp. shares are held by insiders, which represents about 4.01% of XOMA stock.

Who is the insider with the largest stake?

XOMA 10 percent owner, BVF PARTNERS L P/IL holds the largest portfolio of the company's shares. XOMA shares owned by BVF total nearly 1.27 million.

Which institution holds the most shares in XOMA?

BNP PARIBAS ARBITRAGE, SNC is the largest institutional owner in XOMA which holds 2.15 thousand shares worth $57.22K or 0.02% of the total XOMA shares outstanding followed by GEODE CAPITAL MANAGEMENT, LLC with ownership of 221.57 thousand shares representing 1.83% of the XOMA ownership. BLACKROCK, INC. is the third largest stakeholder with 611.52 thousand shares or 5.04% of the ownership worth more than $16.26M.

Is XOMA Royalty Corp. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the XOMA is concerned, it is a stock which is optionable.

Is there a short position on XOMA's shares?

Number of XOMA shares short is 264.42K. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding XOMA shares are there?

As of today, 12.09M shares of XOMA are outstanding.

Is there many float in XOMA stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, XOMA has 9.35M shares in float.

XOMA short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for XOMA is 5.18.

XOMA Royalty (XOMA) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares2.19

Short Percent Of Float2.93

Shares Outstanding12.09M

Shares Float9.35M

Shares Short264.42K

Short Ratio5.18

2.93%

Short % of Float

2.19%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

4.01% Percentage of Shares held by All Insiders

73.35% Percentage of Shares held by All Institutions

76.42% Percentage of Float held by Institutions

112

Number of Institutions Holding Shares

Institutional Ownership

About 73.35% of XOMA shares are held by financial institutions. BNP PARIBAS ARBITRAGE, SNC is the top corporate investor, holding 2.15K shares valued at $57.22K. A 0.02% stake in XOMA Royalty Corp. is owned by the company. GEODE CAPITAL MANAGEMENT, LLC owns 221.57K shares valued at $5.89M, which translates its holding of 1.83% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Dec 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.02%	2.15K	57.22K	-1.07K	-33.29%
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.83%	221.57K	5.89M	9.59K	+4.52%
Dec 31, 2025	BLACKROCK, INC.	5.04%	611.52K	16.26M	18.61K	+3.14%
Dec 31, 2025	VANGUARD GROUP INC	5.78%	701.66K	18.66M	33.55K	+5.02%
Dec 31, 2025	MORGAN STANLEY	14.13%	1.71M	45.59M	67.67K	+4.11%
Dec 31, 2025	SG AMERICAS SECURITIES, LLC	0.05%	6.36K	169K	6.36K	+100.00%
Dec 31, 2025	TWO SIGMA INVESTMENTS, LP	0.08%	9.72K	258.32K	9.72K	+100.00%
Dec 31, 2025	WELLS FARGO & COMPANY/MN	0.09%	10.76K	285.96K	4.28K	+66.05%
Dec 31, 2025	RHUMBLINE ADVISERS	0.1%	11.58K	308.01K	-1.59K	-12.05%
Dec 31, 2025	BANK OF AMERICA CORP /DE/	0.1%	11.94K	317.54K	7.99K	+201.95%
Dec 31, 2025	NUVEEN, LLC	0.1%	12.71K	337.85K	0	0
Dec 31, 2025	BARCLAYS PLC	0.12%	14.82K	394.12K	1.6K	+12.08%
Dec 31, 2025	NANO CAP NEW MILLENNIUM GROWTH FUND L P	0.12%	15K	398.85K	15K	+100.00%
Dec 31, 2025	GOLDMAN SACHS GROUP INC	0.13%	16.1K	428.02K	8.02K	+99.37%
Dec 31, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0%	469	12.47M	61	+14.95%
Dec 31, 2025	CITIGROUP INC	0%	555	14.76K	239	+75.63%
Dec 31, 2025		0.08%	10K	265.9K	10K	+100.00%
Dec 31, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.14%	17.58K	467.45K	-7.4K	-29.62%
Dec 31, 2025	LOS ANGELES CAPITAL MANAGEMENT LLC	0.16%	19.33K	642.21K	4.66K	+31.73%
Dec 31, 2025	PANAGORA ASSET MANAGEMENT INC	0.17%	21.23K	564.48K	4.14K	+24.19%
Dec 31, 2025	UBS GROUP AG	0.21%	26.05K	692.59K	21.9K	+527.49%
Dec 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.24%	29.38K	781.08K	0	0
Dec 31, 2025	RBF CAPITAL, LLC	0.25%	30K	797.7K	-616	-2.01%
Dec 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0.32%	39.02K	1.04M	10.12K	+35.01%
Dec 31, 2025	CM MANAGEMENT, LLC	0.33%	40K	1.06M	-8K	-16.67%
Dec 31, 2025	DIMENSIONAL FUND ADVISORS LP	0.36%	43.34K	1.15M	14.15K	+48.46%
Dec 31, 2025	TLS ADVISORS LLC	0.39%	47.92K	1.69M	-66.94K	-58.28%
Dec 31, 2025	BANK OF NEW YORK MELLON CORP	0.56%	68.38K	1.82M	7.03K	+11.46%
Dec 31, 2025	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0%	585	15.56K	2	+0.34%
Dec 31, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0.01%	778	20.69K	0	0
Dec 31, 2025	STATE STREET CORP	1.44%	174.91K	4.65M	7.87K	+4.71%
Dec 31, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.02%	2.36K	62.81K	0	0
Dec 31, 2025	MIRAE ASSET GLOBAL ETFS HOLDINGS LTD.	0.04%	4.5K	119.6K	186	+4.31%
Dec 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.24%	29.59K	786.83K	-3.03K	-9.27%
Dec 31, 2025	NORTHERN TRUST CORP	0.74%	90.4K	2.4M	-4.94K	-5.18%
Dec 31, 2025	HIGHVISTA STRATEGIES LLC	0.93%	112.92K	3M	7.2K	+6.81%
Dec 31, 2025	WOODLINE PARTNERS LP	2.17%	262.93K	6.99M	52.99K	+25.24%
Dec 31, 2025	OPALEYE MANAGEMENT INC.	2.41%	292.59K	7.78M	37.5K	+14.70%
Dec 31, 2025	FMR LLC	9.57%	1.16M	30.89M	87.56K	+8.15%
Dec 31, 2025	BVF INC/IL	21.34%	2.59M	68.88M	0	0
Dec 31, 2025	DEUTSCHE BANK AG\	0%	124	3.3K	-8.35K	-98.54%
Dec 31, 2025	CWM, LLC	0%	134	4K	-18	-11.84%
Dec 31, 2025	SIMPLEX TRADING, LLC	0%	173	4.6K	2	+1.17%
Dec 31, 2025	STERLING CAPITAL MANAGEMENT LLC	0%	233	6.2K	27	+13.11%
Dec 31, 2025	TRUVESTMENTS CAPITAL LLC	0%	290	7.71K	0	0
Dec 31, 2025	AMALGAMATED BANK	0%	298	8K	51	+20.65%
Dec 31, 2025	FEDERATED HERMES, INC.	0%	335	8.91K	108	+47.58%
Dec 31, 2025	COSTELLO ASSET MANAGEMENT, INC	0%	600	15.95K	0	0
Dec 31, 2025	AMERITAS INVESTMENT PARTNERS, INC.	0.01%	959	25.5K	0	0
Dec 31, 2025	LEGAL & GENERAL GROUP PLC	0.01%	976	25.95K	0	0
Dec 31, 2025	STATE OF ALASKA, DEPARTMENT OF REVENUE	0.01%	1.05K	27K	1.05K	+100.00%
Dec 31, 2025	ROTHSCHILD INVESTMENT LLC	0%	3	80	0	0
Dec 31, 2025	ALLWORTH FINANCIAL LP	0%	10	266	10	+100.00%
Dec 31, 2025	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0.02%	2.86K	75.94K	0	0
Dec 31, 2025	ADVISOR GROUP HOLDINGS, INC.	0.03%	3.54K	94.23K	-10	-0.28%
Dec 31, 2025	JPMORGAN CHASE & CO	0.03%	3.84K	101.97K	39	+1.03%
Dec 31, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.05%	5.68K	150.95K	0	0
Dec 31, 2025	SBI SECURITIES CO., LTD.	0%	12	319	-1	-7.69%
Dec 31, 2025	NISA INVESTMENT ADVISORS, LLC	0%	19	505	0	0
Dec 31, 2025	PNC FINANCIAL SERVICES GROUP, INC.	0%	25	666	18	+257.14%
Dec 31, 2025	EVERSOURCE WEALTH ADVISORS, LLC	0%	69	1.84K	-10	-12.66%
Dec 31, 2025	GAMMA INVESTING LLC	0%	113	3.01K	11	+10.78%
Dec 31, 2025	ROYAL BANK OF CANADA	0.01%	1.24K	33K	-285	-18.65%
Dec 31, 2025	SQUAREPOINT OPS LLC	0.07%	8.9K	236.68K	8.9K	+100.00%
Dec 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.08%	9.59K	255.08K	9.59K	+100.00%
Dec 31, 2025	STONEPINE CAPITAL MANAGEMENT, LLC	0.95%	115K	3.06M	-459	-0.40%
Dec 31, 2025	NATIXIS	0%	372	9.89K	0	0
Sep 30, 2025	MARSHALL WACE, LLP	0%	0	-	-16.31K	-100.00%
Sep 30, 2025	GROUP ONE TRADING, L.P.	0%	0	-	-900	-100.00%
Sep 30, 2025	TD WATERHOUSE CANADA INC.	0%	1	39	0	0
Sep 30, 2025	TORTOISE INVESTMENT MANAGEMENT, LLC	0%	2	77	2	+100.00%
Sep 30, 2025	TRUE WEALTH DESIGN, LLC	0%	3	116	0	0
Sep 30, 2025	ROTHSCHILD INVESTMENT LLC	0%	3	116	0	0
Sep 30, 2025	PNC FINANCIAL SERVICES GROUP, INC.	0%	7	271	5	+250.00%
Sep 30, 2025	SBI SECURITIES CO., LTD.	0%	13	501	1	+8.33%
Sep 30, 2025	NISA INVESTMENT ADVISORS, LLC	0%	19	732	0	0
Sep 30, 2025	QUADRANT CAPITAL GROUP LLC	0%	35	1.35K	35	+100.00%
Sep 30, 2025	EVERSOURCE WEALTH ADVISORS, LLC	0%	79	3.05K	0	0
Sep 30, 2025	GAMMA INVESTING LLC	0%	102	3.93K	0	0
Sep 30, 2025	STATE STREET CORP	1.39%	167.04K	6.44M	13.55K	+8.83%
Sep 30, 2025	WOODLINE PARTNERS LP	1.75%	209.95K	8.09M	29.72K	+16.49%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.77%	211.98K	8.17M	8.38K	+4.11%
Sep 30, 2025	OPALEYE MANAGEMENT INC.	2.12%	255.09K	9.83M	0	0
Sep 30, 2025	OPTIVER HOLDING B.V.	0%	150	5.78K	150	+100.00%
Sep 30, 2025	CWM, LLC	0%	152	6K	32	+26.67%
Sep 30, 2025	SIMPLEX TRADING, LLC	0%	171	6K	171	+100.00%
Sep 30, 2025	STERLING CAPITAL MANAGEMENT LLC	0%	206	7.94K	112	+119.15%
Sep 30, 2025	FEDERATED HERMES, INC.	0%	227	8.75K	227	+100.00%
Sep 30, 2025	AMALGAMATED BANK	0%	247	10K	0	0
Sep 30, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.05%	5.68K	218.79K	377	+7.11%
Sep 30, 2025	MAN GROUP PLC	0.05%	6.4K	246.54K	6.4K	+100.00%
Sep 30, 2025	NUVEEN, LLC	0.11%	12.71K	489.69K	0	0
Sep 30, 2025	RHUMBLINE ADVISERS	0.11%	13.17K	507.6K	-78	-0.59%
Sep 30, 2025	BARCLAYS PLC	0.11%	13.22K	509.65K	-3.42K	-20.53%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.24%	29.38K	1.13M	3K	+11.37%
Sep 30, 2025	NORTHERN TRUST CORP	0.79%	95.34K	3.67M	1.12K	+1.19%
Sep 30, 2025	HIGHVISTA STRATEGIES LLC	0.88%	105.71K	4.07M	-8.83K	-7.71%
Sep 30, 2025	TLS ADVISORS LLC	0.96%	114.87K	3.79M	-4.18K	-3.51%
Sep 30, 2025	LEGAL & GENERAL GROUP PLC	0.01%	976	37.62K	0	0
Sep 30, 2025	PANAGORA ASSET MANAGEMENT INC	0.14%	17.09K	658.8K	-1.29K	-6.99%
Sep 30, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.21%	24.98K	962.73K	-1.22K	-4.66%
Sep 30, 2025	JANE STREET GROUP, LLC	0.23%	27.36K	1.05M	27.36K	+100.00%
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.24%	28.9K	1.11M	17K	+142.86%
Sep 30, 2025	RBF CAPITAL, LLC	0.26%	30.62K	1.18M	0	0
Sep 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.27%	32.62K	1.26M	32.62K	+100.00%
Sep 30, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0%	408	15.72K	-1.87K	-82.05%
Sep 30, 2025	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0%	583	22.47K	1	+0.17%
Sep 30, 2025	COSTELLO ASSET MANAGEMENT, INC	0.01%	600	23.12K	0	0
Sep 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0.01%	778	29.98K	756	+3,436.36%
Sep 30, 2025	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0.02%	2.86K	110.07K	1.24K	+76.95%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.03%	3.23K	124.33K	2.35K	+266.59%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0.05%	6.48K	249.6K	1.09K	+20.23%
Sep 30, 2025	STATE OF WISCONSIN INVESTMENT BOARD	0.11%	13.57K	523.03K	13.57K	+100.00%
Sep 30, 2025	LOS ANGELES CAPITAL MANAGEMENT LLC	0.12%	14.68K	565.61K	0	0
Sep 30, 2025	DIMENSIONAL FUND ADVISORS LP	0.24%	29.19K	1.12M	1.27K	+4.55%
Sep 30, 2025	CM MANAGEMENT, LLC	0.4%	48K	1.85M	-16K	-25.00%
Sep 30, 2025	BLACKROCK, INC.	4.94%	592.9K	22.85M	1.23K	+0.21%
Sep 30, 2025	VANGUARD GROUP INC	5.56%	668.11K	25.75M	29.3K	+4.59%
Sep 30, 2025	FMR LLC	8.95%	1.07M	41.4M	-5.26K	-0.49%
Sep 30, 2025	MORGAN STANLEY	13.72%	1.65M	63.48M	102.03K	+6.60%
Sep 30, 2025	BVF INC/IL	21.57%	2.59M	99.83M	0	0
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.51%	61.35K	2.36M	1.56K	+2.61%
Sep 30, 2025	STONEPINE CAPITAL MANAGEMENT, LLC	0.96%	115.46K	4.45M	-36.68K	-24.11%
Sep 30, 2025	TRUVESTMENTS CAPITAL LLC	0%	290	11.18K	0	0
Sep 30, 2025	CITIGROUP INC	0%	316	12.18K	-3.4K	-91.49%
Sep 30, 2025	NATIXIS	0%	372	14.34K	-1.09K	-74.56%
Sep 30, 2025	CITADEL ADVISORS LLC	0.06%	7.58K	292.17K	7.58K	+100.00%
Sep 30, 2025	ROYAL BANK OF CANADA	0.01%	1.53K	59K	-3.1K	-67.00%
Sep 30, 2025	MACQUARIE GROUP LTD	0.06%	6.93K	221K	3.47K	+100.00%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	0.07%	8.07K	311.17K	8.07K	+100.00%
Sep 30, 2025	DEUTSCHE BANK AG\	0.07%	8.48K	326.67K	0	0
Sep 30, 2025	AMERITAS INVESTMENT PARTNERS, INC.	0.01%	959	36.96K	0	0
Sep 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.02%	2.36K	91.03K	0	0
Sep 30, 2025	ADVISOR GROUP HOLDINGS, INC.	0.03%	3.55K	116.6K	75	+2.16%
Sep 30, 2025	JPMORGAN CHASE & CO	0.03%	3.8K	146.3K	-644	-14.50%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.03%	3.96K	152.43K	-245	-5.83%
Sep 30, 2025	UBS GROUP AG	0.03%	4.15K	159.98K	-11.96K	-74.23%
Sep 30, 2025	MIRAE ASSET GLOBAL ETFS HOLDINGS LTD.	0.04%	4.31K	166.18K	-828	-16.11%
Sep 30, 2025	COVESTOR LTD	0%	0	-	-58	-100.00%
Jun 30, 2025	DIMENSIONAL FUND ADVISORS LP	0.23%	27.92K	705.79K	6.04K	+27.60%
Jun 30, 2025	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0%	582	14.67M	0	0
Jun 30, 2025	TD WATERHOUSE CANADA INC.	0%	1	26	0	0
Jun 30, 2025	MARSHALL WACE, LLP	0.14%	16.31K	410.96K	1.78K	+12.21%
Jun 30, 2025	TRUVESTMENTS CAPITAL LLC	0%	290	7.31K	0	0
Jun 30, 2025	GAMMA INVESTING LLC	0%	102	2.57K	15	+17.24%
Jun 30, 2025	STERLING CAPITAL MANAGEMENT LLC	0%	94	2.37K	35	+59.32%
Jun 30, 2025	ACUITAS INVESTMENTS, LLC	0%	0	-	-5.67K	-100.00%
Jun 30, 2025	SQUAREPOINT OPS LLC	0%	0	-	-10.31K	-100.00%
Jun 30, 2025	EVERSEPT PARTNERS, LP	0%	0	-	-45.02K	-100.00%
Jun 30, 2025	COREBRIDGE FINANCIAL, INC.	0%	0	-	-3.98K	-100.00%
Jun 30, 2025	BVF INC/IL	21.57%	2.59M	65.28M	-392.72K	-13.17%
Jun 30, 2025	BLACKROCK, INC.	4.93%	591.67K	14.91M	58.89K	+11.05%
Jun 30, 2025	MORGAN STANLEY	12.87%	1.54M	38.93M	422.68K	+37.66%
Jun 30, 2025	FMR LLC	8.99%	1.08M	27.21M	-8.78K	-0.81%
Jun 30, 2025	TLS ADVISORS LLC	0.99%	119.04K	3M	0	0
Jun 30, 2025	HIGHVISTA STRATEGIES LLC	0.95%	114.55K	2.89M	0	0
Jun 30, 2025	RBF CAPITAL, LLC	0.26%	30.62K	771.52K	0	0
Jun 30, 2025	EVERSOURCE WEALTH ADVISORS, LLC	0%	79	1.99K	79	+100.00%
Jun 30, 2025	COVESTOR LTD	0%	58	1K	58	+100.00%
Jun 30, 2025	ROTHSCHILD INVESTMENT LLC	0%	3	76	0	0
Jun 30, 2025	TRUE WEALTH DESIGN, LLC	0%	3	76	0	0
Jun 30, 2025	OPALEYE MANAGEMENT INC.	2.12%	255.09K	6.43M	2.04K	+0.81%
Jun 30, 2025	WOODLINE PARTNERS LP	1.5%	180.23K	4.54M	11.68K	+6.93%
Jun 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.02%	2.36K	59.52K	0	0
Jun 30, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0.02%	2.27K	57.28K	1.52K	+203.07%
Jun 30, 2025		0.01%	1.61K	40.67K	0	0
Jun 30, 2025	NATIXIS	0.01%	1.46K	36.84K	-62	-4.07%
Jun 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.01%	880	22.18K	418	+90.48%
Jun 30, 2025	COSTELLO ASSET MANAGEMENT, INC	0.01%	600	15.12K	0	0
Jun 30, 2025	STONEPINE CAPITAL MANAGEMENT, LLC	1.27%	152.14K	3.83M	22.33K	+17.20%
Jun 30, 2025	CM MANAGEMENT, LLC	0.53%	64K	1.61M	0	0
Jun 30, 2025	LOS ANGELES CAPITAL MANAGEMENT LLC	0.12%	14.68K	369.84K	14.68K	+100.00%
Jun 30, 2025	MIRAE ASSET GLOBAL ETFS HOLDINGS LTD.	0.04%	5.14K	129.53K	270	+5.54%
Jun 30, 2025	LAZARD ASSET MANAGEMENT LLC	0.04%	4.82K	121K	4.82K	+100.00%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0.04%	4.2K	105.84K	-757	-15.27%
Jun 30, 2025	CITIGROUP INC	0.03%	3.71K	93.57K	-2.02K	-35.21%
Jun 30, 2025	MACQUARIE GROUP LTD	0.03%	3.47K	87K	0	0
Jun 30, 2025	ADVISOR GROUP HOLDINGS, INC.	0.03%	3.48K	87.67K	26	+0.75%
Jun 30, 2025	LEGAL & GENERAL GROUP PLC	0.01%	976	24.64K	124	+14.55%
Jun 30, 2025	AMERITAS INVESTMENT PARTNERS, INC.	0.01%	959	24.17K	355	+58.77%
Jun 30, 2025	GROUP ONE TRADING, L.P.	0.01%	900	22.68K	0	0
Jun 30, 2025	JPMORGAN CHASE & CO	0.04%	4.44K	111.89K	543	+13.93%
Jun 30, 2025	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0.01%	1.61K	40.67K	0	0
Jun 30, 2025	VANGUARD GROUP INC	5.32%	638.81K	16.1M	179.73K	+39.15%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.7%	203.6K	5.13M	16.93K	+9.07%
Jun 30, 2025	STATE STREET CORP	1.28%	153.48K	3.87M	8.76K	+6.05%
Jun 30, 2025	NORTHERN TRUST CORP	0.78%	94.22K	2.37M	5.17K	+5.81%
Jun 30, 2025	BANK OF NEW YORK MELLON CORP	0.5%	59.79K	1.51M	1.88K	+3.24%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.22%	26.38K	664.65K	3.22K	+13.89%
Jun 30, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.22%	26.2K	660.24K	0	0
Jun 30, 2025	OCCUDO QUANTITATIVE STRATEGIES LP	0.17%	20.93K	1.3K	20.93K	+100.00%
Jun 30, 2025	PANAGORA ASSET MANAGEMENT INC	0.15%	18.38K	463.15K	18.38K	+100.00%
Jun 30, 2025	BARCLAYS PLC	0.14%	16.64K	420K	7.74K	+87.05%
Jun 30, 2025	UBS GROUP AG	0.13%	16.11K	405.97K	11.28K	+233.33%
Jun 30, 2025	RHUMBLINE ADVISERS	0.11%	13.25K	333.87K	2.02K	+17.98%
Jun 30, 2025	DEUTSCHE BANK AG\	0.07%	8.48K	213.6K	2.04K	+31.76%
Jun 30, 2025	NUVEEN, LLC	0.11%	12.71K	320.19K	-1.66K	-11.54%
Jun 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.1%	11.9K	299.88K	-1.8K	-13.14%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.1%	11.56K	291.29K	1.31K	+12.73%
Jun 30, 2025	WELLS FARGO & COMPANY/MN	0.04%	5.39K	135.74K	841	+18.50%
Jun 30, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.04%	5.3K	133.56K	929	+21.25%
Jun 30, 2025	ROYAL BANK OF CANADA	0.04%	4.63K	117K	-1.12K	-19.48%
Jun 30, 2025	RAYMOND JAMES FINANCIAL INC	0.04%	4.6K	115.92K	4.6K	+100.00%
Mar 31, 2025	RBF CAPITAL, LLC	0.26%	30.62K	610.18K	0	0
Mar 31, 2025	EVERSEPT PARTNERS, LP	0.38%	45.02K	897.19K	-50.4K	-52.82%
Mar 31, 2025	STATE STREET CORP	1.21%	144.73K	2.88M	200	+0.14%
Mar 31, 2025	WOODLINE PARTNERS LP	1.41%	168.55K	3.36M	12.28K	+7.86%
Mar 31, 2025	OPALEYE MANAGEMENT INC.	2.11%	253.04K	5.04M	3.04K	+1.22%
Mar 31, 2025	FMR LLC	9.09%	1.09M	21.69M	-1.68K	-0.15%
Mar 31, 2025	MORGAN STANLEY	9.38%	1.12M	22.37M	804.97K	+253.68%
Mar 31, 2025	BVF INC/IL	24.92%	2.98M	59.45M	-650.72K	-17.91%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.1%	11.52K	229.65K	-9.45K	-45.05%
Mar 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0.11%	13.7K	273.04K	-2.4K	-14.91%
Mar 31, 2025	JPMORGAN CHASE & CO	0.03%	3.9K	77.67K	-8.19K	-67.76%
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	0.12%	14.05K	280.1K	14.05K	+100.00%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.19%	23.16K	461.54K	45	+0.19%
Mar 31, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.22%	26.2K	522.17K	700	+2.75%
Mar 31, 2025	BANK OF NEW YORK MELLON CORP	0.48%	57.91K	1.15M	366	+0.64%
Mar 31, 2025	LEGAL & GENERAL GROUP PLC	0.01%	852	16.98K	0	0
Mar 31, 2025		0.01%	1.61K	32.17K	0	0
Mar 31, 2025	ADVISOR GROUP HOLDINGS, INC.	0.03%	3.45K	68.81K	100	+2.98%
Mar 31, 2025	MACQUARIE GROUP LTD	0.03%	3.47K	69M	0	0
Mar 31, 2025	COREBRIDGE FINANCIAL, INC.	0.03%	3.98K	79.4K	-8	-0.20%
Mar 31, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.04%	4.37K	87.11K	0	0
Mar 31, 2025	WELLS FARGO & COMPANY/MN	0.04%	4.55K	90.6K	246	+5.72%
Mar 31, 2025	UBS GROUP AG	0.04%	4.83K	96.32K	-1.9K	-28.19%
Mar 31, 2025	SQUAREPOINT OPS LLC	0.09%	10.31K	205.42K	823	+8.68%
Mar 31, 2025	MARSHALL WACE, LLP	0.12%	14.53K	289.64K	14.53K	+100.00%
Mar 31, 2025	DIMENSIONAL FUND ADVISORS LP	0.18%	21.88K	436.11K	-532	-2.37%
Mar 31, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.02%	2.36K	47K	0	0
Mar 31, 2025	TLS ADVISORS LLC	0.99%	119.04K	2.37M	0	0
Mar 31, 2025	HIGHVISTA STRATEGIES LLC	0.96%	114.55K	2.28M	0	0
Mar 31, 2025	NORTHERN TRUST CORP	0.74%	89.05K	1.77M	-2.13K	-2.33%
Mar 31, 2025	CM MANAGEMENT, LLC	0.53%	64K	1.28M	9K	+16.36%
Mar 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.09%	10.25K	204.36K	10.25K	+100.00%
Mar 31, 2025	CITADEL ADVISORS LLC	0.08%	9.64K	192.09K	-1.91K	-16.55%
Mar 31, 2025	BARCLAYS PLC	0.07%	8.9K	177K	-3.89K	-30.41%
Mar 31, 2025	DEUTSCHE BANK AG\	0.05%	6.43K	128.21K	6.31K	+5,087.90%
Mar 31, 2025	ROYAL BANK OF CANADA	0.05%	5.75K	114K	-289	-4.79%
Mar 31, 2025	CITIGROUP INC	0.05%	5.73K	114.22K	-611	-9.63%
Mar 31, 2025	ACUITAS INVESTMENTS, LLC	0.05%	5.67K	113.08K	-55.03K	-90.65%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0.04%	4.96K	98.79K	-2.84K	-36.42%
Mar 31, 2025	MIRAE ASSET GLOBAL ETFS HOLDINGS LTD.	0.04%	4.87K	97.06K	234	+5.05%
Mar 31, 2025	NATIXIS	0.01%	1.52K	30.16K	-202	-11.70%
Mar 31, 2025	GROUP ONE TRADING, L.P.	0.01%	900	17.94K	500	+125.00%
Mar 31, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0.01%	750	14.95K	296	+65.20%
Mar 31, 2025	AMERITAS INVESTMENT PARTNERS, INC.	0.01%	604	12.04K	0	0
Mar 31, 2025	STONEPINE CAPITAL MANAGEMENT, LLC	1.08%	129.81K	2.59M	4.11K	+3.27%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.56%	186.67K	3.72M	4.48K	+2.46%
Mar 31, 2025	VANGUARD GROUP INC	3.84%	459.09K	9.15M	-4.75K	-1.02%
Mar 31, 2025	BLACKROCK, INC.	4.45%	532.79K	10.62M	-6.14K	-1.14%
Mar 31, 2025	RHUMBLINE ADVISERS	0.09%	11.23K	223.81K	165	+1.49%
Mar 31, 2024	TLS ADVISORS LLC	1.05%	120.37K	2.9M	-100	-0.08%
Mar 31, 2024	NELSON, VAN DENBURG & CAMPBELL WEALTH MANAGEMENT GROUP, LLC	0%	501	12.05K	0	0
Mar 31, 2024	LEGAL & GENERAL GROUP PLC	0%	531	12.77K	-176	-24.89%
Mar 31, 2024	CWM, LLC	0.01%	587	14K	2	+0.34%
Mar 31, 2024	GLOBAL RETIREMENT PARTNERS, LLC	0.01%	600	14.43K	0	0
Mar 31, 2024	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0.01%	735	17.68K	-468	-38.90%
Mar 31, 2024	ROYAL BANK OF CANADA	0.01%	1.12K	27K	-3.38K	-75.04%
Mar 31, 2024	CITIGROUP INC	0.01%	1.37K	32.97K	327	+31.32%
Mar 31, 2024	CITADEL ADVISORS LLC	0.01%	1.7K	40.89K	-700	-29.17%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.03%	3.92K	94.35K	-6.69K	-63.03%
Mar 31, 2024	METLIFE INVESTMENT MANAGEMENT, LLC	0.03%	3.96K	95.24K	3.96K	+100.00%
Mar 31, 2024	DEUTSCHE BANK AG\	0.04%	4.64K	111.5K	-172	-3.58%
Mar 31, 2024	FIRST MANHATTAN CO. LLC.	0.04%	5K	120.25K	0	0
Mar 31, 2024	BARCLAYS PLC	0.05%	5.16K	124K	-4.93K	-48.84%
Mar 31, 2024	KNOTT DAVID M JR	0.17%	19.72K	474K	0	0
Mar 31, 2024	DIMENSIONAL FUND ADVISORS LP	0.22%	25.52K	613.66K	0	0
Mar 31, 2024	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.23%	26.4K	634.92K	-200	-0.75%
Mar 31, 2024	RBF CAPITAL, LLC	0.27%	30.62K	736.32K	-2.39K	-7.24%
Mar 31, 2024	CM MANAGEMENT, LLC	0.48%	55K	1.32M	0	0
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.53%	60.69K	1.46M	-1.9K	-3.04%
Mar 31, 2024	WOODLINE PARTNERS LP	0.63%	72.11K	1.73M	21.55K	+42.62%
Mar 31, 2024	NEW YORK STATE COMMON RETIREMENT FUND	0.05%	5.64K	136K	376	+7.15%
Mar 31, 2024	UBS GROUP AG	0.06%	7.36K	176.89K	-590	-7.43%
Mar 31, 2024	NORTHERN TRUST CORP	0.75%	86.1K	2.07M	-872	-1.00%
Mar 31, 2024	EVERSEPT PARTNERS, LP	0.85%	97.07K	2.33M	3.34K	+3.56%
Mar 31, 2024	HIGHVISTA STRATEGIES LLC	1.04%	118.9K	2.86M	0	0
Mar 31, 2024	ACUITAS INVESTMENTS, LLC	1.07%	123.2K	2.96M	-13.94K	-10.16%
Mar 31, 2024	STATE STREET CORP	1.21%	138.95K	3.34M	14.53K	+11.67%
Mar 31, 2024	MORGAN STANLEY	1.39%	159.18K	3.83M	143.64K	+923.88%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	1.48%	170.05K	4.09M	9.11K	+5.66%
Mar 31, 2024	OPALEYE MANAGEMENT INC.	2.18%	250K	6.01M	0	0
Mar 31, 2024	STONEPINE CAPITAL MANAGEMENT, LLC	2.21%	253.77K	6.1M	3.77K	+1.51%
Mar 31, 2024	VANGUARD GROUP INC	3.53%	405.53K	9.75M	-15.94K	-3.78%
Mar 31, 2024	RHUMBLINE ADVISERS	0.07%	8.36K	201.07K	204	+2.50%
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	0.08%	8.78K	212K	8.78K	+100.00%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.09%	9.99K	240.21K	9.99K	+100.00%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.13%	15.4K	370.37K	15.4K	+100.00%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.17%	19.56K	470.42K	0	0
Mar 31, 2024	BLACKROCK INC.	4.19%	480.51K	11.56M	-7.98K	-1.63%
Mar 31, 2024	FMR LLC	10.11%	1.16M	27.91M	5.57K	+0.48%
Mar 31, 2024	BVF INC/IL	31.66%	3.63M	87.39M	0	0
Mar 31, 2024	AMERITAS INVESTMENT PARTNERS, INC.	0.01%	604	14.53K	0	0
Mar 31, 2024	NATIXIS	0.02%	1.73K	41.51K	0	0
Mar 31, 2024	WELLS FARGO & COMPANY/MN	0.02%	2.78K	66.8K	333	+13.62%
Mar 31, 2024	JPMORGAN CHASE & CO	0.03%	3.23K	77.75K	-1.76K	-35.24%
Mar 31, 2024	MACQUARIE GROUP LTD	0.03%	3.47K	83K	0	0
Mar 31, 2024	BNP PARIBAS ARBITRAGE, SNC	0.03%	3.54K	85.21K	1.27K	+55.60%
Mar 31, 2024	AMERICAN INTERNATIONAL GROUP, INC.	0.03%	3.6K	86.65K	-31	-0.85%
Mar 31, 2024	METROPOLITAN LIFE INSURANCE CO/NY	0%	411	9.89K	411	+100.00%
Mar 31, 2024	TD WATERHOUSE CANADA INC.	0%	0	-	-1	-100.00%
Mar 31, 2024	AJOVISTA, LLC	0%	0	-	-1.16K	-100.00%
Mar 31, 2024	SCARBOROUGH ADVISORS, LLC	0%	0	-	-175	-100.00%
Mar 31, 2024	RENAISSANCE TECHNOLOGIES LLC	0%	0	-	-12.3K	-100.00%
Mar 31, 2024	PNC FINANCIAL SERVICES GROUP, INC.	0%	2	48	0	0
Mar 31, 2024	NISA INVESTMENT ADVISORS, LLC	0%	8	192	0	0
Mar 31, 2024	ALLSPRING GLOBAL INVESTMENTS HOLDINGS, LLC	0%	15	360	0	0
Mar 31, 2024	ADVISOR GROUP HOLDINGS, INC.	0%	71	1.71K	1	+1.43%
Mar 31, 2024	GAMMA INVESTING LLC	0%	75	1.8K	67	+837.50%
Mar 31, 2024	AMALGAMATED BANK	0%	247	6K	-391	-61.29%
Mar 31, 2024	TRUVESTMENTS CAPITAL LLC	0%	400	9.62K	0	0
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.17%	19.56K	361.86K	0	0
Dec 31, 2023	KNOTT DAVID M JR	0.17%	19.72K	365K	0	0
Dec 31, 2023	DIMENSIONAL FUND ADVISORS LP	0.22%	25.52K	472.05K	-2.86K	-10.08%
Dec 31, 2023	CITADEL ADVISORS LLC	0.02%	2.4K	44.4K	-2.3K	-48.94%
Dec 31, 2023	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.23%	26.6K	492.1K	0	0
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	0.25%	28.3K	523.57K	274	+0.98%
Dec 31, 2023	RBF CAPITAL, LLC	0.29%	33.01K	610.59K	-1.78K	-5.12%
Dec 31, 2023	WOODLINE PARTNERS LP	0.44%	50.56K	935.34K	50.56K	+100.00%
Dec 31, 2023	CM MANAGEMENT, LLC	0.48%	55K	1.02M	55K	+100.00%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.55%	62.59K	1.16M	-70	-0.11%
Dec 31, 2023	NORTHERN TRUST CORP	0.76%	86.97K	1.61M	-240	-0.28%
Dec 31, 2023	EVERSEPT PARTNERS, LP	0.82%	93.73K	1.73M	3.78K	+4.20%
Dec 31, 2023		0.01%	1.16K	21.5K	1.16K	+100.00%
Dec 31, 2023	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0.01%	1.2K	22.26K	-410	-25.42%
Dec 31, 2023	RHUMBLINE ADVISERS	0.07%	8.16K	150.9K	-205	-2.45%
Dec 31, 2023	HIGHVISTA STRATEGIES LLC	1.04%	118.9K	2.2M	0	0
Dec 31, 2023	TLS ADVISORS LLC	1.05%	120.47K	2.23M	-200	-0.17%
Dec 31, 2023	STATE STREET CORP	1.08%	124.42K	2.3M	1.99K	+1.63%
Dec 31, 2023	ACUITAS INVESTMENTS, LLC	1.2%	137.13K	2.54M	0	0
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.4%	160.94K	2.98M	4.21K	+2.68%
Dec 31, 2023	OPALEYE MANAGEMENT INC.	2.18%	250K	4.63M	-24.5K	-8.93%
Dec 31, 2023	STONEPINE CAPITAL MANAGEMENT, LLC	2.18%	250K	4.63M	-186.6K	-42.74%
Dec 31, 2023	UBS GROUP AG	0.07%	7.95K	146.98K	3.97K	+99.87%
Dec 31, 2023	VANGUARD GROUP INC	3.67%	421.47K	7.8M	6.84K	+1.65%
Dec 31, 2023	BLACKROCK INC.	4.26%	488.49K	9.04M	31K	+6.78%
Dec 31, 2023	FMR LLC	10.07%	1.16M	21.37M	-29.01K	-2.45%
Dec 31, 2023	BVF INC/IL	31.67%	3.63M	67.22M	0	0
Dec 31, 2023	NATIXIS	0.02%	1.73K	31.93K	0	0
Dec 31, 2023	BNP PARIBAS ARBITRAGE, SNC	0.02%	2.28K	42.12K	1.23K	+118.31%
Dec 31, 2023	WELLS FARGO & COMPANY/MN	0.02%	2.45K	45.22K	445	+22.25%
Dec 31, 2023	MACQUARIE GROUP LTD	0.03%	3.47K	64K	0	0
Dec 31, 2023	AMERICAN INTERNATIONAL GROUP, INC.	0.03%	3.63K	67.23K	-15	-0.41%
Dec 31, 2023	ROYAL BANK OF CANADA	0.04%	4.5K	83K	2.31K	+105.62%
Dec 31, 2023	DEUTSCHE BANK AG\	0.04%	4.81K	88.95K	4.81K	+100.00%
Dec 31, 2023	JPMORGAN CHASE & CO	0.04%	4.99K	92.35K	-134	-2.61%
Dec 31, 2023	FIRST MANHATTAN CO. LLC.	0.04%	5K	92.5K	-2.5K	-33.33%
Dec 31, 2023	NEW YORK STATE COMMON RETIREMENT FUND	0.05%	5.26K	97K	-15	-0.28%
Dec 31, 2023	GLOBAL RETIREMENT PARTNERS, LLC	0.01%	600	11.85K	0	0
Dec 31, 2023	AMERITAS INVESTMENT PARTNERS, INC.	0.01%	604	11.17K	0	0
Dec 31, 2023	AMALGAMATED BANK	0.01%	638	12K	-73	-10.27%
Dec 31, 2023	TOWER RESEARCH CAPITAL LLC (TRC)	0.01%	651	12.04K	-131	-16.75%
Dec 31, 2023	LEGAL & GENERAL GROUP PLC	0.01%	707	13.08K	0	0
Dec 31, 2023	CITIGROUP INC	0.01%	1.04K	19.31K	1.04K	+26,000.00%
Dec 31, 2023	BARCLAYS PLC	0.09%	10.09K	187K	8.72K	+638.51%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.09%	10.61K	196.29K	4.38K	+70.36%
Dec 31, 2023	SQUAREPOINT OPS LLC	0.11%	12.27K	227.07K	12.27K	+100.00%
Dec 31, 2023	RENAISSANCE TECHNOLOGIES LLC	0.11%	12.3K	227K	-5.91K	-32.46%
Dec 31, 2023	MORGAN STANLEY	0.14%	15.55K	287.62K	9.55K	+159.03%

Insiders

Among the XOMA insiders holding of 4.01% of the stake in company, BVF PARTNERS L P/IL, 10 percent owner, holds the largest shares of 1.27M. PERRY MATTHEW D, director, is the second largest XOMA insider with ownership of 200K shares. HUGHES OWEN, Chief Executive Officer, stands third with possession of 102K shares of that stake.

Insiders	Designation	Shares Held
BVF PARTNERS L P/IL	10 percent owner	1.27M
PERRY MATTHEW D	director	200K
HUGHES OWEN	Chief Executive Officer	102K
BURNS THOMAS M.	SVP, Finance & CFO	30.08K
NEAL JAMES R	CEO	11.82K
LIMBER JOSEPH M	director	10K
SITKO BRADLEY	Chief Investment Officer	7.05K

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Dec 04, 2025	HUGHES OWEN	PURCHASE	25.05	100K	2.51M	102K
Sep 22, 2025	BURNS THOMAS M.	SALE	36.81	15	552.15	30.08K
Jun 30, 2025	SITKO BRADLEY	PURCHASE	25.39	2K	50.78K	7.05K
May 20, 2025	HUGHES OWEN	SALE	25.38	25.64K	650.67K	62.7K
May 20, 2025	BURNS THOMAS M.	SALE	25.38	10.48K	266.03K	22.56K
May 16, 2025	BVF PARTNERS L P/IL	SALE	27.10	265.32K	7.19M	1.27M
Apr 07, 2025	SITKO BRADLEY	PURCHASE	24.70	2K	49.4K	5.05K
Apr 07, 2025	LIMBER JOSEPH M	PURCHASE	25.60	5.24K	134.22K	10K
Apr 04, 2025	LIMBER JOSEPH M	PURCHASE	25.56	3.35K	85.52K	4.76K
Apr 03, 2025	LIMBER JOSEPH M	PURCHASE	25.44	1.41K	35.9K	1.41K
Apr 01, 2025	BURNS THOMAS M.	PURCHASE	25.46	1K	25.46K	2K
Mar 31, 2025	SITKO BRADLEY	PURCHASE	25.39	245	6.22K	3.05K
Mar 21, 2025	SITKO BRADLEY	PURCHASE	25.43	2.8K	71.2K	2.8K
Jan 24, 2025	BVF PARTNERS L P/IL	SALE	26.10	149.98K	3.91M	0
Jan 08, 2025	SITKO BRADLEY	PURCHASE	25.60	75	1.92K	75
Dec 31, 2024	SITKO BRADLEY	PURCHASE	25.90	300	7.77K	9.15K
Nov 13, 2024	BURNS THOMAS M.	SALE	29.94	9.78K	292.66K	14.55K
Nov 13, 2024	HUGHES OWEN	SALE	29.95	21.88K	655.34K	34.98K
Oct 03, 2023	SITKO BRADLEY	PURCHASE	13.89	250	3.47K	5.6K
Oct 02, 2023	HUGHES OWEN	PURCHASE	13.83	1K	13.83K	3.5K
Oct 02, 2023	SITKO BRADLEY	PURCHASE	14.25	1.5K	21.38K	5.35K
Sep 26, 2023	HUGHES OWEN	PURCHASE	14.43	2.5K	36.06K	2.5K
Sep 25, 2023	HUGHES OWEN	PURCHASE	14.65	1	14.65	1
May 31, 2023	SITKO BRADLEY	PURCHASE	17.00	500	8.5K	2.5K
May 24, 2023	HUGHES OWEN	PURCHASE	23.79	1.03K	24.55K	2K
May 23, 2023	SITKO BRADLEY	PURCHASE	19.00	850	16.15K	3.85K
May 23, 2023	HUGHES OWEN	PURCHASE	23.33	200	4.67K	200
May 19, 2023	SITKO BRADLEY	PURCHASE	19.50	1K	19.5K	3K
May 16, 2023	SITKO BRADLEY	PURCHASE	23.19	300	6.96K	1.8K
May 15, 2023	SITKO BRADLEY	PURCHASE	23.40	1.5K	35.1K	1.5K
May 12, 2023	SITKO BRADLEY	PURCHASE	18.66	43	802.38	43
Jan 06, 2023	BVF PARTNERS L P/IL	PURCHASE	21.98	1.57K	34.58K	1.62M
Jan 05, 2023	BVF PARTNERS L P/IL	PURCHASE	18.39	15.67K	288.1K	1.62M
Sep 27, 2022	BVF PARTNERS L P/IL	PURCHASE	16.89	678	11.45K	1.6M
Sep 26, 2022	BVF PARTNERS L P/IL	PURCHASE	16.83	3.02K	50.85K	1.6M
Sep 23, 2022	BVF PARTNERS L P/IL	PURCHASE	16.50	9.89K	163.07K	1.6M
Sep 16, 2022	BVF PARTNERS L P/IL	PURCHASE	17.89	10.9K	194.92K	1.59M
Sep 15, 2022	BVF PARTNERS L P/IL	PURCHASE	17.96	5.58K	100.14K	1.58M
Sep 14, 2022	BVF PARTNERS L P/IL	PURCHASE	17.25	26.44K	456.04K	1.57M
Jul 15, 2022	NEAL JAMES R	SALE	31.86	905	28.83K	11.82K
Jul 15, 2022	BURNS THOMAS M.	SALE	31.66	2K	63.32K	6.56K
Mar 23, 2022	NEAL JAMES R	SALE	30.02	1.11K	33.35K	11.82K
Mar 21, 2022	BURNS THOMAS M.	SALE	30.02	2.34K	70.21K	6.56K
Mar 21, 2022	NEAL JAMES R	SALE	29.00	50K	1.45M	11.82K
Jun 25, 2021	NEAL JAMES R	SALE	35.13	686	24.1K	11.82K
Mar 31, 2021	BVF PARTNERS L P/IL	SALE	38.36	84.25K	3.23M	75.29K
Dec 15, 2020	BURNS THOMAS M.	SALE	42.04	5.61K	235.74K	6.56K
Dec 15, 2020	NEAL JAMES R	SALE	42.04	5.71K	239.9K	20.85K
Dec 11, 2020	BVF PARTNERS L P/IL	PURCHASE	25.00	200K	5M	200K
Dec 11, 2020	PERRY MATTHEW D	PURCHASE	25.00	200K	5M	200K
Nov 23, 2020	NEAL JAMES R	SALE	32.96	13.13K	432.66K	20.85K
Nov 23, 2020	BURNS THOMAS M.	SALE	32.93	5.13K	168.75K	6.56K
Nov 20, 2020	NEAL JAMES R	SALE	33.35	426	14.21K	20.85K
Nov 20, 2020	BURNS THOMAS M.	SALE	33.35	426	14.21K	6.56K
Nov 05, 2020	NEAL JAMES R	SALE	27.50	727	19.99K	20.85K
Nov 05, 2020	BURNS THOMAS M.	SALE	27.50	726	19.97K	6.56K
Sep 23, 2020	BVF PARTNERS L P/IL	PURCHASE	18.20	7.2K	131.06K	1.75M
Sep 22, 2020	BVF PARTNERS L P/IL	PURCHASE	18.45	4.99K	92.06K	1.74M
Sep 21, 2020	BVF PARTNERS L P/IL	PURCHASE	18.39	10.07K	185.12K	1.74M
Sep 04, 2020	BVF PARTNERS L P/IL	PURCHASE	18.77	3.83K	71.89K	1.73M
Sep 01, 2020	BVF PARTNERS L P/IL	PURCHASE	18.87	7.67K	144.74K	1.72M
Aug 31, 2020	BVF PARTNERS L P/IL	PURCHASE	18.48	6.86K	126.81K	1.72M
Aug 28, 2020	BVF PARTNERS L P/IL	PURCHASE	19.17	922	17.68K	1.71M
Aug 25, 2020	BVF PARTNERS L P/IL	PURCHASE	19.75	2.24K	44.31K	1.71M
Aug 24, 2020	BVF PARTNERS L P/IL	PURCHASE	19.31	5.18K	100K	1.71M
Aug 21, 2020	BVF PARTNERS L P/IL	PURCHASE	19.32	1.61K	31.05K	1.7M
Aug 20, 2020	BVF PARTNERS L P/IL	PURCHASE	19.12	1.77K	33.88K	1.97M
Aug 19, 2020	BVF PARTNERS L P/IL	PURCHASE	19.70	3.5K	68.88K	1.97M
Aug 18, 2020	BVF PARTNERS L P/IL	PURCHASE	19.27	895	17.25K	1.96M
Aug 14, 2020	BVF PARTNERS L P/IL	PURCHASE	18.69	21.92K	409.81K	1.96M
Aug 13, 2020	BVF PARTNERS L P/IL	PURCHASE	17.80	1.05K	18.69K	1.94M
Aug 12, 2020	BVF PARTNERS L P/IL	PURCHASE	17.34	4.05K	70.23K	1.94M
Mar 25, 2020	BVF PARTNERS L P/IL	PURCHASE	17.20	8.26K	142.13K	1.28M
Mar 23, 2020	NEAL JAMES R	PURCHASE	14.50	1K	14.5K	20.85K
Mar 20, 2020	NEAL JAMES R	PURCHASE	16.41	1K	16.41K	19.85K
Mar 18, 2020	BVF PARTNERS L P/IL	PURCHASE	14.52	4.44K	64.47K	1.27M
Mar 17, 2020	BVF PARTNERS L P/IL	PURCHASE	15.73	8.11K	127.65K	1.27M
Mar 16, 2020	BVF PARTNERS L P/IL	PURCHASE	15.73	10.16K	159.92K	1.26M
Mar 13, 2020	BVF PARTNERS L P/IL	PURCHASE	18.34	100K	1.83M	1.25M
Dec 18, 2019	BVF PARTNERS L P/IL	PURCHASE	22.00	165.96K	3.65M	1.1M
Nov 06, 2019	NEAL JAMES R	SALE	22.00	4.35K	95.66K	17.67K
Sep 19, 2019	NEAL JAMES R	SALE	20.69	3.73K	77.13K	20.31K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE100K1

SALES00

NET SHARES100K1

SHARES HELD102K1

% NET SHARES-1.96%0%

Frequently Asked Questions

Stock Outstanding Shares

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares2.19

Short Percent Of Float2.93

Shares Outstanding12.09M

Shares Float9.35M

Shares Short264.42K

Short Ratio5.18

2.93%

Short % of Float

2.19%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

4.01% Percentage of Shares held by All Insiders

73.35% Percentage of Shares held by All Institutions

76.42% Percentage of Float held by Institutions

112

Number of Institutions Holding Shares

Institutional Ownership

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Dec 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.02%	2.15K	57.22K	-1.07K	-33.29%
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.83%	221.57K	5.89M	9.59K	+4.52%
Dec 31, 2025	BLACKROCK, INC.	5.04%	611.52K	16.26M	18.61K	+3.14%
Dec 31, 2025	VANGUARD GROUP INC	5.78%	701.66K	18.66M	33.55K	+5.02%
Dec 31, 2025	MORGAN STANLEY	14.13%	1.71M	45.59M	67.67K	+4.11%
Dec 31, 2025	SG AMERICAS SECURITIES, LLC	0.05%	6.36K	169K	6.36K	+100.00%
Dec 31, 2025	TWO SIGMA INVESTMENTS, LP	0.08%	9.72K	258.32K	9.72K	+100.00%
Dec 31, 2025	WELLS FARGO & COMPANY/MN	0.09%	10.76K	285.96K	4.28K	+66.05%
Dec 31, 2025	RHUMBLINE ADVISERS	0.1%	11.58K	308.01K	-1.59K	-12.05%
Dec 31, 2025	BANK OF AMERICA CORP /DE/	0.1%	11.94K	317.54K	7.99K	+201.95%
Dec 31, 2025	NUVEEN, LLC	0.1%	12.71K	337.85K	0	0
Dec 31, 2025	BARCLAYS PLC	0.12%	14.82K	394.12K	1.6K	+12.08%
Dec 31, 2025	NANO CAP NEW MILLENNIUM GROWTH FUND L P	0.12%	15K	398.85K	15K	+100.00%
Dec 31, 2025	GOLDMAN SACHS GROUP INC	0.13%	16.1K	428.02K	8.02K	+99.37%
Dec 31, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0%	469	12.47M	61	+14.95%
Dec 31, 2025	CITIGROUP INC	0%	555	14.76K	239	+75.63%
Dec 31, 2025		0.08%	10K	265.9K	10K	+100.00%
Dec 31, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.14%	17.58K	467.45K	-7.4K	-29.62%
Dec 31, 2025	LOS ANGELES CAPITAL MANAGEMENT LLC	0.16%	19.33K	642.21K	4.66K	+31.73%
Dec 31, 2025	PANAGORA ASSET MANAGEMENT INC	0.17%	21.23K	564.48K	4.14K	+24.19%
Dec 31, 2025	UBS GROUP AG	0.21%	26.05K	692.59K	21.9K	+527.49%
Dec 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.24%	29.38K	781.08K	0	0
Dec 31, 2025	RBF CAPITAL, LLC	0.25%	30K	797.7K	-616	-2.01%
Dec 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0.32%	39.02K	1.04M	10.12K	+35.01%
Dec 31, 2025	CM MANAGEMENT, LLC	0.33%	40K	1.06M	-8K	-16.67%
Dec 31, 2025	DIMENSIONAL FUND ADVISORS LP	0.36%	43.34K	1.15M	14.15K	+48.46%
Dec 31, 2025	TLS ADVISORS LLC	0.39%	47.92K	1.69M	-66.94K	-58.28%
Dec 31, 2025	BANK OF NEW YORK MELLON CORP	0.56%	68.38K	1.82M	7.03K	+11.46%
Dec 31, 2025	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0%	585	15.56K	2	+0.34%
Dec 31, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0.01%	778	20.69K	0	0
Dec 31, 2025	STATE STREET CORP	1.44%	174.91K	4.65M	7.87K	+4.71%
Dec 31, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.02%	2.36K	62.81K	0	0
Dec 31, 2025	MIRAE ASSET GLOBAL ETFS HOLDINGS LTD.	0.04%	4.5K	119.6K	186	+4.31%
Dec 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.24%	29.59K	786.83K	-3.03K	-9.27%
Dec 31, 2025	NORTHERN TRUST CORP	0.74%	90.4K	2.4M	-4.94K	-5.18%
Dec 31, 2025	HIGHVISTA STRATEGIES LLC	0.93%	112.92K	3M	7.2K	+6.81%
Dec 31, 2025	WOODLINE PARTNERS LP	2.17%	262.93K	6.99M	52.99K	+25.24%
Dec 31, 2025	OPALEYE MANAGEMENT INC.	2.41%	292.59K	7.78M	37.5K	+14.70%
Dec 31, 2025	FMR LLC	9.57%	1.16M	30.89M	87.56K	+8.15%
Dec 31, 2025	BVF INC/IL	21.34%	2.59M	68.88M	0	0
Dec 31, 2025	DEUTSCHE BANK AG\	0%	124	3.3K	-8.35K	-98.54%
Dec 31, 2025	CWM, LLC	0%	134	4K	-18	-11.84%
Dec 31, 2025	SIMPLEX TRADING, LLC	0%	173	4.6K	2	+1.17%
Dec 31, 2025	STERLING CAPITAL MANAGEMENT LLC	0%	233	6.2K	27	+13.11%
Dec 31, 2025	TRUVESTMENTS CAPITAL LLC	0%	290	7.71K	0	0
Dec 31, 2025	AMALGAMATED BANK	0%	298	8K	51	+20.65%
Dec 31, 2025	FEDERATED HERMES, INC.	0%	335	8.91K	108	+47.58%
Dec 31, 2025	COSTELLO ASSET MANAGEMENT, INC	0%	600	15.95K	0	0
Dec 31, 2025	AMERITAS INVESTMENT PARTNERS, INC.	0.01%	959	25.5K	0	0
Dec 31, 2025	LEGAL & GENERAL GROUP PLC	0.01%	976	25.95K	0	0
Dec 31, 2025	STATE OF ALASKA, DEPARTMENT OF REVENUE	0.01%	1.05K	27K	1.05K	+100.00%
Dec 31, 2025	ROTHSCHILD INVESTMENT LLC	0%	3	80	0	0
Dec 31, 2025	ALLWORTH FINANCIAL LP	0%	10	266	10	+100.00%
Dec 31, 2025	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0.02%	2.86K	75.94K	0	0
Dec 31, 2025	ADVISOR GROUP HOLDINGS, INC.	0.03%	3.54K	94.23K	-10	-0.28%
Dec 31, 2025	JPMORGAN CHASE & CO	0.03%	3.84K	101.97K	39	+1.03%
Dec 31, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.05%	5.68K	150.95K	0	0
Dec 31, 2025	SBI SECURITIES CO., LTD.	0%	12	319	-1	-7.69%
Dec 31, 2025	NISA INVESTMENT ADVISORS, LLC	0%	19	505	0	0
Dec 31, 2025	PNC FINANCIAL SERVICES GROUP, INC.	0%	25	666	18	+257.14%
Dec 31, 2025	EVERSOURCE WEALTH ADVISORS, LLC	0%	69	1.84K	-10	-12.66%
Dec 31, 2025	GAMMA INVESTING LLC	0%	113	3.01K	11	+10.78%
Dec 31, 2025	ROYAL BANK OF CANADA	0.01%	1.24K	33K	-285	-18.65%
Dec 31, 2025	SQUAREPOINT OPS LLC	0.07%	8.9K	236.68K	8.9K	+100.00%
Dec 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.08%	9.59K	255.08K	9.59K	+100.00%
Dec 31, 2025	STONEPINE CAPITAL MANAGEMENT, LLC	0.95%	115K	3.06M	-459	-0.40%
Dec 31, 2025	NATIXIS	0%	372	9.89K	0	0
Sep 30, 2025	MARSHALL WACE, LLP	0%	0	-	-16.31K	-100.00%
Sep 30, 2025	GROUP ONE TRADING, L.P.	0%	0	-	-900	-100.00%
Sep 30, 2025	TD WATERHOUSE CANADA INC.	0%	1	39	0	0
Sep 30, 2025	TORTOISE INVESTMENT MANAGEMENT, LLC	0%	2	77	2	+100.00%
Sep 30, 2025	TRUE WEALTH DESIGN, LLC	0%	3	116	0	0
Sep 30, 2025	ROTHSCHILD INVESTMENT LLC	0%	3	116	0	0
Sep 30, 2025	PNC FINANCIAL SERVICES GROUP, INC.	0%	7	271	5	+250.00%
Sep 30, 2025	SBI SECURITIES CO., LTD.	0%	13	501	1	+8.33%
Sep 30, 2025	NISA INVESTMENT ADVISORS, LLC	0%	19	732	0	0
Sep 30, 2025	QUADRANT CAPITAL GROUP LLC	0%	35	1.35K	35	+100.00%
Sep 30, 2025	EVERSOURCE WEALTH ADVISORS, LLC	0%	79	3.05K	0	0
Sep 30, 2025	GAMMA INVESTING LLC	0%	102	3.93K	0	0
Sep 30, 2025	STATE STREET CORP	1.39%	167.04K	6.44M	13.55K	+8.83%
Sep 30, 2025	WOODLINE PARTNERS LP	1.75%	209.95K	8.09M	29.72K	+16.49%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.77%	211.98K	8.17M	8.38K	+4.11%
Sep 30, 2025	OPALEYE MANAGEMENT INC.	2.12%	255.09K	9.83M	0	0
Sep 30, 2025	OPTIVER HOLDING B.V.	0%	150	5.78K	150	+100.00%
Sep 30, 2025	CWM, LLC	0%	152	6K	32	+26.67%
Sep 30, 2025	SIMPLEX TRADING, LLC	0%	171	6K	171	+100.00%
Sep 30, 2025	STERLING CAPITAL MANAGEMENT LLC	0%	206	7.94K	112	+119.15%
Sep 30, 2025	FEDERATED HERMES, INC.	0%	227	8.75K	227	+100.00%
Sep 30, 2025	AMALGAMATED BANK	0%	247	10K	0	0
Sep 30, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.05%	5.68K	218.79K	377	+7.11%
Sep 30, 2025	MAN GROUP PLC	0.05%	6.4K	246.54K	6.4K	+100.00%
Sep 30, 2025	NUVEEN, LLC	0.11%	12.71K	489.69K	0	0
Sep 30, 2025	RHUMBLINE ADVISERS	0.11%	13.17K	507.6K	-78	-0.59%
Sep 30, 2025	BARCLAYS PLC	0.11%	13.22K	509.65K	-3.42K	-20.53%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.24%	29.38K	1.13M	3K	+11.37%
Sep 30, 2025	NORTHERN TRUST CORP	0.79%	95.34K	3.67M	1.12K	+1.19%
Sep 30, 2025	HIGHVISTA STRATEGIES LLC	0.88%	105.71K	4.07M	-8.83K	-7.71%
Sep 30, 2025	TLS ADVISORS LLC	0.96%	114.87K	3.79M	-4.18K	-3.51%
Sep 30, 2025	LEGAL & GENERAL GROUP PLC	0.01%	976	37.62K	0	0
Sep 30, 2025	PANAGORA ASSET MANAGEMENT INC	0.14%	17.09K	658.8K	-1.29K	-6.99%
Sep 30, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.21%	24.98K	962.73K	-1.22K	-4.66%
Sep 30, 2025	JANE STREET GROUP, LLC	0.23%	27.36K	1.05M	27.36K	+100.00%
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.24%	28.9K	1.11M	17K	+142.86%
Sep 30, 2025	RBF CAPITAL, LLC	0.26%	30.62K	1.18M	0	0
Sep 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.27%	32.62K	1.26M	32.62K	+100.00%
Sep 30, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0%	408	15.72K	-1.87K	-82.05%
Sep 30, 2025	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0%	583	22.47K	1	+0.17%
Sep 30, 2025	COSTELLO ASSET MANAGEMENT, INC	0.01%	600	23.12K	0	0
Sep 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0.01%	778	29.98K	756	+3,436.36%
Sep 30, 2025	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0.02%	2.86K	110.07K	1.24K	+76.95%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.03%	3.23K	124.33K	2.35K	+266.59%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0.05%	6.48K	249.6K	1.09K	+20.23%
Sep 30, 2025	STATE OF WISCONSIN INVESTMENT BOARD	0.11%	13.57K	523.03K	13.57K	+100.00%
Sep 30, 2025	LOS ANGELES CAPITAL MANAGEMENT LLC	0.12%	14.68K	565.61K	0	0
Sep 30, 2025	DIMENSIONAL FUND ADVISORS LP	0.24%	29.19K	1.12M	1.27K	+4.55%
Sep 30, 2025	CM MANAGEMENT, LLC	0.4%	48K	1.85M	-16K	-25.00%
Sep 30, 2025	BLACKROCK, INC.	4.94%	592.9K	22.85M	1.23K	+0.21%
Sep 30, 2025	VANGUARD GROUP INC	5.56%	668.11K	25.75M	29.3K	+4.59%
Sep 30, 2025	FMR LLC	8.95%	1.07M	41.4M	-5.26K	-0.49%
Sep 30, 2025	MORGAN STANLEY	13.72%	1.65M	63.48M	102.03K	+6.60%
Sep 30, 2025	BVF INC/IL	21.57%	2.59M	99.83M	0	0
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.51%	61.35K	2.36M	1.56K	+2.61%
Sep 30, 2025	STONEPINE CAPITAL MANAGEMENT, LLC	0.96%	115.46K	4.45M	-36.68K	-24.11%
Sep 30, 2025	TRUVESTMENTS CAPITAL LLC	0%	290	11.18K	0	0
Sep 30, 2025	CITIGROUP INC	0%	316	12.18K	-3.4K	-91.49%
Sep 30, 2025	NATIXIS	0%	372	14.34K	-1.09K	-74.56%
Sep 30, 2025	CITADEL ADVISORS LLC	0.06%	7.58K	292.17K	7.58K	+100.00%
Sep 30, 2025	ROYAL BANK OF CANADA	0.01%	1.53K	59K	-3.1K	-67.00%
Sep 30, 2025	MACQUARIE GROUP LTD	0.06%	6.93K	221K	3.47K	+100.00%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	0.07%	8.07K	311.17K	8.07K	+100.00%
Sep 30, 2025	DEUTSCHE BANK AG\	0.07%	8.48K	326.67K	0	0
Sep 30, 2025	AMERITAS INVESTMENT PARTNERS, INC.	0.01%	959	36.96K	0	0
Sep 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.02%	2.36K	91.03K	0	0
Sep 30, 2025	ADVISOR GROUP HOLDINGS, INC.	0.03%	3.55K	116.6K	75	+2.16%
Sep 30, 2025	JPMORGAN CHASE & CO	0.03%	3.8K	146.3K	-644	-14.50%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.03%	3.96K	152.43K	-245	-5.83%
Sep 30, 2025	UBS GROUP AG	0.03%	4.15K	159.98K	-11.96K	-74.23%
Sep 30, 2025	MIRAE ASSET GLOBAL ETFS HOLDINGS LTD.	0.04%	4.31K	166.18K	-828	-16.11%
Sep 30, 2025	COVESTOR LTD	0%	0	-	-58	-100.00%
Jun 30, 2025	DIMENSIONAL FUND ADVISORS LP	0.23%	27.92K	705.79K	6.04K	+27.60%
Jun 30, 2025	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0%	582	14.67M	0	0
Jun 30, 2025	TD WATERHOUSE CANADA INC.	0%	1	26	0	0
Jun 30, 2025	MARSHALL WACE, LLP	0.14%	16.31K	410.96K	1.78K	+12.21%
Jun 30, 2025	TRUVESTMENTS CAPITAL LLC	0%	290	7.31K	0	0
Jun 30, 2025	GAMMA INVESTING LLC	0%	102	2.57K	15	+17.24%
Jun 30, 2025	STERLING CAPITAL MANAGEMENT LLC	0%	94	2.37K	35	+59.32%
Jun 30, 2025	ACUITAS INVESTMENTS, LLC	0%	0	-	-5.67K	-100.00%
Jun 30, 2025	SQUAREPOINT OPS LLC	0%	0	-	-10.31K	-100.00%
Jun 30, 2025	EVERSEPT PARTNERS, LP	0%	0	-	-45.02K	-100.00%
Jun 30, 2025	COREBRIDGE FINANCIAL, INC.	0%	0	-	-3.98K	-100.00%
Jun 30, 2025	BVF INC/IL	21.57%	2.59M	65.28M	-392.72K	-13.17%
Jun 30, 2025	BLACKROCK, INC.	4.93%	591.67K	14.91M	58.89K	+11.05%
Jun 30, 2025	MORGAN STANLEY	12.87%	1.54M	38.93M	422.68K	+37.66%
Jun 30, 2025	FMR LLC	8.99%	1.08M	27.21M	-8.78K	-0.81%
Jun 30, 2025	TLS ADVISORS LLC	0.99%	119.04K	3M	0	0
Jun 30, 2025	HIGHVISTA STRATEGIES LLC	0.95%	114.55K	2.89M	0	0
Jun 30, 2025	RBF CAPITAL, LLC	0.26%	30.62K	771.52K	0	0
Jun 30, 2025	EVERSOURCE WEALTH ADVISORS, LLC	0%	79	1.99K	79	+100.00%
Jun 30, 2025	COVESTOR LTD	0%	58	1K	58	+100.00%
Jun 30, 2025	ROTHSCHILD INVESTMENT LLC	0%	3	76	0	0
Jun 30, 2025	TRUE WEALTH DESIGN, LLC	0%	3	76	0	0
Jun 30, 2025	OPALEYE MANAGEMENT INC.	2.12%	255.09K	6.43M	2.04K	+0.81%
Jun 30, 2025	WOODLINE PARTNERS LP	1.5%	180.23K	4.54M	11.68K	+6.93%
Jun 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.02%	2.36K	59.52K	0	0
Jun 30, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0.02%	2.27K	57.28K	1.52K	+203.07%
Jun 30, 2025		0.01%	1.61K	40.67K	0	0
Jun 30, 2025	NATIXIS	0.01%	1.46K	36.84K	-62	-4.07%
Jun 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.01%	880	22.18K	418	+90.48%
Jun 30, 2025	COSTELLO ASSET MANAGEMENT, INC	0.01%	600	15.12K	0	0
Jun 30, 2025	STONEPINE CAPITAL MANAGEMENT, LLC	1.27%	152.14K	3.83M	22.33K	+17.20%
Jun 30, 2025	CM MANAGEMENT, LLC	0.53%	64K	1.61M	0	0
Jun 30, 2025	LOS ANGELES CAPITAL MANAGEMENT LLC	0.12%	14.68K	369.84K	14.68K	+100.00%
Jun 30, 2025	MIRAE ASSET GLOBAL ETFS HOLDINGS LTD.	0.04%	5.14K	129.53K	270	+5.54%
Jun 30, 2025	LAZARD ASSET MANAGEMENT LLC	0.04%	4.82K	121K	4.82K	+100.00%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0.04%	4.2K	105.84K	-757	-15.27%
Jun 30, 2025	CITIGROUP INC	0.03%	3.71K	93.57K	-2.02K	-35.21%
Jun 30, 2025	MACQUARIE GROUP LTD	0.03%	3.47K	87K	0	0
Jun 30, 2025	ADVISOR GROUP HOLDINGS, INC.	0.03%	3.48K	87.67K	26	+0.75%
Jun 30, 2025	LEGAL & GENERAL GROUP PLC	0.01%	976	24.64K	124	+14.55%
Jun 30, 2025	AMERITAS INVESTMENT PARTNERS, INC.	0.01%	959	24.17K	355	+58.77%
Jun 30, 2025	GROUP ONE TRADING, L.P.	0.01%	900	22.68K	0	0
Jun 30, 2025	JPMORGAN CHASE & CO	0.04%	4.44K	111.89K	543	+13.93%
Jun 30, 2025	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0.01%	1.61K	40.67K	0	0
Jun 30, 2025	VANGUARD GROUP INC	5.32%	638.81K	16.1M	179.73K	+39.15%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.7%	203.6K	5.13M	16.93K	+9.07%
Jun 30, 2025	STATE STREET CORP	1.28%	153.48K	3.87M	8.76K	+6.05%
Jun 30, 2025	NORTHERN TRUST CORP	0.78%	94.22K	2.37M	5.17K	+5.81%
Jun 30, 2025	BANK OF NEW YORK MELLON CORP	0.5%	59.79K	1.51M	1.88K	+3.24%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.22%	26.38K	664.65K	3.22K	+13.89%
Jun 30, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.22%	26.2K	660.24K	0	0
Jun 30, 2025	OCCUDO QUANTITATIVE STRATEGIES LP	0.17%	20.93K	1.3K	20.93K	+100.00%
Jun 30, 2025	PANAGORA ASSET MANAGEMENT INC	0.15%	18.38K	463.15K	18.38K	+100.00%
Jun 30, 2025	BARCLAYS PLC	0.14%	16.64K	420K	7.74K	+87.05%
Jun 30, 2025	UBS GROUP AG	0.13%	16.11K	405.97K	11.28K	+233.33%
Jun 30, 2025	RHUMBLINE ADVISERS	0.11%	13.25K	333.87K	2.02K	+17.98%
Jun 30, 2025	DEUTSCHE BANK AG\	0.07%	8.48K	213.6K	2.04K	+31.76%
Jun 30, 2025	NUVEEN, LLC	0.11%	12.71K	320.19K	-1.66K	-11.54%
Jun 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.1%	11.9K	299.88K	-1.8K	-13.14%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.1%	11.56K	291.29K	1.31K	+12.73%
Jun 30, 2025	WELLS FARGO & COMPANY/MN	0.04%	5.39K	135.74K	841	+18.50%
Jun 30, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.04%	5.3K	133.56K	929	+21.25%
Jun 30, 2025	ROYAL BANK OF CANADA	0.04%	4.63K	117K	-1.12K	-19.48%
Jun 30, 2025	RAYMOND JAMES FINANCIAL INC	0.04%	4.6K	115.92K	4.6K	+100.00%
Mar 31, 2025	RBF CAPITAL, LLC	0.26%	30.62K	610.18K	0	0
Mar 31, 2025	EVERSEPT PARTNERS, LP	0.38%	45.02K	897.19K	-50.4K	-52.82%
Mar 31, 2025	STATE STREET CORP	1.21%	144.73K	2.88M	200	+0.14%
Mar 31, 2025	WOODLINE PARTNERS LP	1.41%	168.55K	3.36M	12.28K	+7.86%
Mar 31, 2025	OPALEYE MANAGEMENT INC.	2.11%	253.04K	5.04M	3.04K	+1.22%
Mar 31, 2025	FMR LLC	9.09%	1.09M	21.69M	-1.68K	-0.15%
Mar 31, 2025	MORGAN STANLEY	9.38%	1.12M	22.37M	804.97K	+253.68%
Mar 31, 2025	BVF INC/IL	24.92%	2.98M	59.45M	-650.72K	-17.91%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.1%	11.52K	229.65K	-9.45K	-45.05%
Mar 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0.11%	13.7K	273.04K	-2.4K	-14.91%
Mar 31, 2025	JPMORGAN CHASE & CO	0.03%	3.9K	77.67K	-8.19K	-67.76%
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	0.12%	14.05K	280.1K	14.05K	+100.00%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.19%	23.16K	461.54K	45	+0.19%
Mar 31, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.22%	26.2K	522.17K	700	+2.75%
Mar 31, 2025	BANK OF NEW YORK MELLON CORP	0.48%	57.91K	1.15M	366	+0.64%
Mar 31, 2025	LEGAL & GENERAL GROUP PLC	0.01%	852	16.98K	0	0
Mar 31, 2025		0.01%	1.61K	32.17K	0	0
Mar 31, 2025	ADVISOR GROUP HOLDINGS, INC.	0.03%	3.45K	68.81K	100	+2.98%
Mar 31, 2025	MACQUARIE GROUP LTD	0.03%	3.47K	69M	0	0
Mar 31, 2025	COREBRIDGE FINANCIAL, INC.	0.03%	3.98K	79.4K	-8	-0.20%
Mar 31, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.04%	4.37K	87.11K	0	0
Mar 31, 2025	WELLS FARGO & COMPANY/MN	0.04%	4.55K	90.6K	246	+5.72%
Mar 31, 2025	UBS GROUP AG	0.04%	4.83K	96.32K	-1.9K	-28.19%
Mar 31, 2025	SQUAREPOINT OPS LLC	0.09%	10.31K	205.42K	823	+8.68%
Mar 31, 2025	MARSHALL WACE, LLP	0.12%	14.53K	289.64K	14.53K	+100.00%
Mar 31, 2025	DIMENSIONAL FUND ADVISORS LP	0.18%	21.88K	436.11K	-532	-2.37%
Mar 31, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.02%	2.36K	47K	0	0
Mar 31, 2025	TLS ADVISORS LLC	0.99%	119.04K	2.37M	0	0
Mar 31, 2025	HIGHVISTA STRATEGIES LLC	0.96%	114.55K	2.28M	0	0
Mar 31, 2025	NORTHERN TRUST CORP	0.74%	89.05K	1.77M	-2.13K	-2.33%
Mar 31, 2025	CM MANAGEMENT, LLC	0.53%	64K	1.28M	9K	+16.36%
Mar 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.09%	10.25K	204.36K	10.25K	+100.00%
Mar 31, 2025	CITADEL ADVISORS LLC	0.08%	9.64K	192.09K	-1.91K	-16.55%
Mar 31, 2025	BARCLAYS PLC	0.07%	8.9K	177K	-3.89K	-30.41%
Mar 31, 2025	DEUTSCHE BANK AG\	0.05%	6.43K	128.21K	6.31K	+5,087.90%
Mar 31, 2025	ROYAL BANK OF CANADA	0.05%	5.75K	114K	-289	-4.79%
Mar 31, 2025	CITIGROUP INC	0.05%	5.73K	114.22K	-611	-9.63%
Mar 31, 2025	ACUITAS INVESTMENTS, LLC	0.05%	5.67K	113.08K	-55.03K	-90.65%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0.04%	4.96K	98.79K	-2.84K	-36.42%
Mar 31, 2025	MIRAE ASSET GLOBAL ETFS HOLDINGS LTD.	0.04%	4.87K	97.06K	234	+5.05%
Mar 31, 2025	NATIXIS	0.01%	1.52K	30.16K	-202	-11.70%
Mar 31, 2025	GROUP ONE TRADING, L.P.	0.01%	900	17.94K	500	+125.00%
Mar 31, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0.01%	750	14.95K	296	+65.20%
Mar 31, 2025	AMERITAS INVESTMENT PARTNERS, INC.	0.01%	604	12.04K	0	0
Mar 31, 2025	STONEPINE CAPITAL MANAGEMENT, LLC	1.08%	129.81K	2.59M	4.11K	+3.27%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.56%	186.67K	3.72M	4.48K	+2.46%
Mar 31, 2025	VANGUARD GROUP INC	3.84%	459.09K	9.15M	-4.75K	-1.02%
Mar 31, 2025	BLACKROCK, INC.	4.45%	532.79K	10.62M	-6.14K	-1.14%
Mar 31, 2025	RHUMBLINE ADVISERS	0.09%	11.23K	223.81K	165	+1.49%
Mar 31, 2024	TLS ADVISORS LLC	1.05%	120.37K	2.9M	-100	-0.08%
Mar 31, 2024	NELSON, VAN DENBURG & CAMPBELL WEALTH MANAGEMENT GROUP, LLC	0%	501	12.05K	0	0
Mar 31, 2024	LEGAL & GENERAL GROUP PLC	0%	531	12.77K	-176	-24.89%
Mar 31, 2024	CWM, LLC	0.01%	587	14K	2	+0.34%
Mar 31, 2024	GLOBAL RETIREMENT PARTNERS, LLC	0.01%	600	14.43K	0	0
Mar 31, 2024	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0.01%	735	17.68K	-468	-38.90%
Mar 31, 2024	ROYAL BANK OF CANADA	0.01%	1.12K	27K	-3.38K	-75.04%
Mar 31, 2024	CITIGROUP INC	0.01%	1.37K	32.97K	327	+31.32%
Mar 31, 2024	CITADEL ADVISORS LLC	0.01%	1.7K	40.89K	-700	-29.17%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.03%	3.92K	94.35K	-6.69K	-63.03%
Mar 31, 2024	METLIFE INVESTMENT MANAGEMENT, LLC	0.03%	3.96K	95.24K	3.96K	+100.00%
Mar 31, 2024	DEUTSCHE BANK AG\	0.04%	4.64K	111.5K	-172	-3.58%
Mar 31, 2024	FIRST MANHATTAN CO. LLC.	0.04%	5K	120.25K	0	0
Mar 31, 2024	BARCLAYS PLC	0.05%	5.16K	124K	-4.93K	-48.84%
Mar 31, 2024	KNOTT DAVID M JR	0.17%	19.72K	474K	0	0
Mar 31, 2024	DIMENSIONAL FUND ADVISORS LP	0.22%	25.52K	613.66K	0	0
Mar 31, 2024	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.23%	26.4K	634.92K	-200	-0.75%
Mar 31, 2024	RBF CAPITAL, LLC	0.27%	30.62K	736.32K	-2.39K	-7.24%
Mar 31, 2024	CM MANAGEMENT, LLC	0.48%	55K	1.32M	0	0
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.53%	60.69K	1.46M	-1.9K	-3.04%
Mar 31, 2024	WOODLINE PARTNERS LP	0.63%	72.11K	1.73M	21.55K	+42.62%
Mar 31, 2024	NEW YORK STATE COMMON RETIREMENT FUND	0.05%	5.64K	136K	376	+7.15%
Mar 31, 2024	UBS GROUP AG	0.06%	7.36K	176.89K	-590	-7.43%
Mar 31, 2024	NORTHERN TRUST CORP	0.75%	86.1K	2.07M	-872	-1.00%
Mar 31, 2024	EVERSEPT PARTNERS, LP	0.85%	97.07K	2.33M	3.34K	+3.56%
Mar 31, 2024	HIGHVISTA STRATEGIES LLC	1.04%	118.9K	2.86M	0	0
Mar 31, 2024	ACUITAS INVESTMENTS, LLC	1.07%	123.2K	2.96M	-13.94K	-10.16%
Mar 31, 2024	STATE STREET CORP	1.21%	138.95K	3.34M	14.53K	+11.67%
Mar 31, 2024	MORGAN STANLEY	1.39%	159.18K	3.83M	143.64K	+923.88%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	1.48%	170.05K	4.09M	9.11K	+5.66%
Mar 31, 2024	OPALEYE MANAGEMENT INC.	2.18%	250K	6.01M	0	0
Mar 31, 2024	STONEPINE CAPITAL MANAGEMENT, LLC	2.21%	253.77K	6.1M	3.77K	+1.51%
Mar 31, 2024	VANGUARD GROUP INC	3.53%	405.53K	9.75M	-15.94K	-3.78%
Mar 31, 2024	RHUMBLINE ADVISERS	0.07%	8.36K	201.07K	204	+2.50%
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	0.08%	8.78K	212K	8.78K	+100.00%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.09%	9.99K	240.21K	9.99K	+100.00%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.13%	15.4K	370.37K	15.4K	+100.00%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.17%	19.56K	470.42K	0	0
Mar 31, 2024	BLACKROCK INC.	4.19%	480.51K	11.56M	-7.98K	-1.63%
Mar 31, 2024	FMR LLC	10.11%	1.16M	27.91M	5.57K	+0.48%
Mar 31, 2024	BVF INC/IL	31.66%	3.63M	87.39M	0	0
Mar 31, 2024	AMERITAS INVESTMENT PARTNERS, INC.	0.01%	604	14.53K	0	0
Mar 31, 2024	NATIXIS	0.02%	1.73K	41.51K	0	0
Mar 31, 2024	WELLS FARGO & COMPANY/MN	0.02%	2.78K	66.8K	333	+13.62%
Mar 31, 2024	JPMORGAN CHASE & CO	0.03%	3.23K	77.75K	-1.76K	-35.24%
Mar 31, 2024	MACQUARIE GROUP LTD	0.03%	3.47K	83K	0	0
Mar 31, 2024	BNP PARIBAS ARBITRAGE, SNC	0.03%	3.54K	85.21K	1.27K	+55.60%
Mar 31, 2024	AMERICAN INTERNATIONAL GROUP, INC.	0.03%	3.6K	86.65K	-31	-0.85%
Mar 31, 2024	METROPOLITAN LIFE INSURANCE CO/NY	0%	411	9.89K	411	+100.00%
Mar 31, 2024	TD WATERHOUSE CANADA INC.	0%	0	-	-1	-100.00%
Mar 31, 2024	AJOVISTA, LLC	0%	0	-	-1.16K	-100.00%
Mar 31, 2024	SCARBOROUGH ADVISORS, LLC	0%	0	-	-175	-100.00%
Mar 31, 2024	RENAISSANCE TECHNOLOGIES LLC	0%	0	-	-12.3K	-100.00%
Mar 31, 2024	PNC FINANCIAL SERVICES GROUP, INC.	0%	2	48	0	0
Mar 31, 2024	NISA INVESTMENT ADVISORS, LLC	0%	8	192	0	0
Mar 31, 2024	ALLSPRING GLOBAL INVESTMENTS HOLDINGS, LLC	0%	15	360	0	0
Mar 31, 2024	ADVISOR GROUP HOLDINGS, INC.	0%	71	1.71K	1	+1.43%
Mar 31, 2024	GAMMA INVESTING LLC	0%	75	1.8K	67	+837.50%
Mar 31, 2024	AMALGAMATED BANK	0%	247	6K	-391	-61.29%
Mar 31, 2024	TRUVESTMENTS CAPITAL LLC	0%	400	9.62K	0	0
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.17%	19.56K	361.86K	0	0
Dec 31, 2023	KNOTT DAVID M JR	0.17%	19.72K	365K	0	0
Dec 31, 2023	DIMENSIONAL FUND ADVISORS LP	0.22%	25.52K	472.05K	-2.86K	-10.08%
Dec 31, 2023	CITADEL ADVISORS LLC	0.02%	2.4K	44.4K	-2.3K	-48.94%
Dec 31, 2023	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.23%	26.6K	492.1K	0	0
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	0.25%	28.3K	523.57K	274	+0.98%
Dec 31, 2023	RBF CAPITAL, LLC	0.29%	33.01K	610.59K	-1.78K	-5.12%
Dec 31, 2023	WOODLINE PARTNERS LP	0.44%	50.56K	935.34K	50.56K	+100.00%
Dec 31, 2023	CM MANAGEMENT, LLC	0.48%	55K	1.02M	55K	+100.00%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.55%	62.59K	1.16M	-70	-0.11%
Dec 31, 2023	NORTHERN TRUST CORP	0.76%	86.97K	1.61M	-240	-0.28%
Dec 31, 2023	EVERSEPT PARTNERS, LP	0.82%	93.73K	1.73M	3.78K	+4.20%
Dec 31, 2023		0.01%	1.16K	21.5K	1.16K	+100.00%
Dec 31, 2023	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	0.01%	1.2K	22.26K	-410	-25.42%
Dec 31, 2023	RHUMBLINE ADVISERS	0.07%	8.16K	150.9K	-205	-2.45%
Dec 31, 2023	HIGHVISTA STRATEGIES LLC	1.04%	118.9K	2.2M	0	0
Dec 31, 2023	TLS ADVISORS LLC	1.05%	120.47K	2.23M	-200	-0.17%
Dec 31, 2023	STATE STREET CORP	1.08%	124.42K	2.3M	1.99K	+1.63%
Dec 31, 2023	ACUITAS INVESTMENTS, LLC	1.2%	137.13K	2.54M	0	0
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.4%	160.94K	2.98M	4.21K	+2.68%
Dec 31, 2023	OPALEYE MANAGEMENT INC.	2.18%	250K	4.63M	-24.5K	-8.93%
Dec 31, 2023	STONEPINE CAPITAL MANAGEMENT, LLC	2.18%	250K	4.63M	-186.6K	-42.74%
Dec 31, 2023	UBS GROUP AG	0.07%	7.95K	146.98K	3.97K	+99.87%
Dec 31, 2023	VANGUARD GROUP INC	3.67%	421.47K	7.8M	6.84K	+1.65%
Dec 31, 2023	BLACKROCK INC.	4.26%	488.49K	9.04M	31K	+6.78%
Dec 31, 2023	FMR LLC	10.07%	1.16M	21.37M	-29.01K	-2.45%
Dec 31, 2023	BVF INC/IL	31.67%	3.63M	67.22M	0	0
Dec 31, 2023	NATIXIS	0.02%	1.73K	31.93K	0	0
Dec 31, 2023	BNP PARIBAS ARBITRAGE, SNC	0.02%	2.28K	42.12K	1.23K	+118.31%
Dec 31, 2023	WELLS FARGO & COMPANY/MN	0.02%	2.45K	45.22K	445	+22.25%
Dec 31, 2023	MACQUARIE GROUP LTD	0.03%	3.47K	64K	0	0
Dec 31, 2023	AMERICAN INTERNATIONAL GROUP, INC.	0.03%	3.63K	67.23K	-15	-0.41%
Dec 31, 2023	ROYAL BANK OF CANADA	0.04%	4.5K	83K	2.31K	+105.62%
Dec 31, 2023	DEUTSCHE BANK AG\	0.04%	4.81K	88.95K	4.81K	+100.00%
Dec 31, 2023	JPMORGAN CHASE & CO	0.04%	4.99K	92.35K	-134	-2.61%
Dec 31, 2023	FIRST MANHATTAN CO. LLC.	0.04%	5K	92.5K	-2.5K	-33.33%
Dec 31, 2023	NEW YORK STATE COMMON RETIREMENT FUND	0.05%	5.26K	97K	-15	-0.28%
Dec 31, 2023	GLOBAL RETIREMENT PARTNERS, LLC	0.01%	600	11.85K	0	0
Dec 31, 2023	AMERITAS INVESTMENT PARTNERS, INC.	0.01%	604	11.17K	0	0
Dec 31, 2023	AMALGAMATED BANK	0.01%	638	12K	-73	-10.27%
Dec 31, 2023	TOWER RESEARCH CAPITAL LLC (TRC)	0.01%	651	12.04K	-131	-16.75%
Dec 31, 2023	LEGAL & GENERAL GROUP PLC	0.01%	707	13.08K	0	0
Dec 31, 2023	CITIGROUP INC	0.01%	1.04K	19.31K	1.04K	+26,000.00%
Dec 31, 2023	BARCLAYS PLC	0.09%	10.09K	187K	8.72K	+638.51%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.09%	10.61K	196.29K	4.38K	+70.36%
Dec 31, 2023	SQUAREPOINT OPS LLC	0.11%	12.27K	227.07K	12.27K	+100.00%
Dec 31, 2023	RENAISSANCE TECHNOLOGIES LLC	0.11%	12.3K	227K	-5.91K	-32.46%
Dec 31, 2023	MORGAN STANLEY	0.14%	15.55K	287.62K	9.55K	+159.03%

Insiders

Insiders	Designation	Shares Held
BVF PARTNERS L P/IL	10 percent owner	1.27M
PERRY MATTHEW D	director	200K
HUGHES OWEN	Chief Executive Officer	102K
BURNS THOMAS M.	SVP, Finance & CFO	30.08K
NEAL JAMES R	CEO	11.82K
LIMBER JOSEPH M	director	10K
SITKO BRADLEY	Chief Investment Officer	7.05K

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Dec 04, 2025	HUGHES OWEN	PURCHASE	25.05	100K	2.51M	102K
Sep 22, 2025	BURNS THOMAS M.	SALE	36.81	15	552.15	30.08K
Jun 30, 2025	SITKO BRADLEY	PURCHASE	25.39	2K	50.78K	7.05K
May 20, 2025	HUGHES OWEN	SALE	25.38	25.64K	650.67K	62.7K
May 20, 2025	BURNS THOMAS M.	SALE	25.38	10.48K	266.03K	22.56K
May 16, 2025	BVF PARTNERS L P/IL	SALE	27.10	265.32K	7.19M	1.27M
Apr 07, 2025	SITKO BRADLEY	PURCHASE	24.70	2K	49.4K	5.05K
Apr 07, 2025	LIMBER JOSEPH M	PURCHASE	25.60	5.24K	134.22K	10K
Apr 04, 2025	LIMBER JOSEPH M	PURCHASE	25.56	3.35K	85.52K	4.76K
Apr 03, 2025	LIMBER JOSEPH M	PURCHASE	25.44	1.41K	35.9K	1.41K
Apr 01, 2025	BURNS THOMAS M.	PURCHASE	25.46	1K	25.46K	2K
Mar 31, 2025	SITKO BRADLEY	PURCHASE	25.39	245	6.22K	3.05K
Mar 21, 2025	SITKO BRADLEY	PURCHASE	25.43	2.8K	71.2K	2.8K
Jan 24, 2025	BVF PARTNERS L P/IL	SALE	26.10	149.98K	3.91M	0
Jan 08, 2025	SITKO BRADLEY	PURCHASE	25.60	75	1.92K	75
Dec 31, 2024	SITKO BRADLEY	PURCHASE	25.90	300	7.77K	9.15K
Nov 13, 2024	BURNS THOMAS M.	SALE	29.94	9.78K	292.66K	14.55K
Nov 13, 2024	HUGHES OWEN	SALE	29.95	21.88K	655.34K	34.98K
Oct 03, 2023	SITKO BRADLEY	PURCHASE	13.89	250	3.47K	5.6K
Oct 02, 2023	HUGHES OWEN	PURCHASE	13.83	1K	13.83K	3.5K
Oct 02, 2023	SITKO BRADLEY	PURCHASE	14.25	1.5K	21.38K	5.35K
Sep 26, 2023	HUGHES OWEN	PURCHASE	14.43	2.5K	36.06K	2.5K
Sep 25, 2023	HUGHES OWEN	PURCHASE	14.65	1	14.65	1
May 31, 2023	SITKO BRADLEY	PURCHASE	17.00	500	8.5K	2.5K
May 24, 2023	HUGHES OWEN	PURCHASE	23.79	1.03K	24.55K	2K
May 23, 2023	SITKO BRADLEY	PURCHASE	19.00	850	16.15K	3.85K
May 23, 2023	HUGHES OWEN	PURCHASE	23.33	200	4.67K	200
May 19, 2023	SITKO BRADLEY	PURCHASE	19.50	1K	19.5K	3K
May 16, 2023	SITKO BRADLEY	PURCHASE	23.19	300	6.96K	1.8K
May 15, 2023	SITKO BRADLEY	PURCHASE	23.40	1.5K	35.1K	1.5K
May 12, 2023	SITKO BRADLEY	PURCHASE	18.66	43	802.38	43
Jan 06, 2023	BVF PARTNERS L P/IL	PURCHASE	21.98	1.57K	34.58K	1.62M
Jan 05, 2023	BVF PARTNERS L P/IL	PURCHASE	18.39	15.67K	288.1K	1.62M
Sep 27, 2022	BVF PARTNERS L P/IL	PURCHASE	16.89	678	11.45K	1.6M
Sep 26, 2022	BVF PARTNERS L P/IL	PURCHASE	16.83	3.02K	50.85K	1.6M
Sep 23, 2022	BVF PARTNERS L P/IL	PURCHASE	16.50	9.89K	163.07K	1.6M
Sep 16, 2022	BVF PARTNERS L P/IL	PURCHASE	17.89	10.9K	194.92K	1.59M
Sep 15, 2022	BVF PARTNERS L P/IL	PURCHASE	17.96	5.58K	100.14K	1.58M
Sep 14, 2022	BVF PARTNERS L P/IL	PURCHASE	17.25	26.44K	456.04K	1.57M
Jul 15, 2022	NEAL JAMES R	SALE	31.86	905	28.83K	11.82K
Jul 15, 2022	BURNS THOMAS M.	SALE	31.66	2K	63.32K	6.56K
Mar 23, 2022	NEAL JAMES R	SALE	30.02	1.11K	33.35K	11.82K
Mar 21, 2022	BURNS THOMAS M.	SALE	30.02	2.34K	70.21K	6.56K
Mar 21, 2022	NEAL JAMES R	SALE	29.00	50K	1.45M	11.82K
Jun 25, 2021	NEAL JAMES R	SALE	35.13	686	24.1K	11.82K
Mar 31, 2021	BVF PARTNERS L P/IL	SALE	38.36	84.25K	3.23M	75.29K
Dec 15, 2020	BURNS THOMAS M.	SALE	42.04	5.61K	235.74K	6.56K
Dec 15, 2020	NEAL JAMES R	SALE	42.04	5.71K	239.9K	20.85K
Dec 11, 2020	BVF PARTNERS L P/IL	PURCHASE	25.00	200K	5M	200K
Dec 11, 2020	PERRY MATTHEW D	PURCHASE	25.00	200K	5M	200K
Nov 23, 2020	NEAL JAMES R	SALE	32.96	13.13K	432.66K	20.85K
Nov 23, 2020	BURNS THOMAS M.	SALE	32.93	5.13K	168.75K	6.56K
Nov 20, 2020	NEAL JAMES R	SALE	33.35	426	14.21K	20.85K
Nov 20, 2020	BURNS THOMAS M.	SALE	33.35	426	14.21K	6.56K
Nov 05, 2020	NEAL JAMES R	SALE	27.50	727	19.99K	20.85K
Nov 05, 2020	BURNS THOMAS M.	SALE	27.50	726	19.97K	6.56K
Sep 23, 2020	BVF PARTNERS L P/IL	PURCHASE	18.20	7.2K	131.06K	1.75M
Sep 22, 2020	BVF PARTNERS L P/IL	PURCHASE	18.45	4.99K	92.06K	1.74M
Sep 21, 2020	BVF PARTNERS L P/IL	PURCHASE	18.39	10.07K	185.12K	1.74M
Sep 04, 2020	BVF PARTNERS L P/IL	PURCHASE	18.77	3.83K	71.89K	1.73M
Sep 01, 2020	BVF PARTNERS L P/IL	PURCHASE	18.87	7.67K	144.74K	1.72M
Aug 31, 2020	BVF PARTNERS L P/IL	PURCHASE	18.48	6.86K	126.81K	1.72M
Aug 28, 2020	BVF PARTNERS L P/IL	PURCHASE	19.17	922	17.68K	1.71M
Aug 25, 2020	BVF PARTNERS L P/IL	PURCHASE	19.75	2.24K	44.31K	1.71M
Aug 24, 2020	BVF PARTNERS L P/IL	PURCHASE	19.31	5.18K	100K	1.71M
Aug 21, 2020	BVF PARTNERS L P/IL	PURCHASE	19.32	1.61K	31.05K	1.7M
Aug 20, 2020	BVF PARTNERS L P/IL	PURCHASE	19.12	1.77K	33.88K	1.97M
Aug 19, 2020	BVF PARTNERS L P/IL	PURCHASE	19.70	3.5K	68.88K	1.97M
Aug 18, 2020	BVF PARTNERS L P/IL	PURCHASE	19.27	895	17.25K	1.96M
Aug 14, 2020	BVF PARTNERS L P/IL	PURCHASE	18.69	21.92K	409.81K	1.96M
Aug 13, 2020	BVF PARTNERS L P/IL	PURCHASE	17.80	1.05K	18.69K	1.94M
Aug 12, 2020	BVF PARTNERS L P/IL	PURCHASE	17.34	4.05K	70.23K	1.94M
Mar 25, 2020	BVF PARTNERS L P/IL	PURCHASE	17.20	8.26K	142.13K	1.28M
Mar 23, 2020	NEAL JAMES R	PURCHASE	14.50	1K	14.5K	20.85K
Mar 20, 2020	NEAL JAMES R	PURCHASE	16.41	1K	16.41K	19.85K
Mar 18, 2020	BVF PARTNERS L P/IL	PURCHASE	14.52	4.44K	64.47K	1.27M
Mar 17, 2020	BVF PARTNERS L P/IL	PURCHASE	15.73	8.11K	127.65K	1.27M
Mar 16, 2020	BVF PARTNERS L P/IL	PURCHASE	15.73	10.16K	159.92K	1.26M
Mar 13, 2020	BVF PARTNERS L P/IL	PURCHASE	18.34	100K	1.83M	1.25M
Dec 18, 2019	BVF PARTNERS L P/IL	PURCHASE	22.00	165.96K	3.65M	1.1M
Nov 06, 2019	NEAL JAMES R	SALE	22.00	4.35K	95.66K	17.67K
Sep 19, 2019	NEAL JAMES R	SALE	20.69	3.73K	77.13K	20.31K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE100K1

SALES00

NET SHARES100K1

SHARES HELD102K1

% NET SHARES-1.96%0%

XOMA Stock Ownership Breakdown

XOMA Royalty

Stock Outstanding Shares

Market Insider

Institutional Ownership

Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions

Stock Outstanding Shares

Market Insider

Institutional Ownership

Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions