How many institutions own SWTX stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own SWTX shares is 413, representing 87.4% of the company's common stock.

Who are the major shareholders selling SpringWorks Therapeutics, Inc. stock?

CHARLES SCHWAB INVESTMENT MANAGEMENT INC, in the last quarter, reduced its stake in SWTX by -29.64% restricting it's holding to 432.62 thousand shares of worth nearly $20.33M. ARROWMARK COLORADO HOLDINGS LLC also lessened -57.71% of the SWTX shares from its portfolio, reducing its holding to 617.02 thousand shares of worth $28.99M. SUSQUEHANNA INTERNATIONAL GROUP, LLP also shunned SWTX shares holding by -22.25% last quarter which brought its holding to 484.87 thousand shares worth $22.78M.

Investors who are buying SWTX stock?

As per its latest 13F filing, SOROS FUND MANAGEMENT LLC increased its stake in SWTX by 9.88% in the last quarter. The institutional holder raised its holding to 501.99 thousand shares having worth more than $23.59M. MILLENNIUM MANAGEMENT LLC also added 8.13% more shares of SWTX to its portfolio, raising its holding to 544.86 thousand shares of worth $25.60M. HUDSON BAY CAPITAL MANAGEMENT LP also increased its SWTX shares holding by 2.51% which brought its holding to 547.01 thousand shares worth $25.70M.

SWTX's major insiders: who are they?

The insider with the most stakes in SWTX is OrbiMed Capital GP VI LLC , at the company. Additionally, SWTX stock is highly held by 10 percent owner ORBIMED ADVISORS LLC and 10 percent owner Bain Capital Life Sciences Investors, LLC among others.

Did an insider recently sell SWTX stock?

Company executives, directors, and other insiders own 1.28% percent of SpringWorks Therapeutics, Inc.'s stock. Within the last six months, there have been 0 transaction(s) in which SWTX insiders have sold stock, totaling 0 shares. Insiders that have sold shares include ISLAM SAQIB, EDRIS BADREDDIN, and LYNCH DANIEL.

Which insider recently purchased SWTX stock?

There have been 0 transaction(s) during the past 6-months in which SpringWorks Therapeutics, Inc. insiders have bought stock, totalling 0 shares

How much of SWTX does insiders own?

Around 0 SpringWorks Therapeutics, Inc. shares are held by insiders, which represents about 1.28% of SWTX stock.

Who is the insider with the largest stake?

SWTX , OrbiMed Capital GP VI LLC holds the largest portfolio of the company's shares. SWTX shares owned by OrbiMed total nearly 5.75 million.

Which institution holds the most shares in SWTX?

CHARLES SCHWAB INVESTMENT MANAGEMENT INC is the largest institutional owner in SWTX which holds 432.62 thousand shares worth $20.33M or 0.58% of the total SWTX shares outstanding followed by SOROS FUND MANAGEMENT LLC with ownership of 501.99 thousand shares representing 0.67% of the SWTX ownership. MILLENNIUM MANAGEMENT LLC is the third largest stakeholder with 544.86 thousand shares or 0.73% of the ownership worth more than $25.60M.

Is SpringWorks Therapeutics, Inc. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the SWTX is concerned, it is a stock which is optionable.

Is there a short position on SWTX's shares?

Number of SWTX shares short is 6.24M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding SWTX shares are there?

As of today, 75.35M shares of SWTX are outstanding.

Is there many float in SWTX stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, SWTX has 74.16M shares in float.

SWTX short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for SWTX is 1.18.

SpringWorks Therapeutics (SWTX) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableNo

OptionableYes

Short Percent Of Outstanding Shares8.29

Short Percent Of Float9.97

Shares Outstanding75.35M

Shares Float74.16M

Shares Short6.24M

Short Ratio1.18

9.97%

Short % of Float

8.29%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

1.28% Percentage of Shares held by All Insiders

87.4% Percentage of Shares held by All Institutions

88.54% Percentage of Float held by Institutions

413

Number of Institutions Holding Shares

Institutional Ownership

About 87.4% of SWTX shares are held by financial institutions. CHARLES SCHWAB INVESTMENT MANAGEMENT INC is the top corporate investor, holding 432.62K shares valued at $20.33M. A 0.58% stake in SpringWorks Therapeutics, Inc. is owned by the company. SOROS FUND MANAGEMENT LLC owns 501.99K shares valued at $23.59M, which translates its holding of 0.67% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.58%	432.62K	20.33M	-182.26K	-29.64%
Jun 30, 2025	SOROS FUND MANAGEMENT LLC	0.67%	501.99K	23.59M	45.16K	+9.88%
Jun 30, 2025	MILLENNIUM MANAGEMENT LLC	0.73%	544.86K	25.6M	40.99K	+8.13%
Jun 30, 2025	HUDSON BAY CAPITAL MANAGEMENT LP	0.73%	547.01K	25.7M	13.4K	+2.51%
Jun 30, 2025	SAND GROVE CAPITAL MANAGEMENT LLP	0.76%	572.39K	26.9M	572.39K	+100.00%
Jun 30, 2025	ROYAL BANK OF CANADA	0.78%	585.12K	27.5M	491.91K	+527.73%
Jun 30, 2025	ARROWMARK COLORADO HOLDINGS LLC	0.82%	617.02K	28.99M	-842.05K	-57.71%
Jun 30, 2025	GLAZER CAPITAL, LLC	5.48%	4.11M	193.04M	4.11M	+100.00%
Jun 30, 2025	TIG ADVISORS, LLC	3.49%	2.61M	122.69M	2.36M	+937.48%
Jun 30, 2025	VANGUARD GROUP INC	9.52%	7.13M	335.09M	48.42K	+0.68%
Jun 30, 2025	BLACKROCK, INC.	9.7%	7.26M	341.18M	1.01M	+16.24%
Jun 30, 2025	VERITION FUND MANAGEMENT LLC	0.42%	313.41K	14.73M	154.62K	+97.38%
Jun 30, 2025	BERYL CAPITAL MANAGEMENT LLC	2.83%	2.12M	99.5M	2.12M	+100.00%
Jun 30, 2025	NORGES BANK	2.42%	1.82M	85.29M	981.61K	+117.77%
Jun 30, 2025	CITADEL ADVISORS LLC	0.77%	573.7K	26.96M	178.2K	+45.06%
Jun 30, 2025		0.86%	645K	30.31M	645K	+100.00%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.65%	484.87K	22.78M	-138.79K	-22.25%
Jun 30, 2025	HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND	0.47%	355K	16.68M	355K	+100.00%
Jun 30, 2025	JANUS HENDERSON GROUP PLC	0.51%	383.7K	18.04M	356.68K	+1,319.80%
Jun 30, 2025	UBS GROUP AG	0.52%	392.88K	18.46M	-233.55K	-37.28%
Jun 30, 2025	UBS OCONNOR LLC	1.85%	1.39M	65.11M	1.35M	+3,455.53%
Jun 30, 2025	WOODLINE PARTNERS LP	0.58%	437K	20.53M	-1.71M	-79.63%
Jun 30, 2025	MORGAN STANLEY	1.67%	1.25M	58.63M	352.21K	+39.33%
Jun 30, 2025	NORTHERN TRUST CORP	0.86%	644.63K	30.29M	7.19K	+1.13%
Jun 30, 2025	ODDO BHF ASSET MANAGEMENT SAS	0.86%	645K	30.31M	645K	+100.00%
Jun 30, 2025	GABELLI FUNDS LLC	0.91%	683.2K	32.1M	643.14K	+1,605.44%
Jun 30, 2025	HARVEST MANAGEMENT LLC	0.92%	687.5K	32.31M	544K	+379.09%
Jun 30, 2025	WATER ISLAND CAPITAL LLC	0.94%	703.53K	33.06M	703.53K	+100.00%
Jun 30, 2025	BALYASNY ASSET MANAGEMENT L.P.	0.94%	705.36K	33.15M	88.64K	+14.37%
Jun 30, 2025	RENAISSANCE TECHNOLOGIES LLC	1.02%	760.6K	35.74M	574.7K	+309.14%
Jun 30, 2025	KRYGER CAPITAL LTD	1.02%	765.52K	35.97M	683.86K	+837.42%
Jun 30, 2025	TRIUM CAPITAL LLP	1.05%	787.46K	37M	787.46K	+100.00%
Jun 30, 2025	WHITEBOX ADVISORS LLC	1.06%	795.19K	37.37M	795.19K	+100.00%
Jun 30, 2025	LMR PARTNERS LLP	1.34%	1M	46.99M	900K	+900.00%
Jun 30, 2025	PENTWATER CAPITAL MANAGEMENT LP	1.34%	1M	46.99M	500K	+100.00%
Jun 30, 2025	PRINCIPAL FINANCIAL GROUP INC	1.34%	1M	47.15M	-60.71K	-5.71%
Jun 30, 2025	JPMORGAN CHASE & CO	1.53%	1.15M	53.99M	1.09M	+1,742.27%
Jun 30, 2025	ALPINE ASSOCIATES MANAGEMENT INC.	1.53%	1.15M	53.99M	949.5K	+475.94%
Jun 30, 2025	AQR ARBITRAGE LLC	1.76%	1.32M	62.02M	1.32M	+100.00%
Jun 30, 2025	NEXPOINT ASSET MANAGEMENT, L.P.	2.11%	1.58M	74.39M	1.58M	+100.00%
Jun 30, 2025	CITIGROUP INC	2.13%	1.59M	74.78M	1.45M	+1,019.51%
Jun 30, 2025	BARCLAYS PLC	2.18%	1.63M	76.72M	703.8K	+75.77%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.39%	1.79M	84.1M	74K	+4.31%
Jun 30, 2025	FIRST TRUST CAPITAL MANAGEMENT L.P.	2.6%	1.94M	91.34M	1.94M	+100.00%
Jun 30, 2025	MAGNETAR FINANCIAL LLC	2.74%	2.05M	96.45M	2.05M	+100.00%
Jun 30, 2025	CALAMOS ADVISORS LLC	0.43%	318.5K	14.06M	318.5K	+100.00%
Jun 30, 2025	GABELLI & CO INVESTMENT ADVISERS, INC.	0.43%	324.35K	15.24M	282.1K	+667.69%
Jun 30, 2025	P SCHOENFELD ASSET MANAGEMENT LP	0.47%	351.4K	16.51M	351.4K	+100.00%
Jun 30, 2025	ALLIANCEBERNSTEIN L.P.	1.8%	1.35M	63.46M	1.25M	+1,290.98%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	3.04%	2.28M	106.92M	1.65M	+263.44%
Jun 30, 2025	STATE STREET CORP	4%	2.99M	140.69M	77.66K	+2.66%
Jun 30, 2025	FIL LTD	4.02%	3.01M	141.63M	3.01M	+100.00%
Mar 31, 2025	VOYA INVESTMENT MANAGEMENT LLC	1.17%	876.55K	38.68M	79.86K	+10.02%
Mar 31, 2025	UBS GROUP AG	0.84%	626.43K	27.64M	404.25K	+181.95%
Mar 31, 2025	STATE STREET CORP	3.89%	2.92M	128.7M	-84.65K	-2.82%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.29%	1.72M	75.72M	45.24K	+2.71%
Mar 31, 2025	BARCLAYS PLC	1.24%	928.82K	40.99M	772.7K	+494.93%
Mar 31, 2025	MORGAN STANLEY	1.2%	895.58K	39.52M	-1.1M	-55.16%
Mar 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	3.45%	2.58M	113.98M	-692.05K	-21.13%
Mar 31, 2025	PICTET ASSET MANAGEMENT HOLDING SA	2.23%	1.67M	73.71M	-721.4K	-30.17%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	1.1%	822.81K	36.31M	405.92K	+97.37%
Mar 31, 2025	FINEPOINT CAPITAL LP	0.97%	728.6K	32.15M	-20.15K	-2.69%
Mar 31, 2025	DIMENSIONAL FUND ADVISORS LP	0.74%	555.89K	24.54M	-161.83K	-22.55%
Mar 31, 2025	HUDSON BAY CAPITAL MANAGEMENT LP	0.71%	533.61K	23.55M	478.11K	+861.46%
Mar 31, 2025	ORACLE INVESTMENT MANAGEMENT INC	0.71%	531.35K	23.45M	276.58K	+108.56%
Mar 31, 2025	POLAR CAPITAL HOLDINGS PLC	2.34%	1.75M	77.23M	250K	+16.67%
Mar 31, 2025	AMERIPRISE FINANCIAL INC	0.96%	717.91K	31.68M	-253.19K	-26.07%
Mar 31, 2025	NORTHERN TRUST CORP	0.85%	637.45K	28.13M	-18.23K	-2.78%
Mar 31, 2025	WOODLINE PARTNERS LP	2.86%	2.14M	94.65M	654.68K	+43.93%
Mar 31, 2025	FIERA CAPITAL CORP	1.63%	1.22M	54.02M	5.02K	+0.41%
Mar 31, 2025	WALLEYE TRADING LLC	0.83%	622.4K	27.47M	622.4K	+100.00%
Mar 31, 2025	BALYASNY ASSET MANAGEMENT L.P.	0.82%	616.73K	27.22M	530.97K	+619.12%
Mar 31, 2025	ARROWMARK COLORADO HOLDINGS LLC	1.95%	1.46M	64.39M	-40.06K	-2.67%
Mar 31, 2025	PRINCIPAL FINANCIAL GROUP INC	1.42%	1.06M	46.96M	-39.75K	-3.60%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.82%	614.89K	27.13M	9.64K	+1.59%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.84%	626.1K	27.63M	286.18K	+84.19%
Mar 31, 2025	SCHRODER INVESTMENT MANAGEMENT GROUP	0.8%	599.89K	28.44M	431.68K	+256.64%
Mar 31, 2025	FMR LLC	14.96%	11.2M	494.47M	46.84K	+0.42%
Mar 31, 2025	VANGUARD GROUP INC	9.46%	7.08M	312.55M	-76.29K	-1.07%
Mar 31, 2025	BLACKROCK, INC.	8.34%	6.25M	275.64M	285.71K	+4.79%
Mar 31, 2025	MASSACHUSETTS FINANCIAL SERVICES CO /MA/	0.47%	354.51K	15.64M	-238.14K	-40.18%
Mar 31, 2025		0.41%	307.6K	13.57M	307.6K	+100.00%
Mar 31, 2025	INVESCO LTD.	0.7%	521.37K	23.01M	-35.7K	-6.41%
Mar 31, 2025	D. E. SHAW & CO., INC.	2.22%	1.66M	73.41M	1.28M	+329.03%
Mar 31, 2025	ORBIMED ADVISORS LLC	1.27%	950.2K	41.93M	-304.83K	-24.29%
Mar 31, 2025	GW&K INVESTMENT MANAGEMENT, LLC	1.16%	868.94K	38.35M	-105.44K	-10.82%
Mar 31, 2025	MAVERICK CAPITAL LTD	0.62%	463.83K	20.47M	-2.43M	-83.96%
Mar 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.83%	623.66K	27.52M	486.64K	+355.15%
Mar 31, 2025	DUQUESNE FAMILY OFFICE LLC	0.82%	615.93K	27.18M	-243.77K	-28.35%
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	0.67%	503.87K	22.24M	503.87K	+100.00%
Mar 31, 2025	PENTWATER CAPITAL MANAGEMENT LP	0.67%	500K	22.07M	500K	+100.00%
Mar 31, 2025	SOROS FUND MANAGEMENT LLC	0.61%	456.83K	20.16M	-143.64K	-23.92%
Mar 31, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.59%	444.37K	19.61M	308.29K	+226.55%
Mar 31, 2025	VICTORY CAPITAL MANAGEMENT INC	0.58%	432.95K	19.11M	-181.97K	-29.59%
Mar 31, 2025	CITADEL ADVISORS LLC	0.53%	395.5K	17.45M	392.1K	+11,532.35%
Mar 31, 2025	LORD, ABBETT & CO. LLC	0.5%	373.87K	16.5M	-571.93K	-60.47%
Mar 31, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.49%	365.86K	16.15M	1.8K	+0.49%
Mar 31, 2024	PEREGRINE CAPITAL MANAGEMENT LLC	0.18%	116.65K	5.74M	-19.36K	-14.24%
Mar 31, 2024	MILLENNIUM MANAGEMENT LLC	1.12%	705.54K	34.73M	671.33K	+1,962.68%
Mar 31, 2024	D. E. SHAW & CO., INC.	1.03%	648.85K	31.94M	518.54K	+397.92%
Mar 31, 2024	FINEPOINT CAPITAL LP	0.94%	592.53K	29.16M	35.6K	+6.39%
Mar 31, 2024	NORTHERN TRUST CORP	0.94%	590.72K	29.08M	-660	-0.11%
Mar 31, 2024	MORGAN STANLEY	0.92%	581.06K	28.6M	10.4K	+1.82%
Mar 31, 2024	FMR LLC	17.53%	11.07M	544.77M	258.79K	+2.39%
Mar 31, 2024	VANGUARD GROUP INC	10.34%	6.53M	321.37M	492.78K	+8.16%
Mar 31, 2024	MAVERICK CAPITAL LTD	3.02%	1.91M	93.94M	-964.59K	-33.57%
Mar 31, 2024	ARROWMARK COLORADO HOLDINGS LLC	2.73%	1.72M	84.78M	-374.43K	-17.86%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	2.38%	1.5M	74.07M	85.62K	+6.03%
Mar 31, 2024	FIERA CAPITAL CORP	1.45%	917.28K	45.15M	23.82K	+2.67%
Mar 31, 2024	DIMENSIONAL FUND ADVISORS LP	1.43%	905.74K	44.58M	-62.67K	-6.47%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.29%	182.81K	9M	-1.34K	-0.72%
Mar 31, 2024	POINT72 ASSET MANAGEMENT, L.P.	2.36%	1.49M	73.33M	-672.36K	-31.10%
Mar 31, 2024	ARTAL GROUP S.A.	2.24%	1.42M	69.66M	-200K	-12.38%
Mar 31, 2024	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	2.03%	1.28M	63.16M	-1.3M	-50.35%
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	6.51%	4.11M	202.32M	1.33M	+48.04%
Mar 31, 2024	DEEP TRACK CAPITAL, LP	5.51%	3.48M	171.28M	-583.82K	-14.37%
Mar 31, 2024	BOXER CAPITAL, LLC	5.42%	3.42M	168.41M	0	0
Mar 31, 2024	MARSHALL WACE, LLP	4.7%	2.97M	146.02M	-58.24K	-1.93%
Mar 31, 2024	STATE STREET CORP	4.69%	2.96M	145.77M	341.97K	+13.05%
Mar 31, 2024	LORD, ABBETT & CO. LLC	3.67%	2.32M	114.08M	2.32M	+100.00%
Mar 31, 2024	PERCEPTIVE ADVISORS LLC	3.58%	2.26M	111.36M	305.22K	+15.59%
Mar 31, 2024	ORBIMED ADVISORS LLC	2.7%	1.71M	84.03M	-1.51M	-46.97%
Mar 31, 2024	PICTET ASSET MANAGEMENT HOLDING SA	2.56%	1.62M	79.55M	57.67K	+3.70%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	1.63%	1.03M	50.49M	670.48K	+188.68%
Mar 31, 2024	WOODLINE PARTNERS LP	1.37%	867.22K	42.68M	65.04K	+8.11%
Mar 31, 2024	CITADEL ADVISORS LLC	1.13%	710.27K	34.96M	292.45K	+70.00%
Mar 31, 2024	JANE STREET GROUP, LLC	0.92%	580.94K	28.59M	459.34K	+377.76%
Mar 31, 2024	VOYA INVESTMENT MANAGEMENT LLC	0.92%	580.1K	28.55M	534.58K	+1,174.38%
Mar 31, 2024	AMERIPRISE FINANCIAL INC	0.88%	557.62K	27.45M	37.37K	+7.18%
Mar 31, 2024	JPMORGAN CHASE & CO	0.86%	543.03K	26.73M	-72.19K	-11.73%
Mar 31, 2024	INVESCO LTD.	0.84%	532.33K	26.2M	373.8K	+235.80%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.82%	517.97K	25.49M	16.91K	+3.37%
Mar 31, 2024	VICTORY CAPITAL MANAGEMENT INC	0.8%	507.33K	24.97M	137.96K	+37.35%
Mar 31, 2024	MASSACHUSETTS FINANCIAL SERVICES CO /MA/	0.74%	465.86K	22.93M	-2.22K	-0.47%
Mar 31, 2024	RUBRIC CAPITAL MANAGEMENT LP	0.68%	426.77K	21.01M	426.77K	+100.00%
Mar 31, 2024	ORACLE INVESTMENT MANAGEMENT INC	0.67%	421.58K	20.75M	264.5K	+168.38%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.59%	374.1K	18.41M	-87.17K	-18.90%
Mar 31, 2024	LAURION CAPITAL MANAGEMENT LP	0.59%	372.07K	18.31M	0	0
Mar 31, 2024	POLAR CAPITAL HOLDINGS PLC	0.55%	350K	17.23M	350K	+100.00%
Mar 31, 2024	NEW YORK STATE COMMON RETIREMENT FUND	0.4%	253.7K	12.49M	-38	-0.02%
Mar 31, 2024	TD ASSET MANAGEMENT INC	0.4%	253.63K	12.48M	72.2K	+39.79%
Mar 31, 2024	SCHONFELD STRATEGIC ADVISORS LLC	0.38%	242.17K	11.92M	-224.28K	-48.08%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.38%	238.55K	11.74M	107.89K	+82.57%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.37%	232.8K	11.46M	-8.32K	-3.45%
Mar 31, 2024	UBS GROUP AG	0.34%	213.53K	10.51M	73.86K	+52.88%
Mar 31, 2024	SOROS FUND MANAGEMENT LLC	0.32%	203.95K	10.04M	203.95K	+100.00%
Mar 31, 2024	CANDRIAM S.C.A.	0.32%	200.63K	9.87M	-75K	-27.21%
Mar 31, 2024	BESSEMER GROUP INC	0.29%	182.36K	8.98M	-58.98K	-24.44%
Mar 31, 2024	RAFFERTY ASSET MANAGEMENT, LLC	0.28%	179.57K	8.84M	35.22K	+24.40%
Mar 31, 2024	RUSSELL INVESTMENTS GROUP, LTD.	0.27%	170.05K	8.37M	55.89K	+48.96%
Mar 31, 2024	CITIGROUP INC	0.26%	163.55K	8.05M	83.77K	+105.01%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.23%	145.03K	7.14M	35.65K	+32.59%
Mar 31, 2024	ALTITUDE CREST PARTNERS INC.	0.2%	128.84K	6.34M	128.84K	+100.00%
Mar 31, 2024	BLACKROCK INC.	8.62%	5.44M	267.7M	56.67K	+1.05%
Mar 31, 2024	M28 CAPITAL MANAGEMENT LP	0.17%	110.4K	5.43M	-32.4K	-22.69%
Mar 31, 2024	GW&K INVESTMENT MANAGEMENT, LLC	0.17%	109.6K	5.39M	109.6K	+100.00%
Mar 31, 2024	WELLS FARGO & COMPANY/MN	0.17%	104.52K	5.14M	6.29K	+6.40%
Mar 31, 2024	ENSIGN PEAK ADVISORS, INC	0.16%	101.79K	5.01M	81.79K	+408.96%
Mar 31, 2024	AFFINITY ASSET ADVISORS, LLC	0.16%	100K	4.92M	0	0
Mar 31, 2024	RHUMBLINE ADVISERS	0.16%	99.58K	4.9M	4.51K	+4.75%
Mar 31, 2024	SWISS NATIONAL BANK	0.15%	92.4K	4.55M	0	0
Mar 31, 2024	MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC	0.13%	82.66K	4.07M	18.44K	+28.72%
Mar 31, 2024	ENVESTNET ASSET MANAGEMENT INC	0.11%	71.65K	3.53M	5.52K	+8.34%
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	0.11%	69.53K	3.42M	3.14K	+4.73%
Mar 31, 2024	JEFFERIES FINANCIAL GROUP INC.	0.11%	68.67K	3.38M	-287.41K	-80.72%
Mar 31, 2024	CREDIT SUISSE AG/	0.09%	59.2K	2.91M	22.18K	+59.91%
Mar 31, 2024	STATE OF NEW JERSEY COMMON PENSION FUND D	0.09%	57.51K	2.83M	57.51K	+100.00%
Mar 31, 2024	ALPS ADVISORS INC	0.08%	52.05K	2.56M	10.72K	+25.92%
Mar 31, 2024	ASSENAGON ASSET MANAGEMENT S.A.	0.08%	50.98K	2.51M	50.98K	+100.00%
Mar 31, 2024	LEGAL & GENERAL GROUP PLC	0.08%	50.81K	2.5B	1.14K	+2.30%
Mar 31, 2024	SEI INVESTMENTS CO	0.08%	48.66K	2.4B	21.56K	+79.54%
Mar 31, 2024	LIGHTHOUSE INVESTMENT PARTNERS, LLC	0.06%	40.73K	2M	12.72K	+45.42%
Dec 31, 2023	DEEP TRACK CAPITAL, LP	6.5%	4.06M	148.32M	517.24K	+14.58%
Dec 31, 2023	BLACKROCK INC.	8.61%	5.38M	196.45M	956.45K	+21.61%
Dec 31, 2023	VANGUARD GROUP INC	9.66%	6.04M	220.33M	1.11M	+22.63%
Dec 31, 2023	FMR LLC	17.29%	10.81M	394.54M	1.42M	+15.17%
Dec 31, 2023	BARCLAYS PLC	0.25%	154.27K	5.63M	56.36K	+57.56%
Dec 31, 2023	ORACLE INVESTMENT MANAGEMENT INC	0.25%	157.08K	5.73M	157.08K	+100.00%
Dec 31, 2023	INVESCO LTD.	0.25%	158.52K	5.79M	128.13K	+421.53%
Dec 31, 2023	SPHERA FUNDS MANAGEMENT LTD.	0.27%	170.27K	6.21M	-149.64K	-46.78%
Dec 31, 2023	TD ASSET MANAGEMENT INC	0.29%	181.43K	6.62M	42.6K	+30.68%
Dec 31, 2023	NUVEEN ASSET MANAGEMENT, LLC	0.29%	184.15K	6.72M	34.95K	+23.43%
Dec 31, 2023	DARWIN GLOBAL MANAGEMENT, LTD.	0.31%	192.73K	7.03M	192.73K	+100.00%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.39%	241.12K	8.8M	23.5K	+10.80%
Dec 31, 2023	BESSEMER GROUP INC	0.39%	241.34K	8.81M	0	0
Dec 31, 2023	NEW YORK STATE COMMON RETIREMENT FUND	0.41%	253.74K	9.26M	3.99K	+1.60%
Dec 31, 2023	CANDRIAM S.C.A.	0.44%	275.63K	10.06M	125K	+82.99%
Dec 31, 2023	NORGES BANK	0.54%	337.83K	12.33M	337.83K	+100.00%
Dec 31, 2023	CAPTION MANAGEMENT, LLC	0.54%	337.9K	12.33M	337.9K	+100.00%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.57%	355.35K	12.97M	-393.93K	-52.57%
Dec 31, 2023	JEFFERIES FINANCIAL GROUP INC.	0.57%	356.08K	13M	356.08K	+100.00%
Dec 31, 2023	VICTORY CAPITAL MANAGEMENT INC	0.59%	369.37K	13.48M	328.13K	+795.65%
Dec 31, 2023	LAURION CAPITAL MANAGEMENT LP	0.6%	372.07K	13.58M	479	+0.13%
Dec 31, 2023	CITADEL ADVISORS LLC	0.67%	417.81K	15.25M	396.51K	+1,861.02%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.74%	461.28K	16.84M	-131.2K	-22.14%
Dec 31, 2023	SCHONFELD STRATEGIC ADVISORS LLC	0.75%	466.46K	17.03M	466.46K	+100.00%
Dec 31, 2023	MASSACHUSETTS FINANCIAL SERVICES CO /MA/	0.75%	468.08K	17.08M	60.65K	+14.89%
Dec 31, 2023	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.8%	500.75K	18.28M	426.25K	+572.12%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.8%	501.07K	18.29M	77.3K	+18.24%
Dec 31, 2023	AMERIPRISE FINANCIAL INC	0.83%	520.26K	18.99M	295.53K	+131.51%
Dec 31, 2023	FINEPOINT CAPITAL LP	0.89%	556.93K	20.33M	0	0
Dec 31, 2023	MORGAN STANLEY	0.91%	570.66K	20.83M	42.7K	+8.09%
Dec 31, 2023	NORTHERN TRUST CORP	0.95%	591.38K	21.59M	70.13K	+13.45%
Dec 31, 2023	JPMORGAN CHASE & CO	0.98%	615.22K	22.46M	48.3K	+8.52%
Dec 31, 2023	RTW INVESTMENTS, LP	1%	625K	22.81M	625K	+100.00%
Dec 31, 2023	WOODLINE PARTNERS LP	1.28%	802.18K	29.28M	610.81K	+319.17%
Dec 31, 2023	FIERA CAPITAL CORP	1.43%	893.46K	32.61M	522	+0.06%
Dec 31, 2023	DIMENSIONAL FUND ADVISORS LP	1.55%	968.41K	35.35M	-42.96K	-4.25%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	2.27%	1.42M	51.8M	236.98K	+20.05%
Dec 31, 2023		0.54%	340K	12.41M	340K	+100.00%
Dec 31, 2023	ARTAL GROUP S.A.	2.58%	1.62M	58.96M	-201.27K	-11.08%
Dec 31, 2023	PERCEPTIVE ADVISORS LLC	3.13%	1.96M	71.44M	436.83K	+28.73%
Dec 31, 2023	ARROWMARK COLORADO HOLDINGS LLC	3.35%	2.1M	76.53M	-299.47K	-12.50%
Dec 31, 2023	POINT72 ASSET MANAGEMENT, L.P.	3.46%	2.16M	78.92M	1.64M	+310.71%
Dec 31, 2023	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	4.13%	2.58M	94.33M	1M	+63.61%
Dec 31, 2023	STATE STREET CORP	4.19%	2.62M	95.62M	48.45K	+1.88%
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	4.44%	2.78M	101.35M	1.22M	+78.50%
Dec 31, 2023	MAVERICK CAPITAL LTD	4.6%	2.87M	104.87M	2.24M	+350.52%
Dec 31, 2023	MARSHALL WACE, LLP	4.84%	3.02M	110.41M	1.74M	+134.80%
Dec 31, 2023	ORBIMED ADVISORS LLC	5.15%	3.22M	117.51M	-749.23K	-18.88%
Dec 31, 2023	BOXER CAPITAL, LLC	5.47%	3.42M	124.89M	0	0

Insiders

Among the SWTX insiders holding of 1.28% of the stake in company, ORBIMED CAPITAL GP VI LLC, , holds the largest shares of 5.75M. ORBIMED ADVISORS LLC, 10 percent owner, is the second largest SWTX insider with ownership of 5.6M shares. BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC, 10 percent owner, stands third with possession of 4.83M shares of that stake.

Insiders	Designation	Shares Held
ORBIMED CAPITAL GP VI LLC		5.75M
ORBIMED ADVISORS LLC	10 percent owner	5.6M
BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	10 percent owner	4.83M
LEWIS-HALL FREDA C		4.59M
PFIZER INC	10 percent owner	4.59M
SCHWARTZ JEFFREY LAWRENCE	director	3.08M
ISLAM SAQIB	Chief Executive Officer	954.87K
EDRIS BADREDDIN	Chief Operating Officer	169.71K
SMITH L. MARY	Chief Development Officer	167.51K
SQUINTO STEPHEN P		125.73K
AUSTIN MAURY	CFO	100K
LYNCH DANIEL	director	82.94K
ASHAR BHAVESH	Chief Commercial Officer	62.05K
PICHL DANIEL	Chief People Officer	50.76K
SEIFERT MICHAEL E	Sr. VP Finance/CFO	5K
HAMBLETON JULIE	director	4.1K
PFEFFER MATTHEW J	director	0

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Mar 03, 2025	ISLAM SAQIB	SALE	56.89	600	34.13K	954.87K
Mar 03, 2025	EDRIS BADREDDIN	SALE	56.20	400	22.48K	169.71K
Feb 20, 2025	LYNCH DANIEL	SALE	61.24	3.58K	219.35K	82.94K
Feb 20, 2025	ISLAM SAQIB	SALE	61.24	5.07K	310.35K	1.03M
Feb 20, 2025	ASHAR BHAVESH	SALE	61.19	1.02K	62.17K	62.05K
Feb 14, 2025	ISLAM SAQIB	SALE	59.92	10.67K	639.49K	1.06M
Feb 14, 2025	LYNCH DANIEL	SALE	60.00	400	24K	130.54K
Feb 10, 2025	PICHL DANIEL	SALE	57.15	7K	400.07K	50.76K
Feb 10, 2025	EDRIS BADREDDIN	SALE	53.13	30K	1.59M	189.71K
Feb 10, 2025	HAMBLETON JULIE	SALE	53.01	13.77K	730.21K	4.1K
Feb 10, 2025	ISLAM SAQIB	SALE	53.30	48K	2.56M	1M
Feb 10, 2025	LYNCH DANIEL	SALE	55.51	65.6K	3.64M	130.94K
Dec 03, 2024	EDRIS BADREDDIN	SALE	42.24	8.03K	339.39K	209.6K
Dec 02, 2024	ISLAM SAQIB	SALE	41.85	3.99K	166.94K	1.01M
Sep 03, 2024	EDRIS BADREDDIN	SALE	42.08	3.08K	129.59K	229.6K
Sep 03, 2024	ISLAM SAQIB	SALE	42.07	6.69K	281.55K	1.06M
Jun 03, 2024	ISLAM SAQIB	SALE	42.09	400	16.84K	1.11M
Jun 03, 2024	HAMBLETON JULIE	SALE	42.09	20	841.81	4.1K
Jun 03, 2024	EDRIS BADREDDIN	SALE	42.04	385	16.18K	249.6K
Feb 16, 2024	PICHL DANIEL	SALE	50.10	15K	751.55K	45.21K
Feb 05, 2024	ASHAR BHAVESH	SALE	49.32	4.83K	238.43K	58.15K
Feb 02, 2024	ASHAR BHAVESH	SALE	46.37	88	4.08K	62.99K
Feb 02, 2024	PICHL DANIEL	SALE	46.44	743	34.51K	45.21K
Jul 19, 2023	HAMBLETON JULIE	SALE	29.31	2.42K	70.88K	4.65K
Jun 20, 2023	HAMBLETON JULIE	SALE	26.92	2.4K	64.6K	7.07K
Mar 16, 2023	SCHWARTZ JEFFREY LAWRENCE	SALE	28.50	1.75M	49.88M	3.08M
Mar 15, 2023	HAMBLETON JULIE	SALE	31.50	1.11K	34.84K	4.82K
Jan 26, 2023	PICHL DANIEL	SALE	31.00	858	26.6K	35.2K
Sep 12, 2022	ORBIMED ADVISORS LLC	SALE	31.98	30K	959.4K	5.6M
Aug 09, 2022	ORBIMED ADVISORS LLC	SALE	37.47	69.57K	2.61M	5.75M
Aug 08, 2022	ORBIMED ADVISORS LLC	SALE	38.33	205K	7.86M	5.82M
Aug 08, 2022	ORBIMED CAPITAL GP VI LLC	SALE	37.47	69.57K	2.61M	5.75M
Oct 20, 2021	ISLAM SAQIB	SALE	58.67	10.08K	591.53K	779.22K
Oct 19, 2021	ISLAM SAQIB	SALE	58.81	14.08K	827.87K	769.14K
Oct 18, 2021	ISLAM SAQIB	SALE	58.59	38.34K	2.25M	783.21K
Oct 13, 2021	SMITH L. MARY	SALE	55.97	10K	559.68K	167.51K
Aug 10, 2021	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	SALE	70.25	1M	70.25M	4.83M
Jul 20, 2021	ISLAM SAQIB	SALE	77.68	18.57K	1.44M	821.55K
Jul 19, 2021	ISLAM SAQIB	SALE	76.09	43.93K	3.34M	840.12K
Jul 13, 2021	SMITH L. MARY	SALE	80.88	10K	808.78K	167.51K
Jul 01, 2021	ORBIMED ADVISORS LLC	SALE	85.01	15.96K	1.36M	6.03M
Jul 01, 2021	EDRIS BADREDDIN	SALE	85.35	32K	2.73M	301.54K
Jun 28, 2021	ORBIMED ADVISORS LLC	SALE	85.17	6.5K	553.78K	6.04M
Jun 25, 2021	ORBIMED ADVISORS LLC	SALE	85.14	22.33K	1.9M	6.05M
Jun 24, 2021	ORBIMED ADVISORS LLC	SALE	85.22	34.2K	2.91M	6.07M
Jun 23, 2021	ORBIMED ADVISORS LLC	SALE	85.00	100	8.5K	6.11M
Jun 10, 2021	ORBIMED ADVISORS LLC	SALE	85.09	30.85K	2.63M	6.11M
Jun 09, 2021	ORBIMED ADVISORS LLC	SALE	85.33	5.05K	430.83K	6.14M
Jun 08, 2021	ORBIMED ADVISORS LLC	SALE	85.37	42.63K	3.64M	6.14M
Jun 07, 2021	ORBIMED ADVISORS LLC	SALE	84.90	371	31.5K	6.19M
Apr 28, 2021	SQUINTO STEPHEN P	SALE	76.20	19.23K	1.47M	125.73K
Apr 27, 2021	SQUINTO STEPHEN P	SALE	75.05	201	15.09K	144.96K
Apr 20, 2021	ISLAM SAQIB	SALE	66.39	24.08K	1.6M	884.05K
Apr 19, 2021	ISLAM SAQIB	SALE	69.04	38.43K	2.65M	908.13K
Apr 15, 2021	SQUINTO STEPHEN P	SALE	75.01	1.06K	79.29K	145.16K
Apr 14, 2021	SQUINTO STEPHEN P	SALE	75.08	511	38.36K	146.22K
Apr 13, 2021	SMITH L. MARY	SALE	68.07	10K	680.72K	167.51K
Mar 09, 2021	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	SALE	71.50	1.45M	103.68M	5.83M
Mar 01, 2021	ORBIMED ADVISORS LLC	SALE	83.19	1.22M	101.49M	6.19M
Jan 25, 2021	EDRIS BADREDDIN	SALE	84.07	32K	2.69M	261.54K
Jan 20, 2021	SMITH L. MARY	SALE	78.70	10K	787.02K	167.51K
Jan 20, 2021	ISLAM SAQIB	SALE	78.75	2.2K	173.18K	1.22M
Jan 19, 2021	ISLAM SAQIB	SALE	78.54	60.3K	4.74M	1.23M
Sep 17, 2019	ORBIMED ADVISORS LLC	PURCHASE	18.00	275K	4.95M	7.41M
Sep 17, 2019	SQUINTO STEPHEN P	PURCHASE	18.00	275K	4.95M	7.41M
Sep 17, 2019	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	PURCHASE	18.00	150K	2.7M	7.28M
Sep 17, 2019	PFIZER INC	PURCHASE	18.00	50K	900K	4.59M
Sep 17, 2019	LEWIS-HALL FREDA C	PURCHASE	18.00	50K	900K	4.59M
Jan 06, 2009	PFEFFER MATTHEW J	PURCHASE	1.30	10K	13K	0
Mar 01, 2005	AUSTIN MAURY	PURCHASE	1.30	50K	65K	100K
Aug 19, 2003	SEIFERT MICHAEL E	PURCHASE	1.53	5K	7.64K	5K

Frequently Asked Questions