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Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.
Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.
About 91.98% of SLRN shares are held by financial institutions. OPALEYE MANAGEMENT INC. is the top corporate investor, holding 1.62M shares valued at $3.99M. A 1.63% stake in Acelyrin, Inc. is owned by the company. STATE STREET CORP owns 1.42M shares valued at $3.51M, which translates its holding of 1.41% of the stake in the company.
| Date | Holder | % Stake | Shares Held | Total Value ($) | Shares | % Change in Portfolio |
|---|---|---|---|---|---|---|
| Mar 31, 2025 | OPALEYE MANAGEMENT INC. | 1.63% | 1.62M | 3.99M | -620K | -27.74% |
| Mar 31, 2025 | STATE STREET CORP | 1.41% | 1.42M | 3.51M | -21.21K | -1.47% |
| Mar 31, 2025 | TOWERVIEW LLC | 0.54% | 540K | 1.33M | 540K | +100.00% |
| Mar 31, 2025 | GOLDMAN SACHS GROUP INC | 0.35% | 351.41K | 867.98K | -218.5K | -38.34% |
| Mar 31, 2025 | LOS ANGELES CAPITAL MANAGEMENT LLC | 0.11% | 109.61K | 270.74K | -12.39K | -10.16% |
| Mar 31, 2025 | INVESCO LTD. | 0.08% | 85.52K | 211.24K | 59.75K | +231.91% |
| Mar 31, 2025 | 0.2% | 202.24K | 499.53K | 202.24K | +100.00% | |
| Mar 31, 2025 | MADISON AVENUE PARTNERS, LP | 4.17% | 4.14M | 10.23M | 4.14M | +100.00% |
| Mar 31, 2025 | ORBIMED ADVISORS LLC | 4.03% | 4M | 9.88M | 0 | 0 |
| Mar 31, 2025 | MORGAN STANLEY | 0.27% | 275.82K | 681.26K | -2.05M | -88.13% |
| Mar 31, 2025 | GEODE CAPITAL MANAGEMENT, LLC | 1.76% | 1.77M | 4.38M | 64.73K | +3.79% |
| Mar 31, 2025 | BALYASNY ASSET MANAGEMENT L.P. | 1.3% | 1.31M | 3.22M | 1.31M | +100.00% |
| Mar 31, 2025 | ALYESKA INVESTMENT GROUP, L.P. | 0.61% | 615.88K | 1.52M | -900K | -59.37% |
| Mar 31, 2025 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 0.54% | 544.58K | 1.35M | -69.9K | -11.38% |
| Mar 31, 2025 | WELLINGTON MANAGEMENT GROUP LLP | 0.18% | 179.15K | 442.5K | -1.39K | -0.77% |
| Mar 31, 2025 | CITADEL ADVISORS LLC | 0.18% | 176.44K | 435.8K | -4.04M | -95.81% |
| Mar 31, 2025 | STONEPINE CAPITAL MANAGEMENT, LLC | 0.17% | 167.58K | 413.92K | 34.71K | +26.12% |
| Mar 31, 2025 | MILLENNIUM MANAGEMENT LLC | 0.15% | 149.3K | 368.77K | -4.57M | -96.83% |
| Mar 31, 2025 | FRANKLIN RESOURCES INC | 0.13% | 127.02K | 313.75K | 36.47K | +40.27% |
| Mar 31, 2025 | AMERICAN CENTURY COMPANIES INC | 0.09% | 91.39K | 225.73K | 12.52K | +15.88% |
| Mar 31, 2025 | ALLIANCEBERNSTEIN L.P. | 0.07% | 73.67K | 181.97K | 0 | 0 |
| Mar 31, 2025 | HGC INVESTMENT MANAGEMENT INC. | 0.07% | 70.43K | 173.95K | 70.43K | +100.00% |
| Mar 31, 2025 | DEUTSCHE BANK AG\ | 0.06% | 61.54K | 152K | -8.46K | -12.09% |
| Mar 31, 2025 | BLAIR WILLIAM & CO/IL | 0.14% | 138.6K | 342.33K | 0 | 0 |
| Mar 31, 2025 | SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | 0.27% | 273.41K | 675.33K | 35.95K | +15.14% |
| Mar 31, 2025 | NUVEEN, LLC | 0.2% | 202.24K | 499.53K | 202.24K | +100.00% |
| Mar 31, 2025 | AQR CAPITAL MANAGEMENT LLC | 0.19% | 193.32K | 477.51K | 193.32K | +100.00% |
| Mar 31, 2025 | BANK OF NEW YORK MELLON CORP | 0.17% | 173.28K | 428K | -3.62K | -2.05% |
| Mar 31, 2025 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 0.14% | 140.9K | 348.02K | 140.9K | +100.00% |
| Mar 31, 2025 | MONACO ASSET MANAGEMENT SAM | 0.14% | 139.6K | 344.81K | 139.6K | +100.00% |
| Mar 31, 2025 | UBS GROUP AG | 0.1% | 103.53K | 255.71K | -83.48K | -44.64% |
| Mar 31, 2025 | XTX TOPCO LTD | 0.1% | 103.05K | 254.53K | 92.68K | +893.80% |
| Mar 31, 2025 | RHUMBLINE ADVISERS | 0.1% | 102.17K | 252.37K | -6.07K | -5.61% |
| Mar 31, 2025 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0.09% | 90.67K | 223.95K | 55.85K | +160.36% |
| Mar 31, 2025 | BARCLAYS PLC | 0.08% | 82.87K | 204.69K | -33.77K | -28.95% |
| Mar 31, 2025 | ALPS ADVISORS INC | 0.07% | 74.64K | 184.36K | -6.49K | -8.00% |
| Mar 31, 2025 | AYURMAYA CAPITAL MANAGEMENT COMPANY, LP | 9.27% | 9.33M | 23.06M | 0 | 0 |
| Mar 31, 2025 | T. ROWE PRICE INVESTMENT MANAGEMENT, INC. | 4.62% | 4.65M | 11.49M | -8.22M | -63.88% |
| Mar 31, 2025 | VANGUARD GROUP INC | 4.05% | 4.08M | 10.08M | -304 | -0.01% |
| Mar 31, 2025 | TYBOURNE CAPITAL MANAGEMENT (HK) LTD | 2.89% | 2.91M | 7.18M | 0 | 0 |
| Mar 31, 2025 | RENAISSANCE TECHNOLOGIES LLC | 0.6% | 599.8K | 1.48M | 132.88K | +28.46% |
| Mar 31, 2025 | NORTHERN TRUST CORP | 0.59% | 598.15K | 1.48M | -31.9K | -5.06% |
| Mar 31, 2025 | JPMORGAN CHASE & CO | 0.59% | 590.85K | 1.46M | -27.28K | -4.41% |
| Mar 31, 2025 | CANTOR FITZGERALD, L. P. | 0.58% | 588.66K | 1.45M | 588.66K | +100.00% |
| Mar 31, 2025 | GENERAL ATLANTIC, L.P. | 2.68% | 2.7M | 6.66M | 0 | 0 |
| Mar 31, 2025 | SAMSARA BIOCAPITAL, LLC | 2.54% | 2.52M | 6.23M | 0 | 0 |
| Mar 31, 2025 | PALO ALTO INVESTORS LP | 1.81% | 1.79M | 4.43M | 0 | 0 |
| Mar 31, 2025 | TANG CAPITAL MANAGEMENT LLC | 9.75% | 9.82M | 24.25M | 9.82M | +100.00% |
| Mar 31, 2025 | BLACKROCK, INC. | 5.77% | 5.81M | 14.34M | -215.77K | -3.58% |
| Mar 31, 2025 | VENBIO PARTNERS LLC | 3.83% | 3.81M | 9.4M | 0 | 0 |
| Mar 31, 2025 | VELAN CAPITAL INVESTMENT MANAGEMENT LP | 3.39% | 3.37M | 8.32M | 3.37M | +100.00% |
Among the SLRN insiders holding of 7.15% of the stake in company, WESTLAKE BIOPARTNERS FUND II, L.P., 10 percent owner, holds the largest shares of 9.79M. LIN SHAO-LEE, Chief Executive Officer, is the second largest SLRN insider with ownership of 1.6M shares. KIM MINA, Chief Executive Officer, stands third with possession of 671.75K shares of that stake.
| Insiders | Designation | Shares Held |
|---|---|---|
| WESTLAKE BIOPARTNERS FUND II, L.P. | 10 percent owner | 9.79M |
| LIN SHAO-LEE | Chief Executive Officer | 1.6M |
| KIM MINA | Chief Executive Officer | 671.75K |
| MPOFU SHEPHARD | Chief Medical Officer | 121.79K |
| MURUGAN AMAR | Chief Legal Officer | 121.59K |
| GOSEBRUCH HENRY O | director | 50K |
| SVORONOS DAWN | director | 15K |
| BECKER DANIEL J. | director | 3K |
| Date | Insider | Type | Cost | Shares | Value ($) | Shares Total |
|---|---|---|---|---|---|---|
| Mar 17, 2025 | KIM MINA | SALE | 2.74 | 17.99K | 49.35K | 671.75K |
| Mar 17, 2025 | MURUGAN AMAR | SALE | 2.74 | 3.91K | 10.74K | 121.59K |
| Mar 17, 2025 | MPOFU SHEPHARD | SALE | 2.74 | 3.21K | 8.81K | 121.79K |
| Jul 17, 2024 | BECKER DANIEL J. | SALE | 6.86 | 1 | 6.86 | 3K |
| Jan 02, 2024 | LIN SHAO-LEE | SALE | 7.41 | 10.69K | 79.19K | 1.6M |
| May 09, 2023 | WESTLAKE BIOPARTNERS FUND II, L.P. | PURCHASE | 18.00 | 1.25M | 22.5M | 9.79M |
| May 09, 2023 | SVORONOS DAWN | PURCHASE | 18.00 | 15K | 270K | 15K |
| May 09, 2023 | GOSEBRUCH HENRY O | PURCHASE | 18.00 | 50K | 900K | 50K |
| May 09, 2023 | BECKER DANIEL J. | PURCHASE | 18.00 | 3K | 54K | 3K |