How many institutions own QURE stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own QURE shares is 186, representing 96.91% of the company's common stock.

Who are the major shareholders selling uniQure N.V. stock?

BALYASNY ASSET MANAGEMENT L.P., in the last quarter, reduced its stake in QURE by -37.94% restricting it's holding to 333.24 thousand shares of worth nearly $19.45M. CAPTION MANAGEMENT, LLC also lessened -74.52% of the QURE shares from its portfolio, reducing its holding to 381 thousand shares of worth $22.24M. BNP PARIBAS ARBITRAGE, SNC also shunned QURE shares holding by -23.44% last quarter which brought its holding to 385.61 thousand shares worth $22.51M.

Investors who are buying QURE stock?

As per its latest 13F filing, BANK OF AMERICA CORP /DE/ increased its stake in QURE by 108.12% in the last quarter. The institutional holder raised its holding to 295.13 thousand shares having worth more than $17.23M. CHARLES SCHWAB INVESTMENT MANAGEMENT INC also added 22.11% more shares of QURE to its portfolio, raising its holding to 357.69 thousand shares of worth $20.88M. DARWIN GLOBAL MANAGEMENT, LTD. also increased its QURE shares holding by 100% which brought its holding to 400 thousand shares worth $23.76M.

QURE's major insiders: who are they?

The insider with the most stakes in QURE is Kapusta Matthew C , CEO, Managing Director at the company. Additionally, QURE stock is highly held by Chief Financial Officer KLEMT CHRISTIAN and President, R&D Dolmetsch Ricardo among others.

Did an insider recently sell QURE stock?

Company executives, directors, and other insiders own 6.07% percent of uniQure N.V.'s stock. Within the last six months, there have been 6 transaction(s) in which QURE insiders have sold stock, totaling 112.87K shares. Insiders that have sold shares include GUT ROBERT, KAYE JACK, and KLEMT CHRISTIAN.

Which insider recently purchased QURE stock?

There have been 0 transaction(s) during the past 6-months in which uniQure N.V. insiders have bought stock, totalling 0 shares

How much of QURE does insiders own?

Around 1.3M uniQure N.V. shares are held by insiders, which represents about 6.07% of QURE stock.

Who is the insider with the largest stake?

QURE CEO, Managing Director, Kapusta Matthew C holds the largest portfolio of the company's shares. QURE shares owned by Kapusta total nearly 651.45 thousand.

Which institution holds the most shares in QURE?

BANK OF AMERICA CORP /DE/ is the largest institutional owner in QURE which holds 295.13 thousand shares worth $17.23M or 0.54% of the total QURE shares outstanding followed by BALYASNY ASSET MANAGEMENT L.P. with ownership of 333.24 thousand shares representing 0.57% of the QURE ownership. CHARLES SCHWAB INVESTMENT MANAGEMENT INC is the third largest stakeholder with 357.69 thousand shares or 0.61% of the ownership worth more than $20.88M.

Is uniQure N.V. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the QURE is concerned, it is a stock which is optionable.

Is there a short position on QURE's shares?

Number of QURE shares short is 9.06M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding QURE shares are there?

As of today, 54.87M shares of QURE are outstanding.

Is there many float in QURE stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, QURE has 38.74M shares in float.

QURE short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for QURE is 8.42.

uniQure NV (QURE) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares16.51

Short Percent Of Float16.73

Shares Outstanding54.87M

Shares Float38.74M

Shares Short9.06M

Short Ratio8.42

16.73%

Short % of Float

16.51%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

6.07% Percentage of Shares held by All Insiders

96.91% Percentage of Shares held by All Institutions

103.18% Percentage of Float held by Institutions

186

Number of Institutions Holding Shares

Institutional Ownership

About 96.91% of QURE shares are held by financial institutions. BANK OF AMERICA CORP /DE/ is the top corporate investor, holding 295.13K shares valued at $17.23M. A 0.54% stake in uniQure N.V. is owned by the company. BALYASNY ASSET MANAGEMENT L.P. owns 333.24K shares valued at $19.45M, which translates its holding of 0.57% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.54%	295.13K	17.23M	153.32K	+108.12%
Sep 30, 2025	BALYASNY ASSET MANAGEMENT L.P.	0.57%	333.24K	19.45M	-203.73K	-37.94%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.61%	357.69K	20.88M	64.75K	+22.11%
Sep 30, 2025	CAPTION MANAGEMENT, LLC	0.65%	381K	22.24M	-1.11M	-74.52%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.66%	385.61K	22.51M	-118.06K	-23.44%
Sep 30, 2025	DARWIN GLOBAL MANAGEMENT, LTD.	0.68%	400K	23.76M	400K	+100.00%
Sep 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.56%	913.18K	53.3M	913.18K	+100.00%
Sep 30, 2025	DIAMOND HILL CAPITAL MANAGEMENT INC	0.06%	33.33K	1.95M	-49.32K	-59.67%
Sep 30, 2025	LEGAL & GENERAL GROUP PLC	0.07%	35.62K	2.08M	0	0
Sep 30, 2025	PARKMAN HEALTHCARE PARTNERS LLC	0.59%	345.36K	20.16M	-98.07K	-22.12%
Sep 30, 2025	MONACO ASSET MANAGEMENT SAM	0.07%	39.91K	2.33M	-30.09K	-42.98%
Sep 30, 2025	MONASHEE INVESTMENT MANAGEMENT LLC	0.07%	40K	2.33M	40K	+100.00%
Sep 30, 2025	WINTON GROUP LTD	0.07%	40.98K	2.39M	40.98K	+100.00%
Sep 30, 2025	LPL FINANCIAL LLC	0.08%	46.11K	2.69M	46.11K	+100.00%
Sep 30, 2025	CI INVESTMENTS INC.	0.09%	47.44K	2.77M	47.44K	+100.00%
Sep 30, 2025	HENNION & WALSH ASSET MANAGEMENT, INC.	0.09%	51.61K	3.01M	21.24K	+69.95%
Sep 30, 2025	HEADLANDS TECHNOLOGIES LLC	0.1%	57.41K	3.35M	14.96K	+35.26%
Sep 30, 2025	STIFEL FINANCIAL CORP	0.11%	58.28K	3.4M	-8.71K	-13.00%
Sep 30, 2025	PATIENT SQUARE CAPITAL LP	0.14%	75K	4.38M	75K	+100.00%
Sep 30, 2025	SWISS NATIONAL BANK	0.14%	76.3K	4.45M	-1.2K	-1.55%
Sep 30, 2025	BIRCHVIEW CAPITAL, LP	0.14%	78.73K	4.6M	-19.97K	-20.23%
Sep 30, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.15%	82.86K	4.84M	14.05K	+20.42%
Sep 30, 2025	SANDERS MORRIS HARRIS LLC	0.16%	87.05K	5.08M	87.05K	+100.00%
Sep 30, 2025	ATIKA CAPITAL MANAGEMENT LLC	0.16%	90K	5.25M	90K	+100.00%
Sep 30, 2025	JEFFERIES FINANCIAL GROUP INC.	0.17%	90.54K	5.28M	-2.01M	-95.68%
Sep 30, 2025	TD ASSET MANAGEMENT INC	0.17%	95.14K	5.55M	95.14K	+100.00%
Sep 30, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.19%	102.12K	5.96M	34.86K	+51.83%
Sep 30, 2025	QUINN OPPORTUNITY PARTNERS LLC	0.2%	107.6K	6.28M	107.6K	+100.00%
Sep 30, 2025	MARSHALL WACE, LLP	0.2%	108.21K	6.32M	-114.77K	-51.47%
Sep 30, 2025	VOSS CAPITAL, LLC	0.23%	125K	1.74M	0	0
Sep 30, 2025	ROSALIND ADVISORS, INC.	0.23%	125K	7.3M	125K	+100.00%
Sep 30, 2025	GROUP ONE TRADING, L.P.	0.26%	140.23K	8.19B	76.55K	+120.20%
Sep 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0.27%	149.85K	8.75M	43.36K	+40.72%
Sep 30, 2025	LORD, ABBETT & CO. LLC	0.32%	176.03K	10.28M	176.03K	+100.00%
Sep 30, 2025	TWO SIGMA INVESTMENTS, LP	1.53%	897.54K	52.39M	-43.42K	-4.61%
Sep 30, 2025	PRIVIUM FUND MANAGEMENT B.V.	0.66%	386K	22.53M	-61.49K	-13.74%
Sep 30, 2025	BARCLAYS PLC	0.17%	93.2K	5.44M	-68.7K	-42.43%
Sep 30, 2025	CENTIVA CAPITAL, LP	0.43%	233.6K	13.64M	213.6K	+1,068.00%
Sep 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.46%	254.08K	14.83M	148.14K	+139.84%
Sep 30, 2025	CATALIO CAPITAL MANAGEMENT, LP	0.52%	282.94K	16.52M	-134.5K	-32.22%
Sep 30, 2025	683 CAPITAL MANAGEMENT, LLC	1.83%	1.07M	62.46M	-215K	-16.73%
Sep 30, 2025	MORGAN STANLEY	0.55%	321.5K	18.77M	-586.78K	-64.60%
Sep 30, 2025	TWO SIGMA ADVISERS, LP	0.7%	409.5K	23.9M	-250.2K	-37.93%
Sep 30, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.78%	455K	26.56M	252.44K	+124.62%
Sep 30, 2025	ORBIMED ADVISORS LLC	0.78%	458.5K	26.76M	458.5K	+100.00%
Sep 30, 2025	STEMPOINT CAPITAL LP	0.89%	522.16K	30.48M	-50.46K	-8.81%
Sep 30, 2025	FARALLON CAPITAL MANAGEMENT LLC	0.97%	565K	32.98M	551K	+3,935.71%
Sep 30, 2025	UBS GROUP AG	0.37%	204.99K	11.97M	-58.68K	-22.25%
Sep 30, 2025	MACQUARIE GROUP LTD	0.47%	258.21K	15.07M	-447.96K	-63.43%
Sep 30, 2025	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	1.03%	600K	35.02M	-750K	-55.56%
Sep 30, 2025	CITADEL ADVISORS LLC	0.73%	429.71K	25.08M	-126.16K	-22.70%
Sep 30, 2025	ARTIA GLOBAL PARTNERS LP	1.13%	658.84K	38.46M	658.84K	+100.00%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.23%	721.65K	42.14M	118.44K	+19.64%
Sep 30, 2025	BOXER CAPITAL MANAGEMENT, LLC	1.37%	800K	46.7M	-99.5K	-11.06%
Sep 30, 2025	EVERSEPT PARTNERS, LP	1.5%	877.37K	51.21M	877.37K	+100.00%
Sep 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	1.51%	884K	51.6M	341.7K	+63.01%
Sep 30, 2025	JENNISON ASSOCIATES LLC	1.71%	999.48K	58.34M	859.42K	+613.61%
Sep 30, 2025	NANTAHALA CAPITAL MANAGEMENT, LLC	1.72%	1.01M	58.81M	-1.04M	-50.90%
Sep 30, 2025	ECOR1 CAPITAL, LLC	6.82%	3.99M	232.84M	0	0
Sep 30, 2025	RTW INVESTMENTS, LP	7.56%	4.42M	258.29M	-733.26K	-14.22%
Sep 30, 2025	AVORO CAPITAL ADVISORS LLC	7.6%	4.44M	259.42M	819.44K	+22.61%
Sep 30, 2025	DEEP TRACK CAPITAL, LP	0.83%	483.09K	28.2M	483.09K	+100.00%
Sep 30, 2025	JANE STREET GROUP, LLC	0.86%	505.2K	29.49M	478.1K	+1,764.21%
Sep 30, 2025	NATIONALE-NEDERLANDEN POWSZECHNE TOWARZYSTWO EMERYTALNE S.A.	0.89%	521.68K	30.45M	521.68K	+100.00%
Sep 30, 2025	VANGUARD GROUP INC	1.92%	1.13M	65.67M	152.42K	+15.67%
Sep 30, 2025	JPMORGAN CHASE & CO	2.1%	1.15M	67.09M	-658.33K	-36.42%
Sep 30, 2025	FRED ALGER MANAGEMENT, LLC	2.21%	1.29M	75.32M	1.29M	+100.00%
Sep 30, 2025	STATE STREET CORP	2.47%	1.44M	84.29M	301.2K	+26.36%
Sep 30, 2025	SIREN, L.L.C.	0.5%	275.2K	16.06M	275.2K	+100.00%
Sep 30, 2025	FMR LLC	10.36%	6.06M	353.7M	4.88M	+411.63%
Sep 30, 2025	DLD ASSET MANAGEMENT, LP	0.11%	60.4K	3.52M	60.4K	+100.00%
Sep 30, 2025	SEI INVESTMENTS CO	0.12%	67.27K	3.93M	67.27K	+100.00%
Sep 30, 2025	HUDSON BAY CAPITAL MANAGEMENT LP	0.12%	67.7K	3.95M	67.7K	+100.00%
Sep 30, 2025	DIADEMA PARTNERS LP	0.51%	300K	17.51M	300K	+100.00%
Sep 30, 2025	LOGOS GLOBAL MANAGEMENT LP	0.51%	300K	17.51M	300K	+100.00%
Sep 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.51%	300K	17.51M	165K	+122.22%
Sep 30, 2025	SOFINNOVA INVESTMENTS, INC.	0.51%	300K	17.51M	300K	+100.00%
Sep 30, 2025	SIMPLEX TRADING, LLC	0.12%	68K	3.97M	3.74K	+5.81%
Sep 30, 2025	BLACKROCK, INC.	2.47%	1.45M	84.41M	112.44K	+8.43%
Sep 30, 2025	FRANKLIN RESOURCES INC	3.4%	1.99M	116.07M	383.07K	+23.86%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	1.13%	662.21K	38.65M	305.75K	+85.77%
Sep 30, 2025	ABRDN PLC	5.02%	2.94M	171.59M	189.03K	+6.87%
Jun 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.92%	503.67K	7.02M	22.22K	+4.62%
Jun 30, 2025	PARKMAN HEALTHCARE PARTNERS LLC	0.81%	443.42K	6.18M	239.59K	+117.54%
Jun 30, 2025	ROYAL BANK OF CANADA	0.71%	391.61K	5.46M	342.28K	+693.85%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.65%	356.46K	4.97M	96.83K	+37.29%
Jun 30, 2025	BANK OF NEW YORK MELLON CORP	0.64%	348.33K	4.86M	348.33K	+100.00%
Jun 30, 2025	FMR LLC	2.16%	1.18M	16.51M	-16.58K	-1.38%
Jun 30, 2025	MORGAN STANLEY	1.66%	908.28K	12.66M	304.77K	+50.50%
Jun 30, 2025	ECOR1 CAPITAL, LLC	7.28%	3.99M	55.61M	0	0
Jun 30, 2025	SCHONFELD STRATEGIC ADVISORS LLC	0.25%	134.95K	1.88M	92.8K	+220.18%
Jun 30, 2025	VOSS CAPITAL, LLC	0.23%	125K	1.74M	125K	+100.00%
Jun 30, 2025	J. GOLDMAN & CO LP	0.22%	121.6K	1.7M	67.6K	+125.19%
Jun 30, 2025	IKARIAN CAPITAL, LLC	0.22%	119.99K	1.67M	119.99K	+100.00%
Jun 30, 2025	BIRCHVIEW CAPITAL, LP	0.18%	98.7K	1.38M	10K	+11.27%
Jun 30, 2025	VERITION FUND MANAGEMENT LLC	0.17%	92.59K	1.29M	-3.94K	-4.08%
Jun 30, 2025	RTW INVESTMENTS, LP	9.41%	5.16M	71.91M	892.8K	+20.93%
Jun 30, 2025	VESTAL POINT CAPITAL, LP	6.75%	3.7M	51.58M	-1.09M	-22.80%
Jun 30, 2025	Y-INTERCEPT (HONG KONG) LTD	0.11%	62.54K	871.78K	62.54K	+100.00%
Jun 30, 2025	SECTORAL ASSET MANAGEMENT INC	0.1%	55.45K	772.97K	-2.1K	-3.65%
Jun 30, 2025	CENTIVA CAPITAL, LP	0.09%	50K	697K	50K	+100.00%
Jun 30, 2025	HEADLANDS TECHNOLOGIES LLC	0.08%	42.44K	591.67K	31.95K	+304.38%
Jun 30, 2025	SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC	0.07%	38.53K	537.16K	0	0
Jun 30, 2025	AQUATIC CAPITAL MANAGEMENT LLC	0.06%	35.26K	491.55K	24.67K	+232.97%
Jun 30, 2025	HENNION & WALSH ASSET MANAGEMENT, INC.	0.06%	30.37K	423.34K	30.37K	+100.00%
Jun 30, 2025	HRT FINANCIAL LP	0.05%	28.42K	396K	28.42K	+100.00%
Jun 30, 2025	NANTAHALA CAPITAL MANAGEMENT, LLC	3.74%	2.05M	28.6M	-704.11K	-25.55%
Jun 30, 2025	CATALIO CAPITAL MANAGEMENT, LP	0.76%	417.44K	5.82M	-412.88K	-49.73%
Jun 30, 2025	BOXER CAPITAL MANAGEMENT, LLC	1.64%	899.5K	12.54M	149.5K	+19.93%
Jun 30, 2025	JPMORGAN CHASE & CO	3.3%	1.81M	25.2M	1.49M	+471.69%
Jun 30, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.51%	279K	3.89M	182.8K	+190.02%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.53%	292.93K	4.08M	12.93K	+4.62%
Jun 30, 2025		0.76%	417.44K	5.82M	-412.88K	-49.73%
Jun 30, 2025	MACQUARIE GROUP LTD	1.29%	706.17K	9.84M	0	0
Jun 30, 2025	CITADEL ADVISORS LLC	1.01%	555.87K	7.75M	-229.46K	-29.22%
Jun 30, 2025	STEMPOINT CAPITAL LP	1.04%	572.62K	7.98M	-158.42K	-21.67%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.1%	603.21K	8.41M	-7.76K	-1.27%
Jun 30, 2025	TWO SIGMA ADVISERS, LP	1.2%	659.7K	9.2M	-8.79K	-1.32%
Jun 30, 2025	SCHRODER INVESTMENT MANAGEMENT GROUP	1.26%	693.28K	9.66M	-496.84K	-41.75%
Jun 30, 2025	TWO SIGMA INVESTMENTS, LP	1.72%	940.96K	13.12M	24.46K	+2.67%
Jun 30, 2025	VANGUARD GROUP INC	1.77%	972.69K	13.56M	27.23K	+2.88%
Jun 30, 2025	STATE STREET CORP	2.09%	1.14M	15.93M	-86.78K	-7.06%
Jun 30, 2025	683 CAPITAL MANAGEMENT, LLC	2.34%	1.29M	17.91M	-265K	-17.10%
Jun 30, 2025	BLACKROCK, INC.	2.43%	1.33M	18.59M	-103.32K	-7.19%
Jun 30, 2025	AMERIPRISE FINANCIAL INC	1.39%	761.95K	10.62M	212.22K	+38.60%
Jun 30, 2025	FRANKLIN RESOURCES INC	2.93%	1.61M	22.38M	-382.17K	-19.23%
Jun 30, 2025	JEFFERIES FINANCIAL GROUP INC.	3.82%	2.1M	29.22M	2.1M	+100.00%
Jun 30, 2025	ABRDN PLC	5.02%	2.75M	38.34M	535.16K	+24.15%
Jun 30, 2025	AVORO CAPITAL ADVISORS LLC	6.61%	3.63M	50.53M	1.45M	+66.67%
Jun 30, 2025	PFM HEALTH SCIENCES, LP	0.32%	174.33K	2.43M	-425.64K	-70.94%
Jun 30, 2025	MOORE CAPITAL MANAGEMENT, LP	0.32%	175K	2.44M	25K	+16.67%
Jun 30, 2025	WOODLINE PARTNERS LP	0.32%	175.81K	2.45M	0	0
Jun 30, 2025	SQUAREPOINT OPS LLC	0.32%	176K	2.45M	-2.33K	-1.31%
Jun 30, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.37%	202.57K	2.82M	-835	-0.41%
Jun 30, 2025	AVIDITY PARTNERS MANAGEMENT LP	0.38%	207K	2.89M	-129.2K	-38.43%
Jun 30, 2025	MARSHALL WACE, LLP	0.41%	222.98K	3.11M	163.75K	+276.46%
Jun 30, 2025	UBS GROUP AG	0.48%	263.67K	3.68M	36.77K	+16.21%
Jun 30, 2025	CAPTION MANAGEMENT, LLC	0.32%	176.91K	2.47M	156.55K	+768.96%
Jun 30, 2025	UBS OCONNOR LLC	0.15%	80K	124K	15K	+23.08%
Jun 30, 2025	DIAMOND HILL CAPITAL MANAGEMENT INC	0.15%	82.65K	1.15M	0	0
Jun 30, 2025	SHAY CAPITAL LLC	0.18%	99.38K	1.39M	17.53K	+21.42%
Jun 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.18%	100K	1.39M	100K	+100.00%
Jun 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.19%	105.94K	1.48M	-24.14K	-18.56%
Jun 30, 2025	PEAK6 LLC	0.21%	112.9K	1.57M	92.1K	+442.79%
Jun 30, 2025	JENNISON ASSOCIATES LLC	0.26%	140.06K	1.95M	140.06K	+100.00%
Jun 30, 2025	HUDSON BAY CAPITAL MANAGEMENT LP	0.27%	148.18K	2.07M	-3.52K	-2.32%
Jun 30, 2025	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	2.46%	1.35M	18.82M	100K	+8.00%
Jun 30, 2025	SOFINNOVA INVESTMENTS, INC.	2.84%	1.56M	21.72M	1.01M	+185.53%
Jun 30, 2025	MONACO ASSET MANAGEMENT SAM	0.13%	70K	975.8K	-5K	-6.67%
Jun 30, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.13%	68.81K	959.17K	-13.78K	-16.69%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.99%	542.3K	7.56M	385.6K	+246.08%
Jun 30, 2025	BALYASNY ASSET MANAGEMENT L.P.	0.98%	536.97K	7.49M	512.04K	+2,054.08%
Jun 30, 2025	PALE FIRE CAPITAL SE	0.97%	529.8K	7.39M	67.44K	+14.59%
Jun 30, 2025	PRIVIUM FUND MANAGEMENT B.V.	0.82%	447.49K	6.26M	-131.65K	-22.73%
Mar 31, 2025	STEMPOINT CAPITAL LP	1.38%	731.04K	7.75M	641.04K	+712.27%
Mar 31, 2025	VESTAL POINT CAPITAL, LP	9.02%	4.79M	50.8M	1.77M	+58.43%
Mar 31, 2025	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	2.35%	1.25M	13.25M	150K	+13.64%
Mar 31, 2025	TWO SIGMA INVESTMENTS, LP	1.73%	916.5K	9.71M	37.62K	+4.28%
Mar 31, 2025		1.41%	750K	7.95M	0	0
Mar 31, 2025	CITADEL ADVISORS LLC	1.48%	785.32K	8.32M	773.31K	+6,441.06%
Mar 31, 2025	CUBIST SYSTEMATIC STRATEGIES, LLC	0.46%	241.68K	2.56M	241.68K	+100.00%
Mar 31, 2025	PALE FIRE CAPITAL SE	0.87%	462.36K	4.9M	-118.35K	-20.38%
Mar 31, 2025	ACADIAN ASSET MANAGEMENT LLC	0.47%	250.1K	2.65M	-7.72K	-2.99%
Mar 31, 2025	ECOR1 CAPITAL, LLC	7.51%	3.99M	42.28M	588.97K	+17.32%
Mar 31, 2025	NANTAHALA CAPITAL MANAGEMENT, LLC	5.19%	2.76M	29.21M	302.6K	+12.33%
Mar 31, 2025	AVORO CAPITAL ADVISORS LLC	4.1%	2.18M	23.06M	0	0
Mar 31, 2025	BLACKROCK, INC.	2.71%	1.44M	15.23M	21.42K	+1.51%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.15%	610.97K	6.48M	90.42K	+17.37%
Mar 31, 2025	MORGAN STANLEY	1.14%	603.52K	6.4M	-93.81K	-13.45%
Mar 31, 2025	PRIVIUM FUND MANAGEMENT B.V.	1.09%	579.14K	6.14M	-163.02K	-21.97%
Mar 31, 2025	AMERIPRISE FINANCIAL INC	1.04%	549.73K	5.83M	17.9K	+3.37%
Mar 31, 2025	SOFINNOVA INVESTMENTS, INC.	1.03%	545.77K	5.79M	545.77K	+100.00%
Mar 31, 2025	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.94%	500.98K	5.31M	323.8K	+182.75%
Mar 31, 2025	LORD, ABBETT & CO. LLC	0.75%	400.79K	4.25M	86.37K	+27.47%
Mar 31, 2025	AVIDITY PARTNERS MANAGEMENT LP	0.63%	336.2K	3.56M	114.2K	+51.44%
Mar 31, 2025	ASSENAGON ASSET MANAGEMENT S.A.	0.63%	334.89K	3.55M	261.32K	+355.20%
Mar 31, 2025	WALLEYE CAPITAL LLC	0.5%	266.73K	2.83M	136.3K	+104.51%
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	0.5%	265.67K	2.82M	-198.87K	-42.81%
Mar 31, 2025	PARKMAN HEALTHCARE PARTNERS LLC	0.38%	203.83K	2.16M	-71.17K	-25.88%
Mar 31, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.38%	203.4K	2.16M	103.4K	+103.40%
Mar 31, 2025	RTW INVESTMENTS, LP	8.03%	4.27M	45.21M	3.36M	+372.04%
Mar 31, 2025	ABRDN PLC	4.17%	2.22M	23.48M	706.22K	+46.79%
Mar 31, 2025	AFFINITY ASSET ADVISORS, LLC	0.75%	400K	4.24M	400K	+100.00%
Mar 31, 2025	UBS GROUP AG	0.43%	226.9K	2.41M	83.07K	+57.76%
Mar 31, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.38%	200K	2.12M	200K	+100.00%
Mar 31, 2025	MACQUARIE GROUP LTD	1.33%	706.17K	7.49B	0	0
Mar 31, 2025	TWO SIGMA ADVISERS, LP	1.26%	668.49K	7.09M	-88.41K	-11.68%
Mar 31, 2025	PFM HEALTH SCIENCES, LP	1.13%	599.97K	6.36M	316.81K	+111.88%
Mar 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.91%	481.45K	5.1M	13.09K	+2.80%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0.72%	380.85K	4.04M	311.79K	+451.45%
Mar 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.7%	372K	3.94M	-11.7K	-3.05%
Mar 31, 2025	JPMORGAN CHASE & CO	0.6%	316.2K	3.35M	-137.59K	-30.32%
Mar 31, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0.57%	303.63K	3.22M	303.63K	+100.00%
Mar 31, 2025	IKARIAN CAPITAL, LLC	0.56%	300K	3.18M	300K	+100.00%
Mar 31, 2025	FRANKLIN RESOURCES INC	3.74%	1.99M	21.07M	0	0
Mar 31, 2025	683 CAPITAL MANAGEMENT, LLC	2.92%	1.55M	16.43M	25K	+1.64%
Mar 31, 2025	INVESCO LTD.	0.91%	485.31K	5.14M	-128.3K	-20.91%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.53%	280K	2.97M	10.02K	+3.71%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.49%	259.64K	2.75M	180.31K	+227.31%
Mar 31, 2025	STATE STREET CORP	2.32%	1.23M	13.03M	1.04M	+538.64%
Mar 31, 2025	FMR LLC	2.26%	1.2M	12.73M	234.29K	+24.24%
Mar 31, 2025	SCHRODER INVESTMENT MANAGEMENT GROUP	2.24%	1.19M	14.84M	356.05K	+42.69%
Mar 31, 2025	VANGUARD GROUP INC	1.78%	945.47K	10.02M	-161.14K	-14.56%
Mar 31, 2024	SIMPLEX TRADING, LLC	0.18%	84.59K	439K	62.99K	+291.62%
Mar 31, 2024	ACADIAN ASSET MANAGEMENT LLC	1.28%	613.49K	3.19M	350.29K	+133.09%
Mar 31, 2024	MACQUARIE GROUP LTD	1.48%	706.17K	3.67M	0	0
Mar 31, 2024	AMERIPRISE FINANCIAL INC	1.48%	709.44K	3.69M	-110.83K	-13.51%
Mar 31, 2024	BNP PARIBAS ARBITRAGE, SNC	1.54%	736.72K	3.83M	30.05K	+4.25%
Mar 31, 2024	D. E. SHAW & CO., INC.	1.78%	850.1K	4.42M	289.77K	+51.71%
Mar 31, 2024	STIFEL FINANCIAL CORP	0.05%	23.52K	122.28K	286	+1.23%
Mar 31, 2024	UBS GROUP AG	0.06%	26.71K	138.88K	-141.29K	-84.10%
Mar 31, 2024	RAYMOND JAMES & ASSOCIATES	0.06%	27.37K	142.31K	-24.86K	-47.60%
Mar 31, 2024	BALYASNY ASSET MANAGEMENT L.P.	0.06%	28.79K	149.71K	9.77K	+51.37%
Mar 31, 2024	FMR LLC	0.06%	28.81K	149.79K	-19.98K	-40.95%
Mar 31, 2024	BANK OF MONTREAL /CAN/	0.07%	32.4K	175.28K	10.6K	+48.62%
Mar 31, 2024	CI PRIVATE WEALTH, LLC	0.07%	32.6K	169.52K	32.6K	+100.00%
Mar 31, 2024	WORTH VENTURE PARTNERS, LLC	0.07%	34.3K	178.36K	34.3K	+100.00%
Mar 31, 2024	HARBOR CAPITAL ADVISORS, INC.	0.07%	34.87K	181K	3.98K	+12.90%
Mar 31, 2024	CLEAR HARBOR ASSET MANAGEMENT, LLC	0.07%	35.5K	184.6K	22.6K	+175.19%
Mar 31, 2024	HENRY JAMES INTERNATIONAL MANAGEMENT INC.	0.08%	39.52K	205.49K	-1.77K	-4.28%
Mar 31, 2024	CITIGROUP INC	0.08%	39.99K	207.94K	-703.92K	-94.62%
Mar 31, 2024	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.09%	40.65K	211.39K	23.97K	+143.67%
Mar 31, 2024	HRT FINANCIAL LP	0.09%	45.04K	234K	-11.85K	-20.83%
Mar 31, 2024	ALLIANZ ASSET MANAGEMENT GMBH	0.11%	50.64K	263.34K	0	0
Mar 31, 2024	COVESTOR LTD	0.11%	53.69K	279K	27.27K	+103.19%
Mar 31, 2024	AMERICAN CENTURY COMPANIES INC	0.12%	59.06K	307.1K	14.56K	+32.72%
Mar 31, 2024	Y-INTERCEPT (HONG KONG) LTD	0.12%	59.29K	308.32K	46.11K	+349.86%
Mar 31, 2024	PALE FIRE CAPITAL SE	0.14%	65.6K	341.12K	0	0
Mar 31, 2024	SANDERS MORRIS HARRIS LLC	0.14%	68.07K	353.96K	0	0
Mar 31, 2024	DIAMOND HILL CAPITAL MANAGEMENT INC	0.16%	76.63K	398.48K	22.45K	+41.42%
Mar 31, 2024	SIGMA PLANNING CORP	0.17%	82.66K	429.81K	53.91K	+187.55%
Mar 31, 2024	SCHRODER INVESTMENT MANAGEMENT GROUP	2.6%	1.24M	6.46M	0	0
Mar 31, 2024	NORTHERN TRUST CORP	0.18%	84.9K	441.5K	-2.23K	-2.56%
Mar 31, 2024	683 CAPITAL MANAGEMENT, LLC	4.13%	1.98M	10.27M	282K	+16.66%
Mar 31, 2024	VESTAL POINT CAPITAL, LP	9.88%	4.73M	24.57M	800K	+20.38%
Mar 31, 2024	JUMP FINANCIAL, LLC	0.21%	99.68K	518.32K	-9.21K	-8.46%
Mar 31, 2024	INVESCO LTD.	0.23%	108.6K	564.71K	72.8K	+203.35%
Mar 31, 2024	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.24%	116.71K	607K	116.71K	+100.00%
Mar 31, 2024	PDT PARTNERS, LLC	0.25%	121.87K	633.7K	21.66K	+21.62%
Mar 31, 2024	BANQUE PICTET & CIE SA	0.28%	132.18K	687.34K	-12.4K	-8.58%
Mar 31, 2024	TANG CAPITAL MANAGEMENT LLC	0.28%	133.92K	696.39K	-466.08K	-77.68%
Mar 31, 2024	MIRAE ASSET GLOBAL INVESTMENTS CO., LTD.	0.33%	157.31K	3.14M	66.96K	+74.11%
Mar 31, 2024	POINT72 ASSET MANAGEMENT, L.P.	0.39%	185.22K	963.17K	-746.06K	-80.11%
Mar 31, 2024	BOOTHBAY FUND MANAGEMENT, LLC	0.4%	192.81K	1M	156.08K	+424.82%
Mar 31, 2024	STATE STREET CORP	0.43%	203.8K	1.06M	-3.28M	-94.14%
Mar 31, 2024	JANE STREET GROUP, LLC	0.45%	215.67K	1.12M	110.47K	+105.00%
Mar 31, 2024	CARLSON CAPITAL L P	0.48%	227.4K	1.18M	32.4K	+16.62%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.49%	235.49K	1.22M	13.1K	+5.89%
Mar 31, 2024	TWO SIGMA INVESTMENTS, LP	0.49%	236.28K	1.23M	114.3K	+93.71%
Mar 31, 2024	NANTAHALA CAPITAL MANAGEMENT, LLC	0.51%	243K	1.26M	43K	+21.50%
Mar 31, 2024	RENAISSANCE TECHNOLOGIES LLC	0.52%	246.41K	1.28M	-18.1K	-6.84%
Mar 31, 2024	GROUP ONE TRADING, L.P.	0.53%	254.03K	1.32M	203.75K	+405.21%
Mar 31, 2024	PFM HEALTH SCIENCES, LP	0.57%	274.54K	1.43M	274.54K	+100.00%
Mar 31, 2024	TWO SIGMA ADVISERS, LP	0.61%	289.5K	1.51M	261.2K	+922.97%
Mar 31, 2024	ADAR1 CAPITAL MANAGEMENT, LLC	0.61%	292.85K	1.52M	292.85K	+100.00%
Mar 31, 2024	VERITION FUND MANAGEMENT LLC	0.65%	310.57K	1.61M	7.13K	+2.35%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.66%	314.46K	1.64M	39.59K	+14.40%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.76%	362.33K	1.88M	-333.01K	-47.89%
Mar 31, 2024	BRIDGER MANAGEMENT, LLC	0.76%	362.35K	1.88M	0	0
Mar 31, 2024	ABRDN PLC	0.84%	400.48K	2.08M	0	0
Mar 31, 2024	IKARIAN CAPITAL, LLC	0.98%	469.13K	2.44M	311.77K	+198.12%
Mar 31, 2024	MILLENNIUM MANAGEMENT LLC	0.99%	474.58K	2.47M	19.11K	+4.20%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	1.01%	481.3K	2.5M	318.7K	+196.00%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	1.04%	499.82K	2.6M	20.15K	+4.20%
Mar 31, 2024	J. GOLDMAN & CO LP	1.07%	510.51K	2.65M	510.51K	+100.00%
Mar 31, 2024	VANGUARD GROUP INC	2.24%	1.07M	5.58M	109.74K	+11.40%
Mar 31, 2024	MORGAN STANLEY	3.17%	1.52M	7.89M	-241.59K	-13.73%
Mar 31, 2024	BLACKROCK INC.	3.89%	1.86M	9.68M	23.99K	+1.31%
Mar 31, 2024	GHOST TREE CAPITAL, LLC	0.34%	165K	858K	0	0
Mar 31, 2024	ALPHACENTRIC ADVISORS LLC	0.96%	460K	2.39M	38.98K	+9.26%
Mar 31, 2024	HUDSON BAY CAPITAL MANAGEMENT LP	1.1%	525K	2.73M	100K	+23.53%
Mar 31, 2024	CITADEL ADVISORS LLC	1.15%	550.57K	2.86M	379.52K	+221.89%
Mar 31, 2024	PRIVIUM FUND MANAGEMENT B.V.	1.21%	578.92K	3.01M	134.77K	+30.34%
Mar 31, 2024	JPMORGAN CHASE & CO	2.03%	969.5K	5.04M	220.15K	+29.38%
Dec 31, 2023	AMERIPRISE FINANCIAL INC	1.72%	820.26K	5.55M	445.8K	+119.05%
Dec 31, 2023	POINT72 ASSET MANAGEMENT, L.P.	1.95%	931.29K	6.3M	890.31K	+2,172.81%
Dec 31, 2023	VANGUARD GROUP INC	2.02%	962.8K	6.52M	9.36K	+0.98%
Dec 31, 2023	SCHRODER INVESTMENT MANAGEMENT GROUP	2.6%	1.24M	8.4M	1.24M	+100.00%
Dec 31, 2023		2.77%	1.32M	8.97M	320.55K	+31.94%
Dec 31, 2023	ORBIMED ADVISORS LLC	2.82%	1.35M	9.13M	-716.56K	-34.71%
Dec 31, 2023	683 CAPITAL MANAGEMENT, LLC	3.54%	1.69M	11.46M	118K	+7.49%
Dec 31, 2023	MORGAN STANLEY	3.68%	1.76M	11.91M	-921.59K	-34.37%
Dec 31, 2023	BLACKROCK INC.	3.84%	1.84M	12.43M	105.48K	+6.09%
Dec 31, 2023	STATE STREET CORP	7.28%	3.48M	23.55M	28.59K	+0.83%
Dec 31, 2023	SCHONFELD STRATEGIC ADVISORS LLC	0.26%	124.55K	843.2K	-258.08K	-67.45%
Dec 31, 2023	WALLEYE CAPITAL LLC	0.29%	140.76K	952.91K	14.78K	+11.73%
Dec 31, 2023	BANQUE PICTET & CIE SA	0.3%	144.59K	978.84K	-16.04K	-9.99%
Dec 31, 2023	BARCLAYS PLC	0.31%	149.47K	1.01M	-840.09K	-84.90%
Dec 31, 2023	NOMURA HOLDINGS INC	0.31%	150K	1.02M	150K	+100.00%
Dec 31, 2023	IKARIAN CAPITAL, LLC	0.33%	157.37K	1.07M	0	0
Dec 31, 2023	GHOST TREE CAPITAL, LLC	0.35%	165K	1.12M	-50K	-23.26%
Dec 31, 2023	UBS GROUP AG	0.35%	168K	1.14M	81.53K	+94.29%
Dec 31, 2023	CITADEL ADVISORS LLC	0.36%	171.04K	1.16M	-370.87K	-68.44%
Dec 31, 2023	ALGERT GLOBAL LLC	0.39%	188.21K	1.27M	-226.04K	-54.57%
Dec 31, 2023	CARLSON CAPITAL L P	0.41%	195K	1.32M	-100	-0.05%
Dec 31, 2023	NANTAHALA CAPITAL MANAGEMENT, LLC	0.42%	200K	1.35M	52.3K	+35.41%
Dec 31, 2023	NORGES BANK	0.43%	207.1K	1.4M	207.1K	+100.00%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.47%	222.39K	1.51M	-18.62K	-7.73%
Dec 31, 2023	SILVERCREST ASSET MANAGEMENT GROUP LLC	0.49%	235.21K	1.59M	-18.46K	-7.28%
Dec 31, 2023	ACADIAN ASSET MANAGEMENT LLC	0.55%	263.2K	1.78M	263.2K	+100.00%
Dec 31, 2023	RENAISSANCE TECHNOLOGIES LLC	0.55%	264.51K	1.79M	-184.6K	-41.10%
Dec 31, 2023	CUBIST SYSTEMATIC STRATEGIES, LLC	0.57%	274.45K	1.86M	77.29K	+39.20%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.58%	274.87K	1.86M	-79.16K	-22.36%
Dec 31, 2023	SECTORAL ASSET MANAGEMENT INC	0.61%	292.59K	1.98M	292.59K	+100.00%
Dec 31, 2023	VONTOBEL HOLDING LTD.	0.62%	295.04K	2M	242.21K	+458.50%
Dec 31, 2023	VERITION FUND MANAGEMENT LLC	0.64%	303.44K	2.05M	-340.21K	-52.86%
Dec 31, 2023	BRIDGER MANAGEMENT, LLC	0.76%	362.35K	2.45M	350.34K	+2,917.31%
Dec 31, 2023	RAFFERTY ASSET MANAGEMENT, LLC	0.77%	368.78K	2.5M	-22.06K	-5.64%
Dec 31, 2023	ABRDN PLC	0.84%	400.48K	2.71M	400.48K	+100.00%
Dec 31, 2023	ALPHACENTRIC ADVISORS LLC	0.88%	421.03K	2.85M	29.53K	+7.54%
Dec 31, 2023	HUDSON BAY CAPITAL MANAGEMENT LP	0.89%	425K	2.88M	34.8K	+8.92%
Dec 31, 2023	CAPTION MANAGEMENT, LLC	0.92%	441K	2.99M	381K	+635.00%
Dec 31, 2023	PRIVIUM FUND MANAGEMENT B.V.	0.93%	444.15K	3.08M	162.54K	+57.72%
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	0.95%	455.47K	3.08M	75.71K	+19.94%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	1%	479.68K	3.25M	31.44K	+7.01%
Dec 31, 2023	D. E. SHAW & CO., INC.	1.17%	560.33K	3.79M	148.6K	+36.09%
Dec 31, 2023	TANG CAPITAL MANAGEMENT LLC	1.26%	600K	4.06M	-335.8K	-35.88%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	1.46%	695.35K	4.71M	233.53K	+50.57%
Dec 31, 2023	MACQUARIE GROUP LTD	1.48%	706.17K	4.78M	0	0
Dec 31, 2023	BNP PARIBAS ARBITRAGE, SNC	1.48%	706.67K	4.78M	448.32K	+173.53%
Dec 31, 2023	CITIGROUP INC	1.56%	743.91K	5.04M	-22.61K	-2.95%
Dec 31, 2023	JPMORGAN CHASE & CO	1.57%	749.35K	5.07M	156.43K	+26.38%

Insiders

Among the QURE insiders holding of 6.07% of the stake in company, KAPUSTA MATTHEW C, CEO, Managing Director, holds the largest shares of 651.45K. KLEMT CHRISTIAN, Chief Financial Officer, is the second largest QURE insider with ownership of 217.73K shares. DOLMETSCH RICARDO, President, R&D, stands third with possession of 163.4K shares of that stake.

Insiders	Designation	Shares Held
KAPUSTA MATTHEW C	CEO, Managing Director	651.45K
KLEMT CHRISTIAN	Chief Financial Officer	217.73K
DOLMETSCH RICARDO	President, R&D	163.4K
ABI-SAAB WALID	Chief Medical Officer	150.44K
CALOZ PIERRE	Chief Operating Officer	115.71K
POTTS JEANNETTE	Chief Legal Officer	115.07K
KUTA ALEXANDER EDWARD III	Executive VP, Operations	90.38K
GUT ROBERT	director	40.15K
BALACHANDRAN MADHAVAN	director	37.7K
SPRINGHORN JEREMY P.	director	37.69K
MEEK DAVID D.	director	34.19K
POST LEONARD E	director	29.94K
JACQUES RACHELLE SUZANNE	director	28.35K
KAYE JACK	director	20.44K
SOTEROPOULOS PAULA	director	20.2K
ASTLEY-SPARKE PHILIP	director	9.95K

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Nov 06, 2025	GUT ROBERT	SALE	27.30	15.59K	425.72K	40.15K
Nov 04, 2025	KAYE JACK	SALE	30.33	17.81K	540.18K	20.44K
Sep 26, 2025	KLEMT CHRISTIAN	SALE	55.00	15K	825K	217.73K
Sep 24, 2025	KLEMT CHRISTIAN	SALE	40.04	3K	120.12K	217.73K
Sep 24, 2025	KAPUSTA MATTHEW C	SALE	45.10	60K	2.71M	651.45K
Jun 27, 2025	ABI-SAAB WALID	SALE	13.92	1.47K	20.41K	150.44K
Jun 20, 2025	BALACHANDRAN MADHAVAN	SALE	14.45	2.11K	30.52K	37.7K
Jun 20, 2025	POST LEONARD E	SALE	14.45	2.11K	30.52K	29.94K
Jun 20, 2025	SPRINGHORN JEREMY P.	SALE	14.45	2.11K	30.52K	37.69K
Jun 20, 2025	KAYE JACK	SALE	14.45	2.11K	30.52K	20.44K
Jun 20, 2025	JACQUES RACHELLE SUZANNE	SALE	14.45	2.11K	30.52K	28.35K
Jun 20, 2025	GUT ROBERT	SALE	14.45	3.34K	48.21K	56.88K
Jun 20, 2025	MEEK DAVID D.	SALE	14.45	2.11K	30.52K	34.19K
Jun 16, 2025	POTTS JEANNETTE	SALE	15.14	4.67K	70.7K	115.07K
Mar 04, 2025	KAPUSTA MATTHEW C	SALE	10.29	28.34K	291.63K	651.45K
Mar 04, 2025	ABI-SAAB WALID	SALE	10.29	1.35K	13.89K	151.9K
Mar 04, 2025	KLEMT CHRISTIAN	SALE	10.29	10.44K	107.41K	217.73K
Mar 04, 2025	POTTS JEANNETTE	SALE	10.29	7.08K	72.81K	119.74K
Feb 27, 2025	KAPUSTA MATTHEW C	SALE	11.32	6.72K	76.04K	580.8K
Feb 27, 2025	KLEMT CHRISTIAN	SALE	11.32	2.92K	33.01K	155.17K
Feb 25, 2025	KAPUSTA MATTHEW C	SALE	10.70	26.73K	285.98K	571.19K
Feb 25, 2025	KLEMT CHRISTIAN	SALE	10.70	14.34K	153.45K	152.37K
Dec 10, 2024	KAPUSTA MATTHEW C	SALE	15.03	100K	1.5M	597.92K
Dec 09, 2024	KAPUSTA MATTHEW C	SALE	7.63	3.42K	26.08K	597.92K
Dec 09, 2024	KLEMT CHRISTIAN	SALE	7.55	1.8K	13.56K	166.71K
Jun 26, 2024	ABI-SAAB WALID	SALE	4.36	1.45K	6.31K	115.25K
Jun 17, 2024	KLEMT CHRISTIAN	SALE	4.80	1.61K	7.73K	164.84K
Jun 17, 2024	CALOZ PIERRE	SALE	4.81	2.94K	14.12K	115.71K
Jun 13, 2024	BALACHANDRAN MADHAVAN	SALE	5.12	2.23K	11.42K	23.76K
Jun 13, 2024	POTTS JEANNETTE	SALE	4.98	4.78K	23.81K	91.82K
Jun 13, 2024	POST LEONARD E	SALE	5.14	2.22K	11.42K	16K
Jun 13, 2024	SPRINGHORN JEREMY P.	SALE	5.12	2.23K	11.42K	23.76K
Jun 13, 2024	GUT ROBERT	SALE	5.12	3.5K	17.94K	44.17K
Jun 13, 2024	KAYE JACK	SALE	5.16	2.22K	11.44K	6.5K
Jun 13, 2024	JACQUES RACHELLE SUZANNE	SALE	5.14	2.22K	11.42K	14.41K
Jun 13, 2024	SOTEROPOULOS PAULA	SALE	5.14	2.22K	11.41K	20.2K
Jun 13, 2024	MEEK DAVID D.	SALE	5.12	2.23K	11.41K	20.25K
Feb 26, 2024	KLEMT CHRISTIAN	SALE	6.38	15.91K	101.48K	116.95K
Feb 26, 2024	CALOZ PIERRE	SALE	6.47	9.46K	61.17K	85.64K
Feb 26, 2024	KAPUSTA MATTHEW C	SALE	6.35	27.9K	177.19K	440.84K
Sep 18, 2023	DOLMETSCH RICARDO	SALE	7.46	5.84K	43.57K	163.4K
Jul 10, 2023	CALOZ PIERRE	SALE	11.36	15.12K	171.73K	95.1K
Jun 16, 2023	SOTEROPOULOS PAULA	SALE	18.99	2.28K	43.2K	22.42K
Jun 16, 2023	KAYE JACK	SALE	18.93	2.28K	43.16K	34.12K
Jun 16, 2023	JACQUES RACHELLE SUZANNE	SALE	18.76	2.3K	43.17K	16.63K
Jun 16, 2023	CALOZ PIERRE	SALE	18.80	2.92K	54.9K	110.22K
Jun 16, 2023	GUT ROBERT	SALE	18.88	3.23K	60.94K	47.67K
Jun 16, 2023	MEEK DAVID D.	SALE	18.85	2.29K	43.17K	22.48K
Jun 16, 2023	POST LEONARD E	SALE	18.83	2.29K	43.14K	18.22K
Jun 16, 2023	BALACHANDRAN MADHAVAN	SALE	18.91	2.28K	43.17K	25.99K
Jun 16, 2023	SPRINGHORN JEREMY P.	SALE	18.88	2.29K	43.16K	25.99K
Jun 16, 2023	KLEMT CHRISTIAN	SALE	18.94	1.59K	30.06K	132.85K
Mar 07, 2023	KLEMT CHRISTIAN	SALE	21.36	986	21.06K	134.44K
Mar 07, 2023	DOLMETSCH RICARDO	SALE	21.04	837	17.61K	169.25K
Mar 07, 2023	KAPUSTA MATTHEW C	SALE	21.39	2.52K	53.92K	468.74K
Mar 07, 2023	CALOZ PIERRE	SALE	21.33	990	21.12K	113.14K
Mar 07, 2023	KUTA ALEXANDER EDWARD III	SALE	21.36	585	12.5K	90.38K
Feb 28, 2023	KAPUSTA MATTHEW C	SALE	20.90	5.02K	104.94K	471.26K
Feb 28, 2023	KLEMT CHRISTIAN	SALE	20.90	1.37K	28.61K	135.43K
Feb 28, 2023	KUTA ALEXANDER EDWARD III	SALE	21.04	1.21K	25.5K	90.97K
Feb 28, 2023	GUT ROBERT	SALE	21.16	1.43K	30.28K	42.2K
Feb 27, 2023	MEEK DAVID D.	SALE	19.71	389	7.67K	16.07K
Feb 27, 2023	POST LEONARD E	SALE	19.73	389	7.67K	11.81K
Feb 27, 2023	KLEMT CHRISTIAN	SALE	20.10	9.82K	197.46K	136.8K
Feb 27, 2023	KUTA ALEXANDER EDWARD III	SALE	19.99	5.51K	110.22K	92.18K
Feb 27, 2023	BALACHANDRAN MADHAVAN	SALE	19.99	384	7.68K	19.57K
Feb 27, 2023	SOTEROPOULOS PAULA	SALE	19.97	384	7.67K	16K
Feb 27, 2023	GUT ROBERT	SALE	19.79	537	10.63K	43.63K
Feb 27, 2023	KAYE JACK	SALE	19.99	384	7.68K	27.7K
Feb 27, 2023	JACQUES RACHELLE SUZANNE	SALE	20.02	384	7.69K	10.23K
Feb 27, 2023	SPRINGHORN JEREMY P.	SALE	20.41	384	7.84K	19.57K
Feb 27, 2023	DOLMETSCH RICARDO	SALE	19.58	6.94K	135.96K	170.08K
Feb 27, 2023	KAPUSTA MATTHEW C	SALE	20.24	1.39K	28.03K	476.29K
Feb 27, 2023	CALOZ PIERRE	SALE	20.80	81	1.68K	114.13K
Jan 18, 2023	SOTEROPOULOS PAULA	SALE	22.59	6K	135.54K	16.38K
Dec 14, 2022	SOTEROPOULOS PAULA	SALE	23.43	3.8K	89.03K	16.38K
Dec 09, 2022	KLEMT CHRISTIAN	SALE	22.35	2.61K	58.29K	107.18K
Dec 09, 2022	KUTA ALEXANDER EDWARD III	SALE	22.34	2.34K	52.23K	95.65K
Dec 09, 2022	KAPUSTA MATTHEW C	SALE	22.44	6.65K	149.18K	368.48K
Dec 09, 2022	DOLMETSCH RICARDO	SALE	22.30	2.22K	49.48K	127.41K
Dec 09, 2022	CALOZ PIERRE	SALE	22.22	2.94K	65.35K	68.87K
Nov 29, 2022	SOTEROPOULOS PAULA	SALE	25.38	6.2K	157.36K	16.38K
Sep 21, 2022	KUTA ALEXANDER EDWARD III	SALE	18.65	2.31K	43.01K	92.89K
Jul 28, 2022	KUTA ALEXANDER EDWARD III	SALE	25.01	406	10.15K	95.2K
Jul 27, 2022	KUTA ALEXANDER EDWARD III	SALE	25.00	10.4K	260.1K	95.2K
Jul 21, 2022	KUTA ALEXANDER EDWARD III	SALE	25.00	5.64K	141.08K	95.2K
Jun 16, 2022	KLEMT CHRISTIAN	SALE	13.20	1.69K	22.27K	104.69K
Jun 16, 2022	CALOZ PIERRE	SALE	13.21	7.58K	100.07K	64.51K
Feb 28, 2022	SOTEROPOULOS PAULA	SALE	16.87	596	10.05K	7.3K
Feb 28, 2022	GUT ROBERT	SALE	16.70	1.6K	26.75K	35.09K
Feb 28, 2022	KAYE JACK	SALE	16.76	600	10.06K	19K
Feb 28, 2022	POST LEONARD E	SALE	16.64	795	13.23K	3.12K
Feb 28, 2022	KAPUSTA MATTHEW C	SALE	16.70	10.2K	170.26K	360.55K
Feb 28, 2022	DOLMETSCH RICARDO	SALE	16.68	1.48K	24.75K	122.33K
Feb 28, 2022	KLEMT CHRISTIAN	SALE	16.80	4.08K	68.46K	106.38K
Feb 28, 2022	MEEK DAVID D.	SALE	16.70	602	10.05K	7.38K
Feb 28, 2022	KUTA ALEXANDER EDWARD III	SALE	16.72	3.41K	56.93K	95.16K
Feb 28, 2022	SPRINGHORN JEREMY P.	SALE	16.70	602	10.05K	10.88K
Feb 28, 2022	BALACHANDRAN MADHAVAN	SALE	16.70	602	10.05K	10.88K
Jan 26, 2022	KUTA ALEXANDER EDWARD III	SALE	18.02	2.95K	53.07K	63.7K
Jan 26, 2022	KAPUSTA MATTHEW C	SALE	18.10	10.9K	197.31K	245.68K
Jan 26, 2022	KLEMT CHRISTIAN	SALE	18.03	3.96K	71.45K	66.82K
Jan 26, 2022	GUT ROBERT	SALE	18.12	2.35K	42.55K	35.15K
Dec 15, 2021	KUTA ALEXANDER EDWARD III	SALE	27.90	6K	167.4K	66.64K
Nov 15, 2021	KUTA ALEXANDER EDWARD III	SALE	31.81	6K	190.86K	66.64K
Oct 15, 2021	KUTA ALEXANDER EDWARD III	SALE	30.65	6K	183.9K	66.64K
Sep 21, 2021	KLEMT CHRISTIAN	SALE	38.00	2.4K	91.2K	70.78K
Sep 21, 2021	GUT ROBERT	SALE	36.61	4.5K	164.75K	37.5K
Sep 21, 2021	KUTA ALEXANDER EDWARD III	SALE	36.71	2.23K	81.83K	66.64K
Sep 16, 2021	DOLMETSCH RICARDO	SALE	37.10	8.6K	319.17K	69.13K
Sep 15, 2021	KUTA ALEXANDER EDWARD III	SALE	36.32	6K	217.92K	68.87K
Aug 18, 2021	KAPUSTA MATTHEW C	SALE	28.64	117	3.35K	256.58K
Aug 16, 2021	KUTA ALEXANDER EDWARD III	SALE	28.84	6K	173.04K	68.87K
Jul 15, 2021	KUTA ALEXANDER EDWARD III	SALE	27.22	6K	163.32K	68.87K
Jul 14, 2021	KAPUSTA MATTHEW C	SALE	27.77	1K	27.77K	257.58K
Jun 17, 2021	KAPUSTA MATTHEW C	SALE	35.00	1.9K	66.5K	258.58K
Jun 16, 2021	KAPUSTA MATTHEW C	SALE	34.89	1.99K	69.54K	260.48K
Jun 15, 2021	KUTA ALEXANDER EDWARD III	SALE	35.43	6K	212.58K	68.87K
May 17, 2021	KUTA ALEXANDER EDWARD III	SALE	31.66	6K	189.96K	68.87K
May 12, 2021	KAPUSTA MATTHEW C	SALE	32.29	2.25K	72.65K	263.93K
Apr 15, 2021	KUTA ALEXANDER EDWARD III	SALE	35.06	6K	210.36K	68.87K
Apr 14, 2021	KAPUSTA MATTHEW C	SALE	35.07	3.63K	127.37K	267.9K
Mar 17, 2021	KAPUSTA MATTHEW C	SALE	34.54	6	207.24	271.53K
Mar 02, 2021	SOTEROPOULOS PAULA	SALE	37.60	504	18.95K	6.36K
Mar 02, 2021	MEEK DAVID D.	SALE	37.50	505	18.94K	6.45K
Mar 02, 2021	BALACHANDRAN MADHAVAN	SALE	37.50	505	18.94K	9.95K
Mar 02, 2021	ASTLEY-SPARKE PHILIP	SALE	37.60	504	18.95K	9.95K
Mar 02, 2021	KAYE JACK	SALE	37.60	504	18.95K	18.07K
Mar 02, 2021	GUT ROBERT	SALE	36.98	1.3K	48.07K	42K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES112.87K6

NET SHARES-112.87K6

SHARES HELD1.3M6

% NET SHARES-108.7%0%

Frequently Asked Questions

Stock Outstanding Shares

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares16.51

Short Percent Of Float16.73

Shares Outstanding54.87M

Shares Float38.74M

Shares Short9.06M

Short Ratio8.42

16.73%

Short % of Float

16.51%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

6.07% Percentage of Shares held by All Insiders

96.91% Percentage of Shares held by All Institutions

103.18% Percentage of Float held by Institutions

186

Number of Institutions Holding Shares

Institutional Ownership

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.54%	295.13K	17.23M	153.32K	+108.12%
Sep 30, 2025	BALYASNY ASSET MANAGEMENT L.P.	0.57%	333.24K	19.45M	-203.73K	-37.94%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.61%	357.69K	20.88M	64.75K	+22.11%
Sep 30, 2025	CAPTION MANAGEMENT, LLC	0.65%	381K	22.24M	-1.11M	-74.52%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.66%	385.61K	22.51M	-118.06K	-23.44%
Sep 30, 2025	DARWIN GLOBAL MANAGEMENT, LTD.	0.68%	400K	23.76M	400K	+100.00%
Sep 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.56%	913.18K	53.3M	913.18K	+100.00%
Sep 30, 2025	DIAMOND HILL CAPITAL MANAGEMENT INC	0.06%	33.33K	1.95M	-49.32K	-59.67%
Sep 30, 2025	LEGAL & GENERAL GROUP PLC	0.07%	35.62K	2.08M	0	0
Sep 30, 2025	PARKMAN HEALTHCARE PARTNERS LLC	0.59%	345.36K	20.16M	-98.07K	-22.12%
Sep 30, 2025	MONACO ASSET MANAGEMENT SAM	0.07%	39.91K	2.33M	-30.09K	-42.98%
Sep 30, 2025	MONASHEE INVESTMENT MANAGEMENT LLC	0.07%	40K	2.33M	40K	+100.00%
Sep 30, 2025	WINTON GROUP LTD	0.07%	40.98K	2.39M	40.98K	+100.00%
Sep 30, 2025	LPL FINANCIAL LLC	0.08%	46.11K	2.69M	46.11K	+100.00%
Sep 30, 2025	CI INVESTMENTS INC.	0.09%	47.44K	2.77M	47.44K	+100.00%
Sep 30, 2025	HENNION & WALSH ASSET MANAGEMENT, INC.	0.09%	51.61K	3.01M	21.24K	+69.95%
Sep 30, 2025	HEADLANDS TECHNOLOGIES LLC	0.1%	57.41K	3.35M	14.96K	+35.26%
Sep 30, 2025	STIFEL FINANCIAL CORP	0.11%	58.28K	3.4M	-8.71K	-13.00%
Sep 30, 2025	PATIENT SQUARE CAPITAL LP	0.14%	75K	4.38M	75K	+100.00%
Sep 30, 2025	SWISS NATIONAL BANK	0.14%	76.3K	4.45M	-1.2K	-1.55%
Sep 30, 2025	BIRCHVIEW CAPITAL, LP	0.14%	78.73K	4.6M	-19.97K	-20.23%
Sep 30, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.15%	82.86K	4.84M	14.05K	+20.42%
Sep 30, 2025	SANDERS MORRIS HARRIS LLC	0.16%	87.05K	5.08M	87.05K	+100.00%
Sep 30, 2025	ATIKA CAPITAL MANAGEMENT LLC	0.16%	90K	5.25M	90K	+100.00%
Sep 30, 2025	JEFFERIES FINANCIAL GROUP INC.	0.17%	90.54K	5.28M	-2.01M	-95.68%
Sep 30, 2025	TD ASSET MANAGEMENT INC	0.17%	95.14K	5.55M	95.14K	+100.00%
Sep 30, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.19%	102.12K	5.96M	34.86K	+51.83%
Sep 30, 2025	QUINN OPPORTUNITY PARTNERS LLC	0.2%	107.6K	6.28M	107.6K	+100.00%
Sep 30, 2025	MARSHALL WACE, LLP	0.2%	108.21K	6.32M	-114.77K	-51.47%
Sep 30, 2025	VOSS CAPITAL, LLC	0.23%	125K	1.74M	0	0
Sep 30, 2025	ROSALIND ADVISORS, INC.	0.23%	125K	7.3M	125K	+100.00%
Sep 30, 2025	GROUP ONE TRADING, L.P.	0.26%	140.23K	8.19B	76.55K	+120.20%
Sep 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0.27%	149.85K	8.75M	43.36K	+40.72%
Sep 30, 2025	LORD, ABBETT & CO. LLC	0.32%	176.03K	10.28M	176.03K	+100.00%
Sep 30, 2025	TWO SIGMA INVESTMENTS, LP	1.53%	897.54K	52.39M	-43.42K	-4.61%
Sep 30, 2025	PRIVIUM FUND MANAGEMENT B.V.	0.66%	386K	22.53M	-61.49K	-13.74%
Sep 30, 2025	BARCLAYS PLC	0.17%	93.2K	5.44M	-68.7K	-42.43%
Sep 30, 2025	CENTIVA CAPITAL, LP	0.43%	233.6K	13.64M	213.6K	+1,068.00%
Sep 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.46%	254.08K	14.83M	148.14K	+139.84%
Sep 30, 2025	CATALIO CAPITAL MANAGEMENT, LP	0.52%	282.94K	16.52M	-134.5K	-32.22%
Sep 30, 2025	683 CAPITAL MANAGEMENT, LLC	1.83%	1.07M	62.46M	-215K	-16.73%
Sep 30, 2025	MORGAN STANLEY	0.55%	321.5K	18.77M	-586.78K	-64.60%
Sep 30, 2025	TWO SIGMA ADVISERS, LP	0.7%	409.5K	23.9M	-250.2K	-37.93%
Sep 30, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.78%	455K	26.56M	252.44K	+124.62%
Sep 30, 2025	ORBIMED ADVISORS LLC	0.78%	458.5K	26.76M	458.5K	+100.00%
Sep 30, 2025	STEMPOINT CAPITAL LP	0.89%	522.16K	30.48M	-50.46K	-8.81%
Sep 30, 2025	FARALLON CAPITAL MANAGEMENT LLC	0.97%	565K	32.98M	551K	+3,935.71%
Sep 30, 2025	UBS GROUP AG	0.37%	204.99K	11.97M	-58.68K	-22.25%
Sep 30, 2025	MACQUARIE GROUP LTD	0.47%	258.21K	15.07M	-447.96K	-63.43%
Sep 30, 2025	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	1.03%	600K	35.02M	-750K	-55.56%
Sep 30, 2025	CITADEL ADVISORS LLC	0.73%	429.71K	25.08M	-126.16K	-22.70%
Sep 30, 2025	ARTIA GLOBAL PARTNERS LP	1.13%	658.84K	38.46M	658.84K	+100.00%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.23%	721.65K	42.14M	118.44K	+19.64%
Sep 30, 2025	BOXER CAPITAL MANAGEMENT, LLC	1.37%	800K	46.7M	-99.5K	-11.06%
Sep 30, 2025	EVERSEPT PARTNERS, LP	1.5%	877.37K	51.21M	877.37K	+100.00%
Sep 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	1.51%	884K	51.6M	341.7K	+63.01%
Sep 30, 2025	JENNISON ASSOCIATES LLC	1.71%	999.48K	58.34M	859.42K	+613.61%
Sep 30, 2025	NANTAHALA CAPITAL MANAGEMENT, LLC	1.72%	1.01M	58.81M	-1.04M	-50.90%
Sep 30, 2025	ECOR1 CAPITAL, LLC	6.82%	3.99M	232.84M	0	0
Sep 30, 2025	RTW INVESTMENTS, LP	7.56%	4.42M	258.29M	-733.26K	-14.22%
Sep 30, 2025	AVORO CAPITAL ADVISORS LLC	7.6%	4.44M	259.42M	819.44K	+22.61%
Sep 30, 2025	DEEP TRACK CAPITAL, LP	0.83%	483.09K	28.2M	483.09K	+100.00%
Sep 30, 2025	JANE STREET GROUP, LLC	0.86%	505.2K	29.49M	478.1K	+1,764.21%
Sep 30, 2025	NATIONALE-NEDERLANDEN POWSZECHNE TOWARZYSTWO EMERYTALNE S.A.	0.89%	521.68K	30.45M	521.68K	+100.00%
Sep 30, 2025	VANGUARD GROUP INC	1.92%	1.13M	65.67M	152.42K	+15.67%
Sep 30, 2025	JPMORGAN CHASE & CO	2.1%	1.15M	67.09M	-658.33K	-36.42%
Sep 30, 2025	FRED ALGER MANAGEMENT, LLC	2.21%	1.29M	75.32M	1.29M	+100.00%
Sep 30, 2025	STATE STREET CORP	2.47%	1.44M	84.29M	301.2K	+26.36%
Sep 30, 2025	SIREN, L.L.C.	0.5%	275.2K	16.06M	275.2K	+100.00%
Sep 30, 2025	FMR LLC	10.36%	6.06M	353.7M	4.88M	+411.63%
Sep 30, 2025	DLD ASSET MANAGEMENT, LP	0.11%	60.4K	3.52M	60.4K	+100.00%
Sep 30, 2025	SEI INVESTMENTS CO	0.12%	67.27K	3.93M	67.27K	+100.00%
Sep 30, 2025	HUDSON BAY CAPITAL MANAGEMENT LP	0.12%	67.7K	3.95M	67.7K	+100.00%
Sep 30, 2025	DIADEMA PARTNERS LP	0.51%	300K	17.51M	300K	+100.00%
Sep 30, 2025	LOGOS GLOBAL MANAGEMENT LP	0.51%	300K	17.51M	300K	+100.00%
Sep 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.51%	300K	17.51M	165K	+122.22%
Sep 30, 2025	SOFINNOVA INVESTMENTS, INC.	0.51%	300K	17.51M	300K	+100.00%
Sep 30, 2025	SIMPLEX TRADING, LLC	0.12%	68K	3.97M	3.74K	+5.81%
Sep 30, 2025	BLACKROCK, INC.	2.47%	1.45M	84.41M	112.44K	+8.43%
Sep 30, 2025	FRANKLIN RESOURCES INC	3.4%	1.99M	116.07M	383.07K	+23.86%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	1.13%	662.21K	38.65M	305.75K	+85.77%
Sep 30, 2025	ABRDN PLC	5.02%	2.94M	171.59M	189.03K	+6.87%
Jun 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.92%	503.67K	7.02M	22.22K	+4.62%
Jun 30, 2025	PARKMAN HEALTHCARE PARTNERS LLC	0.81%	443.42K	6.18M	239.59K	+117.54%
Jun 30, 2025	ROYAL BANK OF CANADA	0.71%	391.61K	5.46M	342.28K	+693.85%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.65%	356.46K	4.97M	96.83K	+37.29%
Jun 30, 2025	BANK OF NEW YORK MELLON CORP	0.64%	348.33K	4.86M	348.33K	+100.00%
Jun 30, 2025	FMR LLC	2.16%	1.18M	16.51M	-16.58K	-1.38%
Jun 30, 2025	MORGAN STANLEY	1.66%	908.28K	12.66M	304.77K	+50.50%
Jun 30, 2025	ECOR1 CAPITAL, LLC	7.28%	3.99M	55.61M	0	0
Jun 30, 2025	SCHONFELD STRATEGIC ADVISORS LLC	0.25%	134.95K	1.88M	92.8K	+220.18%
Jun 30, 2025	VOSS CAPITAL, LLC	0.23%	125K	1.74M	125K	+100.00%
Jun 30, 2025	J. GOLDMAN & CO LP	0.22%	121.6K	1.7M	67.6K	+125.19%
Jun 30, 2025	IKARIAN CAPITAL, LLC	0.22%	119.99K	1.67M	119.99K	+100.00%
Jun 30, 2025	BIRCHVIEW CAPITAL, LP	0.18%	98.7K	1.38M	10K	+11.27%
Jun 30, 2025	VERITION FUND MANAGEMENT LLC	0.17%	92.59K	1.29M	-3.94K	-4.08%
Jun 30, 2025	RTW INVESTMENTS, LP	9.41%	5.16M	71.91M	892.8K	+20.93%
Jun 30, 2025	VESTAL POINT CAPITAL, LP	6.75%	3.7M	51.58M	-1.09M	-22.80%
Jun 30, 2025	Y-INTERCEPT (HONG KONG) LTD	0.11%	62.54K	871.78K	62.54K	+100.00%
Jun 30, 2025	SECTORAL ASSET MANAGEMENT INC	0.1%	55.45K	772.97K	-2.1K	-3.65%
Jun 30, 2025	CENTIVA CAPITAL, LP	0.09%	50K	697K	50K	+100.00%
Jun 30, 2025	HEADLANDS TECHNOLOGIES LLC	0.08%	42.44K	591.67K	31.95K	+304.38%
Jun 30, 2025	SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC	0.07%	38.53K	537.16K	0	0
Jun 30, 2025	AQUATIC CAPITAL MANAGEMENT LLC	0.06%	35.26K	491.55K	24.67K	+232.97%
Jun 30, 2025	HENNION & WALSH ASSET MANAGEMENT, INC.	0.06%	30.37K	423.34K	30.37K	+100.00%
Jun 30, 2025	HRT FINANCIAL LP	0.05%	28.42K	396K	28.42K	+100.00%
Jun 30, 2025	NANTAHALA CAPITAL MANAGEMENT, LLC	3.74%	2.05M	28.6M	-704.11K	-25.55%
Jun 30, 2025	CATALIO CAPITAL MANAGEMENT, LP	0.76%	417.44K	5.82M	-412.88K	-49.73%
Jun 30, 2025	BOXER CAPITAL MANAGEMENT, LLC	1.64%	899.5K	12.54M	149.5K	+19.93%
Jun 30, 2025	JPMORGAN CHASE & CO	3.3%	1.81M	25.2M	1.49M	+471.69%
Jun 30, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.51%	279K	3.89M	182.8K	+190.02%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.53%	292.93K	4.08M	12.93K	+4.62%
Jun 30, 2025		0.76%	417.44K	5.82M	-412.88K	-49.73%
Jun 30, 2025	MACQUARIE GROUP LTD	1.29%	706.17K	9.84M	0	0
Jun 30, 2025	CITADEL ADVISORS LLC	1.01%	555.87K	7.75M	-229.46K	-29.22%
Jun 30, 2025	STEMPOINT CAPITAL LP	1.04%	572.62K	7.98M	-158.42K	-21.67%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.1%	603.21K	8.41M	-7.76K	-1.27%
Jun 30, 2025	TWO SIGMA ADVISERS, LP	1.2%	659.7K	9.2M	-8.79K	-1.32%
Jun 30, 2025	SCHRODER INVESTMENT MANAGEMENT GROUP	1.26%	693.28K	9.66M	-496.84K	-41.75%
Jun 30, 2025	TWO SIGMA INVESTMENTS, LP	1.72%	940.96K	13.12M	24.46K	+2.67%
Jun 30, 2025	VANGUARD GROUP INC	1.77%	972.69K	13.56M	27.23K	+2.88%
Jun 30, 2025	STATE STREET CORP	2.09%	1.14M	15.93M	-86.78K	-7.06%
Jun 30, 2025	683 CAPITAL MANAGEMENT, LLC	2.34%	1.29M	17.91M	-265K	-17.10%
Jun 30, 2025	BLACKROCK, INC.	2.43%	1.33M	18.59M	-103.32K	-7.19%
Jun 30, 2025	AMERIPRISE FINANCIAL INC	1.39%	761.95K	10.62M	212.22K	+38.60%
Jun 30, 2025	FRANKLIN RESOURCES INC	2.93%	1.61M	22.38M	-382.17K	-19.23%
Jun 30, 2025	JEFFERIES FINANCIAL GROUP INC.	3.82%	2.1M	29.22M	2.1M	+100.00%
Jun 30, 2025	ABRDN PLC	5.02%	2.75M	38.34M	535.16K	+24.15%
Jun 30, 2025	AVORO CAPITAL ADVISORS LLC	6.61%	3.63M	50.53M	1.45M	+66.67%
Jun 30, 2025	PFM HEALTH SCIENCES, LP	0.32%	174.33K	2.43M	-425.64K	-70.94%
Jun 30, 2025	MOORE CAPITAL MANAGEMENT, LP	0.32%	175K	2.44M	25K	+16.67%
Jun 30, 2025	WOODLINE PARTNERS LP	0.32%	175.81K	2.45M	0	0
Jun 30, 2025	SQUAREPOINT OPS LLC	0.32%	176K	2.45M	-2.33K	-1.31%
Jun 30, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.37%	202.57K	2.82M	-835	-0.41%
Jun 30, 2025	AVIDITY PARTNERS MANAGEMENT LP	0.38%	207K	2.89M	-129.2K	-38.43%
Jun 30, 2025	MARSHALL WACE, LLP	0.41%	222.98K	3.11M	163.75K	+276.46%
Jun 30, 2025	UBS GROUP AG	0.48%	263.67K	3.68M	36.77K	+16.21%
Jun 30, 2025	CAPTION MANAGEMENT, LLC	0.32%	176.91K	2.47M	156.55K	+768.96%
Jun 30, 2025	UBS OCONNOR LLC	0.15%	80K	124K	15K	+23.08%
Jun 30, 2025	DIAMOND HILL CAPITAL MANAGEMENT INC	0.15%	82.65K	1.15M	0	0
Jun 30, 2025	SHAY CAPITAL LLC	0.18%	99.38K	1.39M	17.53K	+21.42%
Jun 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.18%	100K	1.39M	100K	+100.00%
Jun 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.19%	105.94K	1.48M	-24.14K	-18.56%
Jun 30, 2025	PEAK6 LLC	0.21%	112.9K	1.57M	92.1K	+442.79%
Jun 30, 2025	JENNISON ASSOCIATES LLC	0.26%	140.06K	1.95M	140.06K	+100.00%
Jun 30, 2025	HUDSON BAY CAPITAL MANAGEMENT LP	0.27%	148.18K	2.07M	-3.52K	-2.32%
Jun 30, 2025	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	2.46%	1.35M	18.82M	100K	+8.00%
Jun 30, 2025	SOFINNOVA INVESTMENTS, INC.	2.84%	1.56M	21.72M	1.01M	+185.53%
Jun 30, 2025	MONACO ASSET MANAGEMENT SAM	0.13%	70K	975.8K	-5K	-6.67%
Jun 30, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.13%	68.81K	959.17K	-13.78K	-16.69%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.99%	542.3K	7.56M	385.6K	+246.08%
Jun 30, 2025	BALYASNY ASSET MANAGEMENT L.P.	0.98%	536.97K	7.49M	512.04K	+2,054.08%
Jun 30, 2025	PALE FIRE CAPITAL SE	0.97%	529.8K	7.39M	67.44K	+14.59%
Jun 30, 2025	PRIVIUM FUND MANAGEMENT B.V.	0.82%	447.49K	6.26M	-131.65K	-22.73%
Mar 31, 2025	STEMPOINT CAPITAL LP	1.38%	731.04K	7.75M	641.04K	+712.27%
Mar 31, 2025	VESTAL POINT CAPITAL, LP	9.02%	4.79M	50.8M	1.77M	+58.43%
Mar 31, 2025	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	2.35%	1.25M	13.25M	150K	+13.64%
Mar 31, 2025	TWO SIGMA INVESTMENTS, LP	1.73%	916.5K	9.71M	37.62K	+4.28%
Mar 31, 2025		1.41%	750K	7.95M	0	0
Mar 31, 2025	CITADEL ADVISORS LLC	1.48%	785.32K	8.32M	773.31K	+6,441.06%
Mar 31, 2025	CUBIST SYSTEMATIC STRATEGIES, LLC	0.46%	241.68K	2.56M	241.68K	+100.00%
Mar 31, 2025	PALE FIRE CAPITAL SE	0.87%	462.36K	4.9M	-118.35K	-20.38%
Mar 31, 2025	ACADIAN ASSET MANAGEMENT LLC	0.47%	250.1K	2.65M	-7.72K	-2.99%
Mar 31, 2025	ECOR1 CAPITAL, LLC	7.51%	3.99M	42.28M	588.97K	+17.32%
Mar 31, 2025	NANTAHALA CAPITAL MANAGEMENT, LLC	5.19%	2.76M	29.21M	302.6K	+12.33%
Mar 31, 2025	AVORO CAPITAL ADVISORS LLC	4.1%	2.18M	23.06M	0	0
Mar 31, 2025	BLACKROCK, INC.	2.71%	1.44M	15.23M	21.42K	+1.51%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.15%	610.97K	6.48M	90.42K	+17.37%
Mar 31, 2025	MORGAN STANLEY	1.14%	603.52K	6.4M	-93.81K	-13.45%
Mar 31, 2025	PRIVIUM FUND MANAGEMENT B.V.	1.09%	579.14K	6.14M	-163.02K	-21.97%
Mar 31, 2025	AMERIPRISE FINANCIAL INC	1.04%	549.73K	5.83M	17.9K	+3.37%
Mar 31, 2025	SOFINNOVA INVESTMENTS, INC.	1.03%	545.77K	5.79M	545.77K	+100.00%
Mar 31, 2025	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.94%	500.98K	5.31M	323.8K	+182.75%
Mar 31, 2025	LORD, ABBETT & CO. LLC	0.75%	400.79K	4.25M	86.37K	+27.47%
Mar 31, 2025	AVIDITY PARTNERS MANAGEMENT LP	0.63%	336.2K	3.56M	114.2K	+51.44%
Mar 31, 2025	ASSENAGON ASSET MANAGEMENT S.A.	0.63%	334.89K	3.55M	261.32K	+355.20%
Mar 31, 2025	WALLEYE CAPITAL LLC	0.5%	266.73K	2.83M	136.3K	+104.51%
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	0.5%	265.67K	2.82M	-198.87K	-42.81%
Mar 31, 2025	PARKMAN HEALTHCARE PARTNERS LLC	0.38%	203.83K	2.16M	-71.17K	-25.88%
Mar 31, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.38%	203.4K	2.16M	103.4K	+103.40%
Mar 31, 2025	RTW INVESTMENTS, LP	8.03%	4.27M	45.21M	3.36M	+372.04%
Mar 31, 2025	ABRDN PLC	4.17%	2.22M	23.48M	706.22K	+46.79%
Mar 31, 2025	AFFINITY ASSET ADVISORS, LLC	0.75%	400K	4.24M	400K	+100.00%
Mar 31, 2025	UBS GROUP AG	0.43%	226.9K	2.41M	83.07K	+57.76%
Mar 31, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.38%	200K	2.12M	200K	+100.00%
Mar 31, 2025	MACQUARIE GROUP LTD	1.33%	706.17K	7.49B	0	0
Mar 31, 2025	TWO SIGMA ADVISERS, LP	1.26%	668.49K	7.09M	-88.41K	-11.68%
Mar 31, 2025	PFM HEALTH SCIENCES, LP	1.13%	599.97K	6.36M	316.81K	+111.88%
Mar 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.91%	481.45K	5.1M	13.09K	+2.80%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0.72%	380.85K	4.04M	311.79K	+451.45%
Mar 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.7%	372K	3.94M	-11.7K	-3.05%
Mar 31, 2025	JPMORGAN CHASE & CO	0.6%	316.2K	3.35M	-137.59K	-30.32%
Mar 31, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0.57%	303.63K	3.22M	303.63K	+100.00%
Mar 31, 2025	IKARIAN CAPITAL, LLC	0.56%	300K	3.18M	300K	+100.00%
Mar 31, 2025	FRANKLIN RESOURCES INC	3.74%	1.99M	21.07M	0	0
Mar 31, 2025	683 CAPITAL MANAGEMENT, LLC	2.92%	1.55M	16.43M	25K	+1.64%
Mar 31, 2025	INVESCO LTD.	0.91%	485.31K	5.14M	-128.3K	-20.91%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.53%	280K	2.97M	10.02K	+3.71%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.49%	259.64K	2.75M	180.31K	+227.31%
Mar 31, 2025	STATE STREET CORP	2.32%	1.23M	13.03M	1.04M	+538.64%
Mar 31, 2025	FMR LLC	2.26%	1.2M	12.73M	234.29K	+24.24%
Mar 31, 2025	SCHRODER INVESTMENT MANAGEMENT GROUP	2.24%	1.19M	14.84M	356.05K	+42.69%
Mar 31, 2025	VANGUARD GROUP INC	1.78%	945.47K	10.02M	-161.14K	-14.56%
Mar 31, 2024	SIMPLEX TRADING, LLC	0.18%	84.59K	439K	62.99K	+291.62%
Mar 31, 2024	ACADIAN ASSET MANAGEMENT LLC	1.28%	613.49K	3.19M	350.29K	+133.09%
Mar 31, 2024	MACQUARIE GROUP LTD	1.48%	706.17K	3.67M	0	0
Mar 31, 2024	AMERIPRISE FINANCIAL INC	1.48%	709.44K	3.69M	-110.83K	-13.51%
Mar 31, 2024	BNP PARIBAS ARBITRAGE, SNC	1.54%	736.72K	3.83M	30.05K	+4.25%
Mar 31, 2024	D. E. SHAW & CO., INC.	1.78%	850.1K	4.42M	289.77K	+51.71%
Mar 31, 2024	STIFEL FINANCIAL CORP	0.05%	23.52K	122.28K	286	+1.23%
Mar 31, 2024	UBS GROUP AG	0.06%	26.71K	138.88K	-141.29K	-84.10%
Mar 31, 2024	RAYMOND JAMES & ASSOCIATES	0.06%	27.37K	142.31K	-24.86K	-47.60%
Mar 31, 2024	BALYASNY ASSET MANAGEMENT L.P.	0.06%	28.79K	149.71K	9.77K	+51.37%
Mar 31, 2024	FMR LLC	0.06%	28.81K	149.79K	-19.98K	-40.95%
Mar 31, 2024	BANK OF MONTREAL /CAN/	0.07%	32.4K	175.28K	10.6K	+48.62%
Mar 31, 2024	CI PRIVATE WEALTH, LLC	0.07%	32.6K	169.52K	32.6K	+100.00%
Mar 31, 2024	WORTH VENTURE PARTNERS, LLC	0.07%	34.3K	178.36K	34.3K	+100.00%
Mar 31, 2024	HARBOR CAPITAL ADVISORS, INC.	0.07%	34.87K	181K	3.98K	+12.90%
Mar 31, 2024	CLEAR HARBOR ASSET MANAGEMENT, LLC	0.07%	35.5K	184.6K	22.6K	+175.19%
Mar 31, 2024	HENRY JAMES INTERNATIONAL MANAGEMENT INC.	0.08%	39.52K	205.49K	-1.77K	-4.28%
Mar 31, 2024	CITIGROUP INC	0.08%	39.99K	207.94K	-703.92K	-94.62%
Mar 31, 2024	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.09%	40.65K	211.39K	23.97K	+143.67%
Mar 31, 2024	HRT FINANCIAL LP	0.09%	45.04K	234K	-11.85K	-20.83%
Mar 31, 2024	ALLIANZ ASSET MANAGEMENT GMBH	0.11%	50.64K	263.34K	0	0
Mar 31, 2024	COVESTOR LTD	0.11%	53.69K	279K	27.27K	+103.19%
Mar 31, 2024	AMERICAN CENTURY COMPANIES INC	0.12%	59.06K	307.1K	14.56K	+32.72%
Mar 31, 2024	Y-INTERCEPT (HONG KONG) LTD	0.12%	59.29K	308.32K	46.11K	+349.86%
Mar 31, 2024	PALE FIRE CAPITAL SE	0.14%	65.6K	341.12K	0	0
Mar 31, 2024	SANDERS MORRIS HARRIS LLC	0.14%	68.07K	353.96K	0	0
Mar 31, 2024	DIAMOND HILL CAPITAL MANAGEMENT INC	0.16%	76.63K	398.48K	22.45K	+41.42%
Mar 31, 2024	SIGMA PLANNING CORP	0.17%	82.66K	429.81K	53.91K	+187.55%
Mar 31, 2024	SCHRODER INVESTMENT MANAGEMENT GROUP	2.6%	1.24M	6.46M	0	0
Mar 31, 2024	NORTHERN TRUST CORP	0.18%	84.9K	441.5K	-2.23K	-2.56%
Mar 31, 2024	683 CAPITAL MANAGEMENT, LLC	4.13%	1.98M	10.27M	282K	+16.66%
Mar 31, 2024	VESTAL POINT CAPITAL, LP	9.88%	4.73M	24.57M	800K	+20.38%
Mar 31, 2024	JUMP FINANCIAL, LLC	0.21%	99.68K	518.32K	-9.21K	-8.46%
Mar 31, 2024	INVESCO LTD.	0.23%	108.6K	564.71K	72.8K	+203.35%
Mar 31, 2024	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.24%	116.71K	607K	116.71K	+100.00%
Mar 31, 2024	PDT PARTNERS, LLC	0.25%	121.87K	633.7K	21.66K	+21.62%
Mar 31, 2024	BANQUE PICTET & CIE SA	0.28%	132.18K	687.34K	-12.4K	-8.58%
Mar 31, 2024	TANG CAPITAL MANAGEMENT LLC	0.28%	133.92K	696.39K	-466.08K	-77.68%
Mar 31, 2024	MIRAE ASSET GLOBAL INVESTMENTS CO., LTD.	0.33%	157.31K	3.14M	66.96K	+74.11%
Mar 31, 2024	POINT72 ASSET MANAGEMENT, L.P.	0.39%	185.22K	963.17K	-746.06K	-80.11%
Mar 31, 2024	BOOTHBAY FUND MANAGEMENT, LLC	0.4%	192.81K	1M	156.08K	+424.82%
Mar 31, 2024	STATE STREET CORP	0.43%	203.8K	1.06M	-3.28M	-94.14%
Mar 31, 2024	JANE STREET GROUP, LLC	0.45%	215.67K	1.12M	110.47K	+105.00%
Mar 31, 2024	CARLSON CAPITAL L P	0.48%	227.4K	1.18M	32.4K	+16.62%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.49%	235.49K	1.22M	13.1K	+5.89%
Mar 31, 2024	TWO SIGMA INVESTMENTS, LP	0.49%	236.28K	1.23M	114.3K	+93.71%
Mar 31, 2024	NANTAHALA CAPITAL MANAGEMENT, LLC	0.51%	243K	1.26M	43K	+21.50%
Mar 31, 2024	RENAISSANCE TECHNOLOGIES LLC	0.52%	246.41K	1.28M	-18.1K	-6.84%
Mar 31, 2024	GROUP ONE TRADING, L.P.	0.53%	254.03K	1.32M	203.75K	+405.21%
Mar 31, 2024	PFM HEALTH SCIENCES, LP	0.57%	274.54K	1.43M	274.54K	+100.00%
Mar 31, 2024	TWO SIGMA ADVISERS, LP	0.61%	289.5K	1.51M	261.2K	+922.97%
Mar 31, 2024	ADAR1 CAPITAL MANAGEMENT, LLC	0.61%	292.85K	1.52M	292.85K	+100.00%
Mar 31, 2024	VERITION FUND MANAGEMENT LLC	0.65%	310.57K	1.61M	7.13K	+2.35%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.66%	314.46K	1.64M	39.59K	+14.40%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.76%	362.33K	1.88M	-333.01K	-47.89%
Mar 31, 2024	BRIDGER MANAGEMENT, LLC	0.76%	362.35K	1.88M	0	0
Mar 31, 2024	ABRDN PLC	0.84%	400.48K	2.08M	0	0
Mar 31, 2024	IKARIAN CAPITAL, LLC	0.98%	469.13K	2.44M	311.77K	+198.12%
Mar 31, 2024	MILLENNIUM MANAGEMENT LLC	0.99%	474.58K	2.47M	19.11K	+4.20%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	1.01%	481.3K	2.5M	318.7K	+196.00%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	1.04%	499.82K	2.6M	20.15K	+4.20%
Mar 31, 2024	J. GOLDMAN & CO LP	1.07%	510.51K	2.65M	510.51K	+100.00%
Mar 31, 2024	VANGUARD GROUP INC	2.24%	1.07M	5.58M	109.74K	+11.40%
Mar 31, 2024	MORGAN STANLEY	3.17%	1.52M	7.89M	-241.59K	-13.73%
Mar 31, 2024	BLACKROCK INC.	3.89%	1.86M	9.68M	23.99K	+1.31%
Mar 31, 2024	GHOST TREE CAPITAL, LLC	0.34%	165K	858K	0	0
Mar 31, 2024	ALPHACENTRIC ADVISORS LLC	0.96%	460K	2.39M	38.98K	+9.26%
Mar 31, 2024	HUDSON BAY CAPITAL MANAGEMENT LP	1.1%	525K	2.73M	100K	+23.53%
Mar 31, 2024	CITADEL ADVISORS LLC	1.15%	550.57K	2.86M	379.52K	+221.89%
Mar 31, 2024	PRIVIUM FUND MANAGEMENT B.V.	1.21%	578.92K	3.01M	134.77K	+30.34%
Mar 31, 2024	JPMORGAN CHASE & CO	2.03%	969.5K	5.04M	220.15K	+29.38%
Dec 31, 2023	AMERIPRISE FINANCIAL INC	1.72%	820.26K	5.55M	445.8K	+119.05%
Dec 31, 2023	POINT72 ASSET MANAGEMENT, L.P.	1.95%	931.29K	6.3M	890.31K	+2,172.81%
Dec 31, 2023	VANGUARD GROUP INC	2.02%	962.8K	6.52M	9.36K	+0.98%
Dec 31, 2023	SCHRODER INVESTMENT MANAGEMENT GROUP	2.6%	1.24M	8.4M	1.24M	+100.00%
Dec 31, 2023		2.77%	1.32M	8.97M	320.55K	+31.94%
Dec 31, 2023	ORBIMED ADVISORS LLC	2.82%	1.35M	9.13M	-716.56K	-34.71%
Dec 31, 2023	683 CAPITAL MANAGEMENT, LLC	3.54%	1.69M	11.46M	118K	+7.49%
Dec 31, 2023	MORGAN STANLEY	3.68%	1.76M	11.91M	-921.59K	-34.37%
Dec 31, 2023	BLACKROCK INC.	3.84%	1.84M	12.43M	105.48K	+6.09%
Dec 31, 2023	STATE STREET CORP	7.28%	3.48M	23.55M	28.59K	+0.83%
Dec 31, 2023	SCHONFELD STRATEGIC ADVISORS LLC	0.26%	124.55K	843.2K	-258.08K	-67.45%
Dec 31, 2023	WALLEYE CAPITAL LLC	0.29%	140.76K	952.91K	14.78K	+11.73%
Dec 31, 2023	BANQUE PICTET & CIE SA	0.3%	144.59K	978.84K	-16.04K	-9.99%
Dec 31, 2023	BARCLAYS PLC	0.31%	149.47K	1.01M	-840.09K	-84.90%
Dec 31, 2023	NOMURA HOLDINGS INC	0.31%	150K	1.02M	150K	+100.00%
Dec 31, 2023	IKARIAN CAPITAL, LLC	0.33%	157.37K	1.07M	0	0
Dec 31, 2023	GHOST TREE CAPITAL, LLC	0.35%	165K	1.12M	-50K	-23.26%
Dec 31, 2023	UBS GROUP AG	0.35%	168K	1.14M	81.53K	+94.29%
Dec 31, 2023	CITADEL ADVISORS LLC	0.36%	171.04K	1.16M	-370.87K	-68.44%
Dec 31, 2023	ALGERT GLOBAL LLC	0.39%	188.21K	1.27M	-226.04K	-54.57%
Dec 31, 2023	CARLSON CAPITAL L P	0.41%	195K	1.32M	-100	-0.05%
Dec 31, 2023	NANTAHALA CAPITAL MANAGEMENT, LLC	0.42%	200K	1.35M	52.3K	+35.41%
Dec 31, 2023	NORGES BANK	0.43%	207.1K	1.4M	207.1K	+100.00%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.47%	222.39K	1.51M	-18.62K	-7.73%
Dec 31, 2023	SILVERCREST ASSET MANAGEMENT GROUP LLC	0.49%	235.21K	1.59M	-18.46K	-7.28%
Dec 31, 2023	ACADIAN ASSET MANAGEMENT LLC	0.55%	263.2K	1.78M	263.2K	+100.00%
Dec 31, 2023	RENAISSANCE TECHNOLOGIES LLC	0.55%	264.51K	1.79M	-184.6K	-41.10%
Dec 31, 2023	CUBIST SYSTEMATIC STRATEGIES, LLC	0.57%	274.45K	1.86M	77.29K	+39.20%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.58%	274.87K	1.86M	-79.16K	-22.36%
Dec 31, 2023	SECTORAL ASSET MANAGEMENT INC	0.61%	292.59K	1.98M	292.59K	+100.00%
Dec 31, 2023	VONTOBEL HOLDING LTD.	0.62%	295.04K	2M	242.21K	+458.50%
Dec 31, 2023	VERITION FUND MANAGEMENT LLC	0.64%	303.44K	2.05M	-340.21K	-52.86%
Dec 31, 2023	BRIDGER MANAGEMENT, LLC	0.76%	362.35K	2.45M	350.34K	+2,917.31%
Dec 31, 2023	RAFFERTY ASSET MANAGEMENT, LLC	0.77%	368.78K	2.5M	-22.06K	-5.64%
Dec 31, 2023	ABRDN PLC	0.84%	400.48K	2.71M	400.48K	+100.00%
Dec 31, 2023	ALPHACENTRIC ADVISORS LLC	0.88%	421.03K	2.85M	29.53K	+7.54%
Dec 31, 2023	HUDSON BAY CAPITAL MANAGEMENT LP	0.89%	425K	2.88M	34.8K	+8.92%
Dec 31, 2023	CAPTION MANAGEMENT, LLC	0.92%	441K	2.99M	381K	+635.00%
Dec 31, 2023	PRIVIUM FUND MANAGEMENT B.V.	0.93%	444.15K	3.08M	162.54K	+57.72%
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	0.95%	455.47K	3.08M	75.71K	+19.94%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	1%	479.68K	3.25M	31.44K	+7.01%
Dec 31, 2023	D. E. SHAW & CO., INC.	1.17%	560.33K	3.79M	148.6K	+36.09%
Dec 31, 2023	TANG CAPITAL MANAGEMENT LLC	1.26%	600K	4.06M	-335.8K	-35.88%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	1.46%	695.35K	4.71M	233.53K	+50.57%
Dec 31, 2023	MACQUARIE GROUP LTD	1.48%	706.17K	4.78M	0	0
Dec 31, 2023	BNP PARIBAS ARBITRAGE, SNC	1.48%	706.67K	4.78M	448.32K	+173.53%
Dec 31, 2023	CITIGROUP INC	1.56%	743.91K	5.04M	-22.61K	-2.95%
Dec 31, 2023	JPMORGAN CHASE & CO	1.57%	749.35K	5.07M	156.43K	+26.38%

Insiders

Insiders	Designation	Shares Held
KAPUSTA MATTHEW C	CEO, Managing Director	651.45K
KLEMT CHRISTIAN	Chief Financial Officer	217.73K
DOLMETSCH RICARDO	President, R&D	163.4K
ABI-SAAB WALID	Chief Medical Officer	150.44K
CALOZ PIERRE	Chief Operating Officer	115.71K
POTTS JEANNETTE	Chief Legal Officer	115.07K
KUTA ALEXANDER EDWARD III	Executive VP, Operations	90.38K
GUT ROBERT	director	40.15K
BALACHANDRAN MADHAVAN	director	37.7K
SPRINGHORN JEREMY P.	director	37.69K
MEEK DAVID D.	director	34.19K
POST LEONARD E	director	29.94K
JACQUES RACHELLE SUZANNE	director	28.35K
KAYE JACK	director	20.44K
SOTEROPOULOS PAULA	director	20.2K
ASTLEY-SPARKE PHILIP	director	9.95K

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Nov 06, 2025	GUT ROBERT	SALE	27.30	15.59K	425.72K	40.15K
Nov 04, 2025	KAYE JACK	SALE	30.33	17.81K	540.18K	20.44K
Sep 26, 2025	KLEMT CHRISTIAN	SALE	55.00	15K	825K	217.73K
Sep 24, 2025	KLEMT CHRISTIAN	SALE	40.04	3K	120.12K	217.73K
Sep 24, 2025	KAPUSTA MATTHEW C	SALE	45.10	60K	2.71M	651.45K
Jun 27, 2025	ABI-SAAB WALID	SALE	13.92	1.47K	20.41K	150.44K
Jun 20, 2025	BALACHANDRAN MADHAVAN	SALE	14.45	2.11K	30.52K	37.7K
Jun 20, 2025	POST LEONARD E	SALE	14.45	2.11K	30.52K	29.94K
Jun 20, 2025	SPRINGHORN JEREMY P.	SALE	14.45	2.11K	30.52K	37.69K
Jun 20, 2025	KAYE JACK	SALE	14.45	2.11K	30.52K	20.44K
Jun 20, 2025	JACQUES RACHELLE SUZANNE	SALE	14.45	2.11K	30.52K	28.35K
Jun 20, 2025	GUT ROBERT	SALE	14.45	3.34K	48.21K	56.88K
Jun 20, 2025	MEEK DAVID D.	SALE	14.45	2.11K	30.52K	34.19K
Jun 16, 2025	POTTS JEANNETTE	SALE	15.14	4.67K	70.7K	115.07K
Mar 04, 2025	KAPUSTA MATTHEW C	SALE	10.29	28.34K	291.63K	651.45K
Mar 04, 2025	ABI-SAAB WALID	SALE	10.29	1.35K	13.89K	151.9K
Mar 04, 2025	KLEMT CHRISTIAN	SALE	10.29	10.44K	107.41K	217.73K
Mar 04, 2025	POTTS JEANNETTE	SALE	10.29	7.08K	72.81K	119.74K
Feb 27, 2025	KAPUSTA MATTHEW C	SALE	11.32	6.72K	76.04K	580.8K
Feb 27, 2025	KLEMT CHRISTIAN	SALE	11.32	2.92K	33.01K	155.17K
Feb 25, 2025	KAPUSTA MATTHEW C	SALE	10.70	26.73K	285.98K	571.19K
Feb 25, 2025	KLEMT CHRISTIAN	SALE	10.70	14.34K	153.45K	152.37K
Dec 10, 2024	KAPUSTA MATTHEW C	SALE	15.03	100K	1.5M	597.92K
Dec 09, 2024	KAPUSTA MATTHEW C	SALE	7.63	3.42K	26.08K	597.92K
Dec 09, 2024	KLEMT CHRISTIAN	SALE	7.55	1.8K	13.56K	166.71K
Jun 26, 2024	ABI-SAAB WALID	SALE	4.36	1.45K	6.31K	115.25K
Jun 17, 2024	KLEMT CHRISTIAN	SALE	4.80	1.61K	7.73K	164.84K
Jun 17, 2024	CALOZ PIERRE	SALE	4.81	2.94K	14.12K	115.71K
Jun 13, 2024	BALACHANDRAN MADHAVAN	SALE	5.12	2.23K	11.42K	23.76K
Jun 13, 2024	POTTS JEANNETTE	SALE	4.98	4.78K	23.81K	91.82K
Jun 13, 2024	POST LEONARD E	SALE	5.14	2.22K	11.42K	16K
Jun 13, 2024	SPRINGHORN JEREMY P.	SALE	5.12	2.23K	11.42K	23.76K
Jun 13, 2024	GUT ROBERT	SALE	5.12	3.5K	17.94K	44.17K
Jun 13, 2024	KAYE JACK	SALE	5.16	2.22K	11.44K	6.5K
Jun 13, 2024	JACQUES RACHELLE SUZANNE	SALE	5.14	2.22K	11.42K	14.41K
Jun 13, 2024	SOTEROPOULOS PAULA	SALE	5.14	2.22K	11.41K	20.2K
Jun 13, 2024	MEEK DAVID D.	SALE	5.12	2.23K	11.41K	20.25K
Feb 26, 2024	KLEMT CHRISTIAN	SALE	6.38	15.91K	101.48K	116.95K
Feb 26, 2024	CALOZ PIERRE	SALE	6.47	9.46K	61.17K	85.64K
Feb 26, 2024	KAPUSTA MATTHEW C	SALE	6.35	27.9K	177.19K	440.84K
Sep 18, 2023	DOLMETSCH RICARDO	SALE	7.46	5.84K	43.57K	163.4K
Jul 10, 2023	CALOZ PIERRE	SALE	11.36	15.12K	171.73K	95.1K
Jun 16, 2023	SOTEROPOULOS PAULA	SALE	18.99	2.28K	43.2K	22.42K
Jun 16, 2023	KAYE JACK	SALE	18.93	2.28K	43.16K	34.12K
Jun 16, 2023	JACQUES RACHELLE SUZANNE	SALE	18.76	2.3K	43.17K	16.63K
Jun 16, 2023	CALOZ PIERRE	SALE	18.80	2.92K	54.9K	110.22K
Jun 16, 2023	GUT ROBERT	SALE	18.88	3.23K	60.94K	47.67K
Jun 16, 2023	MEEK DAVID D.	SALE	18.85	2.29K	43.17K	22.48K
Jun 16, 2023	POST LEONARD E	SALE	18.83	2.29K	43.14K	18.22K
Jun 16, 2023	BALACHANDRAN MADHAVAN	SALE	18.91	2.28K	43.17K	25.99K
Jun 16, 2023	SPRINGHORN JEREMY P.	SALE	18.88	2.29K	43.16K	25.99K
Jun 16, 2023	KLEMT CHRISTIAN	SALE	18.94	1.59K	30.06K	132.85K
Mar 07, 2023	KLEMT CHRISTIAN	SALE	21.36	986	21.06K	134.44K
Mar 07, 2023	DOLMETSCH RICARDO	SALE	21.04	837	17.61K	169.25K
Mar 07, 2023	KAPUSTA MATTHEW C	SALE	21.39	2.52K	53.92K	468.74K
Mar 07, 2023	CALOZ PIERRE	SALE	21.33	990	21.12K	113.14K
Mar 07, 2023	KUTA ALEXANDER EDWARD III	SALE	21.36	585	12.5K	90.38K
Feb 28, 2023	KAPUSTA MATTHEW C	SALE	20.90	5.02K	104.94K	471.26K
Feb 28, 2023	KLEMT CHRISTIAN	SALE	20.90	1.37K	28.61K	135.43K
Feb 28, 2023	KUTA ALEXANDER EDWARD III	SALE	21.04	1.21K	25.5K	90.97K
Feb 28, 2023	GUT ROBERT	SALE	21.16	1.43K	30.28K	42.2K
Feb 27, 2023	MEEK DAVID D.	SALE	19.71	389	7.67K	16.07K
Feb 27, 2023	POST LEONARD E	SALE	19.73	389	7.67K	11.81K
Feb 27, 2023	KLEMT CHRISTIAN	SALE	20.10	9.82K	197.46K	136.8K
Feb 27, 2023	KUTA ALEXANDER EDWARD III	SALE	19.99	5.51K	110.22K	92.18K
Feb 27, 2023	BALACHANDRAN MADHAVAN	SALE	19.99	384	7.68K	19.57K
Feb 27, 2023	SOTEROPOULOS PAULA	SALE	19.97	384	7.67K	16K
Feb 27, 2023	GUT ROBERT	SALE	19.79	537	10.63K	43.63K
Feb 27, 2023	KAYE JACK	SALE	19.99	384	7.68K	27.7K
Feb 27, 2023	JACQUES RACHELLE SUZANNE	SALE	20.02	384	7.69K	10.23K
Feb 27, 2023	SPRINGHORN JEREMY P.	SALE	20.41	384	7.84K	19.57K
Feb 27, 2023	DOLMETSCH RICARDO	SALE	19.58	6.94K	135.96K	170.08K
Feb 27, 2023	KAPUSTA MATTHEW C	SALE	20.24	1.39K	28.03K	476.29K
Feb 27, 2023	CALOZ PIERRE	SALE	20.80	81	1.68K	114.13K
Jan 18, 2023	SOTEROPOULOS PAULA	SALE	22.59	6K	135.54K	16.38K
Dec 14, 2022	SOTEROPOULOS PAULA	SALE	23.43	3.8K	89.03K	16.38K
Dec 09, 2022	KLEMT CHRISTIAN	SALE	22.35	2.61K	58.29K	107.18K
Dec 09, 2022	KUTA ALEXANDER EDWARD III	SALE	22.34	2.34K	52.23K	95.65K
Dec 09, 2022	KAPUSTA MATTHEW C	SALE	22.44	6.65K	149.18K	368.48K
Dec 09, 2022	DOLMETSCH RICARDO	SALE	22.30	2.22K	49.48K	127.41K
Dec 09, 2022	CALOZ PIERRE	SALE	22.22	2.94K	65.35K	68.87K
Nov 29, 2022	SOTEROPOULOS PAULA	SALE	25.38	6.2K	157.36K	16.38K
Sep 21, 2022	KUTA ALEXANDER EDWARD III	SALE	18.65	2.31K	43.01K	92.89K
Jul 28, 2022	KUTA ALEXANDER EDWARD III	SALE	25.01	406	10.15K	95.2K
Jul 27, 2022	KUTA ALEXANDER EDWARD III	SALE	25.00	10.4K	260.1K	95.2K
Jul 21, 2022	KUTA ALEXANDER EDWARD III	SALE	25.00	5.64K	141.08K	95.2K
Jun 16, 2022	KLEMT CHRISTIAN	SALE	13.20	1.69K	22.27K	104.69K
Jun 16, 2022	CALOZ PIERRE	SALE	13.21	7.58K	100.07K	64.51K
Feb 28, 2022	SOTEROPOULOS PAULA	SALE	16.87	596	10.05K	7.3K
Feb 28, 2022	GUT ROBERT	SALE	16.70	1.6K	26.75K	35.09K
Feb 28, 2022	KAYE JACK	SALE	16.76	600	10.06K	19K
Feb 28, 2022	POST LEONARD E	SALE	16.64	795	13.23K	3.12K
Feb 28, 2022	KAPUSTA MATTHEW C	SALE	16.70	10.2K	170.26K	360.55K
Feb 28, 2022	DOLMETSCH RICARDO	SALE	16.68	1.48K	24.75K	122.33K
Feb 28, 2022	KLEMT CHRISTIAN	SALE	16.80	4.08K	68.46K	106.38K
Feb 28, 2022	MEEK DAVID D.	SALE	16.70	602	10.05K	7.38K
Feb 28, 2022	KUTA ALEXANDER EDWARD III	SALE	16.72	3.41K	56.93K	95.16K
Feb 28, 2022	SPRINGHORN JEREMY P.	SALE	16.70	602	10.05K	10.88K
Feb 28, 2022	BALACHANDRAN MADHAVAN	SALE	16.70	602	10.05K	10.88K
Jan 26, 2022	KUTA ALEXANDER EDWARD III	SALE	18.02	2.95K	53.07K	63.7K
Jan 26, 2022	KAPUSTA MATTHEW C	SALE	18.10	10.9K	197.31K	245.68K
Jan 26, 2022	KLEMT CHRISTIAN	SALE	18.03	3.96K	71.45K	66.82K
Jan 26, 2022	GUT ROBERT	SALE	18.12	2.35K	42.55K	35.15K
Dec 15, 2021	KUTA ALEXANDER EDWARD III	SALE	27.90	6K	167.4K	66.64K
Nov 15, 2021	KUTA ALEXANDER EDWARD III	SALE	31.81	6K	190.86K	66.64K
Oct 15, 2021	KUTA ALEXANDER EDWARD III	SALE	30.65	6K	183.9K	66.64K
Sep 21, 2021	KLEMT CHRISTIAN	SALE	38.00	2.4K	91.2K	70.78K
Sep 21, 2021	GUT ROBERT	SALE	36.61	4.5K	164.75K	37.5K
Sep 21, 2021	KUTA ALEXANDER EDWARD III	SALE	36.71	2.23K	81.83K	66.64K
Sep 16, 2021	DOLMETSCH RICARDO	SALE	37.10	8.6K	319.17K	69.13K
Sep 15, 2021	KUTA ALEXANDER EDWARD III	SALE	36.32	6K	217.92K	68.87K
Aug 18, 2021	KAPUSTA MATTHEW C	SALE	28.64	117	3.35K	256.58K
Aug 16, 2021	KUTA ALEXANDER EDWARD III	SALE	28.84	6K	173.04K	68.87K
Jul 15, 2021	KUTA ALEXANDER EDWARD III	SALE	27.22	6K	163.32K	68.87K
Jul 14, 2021	KAPUSTA MATTHEW C	SALE	27.77	1K	27.77K	257.58K
Jun 17, 2021	KAPUSTA MATTHEW C	SALE	35.00	1.9K	66.5K	258.58K
Jun 16, 2021	KAPUSTA MATTHEW C	SALE	34.89	1.99K	69.54K	260.48K
Jun 15, 2021	KUTA ALEXANDER EDWARD III	SALE	35.43	6K	212.58K	68.87K
May 17, 2021	KUTA ALEXANDER EDWARD III	SALE	31.66	6K	189.96K	68.87K
May 12, 2021	KAPUSTA MATTHEW C	SALE	32.29	2.25K	72.65K	263.93K
Apr 15, 2021	KUTA ALEXANDER EDWARD III	SALE	35.06	6K	210.36K	68.87K
Apr 14, 2021	KAPUSTA MATTHEW C	SALE	35.07	3.63K	127.37K	267.9K
Mar 17, 2021	KAPUSTA MATTHEW C	SALE	34.54	6	207.24	271.53K
Mar 02, 2021	SOTEROPOULOS PAULA	SALE	37.60	504	18.95K	6.36K
Mar 02, 2021	MEEK DAVID D.	SALE	37.50	505	18.94K	6.45K
Mar 02, 2021	BALACHANDRAN MADHAVAN	SALE	37.50	505	18.94K	9.95K
Mar 02, 2021	ASTLEY-SPARKE PHILIP	SALE	37.60	504	18.95K	9.95K
Mar 02, 2021	KAYE JACK	SALE	37.60	504	18.95K	18.07K
Mar 02, 2021	GUT ROBERT	SALE	36.98	1.3K	48.07K	42K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES112.87K6

NET SHARES-112.87K6

SHARES HELD1.3M6

% NET SHARES-108.7%0%

QURE Stock Ownership Breakdown

uniQure NV

Stock Outstanding Shares

Market Insider

Institutional Ownership

Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions

Stock Outstanding Shares

Market Insider

Institutional Ownership

Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions