Stock Forecast Chart
Stock Price Prediction Summary
Forecast Score Based on 2 Weeks
Based on our forecast, the price of PYXS will decline by -81.10% over the next 2 Weeks and hit $0.21 by Tuesday, January 13, 2026. In that time frame, PYXS's share price is expected to range between $0.00 and $1.28.
BearishAverageBullishPYXS shares rose +5.50% in Wednesday, December 31, 2025's trading session, rising from a previous close of $1.09 to move at $1.15. The stock demonstrated notable intraday movement (see PYXS's key stats for a full breakdown), fluctuating between $1.09 and $1.20, a +10.60% trading range. While recent weeks have seen some volatility, PYXS has managed to secure a -71.25% drop over the past 2 weeks. The upward price movement was accompanied by decreased trading volume, with approximately 1.58M shares changing hands, 864.69K fewer than the previous session. This amounted to $1.81M in total market activity.
Will PYXS Continue Its Upward Trend?
According to analyst ratings and projections for PYXS, Pyxis Oncology, Inc. shares are anticipated to increase by +10.43%, potentially reaching $1.28 per share by January 13, 2026. Short-term technical indicators for PYXS currently suggest a bearish sentiment. This aligns with the stock's recent performance, as it has recorded 19 negative trading days within the past 30 sessions. Based on the PYXS stock forecast, now is a good time to buy PYXS stock because its current trading price is +458.25% above our predicted value, hinting at a possible undervaluation. For deeper insights, view our sentiment analysis on PYXS covering social and institutional perspectives.
PYXS Technical Momentum: Overbought, Oversold, or Neutral?
An analysis of Relative Strength Index (RSI) indicators provides insight into PYXS's momentum. Short-term RSIs (9, 14, and 20-day figures ranging from 16.54% to 27.82%) suggest the stock is in a strong bearish momentum phase. The 50-day RSI, at 40.05%, suggests a neutral medium-term outlook. Additionally, the 100-day RSI, at 45.03%, maintains a neutral outlook for the long term. Insights into PYXS's shareholder base show how institutional investors are positioning themselves during these momentum shifts
Pyxis Oncology Short-Term Forecasts
PYXS Forecast For Next 5 Days
Our algorithm anticipates Pyxis Oncology (PYXS) stock could hit $1.81 by Jan 07, 2026. This represents a +57.10% rise from today's price, following a +5.50% change over the past five days.
PYXS Forecast For Next 30 Days
Based on analysis of market trends, the outlook for Pyxis Oncology, Inc. (PYXS) stock over the next 30 days is largely positive. Price forecasts suggest an average target of $1.55, which would mean a +34.78% increase from the current price of $1.15. Projections for this period range from a high of $3.57 to a low of $0.00.
PYXS Forecast For Next 90 Days
Our proprietary market analysis suggests predictions for Pyxis Oncology's price over the next three months point to a rise. PYXS stock is expected to peak at $27.15 on Mar 31, 2026 after potentially dipping to $4.32 on Dec 31, 2025. On average, PYXS is likely to trade around $19.15 in the coming 90 days.
Pyxis Oncology Stock Forecast 2025
Based on our predictive models, Pyxis Oncology (PYXS) is expected to trade between $4.32 and $4.57 throughout 2025. This would result in an average price of $4.44, potentially offering investors a +286.09% return from current levels.
Pyxis Oncology, Inc. Monthly Forecast 2025–2026
December 2025
According to our latest forecast models, Pyxis Oncology, Inc. (PYXS) is positioned to show a strong performance in December 2025. The price is predicted to move between $4.32 and $4.57, settling at an average of $4.44. This could translate to a +286.09% gain.
January 2026
Based on current market signals, Pyxis Oncology, Inc. is projected to trend january 2026. We forecast a trading range from $4.37 to $17.33, with a likely average price of $10.62. Investors could expect a potential return of +823.48%.
February 2026
Our predictive algorithms indicate Pyxis Oncology, Inc. stock may see a shift in February 2026. The expected range spans $18.27–$26.44, with an average target of $23.16. This represents a positive outlook and a possible gain of +1,913.91%.
March 2026
Analyzing established trends, Pyxis Oncology, Inc. looks set to move in March 2026. Projections place the stock between $22.50 and $27.15, averaging around $24.71. This suggests a +2,048.70% gain from current levels.
April 2026
Market indicators suggest Pyxis Oncology, Inc. could experience notable changes during April 2026. Prices could fluctuate within $24.39 to $29.81, with a midpoint forecast of $27.30. The stock might deliver a +2,273.91% gain.
May 2026
Forecasting for May 2026, models estimate that Pyxis Oncology, Inc. may undergo key fluctuations. If trends hold, the stock might trade between $17.05 and $25.75, averaging $21.40. This signals a positive trajectory with potential returns around +1,760.87%.
June 2026
According to our latest forecast models, Pyxis Oncology, Inc. (PYXS) is positioned to show a strong performance in June 2026. The price is predicted to move between $13.82 and $17.00, settling at an average of $14.71. This could translate to a +1,179.13% gain.
July 2026
Based on current market signals, Pyxis Oncology, Inc. is projected to trend july 2026. We forecast a trading range from $15.77 to $20.14, with a likely average price of $16.92. Investors could expect a potential return of +1,371.30%.
August 2026
Our predictive algorithms indicate Pyxis Oncology, Inc. stock may see a shift in August 2026. The expected range spans $13.16–$19.71, with an average target of $15.31. This represents a positive outlook and a possible gain of +1,231.30%.
September 2026
Analyzing established trends, Pyxis Oncology, Inc. looks set to move in September 2026. Projections place the stock between $17.76 and $23.85, averaging around $19.59. This suggests a +1,603.48% gain from current levels.
October 2026
Market indicators suggest Pyxis Oncology, Inc. could experience notable changes during October 2026. Prices could fluctuate within $18.01 to $24.90, with a midpoint forecast of $19.96. The stock might deliver a +1,635.65% gain.
November 2026
Forecasting for November 2026, models estimate that Pyxis Oncology, Inc. may undergo key fluctuations. If trends hold, the stock might trade between $20.90 and $31.27, averaging $23.49. This signals a positive trajectory with potential returns around +1,942.61%.
December 2026
According to our latest forecast models, Pyxis Oncology, Inc. (PYXS) is positioned to show a strong performance in December 2026. The price is predicted to move between $10.20 and $26.47, settling at an average of $16.40. This could translate to a +1,326.09% gain.
PYXS's history of dividends and stock splits also plays a role in long-term investor confidence.

