How many institutions own OCUL stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own OCUL shares is 252, representing 90.81% of the company's common stock.

Who are the major shareholders selling Ocular Therapeutix, Inc. stock?

UBS GROUP AG, in the last quarter, reduced its stake in OCUL by -0.27% restricting it's holding to 1.24 million shares of worth nearly $15.11M. OCTAGON CAPITAL ADVISORS LP also lessened -0.02% of the OCUL shares from its portfolio, reducing its holding to 2.62 million shares of worth $31.85M. DEEP TRACK CAPITAL, LP also shunned OCUL shares holding by -32.36% last quarter which brought its holding to 8.07 million shares worth $97.97M.

Investors who are buying OCUL stock?

As per its latest 13F filing, SATURN V CAPITAL MANAGEMENT LLC increased its stake in OCUL by 30.67% in the last quarter. The institutional holder raised its holding to 1.5 million shares having worth more than $18.27M. WOODLINE PARTNERS LP also added 0% more shares of OCUL to its portfolio, raising its holding to 1.67 million shares of worth $20.23M. GEODE CAPITAL MANAGEMENT, LLC also increased its OCUL shares holding by 30.5% which brought its holding to 4.36 million shares worth $52.90M.

OCUL's major insiders: who are they?

The insider with the most stakes in OCUL is SUMMER ROAD LLC , 10 percent owner at the company. Additionally, OCUL stock is highly held by 10 percent owner Opaleye Management Inc. and See Remarks Dugel Pravin among others.

Did an insider recently sell OCUL stock?

Company executives, directors, and other insiders own 3.35% percent of Ocular Therapeutix, Inc.'s stock. Within the last six months, there have been 19 transaction(s) in which OCUL insiders have sold stock, totaling 282.26K shares. Insiders that have sold shares include KAISER PETER, HEIER JEFFREY S., and NAYAK SANJAY.

Which insider recently purchased OCUL stock?

There have been 1 transaction(s) during the past 6-months in which Ocular Therapeutix, Inc. insiders have bought stock, totalling 60229 shares

How much of OCUL does insiders own?

Around 13.89M Ocular Therapeutix, Inc. shares are held by insiders, which represents about 3.35% of OCUL stock.

Who is the insider with the largest stake?

OCUL 10 percent owner, SUMMER ROAD LLC holds the largest portfolio of the company's shares. OCUL shares owned by SUMMER total nearly 8.59 million.

Which institution holds the most shares in OCUL?

UBS GROUP AG is the largest institutional owner in OCUL which holds 1.24 million shares worth $15.11M or 0.66% of the total OCUL shares outstanding followed by SATURN V CAPITAL MANAGEMENT LLC with ownership of 1.5 million shares representing 0.8% of the OCUL ownership. OPALEYE MANAGEMENT INC. is the third largest stakeholder with 1.6 million shares or 0.85% of the ownership worth more than $19.36M.

Is Ocular Therapeutix, Inc. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the OCUL is concerned, it is a stock which is optionable.

Is there a short position on OCUL's shares?

Number of OCUL shares short is 12.83M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding OCUL shares are there?

As of today, 174.00M shares of OCUL are outstanding.

Is there many float in OCUL stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, OCUL has 145.32M shares in float.

OCUL short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for OCUL is 6.08.

Ocular Therapeutix (OCUL) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares7.42

Short Percent Of Float7.45

Shares Outstanding174.00M

Shares Float145.32M

Shares Short12.83M

Short Ratio6.08

7.45%

Short % of Float

7.42%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

3.35% Percentage of Shares held by All Insiders

90.81% Percentage of Shares held by All Institutions

93.96% Percentage of Float held by Institutions

252

Number of Institutions Holding Shares

Institutional Ownership

About 90.81% of OCUL shares are held by financial institutions. UBS GROUP AG is the top corporate investor, holding 1.24M shares valued at $15.11M. A 0.66% stake in Ocular Therapeutix, Inc. is owned by the company. SATURN V CAPITAL MANAGEMENT LLC owns 1.5M shares valued at $18.27M, which translates its holding of 0.8% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Dec 31, 2025	UBS GROUP AG	0.66%	1.24M	15.11M	-3.32K	-0.27%
Dec 31, 2025	SATURN V CAPITAL MANAGEMENT LLC	0.8%	1.5M	18.27M	353.19K	+30.67%
Dec 31, 2025	OPALEYE MANAGEMENT INC.	0.85%	1.6M	19.36M	0	0
Dec 31, 2025	WOODLINE PARTNERS LP	0.89%	1.67M	20.23M	49	0.00%
Dec 31, 2025	OCTAGON CAPITAL ADVISORS LP	1.4%	2.62M	31.85M	-400	-0.02%
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.33%	4.36M	52.9M	1.02M	+30.50%
Dec 31, 2025	DEEP TRACK CAPITAL, LP	4.31%	8.07M	97.97M	-3.86M	-32.36%
Dec 31, 2025	SUMMER ROAD LLC	5.93%	11.11M	134.86M	-1.47M	-11.69%
Dec 31, 2025	PARADIGM BIOCAPITAL ADVISORS LP	1.57%	2.94M	35.63M	-562.02K	-16.07%
Dec 31, 2025	MILLENNIUM MANAGEMENT LLC	1.71%	3.21M	38.94M	-647.83K	-16.80%
Dec 31, 2025	JANUS HENDERSON GROUP PLC	2.26%	4.23M	51.32M	2.18M	+106.45%
Dec 31, 2025	ALLIANCEBERNSTEIN L.P.	2.32%	4.34M	52.71M	917.51K	+26.79%
Dec 31, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	2.47%	4.63M	56.15M	620.7K	+15.50%
Dec 31, 2025	TCG CROSSOVER MANAGEMENT, LLC	3.07%	5.74M	69.69M	-377K	-6.16%
Dec 31, 2025	VR ADVISER, LLC	3.91%	7.32M	88.81M	-5.85M	-44.42%
Dec 31, 2025	AVORO CAPITAL ADVISORS LLC	5.76%	10.78M	130.84M	527.78K	+5.15%
Dec 31, 2025	VANGUARD GROUP INC	6.18%	11.58M	140.52M	2.41M	+26.32%
Dec 31, 2025	FMR LLC	16.98%	31.79M	385.88M	-29	0.00%
Dec 31, 2025	NEO IVY CAPITAL MANAGEMENT	0.09%	160.39K	1.95M	160.39K	+100.00%
Dec 31, 2025	SEI INVESTMENTS CO	0.09%	169.67K	2.06M	53.56K	+46.13%
Dec 31, 2025	VERITION FUND MANAGEMENT LLC	0.09%	171.61K	2.08M	5.57K	+3.36%
Dec 31, 2025	ROUNDANGLE ADVISORS LLC	0.09%	168.85K	2.05M	-7.95K	-4.49%
Dec 31, 2025	WALLEYE CAPITAL LLC	0.12%	230.51K	2.8M	169.67K	+278.87%
Dec 31, 2025	BLACKROCK, INC.	8.33%	15.6M	189.41M	5.05M	+47.79%
Dec 31, 2025	CAPTION MANAGEMENT, LLC	0.33%	615.1K	7.47M	565.1K	+1,130.20%
Dec 31, 2025	CATALIO CAPITAL MANAGEMENT, LP	0.38%	714.5K	8.67M	714.5K	+100.00%
Dec 31, 2025	CETERA INVESTMENT ADVISERS	0.39%	722.54K	8.77M	8.47K	+1.19%
Dec 31, 2025	BALYASNY ASSET MANAGEMENT L.P.	0.41%	763.56K	9.27M	-1.43M	-65.12%
Dec 31, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.41%	769.77K	9.35M	738.92K	+2,395.05%
Dec 31, 2025	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.43%	812.08K	9.86M	812.08K	+100.00%
Dec 31, 2025	RAYMOND JAMES FINANCIAL INC	0.45%	842.19K	10.22M	-169.78K	-16.78%
Dec 31, 2025	INVESCO LTD.	0.48%	895.69K	10.87M	-148.21K	-14.20%
Dec 31, 2025	POINT72 ASSET MANAGEMENT, L.P.	0.54%	1.02M	12.34M	-3.59M	-77.91%
Dec 31, 2025	JANE STREET GROUP, LLC	0.55%	1.03M	12.56M	680.42K	+192.31%
Dec 31, 2025	ACUTA CAPITAL PARTNERS, LLC	0.56%	1.05M	12.78M	-112.21K	-9.63%
Dec 31, 2025	ARTISAN PARTNERS LIMITED PARTNERSHIP	0.57%	1.06M	12.91M	-13.01K	-1.21%
Dec 31, 2025	SWISS NATIONAL BANK	0.17%	313.3K	3.8M	112.6K	+56.10%
Dec 31, 2025	CITADEL ADVISORS LLC	1.32%	2.48M	30.06M	-3.23M	-56.59%
Dec 31, 2025	TUDOR INVESTMENT CORP ET AL	0.2%	379.8K	4.61M	12.5K	+3.40%
Dec 31, 2025	TWO SIGMA INVESTMENTS, LP	0.2%	380.71K	4.62M	146.5K	+62.55%
Dec 31, 2025	CENTIVA CAPITAL, LP	0.2%	381.9K	4.64M	359K	+1,567.69%
Dec 31, 2025	ESSEX INVESTMENT MANAGEMENT CO LLC	0.21%	385.83K	4.68M	-8.25K	-2.09%
Dec 31, 2025	Y-INTERCEPT (HONG KONG) LTD	0.21%	395.34K	4.8M	395.34K	+100.00%
Dec 31, 2025	ROSALIND ADVISORS, INC.	0.21%	400K	4.86M	0	0
Dec 31, 2025	HRT FINANCIAL LP	0.22%	402.96K	4.89M	80.05K	+24.79%
Dec 31, 2025	SQUAREPOINT OPS LLC	0.24%	440.44K	5.35M	89.68K	+25.57%
Dec 31, 2025	BNP PARIBAS ASSET MANAGEMENT HOLDING S.A.	0.24%	445.41K	5.41M	444.41K	+44,845.01%
Dec 31, 2025	NUVEEN, LLC	0.25%	462.81K	5.62M	117.45K	+34.01%
Dec 31, 2025	PATIENT SQUARE CAPITAL LP	0.26%	490K	5.95M	-225K	-31.47%
Dec 31, 2025	BANK OF NEW YORK MELLON CORP	0.26%	490.28K	5.95M	89.51K	+22.33%
Dec 31, 2025	BANK OF AMERICA CORP /DE/	0.32%	601.36K	7.3B	154.24K	+34.50%
Dec 31, 2025	LOGOS GLOBAL MANAGEMENT LP	1.87%	3.5M	42.49M	250K	+7.69%
Dec 31, 2025	RHUMBLINE ADVISERS	0.13%	241.32K	2.93M	21.31K	+9.69%
Dec 31, 2025	WELLS FARGO & COMPANY/MN	0.14%	255.22K	3.1M	124.37K	+95.05%
Dec 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.14%	255.92K	3.11M	226.43K	+767.68%
Dec 31, 2025	RHENMAN & PARTNERS ASSET MANAGEMENT AB	0.14%	265K	3.22M	63K	+31.19%
Dec 31, 2025	FIRST TRUST ADVISORS LP	0.14%	268.69K	3.26M	-70.94K	-20.89%
Dec 31, 2025	JACOBS LEVY EQUITY MANAGEMENT, INC	0.16%	293.26K	3.56M	293.26K	+100.00%
Dec 31, 2025	APTUS CAPITAL ADVISORS, LLC	0.27%	500.75K	6.08M	98.29K	+24.42%
Dec 31, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.16%	307.75K	3.74M	106.49K	+52.91%
Dec 31, 2025	PRESCOTT GROUP CAPITAL MANAGEMENT, L.L.C.	0.17%	313K	3.8M	313K	+100.00%
Dec 31, 2025	MARSHALL WACE, LLP	0.74%	1.38M	16.72M	-224.25K	-14.00%
Dec 31, 2025	EMPIRE LIFE INVESTMENTS INC.	0.29%	540.12K	6.56M	288.85K	+114.96%
Dec 31, 2025	JPMORGAN CHASE & CO	0.29%	550.27K	6.68M	274.11K	+99.26%
Dec 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.78%	1.46M	17.73M	336.35K	+29.92%
Dec 31, 2025	GOLDMAN SACHS GROUP INC	0.83%	1.55M	18.79M	751.56K	+94.42%
Dec 31, 2025	DELTEC ASSET MANAGEMENT LLC	1.35%	2.49M	30.2M	-274.53K	-9.94%
Dec 31, 2025	STATE STREET CORP	2.24%	4.2M	50.94M	736.32K	+21.28%
Dec 31, 2025	PEREGRINE CAPITAL MANAGEMENT LLC	0.31%	571.1K	6.93M	-46.42K	-7.52%
Dec 31, 2025	DEUTSCHE BANK AG\	0.32%	590.72K	7.17M	278.64K	+89.28%
Dec 31, 2025	CITIGROUP INC	0.32%	601.92K	7.31M	-71.43K	-10.61%
Dec 31, 2025	ASSENAGON ASSET MANAGEMENT S.A.	0.34%	620.81K	7.54M	575.21K	+1,261.43%
Dec 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0.42%	791.2K	9.61M	791.2K	+100.00%
Dec 31, 2025		0.36%	681.66K	8.28B	681.66K	+100.00%
Dec 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.35%	653.7K	7.94M	113K	+20.90%
Dec 31, 2025	CANDRIAM S.C.A.	0.45%	841.6K	10.22M	841.6K	+100.00%
Dec 31, 2025	BARCLAYS PLC	0.46%	857.65K	10.41M	446.03K	+108.36%
Dec 31, 2025	MORGAN STANLEY	0.47%	879.14K	10.67M	-1.59M	-64.34%
Dec 31, 2025	D. E. SHAW & CO., INC.	0.62%	1.15M	14.01M	1.04M	+918.64%
Dec 31, 2025	NORTHERN TRUST CORP	0.78%	1.46M	17.75M	287.17K	+24.43%
Sep 30, 2025	GSA CAPITAL PARTNERS LLP	0.07%	115.55K	1.35M	115.55K	+100.00%
Sep 30, 2025	SEI INVESTMENTS CO	0.07%	116.11K	1.36M	-37.56K	-24.44%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0.08%	130.85K	1.53M	56.7K	+76.47%
Sep 30, 2025	COURIER CAPITAL LLC	0.08%	136.27K	1.59M	-18K	-11.67%
Sep 30, 2025	MACQUARIE GROUP LTD	0.1%	174.39K	2.04M	-67.65K	-27.95%
Sep 30, 2025	ROUNDANGLE ADVISORS LLC	0.1%	176.8K	2.07M	-8.91K	-4.80%
Sep 30, 2025	VOYA INVESTMENT MANAGEMENT LLC	0.11%	184.43K	2.16M	-107.14K	-36.75%
Sep 30, 2025	SWISS NATIONAL BANK	0.12%	200.7K	2.35M	3.3K	+1.67%
Sep 30, 2025	RHENMAN & PARTNERS ASSET MANAGEMENT AB	0.12%	202K	2.36M	202K	+100.00%
Sep 30, 2025	RHUMBLINE ADVISERS	0.13%	220.01K	2.57M	-5.54K	-2.46%
Sep 30, 2025	DRIEHAUS CAPITAL MANAGEMENT LLC	0.3%	518.75K	6.06M	518.75K	+100.00%
Sep 30, 2025	ERSTE ASSET MANAGEMENT GMBH	0.14%	235.8K	2.95M	0	0
Sep 30, 2025	AFFINITY ASSET ADVISORS, LLC	0.14%	239K	2.79M	239K	+100.00%
Sep 30, 2025	EMPIRE LIFE INVESTMENTS INC.	0.15%	251.26K	2.94M	251.26K	+100.00%
Sep 30, 2025	JPMORGAN CHASE & CO	0.16%	276.16K	3.23M	-435.94K	-61.22%
Sep 30, 2025	FMR LLC	18.42%	31.79M	371.57M	12.18M	+62.10%
Sep 30, 2025	RAYMOND JAMES FINANCIAL INC	0.59%	1.01M	11.83M	127.59K	+14.43%
Sep 30, 2025	AXA INVESTMENT MANAGERS S.A.	0.25%	439.88K	5.14M	439.88K	+100.00%
Sep 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	2.32%	4M	46.81M	114.17K	+2.93%
Sep 30, 2025	ROSALIND ADVISORS, INC.	0.23%	400K	4.68M	-818.7K	-67.18%
Sep 30, 2025	ROYAL BANK OF CANADA	0.23%	395.52K	4.62M	3.77K	+0.96%
Sep 30, 2025	ESSEX INVESTMENT MANAGEMENT CO LLC	0.23%	394.08K	4.61M	12.48K	+3.27%
Sep 30, 2025	TUDOR INVESTMENT CORP ET AL	0.21%	367.3K	4.29M	367.3K	+100.00%
Sep 30, 2025	STEMPOINT CAPITAL LP	0.21%	359.47K	4.2M	359.47K	+100.00%
Sep 30, 2025	JANE STREET GROUP, LLC	0.2%	353.81K	4.14B	243.34K	+220.27%
Sep 30, 2025	SQUAREPOINT OPS LLC	0.2%	350.76K	4.1M	350.76K	+100.00%
Sep 30, 2025	NUVEEN, LLC	0.2%	345.36K	4.04M	-16.95K	-4.68%
Sep 30, 2025	DEEP TRACK CAPITAL, LP	6.91%	11.93M	139.49M	-2.36M	-16.53%
Sep 30, 2025	PARADIGM BIOCAPITAL ADVISORS LP	2.03%	3.5M	40.88M	76.97K	+2.25%
Sep 30, 2025	DEUTSCHE BANK AG\	0.18%	312.08K	3.65M	72.06K	+30.02%
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.23%	400.77K	4.69M	18.46K	+4.83%
Sep 30, 2025	PEREGRINE CAPITAL MANAGEMENT LLC	0.36%	617.52K	7.22M	-244.44K	-28.36%
Sep 30, 2025	ACUTA CAPITAL PARTNERS, LLC	0.68%	1.17M	13.62M	150.27K	+14.81%
Sep 30, 2025	ALLIANCEBERNSTEIN L.P.	1.98%	3.42M	40.03M	3.26M	+2,003.21%
Sep 30, 2025	VR ADVISER, LLC	7.63%	13.16M	153.86M	399K	+3.13%
Sep 30, 2025	FIRST TRUST ADVISORS LP	0.2%	339.63K	3.97M	339.63K	+100.00%
Sep 30, 2025	AVORO CAPITAL ADVISORS LLC	5.94%	10.25M	119.82M	2.85M	+38.51%
Sep 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.31%	540.7K	6.32M	441.2K	+443.42%
Sep 30, 2025	INVESCO LTD.	0.6%	1.04M	12.2M	-494.95K	-32.16%
Sep 30, 2025	UBS GROUP AG	0.72%	1.25M	14.59M	-716.89K	-36.48%
Sep 30, 2025	APTUS CAPITAL ADVISORS, LLC	0.23%	402.47K	4.7M	17K	+4.41%
Sep 30, 2025	BARCLAYS PLC	0.24%	411.62K	4.81M	-84.41K	-17.02%
Sep 30, 2025	CITIGROUP INC	0.39%	673.35K	7.87M	573.5K	+574.40%
Sep 30, 2025	CETERA INVESTMENT ADVISERS	0.41%	714.07K	8.35M	8.66K	+1.23%
Sep 30, 2025	PATIENT SQUARE CAPITAL LP	0.41%	715K	8.36M	-102.7K	-12.56%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	0.46%	795.97K	9.3M	190.8K	+31.53%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.65%	1.12M	13.14M	28.65K	+2.62%
Sep 30, 2025	SATURN V CAPITAL MANAGEMENT LLC	0.67%	1.15M	13.46M	423.11K	+58.07%
Sep 30, 2025	MARSHALL WACE, LLP	0.93%	1.6M	18.72M	1.6M	+100.00%
Sep 30, 2025	DELTEC ASSET MANAGEMENT LLC	1.6%	2.76M	32.29M	-32.43K	-1.16%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.93%	3.34M	39.03M	54.28K	+1.65%
Sep 30, 2025	AMERIPRISE FINANCIAL INC	0.32%	555.15K	6.49M	322.26K	+138.38%
Sep 30, 2025	EVENTIDE ASSET MANAGEMENT, LLC	0.35%	598K	6.99M	598K	+100.00%
Sep 30, 2025	KNOLL CAPITAL MANAGEMENT, LLC	0.35%	600.4K	7.02M	0	0
Sep 30, 2025	ARTISAN PARTNERS LIMITED PARTNERSHIP	0.62%	1.08M	12.58M	10.41K	+0.98%
Sep 30, 2025	SECOND LINE CAPITAL, LLC	0.23%	402.47K	4.7M	17K	+4.41%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.26%	447.12K	5.23M	-312.14K	-41.11%
Sep 30, 2025	CUBIST SYSTEMATIC STRATEGIES, LLC	0.27%	466.18K	5.45M	466.18K	+100.00%
Sep 30, 2025	NORTHERN TRUST CORP	0.68%	1.18M	13.74M	19.08K	+1.65%
Sep 30, 2025	OPALEYE MANAGEMENT INC.	0.92%	1.6M	18.65M	0	0
Sep 30, 2025	WOODLINE PARTNERS LP	0.97%	1.67M	19.48M	915.14K	+121.86%
Sep 30, 2025	JANUS HENDERSON GROUP PLC	1.19%	2.05M	23.96M	2M	+3,728.97%
Sep 30, 2025	BALYASNY ASSET MANAGEMENT L.P.	1.27%	2.19M	25.59M	1.97M	+902.91%
Sep 30, 2025	MORGAN STANLEY	1.43%	2.47M	28.82M	-106.05K	-4.12%
Sep 30, 2025	OCTAGON CAPITAL ADVISORS LP	1.52%	2.62M	30.67M	199K	+8.21%
Sep 30, 2025	LOGOS GLOBAL MANAGEMENT LP	1.88%	3.25M	37.99M	1.05M	+47.73%
Sep 30, 2025	STATE STREET CORP	2%	3.46M	40.45M	-49.1K	-1.40%
Sep 30, 2025	MILLENNIUM MANAGEMENT LLC	2.23%	3.86M	45.07M	3.74M	+3,136.12%
Sep 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	2.67%	4.6M	53.79M	2.7M	+141.64%
Sep 30, 2025	CITADEL ADVISORS LLC	3.3%	5.7M	66.68M	817.77K	+16.74%
Sep 30, 2025	VANGUARD GROUP INC	5.31%	9.16M	107.12M	771.07K	+9.19%
Sep 30, 2025	BLACKROCK, INC.	6.12%	10.56M	123.41M	10.46K	+0.10%
Sep 30, 2025	SUMMER ROAD LLC	7.29%	12.58M	147.05M	-1.31M	-9.42%
Sep 30, 2025	TCG CROSSOVER MANAGEMENT, LLC	3.54%	6.12M	71.51M	798.08K	+15.00%
Sep 30, 2025	ASSENAGON ASSET MANAGEMENT S.A.	0.03%	45.6K	533.06K	-148.1K	-76.46%
Sep 30, 2025	HARBERT FUND ADVISORS, INC.	0.03%	50K	584.5K	50K	+100.00%
Sep 30, 2025	HUDSON BAY CAPITAL MANAGEMENT LP	0.03%	50.04K	584.96K	-4.05K	-7.49%
Sep 30, 2025	QUEST PARTNERS LLC	0.03%	50.6K	591.55K	30.41K	+150.56%
Sep 30, 2025	SG AMERICAS SECURITIES, LLC	0.03%	55.5K	649K	45.06K	+431.83%
Sep 30, 2025	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.04%	60.5K	707.23K	-1.5K	-2.41%
Sep 30, 2025	JUMP FINANCIAL, LLC	0.04%	62.22K	727.4K	62.22K	+100.00%
Sep 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.05%	78.42K	916.74K	-12.82K	-14.05%
Sep 30, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.05%	84.07K	982.73K	0	0
Sep 30, 2025	TRUIST FINANCIAL CORP	0.06%	100K	1.17M	0	0
Sep 30, 2025	DEKABANK DEUTSCHE GIROZENTRALE	0.06%	100K	1.24M	0	0
Sep 30, 2025	LEGAL & GENERAL GROUP PLC	0.06%	104.33K	1.22M	-525	-0.50%
Sep 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.06%	109.37K	1.28M	11.28K	+11.49%
Sep 30, 2025	LEGATO CAPITAL MANAGEMENT LLC	0.07%	112.82K	1.32M	0	0
Jun 30, 2025	OPALEYE MANAGEMENT INC.	0.92%	1.6M	14.8M	0	0
Jun 30, 2025	DEEP TRACK CAPITAL, LP	8.28%	14.29M	132.65M	0	0
Jun 30, 2025	BANCO SANTANDER, S.A.	0.11%	184.05K	1.71M	0	0
Jun 30, 2025	SUPERSTRING CAPITAL MANAGEMENT LP	0.05%	88.98K	825.73K	46.68K	+110.37%
Jun 30, 2025	HIGHVISTA STRATEGIES LLC	0.05%	88.88K	824.77K	3.64K	+4.26%
Jun 30, 2025	MIRAE ASSET GLOBAL ETFS HOLDINGS LTD.	0.04%	77.03K	714.88K	-16.59K	-17.72%
Jun 30, 2025	PARADIGM BIOCAPITAL ADVISORS LP	1.98%	3.42M	31.74M	2.11M	+160.30%
Jun 30, 2025	DELTEC ASSET MANAGEMENT LLC	1.62%	2.79M	25.94M	78.52K	+2.89%
Jun 30, 2025	CITADEL ADVISORS LLC	2.83%	4.89M	45.34M	74.91K	+1.56%
Jun 30, 2025	STATE STREET CORP	2.03%	3.51M	32.56M	117.26K	+3.46%
Jun 30, 2025	FMR LLC	11.36%	19.61M	181.96M	18.67M	+1,983.11%
Jun 30, 2025	SUMMER ROAD LLC	8.05%	13.89M	128.88M	9.45K	+0.07%
Jun 30, 2025	VR ADVISER, LLC	7.39%	12.76M	118.44M	0	0
Jun 30, 2025	PATIENT SQUARE CAPITAL LP	0.47%	817.7K	7.59M	-102.5K	-11.14%
Jun 30, 2025	ROYAL BANK OF CANADA	0.23%	391.75K	3.64M	389.05K	+14,361.20%
Jun 30, 2025	ESSEX INVESTMENT MANAGEMENT CO LLC	0.22%	381.6K	3.54M	-2.73K	-0.71%
Jun 30, 2025	CAPTION MANAGEMENT, LLC	0.13%	220.9K	2.05M	220.9K	+100.00%
Jun 30, 2025	IMC-CHICAGO, LLC	0.12%	207.77K	1.93M	207.77K	+100.00%
Jun 30, 2025	ASSENAGON ASSET MANAGEMENT S.A.	0.11%	193.7K	1.8M	-148.1K	-43.33%
Jun 30, 2025	WEISS ASSET MANAGEMENT LP	0.11%	187.62K	1.74M	187.62K	+100.00%
Jun 30, 2025	DARK FOREST CAPITAL MANAGEMENT LP	0.09%	161.9K	1.5M	161.9K	+100.00%
Jun 30, 2025	COURIER CAPITAL LLC	0.09%	154.27K	1.43M	0	0
Jun 30, 2025	VERITION FUND MANAGEMENT LLC	0.09%	148.6K	1.38M	78.17K	+110.99%
Jun 30, 2025	LEGATO CAPITAL MANAGEMENT LLC	0.07%	112.82K	1.05M	-270	-0.24%
Jun 30, 2025	DEKABANK DEUTSCHE GIROZENTRALE	0.06%	100K	918K	0	0
Jun 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.05%	91.24K	846.67K	-22.36K	-19.68%
Jun 30, 2025	BROWN ADVISORY INC	0.05%	90K	835.2K	0	0
Jun 30, 2025	D. E. SHAW & CO., INC.	0.06%	102.83K	954.29M	42.71K	+71.04%
Jun 30, 2025	MORGAN STANLEY	1.49%	2.57M	23.87M	383.25K	+17.51%
Jun 30, 2025	UBS GROUP AG	1.14%	1.97M	18.24M	630.21K	+47.21%
Jun 30, 2025	POINT72 ASSET MANAGEMENT, L.P.	1.1%	1.9M	17.67M	-38.15K	-1.96%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	1.04%	1.79M	16.6M	1.35M	+307.02%
Jun 30, 2025	INVESCO LTD.	0.89%	1.54M	14.28M	734.02K	+91.20%
Jun 30, 2025	ROSALIND ADVISORS, INC.	0.71%	1.22M	11.31M	0	0
Jun 30, 2025	FRANKLIN RESOURCES INC	0.68%	1.17M	10.86M	-96	-0.01%
Jun 30, 2025	NORTHERN TRUST CORP	0.67%	1.16M	10.73M	-134.66K	-10.43%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.63%	1.1M	10.17M	-17.34K	-1.56%
Jun 30, 2025	ARTISAN PARTNERS LIMITED PARTNERSHIP	0.62%	1.07M	9.89M	-89.11K	-7.71%
Jun 30, 2025	ACUTA CAPITAL PARTNERS, LLC	0.59%	1.01M	9.42M	-204.78K	-16.79%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.35%	605.17K	5.62M	23.16K	+3.98%
Jun 30, 2025	AXA S.A.	0.3%	516.5K	4.79M	-43.02K	-7.69%
Jun 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.29%	503.99K	4.68M	51.02K	+11.26%
Jun 30, 2025	BARCLAYS PLC	0.29%	496.03K	4.6M	794	+0.16%
Jun 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.24%	410.05K	3.81M	-43.95K	-9.68%
Jun 30, 2025	BANK OF NEW YORK MELLON CORP	0.22%	382.31K	3.55M	-37.18K	-8.86%
Jun 30, 2025	ALLIANCEBERNSTEIN L.P.	0.09%	162.82K	1.51B	0	0
Jun 30, 2025	STATE OF WISCONSIN INVESTMENT BOARD	0.07%	126.68K	1.18M	-72.35K	-36.35%
Jun 30, 2025	TCG CROSSOVER MANAGEMENT, LLC	3.08%	5.32M	49.36M	0	0
Jun 30, 2025	PEREGRINE CAPITAL MANAGEMENT LLC	0.5%	861.96K	8M	14.49K	+1.71%
Jun 30, 2025	CETERA INVESTMENT ADVISERS	0.41%	705.41K	6.55M	-15.96K	-2.21%
Jun 30, 2025	BALYASNY ASSET MANAGEMENT L.P.	0.13%	218.29K	2.03M	142.42K	+187.72%
Jun 30, 2025	UBS OCONNOR LLC	0.07%	120K	153K	0	0
Jun 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.12%	208.53K	1.94B	154.05K	+282.74%
Jun 30, 2025	AQR CAPITAL MANAGEMENT LLC	0.06%	111.02K	1.03B	95.37K	+609.41%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.9%	3.28M	30.48M	-138.24K	-4.04%
Jun 30, 2025	OCTAGON CAPITAL ADVISORS LP	1.41%	2.43M	22.5M	0	0
Jun 30, 2025	LOGOS GLOBAL MANAGEMENT LP	1.27%	2.2M	20.42M	-100K	-4.35%
Jun 30, 2025	RAYMOND JAMES FINANCIAL INC	0.51%	884.38K	8.21M	520.14K	+142.80%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0.44%	759.26K	7.05M	-183.03K	-19.42%
Jun 30, 2025	WOODLINE PARTNERS LP	0.44%	750.95K	6.97M	0	0
Jun 30, 2025	SATURN V CAPITAL MANAGEMENT LLC	0.42%	728.58K	6.76M	130.39K	+21.80%
Jun 30, 2025	JPMORGAN CHASE & CO	0.41%	712.1K	6.61M	374.27K	+110.79%
Jun 30, 2025	KNOLL CAPITAL MANAGEMENT, LLC	0.35%	600.4K	1.86M	0	0
Jun 30, 2025	PALE FIRE CAPITAL SE	0.31%	530.14K	4.92M	90.75K	+20.65%
Jun 30, 2025	APTUS CAPITAL ADVISORS, LLC	0.22%	385.47K	3.58M	39.37K	+11.38%
Jun 30, 2025	UBS ASSET MANAGEMENT AMERICAS INC	0.18%	316.28K	2.94M	103.32K	+48.52%
Jun 30, 2025	BLACKROCK, INC.	6.11%	10.55M	97.87M	-1.47M	-12.20%
Jun 30, 2025	AVORO CAPITAL ADVISORS LLC	4.29%	7.4M	68.67M	-660K	-8.19%
Jun 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	2.25%	3.89M	36.1M	-1.31M	-25.19%
Jun 30, 2025	SECOND LINE CAPITAL, LLC	0.22%	385.47K	3.58M	39.37K	+11.38%
Jun 30, 2025		0.21%	362.31K	3.36M	-51.79K	-12.51%
Jun 30, 2025	VANGUARD GROUP INC	4.86%	8.39M	77.88M	27.66K	+0.33%
Jun 30, 2025	NUVEEN, LLC	0.21%	362.31K	3.36M	-51.79K	-12.51%
Mar 31, 2025	SUMMER ROAD LLC	8.19%	13.88M	101.73M	8.55K	+0.06%
Mar 31, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.27%	452.96K	3.32M	-14.39K	-3.08%
Mar 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0.27%	454K	3.33M	454K	+100.00%
Mar 31, 2025	TWO SIGMA INVESTMENTS, LP	0.27%	461.23K	3.38M	208.29K	+82.35%
Mar 31, 2025	SILVERARC CAPITAL MANAGEMENT, LLC	0.33%	551.57K	4.04M	551.57K	+100.00%
Mar 31, 2025	INVESCO LTD.	0.48%	804.83K	5.9M	-85.22K	-9.57%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0.56%	942.29K	6.91M	505.22K	+115.59%
Mar 31, 2025	VR ADVISER, LLC	7.53%	12.76M	93.55M	0	0
Mar 31, 2025	BARCLAYS PLC	0.29%	495.24K	3.63M	163.99K	+49.51%
Mar 31, 2025	PEREGRINE CAPITAL MANAGEMENT LLC	0.5%	847.47K	6.21M	847.47K	+100.00%
Mar 31, 2025	AXA S.A.	0.33%	559.52K	4.1M	-78.31K	-12.28%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.34%	582.01K	4.27M	-90.61K	-13.47%
Mar 31, 2025	DEEP TRACK CAPITAL, LP	8.44%	14.29M	104.78M	1.46M	+11.36%
Mar 31, 2025	PERCEPTIVE ADVISORS LLC	0.54%	915.78K	6.71M	-162.72K	-15.09%
Mar 31, 2025	PATIENT SQUARE CAPITAL LP	0.54%	920.2K	6.75M	449.28K	+95.40%
Mar 31, 2025	ROSALIND ADVISORS, INC.	0.72%	1.22M	8.93M	90K	+7.97%
Mar 31, 2025	MORGAN STANLEY	1.29%	2.19M	16.04M	365.55K	+20.05%
Mar 31, 2025	ASSENAGON ASSET MANAGEMENT S.A.	0.2%	341.8K	2.51M	341.8K	+100.00%
Mar 31, 2025	SECOND LINE CAPITAL, LLC	0.2%	346.1K	2.54M	6K	+1.76%
Mar 31, 2025	SATURN V CAPITAL MANAGEMENT LLC	0.35%	598.19K	4.38M	406.74K	+212.44%
Mar 31, 2025	KNOLL CAPITAL MANAGEMENT, LLC	0.35%	600.4K	4.4M	0	0
Mar 31, 2025	FRANKLIN RESOURCES INC	0.69%	1.17M	8.58M	3	0.00%
Mar 31, 2025	ACUTA CAPITAL PARTNERS, LLC	0.72%	1.22M	8.94M	108.65K	+9.78%
Mar 31, 2025	NORTHERN TRUST CORP	0.76%	1.29M	9.46M	-23.95K	-1.82%
Mar 31, 2025	PARADIGM BIOCAPITAL ADVISORS LP	0.78%	1.31M	9.63M	1.31M	+100.00%
Mar 31, 2025	UBS GROUP AG	0.79%	1.33M	9.79M	458.39K	+52.30%
Mar 31, 2025	OPALEYE MANAGEMENT INC.	0.94%	1.6M	11.69M	-2.75M	-63.27%
Mar 31, 2025	POINT72 ASSET MANAGEMENT, L.P.	1.15%	1.94M	14.24M	-993.56K	-33.84%
Mar 31, 2025	OCTAGON CAPITAL ADVISORS LP	1.43%	2.43M	17.78M	0	0
Mar 31, 2025	CITADEL ADVISORS LLC	2.84%	4.81M	35.27M	354.3K	+7.95%
Mar 31, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	3.07%	5.2M	38.12M	1.6M	+44.44%
Mar 31, 2025	TCG CROSSOVER MANAGEMENT, LLC	3.14%	5.32M	38.99M	0	0
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.02%	3.42M	25.09M	186.1K	+5.75%
Mar 31, 2025	AVORO CAPITAL ADVISORS LLC	4.76%	8.06M	59.08M	0	0
Mar 31, 2025	VANGUARD GROUP INC	4.94%	8.36M	61.31M	-119.4K	-1.41%
Mar 31, 2025	BLACKROCK, INC.	7.09%	12.01M	88.05M	165.91K	+1.40%
Mar 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.26%	439.44K	3.22M	327.71K	+293.28%
Mar 31, 2025	FMR LLC	0.56%	941.29K	6.9M	480.85K	+104.43%
Mar 31, 2025	APTUS CAPITAL ADVISORS, LLC	0.2%	346.1K	2.54M	6.35K	+1.87%
Mar 31, 2025		0.24%	414.1K	3.04M	414.1K	+100.00%
Mar 31, 2025	RAYMOND JAMES FINANCIAL INC	0.22%	364.24K	2.67M	162.62K	+80.66%
Mar 31, 2025	ESSEX INVESTMENT MANAGEMENT CO LLC	0.23%	384.33K	2.82M	-2.92K	-0.75%
Mar 31, 2025	PALE FIRE CAPITAL SE	0.26%	439.39K	3.22M	-5.43K	-1.22%
Mar 31, 2025	BANK OF NEW YORK MELLON CORP	0.25%	419.49K	3.07M	-738	-0.18%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.66%	1.11M	8.16M	-18.69K	-1.65%
Mar 31, 2025	DELTEC ASSET MANAGEMENT LLC	1.6%	2.72M	19.91M	100K	+3.82%
Mar 31, 2025	STATE STREET CORP	2%	3.39M	24.86M	-98.04K	-2.81%
Mar 31, 2025	ARTISAN PARTNERS LIMITED PARTNERSHIP	0.68%	1.16M	8.47M	-179.63K	-13.46%
Mar 31, 2025	CETERA INVESTMENT ADVISERS	0.43%	721.36K	5.29M	-2.48K	-0.34%
Mar 31, 2025	WOODLINE PARTNERS LP	0.44%	750.95K	5.5M	-251.49K	-25.09%
Mar 31, 2024	SIMPLEX TRADING, LLC	0.04%	33.84K	307K	-25.27K	-42.75%
Mar 31, 2024	WELLS FARGO & COMPANY/MN	0.04%	36.04K	327.96K	13.84K	+62.32%
Mar 31, 2024	BALBOA WEALTH PARTNERS	0.05%	38K	345.8K	38K	+100.00%
Mar 31, 2024	SEMANTEON CAPITAL MANAGEMENT, LP	0.05%	39.12K	356.01K	39.12K	+100.00%
Mar 31, 2024	JUMP FINANCIAL, LLC	0.05%	43.32K	394.2K	43.32K	+100.00%
Mar 31, 2024	NEW YORK STATE COMMON RETIREMENT FUND	0.05%	46.35K	422K	14.92K	+47.49%
Mar 31, 2024	QUANTBOT TECHNOLOGIES LP	0.06%	46.5K	423.15K	46.5K	+100.00%
Mar 31, 2024	MIRAE ASSET GLOBAL INVESTMENTS CO., LTD.	0.06%	53.46K	284.21K	53.46K	+100.00%
Mar 31, 2024	RAYMOND JAMES FINANCIAL SERVICES ADVISORS, INC.	0.06%	54.18K	493.07K	-7.86K	-12.66%
Mar 31, 2024	STATE OF WISCONSIN INVESTMENT BOARD	0.07%	55.2K	502.32K	55.2K	+100.00%
Mar 31, 2024	AMERICAN INTERNATIONAL GROUP, INC.	0.07%	56.98K	518.53K	17.25K	+43.42%
Mar 31, 2024	LINCOLN NATIONAL CORP	0.07%	57.23K	520.76K	0	0
Mar 31, 2024	METLIFE INVESTMENT MANAGEMENT, LLC	0.07%	59.33K	539.93K	18.69K	+45.97%
Mar 31, 2024	FMR LLC	0.08%	69.09K	628.74K	-28	-0.04%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.09%	72.44K	659.2K	40.7K	+128.25%
Mar 31, 2024	TD ASSET MANAGEMENT INC	0.1%	80.4K	731.64M	80.4K	+100.00%
Mar 31, 2024	BROWN ADVISORY INC	0.11%	90K	819K	0	0
Mar 31, 2024	DEKABANK DEUTSCHE GIROZENTRALE	0.12%	100K	892K	0	0
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	0.12%	104.95K	955.05K	10.6K	+11.23%
Mar 31, 2024	RATAN CAPITAL MANAGEMENT LP	0.14%	115K	1.05M	115K	+100.00%
Mar 31, 2024	CITIGROUP INC	0.14%	118.31K	1.08M	99.13K	+516.91%
Mar 31, 2024	LEGATO CAPITAL MANAGEMENT LLC	0.18%	149.52K	1.36M	0	0
Mar 31, 2024	RHUMBLINE ADVISERS	0.18%	151.96K	1.38M	37.99K	+33.34%
Mar 31, 2024	BNP PARIBAS ARBITRAGE, SNC	0.22%	185.31K	1.69M	146.14K	+373.09%
Mar 31, 2024	ESSEX INVESTMENT MANAGEMENT CO LLC	0.45%	376.2K	3.42M	5.83K	+1.57%
Mar 31, 2024	AVORO CAPITAL ADVISORS LLC	8.47%	7.15M	65.06M	7.15M	+100.00%
Mar 31, 2024	VANGUARD GROUP INC	8.57%	7.24M	65.84M	2.12M	+41.36%
Mar 31, 2024	DEEP TRACK CAPITAL, LP	15.07%	12.72M	115.77M	3.49M	+37.82%
Mar 31, 2024	BLACKROCK INC.	9.55%	8.06M	73.38M	2.3M	+39.96%
Mar 31, 2024	JPMORGAN CHASE & CO	0.08%	69.23K	629.96K	1.2K	+1.77%
Mar 31, 2024	UBS OCONNOR LLC	0.22%	188.58K	1.72M	-143.51K	-43.22%
Mar 31, 2024	NOTTINGHAM ADVISORS, INC.	0.23%	193.27K	1.76M	-1K	-0.51%
Mar 31, 2024	EXOME ASSET MANAGEMENT LLC	0.23%	193.6K	1.76M	193.6K	+100.00%
Mar 31, 2024	RAYMOND JAMES & ASSOCIATES	0.23%	195.03K	1.77M	66.02K	+51.17%
Mar 31, 2024	KNOLL CAPITAL MANAGEMENT, LLC	0.24%	200.4K	1.82M	0	0
Mar 31, 2024	BANCO SANTANDER, S.A.	0.25%	208.2K	1.89M	-332.28K	-61.48%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.27%	227.05K	2.07M	140.06K	+161.01%
Mar 31, 2024	JANE STREET GROUP, LLC	0.3%	252.36K	2.3M	121.25K	+92.48%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.32%	269.18K	2.45M	181.63K	+207.45%
Mar 31, 2024	WELLINGTON MANAGEMENT GROUP LLP	0.32%	270.92K	2.47M	270.92K	+100.00%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.37%	313.04K	2.85M	91.83K	+41.52%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.23%	195.52K	1.78M	87.87K	+81.63%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.39%	331.25K	3.01M	87.89K	+36.12%
Mar 31, 2024	CUBIST SYSTEMATIC STRATEGIES, LLC	0.4%	336.13K	3.06M	336.13K	+100.00%
Mar 31, 2024	BARCLAYS PLC	0.43%	361.09K	3.29M	250.99K	+227.95%
Mar 31, 2024	GROUP ONE TRADING, L.P.	0.44%	373.3K	3.4M	328.9K	+740.79%
Mar 31, 2024	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.44%	375K	3.41M	375K	+100.00%
Mar 31, 2024	SIO CAPITAL MANAGEMENT, LLC	0.45%	383.03K	3.49M	-588.42K	-60.57%
Mar 31, 2024	UBS GROUP AG	0.57%	483.51K	4.4M	392.67K	+432.30%
Mar 31, 2024	AXA S.A.	0.76%	638.31K	5.81M	179	+0.03%
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	0.78%	662.67K	6.03M	609.33K	+1,142.26%
Mar 31, 2024	CETERA ADVISORS LLC	0.86%	723.49K	6.58M	676.96K	+1,454.99%
Mar 31, 2024	ARTIA GLOBAL PARTNERS LP	0.86%	724.69K	6.59M	284.69K	+64.70%
Mar 31, 2024	CETERA INVESTMENT ADVISERS	0.86%	725.99K	6.61M	49.59K	+7.33%
Mar 31, 2024	INVESCO LTD.	0.91%	772.37K	7.03M	551.34K	+249.44%
Mar 31, 2024	DEUTSCHE BANK AG\	0.94%	797.53K	7.26M	762.89K	+2,202.40%
Mar 31, 2024	NORTHERN TRUST CORP	1.15%	970.1K	8.83M	298.11K	+44.36%
Mar 31, 2024	VOLORIDGE INVESTMENT MANAGEMENT, LLC	1.29%	1.09M	9.89M	1.09M	+100.00%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	1.44%	1.21M	11.04M	200.9K	+19.84%
Mar 31, 2024	MORGAN STANLEY	1.63%	1.37M	12.49M	1.05M	+324.88%
Mar 31, 2024	GREAT POINT PARTNERS LLC	2.05%	1.73M	15.73M	1.03M	+146.96%
Mar 31, 2024	FRANKLIN RESOURCES INC	2.57%	2.17M	19.73M	-2.33M	-51.82%
Mar 31, 2024	DELTEC ASSET MANAGEMENT LLC	2.8%	2.36M	21.51M	-79.52K	-3.25%
Mar 31, 2024	STATE STREET CORP	2.85%	2.4M	21.86M	862.81K	+56.04%
Mar 31, 2024	OCTAGON CAPITAL ADVISORS LP	2.87%	2.43M	22.07M	2.43M	+100.00%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	2.94%	2.49M	22.63M	749.23K	+43.14%
Mar 31, 2024	ACUTA CAPITAL PARTNERS, LLC	3.12%	2.64M	23.98M	1.33M	+101.17%
Mar 31, 2024	PERCEPTIVE ADVISORS LLC	3.94%	3.32M	30.25M	3.32M	+100.00%
Mar 31, 2024	TCG CROSSOVER MANAGEMENT, LLC	6.3%	5.32M	48.4M	5.32M	+100.00%
Mar 31, 2024	LOGOS GLOBAL MANAGEMENT LP	6.88%	5.81M	51.99M	1.81M	+45.29%
Mar 31, 2024	OPALEYE MANAGEMENT INC.	7.88%	6.65M	60.54M	583.14K	+9.61%
Mar 31, 2024	SUMMER ROAD LLC	17.01%	14.36M	130.68M	6.7M	+87.46%
Mar 31, 2024	CITADEL ADVISORS LLC	6.42%	5.42M	48.42M	1.88M	+53.30%
Mar 31, 2024	VR ADVISER, LLC	15.12%	12.76M	116.14M	4.99M	+64.13%
Mar 31, 2024	SG AMERICAS SECURITIES, LLC	0.03%	28.95K	263K	9.3K	+47.34%
Mar 31, 2024	SIMPLICITY WEALTH,LLC	0.03%	28.99K	263.78K	28.99K	+100.00%
Mar 31, 2024	RENAISSANCE TECHNOLOGIES LLC	0.04%	29.7K	270K	29.7K	+100.00%
Mar 31, 2024	IEQ CAPITAL, LLC	0.04%	30.13K	274.17K	0	0
Mar 31, 2024	STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM	0.04%	31.28K	164.84K	-140	-0.45%
Dec 31, 2023		0.33%	279.65K	1.25M	279.65K	+100.00%
Dec 31, 2023	JPMORGAN CHASE & CO	0.08%	68.03K	303.39K	148	+0.22%
Dec 31, 2023	FMR LLC	0.08%	69.12K	308.28K	340	+0.49%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.1%	86.99K	387.97K	29.92K	+52.44%
Dec 31, 2023	MORGAN STANLEY	0.38%	323.16K	1.44M	76.73K	+31.14%
Dec 31, 2023	DEEP TRACK CAPITAL, LP	10.84%	9.23M	41.17M	9.23M	+100.00%
Dec 31, 2023	VR ADVISER, LLC	9.13%	7.78M	34.68M	7.78M	+100.00%
Dec 31, 2023	SUMMER ROAD LLC	9%	7.66M	34.17M	1.54M	+25.13%
Dec 31, 2023	OPALEYE MANAGEMENT INC.	7.13%	6.07M	27.07M	-398K	-6.15%
Dec 31, 2023	BLACKROCK INC.	6.77%	5.76M	25.7M	417.98K	+7.82%
Dec 31, 2023	VANGUARD GROUP INC	6.01%	5.12M	22.83M	1.06M	+26.03%
Dec 31, 2023	FRANKLIN RESOURCES INC	5.29%	4.5M	20.07M	4.5M	+100.00%
Dec 31, 2023	LOGOS GLOBAL MANAGEMENT LP	4.7%	4M	17.84M	4M	+100.00%
Dec 31, 2023	CITADEL ADVISORS LLC	4.15%	3.54M	15.77M	2.25M	+174.25%
Dec 31, 2023	DELTEC ASSET MANAGEMENT LLC	2.87%	2.44M	10.9M	381.81K	+18.52%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	2.04%	1.74M	7.75M	107.29K	+6.58%
Dec 31, 2023	STATE STREET CORP	1.81%	1.54M	6.87M	-242.29K	-13.60%
Dec 31, 2023	ACUTA CAPITAL PARTNERS, LLC	1.54%	1.31M	5.84M	1.31M	+100.00%
Dec 31, 2023	NUVEEN ASSET MANAGEMENT, LLC	1.19%	1.01M	4.52M	1.51K	+0.15%
Dec 31, 2023	SIO CAPITAL MANAGEMENT, LLC	1.14%	971.45K	4.33M	971.45K	+100.00%
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	0.91%	775.17K	3.46M	89.43K	+13.04%
Dec 31, 2023	GREAT POINT PARTNERS LLC	0.82%	700K	3.12M	700K	+100.00%
Dec 31, 2023	CETERA INVESTMENT ADVISERS	0.79%	676.4K	3.02M	66.3K	+10.87%
Dec 31, 2023	NORTHERN TRUST CORP	0.79%	671.98K	3M	-1.75K	-0.26%
Dec 31, 2023	AXA S.A.	0.75%	638.13K	2.85M	-1.11K	-0.17%
Dec 31, 2023	BANCO SANTANDER, S.A.	0.63%	540.48K	2.41M	143.03K	+35.99%
Dec 31, 2023	ARTIA GLOBAL PARTNERS LP	0.52%	440K	1.96M	440K	+100.00%
Dec 31, 2023	D. E. SHAW & CO., INC.	0.46%	390.84K	1.74M	-194.05K	-33.18%
Dec 31, 2023	ESSEX INVESTMENT MANAGEMENT CO LLC	0.44%	370.37K	1.65M	370.37K	+100.00%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.1%	87.55K	390.49K	-27.83K	-24.12%
Dec 31, 2023	UBS OCONNOR LLC	0.39%	332.09K	1.48M	-10.02K	-2.93%
Dec 31, 2023	BALYASNY ASSET MANAGEMENT L.P.	0.1%	89K	396.94K	36.66K	+70.03%
Dec 31, 2023	BROWN ADVISORY INC	0.11%	90K	401.4K	0	0
Dec 31, 2023	UBS GROUP AG	0.11%	90.83K	405.12K	37.26K	+69.55%
Dec 31, 2023	ALLIANCEBERNSTEIN L.P.	0.11%	94.35K	420.8K	0	0
Dec 31, 2023	DEKABANK DEUTSCHE GIROZENTRALE	0.12%	100K	461K	0	0
Dec 31, 2023	BARCLAYS PLC	0.13%	110.11K	491K	84.14K	+324.09%
Dec 31, 2023	TWO SIGMA INVESTMENTS, LP	0.13%	111K	495.06K	-5.1K	-4.39%
Dec 31, 2023	RHUMBLINE ADVISERS	0.13%	113.97K	508.28K	-16.05K	-12.35%
Dec 31, 2023	RAYMOND JAMES & ASSOCIATES	0.15%	129.01K	575.39K	8.45K	+7.01%
Dec 31, 2023	JANE STREET GROUP, LLC	0.15%	131.11K	584.73K	70.74K	+117.19%
Dec 31, 2023	TUDOR INVESTMENT CORP ET AL	0.16%	138.73K	618.74K	-35.44K	-20.35%
Dec 31, 2023	LEGATO CAPITAL MANAGEMENT LLC	0.18%	149.52K	666.84K	149.52K	+100.00%
Dec 31, 2023	PARADIGM CAPITAL MANAGEMENT INC/NY	0.19%	160K	713.6K	80K	+100.00%
Dec 31, 2023	NOTTINGHAM ADVISORS, INC.	0.23%	194.27K	866.43K	0	0
Dec 31, 2023	KNOLL CAPITAL MANAGEMENT, LLC	0.24%	200.4K	893.78K	200K	+50,000.00%
Dec 31, 2023	INVESCO LTD.	0.26%	221.03K	985.78K	-28.91K	-11.57%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.26%	221.2K	986.56K	6.79K	+3.17%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.29%	243.36K	1.09M	3.05K	+1.27%
Dec 31, 2023	GSA CAPITAL PARTNERS LLP	0.29%	246.9K	1.1M	13.32K	+5.70%

Insiders

Among the OCUL insiders holding of 3.35% of the stake in company, SUMMER ROAD LLC, 10 percent owner, holds the largest shares of 8.59M. OPALEYE MANAGEMENT INC., 10 percent owner, is the second largest OCUL insider with ownership of 4.92M shares. DUGEL PRAVIN, See Remarks, stands third with possession of 3.01M shares of that stake.

Insiders	Designation	Shares Held
SUMMER ROAD LLC	10 percent owner	8.59M
OPALEYE MANAGEMENT INC.	10 percent owner	4.92M
DUGEL PRAVIN	See Remarks	3.01M
POLARIS VENTURE MANAGEMENT CO. V, L.L.C.	10 percent owner	1.96M
SAWHNEY AMARPREET	Chairman of the Board	1.06M
MATTESSICH ANTONY C.	President and CEO	588.7K
NOTMAN DONALD	Chief Operating Officer	366.36K
NAYAK SANJAY	Chief Strategy Officer	330.65K
HEIER JEFFREY S.	Chief Scientific Officer	323.37K
WAHEED NADIA	Chief Medical Officer	314.91K
KAISER PETER	Chief Development Officer	269.11K
LINDSTROM RICHARD L MD	director	246.93K
SAROJ NAMRATA	Chief Business Officer	174.14K
STRASSBURGER PHILIP C.	General Counsel	161.49K
OZDEN RABIA GURSES	Chief Medical Officer	153.05K
WHITE CHRISTOPHER G	Chief Business Officer	123.69K
FORTUNE JAMES	Chief Operating Officer	112.06K
ANDERMAN TODD	Chief Legal Officer	87.57K
ANKERUD ERIC	See Remarks	78.65K
SVLSF IV, LLC	10 percent owner	61.08K
BOLLAG DANIEL M	See Remarks	42.1K
GOLDSTEIN MICHAEL H.	Chief Medical Officer	25.69K
HANLEY KEVIN F.	See Remarks	20K
VERSANT VENTURE CAPITAL III, L.P.	10 percent owner	13.01K
WARDEN CHARLES M		13.01K
WILLIAMS LESLIE J.	director	4.5K
PEACOCK BRUCE	director	0

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Feb 23, 2026	KAISER PETER	SALE	8.28	2.81K	23.27K	269.11K
Feb 23, 2026	HEIER JEFFREY S.	SALE	8.28	3.06K	25.31K	323.37K
Feb 23, 2026	NAYAK SANJAY	SALE	8.28	1.76K	14.56K	330.65K
Feb 23, 2026	DUGEL PRAVIN	SALE	8.28	20.06K	166.06K	3.01M
Feb 20, 2026	WAHEED NADIA	SALE	7.74	3.51K	27.17K	314.91K
Feb 20, 2026	LINDSTROM RICHARD L MD	PURCHASE	7.66	60.23K	461.35K	246.93K
Feb 12, 2026	DUGEL PRAVIN	SALE	9.04	124.88K	1.13M	3.03M
Feb 12, 2026	NAYAK SANJAY	SALE	9.04	10.35K	93.55K	332.41K
Feb 12, 2026	NOTMAN DONALD	SALE	9.04	11.45K	103.47K	366.36K
Feb 12, 2026	WAHEED NADIA	SALE	9.04	7.86K	71.08K	318.42K
Feb 04, 2026	NOTMAN DONALD	SALE	8.54	6.04K	51.54K	377.8K
Feb 02, 2026	NOTMAN DONALD	SALE	9.14	5.46K	49.86K	383.84K
Nov 24, 2025	KAISER PETER	SALE	12.02	3.01K	36.14K	191.43K
Nov 24, 2025	HEIER JEFFREY S.	SALE	12.04	3.47K	41.77K	245.94K
Nov 24, 2025	NAYAK SANJAY	SALE	12.04	1.88K	22.61K	277.86K
Nov 24, 2025	DUGEL PRAVIN	SALE	12.04	19.53K	235.14K	3.16M
Nov 05, 2025	SAROJ NAMRATA	SALE	10.74	25.87K	277.79K	174.14K
Oct 08, 2025	ANDERMAN TODD	SALE	12.34	11.13K	137.37K	87.57K
Oct 02, 2025	HEIER JEFFREY S.	SALE	11.04	10.5K	115.94K	249.41K
Oct 02, 2025	KAISER PETER	SALE	11.03	9.65K	106.47K	194.44K
Sep 02, 2025	NOTMAN DONALD	SALE	12.43	1.07K	13.25K	308.81K
Aug 25, 2025	KAISER PETER	SALE	12.04	3.01K	36.25K	204.09K
Aug 25, 2025	DUGEL PRAVIN	SALE	12.04	21.49K	258.79K	3.23M
Aug 25, 2025	HEIER JEFFREY S.	SALE	12.04	3.06K	36.88K	259.91K
Aug 25, 2025	NAYAK SANJAY	SALE	12.04	1.89K	22.7K	279.74K
Jun 02, 2025	WAHEED NADIA	SALE	8.05	13.86K	111.58K	206.81K
May 23, 2025	NAYAK SANJAY	SALE	7.17	1.86K	13.35K	281.62K
May 23, 2025	DUGEL PRAVIN	SALE	7.18	21.22K	152.35K	3.5M
May 23, 2025	HEIER JEFFREY S.	SALE	7.18	3.02K	21.71K	262.97K
May 23, 2025	KAISER PETER	SALE	7.17	2.97K	21.32K	207.1K
May 08, 2025	LINDSTROM RICHARD L MD	PURCHASE	6.96	10K	69.6K	172.7K
Feb 24, 2025	HEIER JEFFREY S.	SALE	6.87	3.06K	21.03K	266K
Feb 24, 2025	DUGEL PRAVIN	SALE	6.87	21.48K	147.53K	3.52M
Feb 24, 2025	KAISER PETER	SALE	6.87	3.01K	20.67K	210.08K
Feb 24, 2025	NAYAK SANJAY	SALE	6.84	1.9K	12.96K	283.49K
Feb 04, 2025	NOTMAN DONALD	SALE	7.81	11.12K	86.84K	193.44K
Jan 31, 2025	NOTMAN DONALD	SALE	7.84	6.3K	49.4K	204.56K
Nov 25, 2024	NAYAK SANJAY	SALE	9.00	1.81K	16.33K	174.38K
Nov 25, 2024	HEIER JEFFREY S.	SALE	9.01	2.95K	26.56K	269.06K
Nov 25, 2024	KAISER PETER	SALE	9.01	2.9K	26.1K	213.09K
Nov 25, 2024	DUGEL PRAVIN	SALE	9.01	20.68K	186.33K	791.79K
Aug 23, 2024	DUGEL PRAVIN	SALE	9.02	20.88K	188.34K	812.47K
Aug 23, 2024	NAYAK SANJAY	SALE	9.02	1.83K	16.52K	176.19K
May 23, 2024	NAYAK SANJAY	SALE	5.84	2.27K	13.28K	178.03K
May 23, 2024	DUGEL PRAVIN	SALE	5.79	21.63K	125.21K	833.35K
Feb 26, 2024	SUMMER ROAD LLC	PURCHASE	7.52	930.85K	7M	8.59M
Feb 05, 2024	WHITE CHRISTOPHER G	SALE	4.86	5.91K	28.72K	123.69K
Feb 05, 2024	STRASSBURGER PHILIP C.	SALE	4.86	6.03K	29.3K	161.49K
Feb 05, 2024	OZDEN RABIA GURSES	SALE	4.86	6.35K	30.84K	153.05K
Feb 05, 2024	NOTMAN DONALD	SALE	4.86	6.21K	30.19K	195.36K
Feb 05, 2024	MATTESSICH ANTONY C.	SALE	4.86	19.64K	95.46K	588.7K
Jan 31, 2024	MATTESSICH ANTONY C.	SALE	4.95	18.34K	90.77K	427.94K
Jan 31, 2024	WHITE CHRISTOPHER G	SALE	4.95	5.15K	25.48K	89.62K
Jan 31, 2024	STRASSBURGER PHILIP C.	SALE	4.95	6.83K	33.81K	109.22K
Jan 31, 2024	OZDEN RABIA GURSES	SALE	4.95	7.76K	38.43K	92.77K
Jan 31, 2024	NOTMAN DONALD	SALE	4.95	6.43K	31.84K	139.93K
Dec 14, 2023	SUMMER ROAD LLC	PURCHASE	3.25	1.54M	5M	7.66M
Aug 30, 2023	MATTESSICH ANTONY C.	PURCHASE	3.81	6.5K	24.77K	6.5K
Jul 07, 2023	OZDEN RABIA GURSES	SALE	4.93	832	4.1K	100.53K
Feb 06, 2023	STRASSBURGER PHILIP C.	SALE	4.24	6.18K	26.21K	109.07K
Feb 06, 2023	MATTESSICH ANTONY C.	SALE	4.24	19.67K	83.4K	446.28K
Feb 06, 2023	NOTMAN DONALD	SALE	4.24	6.48K	27.46K	139.39K
Feb 06, 2023	WHITE CHRISTOPHER G	SALE	4.24	5.83K	24.71K	94.77K
Feb 06, 2023	OZDEN RABIA GURSES	SALE	4.24	6.42K	27.2K	101.36K
Nov 07, 2022	SUMMER ROAD LLC	PURCHASE	3.50	7.33K	25.65K	6.12M
Oct 11, 2022	SUMMER ROAD LLC	PURCHASE	3.90	10K	38.99K	6.11M
Oct 10, 2022	SUMMER ROAD LLC	PURCHASE	4.00	10K	39.98K	6.1M
Sep 29, 2022	SUMMER ROAD LLC	PURCHASE	4.04	18.8K	75.99K	6.09M
Sep 28, 2022	SUMMER ROAD LLC	PURCHASE	4.10	1.2K	4.92K	6.08M
Sep 27, 2022	SUMMER ROAD LLC	PURCHASE	4.68	130K	608.32K	6.07M
May 12, 2022	HEIER JEFFREY S.	PURCHASE	3.05	15K	45.75K	39K
Feb 23, 2022	SUMMER ROAD LLC	PURCHASE	4.80	10K	47.99K	5.94M
Feb 18, 2022	SUMMER ROAD LLC	PURCHASE	5.00	40K	199.94K	5.93M
Jan 28, 2022	SUMMER ROAD LLC	PURCHASE	5.20	4.02K	20.92K	5.89M
Jan 27, 2022	SUMMER ROAD LLC	PURCHASE	5.20	1.48K	7.68K	5.89M
Jan 24, 2022	SUMMER ROAD LLC	PURCHASE	5.31	44.4K	235.89K	5.89M
Jan 21, 2022	SUMMER ROAD LLC	PURCHASE	5.56	12.15K	67.53K	5.84M
Jan 20, 2022	SUMMER ROAD LLC	PURCHASE	5.70	17.95K	102.38K	5.83M
Jan 18, 2022	SUMMER ROAD LLC	PURCHASE	6.00	6.81K	40.83K	5.81M
Jan 14, 2022	SUMMER ROAD LLC	PURCHASE	6.03	33.19K	200.11K	5.81M
Jan 13, 2022	SUMMER ROAD LLC	PURCHASE	6.20	10K	61.98K	5.77M
Dec 15, 2021	SUMMER ROAD LLC	PURCHASE	6.22	15K	93.25K	5.76M
Dec 14, 2021	SUMMER ROAD LLC	PURCHASE	6.41	29.49K	189.18K	5.75M
Dec 13, 2021	SUMMER ROAD LLC	PURCHASE	6.50	10.51K	68.3K	5.72M
Dec 10, 2021	SUMMER ROAD LLC	PURCHASE	6.65	30K	199.49K	5.71M
Dec 08, 2021	SUMMER ROAD LLC	PURCHASE	6.75	5.3K	35.78K	5.68M
Dec 06, 2021	SUMMER ROAD LLC	PURCHASE	6.13	55.6K	340.83K	5.67M
Aug 20, 2021	MATTESSICH ANTONY C.	PURCHASE	9.89	5K	49.45K	102.9K
May 20, 2021	LINDSTROM RICHARD L MD	SALE	14.30	10K	143K	90K
Dec 03, 2020	PEACOCK BRUCE	SALE	18.36	25K	459K	0
Oct 16, 2020	SUMMER ROAD LLC	PURCHASE	10.48	437	4.58K	5.62M
May 19, 2020	SUMMER ROAD LLC	PURCHASE	5.50	363.64K	2M	5.62M
Mar 24, 2020	SUMMER ROAD LLC	PURCHASE	4.87	35.05K	170.71K	5.25M
Mar 23, 2020	SUMMER ROAD LLC	PURCHASE	4.66	64.95K	302.37K	5.22M
Mar 20, 2020	SUMMER ROAD LLC	PURCHASE	4.52	9.1K	41.12K	5.15M
Mar 19, 2020	SUMMER ROAD LLC	PURCHASE	4.63	40.9K	189.22K	5.15M
Mar 18, 2020	SUMMER ROAD LLC	PURCHASE	4.62	344.94K	1.59M	5.1M
Mar 17, 2020	SUMMER ROAD LLC	PURCHASE	4.66	550K	2.56M	4.76M
Mar 16, 2020	SUMMER ROAD LLC	PURCHASE	4.16	194.26K	807.22K	4.21M
Mar 13, 2020	SUMMER ROAD LLC	PURCHASE	4.63	210.8K	975.98K	4.02M
Jan 02, 2020	OPALEYE MANAGEMENT INC.	PURCHASE	3.90	15K	58.51K	4.92M
Dec 30, 2019	OPALEYE MANAGEMENT INC.	PURCHASE	3.97	5K	19.85K	207.5K
Jun 14, 2019	WILLIAMS LESLIE J.	PURCHASE	4.40	4.5K	19.8K	4.5K
Jun 14, 2019	NOTMAN DONALD	PURCHASE	4.33	2.5K	10.83K	24.05K
Jun 07, 2019	SAWHNEY AMARPREET	PURCHASE	3.02	65.47K	197.71K	1.06M
Jun 06, 2019	MATTESSICH ANTONY C.	PURCHASE	2.81	40K	112.4K	97.9K
Jun 06, 2019	SAWHNEY AMARPREET	PURCHASE	2.80	59K	165.2K	990.56K
Jun 05, 2019	SAWHNEY AMARPREET	PURCHASE	2.91	32.85K	95.6K	931.56K
Jun 04, 2019	SAWHNEY AMARPREET	PURCHASE	2.92	12.93K	37.75K	898.71K
May 28, 2019	GOLDSTEIN MICHAEL H.	PURCHASE	2.51	12K	30.12K	25.69K
Mar 15, 2019	HEIER JEFFREY S.	PURCHASE	4.15	24K	99.6K	24K
Mar 15, 2019	GOLDSTEIN MICHAEL H.	PURCHASE	4.15	10K	41.5K	13.69K
Mar 13, 2019	LINDSTROM RICHARD L MD	PURCHASE	4.33	56.44K	244.39K	100K
Dec 14, 2018	HANLEY KEVIN F.	PURCHASE	5.50	10K	55K	20K
Dec 10, 2018	HANLEY KEVIN F.	PURCHASE	5.60	10K	56K	10K
Dec 06, 2018	BOLLAG DANIEL M	PURCHASE	5.76	17.4K	100.22K	42.1K
Aug 20, 2018	MATTESSICH ANTONY C.	PURCHASE	5.95	20K	119K	57.9K
Aug 14, 2018	NOTMAN DONALD	PURCHASE	6.29	12.5K	78.63K	17.3K
Aug 10, 2018	MATTESSICH ANTONY C.	PURCHASE	6.23	16.9K	105.29K	37.9K
Dec 12, 2017	MATTESSICH ANTONY C.	PURCHASE	4.29	21K	90.09K	21K
Dec 07, 2017	NOTMAN DONALD	PURCHASE	4.00	4.8K	19.2K	4.8K
Dec 06, 2017	BOLLAG DANIEL M	PURCHASE	3.93	24.7K	97.07K	24.7K
Nov 16, 2017	SAWHNEY AMARPREET	PURCHASE	5.18	19K	98.42K	696.39K
Dec 15, 2016	SAWHNEY AMARPREET	PURCHASE	7.85	45.3K	355.61K	677.39K
Jun 09, 2016	SAWHNEY AMARPREET	PURCHASE	6.70	10K	67K	573.73K
Nov 17, 2015	SAWHNEY AMARPREET	PURCHASE	8.25	10K	82.5K	563.73K
Sep 15, 2015	FORTUNE JAMES	SALE	17.16	9.47K	162.51K	112.06K
Sep 14, 2015	SAWHNEY AMARPREET	PURCHASE	16.36	11.33K	185.33K	550.06K
Jun 15, 2015	VERSANT VENTURE CAPITAL III, L.P.	SALE	22.00	1.88K	41.32K	13.01K
Jun 15, 2015	WARDEN CHARLES M	SALE	22.00	1.88K	41.32K	13.01K
Jun 10, 2015	WARDEN CHARLES M	SALE	22.00	2.51K	55.13K	14.89K
Jun 10, 2015	SVLSF IV, LLC	SALE	22.00	10.3K	226.53K	61.08K
Jun 10, 2015	VERSANT VENTURE CAPITAL III, L.P.	SALE	22.00	2.51K	55.13K	14.89K
Feb 02, 2015	POLARIS VENTURE MANAGEMENT CO. V, L.L.C.	SALE	29.50	482.47K	14.23M	1.96M
Jul 30, 2014	ANKERUD ERIC	PURCHASE	13.00	1K	13K	78.65K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE60.23K1

SALES282.26K19

NET SHARES-222.03K18

SHARES HELD13.89M20

% NET SHARES-101.6%-10%

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