How many institutions own LXRX stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own LXRX shares is 151, representing 72.07% of the company's common stock.

Who are the major shareholders selling Lexicon Pharmaceuticals, Inc. stock?

CERITY PARTNERS LLC, in the last quarter, reduced its stake in LXRX by -8.29% restricting it's holding to 144.94 thousand shares of worth nearly $166.69K. CAMBRIDGE INVESTMENT RESEARCH ADVISORS, INC. also lessened -8.1% of the LXRX shares from its portfolio, reducing its holding to 21.51 thousand shares of worth $25.00K. PINNACLE ASSOCIATES LTD also shunned LXRX shares holding by -42.9% last quarter which brought its holding to 29.02 thousand shares worth $33.37K.

Investors who are buying LXRX stock?

As per its latest 13F filing, SUSQUEHANNA INTERNATIONAL GROUP, LLP increased its stake in LXRX by 3.58% in the last quarter. The institutional holder raised its holding to 136.1 thousand shares having worth more than $156.52M. CAXTON ASSOCIATES LLP also added 100% more shares of LXRX to its portfolio, raising its holding to 71.03 thousand shares of worth $81.68K. CALLAN FAMILY OFFICE, LLC also increased its LXRX shares holding by 100% which brought its holding to 14.09 thousand shares worth $16.20K.

LXRX's major insiders: who are they?

The insider with the most stakes in LXRX is Artal International S.C.A. , at the company. Additionally, LXRX stock is highly held by Invus Advisors, L.L.C. and Invus Public Equities, L.P. among others.

Did an insider recently sell LXRX stock?

Company executives, directors, and other insiders own 1.17% percent of Lexicon Pharmaceuticals, Inc.'s stock. Within the last six months, there have been 0 transaction(s) in which LXRX insiders have sold stock, totaling 0 shares. Insiders that have sold shares include TESSMER JAMES F.

Which insider recently purchased LXRX stock?

There have been 4 transaction(s) during the past 6-months in which Lexicon Pharmaceuticals, Inc. insiders have bought stock, totalling 1806959 shares

How much of LXRX does insiders own?

Around 6.16M Lexicon Pharmaceuticals, Inc. shares are held by insiders, which represents about 1.17% of LXRX stock.

Who is the insider with the largest stake?

LXRX , Artal International S.C.A. holds the largest portfolio of the company's shares. LXRX shares owned by Artal total nearly 78.63 million.

Which institution holds the most shares in LXRX?

CERITY PARTNERS LLC is the largest institutional owner in LXRX which holds 144.94 thousand shares worth $166.69K or 0.04% of the total LXRX shares outstanding followed by SUSQUEHANNA INTERNATIONAL GROUP, LLP with ownership of 136.1 thousand shares representing 0.04% of the LXRX ownership. BANK OF MONTREAL /CAN/ is the third largest stakeholder with 70 thousand shares or 0.02% of the ownership worth more than $80.50K.

Is Lexicon Pharmaceuticals, Inc. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the LXRX is concerned, it is a stock which is optionable.

Is there a short position on LXRX's shares?

Number of LXRX shares short is 27.91M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding LXRX shares are there?

As of today, 363.40M shares of LXRX are outstanding.

Is there many float in LXRX stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, LXRX has 183.89M shares in float.

LXRX short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for LXRX is 8.92.

Lexicon Pharmaceuticals (LXRX) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares7.68

Short Percent Of Float21.44

Shares Outstanding363.40M

Shares Float183.89M

Shares Short27.91M

Short Ratio8.92

21.44%

Short % of Float

7.68%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

1.17% Percentage of Shares held by All Insiders

72.07% Percentage of Shares held by All Institutions

72.93% Percentage of Float held by Institutions

151

Number of Institutions Holding Shares

Institutional Ownership

About 72.07% of LXRX shares are held by financial institutions. CERITY PARTNERS LLC is the top corporate investor, holding 144.94K shares valued at $166.69K. A 0.04% stake in Lexicon Pharmaceuticals, Inc. is owned by the company. SUSQUEHANNA INTERNATIONAL GROUP, LLP owns 136.1K shares valued at $156.52M, which translates its holding of 0.04% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Dec 31, 2025	CERITY PARTNERS LLC	0.04%	144.94K	166.69K	-13.1K	-8.29%
Dec 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.04%	136.1K	156.52M	4.7K	+3.58%
Dec 31, 2025	BANK OF MONTREAL /CAN/	0.02%	70K	80.5K	0	0
Dec 31, 2025	CAXTON ASSOCIATES LLP	0.02%	71.03K	81.68K	71.03K	+100.00%
Dec 31, 2025	CALLAN FAMILY OFFICE, LLC	0%	14.09K	16.2K	14.09K	+100.00%
Dec 31, 2025	BANK OF NEW YORK MELLON CORP	0.01%	19.12K	21.99K	0	0
Dec 31, 2025	TIAA TRUST, NATIONAL ASSOCIATION	0.01%	20K	23K	0	0
Dec 31, 2025	INVERA WEALTH ADVISORS, LLC	0.01%	20K	23K	0	0
Dec 31, 2025	CAMBRIDGE INVESTMENT RESEARCH ADVISORS, INC.	0.01%	21.51K	25K	-1.9K	-8.10%
Dec 31, 2025	OPPENHEIMER & CO INC	0.01%	23.5K	27.03K	0	0
Dec 31, 2025	PINNACLE ASSOCIATES LTD	0.01%	29.02K	33.37K	-21.8K	-42.90%
Dec 31, 2025	SIMPLEX TRADING, LLC	0%	14.76K	16.97K	-58.53K	-79.86%
Dec 31, 2025	STONEX GROUP INC.	0%	16.23K	18.67K	16.23K	+100.00%
Dec 31, 2025		0.01%	30K	34.5K	30K	+100.00%
Dec 31, 2025	SIREN, L.L.C.	10.71%	38.92M	44.76M	0	0
Dec 31, 2025	ARTAL GROUP S.A.	37.47%	136.18M	156.61M	0	0
Dec 31, 2025	LPL FINANCIAL LLC	0.02%	87.06K	100.12K	-4.2K	-4.60%
Dec 31, 2025	CITIGROUP INC	0.03%	91.67K	105.42K	73.55K	+405.93%
Dec 31, 2025	R SQUARED LTD	0.01%	46.58K	53.57K	14.53K	+45.34%
Dec 31, 2025	FORTIS GROUP ADVISORS, LLC	0.01%	50K	58K	-7.8K	-13.49%
Dec 31, 2025	SQUAREPOINT OPS LLC	0.02%	60.47K	69.54K	1.8K	+3.06%
Dec 31, 2025	STATE OF WYOMING	0.02%	60.57K	69.66K	52.05K	+610.43%
Dec 31, 2025	STRAIGHT PATH WEALTH MANAGEMENT	0.02%	62.67K	72.07K	0	0
Dec 31, 2025	CITADEL ADVISORS LLC	0.02%	85.3K	98.1M	-11.3K	-11.70%
Dec 31, 2025	XTX TOPCO LTD	0.03%	96.09K	110.5M	-233.45K	-70.84%
Dec 31, 2025	HUDSON BAY CAPITAL MANAGEMENT LP	0.03%	100.53K	115.61K	100.53K	+100.00%
Dec 31, 2025	BANK OF AMERICA CORP /DE/	0.03%	102.1K	117.41M	44.29K	+76.63%
Dec 31, 2025	TWO SIGMA SECURITIES, LLC	0.03%	114.63K	131.83K	98.75K	+621.82%
Dec 31, 2025	LIGHTHOUSE INVESTMENT PARTNERS, LLC	0.03%	126.6K	145.59M	126.6K	+100.00%
Dec 31, 2025	AQR CAPITAL MANAGEMENT LLC	0.04%	144.8K	166.52K	-158.13K	-52.20%
Dec 31, 2025	TWO SIGMA ADVISERS, LP	0.05%	180.98K	208.12K	180.98K	+100.00%
Dec 31, 2025	MORGAN STANLEY	0.05%	193.04K	221.99M	24.02K	+14.21%
Dec 31, 2025	BARCLAYS PLC	0.05%	194.74K	223.95M	162.88K	+511.21%
Dec 31, 2025	GROUP ONE TRADING, L.P.	0.06%	224.31K	257.95M	8.06K	+3.73%
Dec 31, 2025	RENAISSANCE TECHNOLOGIES LLC	0.07%	263.25K	302.74M	-29.15K	-9.97%
Dec 31, 2025	OMERS ADMINISTRATION CORP	0.08%	273.8K	314.87K	273.8K	+100.00%
Dec 31, 2025	COMPAGNIE LOMBARD ODIER SCMA	0.11%	410K	471.5K	0	0
Dec 31, 2025	TWO SIGMA INVESTMENTS, LP	0.18%	637.31K	732.9M	78.3K	+14.01%
Dec 31, 2025	ACADIAN ASSET MANAGEMENT LLC	0.18%	640.13K	732K	603.23K	+1,634.53%
Dec 31, 2025	STATE STREET CORP	0.24%	884.74K	1.02M	4.62K	+0.52%
Dec 31, 2025	HENNION & WALSH ASSET MANAGEMENT, INC.	0.25%	901.22K	1.04M	122.01K	+15.66%
Dec 31, 2025	GOLDMAN SACHS GROUP INC	0.25%	921.2K	1.06B	861.86K	+1,452.23%
Dec 31, 2025	GSA CAPITAL PARTNERS LLP	0.27%	996.24K	1.15M	-206.67K	-17.18%
Dec 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.29%	1.06M	1.21M	-89.51K	-7.82%
Dec 31, 2025	MARSHALL WACE, LLP	0.35%	1.26M	1.45M	1.26M	+100.00%
Dec 31, 2025	CIBC PRIVATE WEALTH GROUP, LLC	0.54%	1.95M	2.24M	-450.26K	-18.76%
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.69%	2.5M	2.88B	102.1K	+4.26%
Dec 31, 2025	UBS GROUP AG	0.83%	3.01M	3.46B	2.65M	+752.10%
Dec 31, 2025	BLACKROCK, INC.	0.88%	3.19M	3.67B	-202.52K	-5.97%
Dec 31, 2025	MILLENNIUM MANAGEMENT LLC	1.33%	4.82M	5.54B	991.07K	+25.87%
Dec 31, 2025	VANGUARD GROUP INC	2.64%	9.61M	11.05B	84.68K	+0.89%
Dec 31, 2025	JEFFERIES FINANCIAL GROUP INC.	0.03%	92.53K	106.41K	-4.87K	-5.00%
Dec 31, 2025	JANE STREET GROUP, LLC	0.03%	104.1K	119.72M	104.1K	+100.00%
Dec 31, 2025	MONACO ASSET MANAGEMENT SAM	0.03%	117.19K	134.77K	-232.81K	-66.52%
Dec 31, 2025	PATHSTONE HOLDINGS, LLC	0.01%	29.97K	34.46K	-239	-0.79%
Dec 31, 2025	ENTRYPOINT CAPITAL, LLC	0.01%	33.62K	38.66K	33.62K	+100.00%
Dec 31, 2025	CIBC ASSET MANAGEMENT INC	0.01%	39.52K	45.45K	39.52K	+100.00%
Dec 31, 2025	CATALYST FUNDS MANAGEMENT PTY LTD	0.01%	40.3K	46.35K	0	0
Dec 31, 2025	KWB WEALTH	0.01%	40.64K	46.74K	0	0
Dec 31, 2025	WEDBUSH SECURITIES INC	0.01%	40.85K	47K	0	0
Dec 31, 2025	HRT FINANCIAL LP	0.03%	117.55K	135K	71.1K	+153.08%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.66%	2.4M	3.24M	20.23K	+0.85%
Sep 30, 2025	CITADEL ADVISORS LLC	0.03%	96.6K	130.41K	46.3K	+92.05%
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.08%	292.4K	394.74K	292.4K	+100.00%
Sep 30, 2025	AQR CAPITAL MANAGEMENT LLC	0.08%	302.93K	408.96K	-1.1M	-78.40%
Sep 30, 2025	XTX TOPCO LTD	0.09%	329.54K	444.87K	263.26K	+397.22%
Sep 30, 2025	MONACO ASSET MANAGEMENT SAM	0.1%	350K	472.5K	-181.6K	-34.16%
Sep 30, 2025	UBS GROUP AG	0.1%	352.92K	476.45K	-47.81K	-11.93%
Sep 30, 2025	VANGUARD GROUP INC	2.62%	9.52M	12.85M	670.84K	+7.58%
Sep 30, 2025	JANE STREET GROUP, LLC	0.13%	456.53K	616.32K	-348.14K	-43.26%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.32%	1.14M	1.55M	261.41K	+29.60%
Sep 30, 2025	GSA CAPITAL PARTNERS LLP	0.33%	1.2M	1.62M	-1.63M	-57.50%
Sep 30, 2025	MILLENNIUM MANAGEMENT LLC	1.05%	3.83M	5.17M	2.19M	+133.11%
Sep 30, 2025	ARTAL GROUP S.A.	37.48%	136.18M	183.84M	0	0
Sep 30, 2025	STATE STREET CORP	0.24%	880.12K	1.19M	61.5K	+7.51%
Sep 30, 2025	TWO SIGMA INVESTMENTS, LP	0.15%	559.01K	754.66K	155.09K	+38.40%
Sep 30, 2025	NORTHERN TRUST CORP	0.1%	369.79K	499.22K	-46.58K	-11.19%
Sep 30, 2025	IKARIAN CAPITAL, LLC	0.05%	176.48K	238.25K	0	0
Sep 30, 2025	BANK OF MONTREAL /CAN/	0.02%	70K	94.5K	-30K	-30.00%
Sep 30, 2025	HENNION & WALSH ASSET MANAGEMENT, INC.	0.21%	779.21K	1.05M	-14.19K	-1.79%
Sep 30, 2025	OPTIVER HOLDING B.V.	0.02%	75.89K	102.46K	72.86K	+2,400.59%
Sep 30, 2025	SIMPLEX TRADING, LLC	0.02%	73.29K	98K	20.61K	+39.12%
Sep 30, 2025	CAPTION MANAGEMENT, LLC	0.55%	2M	2.7M	2M	+100.00%
Sep 30, 2025	SESSA CAPITAL IM, L.P.	0.83%	3M	4.05M	0	0
Sep 30, 2025	BLACKROCK, INC.	0.93%	3.39M	4.58M	40.3K	+1.20%
Sep 30, 2025		0.66%	2.4M	3.24M	2.4M	+100.00%
Sep 30, 2025	COMMONWEALTH EQUITY SERVICES, LLC	0.01%	35.74K	48K	-55.13K	-60.67%
Sep 30, 2025	ACADIAN ASSET MANAGEMENT LLC	0.01%	36.91K	49K	36.91K	+100.00%
Sep 30, 2025	CATALYST FUNDS MANAGEMENT PTY LTD	0.01%	40.3K	54.41K	-13.4K	-24.95%
Sep 30, 2025	WEDBUSH SECURITIES INC	0.01%	40.85K	55K	0	0
Sep 30, 2025	HRT FINANCIAL LP	0.01%	46.45K	62K	-442.02K	-90.49%
Sep 30, 2025	HEADLANDS TECHNOLOGIES LLC	0.01%	49.65K	67.02K	49.65K	+100.00%
Sep 30, 2025	PINNACLE ASSOCIATES LTD	0.01%	50.82K	68.6K	0	0
Sep 30, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.02%	56.12K	75.76K	0	0
Sep 30, 2025	FORTIS GROUP ADVISORS, LLC	0.02%	57.8K	79.76K	0	0
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.02%	57.8K	78.04K	25.71K	+80.09%
Sep 30, 2025	SQUAREPOINT OPS LLC	0.02%	58.68K	79.21K	-36.94K	-38.63%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	0.02%	59.35K	80.12K	-266.4K	-81.78%
Sep 30, 2025	STRAIGHT PATH WEALTH MANAGEMENT	0.02%	62.67K	84.6K	0	0
Sep 30, 2025	CUBIST SYSTEMATIC STRATEGIES, LLC	0.02%	63.48K	85.7K	-94.72K	-59.87%
Sep 30, 2025	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.02%	63.7K	85.99K	-9.25K	-12.67%
Sep 30, 2025	VANGUARD PERSONALIZED INDEXING MANAGEMENT, LLC	0.02%	66.57K	89.87K	1.24K	+1.89%
Sep 30, 2025	CIBC PRIVATE WEALTH GROUP, LLC	0.66%	2.4M	3.24M	-50.14K	-2.05%
Sep 30, 2025	LPL FINANCIAL LLC	0.03%	91.26K	123.2K	-13.18K	-12.62%
Sep 30, 2025	JEFFERIES FINANCIAL GROUP INC.	0.03%	97.4K	131.49K	97.4K	+100.00%
Sep 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.03%	115.8K	156.33K	-6K	-4.93%
Sep 30, 2025	CERITY PARTNERS LLC	0.04%	158.04K	213.35K	-48.24K	-23.39%
Sep 30, 2025	MORGAN STANLEY	0.05%	169.02K	228.18K	37.63K	+28.64%
Sep 30, 2025	GROUP ONE TRADING, L.P.	0.06%	216.24K	291.93K	-130.51K	-37.64%
Sep 30, 2025	QUADRATURE CAPITAL LTD	0.06%	228.21K	309.22K	228.21K	+100.00%
Sep 30, 2025	COMPAGNIE LOMBARD ODIER SCMA	0.11%	410K	553.5K	80K	+24.24%
Sep 30, 2025	JACOBS LEVY EQUITY MANAGEMENT, INC	0.19%	692.73K	935.18K	692.73K	+100.00%
Sep 30, 2025	ROYAL BANK OF CANADA	0.2%	722.44K	975K	-52.04K	-6.72%
Sep 30, 2025	SCHONFELD STRATEGIC ADVISORS LLC	0.23%	825.63K	1.11M	-3.75M	-81.96%
Sep 30, 2025	INVESCO LTD.	0.14%	521.4K	703.89K	100.7K	+23.94%
Sep 30, 2025	SBI SECURITIES CO., LTD.	0%	15.05K	20.31K	-4.19K	-21.78%
Sep 30, 2025	CITIGROUP INC	0.01%	18.12K	24.46K	-30.43K	-62.68%
Sep 30, 2025	WEALTH ENHANCEMENT ADVISORY SERVICES, LLC	0.01%	18.88K	28.69K	-55.58K	-74.65%
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.01%	19.12K	25.82K	0	0
Sep 30, 2025	TIAA TRUST, NATIONAL ASSOCIATION	0.01%	20K	27K	0	0
Sep 30, 2025	INVERA WEALTH ADVISORS, LLC	0.01%	20K	27K	0	0
Sep 30, 2025	VICTORY CAPITAL MANAGEMENT INC	0.01%	21.02K	28.38K	-92	-0.44%
Sep 30, 2025	CAMBRIDGE INVESTMENT RESEARCH ADVISORS, INC.	0.01%	23.4K	32K	1.9K	+8.84%
Sep 30, 2025	OPPENHEIMER & CO INC	0.01%	23.5K	31.73K	0	0
Sep 30, 2025	CWM, LLC	0.01%	26.74K	36K	-82.59K	-75.54%
Sep 30, 2025	JPMORGAN CHASE & CO	0.01%	30.04K	40.55K	5.35K	+21.69%
Sep 30, 2025	PATHSTONE HOLDINGS, LLC	0.01%	30.21K	40.78K	167	+0.56%
Sep 30, 2025	BARCLAYS PLC	0.01%	31.86K	43.01K	-408	-1.26%
Sep 30, 2025	R SQUARED LTD	0.01%	32.05K	43.27K	2.49K	+8.42%
Sep 30, 2025	PRUDENTIAL FINANCIAL INC	0.01%	35K	47.24K	35K	+100.00%
Sep 30, 2025	UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGMENT CO	0.01%	35.71K	48.21K	0	0
Sep 30, 2025	KWB WEALTH	0.01%	40.64K	38.43K	0	0
Sep 30, 2025	FMR LLC	10.65%	38.68M	52.22M	542.21K	+1.42%
Sep 30, 2025	SIREN, L.L.C.	10.71%	38.92M	52.54M	0	0
Jun 30, 2025	CERITY PARTNERS LLC	0.06%	206.28K	195.08K	35.89K	+21.07%
Jun 30, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.02%	56.12K	53.07K	-398.77K	-87.66%
Jun 30, 2025	JUMP FINANCIAL, LLC	0%	15.99K	15.13K	15.99K	+100.00%
Jun 30, 2025	CHEMISTRY WEALTH MANAGEMENT LLC	0%	12K	11.35K	0	0
Jun 30, 2025	HBK SORCE ADVISORY LLC	0%	11.79K	11.15K	11.79K	+100.00%
Jun 30, 2025	AVANTAX ADVISORY SERVICES, INC.	0%	11.72K	11.09K	0	0
Jun 30, 2025	NORTH STAR ASSET MANAGEMENT INC	0%	11.5K	10.88K	0	0
Jun 30, 2025	GROUP ONE TRADING, L.P.	0.1%	346.75K	327.92K	-19.05K	-5.21%
Jun 30, 2025	WEALTH ENHANCEMENT ADVISORY SERVICES, LLC	0.02%	74.45K	67.08K	5.25K	+7.58%
Jun 30, 2025	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.02%	72.94K	68.98K	434	+0.60%
Jun 30, 2025	SAVANT CAPITAL, LLC	0.02%	69.58K	65.8K	17.35K	+33.21%
Jun 30, 2025	XTX TOPCO LTD	0.02%	66.28K	62.68K	53.81K	+431.44%
Jun 30, 2025	STRAIGHT PATH WEALTH MANAGEMENT	0.02%	62.67K	59.26K	0	0
Jun 30, 2025	VANGUARD GROUP INC	2.44%	8.85M	8.37M	-706.14K	-7.39%
Jun 30, 2025	GSA CAPITAL PARTNERS LLP	0.78%	2.83M	2.68M	2.02M	+250.55%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.65%	2.38M	2.25M	-1.31M	-35.55%
Jun 30, 2025	IKARIAN CAPITAL, LLC	0.05%	176.48K	166.9K	-1.24M	-87.55%
Jun 30, 2025	CUBIST SYSTEMATIC STRATEGIES, LLC	0.04%	158.2K	149.61K	144.41K	+1,046.66%
Jun 30, 2025	VIRTU FINANCIAL LLC	0.04%	146.81K	139K	146.81K	+100.00%
Jun 30, 2025	CWM, LLC	0.03%	109.33K	103K	3.83K	+3.63%
Jun 30, 2025	BANK OF MONTREAL /CAN/	0.03%	100K	94.57K	0	0
Jun 30, 2025	SQUAREPOINT OPS LLC	0.03%	95.62K	90.43K	-99.79K	-51.07%
Jun 30, 2025	COMPAGNIE LOMBARD ODIER SCMA	0.09%	330K	312.08K	220K	+200.00%
Jun 30, 2025	IEQ CAPITAL, LLC	0.05%	192.1K	181.67K	14.8K	+8.35%
Jun 30, 2025	SESSA CAPITAL IM, L.P.	0.83%	3M	2.84M	3M	+100.00%
Jun 30, 2025	MILLENNIUM MANAGEMENT LLC	0.45%	1.64M	1.55M	1.64M	+100.00%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.24%	883.23K	835.27K	-267.54K	-23.25%
Jun 30, 2025	STATE STREET CORP	0.23%	818.62K	774.17K	-1.79M	-68.61%
Jun 30, 2025	WELLINGTON MANAGEMENT GROUP LLP	0.13%	486.67K	460.25K	486.67K	+100.00%
Jun 30, 2025	INVESCO LTD.	0.12%	420.7K	397.86K	134.94K	+47.22%
Jun 30, 2025	JANE STREET GROUP, LLC	0.02%	62.6K	59.2K	62.6K	+100.00%
Jun 30, 2025	SCIENTECH RESEARCH LLC	0.02%	57.86K	54.72K	57.86K	+100.00%
Jun 30, 2025	AQR CAPITAL MANAGEMENT LLC	0.39%	1.4M	1.33B	228.99K	+19.52%
Jun 30, 2025	PINNACLE ASSOCIATES LTD	0.01%	50.82K	48.06K	-3.37K	-6.21%
Jun 30, 2025	D. E. SHAW & CO., INC.	0.01%	23.72K	22.44M	23.72K	+100.00%
Jun 30, 2025	MERIT FINANCIAL GROUP, LLC	0%	16.7K	15.79K	1.21K	+7.79%
Jun 30, 2025	MIRAE ASSET GLOBAL INVESTMENTS CO., LTD.	0%	14.03K	13.27K	1.93K	+15.98%
Jun 30, 2025	SIREN, L.L.C.	10.71%	38.92M	36.81M	0	0
Jun 30, 2025	FMR LLC	10.5%	38.14M	36.07M	3.59M	+10.41%
Jun 30, 2025	SCHONFELD STRATEGIC ADVISORS LLC	1.26%	4.58M	4.33M	-3.64M	-44.28%
Jun 30, 2025	BLACKROCK, INC.	0.92%	3.35M	3.17M	-6.66M	-66.50%
Jun 30, 2025	MORGAN STANLEY	0.04%	131.39K	124.26M	-510.24K	-79.52%
Jun 30, 2025	TWO SIGMA SECURITIES, LLC	0.01%	42.41K	40.1K	42.41K	+100.00%
Jun 30, 2025	WEDBUSH SECURITIES INC	0.01%	40.85K	39K	0	0
Jun 30, 2025	KWB WEALTH	0.01%	40.64K	18.73K	0	0
Jun 30, 2025	PALLAS CAPITAL ADVISORS LLC	0.01%	36.77K	34.77K	557	+1.54%
Jun 30, 2025	UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGMENT CO	0.01%	35.71K	33.79K	0	0
Jun 30, 2025	CAPTRUST FINANCIAL ADVISORS	0.01%	35.58K	33.65K	2.4K	+7.23%
Jun 30, 2025	PATHSTONE HOLDINGS, LLC	0.01%	30.04K	28.41K	-1.36K	-4.32%
Jun 30, 2025	HUDSON BAY CAPITAL MANAGEMENT LP	0.01%	27.01K	25.54K	27.01K	+100.00%
Jun 30, 2025	WOLVERINE TRADING, LLC	0.01%	21.1K	17.32K	-4.8K	-18.53%
Jun 30, 2025	TIAA TRUST, NATIONAL ASSOCIATION	0.01%	20K	18.91K	0	0
Jun 30, 2025	INTEGRATED WEALTH CONCEPTS LLC	0%	16.21K	15.33K	16.21K	+100.00%
Jun 30, 2025	BUCKINGHAM STRATEGIC PARTNERS	0%	13.75K	13K	1.65K	+13.64%
Jun 30, 2025	EXODUSPOINT CAPITAL MANAGEMENT, LP	0%	12.24K	12K	12.24K	+100.00%
Jun 30, 2025		0.02%	84.1K	79.53K	84.1K	+100.00%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.02%	87.5K	83.13K	73.2K	+511.89%
Jun 30, 2025	LPL FINANCIAL LLC	0.03%	104.43K	98.76K	33.48K	+47.18%
Jun 30, 2025	COMMONWEALTH EQUITY SERVICES, LLC	0.03%	90.86K	86K	0	0
Jun 30, 2025	POINT72 ASIA (SINGAPORE) PTE. LTD.	0.02%	70.05K	66.24K	-101.1K	-59.07%
Jun 30, 2025	VANGUARD PERSONALIZED INDEXING MANAGEMENT, LLC	0.02%	65.33K	61.78K	28.59K	+77.84%
Jun 30, 2025	CIBC PRIVATE WEALTH GROUP, LLC	0.67%	2.45M	2.32M	210.4K	+9.39%
Jun 30, 2025	HENNION & WALSH ASSET MANAGEMENT, INC.	0.22%	793.4K	750.32K	-36.65K	-4.42%
Jun 30, 2025	ROYAL BANK OF CANADA	0.21%	774.47K	732K	771.32K	+24,416.43%
Jun 30, 2025	MONACO ASSET MANAGEMENT SAM	0.15%	531.6K	502.73K	-202.55K	-27.59%
Jun 30, 2025	HRT FINANCIAL LP	0.13%	488.47K	461K	488.47K	+100.00%
Jun 30, 2025	NORTHERN TRUST CORP	0.11%	416.37K	393.76K	-693.52K	-62.49%
Jun 30, 2025	TWO SIGMA INVESTMENTS, LP	0.11%	403.92K	381.99K	403.92K	+100.00%
Jun 30, 2025	FORTIS GROUP ADVISORS, LLC	0.02%	57.8K	61.85K	20K	+52.91%
Jun 30, 2025	ARTAL GROUP S.A.	37.48%	136.18M	129.37M	0	0
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.09%	325.75K	308.06M	-29.41K	-8.28%
Jun 30, 2025	CITADEL ADVISORS LLC	0.06%	225.3K	213.07M	87.6K	+63.62%
Jun 30, 2025	UBS GROUP AG	0.11%	400.73K	379.09K	-1.69M	-80.88%
Jun 30, 2025	JAIN GLOBAL LLC	0.04%	151.81K	143.57K	151.81K	+100.00%
Jun 30, 2025	ASTER CAPITAL MANAGEMENT (DIFC) LTD	0.04%	130.45K	123.37K	130.45K	+100.00%
Jun 30, 2025	QUANTESSENCE CAPITAL LLC	0.02%	84.1K	79.53K	84.1K	+100.00%
Mar 31, 2025	ARTAL GROUP S.A.	37.61%	136.18M	62.64M	0	0
Mar 31, 2025	FMR LLC	9.54%	34.54M	15.92M	-17.43M	-33.53%
Mar 31, 2025	CWM, LLC	0.03%	105.5K	49K	104.37K	+9,228.38%
Mar 31, 2025	AQR CAPITAL MANAGEMENT LLC	0.32%	1.17M	540.62K	1.17M	+100.00%
Mar 31, 2025	GSA CAPITAL PARTNERS LLP	0.22%	807.49K	372K	807.49K	+100.00%
Mar 31, 2025	BANK OF NEW YORK MELLON CORP	0.09%	310.12K	142.9K	-4.8K	-1.52%
Mar 31, 2025	COMMONWEALTH EQUITY SERVICES, LLC	0.03%	90.86K	42K	-10.28K	-10.17%
Mar 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.02%	89.11K	41.06K	69.41K	+352.26%
Mar 31, 2025	BLACKROCK, INC.	2.77%	10.01M	4.61M	-320.15K	-3.10%
Mar 31, 2025	VANGUARD GROUP INC	2.64%	9.56M	4.41M	-324.55K	-3.28%
Mar 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.26%	951.14K	438.28K	400.24K	+72.65%
Mar 31, 2025	MORGAN STANLEY	0.18%	641.63K	295.66K	115.48K	+21.95%
Mar 31, 2025	ACADIAN ASSET MANAGEMENT LLC	0.16%	573.69K	263K	573.69K	+100.00%
Mar 31, 2025	BBR PARTNERS, LLC	0.16%	570K	262.66K	100K	+21.28%
Mar 31, 2025	NANTAHALA CAPITAL MANAGEMENT, LLC	0.13%	460.85K	212.36K	-6.14M	-93.02%
Mar 31, 2025	SCHONFELD STRATEGIC ADVISORS LLC	2.27%	8.21M	3.78M	654.37K	+8.66%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.02%	3.69M	1.7M	168.02K	+4.77%
Mar 31, 2025	HENNION & WALSH ASSET MANAGEMENT, INC.	0.23%	830.05K	382.49K	-33.2K	-3.85%
Mar 31, 2025	UBS GROUP AG	0.58%	2.1M	965.95K	1.41M	+205.39%
Mar 31, 2025	IKARIAN CAPITAL, LLC	0.39%	1.42M	653.39K	-132.05K	-8.52%
Mar 31, 2025	CITADEL ADVISORS LLC	0.04%	137.7K	63.45K	104K	+308.61%
Mar 31, 2025	INVESCO LTD.	0.08%	285.76K	131.68K	181.27K	+173.47%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.32%	1.15M	530.28K	-40.32K	-3.39%
Mar 31, 2025	TANG CAPITAL MANAGEMENT LLC	0.32%	1.15M	530.04K	300K	+35.28%
Mar 31, 2025	NORTHERN TRUST CORP	0.31%	1.11M	511.44K	-198.76K	-15.19%
Mar 31, 2025	POINT72 ASIA (SINGAPORE) PTE. LTD.	0.05%	171.15K	78.87K	171.15K	+100.00%
Mar 31, 2025	CERITY PARTNERS LLC	0.05%	170.39K	78.51K	73.88K	+76.54%
Mar 31, 2025	BARCLAYS PLC	0.04%	146.07K	67K	-97.25K	-39.97%
Mar 31, 2025	RHUMBLINE ADVISERS	0.04%	137.23K	63.25K	-15.92K	-10.40%
Mar 31, 2025	BANK OF MONTREAL /CAN/	0.03%	100K	46.08K	30K	+42.86%
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	0.03%	100K	46.08K	100K	+100.00%
Mar 31, 2025	CITIGROUP INC	0.03%	96.97K	44.68K	-9.82K	-9.19%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0.03%	96.39K	44.34K	-40.02K	-29.34%
Mar 31, 2025	DEUTSCHE BANK AG\	0.03%	94.39K	43.42K	-221.27K	-70.10%
Mar 31, 2025	JPMORGAN CHASE & CO	0.02%	88.2K	40.64K	582	+0.66%
Mar 31, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.02%	73.85K	34.03K	17.16K	+30.28%
Mar 31, 2025	MONACO ASSET MANAGEMENT SAM	0.2%	734.15K	338.3K	734.15K	+100.00%
Mar 31, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.13%	454.89K	209.61K	-25.93K	-5.39%
Mar 31, 2025	VIRTUS INVESTMENT ADVISERS, INC.	0.12%	436.67K	201.22K	436.67K	+100.00%
Mar 31, 2025	GROUP ONE TRADING, L.P.	0.1%	365.81K	168.56K	51.4K	+16.35%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.1%	355.15K	163.65K	-185.06K	-34.26%
Mar 31, 2025	ALLIANCEBERNSTEIN L.P.	0.07%	246.12K	113.41K	0	0
Mar 31, 2025	SQUAREPOINT OPS LLC	0.05%	195.41K	90.04K	195.41K	+100.00%
Mar 31, 2025	IEQ CAPITAL, LLC	0.05%	177.3K	81.7K	177.3K	+100.00%
Mar 31, 2025	SIMPLEX TRADING, LLC	0.05%	174.98K	80K	78.9K	+82.12%
Mar 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	0.03%	92.25K	43K	14.75K	+19.03%
Mar 31, 2025	CIBC PRIVATE WEALTH GROUP, LLC	0.62%	2.24M	1.12M	2.24M	+100.00%
Mar 31, 2025	STATE STREET CORP	0.72%	2.61M	1.2M	-110.67K	-4.07%
Mar 31, 2025	COMPAGNIE LOMBARD ODIER SCMA	0.03%	110K	50.69K	0	0
Mar 31, 2025	SIREN, L.L.C.	10.75%	38.92M	17.93M	0	0
Mar 31, 2024	AMERIPRISE FINANCIAL INC	0.64%	1.42M	3.4M	-472.25K	-24.98%
Mar 31, 2024	BVF INC/IL	0.76%	1.69M	4.05M	-22.75M	-93.10%
Mar 31, 2024	STATE STREET CORP	0.9%	1.99M	4.77M	95.19K	+5.03%
Mar 31, 2024	CITIGROUP INC	0.01%	17.55K	42.12K	-207.45K	-92.20%
Mar 31, 2024	SG AMERICAS SECURITIES, LLC	0.01%	19.27K	46K	-24.52K	-56.00%
Mar 31, 2024	PRINCIPAL SECURITIES, INC.	0.01%	20K	48K	-1.5K	-6.98%
Mar 31, 2024	TIAA TRUST, NATIONAL ASSOCIATION	0.01%	27.06K	64.94K	57	+0.21%
Mar 31, 2024	STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM	0.01%	29.4K	71.44K	5.34K	+22.18%
Mar 31, 2024	BBR PARTNERS, LLC	0.01%	30K	72K	30K	+100.00%
Mar 31, 2024	WELLS FARGO & COMPANY/MN	0.01%	31.02K	74.44K	4.28K	+16.01%
Mar 31, 2024	VICTORY CAPITAL MANAGEMENT INC	0.01%	31.37K	75.29K	-818	-2.54%
Mar 31, 2024	METLIFE INVESTMENT MANAGEMENT, LLC	0.01%	32.86K	78.87K	32.86K	+100.00%
Mar 31, 2024	NEW YORK STATE COMMON RETIREMENT FUND	0.02%	33.73K	81K	63	+0.19%
Mar 31, 2024	PROSHARE ADVISORS LLC	0.02%	33.75K	80.99K	2.76K	+8.92%
Mar 31, 2024	BALYASNY ASSET MANAGEMENT L.P.	0.02%	34.43K	82.64K	34.43K	+100.00%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.02%	35.55K	85.31K	17.33K	+95.09%
Mar 31, 2024	UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGMENT CO	0.02%	35.71K	86K	0	0
Mar 31, 2024	BANK OF MONTREAL /CAN/	0.02%	40K	87.6K	40K	+100.00%
Mar 31, 2024	WEDBUSH SECURITIES INC	0.02%	41.65K	100K	41.65K	+100.00%
Mar 31, 2024	KWB WEALTH	0.02%	40.64K	97.54K	0	0
Mar 31, 2024	AMERICAN INTERNATIONAL GROUP, INC.	0.02%	45.66K	109.58K	-391	-0.85%
Mar 31, 2024	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.02%	46.93K	113K	18.6K	+65.66%
Mar 31, 2024	RUSSELL INVESTMENTS GROUP, LTD.	0.02%	49.1K	117.84K	0	0
Mar 31, 2024	INVESCO LTD.	0.02%	49.82K	119.56K	-11.36K	-18.57%
Mar 31, 2024	CERITY PARTNERS LLC	0.01%	22.51K	54.03K	22.51K	+100.00%
Mar 31, 2024	NEA MANAGEMENT COMPANY, LLC	1.08%	2.38M	5.72M	0	0
Mar 31, 2024	ORBIMED ADVISORS LLC	1.6%	3.54M	8.5M	3.54M	+100.00%
Mar 31, 2024	DIMENSIONAL FUND ADVISORS LP	0.02%	49.94K	119.86K	49.94K	+100.00%
Mar 31, 2024	VANGUARD GROUP INC	2.89%	6.4M	15.36M	420.85K	+7.04%
Mar 31, 2024	BLACKROCK INC.	3.48%	7.69M	18.46M	688.12K	+9.82%
Mar 31, 2024	FMR LLC	6.28%	13.89M	33.35M	11.62M	+510.33%
Mar 31, 2024	JANE STREET GROUP, LLC	0.13%	281.59K	675.81K	9.22K	+3.39%
Mar 31, 2024	ARTAL GROUP S.A.	53.16%	117.55M	282.13M	0	0
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	1.08%	2.39M	5.73M	40.22K	+1.71%
Mar 31, 2024	LAZARD FRERES GESTION S.A.S.	0.02%	50K	119K	50K	+100.00%
Mar 31, 2024	PATHSTONE HOLDINGS, LLC	0.03%	62.73K	150.54K	28.28K	+82.10%
Mar 31, 2024	BARCLAYS PLC	0.03%	64.62K	155K	-62.4K	-49.13%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.04%	85.87K	206.09K	-124.85K	-59.25%
Mar 31, 2024	NATIXIS ADVISORS, L.P.	0.04%	86.09K	207K	86.09K	+100.00%
Mar 31, 2024	LPL FINANCIAL LLC	0.04%	89.96K	215.91K	45.97K	+104.49%
Mar 31, 2024	JPMORGAN CHASE & CO	0.04%	90.14K	216.33K	-2.95M	-97.04%
Mar 31, 2024	COMPAGNIE LOMBARD ODIER SCMA	0.04%	94K	225.6K	0	0
Mar 31, 2024	COMMONWEALTH EQUITY SERVICES, LLC	0.04%	95.18K	228K	95.18K	+100.00%
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	0.05%	105.32K	253K	4.62K	+4.59%
Mar 31, 2024	CITADEL ADVISORS LLC	0.05%	99.7K	239.28K	21.2K	+27.01%
Mar 31, 2024	RHUMBLINE ADVISERS	0.06%	134.85K	323.62K	4.55K	+3.50%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.07%	156.21K	374.91K	-79.13K	-33.62%
Mar 31, 2024	UBS GROUP AG	0.08%	166.96K	400.71K	-2.66K	-1.57%
Mar 31, 2024	TWO SIGMA INVESTMENTS, LP	0.09%	189.43K	454.63K	-13.46K	-6.63%
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	0.1%	219.94K	527.86K	-25.36K	-10.34%
Mar 31, 2024	BOULDER HILL CAPITAL MANAGEMENT LP	0.12%	256.4K	615.36K	256.4K	+100.00%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.13%	290.9K	698.16K	132.1K	+83.19%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.13%	292.01K	700.82K	-49.07K	-14.39%
Mar 31, 2024	VIRTUS ETF ADVISERS LLC	0.13%	293.09K	703.42K	42.17K	+16.81%
Mar 31, 2024	GSA CAPITAL PARTNERS LLP	0.13%	293.33K	704K	-486.74K	-62.40%
Mar 31, 2024	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.14%	319.06K	766K	319.06K	+100.00%
Mar 31, 2024	MARSHALL WACE, LLP	0.23%	499.17K	1.2M	499.17K	+100.00%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.24%	524.18K	1.26M	113.13K	+27.52%
Mar 31, 2024	MILLENNIUM MANAGEMENT LLC	0.24%	534.18K	1.28M	-1.1M	-67.29%
Mar 31, 2024	POINT72 ASSET MANAGEMENT, L.P.	0.26%	584.39K	1.4M	584.39K	+100.00%
Mar 31, 2024	WELLINGTON MANAGEMENT GROUP LLP	0.31%	686.42K	1.65M	686.42K	+100.00%
Mar 31, 2024	NORTHERN TRUST CORP	0.39%	866.56K	2.08M	6.97K	+0.81%
Mar 31, 2024	PINNACLE ASSOCIATES LTD	0.79%	1.75M	4.19M	17.01K	+0.98%
Mar 31, 2024	STIFEL FINANCIAL CORP	0.02%	52.17K	125.22K	12.52K	+31.58%
Mar 31, 2024	BNP PARIBAS ARBITRAGE, SNC	0.03%	59.38K	142.51K	26.86K	+82.59%
Mar 31, 2024	MORGAN STANLEY	0.11%	244.21K	586.1K	-673.48K	-73.39%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.4%	881.12K	2.11M	16.95K	+1.96%
Mar 31, 2024	SCHONFELD STRATEGIC ADVISORS LLC	0.43%	960.15K	5.35M	960.15K	+100.00%
Mar 31, 2024	CUBIST SYSTEMATIC STRATEGIES, LLC	0.64%	1.4M	3.37M	1.4M	+100.00%
Dec 31, 2023	TUDOR INVESTMENT CORP ET AL	0.02%	47.1K	72.07K	0	0
Dec 31, 2023	SIMPLEX TRADING, LLC	0.02%	54.25K	82K	54.25K	+100.00%
Dec 31, 2023	AMUNDI	0.02%	54.53K	80.71K	54.53K	+100.00%
Dec 31, 2023	INVESCO LTD.	0.03%	61.18K	93.61K	9.25K	+17.80%
Dec 31, 2023	CITADEL ADVISORS LLC	0.03%	78.5K	120.11K	2.7K	+3.56%
Dec 31, 2023	COMPAGNIE LOMBARD ODIER SCMA	0.04%	94K	143.82K	0	0
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	0.04%	100.69K	155K	0	0
Dec 31, 2023	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	0.04%	103.14K	157.81K	103.14K	+100.00%
Dec 31, 2023	BARCLAYS PLC	0.05%	127.02K	195K	87.83K	+224.11%
Dec 31, 2023	RHUMBLINE ADVISERS	0.05%	130.29K	199.34K	0	0
Dec 31, 2023	CIBC PRIVATE WEALTH GROUP, LLC	0.06%	150.1K	229.65K	150.1K	+100.00%
Dec 31, 2023	UBS GROUP AG	0.07%	169.62K	259.51K	44.25K	+35.30%
Dec 31, 2023	TWO SIGMA INVESTMENTS, LP	0.08%	202.89K	310.42K	-442.48K	-68.56%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.09%	210.73K	322.41K	46.25K	+28.12%
Dec 31, 2023	CITIGROUP INC	0.09%	225K	344.25K	188.98K	+524.73%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.1%	235.34K	360.07K	-124.37K	-34.58%
Dec 31, 2023	ALLIANCEBERNSTEIN L.P.	0.1%	245.3K	375.31K	0	0
Dec 31, 2023	VIRTUS ETF ADVISERS LLC	0.1%	250.92K	383.91K	129.21K	+106.16%
Dec 31, 2023	JANE STREET GROUP, LLC	0.11%	272.37K	416.72K	190.44K	+232.44%
Dec 31, 2023	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.12%	282.47K	432.18K	-54.6K	-16.20%
Dec 31, 2023		0.13%	323.97K	495.67K	323.97K	+100.00%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.14%	341.08K	521.85K	9.75K	+2.94%
Dec 31, 2023	NUVEEN ASSET MANAGEMENT, LLC	0.17%	411.05K	628.9K	1.87K	+0.46%
Dec 31, 2023	RENAISSANCE TECHNOLOGIES LLC	0.17%	412.18K	631K	139.92K	+51.39%
Dec 31, 2023	GSA CAPITAL PARTNERS LLP	0.32%	780.08K	1.19M	780.08K	+100.00%
Dec 31, 2023	NORTHERN TRUST CORP	0.35%	859.59K	1.32M	-291.23K	-25.31%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.35%	864.18K	1.32M	12.25K	+1.44%
Dec 31, 2023	MORGAN STANLEY	0.37%	917.69K	1.4M	678.07K	+282.98%
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	0.67%	1.63M	2.5M	-2.25M	-57.97%
Dec 31, 2023	PINNACLE ASSOCIATES LTD	0.71%	1.73M	2.65M	-182.05K	-9.52%
Dec 31, 2023	AMERIPRISE FINANCIAL INC	0.77%	1.89M	2.89M	675.52K	+55.61%
Dec 31, 2023	STATE STREET CORP	0.77%	1.89M	2.9M	16.18K	+0.86%
Dec 31, 2023	FMR LLC	0.93%	2.28M	3.48M	-5.29M	-69.90%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	0.96%	2.35M	3.59M	222.78K	+10.48%
Dec 31, 2023	NEA MANAGEMENT COMPANY, LLC	0.97%	2.38M	3.64M	0	0
Dec 31, 2023	JPMORGAN CHASE & CO	1.24%	3.04M	4.66M	228.26K	+8.11%
Dec 31, 2023	VANGUARD GROUP INC	2.44%	5.98M	9.15M	-419.84K	-6.56%
Dec 31, 2023	BLACKROCK INC.	2.86%	7.01M	10.72M	350.19K	+5.26%
Dec 31, 2023	BVF INC/IL	9.98%	24.44M	37.39M	4.44M	+22.21%
Dec 31, 2023	ARTAL GROUP S.A.	48%	117.55M	179.86M	0	0
Dec 31, 2023	D. E. SHAW & CO., INC.	0.15%	359.21K	549.59K	-424.91K	-54.19%
Dec 31, 2023	STIFEL FINANCIAL CORP	0.02%	39.65K	60.67K	-42.32K	-51.62%
Dec 31, 2023	DEUTSCHE BANK AG\	0.02%	40.29K	61.64K	0	0
Dec 31, 2023	KWB WEALTH	0.02%	40.64K	62.18K	40.64K	+100.00%
Dec 31, 2023	SG AMERICAS SECURITIES, LLC	0.02%	43.79K	67K	-14.91K	-25.40%
Dec 31, 2023	LPL FINANCIAL LLC	0.02%	43.99K	67.31K	17K	+62.98%
Dec 31, 2023	CAPTRUST FINANCIAL ADVISORS	0.02%	44.64K	68.29K	18	+0.04%
Dec 31, 2023	AMERICAN INTERNATIONAL GROUP, INC.	0.02%	46.05K	70.46K	-186	-0.40%
Dec 31, 2023	RUSSELL INVESTMENTS GROUP, LTD.	0.02%	49.1K	75.12K	0	0

Insiders

Among the LXRX insiders holding of 1.17% of the stake in company, ARTAL INTERNATIONAL S.C.A., , holds the largest shares of 78.63M. INVUS ADVISORS, L.L.C., , is the second largest LXRX insider with ownership of 50.86M shares. INVUS PUBLIC EQUITIES, L.P., , stands third with possession of 32.26M shares of that stake.

Insiders	Designation	Shares Held
ARTAL INTERNATIONAL S.C.A.		78.63M
INVUS ADVISORS, L.L.C.		50.86M
INVUS PUBLIC EQUITIES, L.P.		32.26M
INVUS US PARTNERS LLC		5.45M
DEBBANE RAYMOND	director	1.65M
INVUS GLOBAL MANAGEMENT, LLC		1.54M
COATS LONNEL	Chief Executive Officer	914.36K
WADE JEFFREY L	President and CFO	264.34K
SOBECKI CHRISTOPHER J	director	125.7K
TESSMER JAMES F	VP, Finance & Accounting	71.77K
MCDERMOTT WENDY	VP, Human Resources	28.48K
SANTINI ALEXANDER A	EVP and CCO	16.66K

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Feb 18, 2026	DEBBANE RAYMOND	PURCHASE	1.32	133.69K	176.47K	1.65M
Feb 17, 2026	DEBBANE RAYMOND	PURCHASE	1.31	76.86K	100.54K	1.52M
Feb 13, 2026	DEBBANE RAYMOND	PURCHASE	1.31	57.95K	75.88K	1.44M
Feb 02, 2026	INVUS GLOBAL MANAGEMENT, LLC	PURCHASE	1.30	1.54M	2M	1.54M
Nov 16, 2023	COATS LONNEL	PURCHASE	1.05	90K	94.8K	914.36K
Nov 10, 2023	COATS LONNEL	PURCHASE	1.01	10K	10.1K	824.36K
Oct 12, 2023	DEBBANE RAYMOND	PURCHASE	1.03	148.82K	153.81K	1.34M
Oct 11, 2023	DEBBANE RAYMOND	PURCHASE	1.08	342.87K	370.78K	1.19M
Oct 10, 2023	DEBBANE RAYMOND	PURCHASE	1.14	508.31K	579.37K	849.15K
Sep 14, 2023	WADE JEFFREY L	PURCHASE	1.38	10K	13.8K	264.34K
Aug 04, 2023	MCDERMOTT WENDY	PURCHASE	1.84	6K	11.04K	28.48K
Jun 29, 2023	COATS LONNEL	PURCHASE	2.16	10K	21.6K	814.36K
Jun 26, 2023	COATS LONNEL	PURCHASE	2.18	10K	21.79K	804.36K
Jun 23, 2023	COATS LONNEL	PURCHASE	2.50	10K	24.95K	794.36K
Jun 23, 2023	MCDERMOTT WENDY	PURCHASE	2.43	10K	24.3K	22.48K
Jun 22, 2023	COATS LONNEL	PURCHASE	2.31	40K	92.4K	784.36K
Jun 20, 2023	WADE JEFFREY L	PURCHASE	2.33	10K	23.35K	252.34K
Jun 05, 2023	ARTAL INTERNATIONAL S.C.A.	PURCHASE	2.60	27.78M	72.22M	78.63M
Aug 05, 2022	INVUS US PARTNERS LLC	PURCHASE	2.50	147.39K	368.48K	5.45M
Aug 05, 2022	INVUS ADVISORS, L.L.C.	PURCHASE	2.50	2.43M	6.07M	50.86M
Aug 05, 2022	DEBBANE RAYMOND	PURCHASE	2.50	147.39K	368.48K	5.45M
Aug 05, 2022	ARTAL INTERNATIONAL S.C.A.	PURCHASE	2.50	2.43M	6.07M	50.86M
Aug 01, 2022	ARTAL INTERNATIONAL S.C.A.	PURCHASE	2.50	16.17M	40.43M	48.43M
Aug 01, 2022	DEBBANE RAYMOND	PURCHASE	2.50	982.6K	2.46M	5.3M
Aug 01, 2022	INVUS US PARTNERS LLC	PURCHASE	2.50	982.6K	2.46M	5.3M
Aug 01, 2022	INVUS ADVISORS, L.L.C.	PURCHASE	2.50	16.17M	40.43M	48.43M
Mar 15, 2021	TESSMER JAMES F	SALE	6.92	12K	83.1K	71.77K
Dec 16, 2020	INVUS PUBLIC EQUITIES, L.P.	PURCHASE	3.20	10.94M	35M	32.26M
Dec 16, 2020	ARTAL INTERNATIONAL S.C.A.	PURCHASE	3.20	10.94M	35M	32.26M
Sep 18, 2019	COATS LONNEL	PURCHASE	3.10	50K	155K	227.54K
Sep 18, 2019	SANTINI ALEXANDER A	PURCHASE	3.23	2.5K	8.08K	16.66K
Sep 17, 2019	COATS LONNEL	PURCHASE	3.13	100	312.5	127.64K
Sep 16, 2019	SOBECKI CHRISTOPHER J	PURCHASE	2.54	100	253.5	125.7K
Sep 16, 2019	DEBBANE RAYMOND	PURCHASE	2.60	3.99K	10.37K	223.63K
Sep 13, 2019	DEBBANE RAYMOND	PURCHASE	2.25	200	450	13.1K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE1.81M4

SALES00

NET SHARES1.81M4

SHARES HELD6.16M4

% NET SHARES-70.65%0%

Frequently Asked Questions