How many institutions own LPTX stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own LPTX shares is 43, representing 22.06% of the company's common stock.

Who are the major shareholders selling Leap Therapeutics, Inc. stock?

JANE STREET GROUP, LLC, in the last quarter, reduced its stake in LPTX by -100% restricting it's holding to 0 shares of worth nearly -. TWO SIGMA ADVISERS, LP also lessened -100% of the LPTX shares from its portfolio, reducing its holding to 0 shares of worth -. ACADIAN ASSET MANAGEMENT LLC also shunned LPTX shares holding by -100% last quarter which brought its holding to 0 shares worth -.

Investors who are buying LPTX stock?

As per its latest 13F filing, CAITONG INTERNATIONAL ASSET MANAGEMENT CO., LTD increased its stake in LPTX by 100% in the last quarter. The institutional holder raised its holding to 38.19 thousand shares having worth more than $44.30K. CITIGROUP INC also added 100% more shares of LPTX to its portfolio, raising its holding to 73.02 thousand shares of worth $84.71K. MILLENNIUM MANAGEMENT LLC also increased its LPTX shares holding by 100% which brought its holding to 32.27 thousand shares worth $37.43K.

LPTX's major insiders: who are they?

The insider with the most stakes in LPTX is BeiGene, Ltd. , 10 percent owner at the company. Additionally, LPTX stock is highly held by 10 percent owner PERCEPTIVE ADVISORS LLC and CFO, GC, Treasurer & Secretary ONSI DOUGLAS E among others.

Did an insider recently sell LPTX stock?

Company executives, directors, and other insiders own 16.2% percent of Leap Therapeutics, Inc.'s stock. Within the last six months, there have been 0 transaction(s) in which LPTX insiders have sold stock, totaling 0 shares. Insiders that have sold shares include .

Which insider recently purchased LPTX stock?

There have been 0 transaction(s) during the past 6-months in which Leap Therapeutics, Inc. insiders have bought stock, totalling 0 shares

How much of LPTX does insiders own?

Around 0 Leap Therapeutics, Inc. shares are held by insiders, which represents about 16.2% of LPTX stock.

Who is the insider with the largest stake?

LPTX 10 percent owner, BeiGene, Ltd. holds the largest portfolio of the company's shares. LPTX shares owned by BeiGene, total nearly 7.35 million.

Which institution holds the most shares in LPTX?

CAITONG INTERNATIONAL ASSET MANAGEMENT CO., LTD is the largest institutional owner in LPTX which holds 38.19 thousand shares worth $44.30K or 0.09% of the total LPTX shares outstanding followed by JANE STREET GROUP, LLC with ownership of 0 shares representing 0% of the LPTX ownership. TWO SIGMA ADVISERS, LP is the third largest stakeholder with 0 shares or 0% of the ownership worth more than -.

Is Leap Therapeutics, Inc. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the LPTX is concerned, it is a stock which is optionable.

Is there a short position on LPTX's shares?

Number of LPTX shares short is 1.53M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding LPTX shares are there?

As of today, 41.44M shares of LPTX are outstanding.

Is there many float in LPTX stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, LPTX has 32.22M shares in float.

LPTX short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for LPTX is 3.97.

Leap Therapeutics (LPTX) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares3.68

Short Percent Of Float4.33

Shares Outstanding41.44M

Shares Float32.22M

Shares Short1.53M

Short Ratio3.97

4.33%

Short % of Float

3.68%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

16.2% Percentage of Shares held by All Insiders

22.06% Percentage of Shares held by All Institutions

26.33% Percentage of Float held by Institutions

Number of Institutions Holding Shares

Institutional Ownership

About 22.06% of LPTX shares are held by financial institutions. CAITONG INTERNATIONAL ASSET MANAGEMENT CO., LTD is the top corporate investor, holding 38.19K shares valued at $44.30K. A 0.09% stake in Leap Therapeutics, Inc. is owned by the company. JANE STREET GROUP, LLC owns 0 shares valued at -, which translates its holding of 0% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Dec 31, 2025	CAITONG INTERNATIONAL ASSET MANAGEMENT CO., LTD	0.09%	38.19K	44.3K	38.19K	+100.00%
Dec 31, 2025	JANE STREET GROUP, LLC	0%	0	-	-165.39K	-100.00%
Dec 31, 2025	TWO SIGMA ADVISERS, LP	0%	0	-	-99.68K	-100.00%
Dec 31, 2025	ACADIAN ASSET MANAGEMENT LLC	0%	0	-	-1.24M	-100.00%
Dec 31, 2025	GILEAD SCIENCES, INC.	0%	0	-	-5.32M	-100.00%
Dec 31, 2025	TOMPKINS FINANCIAL CORP	0%	120	139	0	0
Dec 31, 2025	CITIGROUP INC	0.18%	73.02K	84.71K	73.02K	+100.00%
Dec 31, 2025	HRT FINANCIAL LP	0%	0	-	-118.63K	-100.00%
Dec 31, 2025	MILLENNIUM MANAGEMENT LLC	0.08%	32.27K	37.43K	32.27K	+100.00%
Dec 31, 2025	SEQUOIA FINANCIAL ADVISORS, LLC	0.12%	48K	55.68K	48K	+100.00%
Dec 31, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.15%	62.49K	72.48K	62.49K	+100.00%
Dec 31, 2025	TWO SIGMA INVESTMENTS, LP	0.17%	72.17K	83.72K	1.32K	+1.87%
Dec 31, 2025	NORTHERN TRUST CORP	0.21%	87.56K	101.57K	25.96K	+42.13%
Dec 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.14%	59.8K	69.37K	47.6K	+390.16%
Dec 31, 2025	CNB BANK	0.01%	5K	5.8K	0	0
Dec 31, 2025	TOROSO INVESTMENTS, LLC	0.09%	35.31K	40.96K	35.31K	+100.00%
Dec 31, 2025	FORTITUDE FAMILY OFFICE, LLC	0%	182	211	182	+100.00%
Dec 31, 2025	IHT WEALTH MANAGEMENT, LLC	0.03%	11K	12.76K	11K	+100.00%
Dec 31, 2025	KEYSTONE FINANCIAL GROUP	0.03%	11.71K	13.59K	11.71K	+100.00%
Dec 31, 2025	UBS GROUP AG	0.08%	31.15K	36.13K	30.75K	+7,686.25%
Dec 31, 2025	LPL FINANCIAL LLC	0.08%	32.76K	38.01K	-3.25K	-9.01%
Dec 31, 2025	KEY CLIENT FIDUCIARY ADVISORS, LLC	0.2%	84.59K	98.12K	-53.37K	-38.69%
Dec 31, 2025	TEXAS CAPITAL BANK WEALTH MANAGEMENT SERVICES INC	0.25%	104.2K	120.87K	104.2K	+100.00%
Dec 31, 2025	STATE STREET CORP	0.34%	140.11K	162.53K	14.5K	+11.54%
Dec 31, 2025	XTX TOPCO LTD	0%	0	-	-30.66K	-100.00%
Dec 31, 2025	BAIRD FINANCIAL GROUP, INC.	0%	0	-	-20K	-100.00%
Dec 31, 2025	ALLWORTH FINANCIAL LP	0%	135	157	0	0
Dec 31, 2025	JPMORGAN CHASE & CO	0%	227	263	0	0
Dec 31, 2025	BANK OF AMERICA CORP /DE/	0%	453	526	-1.44M	-99.97%
Dec 31, 2025	MORGAN STANLEY	0%	486	563	-8	-1.62%
Dec 31, 2025	ADVISOR GROUP HOLDINGS, INC.	0%	1.85K	2.15K	-32	-1.70%
Dec 31, 2025	HIGHTOWER ADVISORS, LLC	0.12%	50.5K	58.58K	-1.05M	-95.43%
Dec 31, 2025	CITADEL ADVISORS LLC	0.1%	41K	47.56K	6.7K	+19.53%
Dec 31, 2025	SIMPLIFY ASSET MANAGEMENT INC.	4.52%	1.87M	2.17M	896.71K	+91.91%
Dec 31, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0.03%	12.61K	14.62K	12.61K	+100.00%
Dec 31, 2025	SIMPLEX TRADING, LLC	0.16%	67.82K	78.67K	62.77K	+1,243.20%
Dec 31, 2025	OPTIMA CAPITAL LLC	0%	798	926	798	+100.00%
Dec 31, 2025	HUNTINGTON NATIONAL BANK	0%	1K	1.16K	0	0
Dec 31, 2025	FARTHER FINANCE ADVISORS, LLC	0.01%	2.06K	2.39K	1.06K	+105.80%
Dec 31, 2025	ROYAL BANK OF CANADA	0.02%	9.88K	11K	9.88K	+100.00%
Dec 31, 2025	CETERA INVESTMENT ADVISERS	0.02%	10K	11.6K	10K	+100.00%
Dec 31, 2025	BLAIR WILLIAM & CO/IL	0.02%	10K	11.6K	0	0
Dec 31, 2025	GROUP ONE TRADING, L.P.	0.39%	161.58K	187.43K	157.77K	+4,137.58%
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.28%	530.19K	615.23K	218K	+69.83%
Dec 31, 2025	VANGUARD GROUP INC	5.13%	2.13M	2.47M	966.43K	+83.26%
Dec 31, 2025	BLACKROCK, INC.	5.65%	2.34M	2.72M	2.22M	+1,770.24%
Dec 31, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	0%	0	-	-25.83K	-100.00%
Sep 30, 2025	DRW SECURITIES, LLC	0%	0	-	-28.16K	-100.00%
Sep 30, 2025	HUNTINGTON NATIONAL BANK	0%	1K	454	0	0
Sep 30, 2025	CIBC PRIVATE WEALTH GROUP, LLC	0%	0	-	-1.5K	-100.00%
Sep 30, 2025	ALLWORTH FINANCIAL LP	0%	135	62	0	0
Sep 30, 2025	RAYMOND JAMES FINANCIAL INC	0%	0	-	-4.58K	-100.00%
Sep 30, 2025	MONACO ASSET MANAGEMENT SAM	0%	0	-	-1.05M	-100.00%
Sep 30, 2025	ADVISOR GROUP HOLDINGS, INC.	0%	1.88K	526	0	0
Sep 30, 2025	DAUNTLESS INVESTMENT GROUP, LLC	0%	0	-	-59.97K	-100.00%
Sep 30, 2025	KEY CLIENT FIDUCIARY ADVISORS, LLC	0.33%	137.96K	62.63K	-205.9K	-59.88%
Sep 30, 2025	XTX TOPCO LTD	0.07%	30.66K	13.92K	16.64K	+118.59%
Sep 30, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	0.06%	25.83K	11.73K	-14.1K	-35.30%
Sep 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.03%	12.2K	5.49K	-600	-4.69%
Sep 30, 2025	SIMPLEX TRADING, LLC	0.01%	5.05K	2K	-100	-1.94%
Sep 30, 2025	GROUP ONE TRADING, L.P.	0.01%	3.81K	1.73K	0	0
Sep 30, 2025	BAIRD FINANCIAL GROUP, INC.	0.05%	20K	9.08K	0	0
Sep 30, 2025	683 CAPITAL MANAGEMENT, LLC	0%	0	-	-1.44M	-100.00%
Sep 30, 2025	CITADEL ADVISORS LLC	0%	0	-	-74.93K	-100.00%
Sep 30, 2025	VIRTU FINANCIAL LLC	0%	0	-	-40.38K	-100.00%
Sep 30, 2025	FINANCIAL MANAGEMENT PROFESSIONALS, INC.	0%	0	-	-20	-100.00%
Sep 30, 2025	GILEAD SCIENCES, INC.	12.83%	5.32M	2.41M	0	0
Sep 30, 2025	BANK OF AMERICA CORP /DE/	3.49%	1.44M	655.79K	1.44M	+451,295.63%
Sep 30, 2025	ACADIAN ASSET MANAGEMENT LLC	2.98%	1.24M	560K	0	0
Sep 30, 2025	TOMPKINS FINANCIAL CORP	0%	120	54	0	0
Sep 30, 2025	CALDWELL SUTTER CAPITAL, INC.	0%	0	-	-4	-100.00%
Sep 30, 2025	BROKERS INTERNATIONAL FINANCIAL SERVICES, LLC.	0%	0	-	-44.21K	-100.00%
Sep 30, 2025	VANGUARD GROUP INC	2.8%	1.16M	526.95K	0	0
Sep 30, 2025	HIGHTOWER ADVISORS, LLC	2.67%	1.1M	501.6K	8K	+0.73%
Sep 30, 2025	SIMPLIFY ASSET MANAGEMENT INC.	2.35%	975.61K	442.93K	118.25K	+13.79%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.75%	312.19K	141.82K	0	0
Sep 30, 2025	JANE STREET GROUP, LLC	0.4%	165.39K	75.09K	165.39K	+100.00%
Sep 30, 2025	STATE STREET CORP	0.3%	125.61K	57.03K	0	0
Sep 30, 2025	BLACKROCK, INC.	0.3%	125.23K	56.86K	0	0
Sep 30, 2025	HRT FINANCIAL LP	0.29%	118.63K	53K	118.63K	+100.00%
Sep 30, 2025	TWO SIGMA ADVISERS, LP	0.24%	99.68K	45.26K	58.4K	+141.47%
Sep 30, 2025	TWO SIGMA INVESTMENTS, LP	0.17%	70.85K	32.17K	56.95K	+409.82%
Sep 30, 2025	NORTHERN TRUST CORP	0.15%	61.61K	27.97K	0	0
Sep 30, 2025	LPL FINANCIAL LLC	0.09%	36.01K	16.35K	-7.5K	-17.24%
Sep 30, 2025	FARTHER FINANCE ADVISORS, LLC	0%	1K	454	0	0
Sep 30, 2025	MORGAN STANLEY	0%	494	225	-140	-22.08%
Sep 30, 2025	UBS GROUP AG	0%	400	182	-121.8K	-99.67%
Sep 30, 2025	JPMORGAN CHASE & CO	0%	227	103	0	0
Sep 30, 2025	BLAIR WILLIAM & CO/IL	0.02%	10K	4.54K	0	0
Sep 30, 2025	CNB BANK	0.01%	5K	2.27K	0	0
Jun 30, 2025	CNB BANK	0.01%	5K	1.49K	2K	+66.67%
Jun 30, 2025	RAYMOND JAMES FINANCIAL INC	0.01%	4.58K	1.36K	4.58K	+100.00%
Jun 30, 2025	GROUP ONE TRADING, L.P.	0.01%	3.81K	1.13K	500	+15.09%
Jun 30, 2025	TWO SIGMA ADVISERS, LP	0.1%	41.28K	12.26K	41.28K	+100.00%
Jun 30, 2025	DRW SECURITIES, LLC	0.07%	28.16K	8.36K	0	0
Jun 30, 2025	BAIRD FINANCIAL GROUP, INC.	0.05%	20K	5.94K	0	0
Jun 30, 2025	XTX TOPCO LTD	0.03%	14.03K	4.17K	14.03K	+100.00%
Jun 30, 2025	LPL FINANCIAL LLC	0.11%	43.51K	12.92K	-9.85K	-18.46%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0%	320	95	61	+23.55%
Jun 30, 2025	BROKERS INTERNATIONAL FINANCIAL SERVICES, LLC.	0.11%	44.21K	13.13K	15K	+51.36%
Jun 30, 2025	ADVISOR GROUP HOLDINGS, INC.	0%	1.88K	545	0	0
Jun 30, 2025	FINANCIAL MANAGEMENT PROFESSIONALS, INC.	0%	20	6	0	0
Jun 30, 2025	CALDWELL SUTTER CAPITAL, INC.	0%	4	1	0	0
Jun 30, 2025	VIRTU FINANCIAL LLC	0.1%	40.38K	12K	40.38K	+100.00%
Jun 30, 2025	GILEAD SCIENCES, INC.	12.89%	5.32M	1.58M	0	0
Jun 30, 2025	683 CAPITAL MANAGEMENT, LLC	3.5%	1.44M	428.77K	-5.76K	-0.40%
Jun 30, 2025	NORTHERN TRUST CORP	0.15%	61.61K	18.29K	0	0
Jun 30, 2025	UBS GROUP AG	0.3%	122.2K	36.29K	13.8K	+12.73%
Jun 30, 2025	SIMPLIFY ASSET MANAGEMENT INC.	2.08%	857.36K	254.55K	-93.61K	-9.84%
Jun 30, 2025	JPMORGAN CHASE & CO	0%	227	67	0	0
Jun 30, 2025	ALLWORTH FINANCIAL LP	0%	135	41	20	+17.39%
Jun 30, 2025	MONACO ASSET MANAGEMENT SAM	2.54%	1.05M	311.75K	0	0
Jun 30, 2025	HIGHTOWER ADVISORS, LLC	2.66%	1.1M	325.66K	1.05M	+2,071.98%
Jun 30, 2025	VANGUARD GROUP INC	2.81%	1.16M	344.72K	-14.92K	-1.27%
Jun 30, 2025	ACADIAN ASSET MANAGEMENT LLC	3%	1.24M	365K	-43.42K	-3.39%
Jun 30, 2025	DAUNTLESS INVESTMENT GROUP, LLC	0.15%	59.97K	17.8K	59.97K	+100.00%
Jun 30, 2025	BARCLAYS PLC	0%	0	-	-28.82K	-100.00%
Jun 30, 2025	ROYAL BANK OF CANADA	0%	0	-	-2.74K	-100.00%
Jun 30, 2025	NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO	0%	0	-	-1.5K	-100.00%
Jun 30, 2025	BAKER BROS. ADVISORS LP	0%	0	-	-404.74K	-100.00%
Jun 30, 2025	LAURION CAPITAL MANAGEMENT LP	0%	0	-	-709.22K	-100.00%
Jun 30, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	0.1%	39.93K	11.85K	-71.08K	-64.03%
Jun 30, 2025	HUNTINGTON NATIONAL BANK	0%	1K	297	0	0
Jun 30, 2025	FARTHER FINANCE ADVISORS, LLC	0%	1K	297	0	0
Jun 30, 2025	MORGAN STANLEY	0%	634	188	-571	-47.39%
Jun 30, 2025		0.15%	59.97K	17.8K	59.97K	+100.00%
Jun 30, 2025	CIBC PRIVATE WEALTH GROUP, LLC	0%	1.5K	445	0	0
Jun 30, 2025	TOMPKINS FINANCIAL CORP	0%	120	36	0	0
Jun 30, 2025	CITADEL ADVISORS LLC	0%	0	-	-30.4K	-100.00%
Jun 30, 2025	JANE STREET GROUP, LLC	0%	0	-	-32.96K	-100.00%
Jun 30, 2025	KEY CLIENT FIDUCIARY ADVISORS, LLC	0.83%	343.86K	102.09K	-44.86K	-11.54%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.76%	312.19K	92.74K	8.08K	+2.66%
Jun 30, 2025	STATE STREET CORP	0.3%	125.61K	37.3K	0	0
Jun 30, 2025	BLACKROCK, INC.	0.3%	125.23K	37.18K	-76.43K	-37.90%
Jun 30, 2025	TWO SIGMA INVESTMENTS, LP	0.03%	13.9K	4.13K	1.06K	+8.25%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.03%	12.8K	3.84K	-1.4K	-9.86%
Jun 30, 2025	BLAIR WILLIAM & CO/IL	0.02%	10K	2.97K	0	0
Jun 30, 2025	SIMPLEX TRADING, LLC	0.01%	5.15K	1K	5.15K	+100.00%
Mar 31, 2025	GILEAD SCIENCES, INC.	12.89%	5.32M	1.62M	0	0
Mar 31, 2025	NORTHERN TRUST CORP	0.15%	61.61K	18.8K	0	0
Mar 31, 2025	HIGHTOWER ADVISORS, LLC	0.12%	50.5K	15.41K	-2K	-3.81%
Mar 31, 2025	DIMENSIONAL FUND ADVISORS LP	0%	0	-	-100.17K	-100.00%
Mar 31, 2025	GROUP ONE TRADING, L.P.	0.01%	3.31K	1.01K	-329	-9.03%
Mar 31, 2025	CNB BANK	0.01%	3K	915	3K	+100.00%
Mar 31, 2025	US BANCORP \DE\	0%	0	-	-610	-100.00%
Mar 31, 2025	683 CAPITAL MANAGEMENT, LLC	3.51%	1.45M	442.36K	99.9K	+7.40%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.74%	304.11K	92.85K	-27.3K	-8.24%
Mar 31, 2025	BLACKROCK, INC.	0.49%	201.67K	61.53K	-25.36K	-11.17%
Mar 31, 2025	CITADEL ADVISORS LLC	0.07%	30.4K	9.28K	18.8K	+162.07%
Mar 31, 2025	BROKERS INTERNATIONAL FINANCIAL SERVICES, LLC.	0.07%	29.21K	8.91K	29.21K	+100.00%
Mar 31, 2025	DRW SECURITIES, LLC	0.07%	28.16K	8.59K	28.16K	+100.00%
Mar 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.03%	14.2K	4.4K	14.2K	+100.00%
Mar 31, 2025	MORGAN STANLEY	0%	1.21K	367	-207	-14.66%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0%	259	79	13	+5.28%
Mar 31, 2025	ALLWORTH FINANCIAL LP	0%	115	46	0	0
Mar 31, 2025	SIMPLIFY ASSET MANAGEMENT INC.	2.3%	950.97K	290.14K	4.93K	+0.52%
Mar 31, 2025	LAURION CAPITAL MANAGEMENT LP	1.72%	709.22K	216.38K	0	0
Mar 31, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	0.27%	111K	33.87K	5K	+4.72%
Mar 31, 2025	UBS GROUP AG	0.26%	108.41K	33.06K	74.87K	+223.27%
Mar 31, 2025	JANE STREET GROUP, LLC	0.08%	32.96K	10.06K	-4.14K	-11.17%
Mar 31, 2025	BARCLAYS PLC	0.07%	28.82K	9K	28.82K	+100.00%
Mar 31, 2025	FARTHER FINANCE ADVISORS, LLC	0%	1K	291	1K	+100.00%
Mar 31, 2025	JPMORGAN CHASE & CO	0%	227	69	0	0
Mar 31, 2025	HUNTINGTON NATIONAL BANK	0%	1K	305	1K	+100.00%
Mar 31, 2025	TOMPKINS FINANCIAL CORP	0%	120	37	0	0
Mar 31, 2025	TWO SIGMA INVESTMENTS, LP	0.03%	12.84K	3.92K	12.84K	+100.00%
Mar 31, 2025	NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO	0%	1.5K	458	1.5K	+100.00%
Mar 31, 2025	NEWEDGE ADVISORS, LLC	0%	82	25	-49.96K	-99.84%
Mar 31, 2025	WARBERG ASSET MANAGEMENT LLC	0.04%	15K	4.58K	15K	+100.00%
Mar 31, 2025	BLAIR WILLIAM & CO/IL	0.02%	10K	3.05K	0	0
Mar 31, 2025	ROYAL BANK OF CANADA	0.01%	2.74K	1K	-3.88K	-58.55%
Mar 31, 2025	ADVISOR GROUP HOLDINGS, INC.	0%	1.88K	582	-2.13K	-53.03%
Mar 31, 2025	BAKER BROS. ADVISORS LP	0.98%	404.74K	123.49K	-767.43K	-65.47%
Mar 31, 2025	CALDWELL SUTTER CAPITAL, INC.	0%	4	1	0	0
Mar 31, 2025	ACADIAN ASSET MANAGEMENT LLC	3.1%	1.28M	389K	1.06M	+470.43%
Mar 31, 2025	LPL FINANCIAL LLC	0.13%	53.36K	16.28K	-22.44K	-29.60%
Mar 31, 2025	FINANCIAL MANAGEMENT PROFESSIONALS, INC.	0%	20	6	20	+100.00%
Mar 31, 2025	CIBC PRIVATE WEALTH GROUP, LLC	0%	1.5K	402	0	0
Mar 31, 2025	VANGUARD GROUP INC	2.85%	1.18M	358.56K	-15.39K	-1.29%
Mar 31, 2025	MONACO ASSET MANAGEMENT SAM	2.54%	1.05M	320.36K	844.13K	+410.02%
Mar 31, 2025	KEY CLIENT FIDUCIARY ADVISORS, LLC	0.94%	388.72K	118.6K	27.47K	+7.60%
Mar 31, 2025	STATE STREET CORP	0.3%	125.61K	38.33K	0	0
Mar 31, 2025	SCIENTECH RESEARCH LLC	0.05%	20.74K	6.33K	20.74K	+100.00%
Mar 31, 2025	BAIRD FINANCIAL GROUP, INC.	0.05%	20K	6.1K	-8.9K	-30.80%
Mar 31, 2025	AMERICAN CENTURY COMPANIES INC	0%	0	-	-18.27K	-100.00%
Mar 31, 2025	SAMSARA BIOCAPITAL, LLC	5.92%	2.44M	745.16K	0	0
Mar 31, 2023	MILLENNIUM MANAGEMENT LLC	0.01%	12.67K	4K	-1.09M	-98.85%
Mar 31, 2023	BAYSTATE WEALTH MANAGEMENT LLC	0.01%	15.39K	5.23K	0	0
Mar 31, 2023	VALEO FINANCIAL ADVISORS, LLC	0.01%	15.64K	5.32K	0	0
Mar 31, 2023	CNB BANK	0.01%	16K	5.44K	0	0
Mar 31, 2023	ROCKEFELLER CAPITAL MANAGEMENT L.P.	0.01%	17K	5K	17K	+100.00%
Mar 31, 2023	GROUP ONE TRADING, L.P.	0.02%	21.24K	7.22K	-4.9K	-18.75%
Mar 31, 2023	JANNEY MONTGOMERY SCOTT LLC	0.02%	25K	8K	0	0
Mar 31, 2023	ANNANDALE CAPITAL, LLC	0.03%	40K	14K	0	0
Mar 31, 2023	TWO SIGMA INVESTMENTS, LP	0.03%	39.79K	13.53K	-58.28K	-59.43%
Mar 31, 2023	BANK OF NEW YORK MELLON CORP	0.03%	35.48K	12.06K	0	0
Mar 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.02%	32K	10.88K	0	0
Mar 31, 2023	RAYMOND JAMES & ASSOCIATES	0.02%	29.68K	10.09K	-4K	-11.88%
Mar 31, 2023	TWO SIGMA ADVISERS, LP	0.02%	27.4K	9.32K	-268.1K	-90.73%
Mar 31, 2023	UBS GROUP AG	0.01%	13.06K	4.44K	3.06K	+30.64%
Mar 31, 2023	RAYMOND JAMES FINANCIAL SERVICES ADVISORS, INC.	0.01%	12.88K	4.38K	12.88K	+100.00%
Mar 31, 2023	STATE STREET CORP	0.14%	177.74K	60.43K	0	0
Mar 31, 2023	US BANCORP \DE\	0%	6.1K	2.07K	0	0
Mar 31, 2023	BAKER BROS. ADVISORS LP	5.74%	7.43M	2.52M	6.87M	+1,226.69%
Mar 31, 2023	PERCEPTIVE ADVISORS LLC	5.2%	6.73M	2.29M	0	0
Mar 31, 2023	VANGUARD GROUP INC	2.48%	3.21M	1.09M	0	0
Mar 31, 2023	LPL FINANCIAL LLC	0.02%	26.38K	8.97K	-1.25K	-4.52%
Mar 31, 2023	PLATINUM INVESTMENT MANAGEMENT LTD	0.2%	264.41K	89.9K	-1.06M	-80.09%
Mar 31, 2023	SCHONFELD STRATEGIC ADVISORS LLC	0.04%	50.7K	17.24K	-2.4K	-4.52%
Mar 31, 2023	NORTHERN TRUST CORP	0.12%	152.93K	52K	26.37K	+20.84%
Mar 31, 2023	CITADEL ADVISORS LLC	0.02%	21.5K	7.31K	-2K	-8.51%
Mar 31, 2023	ADAGE CAPITAL PARTNERS GP, L.L.C.	1.56%	2.01M	684.14K	1.21M	+151.52%
Mar 31, 2023	ADVISOR GROUP HOLDINGS, INC.	0.14%	183.9K	62.52K	1.97K	+1.08%
Mar 31, 2023	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.01%	14.97K	5.09K	-15.34K	-50.61%
Mar 31, 2023	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.23%	298.3K	101.42K	0	0
Mar 31, 2023	UBS OCONNOR LLC	0.81%	1.05M	356.55M	1.05M	+100.00%
Mar 31, 2023	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	0.35%	453.44K	155K	453.44K	+100.00%
Mar 31, 2023	ARTAL GROUP S.A.	3.09%	4M	1.36M	0	0
Mar 31, 2023	ROCK SPRINGS CAPITAL MANAGEMENT LP	3.6%	4.66M	1.58M	995.34K	+27.20%
Mar 31, 2023	CORMORANT ASSET MANAGEMENT, LP	1.15%	1.48M	504K	1.48M	+100.00%
Mar 31, 2023	KEY CLIENT FIDUCIARY ADVISORS, LLC	1.19%	1.54M	522.18K	186.5K	+13.82%
Mar 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	1.19%	1.54M	523K	1.54M	+100.00%
Mar 31, 2023	683 CAPITAL MANAGEMENT, LLC	2.16%	2.8M	952K	50K	+1.82%
Mar 31, 2023	MCADAM, LLC	0.04%	45.78K	15.57K	12.99K	+39.64%
Mar 31, 2023	COMMUNITY TRUST & INVESTMENT CO	0.01%	13.65K	4.64K	0	0
Mar 31, 2023	CAPTRUST FINANCIAL ADVISORS	0.01%	10K	3.4K	10K	+100.00%
Mar 31, 2023	DONALDSON CAPITAL MANAGEMENT, LLC	0.01%	10K	3.4K	0	0
Mar 31, 2023	RENAISSANCE TECHNOLOGIES LLC	0.35%	455.2K	155K	-470.5K	-50.83%
Mar 31, 2023	KNOTT DAVID M JR	0.43%	557.94K	190K	-282.06K	-33.58%
Mar 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	0.48%	618.67K	210.35K	0	0
Mar 31, 2023	BLACKROCK INC.	0.48%	619.01K	210.46K	5.56K	+0.91%
Mar 31, 2023	SAMSARA BIOCAPITAL, LLC	0.65%	846.04K	287.65K	846.04K	+100.00%
Mar 31, 2023	JANE STREET GROUP, LLC	0.01%	10.01K	3.4K	-171.16K	-94.48%
Mar 31, 2023	MORGAN STANLEY	0.01%	10.33K	3.51K	414	+4.17%
Mar 31, 2023	D.A. DAVIDSON & CO.	0.01%	11K	3.74K	11K	+100.00%

Insiders

Among the LPTX insiders holding of 16.2% of the stake in company, BEIGENE, LTD., 10 percent owner, holds the largest shares of 7.35M. PERCEPTIVE ADVISORS LLC, 10 percent owner, is the second largest LPTX insider with ownership of 3.51M shares. ONSI DOUGLAS E, CFO, GC, Treasurer & Secretary, stands third with possession of 592.8K shares of that stake.

Insiders	Designation	Shares Held
BEIGENE, LTD.	10 percent owner	7.35M
PERCEPTIVE ADVISORS LLC	10 percent owner	3.51M
ONSI DOUGLAS E	CFO, GC, Treasurer & Secretary	592.8K
MIRABELLI CHRISTOPHER	CEO, President, Chairman	592.8K
LAWLOR AUGUSTINE	Chief Operating Officer	592.8K
HEALTHCARE VENTURES IX, L.P.	10 percent owner	571.43K

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Sep 24, 2021	BEIGENE, LTD.	PURCHASE	2.85	2.54M	7.25M	7.35M
Sep 24, 2021	PERCEPTIVE ADVISORS LLC	PURCHASE	0.00	3.51M	3.51K	3.51M
Jun 22, 2020	PERCEPTIVE ADVISORS LLC	PURCHASE	2.00	1.75M	3.5M	8.48M
Feb 05, 2019	HEALTHCARE VENTURES IX, L.P.	PURCHASE	1.95	571.43K	1.11M	571.43K
Feb 05, 2019	ONSI DOUGLAS E	PURCHASE	1.95	571.43K	1.11M	592.8K
Feb 05, 2019	MIRABELLI CHRISTOPHER	PURCHASE	1.75	571.43K	1M	592.8K
Feb 05, 2019	LAWLOR AUGUSTINE	PURCHASE	1.95	571.43K	1.11M	592.8K
Nov 14, 2017	LAWLOR AUGUSTINE	PURCHASE	6.08	1.06M	6.44M	1.06M
Nov 14, 2017	MIRABELLI CHRISTOPHER	PURCHASE	6.08	1.06M	6.44M	1.06M
Nov 14, 2017	HEALTHCARE VENTURES IX, L.P.	PURCHASE	6.08	1.06M	6.44M	1.06M
Nov 14, 2017	ONSI DOUGLAS E	PURCHASE	6.08	1.06M	6.44M	1.06M

Frequently Asked Questions