How many institutions own KROS stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own KROS shares is 201, representing 100.64% of the company's common stock.

Who are the major shareholders selling Keros Therapeutics, Inc. stock?

METLIFE INVESTMENT MANAGEMENT, LLC, in the last quarter, reduced its stake in KROS by -15.53% restricting it's holding to 16.68 thousand shares of worth nearly $339.65K. MORGAN STANLEY also lessened -41.66% of the KROS shares from its portfolio, reducing its holding to 230.49 thousand shares of worth $4.69M. FRANKLIN RESOURCES INC also shunned KROS shares holding by -68.57% last quarter which brought its holding to 27.58 thousand shares worth $561.57K.

Investors who are buying KROS stock?

As per its latest 13F filing, EMPOWERED FUNDS, LLC increased its stake in KROS by 100% in the last quarter. The institutional holder raised its holding to 60.08 thousand shares having worth more than $1.22B. TUDOR INVESTMENT CORP ET AL also added 44.98% more shares of KROS to its portfolio, raising its holding to 28.31 thousand shares of worth $576.33K. BRIDGEWAY CAPITAL MANAGEMENT, LLC also increased its KROS shares holding by 100% which brought its holding to 60.08 thousand shares worth $1.22M.

KROS's major insiders: who are they?

The insider with the most stakes in KROS is Seehra Jasbir , CHIEF EXECUTIVE OFFICER at the company. Additionally, KROS stock is highly held by director Knowles Julius and director ORBIMED ADVISORS LLC among others.

Did an insider recently sell KROS stock?

Company executives, directors, and other insiders own 2.73% percent of Keros Therapeutics, Inc.'s stock. Within the last six months, there have been 6 transaction(s) in which KROS insiders have sold stock, totaling 918.99K shares. Insiders that have sold shares include SEEHRA JASBIR, LERNER LORENA RAQUEL, and REGNANTE KEITH.

Which insider recently purchased KROS stock?

There have been 0 transaction(s) during the past 6-months in which Keros Therapeutics, Inc. insiders have bought stock, totalling 0 shares

How much of KROS does insiders own?

Around 495.85K Keros Therapeutics, Inc. shares are held by insiders, which represents about 2.73% of KROS stock.

Who is the insider with the largest stake?

KROS CHIEF EXECUTIVE OFFICER, Seehra Jasbir holds the largest portfolio of the company's shares. KROS shares owned by Seehra total nearly 385.71 thousand.

Which institution holds the most shares in KROS?

METLIFE INVESTMENT MANAGEMENT, LLC is the largest institutional owner in KROS which holds 16.68 thousand shares worth $339.65K or 0.04% of the total KROS shares outstanding followed by MORGAN STANLEY with ownership of 230.49 thousand shares representing 0.57% of the KROS ownership. EMPOWERED FUNDS, LLC is the third largest stakeholder with 60.08 thousand shares or 0.15% of the ownership worth more than $1.22B.

Is Keros Therapeutics, Inc. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the KROS is concerned, it is a stock which is optionable.

Is there a short position on KROS's shares?

Number of KROS shares short is 4.84M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding KROS shares are there?

As of today, 40.62M shares of KROS are outstanding.

Is there many float in KROS stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, KROS has 27.23M shares in float.

KROS short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for KROS is 10.81.

Keros Therapeutics (KROS) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares11.92

Short Percent Of Float18.67

Shares Outstanding40.62M

Shares Float27.23M

Shares Short4.84M

Short Ratio10.81

18.67%

Short % of Float

11.92%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

2.73% Percentage of Shares held by All Insiders

100.64% Percentage of Shares held by All Institutions

103.46% Percentage of Float held by Institutions

201

Number of Institutions Holding Shares

Institutional Ownership

About 100.64% of KROS shares are held by financial institutions. METLIFE INVESTMENT MANAGEMENT, LLC is the top corporate investor, holding 16.68K shares valued at $339.65K. A 0.04% stake in Keros Therapeutics, Inc. is owned by the company. MORGAN STANLEY owns 230.49K shares valued at $4.69M, which translates its holding of 0.57% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Dec 31, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.04%	16.68K	339.65K	-3.07K	-15.53%
Dec 31, 2025	MORGAN STANLEY	0.57%	230.49K	4.69M	-164.61K	-41.66%
Dec 31, 2025	EMPOWERED FUNDS, LLC	0.15%	60.08K	1.22B	60.08K	+100.00%
Dec 31, 2025	TUDOR INVESTMENT CORP ET AL	0.07%	28.31K	576.33K	8.78K	+44.98%
Dec 31, 2025	FRANKLIN RESOURCES INC	0.07%	27.58K	561.57K	-60.18K	-68.57%
Dec 31, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.15%	60.08K	1.22M	60.08K	+100.00%
Dec 31, 2025	DIMENSIONAL FUND ADVISORS LP	0.14%	58.01K	1.18M	22.06K	+61.34%
Dec 31, 2025	AMERICAN CENTURY COMPANIES INC	0.09%	36.64K	745.99K	-2.53K	-6.45%
Dec 31, 2025	WELLS FARGO & COMPANY/MN	0.08%	32.76K	667.03K	6.87K	+26.54%
Dec 31, 2025	QUEST PARTNERS LLC	0.08%	32.09K	653.35K	16.84K	+110.44%
Dec 31, 2025	CAMBRIA INVESTMENT MANAGEMENT, L.P.	0.08%	31.31K	637.51K	31.31K	+100.00%
Dec 31, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.07%	30.28K	616.5K	-13.79K	-31.28%
Dec 31, 2025	STRS OHIO	0.07%	29.3K	596.55K	1.1K	+3.90%
Dec 31, 2025	NANTAHALA CAPITAL MANAGEMENT, LLC	0.62%	250K	5.09M	0	0
Dec 31, 2025	MILLENNIUM MANAGEMENT LLC	0.54%	220.21K	4.48M	166.86K	+312.79%
Dec 31, 2025	JACOBS LEVY EQUITY MANAGEMENT, INC	1.89%	768.43K	15.65M	161.34K	+26.58%
Dec 31, 2025	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.79%	321.35K	6.54M	-13.81K	-4.12%
Dec 31, 2025	DEUTSCHE BANK AG\	0.48%	195.28K	3.98M	172.02K	+739.59%
Dec 31, 2025	AQR CAPITAL MANAGEMENT LLC	0.44%	180.54K	3.68M	-23.81K	-11.65%
Dec 31, 2025	TWO SIGMA ADVISERS, LP	0.42%	171.8K	3.5M	117.6K	+216.97%
Dec 31, 2025	JANE STREET GROUP, LLC	0.4%	162.01K	3.3M	-446	-0.27%
Dec 31, 2025	BESSEMER GROUP INC	0.35%	143.85K	2.93M	143.85K	+100.00%
Dec 31, 2025	PANAGORA ASSET MANAGEMENT INC	0.3%	122.82K	2.5M	92.36K	+303.21%
Dec 31, 2025	NUVEEN, LLC	0.16%	63.1K	1.28M	-12.76K	-16.82%
Dec 31, 2025	BLACKROCK, INC.	5.64%	2.29M	46.64M	-426.62K	-15.70%
Dec 31, 2025	VANGUARD GROUP INC	3.75%	1.53M	31.06M	-1.19M	-43.90%
Dec 31, 2025	STATE STREET CORP	2.65%	1.08M	21.91M	-226.99K	-17.42%
Dec 31, 2025	MARINER, LLC	0.04%	15.21K	309.66K	-497	-3.16%
Dec 31, 2025	ABACUS WEALTH PARTNERS, LLC	0.03%	14.11K	287.26K	14.11K	+100.00%
Dec 31, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.03%	13.27K	270.08K	-3.41K	-20.44%
Dec 31, 2025	PROFUND ADVISORS LLC	0.03%	11.48K	233.79K	11.48K	+100.00%
Dec 31, 2025	ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	3.29%	1.33M	27.17M	1.08M	+415.75%
Dec 31, 2025	MADISON AVENUE PARTNERS, LP	2.03%	823.71K	16.77M	-1.88M	-69.58%
Dec 31, 2025	ORBIMED ADVISORS LLC	1.98%	804.21K	16.37M	-214.52K	-21.06%
Dec 31, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	1.93%	783.92K	15.96M	480.8K	+158.61%
Dec 31, 2025	D. E. SHAW & CO., INC.	1.86%	755.47K	15.38M	-575.95K	-43.26%
Dec 31, 2025	INVESCO LTD.	0.22%	87.43K	1.78M	12.45K	+16.60%
Dec 31, 2025	RBF CAPITAL, LLC	0.2%	81.72K	1.66M	-68.28K	-45.52%
Dec 31, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0.2%	80.77K	1.64M	-12.27K	-13.18%
Dec 31, 2025	BARCLAYS PLC	0.18%	74.73K	1.52M	-24.37K	-24.60%
Dec 31, 2025	ENGINEERS GATE MANAGER LP	0.15%	62.37K	1.27M	36K	+136.52%
Dec 31, 2025	FEDERATED HERMES, INC.	1.61%	654.72K	13.33M	140.56K	+27.34%
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.56%	635.21K	12.94M	-202.16K	-24.14%
Dec 31, 2025	RENAISSANCE TECHNOLOGIES LLC	1.46%	591.69K	12.05M	436.99K	+282.47%
Dec 31, 2025	GOLDMAN SACHS GROUP INC	1.45%	590.52K	12.02M	-734.97K	-55.45%
Dec 31, 2025	TWO SIGMA INVESTMENTS, LP	0.78%	318.44K	6.48M	235.92K	+285.88%
Dec 31, 2025	HRT FINANCIAL LP	0.64%	260.89K	5.31M	218.09K	+509.57%
Dec 31, 2025	WEISS ASSET MANAGEMENT LP	0.63%	254.06K	5.17M	254.06K	+100.00%
Dec 31, 2025	NORTHERN TRUST CORP	0.62%	250.57K	5.1M	-82.19K	-24.70%
Dec 31, 2025	CITADEL ADVISORS LLC	0.5%	203.4K	4.14M	156.6K	+334.62%
Dec 31, 2025	ALGERT GLOBAL LLC	0.48%	193.61K	3.94M	145.83K	+305.21%
Dec 31, 2025	MAN GROUP PLC	0.47%	190.21K	3.87M	-2.65K	-1.37%
Dec 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.46%	186.78K	3.8M	-105.23K	-36.04%
Dec 31, 2025	AMERIPRISE FINANCIAL INC	0.3%	122.83K	2.5M	2.4K	+1.99%
Dec 31, 2025	BANK OF NEW YORK MELLON CORP	0.3%	121.58K	2.48M	10.7K	+9.65%
Dec 31, 2025	Y-INTERCEPT (HONG KONG) LTD	0.29%	117.36K	2.39M	68.82K	+141.76%
Dec 31, 2025	PDT PARTNERS, LLC	0.28%	112.18K	2.28M	-220.63K	-66.29%
Dec 31, 2025	BANK OF AMERICA CORP /DE/	0.25%	100.11K	2.04M	-126.01K	-55.73%
Dec 31, 2025	SG AMERICAS SECURITIES, LLC	0.24%	98.7K	2.01M	92.21K	+1,420.61%
Dec 31, 2025	UBS GROUP AG	0.24%	97.08K	1.98M	-6.78K	-6.53%
Dec 31, 2025	RANGELEY CAPITAL, LLC	0.24%	96.8K	1.97M	-161.82K	-62.57%
Dec 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.43%	175.8K	3.58M	-41.7K	-19.17%
Dec 31, 2025	JUMP FINANCIAL, LLC	0.4%	161.14K	3.28M	161.14K	+100.00%
Dec 31, 2025	NOMURA HOLDINGS INC	0.39%	156.75K	3.19M	156.75K	+100.00%
Dec 31, 2025	GSA CAPITAL PARTNERS LLP	0.13%	51.35K	1.05M	26.05K	+102.95%
Dec 31, 2025	RHUMBLINE ADVISERS	0.11%	44.24K	900.62M	-6.24K	-12.37%
Dec 31, 2025	MASSACHUSETTS FINANCIAL SERVICES CO /MA/	0.11%	43.7K	889.63K	43.7K	+100.00%
Dec 31, 2025	HUSSMAN STRATEGIC ADVISORS, INC.	0.1%	42K	855.12K	42K	+100.00%
Dec 31, 2025	MARTINGALE ASSET MANAGEMENT L P	0.1%	39.38K	801.76K	202	+0.52%
Dec 31, 2025	LOS ANGELES CAPITAL MANAGEMENT LLC	0.08%	33.77K	507.58K	-3.23K	-8.73%
Dec 31, 2025	FOX RUN MANAGEMENT, L.L.C.	0.06%	25.68K	522.85K	25.68K	+100.00%
Dec 31, 2025	SKOPOS LABS, INC.	0.06%	23.75K	489.96K	2.97K	+14.30%
Dec 31, 2025	LSV ASSET MANAGEMENT	0.06%	23.1K	470K	23.1K	+100.00%
Dec 31, 2025	WINTON GROUP LTD	0.05%	21.59K	439.57K	21.59K	+100.00%
Dec 31, 2025	PENSERRA CAPITAL MANAGEMENT LLC	0.05%	18.84K	383K	18.84K	+100.00%
Dec 31, 2025	JPMORGAN CHASE & CO	0.05%	18.64K	379.47K	-153.3K	-89.16%
Dec 31, 2025	CAMPBELL & CO INVESTMENT ADVISER LLC	0.04%	17.63K	358.95K	17.63K	+100.00%
Dec 31, 2025	LEGATO CAPITAL MANAGEMENT LLC	0.04%	16.97K	345.59K	16.97K	+100.00%
Dec 31, 2025	INTEGRATED QUANTITATIVE INVESTMENTS LLC	0.04%	16.97K	345.59K	16.97K	+100.00%
Sep 30, 2025	FMR LLC	0.25%	100.53K	1.59M	-63.74K	-38.80%
Sep 30, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	13.27%	5.39M	85.26M	0	0
Sep 30, 2025	BARCLAYS PLC	0.24%	99.1K	1.57M	-22.03K	-18.19%
Sep 30, 2025	JACOBS LEVY EQUITY MANAGEMENT, INC	1.49%	607.09K	9.6M	82.75K	+15.78%
Sep 30, 2025	FRANKLIN RESOURCES INC	0.22%	87.76K	1.39M	-44.54K	-33.67%
Sep 30, 2025	SUPERSTRING CAPITAL MANAGEMENT LP	0.23%	95.08K	1.5M	95.08K	+100.00%
Sep 30, 2025	UBS GROUP AG	0.26%	103.86K	1.64M	1.09K	+1.06%
Sep 30, 2025	MONIMUS CAPITAL MANAGEMENT, LP	0.27%	108.05K	1.71M	17.66K	+19.53%
Sep 30, 2025	DEKABANK DEUTSCHE GIROZENTRALE	0.02%	7.55K	525K	0	0
Sep 30, 2025	CWM, LLC	0.02%	7.27K	115K	2.27K	+45.42%
Sep 30, 2025	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.02%	7.12K	112.62K	-1.04K	-12.73%
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.27%	110.88K	1.75M	1.53K	+1.40%
Sep 30, 2025	SG AMERICAS SECURITIES, LLC	0.02%	6.49K	103K	6.49K	+100.00%
Sep 30, 2025	BLACKROCK, INC.	6.69%	2.72M	42.99M	-15.47K	-0.57%
Sep 30, 2025	WESTERN STANDARD LLC	5.39%	2.19M	34.64M	654.99K	+42.67%
Sep 30, 2025	D. E. SHAW & CO., INC.	3.28%	1.33M	21.06M	34.04K	+2.62%
Sep 30, 2025	FEDERATED HERMES, INC.	1.27%	514.16K	8.13M	-139.87K	-21.39%
Sep 30, 2025	TWO SIGMA INVESTMENTS, LP	0.2%	82.52K	1.31M	69K	+510.29%
Sep 30, 2025	DAFNA CAPITAL MANAGEMENT LLC	0.2%	80.72K	1.28M	-49.6K	-38.06%
Sep 30, 2025	NUVEEN, LLC	0.19%	75.86K	1.2M	0	0
Sep 30, 2025	INVESCO LTD.	0.18%	74.98K	1.19M	31.58K	+72.78%
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.17%	68.66K	1.09M	22.06K	+47.33%
Sep 30, 2025	MACKENZIE FINANCIAL CORP	0.14%	56.77K	898.07K	2.89K	+5.37%
Sep 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0.23%	93.04K	1.47M	31.3K	+50.69%
Sep 30, 2025	CITADEL ADVISORS LLC	0.43%	176.14K	2.79M	153.25K	+669.26%
Sep 30, 2025	ALPS ADVISORS INC	0.05%	19.67K	311.23K	-2.28K	-10.37%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.06%	837.36K	13.25M	8.07K	+0.97%
Sep 30, 2025	REDMILE GROUP, LLC	1.36%	552.51K	8.74M	0	0
Sep 30, 2025	MORGAN STANLEY	0.97%	395.1K	6.25M	-483.64K	-55.04%
Sep 30, 2025	RANGELEY CAPITAL, LLC	0.64%	258.62K	4.09M	-26.78K	-9.38%
Sep 30, 2025	ASSENAGON ASSET MANAGEMENT S.A.	0.63%	257.52K	4.07M	156.22K	+154.22%
Sep 30, 2025	MADISON AVENUE PARTNERS, LP	6.67%	2.71M	42.84M	16.75K	+0.62%
Sep 30, 2025	TANG CAPITAL MANAGEMENT LLC	3.49%	1.42M	22.45M	0	0
Sep 30, 2025	STATE STREET CORP	3.21%	1.3M	20.61M	-81.28K	-5.87%
Sep 30, 2025	NANTAHALA CAPITAL MANAGEMENT, LLC	0.62%	250K	3.96M	0	0
Sep 30, 2025	ORBIMED ADVISORS LLC	2.51%	1.02M	16.12M	0	0
Sep 30, 2025	ALKEON CAPITAL MANAGEMENT LLC	2.09%	850.51K	13.46M	0	0
Sep 30, 2025	LOGOS GLOBAL MANAGEMENT LP	2.09%	850K	13.45M	-1.15M	-57.50%
Sep 30, 2025	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.83%	335.15K	5.3M	69.45K	+26.14%
Sep 30, 2025	PDT PARTNERS, LLC	0.82%	332.82K	5.27M	0	0
Sep 30, 2025	NORTHERN TRUST CORP	0.82%	332.76K	5.26M	59.64K	+21.83%
Sep 30, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.75%	303.12K	4.8M	264.45K	+683.73%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.72%	292.01K	4.62M	8.6K	+3.04%
Sep 30, 2025	ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	0.64%	258.75K	4.09M	194.17K	+300.67%
Sep 30, 2025	CANADA PENSION PLAN INVESTMENT BOARD	0.56%	227.3K	3.6M	-91.1K	-28.61%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.56%	226.13K	3.58M	-69.35K	-23.47%
Sep 30, 2025	AQR CAPITAL MANAGEMENT LLC	0.5%	204.35K	3.23M	133.7K	+189.24%
Sep 30, 2025	MAN GROUP PLC	0.47%	192.85K	3.05M	71.31K	+58.67%
Sep 30, 2025	METLIFE INVESTMENT MANAGEMENT, LLC	0.05%	19.75K	312.43K	0	0
Sep 30, 2025	DEUTSCHE BANK AG\	0.06%	23.26K	367.96K	-188.38K	-89.01%
Sep 30, 2025	INTECH INVESTMENT MANAGEMENT LLC	0.04%	16.67K	263.77K	-2.43K	-12.70%
Sep 30, 2025	QUEST PARTNERS LLC	0.04%	15.25K	241.24K	-10.71K	-41.26%
Sep 30, 2025	GROUP ONE TRADING, L.P.	0.04%	14.48K	229.12M	-8.55K	-37.12%
Sep 30, 2025	GSA CAPITAL PARTNERS LLP	0.06%	25.3K	400K	-36.16K	-58.83%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0.06%	25.89K	409.58K	3.95K	+17.98%
Sep 30, 2025	STRS OHIO	0.07%	28.2K	446.12K	18.8K	+200.00%
Sep 30, 2025	PANAGORA ASSET MANAGEMENT INC	0.08%	30.46K	481.89K	30.46K	+100.00%
Sep 30, 2025	CORNERSTONE INVESTMENT PARTNERS, LLC	0.03%	11.14K	176.28K	11.14K	+100.00%
Sep 30, 2025	NEW YORK STATE COMMON RETIREMENT FUND	0.03%	10.62K	167.95K	0	0
Sep 30, 2025	QUADRATURE CAPITAL LTD	0.03%	10.36K	163.93K	-36.64K	-77.95%
Sep 30, 2025	AMERICAN FINANCIAL GROUP INC	0.02%	10.11K	159.86K	0	0
Sep 30, 2025	POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY	0.02%	9.47K	149.82K	1.21K	+14.69%
Sep 30, 2025	RBF CAPITAL, LLC	0.37%	150K	2.37M	0	0
Sep 30, 2025	DIMENSIONAL FUND ADVISORS LP	0.09%	35.96K	569K	-678	-1.85%
Sep 30, 2025	LOS ANGELES CAPITAL MANAGEMENT LLC	0.09%	37K	585.39K	-4.71K	-11.28%
Sep 30, 2025	AMERICAN CENTURY COMPANIES INC	0.1%	39.17K	619.61K	39.17K	+100.00%
Sep 30, 2025	MARTINGALE ASSET MANAGEMENT L P	0.1%	39.18K	619.78M	25.32K	+182.70%
Sep 30, 2025	ERSTE ASSET MANAGEMENT GMBH	0.1%	41.4K	660.33K	20.7K	+100.00%
Sep 30, 2025	RAFFERTY ASSET MANAGEMENT, LLC	0.11%	44.07K	697.12K	-10.23K	-18.84%
Sep 30, 2025	Y-INTERCEPT (HONG KONG) LTD	0.12%	48.55K	767.98K	-56.33K	-53.71%
Sep 30, 2025	RHUMBLINE ADVISERS	0.12%	50.48K	798.55K	-1.34K	-2.58%
Sep 30, 2025	VANGUARD GROUP INC	6.69%	2.72M	43.01M	87.13K	+3.31%
Sep 30, 2025	SQUAREPOINT OPS LLC	0.25%	100.14K	1.58M	100.14K	+100.00%
Sep 30, 2025	HIGHVISTA STRATEGIES LLC	0.2%	83.05K	1.31M	30.43K	+57.84%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	3.26%	1.33M	20.97M	441.92K	+50.02%
Sep 30, 2025	ADVANTAGE ALPHA CAPITAL PARTNERS LP	0.04%	18.06K	285.69K	18.06K	+100.00%
Sep 30, 2025	AMERIPRISE FINANCIAL INC	0.3%	120.43K	1.91M	21.79K	+22.09%
Sep 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.47%	189.2K	2.99M	-569.3K	-75.06%
Sep 30, 2025	JPMORGAN CHASE & CO	0.42%	171.94K	2.72M	124.29K	+260.81%
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.38%	154.7K	2.45M	8.1K	+5.53%
Sep 30, 2025	CUBIST SYSTEMATIC STRATEGIES, LLC	0.3%	121.53K	1.92M	121.53K	+100.00%
Sep 30, 2025	JANE STREET GROUP, LLC	0.4%	162.46K	2.57M	105.17K	+183.61%
Jun 30, 2025	RANGELEY CAPITAL, LLC	0.7%	285.4K	3.81M	-122.83K	-30.09%
Jun 30, 2025	MAN GROUP PLC	0.3%	121.55K	1.62M	87.53K	+257.35%
Jun 30, 2025	BARCLAYS PLC	0.3%	121.13K	1.62M	61.27K	+102.36%
Jun 30, 2025	JANE STREET GROUP, LLC	0.28%	113.1K	1.51M	-23.3K	-17.08%
Jun 30, 2025	CANADA PENSION PLAN INVESTMENT BOARD	0.78%	318.4K	4.25M	318.4K	+100.00%
Jun 30, 2025	AMERIPRISE FINANCIAL INC	0.24%	98.64K	1.32M	98.64K	+100.00%
Jun 30, 2025	STATE OF WISCONSIN INVESTMENT BOARD	0.18%	71.92K	960.19K	71.92K	+100.00%
Jun 30, 2025	FMR LLC	0.4%	164.27K	2.19M	-277.27K	-62.80%
Jun 30, 2025	SIMPLEX TRADING, LLC	0.22%	90.74K	1.21M	20.22K	+28.68%
Jun 30, 2025	WESTERN STANDARD LLC	3.78%	1.53M	20.49M	1.4M	+1,037.68%
Jun 30, 2025	TANG CAPITAL MANAGEMENT LLC	3.49%	1.42M	18.94M	318.98K	+29.00%
Jun 30, 2025	RBF CAPITAL, LLC	0.37%	150K	2M	-20.01K	-11.77%
Jun 30, 2025	STATE STREET CORP	3.41%	1.38M	18.48M	81.72K	+6.27%
Jun 30, 2025	ALKEON CAPITAL MANAGEMENT LLC	2.09%	850.51K	11.35M	0	0
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.04%	829.3K	11.07M	23.11K	+2.87%
Jun 30, 2025	FEDERATED HERMES, INC.	1.61%	654.03K	8.73M	-570.11K	-46.57%
Jun 30, 2025	REDMILE GROUP, LLC	1.36%	552.51K	7.38M	0	0
Jun 30, 2025	JACOBS LEVY EQUITY MANAGEMENT, INC	1.29%	524.34K	7M	524.34K	+100.00%
Jun 30, 2025	JANUS HENDERSON GROUP PLC	1.16%	472.39K	6.31M	472.39K	+100.00%
Jun 30, 2025	PDT PARTNERS, LLC	0.82%	332.82K	4.44M	56.76K	+20.56%
Jun 30, 2025	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.65%	265.71K	3.55M	137.6K	+107.42%
Jun 30, 2025	NEWTYN MANAGEMENT, LLC	0.61%	246.86K	3.3M	246.86K	+100.00%
Jun 30, 2025	DEUTSCHE BANK AG\	0.52%	211.64K	2.83M	188.68K	+821.68%
Jun 30, 2025	VERITION FUND MANAGEMENT LLC	0.42%	171.76K	2.29M	130.46K	+315.88%
Jun 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.36%	146.6K	1.96M	146.6K	+100.00%
Jun 30, 2025	FRANKLIN RESOURCES INC	0.33%	132.3K	1.77M	94.01K	+245.48%
Jun 30, 2025	DAFNA CAPITAL MANAGEMENT LLC	0.32%	130.32K	1.74M	0	0
Jun 30, 2025	ASSENAGON ASSET MANAGEMENT S.A.	0.25%	101.3K	1.35M	36.36K	+55.99%
Jun 30, 2025	NEBULA RESEARCH & DEVELOPMENT LLC	0.22%	90.41K	1.21M	-25.01K	-21.67%
Jun 30, 2025	ORBIMED ADVISORS LLC	2.51%	1.02M	13.6M	0	0
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0.73%	295.48K	3.94M	139.87K	+89.88%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.7%	283.4K	3.78M	41.48K	+17.15%
Jun 30, 2025	NORTHERN TRUST CORP	0.67%	273.12K	3.65M	-16.89K	-5.82%
Jun 30, 2025	NANTAHALA CAPITAL MANAGEMENT, LLC	0.62%	250K	3.34M	0	0
Jun 30, 2025	TFG ASSET MANAGEMENT GP LTD	0.32%	128K	1.71M	-55K	-30.05%
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.28%	113.67K	1.52M	-8.18K	-6.72%
Jun 30, 2025	BANK OF NEW YORK MELLON CORP	0.27%	109.35K	1.46M	11.59K	+11.86%
Jun 30, 2025	Y-INTERCEPT (HONG KONG) LTD	0.26%	104.88K	1.4M	104.88K	+100.00%
Jun 30, 2025	UBS GROUP AG	0.25%	102.77K	1.37M	10.34K	+11.19%
Jun 30, 2025		0.19%	75.86K	1.01M	-3.87M	-98.08%
Jun 30, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	13.27%	5.39M	71.95M	3.9M	+262.56%
Jun 30, 2025	BLACKROCK, INC.	6.73%	2.73M	36.48M	-52.61K	-1.89%
Jun 30, 2025	MADISON AVENUE PARTNERS, LP	6.63%	2.69M	35.93M	2.69M	+100.00%
Jun 30, 2025	VANGUARD GROUP INC	6.48%	2.63M	35.13M	65.33K	+2.55%
Jun 30, 2025	D. E. SHAW & CO., INC.	3.19%	1.3M	17.32B	34.25K	+2.71%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	2.18%	883.56K	11.8B	142.95K	+19.30%
Jun 30, 2025	MORGAN STANLEY	2.16%	878.75K	11.73B	-818.81K	-48.23%
Jun 30, 2025	MONIMUS CAPITAL MANAGEMENT, LP	0.22%	90.4K	1.21M	6.34K	+7.54%
Jun 30, 2025	NUVEEN, LLC	0.19%	75.86K	1.01M	-3.87M	-98.08%
Jun 30, 2025	LOGOS GLOBAL MANAGEMENT LP	4.92%	2M	26.7M	0	0
Mar 31, 2025	ACADIAN ASSET MANAGEMENT LLC	0.36%	147.57K	1.5M	147.57K	+100.00%
Mar 31, 2025	NANTAHALA CAPITAL MANAGEMENT, LLC	0.62%	250K	2.55M	0	0
Mar 31, 2025	BLACKROCK, INC.	6.87%	2.79M	28.38M	55.96K	+2.05%
Mar 31, 2025	REDMILE GROUP, LLC	1.36%	552.51K	5.63M	0	0
Mar 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.3%	121.85K	1.24M	-89.46K	-42.34%
Mar 31, 2025	DRW SECURITIES, LLC	1.15%	464.9K	4.74M	464.9K	+100.00%
Mar 31, 2025	FMR LLC	1.09%	441.54K	4.5M	-5.1M	-92.03%
Mar 31, 2025		0.36%	147.1K	1.5M	17.1K	+13.15%
Mar 31, 2025	PARKMAN HEALTHCARE PARTNERS LLC	0.54%	217.75K	2.22M	-96.79K	-30.77%
Mar 31, 2025	TFG ASSET MANAGEMENT GP LTD	0.45%	183K	1.86M	80K	+77.67%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	0.38%	155.61K	1.59M	-5.86K	-3.63%
Mar 31, 2025	WALLEYE CAPITAL LLC	0.37%	150.5K	1.53M	-47.16K	-23.86%
Mar 31, 2025	JANE STREET GROUP, LLC	0.34%	136.4K	1.39M	-373.1K	-73.23%
Mar 31, 2025	WESTERN STANDARD LLC	0.33%	134.91K	1.37M	134.91K	+100.00%
Mar 31, 2025	DAFNA CAPITAL MANAGEMENT LLC	0.32%	130.32K	1.33M	0	0
Mar 31, 2025	TWO SIGMA ADVISERS, LP	0.29%	119.5K	1.22M	98.8K	+477.29%
Mar 31, 2025	MORGAN STANLEY	4.19%	1.7M	17.3M	1.04M	+158.46%
Mar 31, 2025	CLEARBRIDGE INVESTMENTS, LLC	0.39%	156.72K	1.6M	-33.34K	-17.54%
Mar 31, 2025	CUBIST SYSTEMATIC STRATEGIES, LLC	0.49%	198.41K	2.02M	197.2K	+16,297.60%
Mar 31, 2025	IKARIAN CAPITAL, LLC	0.68%	274.01K	2.79M	274.01K	+100.00%
Mar 31, 2025	NORTHERN TRUST CORP	0.72%	290.01K	2.96M	-6.46K	-2.18%
Mar 31, 2025	GOLDMAN SACHS GROUP INC	1.83%	740.61K	7.55M	205.02K	+38.28%
Mar 31, 2025	TANG CAPITAL MANAGEMENT LLC	2.71%	1.1M	11.21M	1.1M	+100.00%
Mar 31, 2025	D. E. SHAW & CO., INC.	3.11%	1.26M	12.87M	1.25M	+10,339.95%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.6%	241.92K	2.47M	-37.76K	-13.50%
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	0.58%	233.2K	2.38M	-644.96K	-73.44%
Mar 31, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	3.66%	1.49M	15.15M	1.46M	+6,294.48%
Mar 31, 2025	VANGUARD GROUP INC	6.33%	2.57M	26.15M	609.21K	+31.13%
Mar 31, 2025	CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD.	0.32%	128.1K	1.31M	98.96K	+339.52%
Mar 31, 2025	PDT PARTNERS, LLC	0.68%	276.06K	2.81M	276.06K	+100.00%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.99%	806.19K	8.22M	40.75K	+5.32%
Mar 31, 2025	ALKEON CAPITAL MANAGEMENT LLC	2.1%	850.51K	8.67M	-250.49K	-22.75%
Mar 31, 2025	ORBIMED ADVISORS LLC	2.51%	1.02M	10.38M	0	0
Mar 31, 2025	STATE STREET CORP	3.21%	1.3M	13.27M	99.16K	+8.24%
Mar 31, 2025	JPMORGAN CHASE & CO	6.41%	2.6M	26.5M	2.39M	+1,118.41%
Mar 31, 2025	FEDERATED HERMES, INC.	3.02%	1.22M	12.47M	1.1M	+882.30%
Mar 31, 2025	RBF CAPITAL, LLC	0.42%	170.01K	1.73M	170.01K	+100.00%
Mar 31, 2025	22NW, LP	0.44%	179K	1.82M	179K	+100.00%
Mar 31, 2025	CAPTION MANAGEMENT, LLC	0.97%	392.9K	4M	392.9K	+100.00%
Mar 31, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.67%	273.34K	2.79M	273.34K	+100.00%
Mar 31, 2025	CITADEL ADVISORS LLC	0.34%	138.7K	1.41M	75.2K	+118.43%
Mar 31, 2025	BLUE OWL CAPITAL HOLDINGS LP	0.66%	266.03K	2.71M	23.4K	+9.64%
Mar 31, 2024	PLATINUM INVESTMENT MANAGEMENT LTD	0.12%	34.72K	2.3M	-14.17K	-28.98%
Mar 31, 2024	HOLOCENE ADVISORS, LP	2.12%	637.98K	42.23M	637.98K	+100.00%
Mar 31, 2024	JEFFERIES FINANCIAL GROUP INC.	2.1%	633.67K	41.95M	617.77K	+3,885.35%
Mar 31, 2024	FRANKLIN RESOURCES INC	2.1%	632.05K	41.84M	-67.38K	-9.63%
Mar 31, 2024	GRANAHAN INVESTMENT MANAGEMENT, LLC	0.49%	149.01K	9.86M	149.01K	+100.00%
Mar 31, 2024	UBS GROUP AG	0.41%	124.19K	8.22M	-57.2K	-31.54%
Mar 31, 2024	CITIGROUP INC	0.39%	117.46K	7.78M	-51.94K	-30.66%
Mar 31, 2024	WCM INVESTMENT MANAGEMENT, LLC	0.39%	117.03K	7.75M	-37.63K	-24.33%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.34%	101.24K	6.7M	25.64K	+33.92%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	1.98%	595.85K	39.45M	85.64K	+16.78%
Mar 31, 2024	REDMILE GROUP, LLC	1.83%	552.51K	36.58M	552.51K	+100.00%
Mar 31, 2024	CITADEL ADVISORS LLC	1.49%	450.28K	29.81M	-309.89K	-40.77%
Mar 31, 2024	OPALEYE MANAGEMENT INC.	1.22%	367.5K	24.33M	10K	+2.80%
Mar 31, 2024	PARKMAN HEALTHCARE PARTNERS LLC	0.59%	178.34K	11.81M	-182.13K	-50.53%
Mar 31, 2024	BLUE OWL CAPITAL HOLDINGS LP	0.57%	172.63K	11.43M	-180K	-51.04%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.57%	172.48K	11.42M	-20.97K	-10.84%
Mar 31, 2024	DIMENSIONAL FUND ADVISORS LP	0.55%	165.41K	10.95M	-5.45K	-3.19%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.33%	99.63K	6.6M	5.13K	+5.43%
Mar 31, 2024	READYSTATE ASSET MANAGEMENT LP	0.31%	94.37K	6.25M	94.37K	+100.00%
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	0.3%	91.86K	6.08M	70.74K	+334.93%
Mar 31, 2024	INVESCO LTD.	0.29%	88.68K	5.87M	78.7K	+788.61%
Mar 31, 2024	ALKEON CAPITAL MANAGEMENT LLC	5.31%	1.6M	105.85M	100K	+6.67%
Mar 31, 2024	STATE STREET CORP	5.19%	1.56M	103.46M	508.53K	+48.23%
Mar 31, 2024	VANGUARD GROUP INC	5.13%	1.55M	102.33M	113.56K	+7.93%
Mar 31, 2024	DARWIN GLOBAL MANAGEMENT, LTD.	4.77%	1.44M	95.06M	375.52K	+35.41%
Mar 31, 2024	ORBIMED ADVISORS LLC	4.21%	1.27M	83.99M	0	0
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	4.04%	1.22M	80.67M	176.8K	+16.97%
Mar 31, 2024	POINT72 ASSET MANAGEMENT, L.P.	3.23%	971.88K	64.34M	890.65K	+1,096.46%
Mar 31, 2024	TCG CROSSOVER MANAGEMENT, LLC	2.92%	879.34K	58.21M	879.34K	+100.00%
Mar 31, 2024	WOODLINE PARTNERS LP	2.53%	761.7K	50.42M	177.91K	+30.47%
Mar 31, 2024	ADAR1 CAPITAL MANAGEMENT, LLC	1.12%	338.24K	22.39M	-350.07K	-50.86%
Mar 31, 2024	MILLENNIUM MANAGEMENT LLC	1.12%	337.66K	22.35M	-184.47K	-35.33%
Mar 31, 2024	NANTAHALA CAPITAL MANAGEMENT, LLC	0.98%	294K	19.46M	-16.14K	-5.21%
Mar 31, 2024	MORGAN STANLEY	0.96%	289.16K	19.14M	-636.23K	-68.75%
Mar 31, 2024	SOLEUS CAPITAL MANAGEMENT, L.P.	0.91%	273.6K	18.11M	273.6K	+100.00%
Mar 31, 2024	MARSHALL WACE, LLP	0.91%	272.97K	18.07M	223.5K	+451.77%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	0.86%	258.37K	17.1M	53.27K	+25.97%
Mar 31, 2024	AMERICAN CENTURY COMPANIES INC	0.79%	238.81K	15.81M	24.21K	+11.28%
Mar 31, 2024	NORTHERN TRUST CORP	0.78%	235.64K	15.6M	18.79K	+8.67%
Mar 31, 2024	AVIDITY PARTNERS MANAGEMENT LP	0.7%	209.7K	13.88M	209.7K	+100.00%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.69%	207.76K	13.75M	26.18K	+14.42%
Mar 31, 2024	CIBC WORLD MARKETS CORP	0.66%	200K	13.24M	200K	+100.00%
Mar 31, 2024	ADAGE CAPITAL PARTNERS GP, L.L.C.	0.63%	190K	12.58M	190K	+100.00%
Mar 31, 2024	ECOR1 CAPITAL, LLC	0.62%	187.5K	12.41M	187.5K	+100.00%
Mar 31, 2024	DEUTSCHE BANK AG\	0.41%	124.07K	8.21M	-234.2K	-65.37%
Mar 31, 2024	RAFFERTY ASSET MANAGEMENT, LLC	0.4%	119.51K	7.91M	54.23K	+83.07%
Mar 31, 2024	BRAIDWELL LP	2.45%	737.38K	48.81M	-381.58K	-34.10%
Mar 31, 2024	RUSSELL INVESTMENTS GROUP, LTD.	0.27%	82.35K	5.45M	-12.21K	-12.91%
Mar 31, 2024	ENSIGN PEAK ADVISORS, INC	0.24%	71.74K	4.75M	71.74K	+100.00%
Mar 31, 2024	JPMORGAN CHASE & CO	0.18%	55.41K	3.67M	-7.23K	-11.55%
Mar 31, 2024	SWISS NATIONAL BANK	0.17%	49.9K	3.3M	9K	+22.00%
Mar 31, 2024	CANDRIAM S.C.A.	2.16%	652K	43.16M	-167.06K	-20.40%
Mar 31, 2024	RHUMBLINE ADVISERS	0.11%	34.53K	2.29M	2.87K	+9.07%
Mar 31, 2024	CREDIT SUISSE AG/	0.11%	34.16K	2.26M	7.52K	+28.23%
Mar 31, 2024	BALYASNY ASSET MANAGEMENT L.P.	0.08%	25.51K	1.69M	7.8K	+44.01%
Mar 31, 2024	ALPS ADVISORS INC	0.08%	25.38K	1.68M	5.77K	+29.40%
Mar 31, 2024	LEGAL & GENERAL GROUP PLC	0.08%	24.58K	1.63B	5.71K	+30.23%
Mar 31, 2024	STATE OF WISCONSIN INVESTMENT BOARD	0.06%	18.93K	1.25M	-9.96K	-34.47%
Mar 31, 2024	PROFUND ADVISORS LLC	0.06%	18.66K	1.24B	7.81K	+72.04%
Mar 31, 2024	NEW YORK STATE COMMON RETIREMENT FUND	0.06%	17.12K	1.13M	6.83K	+66.35%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.04%	11.6K	767.92K	11.6K	+100.00%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.05%	14.32K	947.72K	2.88K	+25.13%
Mar 31, 2024	NEOS INVESTMENT MANAGEMENT LLC	0.05%	14.26K	944.28K	14.26K	+100.00%
Mar 31, 2024	ALGERT GLOBAL LLC	0.05%	14.2K	940K	3.56K	+33.47%
Mar 31, 2024	MIRAE ASSET GLOBAL INVESTMENTS CO., LTD.	0.04%	13.15K	661.76K	251	+1.95%
Mar 31, 2024	METLIFE INVESTMENT MANAGEMENT, LLC	0.04%	13.14K	870.07K	1.26K	+10.58%
Mar 31, 2024	AMERICAN INTERNATIONAL GROUP, INC.	0.04%	12.65K	837.63K	1.47K	+13.09%
Mar 31, 2024	AMERICAN FINANCIAL GROUP INC	0.03%	10.11K	669K	0	0
Mar 31, 2024	EDBI PTE LTD	0.03%	10.11K	668.95K	0	0
Mar 31, 2024	WELLS FARGO & COMPANY/MN	0.03%	9.31K	616.26K	3.36K	+56.56%
Mar 31, 2024	ALLIANZ ASSET MANAGEMENT GMBH	0.03%	8.9K	589.18K	8.9K	+100.00%
Mar 31, 2024	GSA CAPITAL PARTNERS LLP	0.03%	8.54K	565K	1.74K	+25.52%
Mar 31, 2024	FORA CAPITAL, LLC	0.03%	8.48K	561.38K	8.48K	+100.00%
Mar 31, 2024	FIRST TRUST ADVISORS LP	0.03%	8.25K	546.02K	8.25K	+100.00%
Mar 31, 2024	FMR LLC	16.66%	5.02M	332.23M	1.14M	+29.54%
Mar 31, 2024	BLACKROCK INC.	7.19%	2.17M	143.39M	129.22K	+6.34%
Mar 31, 2024	EVENTIDE ASSET MANAGEMENT, LLC	2.26%	680K	45.02M	100K	+17.24%
Dec 31, 2023	AMERICAN CENTURY COMPANIES INC	0.72%	214.6K	8.53M	523	+0.24%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.69%	205.1K	8.15M	105.04K	+104.98%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.65%	193.45K	7.69M	138.8K	+253.98%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.61%	181.58K	7.22M	4.63K	+2.61%
Dec 31, 2023	UBS GROUP AG	0.61%	181.39K	7.21M	174.8K	+2,653.68%
Dec 31, 2023	DIMENSIONAL FUND ADVISORS LP	0.58%	170.85K	6.79M	-425	-0.25%
Dec 31, 2023	CITIGROUP INC	0.57%	169.39K	6.73M	71.28K	+72.66%
Dec 31, 2023	WCM INVESTMENT MANAGEMENT, LLC	0.52%	154.66K	6.35M	57.12K	+58.56%
Dec 31, 2023	SCHONFELD STRATEGIC ADVISORS LLC	0.32%	95.34K	3.79M	17.54K	+22.54%
Dec 31, 2023	RUSSELL INVESTMENTS GROUP, LTD.	0.32%	94.56K	3.76M	18.68K	+24.62%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.32%	94.5K	3.76M	-49.91K	-34.56%
Dec 31, 2023	POINT72 ASSET MANAGEMENT, L.P.	0.27%	81.23K	3.23M	-68.5K	-45.75%
Dec 31, 2023	NUVEEN ASSET MANAGEMENT, LLC	0.25%	75.6K	3.01M	4.58K	+6.45%
Dec 31, 2023		0.25%	74.65K	2.97M	74.65K	+100.00%
Dec 31, 2023	DAFNA CAPITAL MANAGEMENT LLC	0.25%	74.36K	2.96M	8.4K	+12.73%
Dec 31, 2023	RAFFERTY ASSET MANAGEMENT, LLC	0.22%	65.28K	2.6M	7.09K	+12.19%
Dec 31, 2023	JPMORGAN CHASE & CO	0.21%	62.64K	2.49M	9.58K	+18.04%
Dec 31, 2023	MARSHALL WACE, LLP	0.17%	49.47K	1.97M	49.47K	+100.00%
Dec 31, 2023	PLATINUM INVESTMENT MANAGEMENT LTD	0.16%	48.88K	1.94M	48.88K	+100.00%
Dec 31, 2023	SWISS NATIONAL BANK	0.14%	40.9K	1.63M	-4.7K	-10.31%
Dec 31, 2023	NORGES BANK	0.12%	35.7K	1.42M	35.7K	+100.00%
Dec 31, 2023	QUBE RESEARCH & TECHNOLOGIES LTD	0.12%	34.54K	1.37M	25.58K	+285.60%
Dec 31, 2023	VOYA INVESTMENT MANAGEMENT LLC	0.11%	33.64K	1.34M	-38.51K	-53.38%
Dec 31, 2023	RHUMBLINE ADVISERS	0.11%	31.66K	1.26M	-886	-2.72%
Dec 31, 2023	TWO SIGMA INVESTMENTS, LP	0.11%	31.57K	1.26M	31.57K	+100.00%
Dec 31, 2023	FMR LLC	13.06%	3.87M	154.04M	269.28K	+7.47%
Dec 31, 2023	BLACKROCK INC.	6.87%	2.04M	80.98M	169.44K	+9.07%
Dec 31, 2023	ALKEON CAPITAL MANAGEMENT LLC	5.05%	1.5M	59.6M	-177.62K	-10.59%
Dec 31, 2023	VANGUARD GROUP INC	4.83%	1.43M	56.94M	25.76K	+1.83%
Dec 31, 2023	ORBIMED ADVISORS LLC	4.28%	1.27M	50.44M	-246K	-16.24%
Dec 31, 2023	BRAIDWELL LP	3.77%	1.12M	44.49M	-238.35K	-17.56%
Dec 31, 2023	DARWIN GLOBAL MANAGEMENT, LTD.	3.57%	1.06M	42.16M	1.06M	+100.00%
Dec 31, 2023	STATE STREET CORP	3.55%	1.05M	41.92M	152.37K	+16.89%
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	3.51%	1.04M	41.42M	-225.53K	-17.80%
Dec 31, 2023	MORGAN STANLEY	3.12%	925.39K	36.79M	476.69K	+106.24%
Dec 31, 2023	CANDRIAM S.C.A.	2.76%	819.06K	32.57M	78K	+10.53%
Dec 31, 2023	CITADEL ADVISORS LLC	2.56%	760.17K	30.22M	355.02K	+87.63%
Dec 31, 2023	FRANKLIN RESOURCES INC	2.36%	699.43K	27.81M	226.67K	+47.95%
Dec 31, 2023	WOODLINE PARTNERS LP	1.97%	583.79K	23.21M	-134.63K	-18.74%
Dec 31, 2023	EVENTIDE ASSET MANAGEMENT, LLC	1.96%	580K	23.06M	0	0
Dec 31, 2023	MILLENNIUM MANAGEMENT LLC	1.76%	522.13K	20.76M	318.07K	+155.87%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.72%	510.21K	20.29M	24.21K	+4.98%
Dec 31, 2023	PARKMAN HEALTHCARE PARTNERS LLC	1.22%	360.47K	14.33M	61.99K	+20.77%
Dec 31, 2023	DEUTSCHE BANK AG\	1.21%	358.28K	14.25M	345.7K	+2,749.79%
Dec 31, 2023	OPALEYE MANAGEMENT INC.	1.21%	357.5K	14.21M	-2.9K	-0.80%
Dec 31, 2023	BLUE OWL CAPITAL HOLDINGS LP	1.19%	352.63K	14.02M	352.63K	+100.00%
Dec 31, 2023	NANTAHALA CAPITAL MANAGEMENT, LLC	1.05%	310.14K	12.33M	-18.64K	-5.67%
Dec 31, 2023	BARCLAYS PLC	0.88%	259.76K	10.33M	210.25K	+424.65%
Dec 31, 2023	NORTHERN TRUST CORP	0.73%	216.85K	8.62M	3.95K	+1.85%

Insiders

Among the KROS insiders holding of 2.73% of the stake in company, SEEHRA JASBIR, CHIEF EXECUTIVE OFFICER, holds the largest shares of 385.71K. KNOWLES JULIUS, director, is the second largest KROS insider with ownership of 232.73K shares. ORBIMED ADVISORS LLC, director, stands third with possession of 119.52K shares of that stake.

Insiders	Designation	Shares Held
SEEHRA JASBIR	CHIEF EXECUTIVE OFFICER	385.71K
KNOWLES JULIUS	director	232.73K
ORBIMED ADVISORS LLC	director	119.52K
GORDON CARL L	director	119.52K
LACHEY JENNIFER	Chief Scientific Officer	95.1K
CHO ESTHER	SVP, General Counsel	39.76K
REGNANTE KEITH	CHIEF FINANCIAL OFFICER	39.26K
LERNER LORENA RAQUEL	Chief Science Officer	31.13K
ROVALDI CHRISTOPHER	Chief Operating Officer	0
ADAR1 CAPITAL MANAGEMENT, LLC	10 percent owner	0
PONTIFAX MANAGEMENT 4 G.P. (2015) LTD.	10 percent owner	0

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Feb 19, 2026	SEEHRA JASBIR	SALE	16.17	7.02K	113.43K	385.71K
Feb 18, 2026	LERNER LORENA RAQUEL	SALE	16.35	3.87K	63.32K	31.13K
Feb 18, 2026	REGNANTE KEITH	SALE	16.35	4.74K	77.48K	39.26K
Feb 18, 2026	CHO ESTHER	SALE	16.35	4.75K	77.58K	39.76K
Oct 15, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	SALE	17.75	743.36K	13.19M	0
Oct 15, 2025	PONTIFAX MANAGEMENT 4 G.P. (2015) LTD.	SALE	17.75	155.26K	2.76M	0
Apr 09, 2025	ADAR1 CAPITAL MANAGEMENT, LLC	PURCHASE	9.40	16.37K	153.75K	743.56K
Aug 13, 2024	GORDON CARL L	SALE	44.01	29.4K	1.29M	119.52K
Aug 13, 2024	ORBIMED ADVISORS LLC	SALE	44.01	29.4K	1.29M	119.52K
Jan 04, 2024	REGNANTE KEITH	SALE	45.29	40K	1.81M	0
Nov 04, 2023	REGNANTE KEITH	SALE	45.29	40K	1.81M	0
Jun 09, 2023	REGNANTE KEITH	SALE	47.25	2.58K	121.86K	0
Jun 08, 2023	REGNANTE KEITH	SALE	48.65	2.7K	131.31K	0
Jul 15, 2022	LACHEY JENNIFER	SALE	30.00	46.03K	1.38M	95.1K
Jul 13, 2022	LACHEY JENNIFER	SALE	30.00	1.92K	57.48K	95.1K
May 11, 2022	LACHEY JENNIFER	SALE	42.49	944	40.11K	86.66K
Apr 11, 2022	LACHEY JENNIFER	SALE	64.15	559	35.86K	85.7K
Apr 06, 2022	ROVALDI CHRISTOPHER	SALE	65.00	1.73K	112.32K	0
Apr 04, 2022	LACHEY JENNIFER	SALE	60.00	7.95K	477K	85.7K
Apr 01, 2022	ROVALDI CHRISTOPHER	SALE	58.83	105	6.18K	0
Mar 11, 2022	LACHEY JENNIFER	SALE	54.54	875	47.72K	85.7K
Feb 11, 2022	LACHEY JENNIFER	SALE	53.10	199	10.57K	85.7K
Jan 11, 2022	LACHEY JENNIFER	SALE	54.45	1.13K	61.75K	85.7K
Jan 05, 2022	KNOWLES JULIUS	SALE	59.00	435	25.67K	232.73K
Jan 05, 2022	LACHEY JENNIFER	SALE	60.00	2.65K	159K	85.7K
Jan 04, 2022	KNOWLES JULIUS	SALE	58.86	2.2K	129.2K	234.32K
Jan 03, 2022	KNOWLES JULIUS	SALE	59.40	162	9.62K	242.24K
Dec 15, 2021	LACHEY JENNIFER	SALE	50.00	735	36.75K	85.7K
Dec 13, 2021	LACHEY JENNIFER	SALE	53.64	7	375.48	85.7K
Dec 02, 2021	KNOWLES JULIUS	SALE	54.67	90	4.92K	251.54K
Dec 01, 2021	KNOWLES JULIUS	SALE	56.27	1.02K	57.45K	261.54K
Nov 11, 2021	LACHEY JENNIFER	SALE	59.78	4.56K	272.66K	85.7K
Nov 10, 2021	LACHEY JENNIFER	SALE	60.00	15.9K	954K	85.7K
Nov 04, 2021	LACHEY JENNIFER	SALE	50.00	10.6K	530K	85.7K
Nov 03, 2021	KNOWLES JULIUS	SALE	42.45	2.35K	99.59K	270.35K
Nov 02, 2021	KNOWLES JULIUS	SALE	43.04	991	42.65K	276.65K
Nov 01, 2021	KNOWLES JULIUS	SALE	42.43	4.8K	203.54K	279.76K
Oct 20, 2021	KNOWLES JULIUS	SALE	38.31	1.46K	56.05K	289.16K
Oct 19, 2021	KNOWLES JULIUS	SALE	38.49	460	17.71K	290.77K
Oct 18, 2021	KNOWLES JULIUS	SALE	38.46	92	3.54K	433.3K
Oct 15, 2021	KNOWLES JULIUS	SALE	40.60	92	3.74K	441.65K
Oct 14, 2021	KNOWLES JULIUS	SALE	40.13	2.65K	106.46K	446.61K
Apr 13, 2020	KNOWLES JULIUS	PURCHASE	20.98	1.19K	24.99K	1.19K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE00

SALES918.99K6

NET SHARES-918.99K6

SHARES HELD495.85K6

% NET SHARES-285.34%0%

Frequently Asked Questions