Stock Forecast Chart
Stock Price Prediction Summary
Forecast Score Based on 2 Weeks
Based on our forecast, the price of KPTI will decline by -10.60% over the next 2 Weeks and hit $6.59 by Wednesday, February 25, 2026. In that time frame, KPTI's share price is expected to range between $5.95 and $7.25.
BearishAverageBullish| Date | Predicted Lower | Predicted | Predicted Upper |
|---|---|---|---|
| Feb 26, 2026 | 7.20 | 7.82 | 8.47 |
| Feb 25, 2026 | 6.94 | 7.59 | 8.24 |
| Feb 24, 2026 | 7.10 | 7.75 | 8.41 |
| Feb 23, 2026 | 7.28 | 7.88 | 8.52 |
| Feb 20, 2026 | 7.22 | 7.85 | 8.49 |
| Feb 19, 2026 | 7.38 | 8.05 | 8.64 |
| Feb 18, 2026 | 7.13 | 7.81 | 8.39 |
| Feb 17, 2026 | 7.34 | 7.98 | 8.68 |
| Feb 16, 2026 | 7.45 | 8.11 | 8.77 |
| Feb 13, 2026 | 7.45 | 8.07 | 8.73 |
KPTI shares rose +21.30% in Thursday, February 12, 2026's trading session, rising from a previous close of $7.37 to move at $8.94. The stock demonstrated notable intraday movement (see KPTI's key stats for a full breakdown), fluctuating between $6.72 and $9.94, a +47.92% trading range. While recent weeks have seen some volatility, KPTI has managed to secure a +37.12% gain over the past 2 weeks. The upward price movement was accompanied by increased trading volume, with approximately 2.75M shares changing hands, 2.16M more than the previous session. This amounted to $24.58M in total market activity.
Will KPTI Continue Its Downward Trend?
According to analyst ratings and projections for KPTI, Karyopharm Therapeutics Inc. shares are anticipated to decrease by -5.50%, potentially reaching $8.47 per share by February 26, 2026. Short-term technical indicators currently suggest a neutral sentiment for KPTI. For deeper insights, view our sentiment analysis on AAPL covering social and institutional perspectives. However, the stock has recorded 15 positive trading days within the past 30 sessions. Based on the KPTI stock forecast, now is not the best time to buy KPTI stock because its current trading price is +14.35% above our predicted value, hinting at a possible undervaluation. For deeper insights, view our sentiment analysis on KPTI covering social and institutional perspectives.
KPTI Technical Momentum: Overbought, Oversold, or Neutral?
An analysis of Relative Strength Index (RSI) indicators provides insight into KPTI's momentum. Short-term RSIs (9, 14, and 20-day figures ranging from 66.65% to 79.42%) indicate the stock is leaning toward a strong bullish momentum phase. The 50-day RSI, at 58.75%, suggests a neutral medium-term outlook. Additionally, the 100-day RSI, at 53.85%, maintains a neutral outlook for the long term. Insights into KPTI's shareholder base show how institutional investors are positioning themselves during these momentum shifts
Karyopharm Therapeutics Short-Term Forecasts
KPTI Forecast For Next 5 Days
Our algorithm anticipates Karyopharm Therapeutics (KPTI) stock could hit $6.17 by Feb 19, 2026. This represents a -30.97% fall from today's price, following a -27.39% change over the past five days.
KPTI Forecast For Next 30 Days
Based on analysis of market trends, the outlook for Karyopharm Therapeutics Inc. (KPTI) stock over the next 30 days is largely negative. Price forecasts suggest an average target of $6.91, which would mean a -22.71% decrease from the current price of $8.94. Projections for this period range from a high of $8.83 to a low of $5.42.
KPTI Forecast For Next 90 Days
Our proprietary market analysis suggests predictions for Karyopharm Therapeutics's price over the next three months point to a rise. KPTI stock is expected to peak at $17.54 on Mar 20, 2026 after potentially dipping to $9.97 on Feb 13, 2026. On average, KPTI is likely to trade around $14.18 in the coming 90 days.
Karyopharm Therapeutics Stock Forecast 2025
Based on our predictive models, Karyopharm Therapeutics (KPTI) is expected to trade between $8.86 and $29.76 throughout 2026. This would result in an average price of $17.90, potentially offering investors a +100.22% return from current levels.
Karyopharm Therapeutics Inc. Monthly Forecast 2026–2027
February 2026
According to our latest forecast models, Karyopharm Therapeutics Inc. (KPTI) is positioned to show a strong performance in February 2026. The price is predicted to move between $9.97 and $12.99, settling at an average of $11.11. This could translate to a +24.27% gain.
March 2026
Based on current market signals, Karyopharm Therapeutics Inc. is projected to trend march 2026. We forecast a trading range from $12.66 to $17.54, with a likely average price of $15.24. Investors could expect a potential return of +70.47%.
April 2026
Our predictive algorithms indicate Karyopharm Therapeutics Inc. stock may see a shift in April 2026. The expected range spans $12.20–$17.04, with an average target of $15.21. This represents a positive outlook and a possible gain of +70.13%.
May 2026
Analyzing established trends, Karyopharm Therapeutics Inc. looks set to move in May 2026. Projections place the stock between $11.19 and $17.24, averaging around $13.59. This suggests a +52.01% gain from current levels.
June 2026
Market indicators suggest Karyopharm Therapeutics Inc. could experience notable changes during June 2026. Prices could fluctuate within $12.98 to $18.03, with a midpoint forecast of $16.54. The stock might deliver a +85.01% gain.
July 2026
Forecasting for July 2026, models estimate that Karyopharm Therapeutics Inc. may undergo key fluctuations. If trends hold, the stock might trade between $11.07 and $22.21, averaging $16.14. This signals a positive trajectory with potential returns around +80.54%.
August 2026
According to our latest forecast models, Karyopharm Therapeutics Inc. (KPTI) is positioned to show a strong performance in August 2026. The price is predicted to move between $13.70 and $26.02, settling at an average of $22.68. This could translate to a +153.69% gain.
September 2026
Based on current market signals, Karyopharm Therapeutics Inc. is projected to trend september 2026. We forecast a trading range from $10.61 to $19.30, with a likely average price of $17.42. Investors could expect a potential return of +94.85%.
October 2026
Our predictive algorithms indicate Karyopharm Therapeutics Inc. stock may see a shift in October 2026. The expected range spans $12.08–$24.96, with an average target of $21.66. This represents a positive outlook and a possible gain of +142.28%.
November 2026
Analyzing established trends, Karyopharm Therapeutics Inc. looks set to move in November 2026. Projections place the stock between $10.72 and $27.89, averaging around $22.50. This suggests a +151.68% gain from current levels.
December 2026
Market indicators suggest Karyopharm Therapeutics Inc. could experience notable changes during December 2026. Prices could fluctuate within $8.86 to $29.76, with a midpoint forecast of $21.56. The stock might deliver a +141.16% gain.
January 2027
Forecasting for January 2027, models estimate that Karyopharm Therapeutics Inc. may undergo key fluctuations. If trends hold, the stock might trade between $9.58 and $34.16, averaging $27.21. This signals a positive trajectory with potential returns around +204.36%.
February 2027
According to our latest forecast models, Karyopharm Therapeutics Inc. (KPTI) is positioned to show a strong performance in February 2027. The price is predicted to move between $9.00 and $30.84, settling at an average of $25.29. This could translate to a +182.89% gain.
KPTI's history of dividends and stock splits also plays a role in long-term investor confidence.

