How many institutions own CABA stock?

A company's 13F filings with the Securities and Exchange Commission (SEC) provides investors with comprehensive information about institutional ownership in a listed company, a sign of strength in terms of how many institutions have confidence in that company. The number of institutional investors who currently own CABA shares is 116, representing 79.8% of the company's common stock.

Who are the major shareholders selling Cabaletta Bio, Inc. stock?

SUSQUEHANNA INTERNATIONAL GROUP, LLP, in the last quarter, reduced its stake in CABA by -62.84% restricting it's holding to 138.28 thousand shares of worth nearly $302.84K. BNP PARIBAS ARBITRAGE, SNC also lessened -10.43% of the CABA shares from its portfolio, reducing its holding to 1.64 thousand shares of worth $3.59K. WELLS FARGO & COMPANY/MN also shunned CABA shares holding by -33.33% last quarter which brought its holding to 2 thousand shares worth $4.38K.

Investors who are buying CABA stock?

As per its latest 13F filing, BARCLAYS PLC increased its stake in CABA by 7,058.48% in the last quarter. The institutional holder raised its holding to 220.7 thousand shares having worth more than $483.32K. NORTHERN TRUST CORP also added 5.05% more shares of CABA to its portfolio, raising its holding to 238.44 thousand shares of worth $522.19K. BOOTHBAY FUND MANAGEMENT, LLC also increased its CABA shares holding by 100% which brought its holding to 243.45 thousand shares worth $533.15K.

CABA's major insiders: who are they?

The insider with the most stakes in CABA is Nichtberger Steven , President & CEO at the company. Additionally, CABA stock is highly held by 10 percent owner Flynn James E and 10 percent owner 5AM Ventures V, L.P. among others.

Did an insider recently sell CABA stock?

Company executives, directors, and other insiders own 1.65% percent of Cabaletta Bio, Inc.'s stock. Within the last six months, there have been 0 transaction(s) in which CABA insiders have sold stock, totaling 0 shares. Insiders that have sold shares include BINDER GWENDOLYN and 5AM VENTURES V, L.P..

Which insider recently purchased CABA stock?

There have been 8 transaction(s) during the past 6-months in which Cabaletta Bio, Inc. insiders have bought stock, totalling 132073 shares

How much of CABA does insiders own?

Around 1.28M Cabaletta Bio, Inc. shares are held by insiders, which represents about 1.65% of CABA stock.

Who is the insider with the largest stake?

CABA President & CEO, Nichtberger Steven holds the largest portfolio of the company's shares. CABA shares owned by Nichtberger total nearly 1.03 million.

Which institution holds the most shares in CABA?

BARCLAYS PLC is the largest institutional owner in CABA which holds 220.7 thousand shares worth $483.32K or 0.22% of the total CABA shares outstanding followed by NORTHERN TRUST CORP with ownership of 238.44 thousand shares representing 0.23% of the CABA ownership. SUSQUEHANNA INTERNATIONAL GROUP, LLP is the third largest stakeholder with 138.28 thousand shares or 0.14% of the ownership worth more than $302.84K.

Is Cabaletta Bio, Inc. stock optionable?

Stock options give the owner the ability but not the obligation to buy or sell a security at a predetermined price and date. Stock options can be classified into two types: puts and calls. A put is a bet on falling stock, and a call is a bet on rising stock. As far as the CABA is concerned, it is a stock which is optionable.

Is there a short position on CABA's shares?

Number of CABA shares short is 5.82M. Shares short is a market sentiment in which investors have sold their shares short in a given stock but have not yet covered them or closed them out.

About how many outstanding CABA shares are there?

As of today, 91.47M shares of CABA are outstanding.

Is there many float in CABA stock?

Float represents the number of tradeable shares in a specific stock. By subtracting restricted and closely-held shares from a firm's total outstanding shares, we can calculate its floating stock. The term "closely-held shares" refers to shares held by employees, major shareholders, and company insiders. At present, CABA has 61.64M shares in float.

CABA short ratio: what is it?

Short ratio is calculated by dividing the number of short shares, short interest or bets that shareholders will sell short from the average daily volume. A higher ratio indicates longer times needed to repurchase borrowed shares (sold). The short ratio for CABA is 4.6.

Cabaletta Bio (CABA) insider trading activity: Get Latest News Today

Stock Outstanding Shares

Making an investment decision in the stock market involves a certain amount of risk, so it's important to thoroughly review a company's stock before making any decisions. Stock float, number of short positions and outstanding shares are among the many factors an investor should take into account.

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares6.37

Short Percent Of Float6.48

Shares Outstanding91.47M

Shares Float61.64M

Shares Short5.82M

Short Ratio4.6

6.48%

Short % of Float

6.37%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

1.65% Percentage of Shares held by All Insiders

79.8% Percentage of Shares held by All Institutions

81.14% Percentage of Float held by Institutions

116

Number of Institutions Holding Shares

Institutional Ownership

About 79.8% of CABA shares are held by financial institutions. BARCLAYS PLC is the top corporate investor, holding 220.7K shares valued at $483.32K. A 0.22% stake in Cabaletta Bio, Inc. is owned by the company. NORTHERN TRUST CORP owns 238.44K shares valued at $522.19K, which translates its holding of 0.23% of the stake in the company.

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Dec 31, 2025	BARCLAYS PLC	0.22%	220.7K	483.32K	217.61K	+7,058.48%
Dec 31, 2025	NORTHERN TRUST CORP	0.23%	238.44K	522.19K	11.46K	+5.05%
Dec 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.14%	138.28K	302.84K	-233.83K	-62.84%
Dec 31, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.24%	243.45K	533.15K	243.45K	+100.00%
Dec 31, 2025	NISA INVESTMENT ADVISORS, LLC	0%	811	1.78K	0	0
Dec 31, 2025	FLAGSHIP HARBOR ADVISORS, LLC	0%	1K	2.19K	1K	+100.00%
Dec 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0%	1.64K	3.59K	-191	-10.43%
Dec 31, 2025	GF FUND MANAGEMENT CO. LTD.	0%	1.89K	4.14K	1.89K	+100.00%
Dec 31, 2025	WELLS FARGO & COMPANY/MN	0%	2K	4.38K	-1K	-33.33%
Dec 31, 2025	PNC FINANCIAL SERVICES GROUP, INC.	0%	4.6K	10.07K	4K	+666.67%
Dec 31, 2025	MIRAE ASSET GLOBAL INVESTMENTS CO., LTD.	0%	4.68K	10.25K	4.68K	+100.00%
Dec 31, 2025	JPMORGAN CHASE & CO	0.01%	9.81K	21.47K	-527.84K	-98.18%
Dec 31, 2025	HB WEALTH MANAGEMENT, LLC	0.01%	10K	21.9K	10K	+100.00%
Dec 31, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.01%	13.01K	28.04K	-73	-0.56%
Dec 31, 2025	CRA FINANCIAL SERVICES, LLC	0.01%	15K	32.85K	0	0
Dec 31, 2025	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.02%	15.69K	34.35K	15.69K	+100.00%
Dec 31, 2025	ANTIPODES PARTNERS LTD	0.02%	17.19K	37.64K	17.19K	+100.00%
Dec 31, 2025	CLEAR HARBOR ASSET MANAGEMENT, LLC	0.02%	19.5K	42.71K	19.5K	+100.00%
Dec 31, 2025	LPL FINANCIAL LLC	0.04%	42.62K	93.33K	42.62K	+100.00%
Dec 31, 2025	BANK OF NEW YORK MELLON CORP	0.05%	54.05K	118.36K	6.24K	+13.05%
Dec 31, 2025	MATAURO, LLC	0.05%	55.11K	120.69K	55.11K	+100.00%
Dec 31, 2025	AMERICAN CENTURY COMPANIES INC	0.06%	58.78K	128.72K	46.75K	+388.51%
Dec 31, 2025	DYNAMIC TECHNOLOGY LAB PRIVATE LTD	0.07%	66.79K	146K	66.79K	+100.00%
Dec 31, 2025	CITIGROUP INC	0.07%	73.77K	161.57K	73.42K	+20,858.52%
Dec 31, 2025	TD ASSET MANAGEMENT INC	0.09%	88.6K	194.03K	0	0
Dec 31, 2025	LETKO, BROSSEAU & ASSOCIATES INC	0.09%	90.48K	198.14K	90.48K	+100.00%
Dec 31, 2025	GOLDMAN SACHS GROUP INC	0.24%	246.5K	539.84K	246.5K	+100.00%
Dec 31, 2025	RAIFFEISEN BANK INTERNATIONAL AG	0.44%	450K	967.5K	100K	+28.57%
Dec 31, 2025	BLACKROCK, INC.	2.28%	2.33M	5.1M	707.6K	+43.66%
Dec 31, 2025	VANGUARD GROUP INC	4.32%	4.42M	9.68M	228.7K	+5.46%
Dec 31, 2025	JENNISON ASSOCIATES LLC	8.71%	8.91M	19.5M	408.16K	+4.80%
Dec 31, 2025	ALMITAS CAPITAL LLC	0.38%	387.49K	848.61K	0	0
Dec 31, 2025	683 CAPITAL MANAGEMENT, LLC	0.38%	388.56K	850.95K	388.56K	+100.00%
Dec 31, 2025	STATE STREET CORP	0.42%	425.48K	931.8K	48.68K	+12.92%
Dec 31, 2025		0.49%	505.43K	1.11M	505.43K	+100.00%
Dec 31, 2025	BURKEHILL GLOBAL MANAGEMENT, LP	0.68%	700K	1.53M	0	0
Dec 31, 2025	TWO SIGMA ADVISERS, LP	0.72%	737.9K	1.62M	406.9K	+122.93%
Dec 31, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	8.63%	8.83M	19.34M	0	0
Dec 31, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	9.46%	9.68M	21.19M	0	0
Dec 31, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	9.64%	9.86M	21.59M	1.5M	+17.89%
Dec 31, 2025	RENAISSANCE TECHNOLOGIES LLC	1.49%	1.52M	3.33M	183.16K	+13.67%
Dec 31, 2025	TWO SIGMA INVESTMENTS, LP	1.8%	1.84M	4.03M	1.37M	+291.05%
Dec 31, 2025	MILLENNIUM MANAGEMENT LLC	2.68%	2.74M	5.99M	2.05M	+298.49%
Dec 31, 2025	XTX TOPCO LTD	0.15%	155.39K	340.3K	-128.91K	-45.34%
Dec 31, 2025	STONEPINE CAPITAL MANAGEMENT, LLC	0.17%	171.1K	374.71K	171.1K	+100.00%
Dec 31, 2025	HUDSON BAY CAPITAL MANAGEMENT LP	0.14%	138.73K	303.82K	138.73K	+100.00%
Dec 31, 2025	SQUAREPOINT OPS LLC	0.15%	149.09K	326.52K	137.23K	+1,156.27%
Dec 31, 2025	JANE STREET GROUP, LLC	0.18%	179.1K	392.23K	-11.1K	-5.84%
Dec 31, 2025	CITADEL ADVISORS LLC	0.22%	222.6K	487.49K	-22.2K	-9.07%
Dec 31, 2025	OMERS ADMINISTRATION CORP	0.09%	95.4K	208.93K	95.4K	+100.00%
Dec 31, 2025	SCHRODER INVESTMENT MANAGEMENT GROUP	0.74%	756.64K	1.63M	756.64K	+100.00%
Dec 31, 2025	IKARIAN CAPITAL, LLC	0.88%	900K	1.97M	900K	+100.00%
Dec 31, 2025	OPALEYE MANAGEMENT INC.	0.88%	900K	1.97M	91.12K	+11.26%
Dec 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.07%	1.09M	2.4M	-200.99K	-15.52%
Dec 31, 2025	JONES FINANCIAL COMPANIES LLLP	0.02%	20.66K	45.25K	653	+3.26%
Dec 31, 2025	VANGUARD PERSONALIZED INDEXING MANAGEMENT, LLC	0.02%	22.38K	49.02K	233	+1.05%
Dec 31, 2025	CALLAN FAMILY OFFICE, LLC	0.02%	22.58K	49.44K	22.58K	+100.00%
Dec 31, 2025	MERCER GLOBAL ADVISORS INC /ADV	0.03%	26.51K	58.06K	26.51K	+100.00%
Dec 31, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0.03%	30.35K	66.46M	25.98K	+594.87%
Dec 31, 2025	SG AMERICAS SECURITIES, LLC	0.03%	30.63K	67K	9.37K	+44.04%
Dec 31, 2025	LIGHTHOUSE INVESTMENT PARTNERS, LLC	0.04%	38.88K	85.15K	38.88K	+100.00%
Dec 31, 2025	JEFFERIES FINANCIAL GROUP INC.	0.04%	45.13K	98.82K	-2.38K	-5.00%
Dec 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.05%	50.82K	111.31K	0	0
Dec 31, 2025	GSA CAPITAL PARTNERS LLP	0.3%	303.99K	666K	303.99K	+100.00%
Dec 31, 2025	UBS GROUP AG	0.41%	415.68K	910.33K	10.56K	+2.61%
Dec 31, 2025	DIMENSIONAL FUND ADVISORS LP	0.44%	452.04K	989.97K	452.04K	+100.00%
Dec 31, 2025	ENSIGN PEAK ADVISORS, INC	0.54%	550K	1.2M	550K	+100.00%
Dec 31, 2025	PRIVATE ADVISOR GROUP, LLC	0.01%	14.73K	32.25K	14.73K	+100.00%
Dec 31, 2025	MARSHALL WACE, LLP	0.94%	959.08K	2.1M	-366.97K	-27.67%
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.06%	1.09M	2.38M	165.48K	+17.98%
Dec 31, 2025	MORGAN STANLEY	1.31%	1.34M	2.94M	-130.97K	-8.88%
Dec 31, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.13%	130.68K	286.18K	35K	+36.58%
Dec 31, 2025	GRAHAM CAPITAL MANAGEMENT, L.P.	0.15%	151.45K	331.68K	151.45K	+100.00%
Dec 31, 2025	SCHONFELD STRATEGIC ADVISORS LLC	1.18%	1.2M	2.64M	159.9K	+15.31%
Dec 31, 2025	WOODLINE PARTNERS LP	1.22%	1.25M	2.74M	-885.11K	-41.45%
Dec 31, 2025	SUPERSTRING CAPITAL MANAGEMENT LP	2.2%	2.25M	4.94M	709.03K	+45.91%
Dec 31, 2025	CORMORANT ASSET MANAGEMENT, LP	4.3%	4.4M	9.64M	-600K	-12.00%
Dec 31, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.32%	331.23K	725.38K	242.07K	+271.51%
Dec 31, 2025	INVESCO LTD.	0.19%	189.2K	414.34K	66.4K	+54.07%
Sep 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.27%	1.29M	3.03M	-892.09K	-40.79%
Sep 30, 2025	FRED ALGER MANAGEMENT, LLC	0.06%	59.81K	139.96K	0	0
Sep 30, 2025	NORTHERN TRUST CORP	0.22%	226.99K	531.15K	93.97K	+70.64%
Sep 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.36%	372.11K	870.73K	248.48K	+201.00%
Sep 30, 2025	TD ASSET MANAGEMENT INC	0.09%	88.6K	207.32K	0	0
Sep 30, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.09%	89.16K	208.63K	89.16K	+100.00%
Sep 30, 2025	JEFFERIES FINANCIAL GROUP INC.	0.05%	47.5K	111.15K	-1.95M	-97.62%
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.05%	47.81K	111.88K	0	0
Sep 30, 2025	ROYAL BANK OF CANADA	0.09%	91.72K	214K	91.72K	+100.00%
Sep 30, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.09%	95.68K	223.88K	50K	+109.47%
Sep 30, 2025	JANE STREET GROUP, LLC	0.1%	104.66K	244.91K	-133.66K	-56.08%
Sep 30, 2025	FEDERATED HERMES, INC.	0.11%	112.03K	262.15K	-232.51K	-67.48%
Sep 30, 2025	JPMORGAN CHASE & CO	0.87%	537.65K	1.26M	456.85K	+565.44%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.9%	920.34K	2.15M	366.88K	+66.29%
Sep 30, 2025	ALYESKA INVESTMENT GROUP, L.P.	1.27%	1.3M	3.04M	-3.5M	-72.92%
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	1.31%	1.34M	3.13M	1.21M	+962.19%
Sep 30, 2025	BLACKROCK, INC.	1.59%	1.62M	3.79M	650.27K	+67.00%
Sep 30, 2025	STATE STREET CORP	0.37%	376.8K	881.71K	158.83K	+72.87%
Sep 30, 2025	UBS GROUP AG	0.4%	405.12K	947.98K	-66.92K	-14.18%
Sep 30, 2025	MARSHALL WACE, LLP	1.3%	1.33M	3.1M	1.14M	+594.42%
Sep 30, 2025	MORGAN STANLEY	1.44%	1.47M	3.45M	149.87K	+11.31%
Sep 30, 2025	SUPERSTRING CAPITAL MANAGEMENT LP	1.51%	1.54M	3.61M	483.76K	+45.60%
Sep 30, 2025	HEIGHTS CAPITAL MANAGEMENT, INC	2.04%	2.08M	4.88M	-1.06M	-33.71%
Sep 30, 2025	WOODLINE PARTNERS LP	2.09%	2.14M	5M	916.88K	+75.25%
Sep 30, 2025	CORMORANT ASSET MANAGEMENT, LP	4.89%	5M	11.7M	0	0
Sep 30, 2025	CRA FINANCIAL SERVICES, LLC	0.02%	15K	35.1K	4K	+36.36%
Sep 30, 2025	JONES FINANCIAL COMPANIES LLLP	0.03%	20.01K	47.22K	20.01K	+100.00%
Sep 30, 2025	SG AMERICAS SECURITIES, LLC	0.03%	21.26K	50K	-2.78K	-11.58%
Sep 30, 2025	VANGUARD PERSONALIZED INDEXING MANAGEMENT, LLC	0.04%	22.15K	51.83K	-2.8K	-11.21%
Sep 30, 2025	SUSQUEHANNA PORTFOLIO STRATEGIES, LLC	0.05%	33.94K	79.41K	33.94K	+100.00%
Sep 30, 2025	CUBIST SYSTEMATIC STRATEGIES, LLC	0.06%	37.74K	88.32K	-197.53K	-83.96%
Sep 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	8.63%	8.83M	20.66M	0	0
Sep 30, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	9.46%	9.68M	22.64M	0	0
Sep 30, 2025	CAPTION MANAGEMENT, LLC	0.24%	250K	585K	250K	+100.00%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.43%	268.06K	627.26K	-230.19K	-46.20%
Sep 30, 2025	ALMITAS CAPITAL LLC	0.38%	387.49K	906.73K	20K	+5.44%
Sep 30, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	8.18%	8.36M	19.57M	1.57M	+23.09%
Sep 30, 2025	INVESCO LTD.	0.12%	122.8K	287.35K	37.97K	+44.76%
Sep 30, 2025	TWO SIGMA INVESTMENTS, LP	0.46%	470.48K	1.1M	218.12K	+86.43%
Sep 30, 2025	MILLENNIUM MANAGEMENT LLC	0.67%	686.81K	1.61M	-168.52K	-19.70%
Sep 30, 2025	VANGUARD GROUP INC	4.1%	4.19M	9.81M	740.03K	+21.45%
Sep 30, 2025	CITADEL ADVISORS LLC	0.24%	244.8K	572.83K	168.3K	+220.00%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	0.27%	272.6K	637.87K	-80.71K	-22.84%
Sep 30, 2025	TWO SIGMA ADVISERS, LP	0.32%	331K	774.54K	-82.6K	-19.97%
Sep 30, 2025	TRUE WEALTH DESIGN, LLC	0%	0	-	-17	-100.00%
Sep 30, 2025	MID-AMERICAN WEALTH ADVISORY GROUP, INC.	0%	0	-	-91	-100.00%
Sep 30, 2025	CATALYST FUNDS MANAGEMENT PTY LTD	0%	0	-	-21K	-100.00%
Sep 30, 2025	BLUE OWL CAPITAL HOLDINGS LP	0%	0	-	-1.13M	-100.00%
Sep 30, 2025	EVERSOURCE WEALTH ADVISORS, LLC	0%	0	-	-41	-100.00%
Sep 30, 2025	MYDA ADVISORS LLC	0%	0	-	-40K	-100.00%
Sep 30, 2025	CWM, LLC	0%	0	-	-1.6K	-100.00%
Sep 30, 2025	CLEAR STREET MARKETS LLC	0%	0	-	-4.82K	-100.00%
Sep 30, 2025	SAVANT CAPITAL, LLC	0%	0	-	-12.47K	-100.00%
Sep 30, 2025	HUDSON BAY CAPITAL MANAGEMENT LP	0%	0	-	-13.07K	-100.00%
Sep 30, 2025	PRUDENTIAL FINANCIAL INC	0%	0	-	-284K	-100.00%
Sep 30, 2025	XTX TOPCO LTD	0.28%	284.3K	665.26K	187.04K	+192.31%
Sep 30, 2025	ACADIAN ASSET MANAGEMENT LLC	0.18%	186.52K	433K	171.38K	+1,131.89%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.05%	50.82K	118.93K	203	+0.40%
Sep 30, 2025	QUADRATURE CAPITAL LTD	0.04%	42.91K	100.41K	42.91K	+100.00%
Sep 30, 2025	THRIVENT FINANCIAL FOR LUTHERANS	0%	0	-	-95.33K	-100.00%
Sep 30, 2025	OPTIVER HOLDING B.V.	0%	24	56	24	+100.00%
Sep 30, 2025	CITIGROUP INC	0%	352	824	-62.15K	-99.44%
Sep 30, 2025	BRYN MAWR TRUST CO	0%	450	1.05K	450	+100.00%
Sep 30, 2025	SBI SECURITIES CO., LTD.	0%	456	1.07K	-6.06K	-93.00%
Sep 30, 2025	PNC FINANCIAL SERVICES GROUP, INC.	0%	600	1.4K	-709	-54.16%
Sep 30, 2025	NISA INVESTMENT ADVISORS, LLC	0%	811	1.9K	-101	-11.07%
Sep 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0%	939	2.2K	0	0
Sep 30, 2025	RISE ADVISORS, LLC	0%	1.08K	2.53K	0	0
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0%	1.83K	4.29K	-47.24K	-96.27%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0%	3K	7.02K	-3.69K	-55.13%
Sep 30, 2025	AMERICAN CENTURY COMPANIES INC	0.02%	12.03K	28.16K	12.03K	+100.00%
Sep 30, 2025	FMR LLC	0.02%	14.06K	32.91K	-1.39K	-9.01%
Sep 30, 2025	JENNISON ASSOCIATES LLC	8.31%	8.5M	19.88M	2.48M	+41.15%
Sep 30, 2025	SCHONFELD STRATEGIC ADVISORS LLC	1.02%	1.04M	2.44M	-440.67K	-29.68%
Sep 30, 2025	BARCLAYS PLC	0.01%	3.08K	7.22K	-6.65K	-68.34%
Sep 30, 2025	RAIFFEISEN BANK INTERNATIONAL AG	0.34%	350K	833K	50K	+16.67%
Sep 30, 2025	BURKEHILL GLOBAL MANAGEMENT, LP	0.68%	700K	1.64M	-1.2M	-63.16%
Sep 30, 2025	OPALEYE MANAGEMENT INC.	0.79%	808.88K	1.89M	808.88K	+100.00%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.89%	553.46K	841.55K	-587.84K	-51.51%
Jun 30, 2025	HEIGHTS CAPITAL MANAGEMENT, INC	5.08%	3.14M	4.78M	3.14M	+100.00%
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	3.53%	2.19M	3.33M	1.7M	+346.95%
Jun 30, 2025	PRUDENTIAL FINANCIAL INC	0.46%	284K	431.68K	-3.49K	-1.21%
Jun 30, 2025	AXA S.A.	0.44%	270.52K	411.18K	439	+0.16%
Jun 30, 2025	JPMORGAN CHASE & CO	0.13%	80.8K	122.81K	-170.64K	-67.87%
Jun 30, 2025	JEFFERIES FINANCIAL GROUP INC.	3.23%	2M	3.04M	2M	+100.00%
Jun 30, 2025	ANSON FUNDS MANAGEMENT LP	2.95%	1.82M	2.77M	1.82M	+100.00%
Jun 30, 2025	SCHONFELD STRATEGIC ADVISORS LLC	2.4%	1.48M	2.26M	-177.57K	-10.68%
Jun 30, 2025	MORGAN STANLEY	2.14%	1.32M	2.01M	-384.08K	-22.48%
Jun 30, 2025	WOODLINE PARTNERS LP	1.97%	1.22M	1.85M	1.22M	+100.00%
Jun 30, 2025	STATE STREET CORP	0.35%	217.97K	331.31K	-720.75K	-76.78%
Jun 30, 2025	MARSHALL WACE, LLP	0.31%	190.96K	290.26K	157.5K	+470.70%
Jun 30, 2025	NORTHERN TRUST CORP	0.22%	133.02K	202.19K	-266.75K	-66.73%
Jun 30, 2025	CITADEL ADVISORS LLC	0.12%	76.5K	116.28K	36K	+88.89%
Jun 30, 2025	VANGUARD GROUP INC	5.58%	3.45M	5.25M	606.49K	+21.32%
Jun 30, 2025	BLUE OWL CAPITAL HOLDINGS LP	1.82%	1.13M	1.71M	1.13M	+100.00%
Jun 30, 2025	SUPERSTRING CAPITAL MANAGEMENT LP	1.71%	1.06M	1.61M	601.79K	+131.12%
Jun 30, 2025	BLACKROCK, INC.	1.57%	970.6K	1.48M	-2.48M	-71.88%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.08%	50.62K	76.94K	-109.25K	-68.34%
Jun 30, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	15.64%	9.68M	14.71M	6.92M	+250.51%
Jun 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	14.27%	8.83M	13.42M	5.2M	+142.94%
Jun 30, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	10.98%	6.79M	10.33M	2.82M	+71.13%
Jun 30, 2025	JENNISON ASSOCIATES LLC	9.73%	6.02M	9.15M	3.59M	+147.36%
Jun 30, 2025	SEI INVESTMENTS CO	0%	0	-	-12.18K	-100.00%
Jun 30, 2025	MILLENNIUM MANAGEMENT LLC	1.38%	855.33K	1.3M	686.43K	+406.42%
Jun 30, 2025	CUBIST SYSTEMATIC STRATEGIES, LLC	0.38%	235.27K	357.61K	235.27K	+100.00%
Jun 30, 2025		0.48%	300K	531K	0	0
Jun 30, 2025	ALMITAS CAPITAL LLC	0.59%	367.49K	558.59K	0	0
Jun 30, 2025	TCG CROSSOVER MANAGEMENT, LLC	0.14%	86.8K	131.93K	0	0
Jun 30, 2025	FRED ALGER MANAGEMENT, LLC	0.1%	59.81K	90.92K	-417.4K	-87.47%
Jun 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.08%	49.07K	74.58M	-12.34K	-20.09%
Jun 30, 2025	MYDA ADVISORS LLC	0.06%	40K	60.8K	40K	+100.00%
Jun 30, 2025	POINT72 ASIA (SINGAPORE) PTE. LTD.	0.06%	34.77K	52.85K	34.77K	+100.00%
Jun 30, 2025	AQR CAPITAL MANAGEMENT LLC	0.05%	32.13K	48.84M	-41.83K	-56.56%
Jun 30, 2025	VANGUARD PERSONALIZED INDEXING MANAGEMENT, LLC	0.04%	24.95K	37.92K	5.57K	+28.74%
Jun 30, 2025	TWO SIGMA SECURITIES, LLC	0.03%	16.49K	25.07K	16.49K	+100.00%
Jun 30, 2025	FMR LLC	0.03%	15.46K	23.49M	11.3K	+271.45%
Jun 30, 2025	ACADIAN ASSET MANAGEMENT LLC	0.02%	15.14K	23K	-667.53K	-97.78%
Jun 30, 2025	HUDSON BAY CAPITAL MANAGEMENT LP	0.02%	13.07K	19.87K	13.07K	+100.00%
Jun 30, 2025	DRW SECURITIES, LLC	0.02%	12.84K	19.52K	12.84K	+100.00%
Jun 30, 2025	SAVANT CAPITAL, LLC	0.02%	12.47K	18.96K	12.47K	+100.00%
Jun 30, 2025	CRA FINANCIAL SERVICES, LLC	0.02%	11K	16.72K	0	0
Jun 30, 2025	CLEAR STREET MARKETS LLC	0.01%	4.82K	7.33K	4.82K	+100.00%
Jun 30, 2025	POINT72 (DIFC) LTD	0%	2.43K	3.7K	2.43K	+100.00%
Jun 30, 2025	TRUVESTMENTS CAPITAL LLC	0%	1.97K	3K	0	0
Jun 30, 2025	RISE ADVISORS, LLC	0%	1.08K	1.65K	1.08K	+100.00%
Jun 30, 2025	FEDERATION DES CAISSES DESJARDINS DU QUEBEC	0%	340	517	0	0
Jun 30, 2025	MID-AMERICAN WEALTH ADVISORY GROUP, INC.	0%	91	138	91	+100.00%
Jun 30, 2025	EVERSOURCE WEALTH ADVISORS, LLC	0%	41	62	-49	-54.44%
Jun 30, 2025	TRUE WEALTH DESIGN, LLC	0%	17	26	-46	-73.02%
Jun 30, 2025	ROTHSCHILD INVESTMENT LLC	0%	0	-	-70	-100.00%
Jun 30, 2025	CORMORANT ASSET MANAGEMENT, LP	8.08%	5M	7.6M	5M	+100.00%
Jun 30, 2025	ALYESKA INVESTMENT GROUP, L.P.	7.76%	4.8M	7.3M	4.8M	+100.00%
Jun 30, 2025	BURKEHILL GLOBAL MANAGEMENT, LP	3.07%	1.9M	2.89M	1.9M	+100.00%
Jun 30, 2025	RAIFFEISEN BANK INTERNATIONAL AG	0.48%	300K	531K	0	0
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.2%	123.63K	187.91K	65.85K	+113.96%
Jun 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.2%	126.1K	191.67K	115.2K	+1,056.88%
Jun 30, 2025	HRT FINANCIAL LP	0.2%	124.4K	189K	124.4K	+100.00%
Jun 30, 2025	XTX TOPCO LTD	0.16%	97.26K	147.84K	97.26K	+100.00%
Jun 30, 2025	THRIVENT FINANCIAL FOR LUTHERANS	0.15%	95.33K	145K	0	0
Jun 30, 2025	TD ASSET MANAGEMENT INC	0.14%	88.6K	134.67K	0	0
Jun 30, 2025	INVESCO LTD.	0.14%	84.83K	128.94K	23.16K	+37.55%
Jun 30, 2025	CANTOR FITZGERALD, L. P.	0.86%	532.5K	809.4K	-952.09K	-64.13%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0.81%	498.24K	757.33K	-485.85K	-49.37%
Jun 30, 2025	UBS GROUP AG	0.76%	472.04K	717.5K	-18.16K	-3.70%
Jun 30, 2025	TWO SIGMA ADVISERS, LP	0.67%	413.6K	628.67K	-57.9K	-12.28%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.57%	353.31K	537.03K	22.77K	+6.89%
Jun 30, 2025	FEDERATED HERMES, INC.	0.56%	344.54K	523.7K	1.13K	+0.33%
Jun 30, 2025	CITIGROUP INC	0.1%	62.5K	95K	31.04K	+98.65%
Jun 30, 2025	JANE STREET GROUP, LLC	0.13%	79.3K	120.54K	79.3K	+100.00%
Jun 30, 2025	SQUAREPOINT OPS LLC	0.12%	71.44K	108.59K	71.44K	+100.00%
Jun 30, 2025	TWO SIGMA INVESTMENTS, LP	0.41%	252.36K	383.58K	-69.05K	-21.48%
Mar 31, 2025	AXA S.A.	0.55%	270.08K	374.06K	-346	-0.13%
Mar 31, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.12%	57.04K	79K	765	+1.36%
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	0.34%	168.9K	233.93K	-342.71K	-66.99%
Mar 31, 2025	PRUDENTIAL FINANCIAL INC	0.58%	287.49K	398.17K	680	+0.24%
Mar 31, 2025	SCHONFELD STRATEGIC ADVISORS LLC	3.36%	1.66M	2.3M	1.66M	+100.00%
Mar 31, 2025	TD ASSET MANAGEMENT INC	0.18%	88.6K	122.71K	0	0
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.67%	330.54K	457.8K	-180.97K	-35.38%
Mar 31, 2025	JENNISON ASSOCIATES LLC	4.91%	2.43M	3.37M	-78.33K	-3.12%
Mar 31, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	5.57%	2.76M	3.82M	0	0
Mar 31, 2025	HEALTHINVEST PARTNERS AB	0.37%	182.35K	252.56K	-65.1K	-26.31%
Mar 31, 2025	JPMORGAN CHASE & CO	0.51%	251.44K	348.24K	-7.96K	-3.07%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.3%	1.14M	1.58M	30.6K	+2.75%
Mar 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.12%	57.78K	80.03K	-374.16K	-86.62%
Mar 31, 2025	UBS GROUP AG	0.99%	490.2K	678.93K	55.64K	+12.80%
Mar 31, 2025	THRIVENT FINANCIAL FOR LUTHERANS	0.19%	95.33K	132K	0	0
Mar 31, 2025	CITADEL ADVISORS LLC	0.27%	134.3K	186.01K	66.3K	+97.50%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.32%	159.87K	221.41K	50.61K	+46.32%
Mar 31, 2025	ACADIAN ASSET MANAGEMENT LLC	1.38%	682.67K	942K	182.41K	+36.46%
Mar 31, 2025	FEDERATED HERMES, INC.	0.69%	343.41K	475.62K	196.06K	+133.06%
Mar 31, 2025	NORTHERN TRUST CORP	0.81%	399.77K	553.68K	17.61K	+4.61%
Mar 31, 2025	SUPERSTRING CAPITAL MANAGEMENT LP	0.93%	458.97K	635.68K	-363.32K	-44.18%
Mar 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	0.99%	489.32K	678K	-34.77K	-6.63%
Mar 31, 2025	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	1.72%	850K	1.18M	350K	+70.00%
Mar 31, 2025	MORGAN STANLEY	3.45%	1.71M	2.37M	269.72K	+18.74%
Mar 31, 2025	BANK OF NEW YORK MELLON CORP	0.31%	155.17K	214.92K	14.03K	+9.94%
Mar 31, 2025		0.61%	300K	465K	80K	+36.36%
Mar 31, 2025	TWO SIGMA ADVISERS, LP	0.95%	471.5K	653.03K	-360.4K	-43.32%
Mar 31, 2025	STATE STREET CORP	1.9%	938.72K	1.3M	740	+0.08%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	1.99%	984.1K	1.36M	437.63K	+80.09%
Mar 31, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	8.02%	3.97M	5.5M	-103.98K	-2.55%
Mar 31, 2025	FRED ALGER MANAGEMENT, LLC	0.96%	477.21K	660.94K	-1.84M	-79.40%
Mar 31, 2025	VANGUARD GROUP INC	5.74%	2.84M	3.94M	-23.48K	-0.82%
Mar 31, 2025	BLACKROCK, INC.	6.97%	3.45M	4.78M	54.89K	+1.62%
Mar 31, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	7.34%	3.63M	5.03M	0	0
Mar 31, 2025	TWO SIGMA INVESTMENTS, LP	0.65%	321.41K	445.15K	-430.48K	-57.25%
Mar 31, 2025	AQR CAPITAL MANAGEMENT LLC	0.15%	73.96K	102.43K	73.96K	+100.00%
Mar 31, 2025	ALLIANCEBERNSTEIN L.P.	0.13%	64.63K	89.51K	0	0
Mar 31, 2025	INVESCO LTD.	0.12%	61.68K	85.42K	48.18K	+357.06%
Mar 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.12%	61.41K	85.05K	9.45K	+18.20%
Mar 31, 2025	STIFEL FINANCIAL CORP	0.1%	49.55K	68.63K	7.93K	+19.05%
Mar 31, 2025	TCG CROSSOVER MANAGEMENT, LLC	0.18%	86.8K	120.21K	0	0
Mar 31, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.09%	45.68K	63.26K	-42K	-47.90%
Mar 31, 2025	COMERICA BANK	0.08%	41.6K	57.62K	39.86K	+2,292.12%
Mar 31, 2025	CALLAN FAMILY OFFICE, LLC	0.08%	41.6K	57.62K	41.6K	+100.00%
Mar 31, 2025	CANTOR FITZGERALD, L. P.	3%	1.48M	2.06M	1.38M	+1,384.59%
Mar 31, 2025	BARCLAYS PLC	0.11%	56.44K	79K	-15.18K	-21.19%
Mar 31, 2025	RHUMBLINE ADVISERS	0.12%	61.39K	85.01K	-2.03K	-3.21%
Mar 31, 2024	CREDIT SUISSE AG/	0.08%	33.39K	569.6K	0	0
Mar 31, 2024	ADVISOR GROUP HOLDINGS, INC.	0.08%	33.43K	570.15K	5.75K	+20.76%
Mar 31, 2024	LPL FINANCIAL LLC	0.09%	34.93K	595.96K	-2.71K	-7.19%
Mar 31, 2024	RHUMBLINE ADVISERS	0.11%	45.61K	778.03K	1.46K	+3.30%
Mar 31, 2024	CHURCHILL MANAGEMENT CORP	0.11%	46.61K	795.1K	-2.75K	-5.57%
Mar 31, 2024	NAN FUNG GROUP HOLDINGS LTD	0.12%	47.15K	804.38K	0	0
Mar 31, 2024	SKANDINAVISKA ENSKILDA BANKEN AB (PUBL)	0.12%	49.56K	845.55K	49.56K	+100.00%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.13%	52.23K	891.1K	-444	-0.84%
Mar 31, 2024	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.13%	53.34K	910K	53.34K	+100.00%
Mar 31, 2024	PROFUND ADVISORS LLC	0.13%	54.43K	928.53M	20.57K	+60.75%
Mar 31, 2024	RENAISSANCE TECHNOLOGIES LLC	0.14%	59K	1.01M	59K	+100.00%
Mar 31, 2024	SWISS NATIONAL BANK	0.14%	59.2K	1.01M	8.2K	+16.08%
Mar 31, 2024	STATE STREET CORP	9.14%	3.74M	63.83M	1.15M	+44.21%
Mar 31, 2024	JENNISON ASSOCIATES LLC	8.36%	3.42M	58.4M	1.8M	+110.43%
Mar 31, 2024	POINT72 ASSET MANAGEMENT, L.P.	0.69%	282.65K	4.82M	-2.02K	-0.71%
Mar 31, 2024	GHOST TREE CAPITAL, LLC	0.92%	375K	6.4M	225K	+150.00%
Mar 31, 2024	DUQUESNE FAMILY OFFICE LLC	1.02%	417K	7.11M	417K	+100.00%
Mar 31, 2024	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	1.04%	425K	7.25M	-95K	-18.27%
Mar 31, 2024	CAPTION MANAGEMENT, LLC	1.04%	425K	7.25M	325K	+325.00%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	1.04%	425.17K	7.25M	187.04K	+78.54%
Mar 31, 2024	SOFINNOVA INVESTMENTS, INC.	1.05%	429.75K	7.33M	351	+0.08%
Mar 31, 2024	REDMILE GROUP, LLC	1.08%	442.83K	7.55M	-931.36K	-67.78%
Mar 31, 2024	MILLENNIUM MANAGEMENT LLC	1.12%	459.37K	7.84M	459.37K	+100.00%
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	1.5%	612.4K	10.45M	84.63K	+16.04%
Mar 31, 2024	SATURN V CAPITAL MANAGEMENT LLC	0.42%	173.17K	2.95M	173.17K	+100.00%
Mar 31, 2024	AXA S.A.	0.44%	178.16K	3.04M	178.16K	+100.00%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.48%	198.04K	3.38M	-43.75K	-18.09%
Mar 31, 2024	IKARIAN CAPITAL, LLC	0.49%	200K	3.41M	0	0
Mar 31, 2024	CANDRIAM S.C.A.	0.49%	200K	3.41M	200K	+100.00%
Mar 31, 2024	UBS GROUP AG	0.51%	209.48K	3.57M	70.83K	+51.09%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.58%	238.1K	4.06M	77.58K	+48.33%
Mar 31, 2024	WOODLINE PARTNERS LP	0.59%	242.66K	4.14M	1.21K	+0.50%
Mar 31, 2024	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.68%	278.12K	4.74M	41.72K	+17.65%
Mar 31, 2024	SUPERSTRING CAPITAL MANAGEMENT LP	0.71%	290.8K	4.96M	290.8K	+100.00%
Mar 31, 2024	SCHONFELD STRATEGIC ADVISORS LLC	0.78%	317.52K	5.42M	65.91K	+26.19%
Mar 31, 2024	RAFFERTY ASSET MANAGEMENT, LLC	0.87%	354.42K	6.05M	145.16K	+69.37%
Mar 31, 2024	VICTORY CAPITAL MANAGEMENT INC	0.91%	371.62K	6.34M	-32.3K	-8.00%
Mar 31, 2024	QUBE RESEARCH & TECHNOLOGIES LTD	1.06%	434.5K	7.41M	382.3K	+732.39%
Mar 31, 2024	STEMPOINT CAPITAL LP	1.22%	500K	1.08M	500K	+100.00%
Mar 31, 2024	ALKEON CAPITAL MANAGEMENT LLC	1.22%	500K	8.53M	140K	+38.89%
Mar 31, 2024	INVESCO LTD.	1.82%	744.78K	12.71M	-653.17K	-46.72%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	1.89%	773.09K	13.19M	19.91K	+2.64%
Mar 31, 2024	MORGAN STANLEY	2.16%	885.7K	15.11M	498.32K	+128.64%
Mar 31, 2024	WELLINGTON MANAGEMENT GROUP LLP	2.46%	1.01M	17.2M	468.38K	+86.76%
Mar 31, 2024	COMMODORE CAPITAL LP	2.69%	1.1M	18.77M	-800K	-42.11%
Mar 31, 2024	CORMORANT ASSET MANAGEMENT, LP	2.69%	1.1M	18.77M	1.1M	+100.00%
Mar 31, 2024	POLAR CAPITAL HOLDINGS PLC	3.05%	1.25M	21.33M	0	0
Mar 31, 2024	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	3.07%	1.26M	21.47M	-749.08K	-37.31%
Mar 31, 2024	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	3.95%	1.62M	27.59M	-382.64K	-19.13%
Mar 31, 2024	PERCEPTIVE ADVISORS LLC	4.19%	1.72M	29.29M	-286.4K	-14.30%
Mar 31, 2024	VANGUARD GROUP INC	5.56%	2.28M	38.83M	144.29K	+6.77%
Mar 31, 2024	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	6.03%	2.47M	42.15M	637.64K	+34.79%
Mar 31, 2024	ADAGE CAPITAL PARTNERS GP, L.L.C.	7.42%	3.04M	51.81M	-230K	-7.04%
Mar 31, 2024	BLACKROCK INC.	9.91%	4.06M	69.21M	-351.89K	-7.98%
Mar 31, 2024	DIMENSIONAL FUND ADVISORS LP	0.06%	25.38K	432.9K	0	0
Mar 31, 2024	BLAIR WILLIAM & CO/IL	0.07%	27.3K	465.74K	8.76K	+47.27%
Mar 31, 2024	QUEST PARTNERS LLC	0.08%	30.88K	526.75K	30.88K	+100.00%
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	0.08%	31.31K	534.15K	-62.02K	-66.45%
Mar 31, 2024	ENVESTNET ASSET MANAGEMENT INC	0.08%	32.56K	555.54K	-517	-1.56%
Mar 31, 2024	ALPHACENTRIC ADVISORS LLC	0.16%	65K	1.11M	65K	+100.00%
Mar 31, 2024	PRUDENTIAL FINANCIAL INC	0.17%	69.22K	1.18M	0	0
Mar 31, 2024	TREXQUANT INVESTMENT LP	0.17%	69.42K	1.18M	69.42K	+100.00%
Mar 31, 2024	HAP TRADING, LLC	0.18%	75K	363.75K	75K	+100.00%
Mar 31, 2024	HEALTHINVEST PARTNERS AB	0.19%	77.54K	1.32M	56.54K	+269.24%
Mar 31, 2024	WESTWOOD HOLDINGS GROUP INC	0.2%	82.23K	1.4M	82.23K	+100.00%
Mar 31, 2024	NEW YORK STATE COMMON RETIREMENT FUND	0.2%	82.39K	1.41M	57.2K	+227.05%
Mar 31, 2024	CRESTLINE MANAGEMENT, LP	0.21%	85K	1.45M	85K	+100.00%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.23%	93.53K	1.6M	-2.79K	-2.89%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.08%	33.8K	576.63K	33.8K	+100.00%
Mar 31, 2024	TD ASSET MANAGEMENT INC	0.31%	127.03K	2.17B	33.4K	+35.67%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.36%	146.06K	2.49M	-10.89K	-6.94%
Mar 31, 2024	NEUBERGER BERMAN GROUP LLC	0.4%	164.61K	2.81M	164.61K	+100.00%
Mar 31, 2024	CITIGROUP INC	0.74%	301.89K	5.15M	215.34K	+248.82%
Mar 31, 2024	NORTHERN TRUST CORP	0.74%	304.16K	5.19M	-6.51K	-2.10%
Mar 31, 2024	ENSIGN PEAK ADVISORS, INC	0.81%	330.93K	5.65M	212.92K	+180.44%
Mar 31, 2024	ARTISAN PARTNERS LIMITED PARTNERSHIP	0.82%	334.81K	5.71M	334.81K	+100.00%
Mar 31, 2024	VR ADVISER, LLC	3.82%	1.56M	26.68M	-1M	-39.00%
Mar 31, 2024	LYNX1 CAPITAL MANAGEMENT LP	5.09%	2.08M	35.54M	-27.43K	-1.30%
Mar 31, 2024	FRED ALGER MANAGEMENT, LLC	7.6%	3.11M	53.06M	-216.82K	-6.52%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.79%	753.18K	17.1M	61.3K	+8.86%
Dec 31, 2023	NORTHERN TRUST CORP	0.74%	310.67K	7.05M	10.9K	+3.64%
Dec 31, 2023	POINT72 ASSET MANAGEMENT, L.P.	0.68%	284.67K	6.46M	284.67K	+100.00%
Dec 31, 2023	SCHONFELD STRATEGIC ADVISORS LLC	0.6%	251.62K	5.71M	251.62K	+100.00%
Dec 31, 2023	NUVEEN ASSET MANAGEMENT, LLC	0.57%	241.79K	5.49M	105.81K	+77.81%
Dec 31, 2023	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	4.75%	2M	45.4M	0	0
Dec 31, 2023	PERCEPTIVE ADVISORS LLC	4.76%	2M	45.47M	870.57K	+76.87%
Dec 31, 2023	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	4.77%	2.01M	45.58M	-332.39K	-14.20%
Dec 31, 2023	LYNX1 CAPITAL MANAGEMENT LP	5.01%	2.11M	47.91M	4.4K	+0.21%
Dec 31, 2023	VANGUARD GROUP INC	5.06%	2.13M	48.39M	163.82K	+8.32%
Dec 31, 2023	WOODLINE PARTNERS LP	0.57%	241.45K	5.48M	107.27K	+79.94%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.57%	238.14K	5.41M	-61.92K	-20.63%
Dec 31, 2023	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.56%	236.4K	5.37M	225.64K	+2,096.62%
Dec 31, 2023	IKARIAN CAPITAL, LLC	0.47%	200K	4.54M	200K	+100.00%
Dec 31, 2023	RAFFERTY ASSET MANAGEMENT, LLC	0.5%	209.26K	4.75M	91.11K	+77.12%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.38%	160.52K	3.64M	19.33K	+13.69%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.37%	156.95K	3.56M	11.49K	+7.90%
Dec 31, 2023	GHOST TREE CAPITAL, LLC	0.36%	150K	3.41M	150K	+100.00%
Dec 31, 2023	VR ADVISER, LLC	6.09%	2.56M	58.2M	590.7K	+29.94%
Dec 31, 2023	STATE STREET CORP	6.16%	2.59M	58.89M	1.06M	+69.26%
Dec 31, 2023	ADAGE CAPITAL PARTNERS GP, L.L.C.	7.76%	3.27M	74.15M	0	0
Dec 31, 2023	FRED ALGER MANAGEMENT, LLC	7.9%	3.33M	75.53M	-932.32K	-21.89%
Dec 31, 2023	BLACKROCK INC.	10.47%	4.41M	100.08M	1.97M	+80.53%
Dec 31, 2023	UBS GROUP AG	0.33%	138.65K	3.15M	103.66K	+296.32%
Dec 31, 2023	BARCLAYS PLC	0.31%	129.07K	2.93M	64.49K	+99.85%
Dec 31, 2023	ENSIGN PEAK ADVISORS, INC	0.28%	118K	2.68M	118K	+100.00%
Dec 31, 2023	CAPTION MANAGEMENT, LLC	0.24%	100K	2.27M	100K	+100.00%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.23%	96.31K	2.19M	305	+0.32%
Dec 31, 2023	WELLINGTON MANAGEMENT GROUP LLP	1.28%	539.88K	12.26M	539.88K	+100.00%
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	1.25%	527.77K	11.98M	512.45K	+3,346.07%
Dec 31, 2023	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	1.23%	520K	11.8M	190K	+57.58%
Dec 31, 2023	TCG CROSSOVER MANAGEMENT, LLC	1.16%	486.8K	11.05M	0	0
Dec 31, 2023		0.42%	175.36K	3.98M	175.36K	+100.00%
Dec 31, 2023	SOFINNOVA INVESTMENTS, INC.	1.02%	429.4K	9.75M	429.4K	+100.00%
Dec 31, 2023	VICTORY CAPITAL MANAGEMENT INC	0.96%	403.93K	9.17M	337.28K	+506.04%
Dec 31, 2023	MORGAN STANLEY	0.92%	387.38K	8.79M	165.37K	+74.48%
Dec 31, 2023	ALKEON CAPITAL MANAGEMENT LLC	0.85%	360K	8.17M	360K	+100.00%
Dec 31, 2023	TD ASSET MANAGEMENT INC	0.22%	93.63K	2.13M	93.63K	+100.00%
Dec 31, 2023	ROYAL BANK OF CANADA	0.23%	96.96K	2.2M	-7.81K	-7.45%
Dec 31, 2023	POLAR CAPITAL HOLDINGS PLC	2.97%	1.25M	28.38M	1.25M	+100.00%
Dec 31, 2023	REDMILE GROUP, LLC	3.26%	1.37M	31.19M	-400.06K	-22.55%
Dec 31, 2023	INVESCO LTD.	3.32%	1.4M	31.73M	543.9K	+63.69%
Dec 31, 2023	JENNISON ASSOCIATES LLC	3.86%	1.63M	36.92M	204.26K	+14.36%
Dec 31, 2023	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	4.35%	1.83M	41.61M	1.83M	+100.00%
Dec 31, 2023	COMMODORE CAPITAL LP	4.51%	1.9M	43.13M	-625.75K	-24.77%
Dec 31, 2023	HOLOCENE ADVISORS, LP	4.56%	1.92M	43.59M	737.28K	+62.32%
Dec 31, 2023	BLACKSTONE INC.	0.83%	347.49K	7.89M	347.49K	+100.00%

Insiders

Among the CABA insiders holding of 1.65% of the stake in company, NICHTBERGER STEVEN, President & CEO, holds the largest shares of 1.03M. FLYNN JAMES E, 10 percent owner, is the second largest CABA insider with ownership of 700K shares. 5AM VENTURES V, L.P., 10 percent owner, stands third with possession of 333.14K shares of that stake.

Insiders	Designation	Shares Held
NICHTBERGER STEVEN	President & CEO	1.03M
FLYNN JAMES E	10 percent owner	700K
5AM VENTURES V, L.P.	10 percent owner	333.14K
SIMON MARK	director	147.21K
MARDA ANUP	Chief Financial Officer	50K
BINDER GWENDOLYN	President, Science & Tech.	31.31K
TOMASELLO SHAWN	director	22.73K
GAVEL STEVE	Chief Commercial Officer	22.17K
CHANG DAVID J.	Chief Medical Officer	8.8K
GERARD MICHAEL	General Counsel	6.6K
BOLLARD CATHERINE	director	5.41K

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Jan 21, 2026	CHANG DAVID J.	PURCHASE	2.26	8.8K	19.89K	8.8K
Jan 21, 2026	NICHTBERGER STEVEN	PURCHASE	2.24	45K	100.78K	1.03M
Jan 21, 2026	BOLLARD CATHERINE	PURCHASE	2.27	4.41K	9.98K	5.41K
Jan 21, 2026	SIMON MARK	PURCHASE	2.28	11.06K	25.26K	147.21K
Jan 21, 2026	GAVEL STEVE	PURCHASE	2.27	22.17K	50.22K	22.17K
Jan 21, 2026	TOMASELLO SHAWN	PURCHASE	2.21	22.73K	50.32K	22.73K
Jan 21, 2026	BINDER GWENDOLYN	PURCHASE	2.19	11.31K	24.76K	31.31K
Jan 21, 2026	GERARD MICHAEL	PURCHASE	2.27	6.6K	14.98K	6.6K
Jan 19, 2024	BINDER GWENDOLYN	SALE	20.33	700	14.23K	20K
Dec 19, 2023	BINDER GWENDOLYN	SALE	22.22	3.13K	69.59K	20K
Nov 20, 2023	BINDER GWENDOLYN	SALE	18.02	7.46K	134.41K	20K
Oct 19, 2023	BINDER GWENDOLYN	SALE	14.28	408	5.82K	20K
Sep 19, 2023	BINDER GWENDOLYN	SALE	18.50	700	12.95K	20K
Aug 21, 2023	BINDER GWENDOLYN	SALE	13.82	300	4.15K	20K
Jul 19, 2023	BINDER GWENDOLYN	SALE	14.26	2.82K	40.14K	20K
Jun 20, 2023	BINDER GWENDOLYN	SALE	12.99	11K	142.93K	20K
May 19, 2023	BINDER GWENDOLYN	SALE	11.81	22K	259.83K	20K
Oct 19, 2022	NICHTBERGER STEVEN	PURCHASE	1.25	8.13K	10.15K	986.48K
Oct 18, 2022	SIMON MARK	PURCHASE	0.98	7K	6.83K	7K
Oct 18, 2022	BINDER GWENDOLYN	PURCHASE	0.99	20K	19.89K	20K
Oct 18, 2022	BOLLARD CATHERINE	PURCHASE	0.99	1K	993.5	1K
Oct 18, 2022	MARDA ANUP	PURCHASE	0.99	50K	49.62K	50K
Oct 18, 2022	NICHTBERGER STEVEN	PURCHASE	0.99	141.87K	141.01K	978.36K
Nov 01, 2021	5AM VENTURES V, L.P.	SALE	13.00	36.54K	475.07K	333.14K
Sep 07, 2021	5AM VENTURES V, L.P.	SALE	9.70	625K	6.06M	1.99M
Jan 12, 2021	5AM VENTURES V, L.P.	SALE	13.00	10.53K	136.89K	369.69K
Jan 08, 2021	5AM VENTURES V, L.P.	SALE	13.00	37.41K	486.34K	380.22K
Dec 10, 2020	5AM VENTURES V, L.P.	SALE	14.75	36.92K	544.51K	417.63K
Oct 29, 2019	5AM VENTURES V, L.P.	PURCHASE	11.00	454.55K	5M	454.55K
Oct 29, 2019	FLYNN JAMES E	PURCHASE	11.00	700K	7.7M	700K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE132.07K8

SALES00

NET SHARES132.07K8

SHARES HELD1.28M8

% NET SHARES-89.65%0%

Frequently Asked Questions

Stock Outstanding Shares

ShortableYes

OptionableYes

Short Percent Of Outstanding Shares6.37

Short Percent Of Float6.48

Shares Outstanding91.47M

Shares Float61.64M

Shares Short5.82M

Short Ratio4.6

6.48%

Short % of Float

6.37%

Short % of Shares Outstanding

Market Insider

Investors cannot turn a blind eye to insiders as well as institutional ownership. They need to follow insider trades to determine the direction the stock is likely to take.

Major Holders Summary

1.65% Percentage of Shares held by All Insiders

79.8% Percentage of Shares held by All Institutions

81.14% Percentage of Float held by Institutions

116

Number of Institutions Holding Shares

Institutional Ownership

Date	Holder	% Stake	Shares Held	Total Value ($)	Shares	% Change in Portfolio
Dec 31, 2025	BARCLAYS PLC	0.22%	220.7K	483.32K	217.61K	+7,058.48%
Dec 31, 2025	NORTHERN TRUST CORP	0.23%	238.44K	522.19K	11.46K	+5.05%
Dec 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.14%	138.28K	302.84K	-233.83K	-62.84%
Dec 31, 2025	BOOTHBAY FUND MANAGEMENT, LLC	0.24%	243.45K	533.15K	243.45K	+100.00%
Dec 31, 2025	NISA INVESTMENT ADVISORS, LLC	0%	811	1.78K	0	0
Dec 31, 2025	FLAGSHIP HARBOR ADVISORS, LLC	0%	1K	2.19K	1K	+100.00%
Dec 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0%	1.64K	3.59K	-191	-10.43%
Dec 31, 2025	GF FUND MANAGEMENT CO. LTD.	0%	1.89K	4.14K	1.89K	+100.00%
Dec 31, 2025	WELLS FARGO & COMPANY/MN	0%	2K	4.38K	-1K	-33.33%
Dec 31, 2025	PNC FINANCIAL SERVICES GROUP, INC.	0%	4.6K	10.07K	4K	+666.67%
Dec 31, 2025	MIRAE ASSET GLOBAL INVESTMENTS CO., LTD.	0%	4.68K	10.25K	4.68K	+100.00%
Dec 31, 2025	JPMORGAN CHASE & CO	0.01%	9.81K	21.47K	-527.84K	-98.18%
Dec 31, 2025	HB WEALTH MANAGEMENT, LLC	0.01%	10K	21.9K	10K	+100.00%
Dec 31, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.01%	13.01K	28.04K	-73	-0.56%
Dec 31, 2025	CRA FINANCIAL SERVICES, LLC	0.01%	15K	32.85K	0	0
Dec 31, 2025	CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD.	0.02%	15.69K	34.35K	15.69K	+100.00%
Dec 31, 2025	ANTIPODES PARTNERS LTD	0.02%	17.19K	37.64K	17.19K	+100.00%
Dec 31, 2025	CLEAR HARBOR ASSET MANAGEMENT, LLC	0.02%	19.5K	42.71K	19.5K	+100.00%
Dec 31, 2025	LPL FINANCIAL LLC	0.04%	42.62K	93.33K	42.62K	+100.00%
Dec 31, 2025	BANK OF NEW YORK MELLON CORP	0.05%	54.05K	118.36K	6.24K	+13.05%
Dec 31, 2025	MATAURO, LLC	0.05%	55.11K	120.69K	55.11K	+100.00%
Dec 31, 2025	AMERICAN CENTURY COMPANIES INC	0.06%	58.78K	128.72K	46.75K	+388.51%
Dec 31, 2025	DYNAMIC TECHNOLOGY LAB PRIVATE LTD	0.07%	66.79K	146K	66.79K	+100.00%
Dec 31, 2025	CITIGROUP INC	0.07%	73.77K	161.57K	73.42K	+20,858.52%
Dec 31, 2025	TD ASSET MANAGEMENT INC	0.09%	88.6K	194.03K	0	0
Dec 31, 2025	LETKO, BROSSEAU & ASSOCIATES INC	0.09%	90.48K	198.14K	90.48K	+100.00%
Dec 31, 2025	GOLDMAN SACHS GROUP INC	0.24%	246.5K	539.84K	246.5K	+100.00%
Dec 31, 2025	RAIFFEISEN BANK INTERNATIONAL AG	0.44%	450K	967.5K	100K	+28.57%
Dec 31, 2025	BLACKROCK, INC.	2.28%	2.33M	5.1M	707.6K	+43.66%
Dec 31, 2025	VANGUARD GROUP INC	4.32%	4.42M	9.68M	228.7K	+5.46%
Dec 31, 2025	JENNISON ASSOCIATES LLC	8.71%	8.91M	19.5M	408.16K	+4.80%
Dec 31, 2025	ALMITAS CAPITAL LLC	0.38%	387.49K	848.61K	0	0
Dec 31, 2025	683 CAPITAL MANAGEMENT, LLC	0.38%	388.56K	850.95K	388.56K	+100.00%
Dec 31, 2025	STATE STREET CORP	0.42%	425.48K	931.8K	48.68K	+12.92%
Dec 31, 2025		0.49%	505.43K	1.11M	505.43K	+100.00%
Dec 31, 2025	BURKEHILL GLOBAL MANAGEMENT, LP	0.68%	700K	1.53M	0	0
Dec 31, 2025	TWO SIGMA ADVISERS, LP	0.72%	737.9K	1.62M	406.9K	+122.93%
Dec 31, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	8.63%	8.83M	19.34M	0	0
Dec 31, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	9.46%	9.68M	21.19M	0	0
Dec 31, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	9.64%	9.86M	21.59M	1.5M	+17.89%
Dec 31, 2025	RENAISSANCE TECHNOLOGIES LLC	1.49%	1.52M	3.33M	183.16K	+13.67%
Dec 31, 2025	TWO SIGMA INVESTMENTS, LP	1.8%	1.84M	4.03M	1.37M	+291.05%
Dec 31, 2025	MILLENNIUM MANAGEMENT LLC	2.68%	2.74M	5.99M	2.05M	+298.49%
Dec 31, 2025	XTX TOPCO LTD	0.15%	155.39K	340.3K	-128.91K	-45.34%
Dec 31, 2025	STONEPINE CAPITAL MANAGEMENT, LLC	0.17%	171.1K	374.71K	171.1K	+100.00%
Dec 31, 2025	HUDSON BAY CAPITAL MANAGEMENT LP	0.14%	138.73K	303.82K	138.73K	+100.00%
Dec 31, 2025	SQUAREPOINT OPS LLC	0.15%	149.09K	326.52K	137.23K	+1,156.27%
Dec 31, 2025	JANE STREET GROUP, LLC	0.18%	179.1K	392.23K	-11.1K	-5.84%
Dec 31, 2025	CITADEL ADVISORS LLC	0.22%	222.6K	487.49K	-22.2K	-9.07%
Dec 31, 2025	OMERS ADMINISTRATION CORP	0.09%	95.4K	208.93K	95.4K	+100.00%
Dec 31, 2025	SCHRODER INVESTMENT MANAGEMENT GROUP	0.74%	756.64K	1.63M	756.64K	+100.00%
Dec 31, 2025	IKARIAN CAPITAL, LLC	0.88%	900K	1.97M	900K	+100.00%
Dec 31, 2025	OPALEYE MANAGEMENT INC.	0.88%	900K	1.97M	91.12K	+11.26%
Dec 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.07%	1.09M	2.4M	-200.99K	-15.52%
Dec 31, 2025	JONES FINANCIAL COMPANIES LLLP	0.02%	20.66K	45.25K	653	+3.26%
Dec 31, 2025	VANGUARD PERSONALIZED INDEXING MANAGEMENT, LLC	0.02%	22.38K	49.02K	233	+1.05%
Dec 31, 2025	CALLAN FAMILY OFFICE, LLC	0.02%	22.58K	49.44K	22.58K	+100.00%
Dec 31, 2025	MERCER GLOBAL ADVISORS INC /ADV	0.03%	26.51K	58.06K	26.51K	+100.00%
Dec 31, 2025	TOWER RESEARCH CAPITAL LLC (TRC)	0.03%	30.35K	66.46M	25.98K	+594.87%
Dec 31, 2025	SG AMERICAS SECURITIES, LLC	0.03%	30.63K	67K	9.37K	+44.04%
Dec 31, 2025	LIGHTHOUSE INVESTMENT PARTNERS, LLC	0.04%	38.88K	85.15K	38.88K	+100.00%
Dec 31, 2025	JEFFERIES FINANCIAL GROUP INC.	0.04%	45.13K	98.82K	-2.38K	-5.00%
Dec 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.05%	50.82K	111.31K	0	0
Dec 31, 2025	GSA CAPITAL PARTNERS LLP	0.3%	303.99K	666K	303.99K	+100.00%
Dec 31, 2025	UBS GROUP AG	0.41%	415.68K	910.33K	10.56K	+2.61%
Dec 31, 2025	DIMENSIONAL FUND ADVISORS LP	0.44%	452.04K	989.97K	452.04K	+100.00%
Dec 31, 2025	ENSIGN PEAK ADVISORS, INC	0.54%	550K	1.2M	550K	+100.00%
Dec 31, 2025	PRIVATE ADVISOR GROUP, LLC	0.01%	14.73K	32.25K	14.73K	+100.00%
Dec 31, 2025	MARSHALL WACE, LLP	0.94%	959.08K	2.1M	-366.97K	-27.67%
Dec 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	1.06%	1.09M	2.38M	165.48K	+17.98%
Dec 31, 2025	MORGAN STANLEY	1.31%	1.34M	2.94M	-130.97K	-8.88%
Dec 31, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.13%	130.68K	286.18K	35K	+36.58%
Dec 31, 2025	GRAHAM CAPITAL MANAGEMENT, L.P.	0.15%	151.45K	331.68K	151.45K	+100.00%
Dec 31, 2025	SCHONFELD STRATEGIC ADVISORS LLC	1.18%	1.2M	2.64M	159.9K	+15.31%
Dec 31, 2025	WOODLINE PARTNERS LP	1.22%	1.25M	2.74M	-885.11K	-41.45%
Dec 31, 2025	SUPERSTRING CAPITAL MANAGEMENT LP	2.2%	2.25M	4.94M	709.03K	+45.91%
Dec 31, 2025	CORMORANT ASSET MANAGEMENT, LP	4.3%	4.4M	9.64M	-600K	-12.00%
Dec 31, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.32%	331.23K	725.38K	242.07K	+271.51%
Dec 31, 2025	INVESCO LTD.	0.19%	189.2K	414.34K	66.4K	+54.07%
Sep 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	1.27%	1.29M	3.03M	-892.09K	-40.79%
Sep 30, 2025	FRED ALGER MANAGEMENT, LLC	0.06%	59.81K	139.96K	0	0
Sep 30, 2025	NORTHERN TRUST CORP	0.22%	226.99K	531.15K	93.97K	+70.64%
Sep 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.36%	372.11K	870.73K	248.48K	+201.00%
Sep 30, 2025	TD ASSET MANAGEMENT INC	0.09%	88.6K	207.32K	0	0
Sep 30, 2025	QUBE RESEARCH & TECHNOLOGIES LTD	0.09%	89.16K	208.63K	89.16K	+100.00%
Sep 30, 2025	JEFFERIES FINANCIAL GROUP INC.	0.05%	47.5K	111.15K	-1.95M	-97.62%
Sep 30, 2025	BANK OF NEW YORK MELLON CORP	0.05%	47.81K	111.88K	0	0
Sep 30, 2025	ROYAL BANK OF CANADA	0.09%	91.72K	214K	91.72K	+100.00%
Sep 30, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.09%	95.68K	223.88K	50K	+109.47%
Sep 30, 2025	JANE STREET GROUP, LLC	0.1%	104.66K	244.91K	-133.66K	-56.08%
Sep 30, 2025	FEDERATED HERMES, INC.	0.11%	112.03K	262.15K	-232.51K	-67.48%
Sep 30, 2025	JPMORGAN CHASE & CO	0.87%	537.65K	1.26M	456.85K	+565.44%
Sep 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.9%	920.34K	2.15M	366.88K	+66.29%
Sep 30, 2025	ALYESKA INVESTMENT GROUP, L.P.	1.27%	1.3M	3.04M	-3.5M	-72.92%
Sep 30, 2025	RENAISSANCE TECHNOLOGIES LLC	1.31%	1.34M	3.13M	1.21M	+962.19%
Sep 30, 2025	BLACKROCK, INC.	1.59%	1.62M	3.79M	650.27K	+67.00%
Sep 30, 2025	STATE STREET CORP	0.37%	376.8K	881.71K	158.83K	+72.87%
Sep 30, 2025	UBS GROUP AG	0.4%	405.12K	947.98K	-66.92K	-14.18%
Sep 30, 2025	MARSHALL WACE, LLP	1.3%	1.33M	3.1M	1.14M	+594.42%
Sep 30, 2025	MORGAN STANLEY	1.44%	1.47M	3.45M	149.87K	+11.31%
Sep 30, 2025	SUPERSTRING CAPITAL MANAGEMENT LP	1.51%	1.54M	3.61M	483.76K	+45.60%
Sep 30, 2025	HEIGHTS CAPITAL MANAGEMENT, INC	2.04%	2.08M	4.88M	-1.06M	-33.71%
Sep 30, 2025	WOODLINE PARTNERS LP	2.09%	2.14M	5M	916.88K	+75.25%
Sep 30, 2025	CORMORANT ASSET MANAGEMENT, LP	4.89%	5M	11.7M	0	0
Sep 30, 2025	CRA FINANCIAL SERVICES, LLC	0.02%	15K	35.1K	4K	+36.36%
Sep 30, 2025	JONES FINANCIAL COMPANIES LLLP	0.03%	20.01K	47.22K	20.01K	+100.00%
Sep 30, 2025	SG AMERICAS SECURITIES, LLC	0.03%	21.26K	50K	-2.78K	-11.58%
Sep 30, 2025	VANGUARD PERSONALIZED INDEXING MANAGEMENT, LLC	0.04%	22.15K	51.83K	-2.8K	-11.21%
Sep 30, 2025	SUSQUEHANNA PORTFOLIO STRATEGIES, LLC	0.05%	33.94K	79.41K	33.94K	+100.00%
Sep 30, 2025	CUBIST SYSTEMATIC STRATEGIES, LLC	0.06%	37.74K	88.32K	-197.53K	-83.96%
Sep 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	8.63%	8.83M	20.66M	0	0
Sep 30, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	9.46%	9.68M	22.64M	0	0
Sep 30, 2025	CAPTION MANAGEMENT, LLC	0.24%	250K	585K	250K	+100.00%
Sep 30, 2025	BANK OF AMERICA CORP /DE/	0.43%	268.06K	627.26K	-230.19K	-46.20%
Sep 30, 2025	ALMITAS CAPITAL LLC	0.38%	387.49K	906.73K	20K	+5.44%
Sep 30, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	8.18%	8.36M	19.57M	1.57M	+23.09%
Sep 30, 2025	INVESCO LTD.	0.12%	122.8K	287.35K	37.97K	+44.76%
Sep 30, 2025	TWO SIGMA INVESTMENTS, LP	0.46%	470.48K	1.1M	218.12K	+86.43%
Sep 30, 2025	MILLENNIUM MANAGEMENT LLC	0.67%	686.81K	1.61M	-168.52K	-19.70%
Sep 30, 2025	VANGUARD GROUP INC	4.1%	4.19M	9.81M	740.03K	+21.45%
Sep 30, 2025	CITADEL ADVISORS LLC	0.24%	244.8K	572.83K	168.3K	+220.00%
Sep 30, 2025	GOLDMAN SACHS GROUP INC	0.27%	272.6K	637.87K	-80.71K	-22.84%
Sep 30, 2025	TWO SIGMA ADVISERS, LP	0.32%	331K	774.54K	-82.6K	-19.97%
Sep 30, 2025	TRUE WEALTH DESIGN, LLC	0%	0	-	-17	-100.00%
Sep 30, 2025	MID-AMERICAN WEALTH ADVISORY GROUP, INC.	0%	0	-	-91	-100.00%
Sep 30, 2025	CATALYST FUNDS MANAGEMENT PTY LTD	0%	0	-	-21K	-100.00%
Sep 30, 2025	BLUE OWL CAPITAL HOLDINGS LP	0%	0	-	-1.13M	-100.00%
Sep 30, 2025	EVERSOURCE WEALTH ADVISORS, LLC	0%	0	-	-41	-100.00%
Sep 30, 2025	MYDA ADVISORS LLC	0%	0	-	-40K	-100.00%
Sep 30, 2025	CWM, LLC	0%	0	-	-1.6K	-100.00%
Sep 30, 2025	CLEAR STREET MARKETS LLC	0%	0	-	-4.82K	-100.00%
Sep 30, 2025	SAVANT CAPITAL, LLC	0%	0	-	-12.47K	-100.00%
Sep 30, 2025	HUDSON BAY CAPITAL MANAGEMENT LP	0%	0	-	-13.07K	-100.00%
Sep 30, 2025	PRUDENTIAL FINANCIAL INC	0%	0	-	-284K	-100.00%
Sep 30, 2025	XTX TOPCO LTD	0.28%	284.3K	665.26K	187.04K	+192.31%
Sep 30, 2025	ACADIAN ASSET MANAGEMENT LLC	0.18%	186.52K	433K	171.38K	+1,131.89%
Sep 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.05%	50.82K	118.93K	203	+0.40%
Sep 30, 2025	QUADRATURE CAPITAL LTD	0.04%	42.91K	100.41K	42.91K	+100.00%
Sep 30, 2025	THRIVENT FINANCIAL FOR LUTHERANS	0%	0	-	-95.33K	-100.00%
Sep 30, 2025	OPTIVER HOLDING B.V.	0%	24	56	24	+100.00%
Sep 30, 2025	CITIGROUP INC	0%	352	824	-62.15K	-99.44%
Sep 30, 2025	BRYN MAWR TRUST CO	0%	450	1.05K	450	+100.00%
Sep 30, 2025	SBI SECURITIES CO., LTD.	0%	456	1.07K	-6.06K	-93.00%
Sep 30, 2025	PNC FINANCIAL SERVICES GROUP, INC.	0%	600	1.4K	-709	-54.16%
Sep 30, 2025	NISA INVESTMENT ADVISORS, LLC	0%	811	1.9K	-101	-11.07%
Sep 30, 2025	RUSSELL INVESTMENTS GROUP, LTD.	0%	939	2.2K	0	0
Sep 30, 2025	RISE ADVISORS, LLC	0%	1.08K	2.53K	0	0
Sep 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0%	1.83K	4.29K	-47.24K	-96.27%
Sep 30, 2025	WELLS FARGO & COMPANY/MN	0%	3K	7.02K	-3.69K	-55.13%
Sep 30, 2025	AMERICAN CENTURY COMPANIES INC	0.02%	12.03K	28.16K	12.03K	+100.00%
Sep 30, 2025	FMR LLC	0.02%	14.06K	32.91K	-1.39K	-9.01%
Sep 30, 2025	JENNISON ASSOCIATES LLC	8.31%	8.5M	19.88M	2.48M	+41.15%
Sep 30, 2025	SCHONFELD STRATEGIC ADVISORS LLC	1.02%	1.04M	2.44M	-440.67K	-29.68%
Sep 30, 2025	BARCLAYS PLC	0.01%	3.08K	7.22K	-6.65K	-68.34%
Sep 30, 2025	RAIFFEISEN BANK INTERNATIONAL AG	0.34%	350K	833K	50K	+16.67%
Sep 30, 2025	BURKEHILL GLOBAL MANAGEMENT, LP	0.68%	700K	1.64M	-1.2M	-63.16%
Sep 30, 2025	OPALEYE MANAGEMENT INC.	0.79%	808.88K	1.89M	808.88K	+100.00%
Jun 30, 2025	GEODE CAPITAL MANAGEMENT, LLC	0.89%	553.46K	841.55K	-587.84K	-51.51%
Jun 30, 2025	HEIGHTS CAPITAL MANAGEMENT, INC	5.08%	3.14M	4.78M	3.14M	+100.00%
Jun 30, 2025	PRICE T ROWE ASSOCIATES INC /MD/	3.53%	2.19M	3.33M	1.7M	+346.95%
Jun 30, 2025	PRUDENTIAL FINANCIAL INC	0.46%	284K	431.68K	-3.49K	-1.21%
Jun 30, 2025	AXA S.A.	0.44%	270.52K	411.18K	439	+0.16%
Jun 30, 2025	JPMORGAN CHASE & CO	0.13%	80.8K	122.81K	-170.64K	-67.87%
Jun 30, 2025	JEFFERIES FINANCIAL GROUP INC.	3.23%	2M	3.04M	2M	+100.00%
Jun 30, 2025	ANSON FUNDS MANAGEMENT LP	2.95%	1.82M	2.77M	1.82M	+100.00%
Jun 30, 2025	SCHONFELD STRATEGIC ADVISORS LLC	2.4%	1.48M	2.26M	-177.57K	-10.68%
Jun 30, 2025	MORGAN STANLEY	2.14%	1.32M	2.01M	-384.08K	-22.48%
Jun 30, 2025	WOODLINE PARTNERS LP	1.97%	1.22M	1.85M	1.22M	+100.00%
Jun 30, 2025	STATE STREET CORP	0.35%	217.97K	331.31K	-720.75K	-76.78%
Jun 30, 2025	MARSHALL WACE, LLP	0.31%	190.96K	290.26K	157.5K	+470.70%
Jun 30, 2025	NORTHERN TRUST CORP	0.22%	133.02K	202.19K	-266.75K	-66.73%
Jun 30, 2025	CITADEL ADVISORS LLC	0.12%	76.5K	116.28K	36K	+88.89%
Jun 30, 2025	VANGUARD GROUP INC	5.58%	3.45M	5.25M	606.49K	+21.32%
Jun 30, 2025	BLUE OWL CAPITAL HOLDINGS LP	1.82%	1.13M	1.71M	1.13M	+100.00%
Jun 30, 2025	SUPERSTRING CAPITAL MANAGEMENT LP	1.71%	1.06M	1.61M	601.79K	+131.12%
Jun 30, 2025	BLACKROCK, INC.	1.57%	970.6K	1.48M	-2.48M	-71.88%
Jun 30, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.08%	50.62K	76.94K	-109.25K	-68.34%
Jun 30, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	15.64%	9.68M	14.71M	6.92M	+250.51%
Jun 30, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	14.27%	8.83M	13.42M	5.2M	+142.94%
Jun 30, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	10.98%	6.79M	10.33M	2.82M	+71.13%
Jun 30, 2025	JENNISON ASSOCIATES LLC	9.73%	6.02M	9.15M	3.59M	+147.36%
Jun 30, 2025	SEI INVESTMENTS CO	0%	0	-	-12.18K	-100.00%
Jun 30, 2025	MILLENNIUM MANAGEMENT LLC	1.38%	855.33K	1.3M	686.43K	+406.42%
Jun 30, 2025	CUBIST SYSTEMATIC STRATEGIES, LLC	0.38%	235.27K	357.61K	235.27K	+100.00%
Jun 30, 2025		0.48%	300K	531K	0	0
Jun 30, 2025	ALMITAS CAPITAL LLC	0.59%	367.49K	558.59K	0	0
Jun 30, 2025	TCG CROSSOVER MANAGEMENT, LLC	0.14%	86.8K	131.93K	0	0
Jun 30, 2025	FRED ALGER MANAGEMENT, LLC	0.1%	59.81K	90.92K	-417.4K	-87.47%
Jun 30, 2025	BNP PARIBAS ARBITRAGE, SNC	0.08%	49.07K	74.58M	-12.34K	-20.09%
Jun 30, 2025	MYDA ADVISORS LLC	0.06%	40K	60.8K	40K	+100.00%
Jun 30, 2025	POINT72 ASIA (SINGAPORE) PTE. LTD.	0.06%	34.77K	52.85K	34.77K	+100.00%
Jun 30, 2025	AQR CAPITAL MANAGEMENT LLC	0.05%	32.13K	48.84M	-41.83K	-56.56%
Jun 30, 2025	VANGUARD PERSONALIZED INDEXING MANAGEMENT, LLC	0.04%	24.95K	37.92K	5.57K	+28.74%
Jun 30, 2025	TWO SIGMA SECURITIES, LLC	0.03%	16.49K	25.07K	16.49K	+100.00%
Jun 30, 2025	FMR LLC	0.03%	15.46K	23.49M	11.3K	+271.45%
Jun 30, 2025	ACADIAN ASSET MANAGEMENT LLC	0.02%	15.14K	23K	-667.53K	-97.78%
Jun 30, 2025	HUDSON BAY CAPITAL MANAGEMENT LP	0.02%	13.07K	19.87K	13.07K	+100.00%
Jun 30, 2025	DRW SECURITIES, LLC	0.02%	12.84K	19.52K	12.84K	+100.00%
Jun 30, 2025	SAVANT CAPITAL, LLC	0.02%	12.47K	18.96K	12.47K	+100.00%
Jun 30, 2025	CRA FINANCIAL SERVICES, LLC	0.02%	11K	16.72K	0	0
Jun 30, 2025	CLEAR STREET MARKETS LLC	0.01%	4.82K	7.33K	4.82K	+100.00%
Jun 30, 2025	POINT72 (DIFC) LTD	0%	2.43K	3.7K	2.43K	+100.00%
Jun 30, 2025	TRUVESTMENTS CAPITAL LLC	0%	1.97K	3K	0	0
Jun 30, 2025	RISE ADVISORS, LLC	0%	1.08K	1.65K	1.08K	+100.00%
Jun 30, 2025	FEDERATION DES CAISSES DESJARDINS DU QUEBEC	0%	340	517	0	0
Jun 30, 2025	MID-AMERICAN WEALTH ADVISORY GROUP, INC.	0%	91	138	91	+100.00%
Jun 30, 2025	EVERSOURCE WEALTH ADVISORS, LLC	0%	41	62	-49	-54.44%
Jun 30, 2025	TRUE WEALTH DESIGN, LLC	0%	17	26	-46	-73.02%
Jun 30, 2025	ROTHSCHILD INVESTMENT LLC	0%	0	-	-70	-100.00%
Jun 30, 2025	CORMORANT ASSET MANAGEMENT, LP	8.08%	5M	7.6M	5M	+100.00%
Jun 30, 2025	ALYESKA INVESTMENT GROUP, L.P.	7.76%	4.8M	7.3M	4.8M	+100.00%
Jun 30, 2025	BURKEHILL GLOBAL MANAGEMENT, LP	3.07%	1.9M	2.89M	1.9M	+100.00%
Jun 30, 2025	RAIFFEISEN BANK INTERNATIONAL AG	0.48%	300K	531K	0	0
Jun 30, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.2%	123.63K	187.91K	65.85K	+113.96%
Jun 30, 2025	RENAISSANCE TECHNOLOGIES LLC	0.2%	126.1K	191.67K	115.2K	+1,056.88%
Jun 30, 2025	HRT FINANCIAL LP	0.2%	124.4K	189K	124.4K	+100.00%
Jun 30, 2025	XTX TOPCO LTD	0.16%	97.26K	147.84K	97.26K	+100.00%
Jun 30, 2025	THRIVENT FINANCIAL FOR LUTHERANS	0.15%	95.33K	145K	0	0
Jun 30, 2025	TD ASSET MANAGEMENT INC	0.14%	88.6K	134.67K	0	0
Jun 30, 2025	INVESCO LTD.	0.14%	84.83K	128.94K	23.16K	+37.55%
Jun 30, 2025	CANTOR FITZGERALD, L. P.	0.86%	532.5K	809.4K	-952.09K	-64.13%
Jun 30, 2025	BANK OF AMERICA CORP /DE/	0.81%	498.24K	757.33K	-485.85K	-49.37%
Jun 30, 2025	UBS GROUP AG	0.76%	472.04K	717.5K	-18.16K	-3.70%
Jun 30, 2025	TWO SIGMA ADVISERS, LP	0.67%	413.6K	628.67K	-57.9K	-12.28%
Jun 30, 2025	GOLDMAN SACHS GROUP INC	0.57%	353.31K	537.03K	22.77K	+6.89%
Jun 30, 2025	FEDERATED HERMES, INC.	0.56%	344.54K	523.7K	1.13K	+0.33%
Jun 30, 2025	CITIGROUP INC	0.1%	62.5K	95K	31.04K	+98.65%
Jun 30, 2025	JANE STREET GROUP, LLC	0.13%	79.3K	120.54K	79.3K	+100.00%
Jun 30, 2025	SQUAREPOINT OPS LLC	0.12%	71.44K	108.59K	71.44K	+100.00%
Jun 30, 2025	TWO SIGMA INVESTMENTS, LP	0.41%	252.36K	383.58K	-69.05K	-21.48%
Mar 31, 2025	AXA S.A.	0.55%	270.08K	374.06K	-346	-0.13%
Mar 31, 2025	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.12%	57.04K	79K	765	+1.36%
Mar 31, 2025	MILLENNIUM MANAGEMENT LLC	0.34%	168.9K	233.93K	-342.71K	-66.99%
Mar 31, 2025	PRUDENTIAL FINANCIAL INC	0.58%	287.49K	398.17K	680	+0.24%
Mar 31, 2025	SCHONFELD STRATEGIC ADVISORS LLC	3.36%	1.66M	2.3M	1.66M	+100.00%
Mar 31, 2025	TD ASSET MANAGEMENT INC	0.18%	88.6K	122.71K	0	0
Mar 31, 2025	GOLDMAN SACHS GROUP INC	0.67%	330.54K	457.8K	-180.97K	-35.38%
Mar 31, 2025	JENNISON ASSOCIATES LLC	4.91%	2.43M	3.37M	-78.33K	-3.12%
Mar 31, 2025	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	5.57%	2.76M	3.82M	0	0
Mar 31, 2025	HEALTHINVEST PARTNERS AB	0.37%	182.35K	252.56K	-65.1K	-26.31%
Mar 31, 2025	JPMORGAN CHASE & CO	0.51%	251.44K	348.24K	-7.96K	-3.07%
Mar 31, 2025	GEODE CAPITAL MANAGEMENT, LLC	2.3%	1.14M	1.58M	30.6K	+2.75%
Mar 31, 2025	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.12%	57.78K	80.03K	-374.16K	-86.62%
Mar 31, 2025	UBS GROUP AG	0.99%	490.2K	678.93K	55.64K	+12.80%
Mar 31, 2025	THRIVENT FINANCIAL FOR LUTHERANS	0.19%	95.33K	132K	0	0
Mar 31, 2025	CITADEL ADVISORS LLC	0.27%	134.3K	186.01K	66.3K	+97.50%
Mar 31, 2025	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.32%	159.87K	221.41K	50.61K	+46.32%
Mar 31, 2025	ACADIAN ASSET MANAGEMENT LLC	1.38%	682.67K	942K	182.41K	+36.46%
Mar 31, 2025	FEDERATED HERMES, INC.	0.69%	343.41K	475.62K	196.06K	+133.06%
Mar 31, 2025	NORTHERN TRUST CORP	0.81%	399.77K	553.68K	17.61K	+4.61%
Mar 31, 2025	SUPERSTRING CAPITAL MANAGEMENT LP	0.93%	458.97K	635.68K	-363.32K	-44.18%
Mar 31, 2025	PRICE T ROWE ASSOCIATES INC /MD/	0.99%	489.32K	678K	-34.77K	-6.63%
Mar 31, 2025	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	1.72%	850K	1.18M	350K	+70.00%
Mar 31, 2025	MORGAN STANLEY	3.45%	1.71M	2.37M	269.72K	+18.74%
Mar 31, 2025	BANK OF NEW YORK MELLON CORP	0.31%	155.17K	214.92K	14.03K	+9.94%
Mar 31, 2025		0.61%	300K	465K	80K	+36.36%
Mar 31, 2025	TWO SIGMA ADVISERS, LP	0.95%	471.5K	653.03K	-360.4K	-43.32%
Mar 31, 2025	STATE STREET CORP	1.9%	938.72K	1.3M	740	+0.08%
Mar 31, 2025	BANK OF AMERICA CORP /DE/	1.99%	984.1K	1.36M	437.63K	+80.09%
Mar 31, 2025	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	8.02%	3.97M	5.5M	-103.98K	-2.55%
Mar 31, 2025	FRED ALGER MANAGEMENT, LLC	0.96%	477.21K	660.94K	-1.84M	-79.40%
Mar 31, 2025	VANGUARD GROUP INC	5.74%	2.84M	3.94M	-23.48K	-0.82%
Mar 31, 2025	BLACKROCK, INC.	6.97%	3.45M	4.78M	54.89K	+1.62%
Mar 31, 2025	ADAGE CAPITAL PARTNERS GP, L.L.C.	7.34%	3.63M	5.03M	0	0
Mar 31, 2025	TWO SIGMA INVESTMENTS, LP	0.65%	321.41K	445.15K	-430.48K	-57.25%
Mar 31, 2025	AQR CAPITAL MANAGEMENT LLC	0.15%	73.96K	102.43K	73.96K	+100.00%
Mar 31, 2025	ALLIANCEBERNSTEIN L.P.	0.13%	64.63K	89.51K	0	0
Mar 31, 2025	INVESCO LTD.	0.12%	61.68K	85.42K	48.18K	+357.06%
Mar 31, 2025	BNP PARIBAS ARBITRAGE, SNC	0.12%	61.41K	85.05K	9.45K	+18.20%
Mar 31, 2025	STIFEL FINANCIAL CORP	0.1%	49.55K	68.63K	7.93K	+19.05%
Mar 31, 2025	TCG CROSSOVER MANAGEMENT, LLC	0.18%	86.8K	120.21K	0	0
Mar 31, 2025	BRIDGEWAY CAPITAL MANAGEMENT, LLC	0.09%	45.68K	63.26K	-42K	-47.90%
Mar 31, 2025	COMERICA BANK	0.08%	41.6K	57.62K	39.86K	+2,292.12%
Mar 31, 2025	CALLAN FAMILY OFFICE, LLC	0.08%	41.6K	57.62K	41.6K	+100.00%
Mar 31, 2025	CANTOR FITZGERALD, L. P.	3%	1.48M	2.06M	1.38M	+1,384.59%
Mar 31, 2025	BARCLAYS PLC	0.11%	56.44K	79K	-15.18K	-21.19%
Mar 31, 2025	RHUMBLINE ADVISERS	0.12%	61.39K	85.01K	-2.03K	-3.21%
Mar 31, 2024	CREDIT SUISSE AG/	0.08%	33.39K	569.6K	0	0
Mar 31, 2024	ADVISOR GROUP HOLDINGS, INC.	0.08%	33.43K	570.15K	5.75K	+20.76%
Mar 31, 2024	LPL FINANCIAL LLC	0.09%	34.93K	595.96K	-2.71K	-7.19%
Mar 31, 2024	RHUMBLINE ADVISERS	0.11%	45.61K	778.03K	1.46K	+3.30%
Mar 31, 2024	CHURCHILL MANAGEMENT CORP	0.11%	46.61K	795.1K	-2.75K	-5.57%
Mar 31, 2024	NAN FUNG GROUP HOLDINGS LTD	0.12%	47.15K	804.38K	0	0
Mar 31, 2024	SKANDINAVISKA ENSKILDA BANKEN AB (PUBL)	0.12%	49.56K	845.55K	49.56K	+100.00%
Mar 31, 2024	MANUFACTURERS LIFE INSURANCE COMPANY, THE	0.13%	52.23K	891.1K	-444	-0.84%
Mar 31, 2024	EXODUSPOINT CAPITAL MANAGEMENT, LP	0.13%	53.34K	910K	53.34K	+100.00%
Mar 31, 2024	PROFUND ADVISORS LLC	0.13%	54.43K	928.53M	20.57K	+60.75%
Mar 31, 2024	RENAISSANCE TECHNOLOGIES LLC	0.14%	59K	1.01M	59K	+100.00%
Mar 31, 2024	SWISS NATIONAL BANK	0.14%	59.2K	1.01M	8.2K	+16.08%
Mar 31, 2024	STATE STREET CORP	9.14%	3.74M	63.83M	1.15M	+44.21%
Mar 31, 2024	JENNISON ASSOCIATES LLC	8.36%	3.42M	58.4M	1.8M	+110.43%
Mar 31, 2024	POINT72 ASSET MANAGEMENT, L.P.	0.69%	282.65K	4.82M	-2.02K	-0.71%
Mar 31, 2024	GHOST TREE CAPITAL, LLC	0.92%	375K	6.4M	225K	+150.00%
Mar 31, 2024	DUQUESNE FAMILY OFFICE LLC	1.02%	417K	7.11M	417K	+100.00%
Mar 31, 2024	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	1.04%	425K	7.25M	-95K	-18.27%
Mar 31, 2024	CAPTION MANAGEMENT, LLC	1.04%	425K	7.25M	325K	+325.00%
Mar 31, 2024	GOLDMAN SACHS GROUP INC	1.04%	425.17K	7.25M	187.04K	+78.54%
Mar 31, 2024	SOFINNOVA INVESTMENTS, INC.	1.05%	429.75K	7.33M	351	+0.08%
Mar 31, 2024	REDMILE GROUP, LLC	1.08%	442.83K	7.55M	-931.36K	-67.78%
Mar 31, 2024	MILLENNIUM MANAGEMENT LLC	1.12%	459.37K	7.84M	459.37K	+100.00%
Mar 31, 2024	PRICE T ROWE ASSOCIATES INC /MD/	1.5%	612.4K	10.45M	84.63K	+16.04%
Mar 31, 2024	SATURN V CAPITAL MANAGEMENT LLC	0.42%	173.17K	2.95M	173.17K	+100.00%
Mar 31, 2024	AXA S.A.	0.44%	178.16K	3.04M	178.16K	+100.00%
Mar 31, 2024	NUVEEN ASSET MANAGEMENT, LLC	0.48%	198.04K	3.38M	-43.75K	-18.09%
Mar 31, 2024	IKARIAN CAPITAL, LLC	0.49%	200K	3.41M	0	0
Mar 31, 2024	CANDRIAM S.C.A.	0.49%	200K	3.41M	200K	+100.00%
Mar 31, 2024	UBS GROUP AG	0.51%	209.48K	3.57M	70.83K	+51.09%
Mar 31, 2024	BANK OF AMERICA CORP /DE/	0.58%	238.1K	4.06M	77.58K	+48.33%
Mar 31, 2024	WOODLINE PARTNERS LP	0.59%	242.66K	4.14M	1.21K	+0.50%
Mar 31, 2024	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.68%	278.12K	4.74M	41.72K	+17.65%
Mar 31, 2024	SUPERSTRING CAPITAL MANAGEMENT LP	0.71%	290.8K	4.96M	290.8K	+100.00%
Mar 31, 2024	SCHONFELD STRATEGIC ADVISORS LLC	0.78%	317.52K	5.42M	65.91K	+26.19%
Mar 31, 2024	RAFFERTY ASSET MANAGEMENT, LLC	0.87%	354.42K	6.05M	145.16K	+69.37%
Mar 31, 2024	VICTORY CAPITAL MANAGEMENT INC	0.91%	371.62K	6.34M	-32.3K	-8.00%
Mar 31, 2024	QUBE RESEARCH & TECHNOLOGIES LTD	1.06%	434.5K	7.41M	382.3K	+732.39%
Mar 31, 2024	STEMPOINT CAPITAL LP	1.22%	500K	1.08M	500K	+100.00%
Mar 31, 2024	ALKEON CAPITAL MANAGEMENT LLC	1.22%	500K	8.53M	140K	+38.89%
Mar 31, 2024	INVESCO LTD.	1.82%	744.78K	12.71M	-653.17K	-46.72%
Mar 31, 2024	GEODE CAPITAL MANAGEMENT, LLC	1.89%	773.09K	13.19M	19.91K	+2.64%
Mar 31, 2024	MORGAN STANLEY	2.16%	885.7K	15.11M	498.32K	+128.64%
Mar 31, 2024	WELLINGTON MANAGEMENT GROUP LLP	2.46%	1.01M	17.2M	468.38K	+86.76%
Mar 31, 2024	COMMODORE CAPITAL LP	2.69%	1.1M	18.77M	-800K	-42.11%
Mar 31, 2024	CORMORANT ASSET MANAGEMENT, LP	2.69%	1.1M	18.77M	1.1M	+100.00%
Mar 31, 2024	POLAR CAPITAL HOLDINGS PLC	3.05%	1.25M	21.33M	0	0
Mar 31, 2024	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	3.07%	1.26M	21.47M	-749.08K	-37.31%
Mar 31, 2024	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	3.95%	1.62M	27.59M	-382.64K	-19.13%
Mar 31, 2024	PERCEPTIVE ADVISORS LLC	4.19%	1.72M	29.29M	-286.4K	-14.30%
Mar 31, 2024	VANGUARD GROUP INC	5.56%	2.28M	38.83M	144.29K	+6.77%
Mar 31, 2024	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	6.03%	2.47M	42.15M	637.64K	+34.79%
Mar 31, 2024	ADAGE CAPITAL PARTNERS GP, L.L.C.	7.42%	3.04M	51.81M	-230K	-7.04%
Mar 31, 2024	BLACKROCK INC.	9.91%	4.06M	69.21M	-351.89K	-7.98%
Mar 31, 2024	DIMENSIONAL FUND ADVISORS LP	0.06%	25.38K	432.9K	0	0
Mar 31, 2024	BLAIR WILLIAM & CO/IL	0.07%	27.3K	465.74K	8.76K	+47.27%
Mar 31, 2024	QUEST PARTNERS LLC	0.08%	30.88K	526.75K	30.88K	+100.00%
Mar 31, 2024	ALLIANCEBERNSTEIN L.P.	0.08%	31.31K	534.15K	-62.02K	-66.45%
Mar 31, 2024	ENVESTNET ASSET MANAGEMENT INC	0.08%	32.56K	555.54K	-517	-1.56%
Mar 31, 2024	ALPHACENTRIC ADVISORS LLC	0.16%	65K	1.11M	65K	+100.00%
Mar 31, 2024	PRUDENTIAL FINANCIAL INC	0.17%	69.22K	1.18M	0	0
Mar 31, 2024	TREXQUANT INVESTMENT LP	0.17%	69.42K	1.18M	69.42K	+100.00%
Mar 31, 2024	HAP TRADING, LLC	0.18%	75K	363.75K	75K	+100.00%
Mar 31, 2024	HEALTHINVEST PARTNERS AB	0.19%	77.54K	1.32M	56.54K	+269.24%
Mar 31, 2024	WESTWOOD HOLDINGS GROUP INC	0.2%	82.23K	1.4M	82.23K	+100.00%
Mar 31, 2024	NEW YORK STATE COMMON RETIREMENT FUND	0.2%	82.39K	1.41M	57.2K	+227.05%
Mar 31, 2024	CRESTLINE MANAGEMENT, LP	0.21%	85K	1.45M	85K	+100.00%
Mar 31, 2024	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.23%	93.53K	1.6M	-2.79K	-2.89%
Mar 31, 2024	SUSQUEHANNA INTERNATIONAL GROUP, LLP	0.08%	33.8K	576.63K	33.8K	+100.00%
Mar 31, 2024	TD ASSET MANAGEMENT INC	0.31%	127.03K	2.17B	33.4K	+35.67%
Mar 31, 2024	BANK OF NEW YORK MELLON CORP	0.36%	146.06K	2.49M	-10.89K	-6.94%
Mar 31, 2024	NEUBERGER BERMAN GROUP LLC	0.4%	164.61K	2.81M	164.61K	+100.00%
Mar 31, 2024	CITIGROUP INC	0.74%	301.89K	5.15M	215.34K	+248.82%
Mar 31, 2024	NORTHERN TRUST CORP	0.74%	304.16K	5.19M	-6.51K	-2.10%
Mar 31, 2024	ENSIGN PEAK ADVISORS, INC	0.81%	330.93K	5.65M	212.92K	+180.44%
Mar 31, 2024	ARTISAN PARTNERS LIMITED PARTNERSHIP	0.82%	334.81K	5.71M	334.81K	+100.00%
Mar 31, 2024	VR ADVISER, LLC	3.82%	1.56M	26.68M	-1M	-39.00%
Mar 31, 2024	LYNX1 CAPITAL MANAGEMENT LP	5.09%	2.08M	35.54M	-27.43K	-1.30%
Mar 31, 2024	FRED ALGER MANAGEMENT, LLC	7.6%	3.11M	53.06M	-216.82K	-6.52%
Dec 31, 2023	GEODE CAPITAL MANAGEMENT, LLC	1.79%	753.18K	17.1M	61.3K	+8.86%
Dec 31, 2023	NORTHERN TRUST CORP	0.74%	310.67K	7.05M	10.9K	+3.64%
Dec 31, 2023	POINT72 ASSET MANAGEMENT, L.P.	0.68%	284.67K	6.46M	284.67K	+100.00%
Dec 31, 2023	SCHONFELD STRATEGIC ADVISORS LLC	0.6%	251.62K	5.71M	251.62K	+100.00%
Dec 31, 2023	NUVEEN ASSET MANAGEMENT, LLC	0.57%	241.79K	5.49M	105.81K	+77.81%
Dec 31, 2023	BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC	4.75%	2M	45.4M	0	0
Dec 31, 2023	PERCEPTIVE ADVISORS LLC	4.76%	2M	45.47M	870.57K	+76.87%
Dec 31, 2023	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	4.77%	2.01M	45.58M	-332.39K	-14.20%
Dec 31, 2023	LYNX1 CAPITAL MANAGEMENT LP	5.01%	2.11M	47.91M	4.4K	+0.21%
Dec 31, 2023	VANGUARD GROUP INC	5.06%	2.13M	48.39M	163.82K	+8.32%
Dec 31, 2023	WOODLINE PARTNERS LP	0.57%	241.45K	5.48M	107.27K	+79.94%
Dec 31, 2023	GOLDMAN SACHS GROUP INC	0.57%	238.14K	5.41M	-61.92K	-20.63%
Dec 31, 2023	VOLORIDGE INVESTMENT MANAGEMENT, LLC	0.56%	236.4K	5.37M	225.64K	+2,096.62%
Dec 31, 2023	IKARIAN CAPITAL, LLC	0.47%	200K	4.54M	200K	+100.00%
Dec 31, 2023	RAFFERTY ASSET MANAGEMENT, LLC	0.5%	209.26K	4.75M	91.11K	+77.12%
Dec 31, 2023	BANK OF AMERICA CORP /DE/	0.38%	160.52K	3.64M	19.33K	+13.69%
Dec 31, 2023	BANK OF NEW YORK MELLON CORP	0.37%	156.95K	3.56M	11.49K	+7.90%
Dec 31, 2023	GHOST TREE CAPITAL, LLC	0.36%	150K	3.41M	150K	+100.00%
Dec 31, 2023	VR ADVISER, LLC	6.09%	2.56M	58.2M	590.7K	+29.94%
Dec 31, 2023	STATE STREET CORP	6.16%	2.59M	58.89M	1.06M	+69.26%
Dec 31, 2023	ADAGE CAPITAL PARTNERS GP, L.L.C.	7.76%	3.27M	74.15M	0	0
Dec 31, 2023	FRED ALGER MANAGEMENT, LLC	7.9%	3.33M	75.53M	-932.32K	-21.89%
Dec 31, 2023	BLACKROCK INC.	10.47%	4.41M	100.08M	1.97M	+80.53%
Dec 31, 2023	UBS GROUP AG	0.33%	138.65K	3.15M	103.66K	+296.32%
Dec 31, 2023	BARCLAYS PLC	0.31%	129.07K	2.93M	64.49K	+99.85%
Dec 31, 2023	ENSIGN PEAK ADVISORS, INC	0.28%	118K	2.68M	118K	+100.00%
Dec 31, 2023	CAPTION MANAGEMENT, LLC	0.24%	100K	2.27M	100K	+100.00%
Dec 31, 2023	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	0.23%	96.31K	2.19M	305	+0.32%
Dec 31, 2023	WELLINGTON MANAGEMENT GROUP LLP	1.28%	539.88K	12.26M	539.88K	+100.00%
Dec 31, 2023	PRICE T ROWE ASSOCIATES INC /MD/	1.25%	527.77K	11.98M	512.45K	+3,346.07%
Dec 31, 2023	INTEGRAL HEALTH ASSET MANAGEMENT, LLC	1.23%	520K	11.8M	190K	+57.58%
Dec 31, 2023	TCG CROSSOVER MANAGEMENT, LLC	1.16%	486.8K	11.05M	0	0
Dec 31, 2023		0.42%	175.36K	3.98M	175.36K	+100.00%
Dec 31, 2023	SOFINNOVA INVESTMENTS, INC.	1.02%	429.4K	9.75M	429.4K	+100.00%
Dec 31, 2023	VICTORY CAPITAL MANAGEMENT INC	0.96%	403.93K	9.17M	337.28K	+506.04%
Dec 31, 2023	MORGAN STANLEY	0.92%	387.38K	8.79M	165.37K	+74.48%
Dec 31, 2023	ALKEON CAPITAL MANAGEMENT LLC	0.85%	360K	8.17M	360K	+100.00%
Dec 31, 2023	TD ASSET MANAGEMENT INC	0.22%	93.63K	2.13M	93.63K	+100.00%
Dec 31, 2023	ROYAL BANK OF CANADA	0.23%	96.96K	2.2M	-7.81K	-7.45%
Dec 31, 2023	POLAR CAPITAL HOLDINGS PLC	2.97%	1.25M	28.38M	1.25M	+100.00%
Dec 31, 2023	REDMILE GROUP, LLC	3.26%	1.37M	31.19M	-400.06K	-22.55%
Dec 31, 2023	INVESCO LTD.	3.32%	1.4M	31.73M	543.9K	+63.69%
Dec 31, 2023	JENNISON ASSOCIATES LLC	3.86%	1.63M	36.92M	204.26K	+14.36%
Dec 31, 2023	T. ROWE PRICE INVESTMENT MANAGEMENT, INC.	4.35%	1.83M	41.61M	1.83M	+100.00%
Dec 31, 2023	COMMODORE CAPITAL LP	4.51%	1.9M	43.13M	-625.75K	-24.77%
Dec 31, 2023	HOLOCENE ADVISORS, LP	4.56%	1.92M	43.59M	737.28K	+62.32%
Dec 31, 2023	BLACKSTONE INC.	0.83%	347.49K	7.89M	347.49K	+100.00%

Insiders

Insiders	Designation	Shares Held
NICHTBERGER STEVEN	President & CEO	1.03M
FLYNN JAMES E	10 percent owner	700K
5AM VENTURES V, L.P.	10 percent owner	333.14K
SIMON MARK	director	147.21K
MARDA ANUP	Chief Financial Officer	50K
BINDER GWENDOLYN	President, Science & Tech.	31.31K
TOMASELLO SHAWN	director	22.73K
GAVEL STEVE	Chief Commercial Officer	22.17K
CHANG DAVID J.	Chief Medical Officer	8.8K
GERARD MICHAEL	General Counsel	6.6K
BOLLARD CATHERINE	director	5.41K

Buying/Selling by Insiders

Date	Insider	Type	Cost	Shares	Value ($)	Shares Total
Jan 21, 2026	CHANG DAVID J.	PURCHASE	2.26	8.8K	19.89K	8.8K
Jan 21, 2026	NICHTBERGER STEVEN	PURCHASE	2.24	45K	100.78K	1.03M
Jan 21, 2026	BOLLARD CATHERINE	PURCHASE	2.27	4.41K	9.98K	5.41K
Jan 21, 2026	SIMON MARK	PURCHASE	2.28	11.06K	25.26K	147.21K
Jan 21, 2026	GAVEL STEVE	PURCHASE	2.27	22.17K	50.22K	22.17K
Jan 21, 2026	TOMASELLO SHAWN	PURCHASE	2.21	22.73K	50.32K	22.73K
Jan 21, 2026	BINDER GWENDOLYN	PURCHASE	2.19	11.31K	24.76K	31.31K
Jan 21, 2026	GERARD MICHAEL	PURCHASE	2.27	6.6K	14.98K	6.6K
Jan 19, 2024	BINDER GWENDOLYN	SALE	20.33	700	14.23K	20K
Dec 19, 2023	BINDER GWENDOLYN	SALE	22.22	3.13K	69.59K	20K
Nov 20, 2023	BINDER GWENDOLYN	SALE	18.02	7.46K	134.41K	20K
Oct 19, 2023	BINDER GWENDOLYN	SALE	14.28	408	5.82K	20K
Sep 19, 2023	BINDER GWENDOLYN	SALE	18.50	700	12.95K	20K
Aug 21, 2023	BINDER GWENDOLYN	SALE	13.82	300	4.15K	20K
Jul 19, 2023	BINDER GWENDOLYN	SALE	14.26	2.82K	40.14K	20K
Jun 20, 2023	BINDER GWENDOLYN	SALE	12.99	11K	142.93K	20K
May 19, 2023	BINDER GWENDOLYN	SALE	11.81	22K	259.83K	20K
Oct 19, 2022	NICHTBERGER STEVEN	PURCHASE	1.25	8.13K	10.15K	986.48K
Oct 18, 2022	SIMON MARK	PURCHASE	0.98	7K	6.83K	7K
Oct 18, 2022	BINDER GWENDOLYN	PURCHASE	0.99	20K	19.89K	20K
Oct 18, 2022	BOLLARD CATHERINE	PURCHASE	0.99	1K	993.5	1K
Oct 18, 2022	MARDA ANUP	PURCHASE	0.99	50K	49.62K	50K
Oct 18, 2022	NICHTBERGER STEVEN	PURCHASE	0.99	141.87K	141.01K	978.36K
Nov 01, 2021	5AM VENTURES V, L.P.	SALE	13.00	36.54K	475.07K	333.14K
Sep 07, 2021	5AM VENTURES V, L.P.	SALE	9.70	625K	6.06M	1.99M
Jan 12, 2021	5AM VENTURES V, L.P.	SALE	13.00	10.53K	136.89K	369.69K
Jan 08, 2021	5AM VENTURES V, L.P.	SALE	13.00	37.41K	486.34K	380.22K
Dec 10, 2020	5AM VENTURES V, L.P.	SALE	14.75	36.92K	544.51K	417.63K
Oct 29, 2019	5AM VENTURES V, L.P.	PURCHASE	11.00	454.55K	5M	454.55K
Oct 29, 2019	FLYNN JAMES E	PURCHASE	11.00	700K	7.7M	700K

Insider Transaction Summary (6 Months)

SHARESTRANS

PURCHASE132.07K8

SALES00

NET SHARES132.07K8

SHARES HELD1.28M8

% NET SHARES-89.65%0%

CABA Stock Ownership Breakdown

Cabaletta Bio

Stock Outstanding Shares

Market Insider

Institutional Ownership

Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions

Stock Outstanding Shares

Market Insider

Institutional Ownership

Insiders

Buying/Selling by Insiders

Insider Transaction Summary (6 Months)

Frequently Asked Questions