Summary
• Compass Therapeutics, Inc. (CMPX) saw a 5% increase in pre-market trading, reaching $5.24 following recent leadership appointments.
• Arjun Prasad and Dr. Cynthia Sirard were appointed as Chief Commercial Officer and Chief Medical Officer, effective January 1, 2026, to support the company’s strategic goals.
• Analysts have upgraded CMPX to an outperform rating, reflecting positive sentiment amidst the firm’s leadership changes and ongoing development of antibody-based therapeutics.
Compass Therapeutics, Inc. (CMPX) is trading at $5.24 in pre-market hours, marking a 5% increase from the last close of $4.99. This move follows recent leadership changes announced by the company.
Leadership Changes Drive Investor Interest
On January 5, 2026, Compass Therapeutics revealed the appointment of Arjun Prasad as Chief Commercial Officer and Dr. Cynthia Sirard as Chief Medical Officer, both effective January 1, 2026. The company emphasizes that these appointments align with their strategic goals as they continue to develop proprietary antibody-based therapeutics aimed at treating multiple serious diseases.
These changes come amidst a broader context of the company’s operations, illustrating its commitment to securing qualified leadership capable of steering its innovative pipeline in the competitive biopharmaceutical landscape.
Inducement Grants Announcement
Additionally, on the same day, Compass announced that it has granted stock options to two new employees as part of its 2025 Inducement Plan. This move, consistent with Nasdaq Listing Rule 5635(c)(4), is intended as a material inducement to attract and retain key talent in its growing organization.
Market and Technical Picture
In reviewing market performance, the stock’s 10-day average volume stands at approximately 1.4 million shares, with a 3-month average of about 1.9 million shares. Currently, the stock has been exhibiting a quarterly performance gain of 44%, indicating a strong upward trend in this recent period. The Relative Strength Index (RSI) is currently at 46.81, suggesting that the stock is approaching the neutral zone after some fluctuations in recent trading sessions.
The stock’s performance is tempered by a year-to-date decline of roughly 7%, yet a half-year performance increase of 79% highlights the potential recovery from earlier downturns.
Analyst Sentiment
Analysts are optimistic, with a recent upgrade from William Blair, where analyst Matt Phipps initiated coverage on Compass Therapeutics with an outperform rating. This sentiment adds to the positive outlook in light of the corporate developments taking place within the company.
With an active market response to the leadership changes and a strategic vision on display, Compass Therapeutics appears to be garnering renewed attention. Investors will be keen to see how these efforts translate into sustained trading momentum as the company continues to navigate the dynamic biopharmaceutical landscape.


