Summary
• CASI Pharmaceuticals (NASDAQ: CASI) is down 6% in pre-market trading, currently priced at $0.7047, with no clear catalyst for the decline.
• The company received an extension from the Nasdaq Hearings Panel for continued listing, pending compliance by February 2026, amidst efforts to advance CID-103’s development.
• CASI has faced significant financial challenges, with a 75% stock loss over the past year and low trading activity, despite analysts maintaining a “Buy” rating.
CASI Pharmaceuticals, Inc. (NASDAQ: CASI) is trading at $0.7047 in pre-market, down 6% from its last close of $0.7532. The recent price action indicates a decline without a clear catalyst driving this movement.
Recent Market Developments
On December 23, 2025, CASI announced that the Nasdaq Hearings Panel granted its request for a continued listing, contingent upon the company regaining compliance with the Market Value of Listed Securities rule by February 17, 2026. This extension is based on the panel’s review of recent corporate developments, including the appointment of a new Chief Executive Officer and Non-Executive Chairman, and ongoing initiatives for financing and asset management.
The company’s noted efforts to advance the development of CID-103, an anti-CD38 monoclonal antibody aimed at combating organ transplant rejection and autoimmune diseases, are pivotal for its market positioning.
Financial Context and Performance Metrics
CASI’s latest performance metrics reflect significant challenges. Over the last year, the stock has lost 75%, with the year-to-date drop standing at 73%. The stock has an average volume of 22,657 over the last ten days, which is considerably lower than the three-month average volume of 112,846. This discrepancy suggests a lack of robust trading activity, indicative of broader investor caution.
Technical Analysis Insights
The technical indicators for CASI also present a cautionary picture. The current Relative Strength Index (RSI) stands at 25.91, suggesting the stock is in oversold territory. Additionally, short-term moving averages illustrate persistent declines, with the 20-day simple moving average down by 17.1%, the 50-day down 39.1%, and the 200-day down 55.7%. Such metrics could impact investor outlook as price recovery appears challenged in the current market environment.
Analyst Sentiment Overview
Despite recent struggles, CASI carries a “Buy” rating from analysts, which indicates some level of confidence in its long-term potential. The company’s recent surprise performance, recording a negative earnings surprise of 67.5% in its last report compared to expectations, is likely contributing to mixed sentiment among traders.
The stock’s recent decline underlines ongoing concerns about its ability to overcome financial hurdles and deliver on its strategic plans.
With no fresh catalyst in play, the move reflects routine market activity as participants evaluate short-term positioning. Investors will be monitoring the developments closely as the stock prepares for the next trading sessions.


